

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 8.40733352 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 8.36037589 |
| 3 | negative thymic T cell selection (GO:0045060) | 7.75367181 |
| 4 | regulation of gamma-delta T cell differentiation (GO:0045586) | 7.35757246 |
| 5 | positive T cell selection (GO:0043368) | 7.33750709 |
| 6 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 7.31455534 |
| 7 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 7.31455534 |
| 8 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 7.04390130 |
| 9 | negative regulation of cell killing (GO:0031342) | 7.04390130 |
| 10 | positive thymic T cell selection (GO:0045059) | 7.02104977 |
| 11 | thymic T cell selection (GO:0045061) | 6.61256616 |
| 12 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.59980042 |
| 13 | T cell selection (GO:0045058) | 6.58542572 |
| 14 | regulation of gamma-delta T cell activation (GO:0046643) | 6.57456134 |
| 15 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.55878650 |
| 16 | regulation of isotype switching to IgG isotypes (GO:0048302) | 6.18337221 |
| 17 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.03647461 |
| 18 | interferon-gamma production (GO:0032609) | 5.93545839 |
| 19 | response to interleukin-15 (GO:0070672) | 5.73956861 |
| 20 | T cell receptor signaling pathway (GO:0050852) | 5.62000161 |
| 21 | regulation of T cell tolerance induction (GO:0002664) | 5.39284471 |
| 22 | cellular response to interleukin-15 (GO:0071350) | 5.20925380 |
| 23 | T cell costimulation (GO:0031295) | 4.99924651 |
| 24 | T cell migration (GO:0072678) | 4.99386303 |
| 25 | lymphocyte costimulation (GO:0031294) | 4.93566160 |
| 26 | activated T cell proliferation (GO:0050798) | 4.83275810 |
| 27 | leukocyte aggregation (GO:0070486) | 4.75255483 |
| 28 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.70841098 |
| 29 | regulation of regulatory T cell differentiation (GO:0045589) | 4.66869826 |
| 30 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.60092210 |
| 31 | positive regulation of interleukin-2 production (GO:0032743) | 4.46534072 |
| 32 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.44308972 |
| 33 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.41978099 |
| 34 | positive regulation of tolerance induction (GO:0002645) | 4.40274066 |
| 35 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.20632894 |
| 36 | negative regulation of T cell mediated immunity (GO:0002710) | 4.17424262 |
| 37 | mast cell activation (GO:0045576) | 4.14926188 |
| 38 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.13429796 |
| 39 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.09078603 |
| 40 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.08749711 |
| 41 | V(D)J recombination (GO:0033151) | 4.02681036 |
| 42 | T cell differentiation (GO:0030217) | 3.98108548 |
| 43 | positive regulation of isotype switching (GO:0045830) | 3.97252232 |
| 44 | regulation of isotype switching (GO:0045191) | 3.95705500 |
| 45 | alpha-beta T cell differentiation (GO:0046632) | 3.88687223 |
| 46 | alpha-beta T cell activation (GO:0046631) | 3.88232065 |
| 47 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.85500020 |
| 48 | ribosomal small subunit assembly (GO:0000028) | 3.82116078 |
| 49 | regulation of tolerance induction (GO:0002643) | 3.80485734 |
| 50 | viral transcription (GO:0019083) | 3.79825193 |
| 51 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.67836423 |
| 52 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.67836423 |
| 53 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.67572724 |
| 54 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.67572724 |
| 55 | T cell homeostasis (GO:0043029) | 3.65025503 |
| 56 | tolerance induction (GO:0002507) | 3.61870211 |
| 57 | positive regulation of humoral immune response (GO:0002922) | 3.61284285 |
| 58 | translational termination (GO:0006415) | 3.58544568 |
| 59 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.48348369 |
| 60 | positive regulation of B cell mediated immunity (GO:0002714) | 3.48348369 |
| 61 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.47503647 |
| 62 | regulation of B cell mediated immunity (GO:0002712) | 3.45062818 |
| 63 | regulation of interleukin-2 production (GO:0032663) | 3.41768721 |
