

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | activated T cell proliferation (GO:0050798) | 7.36758096 |
| 2 | intra-S DNA damage checkpoint (GO:0031573) | 7.29860138 |
| 3 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 7.14959593 |
| 4 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 7.14959593 |
| 5 | regulation of transforming growth factor beta2 production (GO:0032909) | 6.74239608 |
| 6 | cellular response to interleukin-15 (GO:0071350) | 6.64506322 |
| 7 | macrophage differentiation (GO:0030225) | 5.86379748 |
| 8 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 5.82766442 |
| 9 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.67824494 |
| 10 | cytidine metabolic process (GO:0046087) | 5.62613414 |
| 11 | cytidine catabolic process (GO:0006216) | 5.62613414 |
| 12 | cytidine deamination (GO:0009972) | 5.62613414 |
| 13 | response to interleukin-15 (GO:0070672) | 5.62034475 |
| 14 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 5.61223221 |
| 15 | regulation of RIG-I signaling pathway (GO:0039535) | 5.54956260 |
| 16 | necroptotic process (GO:0070266) | 5.44161471 |
| 17 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 5.27528817 |
| 18 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 5.22128355 |
| 19 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 5.16442360 |
| 20 | negative regulation of viral genome replication (GO:0045071) | 5.08025129 |
| 21 | regulation of T cell tolerance induction (GO:0002664) | 5.05838782 |
| 22 | programmed necrotic cell death (GO:0097300) | 4.92958609 |
| 23 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 4.88387727 |
| 24 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.75290921 |
| 25 | positive regulation of mRNA catabolic process (GO:0061014) | 4.72701965 |
| 26 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.69194200 |
| 27 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.69194200 |
| 28 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.68555516 |
| 29 | necrotic cell death (GO:0070265) | 4.65290390 |
| 30 | negative T cell selection (GO:0043383) | 4.62906074 |
| 31 | T cell apoptotic process (GO:0070231) | 4.61211648 |
| 32 | positive regulation of transforming growth factor beta production (GO:0071636) | 4.59384336 |
| 33 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.52885933 |
| 34 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.43538032 |
| 35 | regulation of regulatory T cell differentiation (GO:0045589) | 4.38627630 |
| 36 | cellular response to arsenic-containing substance (GO:0071243) | 4.31462574 |
| 37 | positive regulation of tolerance induction (GO:0002645) | 4.30287778 |
| 38 | positive regulation of interferon-alpha production (GO:0032727) | 4.26648614 |
| 39 | negative thymic T cell selection (GO:0045060) | 4.18680170 |
| 40 | positive regulation of macrophage differentiation (GO:0045651) | 4.16320705 |
| 41 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.16039319 |
| 42 | regulation of interferon-alpha production (GO:0032647) | 4.15839805 |
| 43 | positive T cell selection (GO:0043368) | 4.13992183 |
| 44 | regulation of tolerance induction (GO:0002643) | 4.13484300 |
| 45 | positive regulation of interferon-beta production (GO:0032728) | 4.12452055 |
| 46 | regulation of mRNA catabolic process (GO:0061013) | 4.11022975 |
| 47 | negative regulation by host of viral transcription (GO:0043922) | 4.02827555 |
| 48 | T cell costimulation (GO:0031295) | 4.01223463 |
| 49 | lymphocyte apoptotic process (GO:0070227) | 3.99780127 |
| 50 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.99534500 |
| 51 | lymphocyte costimulation (GO:0031294) | 3.95640183 |
| 52 | positive thymic T cell selection (GO:0045059) | 3.91651170 |
| 53 | regulation of viral genome replication (GO:0045069) | 3.91162977 |
| 54 | tolerance induction (GO:0002507) | 3.86008370 |
| 55 | T cell migration (GO:0072678) | 3.84033977 |
| 56 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.82856601 |
| 57 | thymic T cell selection (GO:0045061) | 3.78925293 |
| 58 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.77703763 |
| 59 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.77634107 |
| 60 | positive regulation of translational initiation (GO:0045948) | 3.76180612 |
| 61 | positive regulation of cell killing (GO:0031343) | 3.70737706 |
| 62 | response to interferon-beta (GO:0035456) | 3.68916813 |
| 63 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.66224572 |
| 64 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 3.64316541 |
| 65 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.60797299 |
| 66 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.53796333 |
| 67 | negative regulation of cell killing (GO:0031342) | 3.52550420 |
| 68 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.52550420 |
| 69 | regulation of interferon-beta production (GO:0032648) | 3.49380746 |
| 70 | regulation of cell killing (GO:0031341) | 3.47150985 |
| 71 | T cell selection (GO:0045058) | 3.45059847 |
| 72 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.44481443 |
| 73 | regulation of chronic inflammatory response (GO:0002676) | 3.43070229 |
| 74 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.41768664 |
| 75 | ribosome assembly (GO:0042255) | 3.38826854 |
| 76 | DNA deamination (GO:0045006) | 3.35502917 |
| 77 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.33100689 |
| 78 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.31544556 |
| 79 | negative regulation of viral process (GO:0048525) | 3.30203277 |
| 80 | regulation of necroptotic process (GO:0060544) | 3.29293330 |
| 81 | T cell receptor signaling pathway (GO:0050852) | 3.28766424 |
| 82 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.25879981 |
| 83 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.20363917 |
| 84 | protein localization to cell surface (GO:0034394) | 3.19294685 |
| 85 | leukocyte apoptotic process (GO:0071887) | 3.19104409 |
| 86 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.14787036 |
| 87 | nucleotide-sugar metabolic process (GO:0009225) | 3.10180308 |
| 88 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.09837053 |
| 89 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.01773789 |
| 90 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.00625772 |
| 91 | regulation of activation of Janus kinase activity (GO:0010533) | 2.99943911 |
| 92 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.98346946 |
| 93 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.97297800 |
| 94 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.94196115 |
| 95 | gonadal mesoderm development (GO:0007506) | 2.93970675 |
| 96 | cellular response to type I interferon (GO:0071357) | 2.93252833 |
| 97 | type I interferon signaling pathway (GO:0060337) | 2.93252833 |
| 98 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.89125850 |
| 99 | response to type I interferon (GO:0034340) | 2.89123183 |
| 100 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.86694261 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 7.60646221 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.05328048 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.80082665 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.46045416 |
| 5 | GATA1_22025678_ChIP-Seq_K562_Human | 5.11013845 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.89869216 |
| 7 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.63360019 |
| 8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.43917903 |
| 9 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.38720115 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.22286142 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 3.19427317 |
| 12 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.18226841 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.04643279 |
| 14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.01583565 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.88678915 |
| 16 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.76181827 |