| 64 | T cell activation (GO:0042110) | 3.40947398 |
| 65 | regulation of defense response to virus by virus (GO:0050690) | 3.39904411 |
| 66 | regulation of response to interferon-gamma (GO:0060330) | 3.39857118 |
| 67 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.39766528 |
| 68 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.38416180 |
| 69 | ribosomal small subunit biogenesis (GO:0042274) | 3.35441195 |
| 70 | positive regulation of DNA recombination (GO:0045911) | 3.35425914 |
| 71 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.33069827 |
| 72 | regulation of B cell differentiation (GO:0045577) | 3.32730900 |
| 73 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.32485005 |
| 74 | positive regulation of B cell differentiation (GO:0045579) | 3.31545594 |
| 75 | cellular response to interleukin-4 (GO:0071353) | 3.28914264 |
| 76 | mast cell activation involved in immune response (GO:0002279) | 3.26611385 |
| 77 | mast cell degranulation (GO:0043303) | 3.26611385 |
| 78 | regulation of immunoglobulin production (GO:0002637) | 3.26127013 |
| 79 | NIK/NF-kappaB signaling (GO:0038061) | 3.25895388 |
| 80 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.14637286 |
| 81 | leukocyte cell-cell adhesion (GO:0007159) | 3.13828968 |
| 82 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.12736922 |
| 83 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.12687957 |
| 84 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.11164762 |
| 85 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.10750552 |
| 86 | positive regulation of granulocyte differentiation (GO:0030854) | 3.09477256 |
| 87 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.09073620 |
| 88 | positive regulation of immunoglobulin production (GO:0002639) | 3.08412467 |
| 89 | translational elongation (GO:0006414) | 3.08342220 |
| 90 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.08255497 |
| 91 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.06207266 |
| 92 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.05532434 |
| 93 | lymphocyte homeostasis (GO:0002260) | 3.04812745 |
| 94 | response to interleukin-4 (GO:0070670) | 3.04068668 |
| 95 | T cell proliferation (GO:0042098) | 3.03312377 |
| 96 | positive regulation of T cell activation (GO:0050870) | 3.00512401 |
| 97 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.98440596 |
| 98 | natural killer cell differentiation (GO:0001779) | 2.96401570 |
| 99 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.92218409 |
| 100 | natural killer cell activation (GO:0030101) | 2.91401531 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.79314243 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.89077329 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.66339992 |
| 4 | MYC_22102868_ChIP-Seq_BL_Human | 3.94200738 |
| 5 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.71903971 |
| 6 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.60581543 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.43156847 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.33269872 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.21642675 |
| 10 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.10241792 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.00897371 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.99879010 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.99560296 |
| 14 | MAF_26560356_Chip-Seq_TH1_Human | 2.88297729 |
| 15 | UTX_26944678_Chip-Seq_JUKART_Human | 2.79338312 |
| 16 | MYB_26560356_Chip-Seq_TH1_Human | 2.65101336 |
| 17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.57953687 |
| 18 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.45897287 |
| 19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.44099275 |
| 20 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.36588623 |
| 21 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.26363823 |
| 22 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.25853264 |
| 23 | MAF_26560356_Chip-Seq_TH2_Human | 2.20162749 |
| 24 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.19093922 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.10919797 |
| 26 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.09795979 |