| 17 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.65625320 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.55540879 |
| 19 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.34370652 |
| 20 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.19051685 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.90510915 |
| 22 | UTX_26944678_Chip-Seq_JUKART_Human | 1.83084313 |
| 23 | MAF_26560356_Chip-Seq_TH1_Human | 1.81091675 |
| 24 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.79761034 |
| 25 | GATA3_26560356_Chip-Seq_TH2_Human | 1.74975805 |
| 26 | MAF_26560356_Chip-Seq_TH2_Human | 1.72457485 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.72004151 |
| 28 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.67604817 |
| 29 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67074210 |
| 30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.61431042 |
| 31 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.59658097 |
| 32 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57135121 |
| 33 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.46542833 |
| 34 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.46225227 |
| 35 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.39344412 |
| 36 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.38550502 |
| 37 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.37547654 |
| 38 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.37362510 |
| 39 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.28392206 |
| 40 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27476484 |
| 41 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.24833476 |
| 42 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.19942501 |
| 43 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.19100697 |
| 44 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.16144220 |
| 45 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.14312015 |
| 46 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.09184344 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06740130 |
| 48 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03438357 |
| 49 | MYC_22102868_ChIP-Seq_BL_Human | 1.01499180 |
| 50 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.00379133 |
| 51 | GATA1_19941826_ChIP-Seq_K562_Human | 0.98918056 |
| 52 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.98329764 |
| 53 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.96937346 |
| 54 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96789117 |
| 55 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95974428 |
| 56 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.92773801 |
| 57 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.91465328 |
| 58 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89115224 |
| 59 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.88496157 |
| 60 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88021167 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.87024591 |
| 62 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.86765638 |
| 63 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.85809497 |
| 64 | GATA3_26560356_Chip-Seq_TH1_Human | 0.84232757 |
| 65 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.83630842 |
| 66 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.82664361 |
| 67 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.81793561 |
| 68 | VDR_22108803_ChIP-Seq_LS180_Human | 0.80904665 |
| 69 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80014457 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.79149229 |
| 71 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79126059 |
| 72 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.78400800 |
| 73 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.77443960 |
| 74 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77290494 |
| 75 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.76607924 |
| 76 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.74792409 |