| 27 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.06626299 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.06485817 |
| 29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.96976054 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.95940430 |
| 31 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.88363826 |
| 32 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.84830107 |
| 33 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.83163304 |
| 34 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.82143329 |
| 35 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.82079421 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81241890 |
| 37 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.79067119 |
| 38 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.76738624 |
| 39 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.74972416 |
| 40 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.72086060 |
| 41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.70767058 |
| 42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.65352246 |
| 43 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.58305784 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45091256 |
| 45 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.44439912 |
| 46 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.40755545 |
| 47 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.40104637 |
| 48 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.39981028 |
| 49 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37123359 |
| 50 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.35394980 |
| 51 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.32614835 |
| 52 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.32311750 |
| 53 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.31017516 |
| 54 | SPI1_23127762_ChIP-Seq_K562_Human | 1.30530649 |
| 55 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.29611164 |
| 56 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.28850838 |
| 57 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.25341502 |
| 58 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.22266181 |
| 59 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.15713613 |
| 60 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.13893618 |
| 61 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.13542068 |
| 62 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.13313395 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.13044808 |
| 64 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.12525854 |
| 65 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.10639119 |
| 66 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.06448581 |
| 67 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.05835771 |
| 68 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.05783847 |
| 69 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05690747 |
| 70 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.05177678 |
| 71 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.04329186 |
| 72 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00872548 |
| 73 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.99388177 |
| 74 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.97939419 |
| 75 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.97353700 |
| 76 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.96275132 |
| 77 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95617261 |
| 78 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91359585 |
| 79 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.88826291 |
| 80 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.87801307 |
| 81 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.87795432 |
| 82 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.87513879 |
| 83 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87243421 |
| 84 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.86655618 |
| 85 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84476603 |
| 86 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83289293 |
| 87 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82291159 |
| 88 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.80887665 |
| 89 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.80638527 |
| 90 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.77528233 |
| 91 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.76514382 |
| 92 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.75694027 |
| 93 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.75342035 |
| 94 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.73101240 |
| 95 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.70923592 |
| 96 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.69031448 |
| 97 | GATA1_19941826_ChIP-Seq_K562_Human | 0.66858868 |
| 98 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.65674259 |
| 99 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.65523078 |
| 100 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.64368684 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 6.35791694 |
| 2 | MP0005671_abnormal_response_to | 4.27008544 |
| 3 | MP0000685_abnormal_immune_system | 3.69505225 |
| 4 | MP0002166_altered_tumor_susceptibility | 3.16096375 |
| 5 | MP0000703_abnormal_thymus_morphology | 3.10183601 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 3.03701652 |
| 7 | MP0001800_abnormal_humoral_immune | 3.01325403 |
| 8 | MP0002398_abnormal_bone_marrow | 2.99354812 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.98164067 |
| 10 | MP0002420_abnormal_adaptive_immunity | 2.74911806 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.70576872 |
| 12 | MP0001819_abnormal_immune_cell | 2.70298525 |
| 13 | MP0003300_gastrointestinal_ulcer | 2.67050625 |
| 14 | MP0002723_abnormal_immune_serum | 2.64260500 |
| 15 | MP0001790_abnormal_immune_system | 2.61545822 |
| 16 | MP0005387_immune_system_phenotype | 2.61545822 |
| 17 | MP0002006_tumorigenesis | 2.59985715 |
| 18 | MP0002396_abnormal_hematopoietic_system | 2.56058213 |
| 19 | MP0000716_abnormal_immune_system | 2.53295144 |
| 20 | MP0002405_respiratory_system_inflammati | 2.48011190 |
| 21 | MP0002722_abnormal_immune_system | 2.46505963 |
| 22 | MP0001873_stomach_inflammation | 2.41825637 |
| 23 | MP0002452_abnormal_antigen_presenting | 2.36844822 |
| 24 | MP0003866_abnormal_defecation | 2.35278955 |
| 25 | MP0000689_abnormal_spleen_morphology | 2.33326888 |
| 26 | MP0003724_increased_susceptibility_to | 2.27354861 |
| 27 | MP0010155_abnormal_intestine_physiology | 2.23686785 |
| 28 | MP0009785_altered_susceptibility_to | 2.20581667 |
| 29 | MP0005025_abnormal_response_to | 2.18408834 |
| 30 | MP0003436_decreased_susceptibility_to | 2.18028548 |
| 31 | MP0003303_peritoneal_inflammation | 2.10233340 |
| 32 | MP0002429_abnormal_blood_cell | 2.08537706 |
| 33 | MP0004947_skin_inflammation | 2.07679451 |
| 34 | MP0006082_CNS_inflammation | 2.01557282 |
| 35 | MP0001853_heart_inflammation | 1.81086113 |
| 36 | MP0002933_joint_inflammation | 1.77398514 |
| 37 | MP0002132_abnormal_respiratory_system | 1.74022481 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.67066315 |
| 39 | MP0004808_abnormal_hematopoietic_stem | 1.64283128 |
| 40 | MP0001545_abnormal_hematopoietic_system | 1.63509448 |
| 41 | MP0005397_hematopoietic_system_phenotyp | 1.63509448 |
| 42 | MP0001845_abnormal_inflammatory_respons | 1.57919506 |
| 43 | MP0002419_abnormal_innate_immunity | 1.57161376 |
| 44 | MP0004381_abnormal_hair_follicle | 1.56640749 |
| 45 | MP0002148_abnormal_hypersensitivity_rea | 1.56632248 |
| 46 | MP0000490_abnormal_crypts_of | 1.43456793 |
| 47 | MP0000465_gastrointestinal_hemorrhage | 1.42794330 |
| 48 | MP0005075_abnormal_melanosome_morpholog | 1.41802345 |
| 49 | MP0004510_myositis | 1.36085080 |
| 50 | MP0008961_abnormal_basal_metabolism | 1.34021686 |
| 51 | MP0000858_altered_metastatic_potential | 1.31221682 |
| 52 | MP0010352_gastrointestinal_tract_polyps | 1.28206672 |
| 53 | MP0008057_abnormal_DNA_replication | 1.18840040 |
| 54 | MP0005310_abnormal_salivary_gland | 1.13216933 |
| 55 | MP0002019_abnormal_tumor_incidence | 1.11892111 |
| 56 | MP0003077_abnormal_cell_cycle | 0.97124105 |
| 57 | MP0001533_abnormal_skeleton_physiology | 0.96185266 |
| 58 | MP0010094_abnormal_chromosome_stability | 0.94985065 |
| 59 | MP0008469_abnormal_protein_level | 0.94641418 |
| 60 | MP0002009_preneoplasia | 0.93422811 |
| 61 | MP0003448_altered_tumor_morphology | 0.85892977 |