| 77 | SPI1_23127762_ChIP-Seq_K562_Human | 0.73945037 |
| 78 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.72688551 |
| 79 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.69763862 |
| 80 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.68863587 |
| 81 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.68719108 |
| 82 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.68198397 |
| 83 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.67345486 |
| 84 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.67032193 |
| 85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.66871099 |
| 86 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.65758870 |
| 87 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.64655556 |
| 88 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.64650513 |
| 89 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.64437485 |
| 90 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.62840546 |
| 91 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.62735665 |
| 92 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.62689444 |
| 93 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.62298607 |
| 94 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.62039141 |
| 95 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.61806431 |
| 96 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.61688501 |
| 97 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.61655248 |
| 98 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.61053958 |
| 99 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.60987250 |
| 100 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.60878988 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.25701968 |
| 2 | MP0005671_abnormal_response_to | 5.11101023 |
| 3 | MP0005451_abnormal_body_composition | 4.18094794 |
| 4 | MP0009785_altered_susceptibility_to | 3.86229833 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.65698028 |
| 6 | MP0001800_abnormal_humoral_immune | 3.06585104 |
| 7 | MP0002638_abnormal_pupillary_reflex | 3.04045525 |
| 8 | MP0002723_abnormal_immune_serum | 2.96091703 |
| 9 | MP0001873_stomach_inflammation | 2.92125958 |
| 10 | MP0005025_abnormal_response_to | 2.82688946 |
| 11 | MP0005076_abnormal_cell_differentiation | 2.72220367 |
| 12 | MP0002148_abnormal_hypersensitivity_rea | 2.64639704 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.62673438 |
| 14 | MP0009333_abnormal_splenocyte_physiolog | 2.62202961 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.61903695 |
| 16 | MP0001819_abnormal_immune_cell | 2.56204270 |
| 17 | MP0010155_abnormal_intestine_physiology | 2.52498859 |
| 18 | MP0001851_eye_inflammation | 2.46813104 |
| 19 | MP0006082_CNS_inflammation | 2.38910131 |
| 20 | MP0003436_decreased_susceptibility_to | 2.37134188 |
| 21 | MP0001790_abnormal_immune_system | 2.34716447 |
| 22 | MP0005387_immune_system_phenotype | 2.34716447 |
| 23 | MP0002398_abnormal_bone_marrow | 2.34602361 |
| 24 | MP0002452_abnormal_antigen_presenting | 2.32880068 |
| 25 | MP0003866_abnormal_defecation | 2.19088066 |
| 26 | MP0000716_abnormal_immune_system | 2.04981054 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.92373942 |
| 28 | MP0002166_altered_tumor_susceptibility | 1.83428061 |
| 29 | MP0002419_abnormal_innate_immunity | 1.82789581 |
| 30 | MP0000858_altered_metastatic_potential | 1.81940083 |
| 31 | MP0000703_abnormal_thymus_morphology | 1.80464680 |
| 32 | MP0005310_abnormal_salivary_gland | 1.79891316 |
| 33 | MP0000685_abnormal_immune_system | 1.76684535 |
| 34 | MP0003693_abnormal_embryo_hatching | 1.75250038 |
| 35 | MP0001845_abnormal_inflammatory_respons | 1.71553016 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.69234012 |
| 37 | MP0002405_respiratory_system_inflammati | 1.68736648 |
| 38 | MP0002722_abnormal_immune_system | 1.64088877 |
| 39 | MP0009115_abnormal_fat_cell | 1.61388216 |
| 40 | MP0002429_abnormal_blood_cell | 1.60175546 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.56573680 |