| 62 | MP0003693_abnormal_embryo_hatching | 0.84229849 |
| 63 | MP0002138_abnormal_hepatobiliary_system | 0.82829542 |
| 64 | MP0005023_abnormal_wound_healing | 0.82788601 |
| 65 | MP0009278_abnormal_bone_marrow | 0.81055553 |
| 66 | MP0004957_abnormal_blastocyst_morpholog | 0.77594447 |
| 67 | MP0001348_abnormal_lacrimal_gland | 0.76909174 |
| 68 | MP0001851_eye_inflammation | 0.76449230 |
| 69 | MP0009765_abnormal_xenobiotic_induced | 0.73058716 |
| 70 | MP0002998_abnormal_bone_remodeling | 0.71934222 |
| 71 | MP0001663_abnormal_digestive_system | 0.71247877 |
| 72 | MP0008007_abnormal_cellular_replicative | 0.70428195 |
| 73 | MP0000609_abnormal_liver_physiology | 0.69635552 |
| 74 | MP0005174_abnormal_tail_pigmentation | 0.68325443 |
| 75 | MP0009763_increased_sensitivity_to | 0.68159617 |
| 76 | MP0000477_abnormal_intestine_morphology | 0.64346153 |
| 77 | MP0001243_abnormal_dermal_layer | 0.60384125 |
| 78 | MP0000350_abnormal_cell_proliferation | 0.59951391 |
| 79 | MP0003795_abnormal_bone_structure | 0.59399242 |
| 80 | MP0000313_abnormal_cell_death | 0.53245128 |
| 81 | MP0004185_abnormal_adipocyte_glucose | 0.49649141 |
| 82 | MP0008770_decreased_survivor_rate | 0.47434258 |
| 83 | MP0003111_abnormal_nucleus_morphology | 0.46568777 |
| 84 | MP0008873_increased_physiological_sensi | 0.45884845 |
| 85 | MP0002822_catalepsy | 0.42240197 |
| 86 | MP0000604_amyloidosis | 0.42184672 |
| 87 | MP0002095_abnormal_skin_pigmentation | 0.40992928 |
| 88 | MP0001191_abnormal_skin_condition | 0.40890993 |
| 89 | MP0001730_embryonic_growth_arrest | 0.39938637 |
| 90 | MP0000367_abnormal_coat/_hair | 0.39851879 |
| 91 | MP0003453_abnormal_keratinocyte_physiol | 0.39537084 |
| 92 | MP0001216_abnormal_epidermal_layer | 0.39488985 |
| 93 | MP0002083_premature_death | 0.38884880 |
| 94 | MP0002136_abnormal_kidney_physiology | 0.36457789 |
| 95 | MP0002970_abnormal_white_adipose | 0.36239746 |
| 96 | MP0003045_fibrosis | 0.36105875 |
| 97 | MP0008569_lethality_at_weaning | 0.35633705 |
| 98 | MP0003959_abnormal_lean_body | 0.35395621 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.33787878 |
| 100 | MP0009764_decreased_sensitivity_to | 0.33287337 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 8.85609045 |
| 2 | Abnormality of T cell number (HP:0011839) | 8.43599387 |
| 3 | Severe combined immunodeficiency (HP:0004430) | 5.66997061 |
| 4 | Abnormality of T cells (HP:0002843) | 5.63110984 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.43273690 |
| 6 | Combined immunodeficiency (HP:0005387) | 5.41307670 |
| 7 | Chronic otitis media (HP:0000389) | 5.36278955 |
| 8 | Panhypogammaglobulinemia (HP:0003139) | 5.32008139 |
| 9 | Recurrent viral infections (HP:0004429) | 5.20931489 |
| 10 | Stomatitis (HP:0010280) | 4.80699669 |
| 11 | Recurrent bronchitis (HP:0002837) | 4.64427822 |
| 12 | Nasal polyposis (HP:0100582) | 4.63791133 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.59187182 |
| 14 | Eosinophilia (HP:0001880) | 4.34294897 |
| 15 | Abnormality of B cell number (HP:0010975) | 4.28169465 |
| 16 | B lymphocytopenia (HP:0010976) | 4.28169465 |
| 17 | IgG deficiency (HP:0004315) | 4.23336940 |
| 18 | Abnormality of eosinophils (HP:0001879) | 4.12797540 |
| 19 | Abnormality of the nasal mucosa (HP:0000433) | 3.90606262 |
| 20 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.83444188 |
| 21 | IgM deficiency (HP:0002850) | 3.80240925 |
| 22 | Granulocytopenia (HP:0001913) | 3.76896620 |
| 23 | Abnormality of the fingertips (HP:0001211) | 3.76344423 |
| 24 | Leukocytosis (HP:0001974) | 3.65333582 |
| 25 | Hypoplasia of the thymus (HP:0000778) | 3.56483058 |
| 26 | Pustule (HP:0200039) | 3.48968118 |
| 27 | Thyroiditis (HP:0100646) | 3.46604997 |
| 28 | Autoimmune hemolytic anemia (HP:0001890) | 3.38908072 |
| 29 | Recurrent cutaneous fungal infections (HP:0011370) | 3.35059097 |
| 30 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.35059097 |
| 31 | Myositis (HP:0100614) | 3.21928718 |
| 32 | Joint swelling (HP:0001386) | 3.18280015 |
| 33 | Basal cell carcinoma (HP:0002671) | 3.14697133 |
| 34 | Abnormality of T cell physiology (HP:0011840) | 3.12752032 |
| 35 | Lymphopenia (HP:0001888) | 3.08774430 |
| 36 | Spontaneous hematomas (HP:0007420) | 3.06891927 |
| 37 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.03233700 |
| 38 | Eczematoid dermatitis (HP:0000976) | 2.97902063 |
| 39 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.96236355 |
| 40 | Chronic diarrhea (HP:0002028) | 2.86380708 |
| 41 | Abnormal number of erythroid precursors (HP:0012131) | 2.85993443 |
| 42 | Encephalitis (HP:0002383) | 2.82415109 |
| 43 | Meningitis (HP:0001287) | 2.82233365 |
| 44 | Increased IgM level (HP:0003496) | 2.80856170 |
| 45 | Thrombocytosis (HP:0001894) | 2.79231636 |
| 46 | Autoimmune thrombocytopenia (HP:0001973) | 2.78832071 |
| 47 | Lymphoma (HP:0002665) | 2.76486487 |
| 48 | Bronchitis (HP:0012387) | 2.66621891 |
| 49 | Hemoptysis (HP:0002105) | 2.63958817 |
| 50 | Gastrointestinal infarctions (HP:0005244) | 2.61919939 |
| 51 | Chronic sinusitis (HP:0011109) | 2.57477887 |
| 52 | Increased IgE level (HP:0003212) | 2.53061737 |
| 53 | Abnormal platelet volume (HP:0011876) | 2.49568669 |
| 54 | Epistaxis (HP:0000421) | 2.48523849 |
| 55 | Papilloma (HP:0012740) | 2.48021473 |
| 56 | Verrucae (HP:0200043) | 2.48021473 |
| 57 | Inflammation of the large intestine (HP:0002037) | 2.45511282 |
| 58 | Petechiae (HP:0000967) | 2.44525381 |
| 59 | Chest pain (HP:0100749) | 2.40353585 |
| 60 | Vasculitis (HP:0002633) | 2.40025041 |
| 61 | Hypergammaglobulinemia (HP:0010702) | 2.39754500 |
| 62 | Gastrointestinal inflammation (HP:0004386) | 2.39553905 |
| 63 | Prolonged bleeding time (HP:0003010) | 2.38042495 |
| 64 | Abnormality of the prostate (HP:0008775) | 2.32916208 |
| 65 | Pulmonary infiltrates (HP:0002113) | 2.30230250 |
| 66 | IgA deficiency (HP:0002720) | 2.29335787 |
| 67 | Retrobulbar optic neuritis (HP:0100654) | 2.28369546 |
| 68 | Optic neuritis (HP:0100653) | 2.28369546 |
| 69 | Ureteral stenosis (HP:0000071) | 2.25066551 |
| 70 | Mediastinal lymphadenopathy (HP:0100721) | 2.23379832 |
| 71 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.21996986 |
| 72 | Pulmonary embolism (HP:0002204) | 2.15983593 |
| 73 | Recurrent abscess formation (HP:0002722) | 2.14383238 |
| 74 | Bicuspid aortic valve (HP:0001647) | 2.13094311 |
| 75 | Obstructive lung disease (HP:0006536) | 2.11510751 |
| 76 | Chronic obstructive pulmonary disease (HP:0006510) | 2.11510751 |
| 77 | Recurrent sinusitis (HP:0011108) | 2.10594908 |
| 78 | Hepatitis (HP:0012115) | 2.09869617 |
| 79 | Cellular immunodeficiency (HP:0005374) | 2.09027651 |
| 80 | Amaurosis fugax (HP:0100576) | 2.07311500 |
| 81 | Poikiloderma (HP:0001029) | 2.06863507 |
| 82 | Recurrent otitis media (HP:0000403) | 2.06847297 |
| 83 | Recurrent skin infections (HP:0001581) | 2.04952467 |
| 84 | Gingival bleeding (HP:0000225) | 2.01007035 |
| 85 | Ureteral obstruction (HP:0006000) | 2.00900684 |
| 86 | Orchitis (HP:0100796) | 1.97719201 |
| 87 | Increased mean platelet volume (HP:0011877) | 1.96891695 |
| 88 | Arterial thrombosis (HP:0004420) | 1.95652270 |
| 89 | Reticulocytopenia (HP:0001896) | 1.95160890 |
| 90 | Agammaglobulinemia (HP:0004432) | 1.94516231 |
| 91 | Bronchiectasis (HP:0002110) | 1.91027471 |
| 92 | Broad palm (HP:0001169) | 1.86438164 |
| 93 | Macrocytic anemia (HP:0001972) | 1.85442971 |
| 94 | Keratoconjunctivitis sicca (HP:0001097) | 1.82943117 |
| 95 | Pallor (HP:0000980) | 1.82850734 |
| 96 | Increased density of long bones (HP:0006392) | 1.82271346 |
| 97 | Fatigue (HP:0012378) | 1.77937183 |
| 98 | Abnormality of oral frenula (HP:0000190) | 1.77137821 |
| 99 | Abnormality of the thymus (HP:0000777) | 1.74843762 |
| 100 | Hypochromic anemia (HP:0001931) | 1.73147371 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.42555081 |
| 2 | MAP4K1 | 5.61936254 |
| 3 | ITK | 3.44023570 |
| 4 | JAK3 | 3.10045022 |
| 5 | ZAP70 | 3.08246182 |
| 6 | FGFR4 | 2.86406662 |
| 7 | STK10 | 2.70981905 |
| 8 | TYK2 | 2.39596999 |
| 9 | MAP3K10 | 2.35291463 |
| 10 | GRK6 | 2.29526569 |
| 11 | NLK | 2.26936329 |
| 12 | IKBKE | 2.16922068 |
| 13 | EEF2K | 2.16470938 |
| 14 | PKN2 | 1.90568771 |
| 15 | FGFR3 | 1.90007740 |
| 16 | TEC | 1.88024891 |
| 17 | LCK | 1.85415200 |
| 18 | MST4 | 1.70434363 |
| 19 | NME2 | 1.65706069 |
| 20 | CDK12 | 1.65346825 |
| 21 | JAK1 | 1.62040010 |
| 22 | STK16 | 1.57145427 |
| 23 | MAP3K14 | 1.52769616 |
| 24 | BTK | 1.46570669 |
| 25 | LRRK2 | 1.42917408 |
| 26 | CSK | 1.42067774 |
| 27 | SYK | 1.40989603 |