| 42 | MP0008469_abnormal_protein_level | 1.43210147 |
| 43 | MP0010386_abnormal_urinary_bladder | 1.43040513 |
| 44 | MP0002006_tumorigenesis | 1.42457957 |
| 45 | MP0002933_joint_inflammation | 1.39589428 |
| 46 | MP0008569_lethality_at_weaning | 1.28736740 |
| 47 | MP0003724_increased_susceptibility_to | 1.25578707 |
| 48 | MP0001533_abnormal_skeleton_physiology | 1.24903236 |
| 49 | MP0009765_abnormal_xenobiotic_induced | 1.22406886 |
| 50 | MP0002163_abnormal_gland_morphology | 1.15509225 |
| 51 | MP0009763_increased_sensitivity_to | 1.15019730 |
| 52 | MP0001853_heart_inflammation | 1.07411086 |
| 53 | MP0001919_abnormal_reproductive_system | 1.06039287 |
| 54 | MP0005408_hypopigmentation | 1.03351206 |
| 55 | MP0003045_fibrosis | 1.02915633 |
| 56 | MP0004134_abnormal_chest_morphology | 1.02636296 |
| 57 | MP0004130_abnormal_muscle_cell | 0.99542608 |
| 58 | MP0003786_premature_aging | 0.98323781 |
| 59 | MP0000427_abnormal_hair_cycle | 0.95444213 |
| 60 | MP0005464_abnormal_platelet_physiology | 0.91556466 |
| 61 | MP0004381_abnormal_hair_follicle | 0.90715834 |
| 62 | MP0000343_altered_response_to | 0.87744489 |
| 63 | MP0001764_abnormal_homeostasis | 0.84755331 |
| 64 | MP0002254_reproductive_system_inflammat | 0.83363680 |
| 65 | MP0004947_skin_inflammation | 0.82858063 |
| 66 | MP0003303_peritoneal_inflammation | 0.81398903 |
| 67 | MP0001727_abnormal_embryo_implantation | 0.81040541 |
| 68 | MP0001666_abnormal_nutrient_absorption | 0.79913753 |
| 69 | MP0001502_abnormal_circadian_rhythm | 0.79000640 |
| 70 | MP0001663_abnormal_digestive_system | 0.78129614 |
| 71 | MP0002693_abnormal_pancreas_physiology | 0.77426743 |
| 72 | MP0001191_abnormal_skin_condition | 0.76274313 |
| 73 | MP0000490_abnormal_crypts_of | 0.75614920 |
| 74 | MP0002019_abnormal_tumor_incidence | 0.74148058 |
| 75 | MP0009764_decreased_sensitivity_to | 0.69014324 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.65937020 |
| 77 | MP0001270_distended_abdomen | 0.62082463 |
| 78 | MP0003300_gastrointestinal_ulcer | 0.61465984 |
| 79 | MP0002970_abnormal_white_adipose | 0.54765761 |
| 80 | MP0001243_abnormal_dermal_layer | 0.52487797 |
| 81 | MP0002168_other_aberrant_phenotype | 0.52431949 |
| 82 | MP0005389_reproductive_system_phenotype | 0.51776233 |
| 83 | MP0003448_altered_tumor_morphology | 0.50126710 |
| 84 | MP0000367_abnormal_coat/_hair | 0.47925204 |
| 85 | MP0005166_decreased_susceptibility_to | 0.47646409 |
| 86 | MP0008872_abnormal_physiological_respon | 0.47216058 |
| 87 | MP0005075_abnormal_melanosome_morpholog | 0.45725666 |
| 88 | MP0004885_abnormal_endolymph | 0.43445550 |
| 89 | MP0005666_abnormal_adipose_tissue | 0.43285991 |
| 90 | MP0005390_skeleton_phenotype | 0.42060906 |
| 91 | MP0009643_abnormal_urine_homeostasis | 0.41652082 |
| 92 | MP0001348_abnormal_lacrimal_gland | 0.41550791 |
| 93 | MP0010307_abnormal_tumor_latency | 0.40872552 |
| 94 | MP0003943_abnormal_hepatobiliary_system | 0.40018440 |
| 95 | MP0005379_endocrine/exocrine_gland_phen | 0.39633454 |
| 96 | MP0004742_abnormal_vestibular_system | 0.38700856 |
| 97 | MP0001963_abnormal_hearing_physiology | 0.38077853 |
| 98 | MP0000465_gastrointestinal_hemorrhage | 0.38077270 |
| 99 | MP0001765_abnormal_ion_homeostasis | 0.37776074 |
| 100 | MP0000609_abnormal_liver_physiology | 0.37645511 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 7.33506711 |
| 2 | Abnormality of T cell number (HP:0011839) | 7.27517367 |
| 3 | Stomatitis (HP:0010280) | 5.93480161 |
| 4 | Increased IgM level (HP:0003496) | 5.28529216 |
| 5 | IgG deficiency (HP:0004315) | 5.02785381 |
| 6 | Optic neuritis (HP:0100653) | 4.81661981 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 4.81661981 |
| 8 | Chronic diarrhea (HP:0002028) | 4.62120328 |
| 9 | Abnormality of T cells (HP:0002843) | 4.54788281 |
| 10 | Orchitis (HP:0100796) | 4.32547640 |
| 11 | Joint swelling (HP:0001386) | 4.16837020 |
| 12 | Recurrent cutaneous fungal infections (HP:0011370) | 4.10640856 |
| 13 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.10640856 |