| 28 | HCK | 1.27867067 |
| 29 | MAP3K13 | 1.24547314 |
| 30 | PRKCH | 1.19755952 |
| 31 | PRKCQ | 1.17295440 |
| 32 | MAP3K7 | 1.14250232 |
| 33 | JAK2 | 1.09533700 |
| 34 | TBK1 | 1.08173915 |
| 35 | RPS6KA4 | 1.01869121 |
| 36 | ACVR1B | 1.00242286 |
| 37 | MARK3 | 0.96342014 |
| 38 | SCYL2 | 0.93535798 |
| 39 | PASK | 0.93135542 |
| 40 | IKBKB | 0.92911879 |
| 41 | PIM1 | 0.91295616 |
| 42 | TYRO3 | 0.90547482 |
| 43 | CLK1 | 0.87558383 |
| 44 | TRIB3 | 0.76623771 |
| 45 | KIT | 0.73905715 |
| 46 | CDK4 | 0.71285769 |
| 47 | FES | 0.69968845 |
| 48 | FLT3 | 0.68980435 |
| 49 | TNK2 | 0.67497516 |
| 50 | CHUK | 0.66983348 |
| 51 | MARK2 | 0.66092329 |
| 52 | TGFBR2 | 0.65136233 |
| 53 | PDGFRB | 0.63897479 |
| 54 | SIK2 | 0.62713491 |
| 55 | KDR | 0.62156614 |
| 56 | LYN | 0.62054655 |
| 57 | TGFBR1 | 0.61728199 |
| 58 | BLK | 0.61202515 |
| 59 | TTN | 0.60477429 |
| 60 | TESK2 | 0.58661391 |
| 61 | MAP2K3 | 0.58469870 |
| 62 | FGFR1 | 0.57828264 |
| 63 | FGFR2 | 0.55825156 |
| 64 | HIPK2 | 0.55496561 |
| 65 | MAPK7 | 0.55218598 |
| 66 | TAOK1 | 0.54632370 |
| 67 | EPHB1 | 0.52492232 |
| 68 | RPS6KB2 | 0.51455853 |
| 69 | IRAK4 | 0.49181402 |
| 70 | STK4 | 0.48852969 |
| 71 | ALK | 0.48458960 |
| 72 | NTRK2 | 0.48236389 |
| 73 | PDK1 | 0.45729568 |
| 74 | MELK | 0.42155265 |
| 75 | BRD4 | 0.41070443 |
| 76 | EPHA3 | 0.40521640 |
| 77 | CDK6 | 0.38932318 |
| 78 | MAP3K8 | 0.38214764 |
| 79 | INSR | 0.38106927 |
| 80 | TSSK6 | 0.36819319 |
| 81 | MAPK4 | 0.36749537 |
| 82 | FYN | 0.36489129 |
| 83 | EIF2AK1 | 0.34434465 |
| 84 | MAPK11 | 0.33935938 |
| 85 | PTK6 | 0.33293721 |
| 86 | MAPK12 | 0.32339668 |
| 87 | PIM2 | 0.32070598 |
| 88 | CDC7 | 0.30440259 |
| 89 | RPS6KA5 | 0.29607601 |
| 90 | CSF1R | 0.28540976 |
| 91 | RPS6KA6 | 0.27132680 |
| 92 | RAF1 | 0.27083246 |
| 93 | RET | 0.26363190 |
| 94 | ATR | 0.24773051 |
| 95 | MAP3K11 | 0.22733319 |
| 96 | IGF1R | 0.22505402 |
| 97 | CDK9 | 0.21813217 |
| 98 | ROCK2 | 0.21736982 |
| 99 | SGK3 | 0.21660661 |
| 100 | MAPK3 | 0.21415886 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.05447401 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.42873532 |
| 3 | Measles_Homo sapiens_hsa05162 | 2.93051501 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.79915262 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.72495268 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.66614600 |
| 7 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.52836679 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.46994477 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.31855913 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.28159989 |
| 11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.27145201 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.02673466 |
| 13 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.92588876 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.82125047 |
| 15 | Viral myocarditis_Homo sapiens_hsa05416 | 1.77142883 |
| 16 | Leishmaniasis_Homo sapiens_hsa05140 | 1.75458688 |
| 17 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.72828787 |
| 18 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.70214480 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.68479504 |
| 20 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.60803781 |
| 21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.58437965 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.46846696 |
| 23 | Hepatitis B_Homo sapiens_hsa05161 | 1.40330589 |
| 24 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.33149397 |
| 25 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.30767424 |
| 26 | HTLV-I infection_Homo sapiens_hsa05166 | 1.29025003 |
| 27 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.29018870 |
| 28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.27986552 |
| 29 | Colorectal cancer_Homo sapiens_hsa05210 | 1.26804721 |
| 30 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.25511836 |
| 31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.24448054 |
| 32 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.24422654 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20029216 |
| 34 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.19397139 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 1.14942918 |
| 36 | Shigellosis_Homo sapiens_hsa05131 | 1.12314175 |
| 37 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.12288567 |
| 38 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.06514289 |
| 39 | Platelet activation_Homo sapiens_hsa04611 | 1.00487365 |
| 40 | Influenza A_Homo sapiens_hsa05164 | 0.99952122 |
| 41 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.97899172 |
| 42 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.97632138 |
| 43 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.93311824 |
| 44 | Thyroid cancer_Homo sapiens_hsa05216 | 0.92987773 |
| 45 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91696646 |
| 46 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.90432080 |
| 47 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.88893523 |
| 48 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.88750550 |
| 49 | Apoptosis_Homo sapiens_hsa04210 | 0.87818696 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.83039310 |
| 51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.80454389 |
| 52 | Hepatitis C_Homo sapiens_hsa05160 | 0.79842196 |
| 53 | Asthma_Homo sapiens_hsa05310 | 0.79648190 |
| 54 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.79494517 |
| 55 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.78892041 |
| 56 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.78505335 |
| 57 | RNA degradation_Homo sapiens_hsa03018 | 0.74467705 |
| 58 | Legionellosis_Homo sapiens_hsa05134 | 0.70894182 |
| 59 | DNA replication_Homo sapiens_hsa03030 | 0.68158043 |
| 60 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.66915582 |
| 61 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.66828432 |
| 62 | Mismatch repair_Homo sapiens_hsa03430 | 0.64917169 |
| 63 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.63803910 |
| 64 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61572447 |
| 65 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.60823040 |
| 66 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.59322973 |
| 67 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.58817240 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57280732 |
| 69 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.56232721 |
| 70 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.54116458 |
| 71 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.53216857 |
| 72 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.53110890 |
| 73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52869797 |
| 74 | Tuberculosis_Homo sapiens_hsa05152 | 0.52790705 |
| 75 | Prostate cancer_Homo sapiens_hsa05215 | 0.51791539 |
| 76 | RNA transport_Homo sapiens_hsa03013 | 0.50705634 |
| 77 | Malaria_Homo sapiens_hsa05144 | 0.46405504 |
| 78 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.43858376 |
| 79 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40892495 |
| 80 | Salmonella infection_Homo sapiens_hsa05132 | 0.40296920 |
| 81 | Endocytosis_Homo sapiens_hsa04144 | 0.40292146 |
| 82 | Pertussis_Homo sapiens_hsa05133 | 0.39385894 |
| 83 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.38840551 |
| 84 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.37131828 |
| 85 | Base excision repair_Homo sapiens_hsa03410 | 0.36683231 |
| 86 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.35881546 |
| 87 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.35844389 |
| 88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.35840557 |
| 89 | Lysine degradation_Homo sapiens_hsa00310 | 0.34773239 |
| 90 | Insulin resistance_Homo sapiens_hsa04931 | 0.34654464 |
| 91 | Cell cycle_Homo sapiens_hsa04110 | 0.32364724 |
| 92 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.30206795 |
| 93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.29740854 |
| 94 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.28330709 |
| 95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.27851917 |
| 96 | Adherens junction_Homo sapiens_hsa04520 | 0.27774672 |
| 97 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.26200987 |
| 98 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.23908702 |
| 99 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.23846650 |
| 100 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.22600750 |