| 14 | Autoimmune hemolytic anemia (HP:0001890) | 4.07366759 |
| 15 | Hypoproteinemia (HP:0003075) | 4.07014466 |
| 16 | Myositis (HP:0100614) | 4.03768458 |
| 17 | Severe combined immunodeficiency (HP:0004430) | 4.01305115 |
| 18 | IgA deficiency (HP:0002720) | 3.85285786 |
| 19 | Pulmonary infiltrates (HP:0002113) | 3.75291342 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.72191637 |
| 21 | Vasculitis (HP:0002633) | 3.69126500 |
| 22 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.66730257 |
| 23 | Agammaglobulinemia (HP:0004432) | 3.59347991 |
| 24 | Recurrent bronchitis (HP:0002837) | 3.37870073 |
| 25 | Abnormality of eosinophils (HP:0001879) | 3.37466078 |
| 26 | Progressive inability to walk (HP:0002505) | 3.29033230 |
| 27 | Hemoptysis (HP:0002105) | 3.25968573 |
| 28 | Meningitis (HP:0001287) | 3.24279078 |
| 29 | Polyneuropathy (HP:0001271) | 3.19116733 |
| 30 | Keratoconjunctivitis sicca (HP:0001097) | 3.18567023 |
| 31 | IgM deficiency (HP:0002850) | 3.13919430 |
| 32 | Keratoconjunctivitis (HP:0001096) | 3.12265327 |
| 33 | Enlarged epiphyses (HP:0010580) | 3.08411021 |
| 34 | Recurrent viral infections (HP:0004429) | 3.06327021 |
| 35 | Combined immunodeficiency (HP:0005387) | 3.03875640 |
| 36 | Encephalitis (HP:0002383) | 2.97592109 |
| 37 | Thyroiditis (HP:0100646) | 2.96412740 |
| 38 | Hypoplasia of the thymus (HP:0000778) | 2.90953110 |
| 39 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.90875333 |
| 40 | Abnormality of the pleura (HP:0002103) | 2.89481182 |
| 41 | Gangrene (HP:0100758) | 2.84839453 |
| 42 | Lymphopenia (HP:0001888) | 2.81012744 |
| 43 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.80686532 |
| 44 | Hypochromic anemia (HP:0001931) | 2.75620651 |
| 45 | Granulocytopenia (HP:0001913) | 2.75210039 |
| 46 | Leukocytosis (HP:0001974) | 2.67971738 |
| 47 | Pulmonary embolism (HP:0002204) | 2.64525380 |
| 48 | Anorexia (HP:0002039) | 2.61671796 |
| 49 | Metaphyseal dysplasia (HP:0100255) | 2.61438108 |
| 50 | Keratitis (HP:0000491) | 2.60611167 |
| 51 | Eosinophilia (HP:0001880) | 2.57145356 |
| 52 | Abnormality of the prostate (HP:0008775) | 2.53029515 |
| 53 | Abnormality of T cell physiology (HP:0011840) | 2.50357471 |
| 54 | Autoimmune thrombocytopenia (HP:0001973) | 2.49064187 |
| 55 | 3-Methylglutaconic aciduria (HP:0003535) | 2.39707501 |
| 56 | Premature ovarian failure (HP:0008209) | 2.38224744 |
| 57 | Ureteral stenosis (HP:0000071) | 2.34033832 |
| 58 | Arterial thrombosis (HP:0004420) | 2.28773048 |
| 59 | Pustule (HP:0200039) | 2.27943812 |
| 60 | Ureteral obstruction (HP:0006000) | 2.24775945 |
| 61 | Renal cortical cysts (HP:0000803) | 2.22894262 |
| 62 | Chronic obstructive pulmonary disease (HP:0006510) | 2.22466946 |
| 63 | Obstructive lung disease (HP:0006536) | 2.22466946 |
| 64 | Gastrointestinal infarctions (HP:0005244) | 2.17728986 |
| 65 | Episodic fever (HP:0001954) | 2.17656622 |
| 66 | Porencephaly (HP:0002132) | 2.17068007 |
| 67 | Recurrent skin infections (HP:0001581) | 2.11074214 |
| 68 | Abnormality of the pericardium (HP:0001697) | 2.08805368 |
| 69 | Hypergammaglobulinemia (HP:0010702) | 2.07831426 |
| 70 | Prominent nose (HP:0000448) | 2.07291314 |
| 71 | Glomerulopathy (HP:0100820) | 2.06147876 |
| 72 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.06106608 |
| 73 | Exotropia (HP:0000577) | 2.04853014 |
| 74 | Arthropathy (HP:0003040) | 2.03348497 |
| 75 | Bronchitis (HP:0012387) | 2.03293864 |
| 76 | Mediastinal lymphadenopathy (HP:0100721) | 2.02685511 |
| 77 | Eczematoid dermatitis (HP:0000976) | 1.99697812 |
| 78 | Cerebral hypomyelination (HP:0006808) | 1.99632919 |
| 79 | Lymphoma (HP:0002665) | 1.97591620 |
| 80 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.97083122 |
| 81 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.97083122 |
| 82 | Abnormality of dental color (HP:0011073) | 1.92927703 |
| 83 | Clubbing of toes (HP:0100760) | 1.92303561 |
| 84 | Skin rash (HP:0000988) | 1.88199863 |
| 85 | Chest pain (HP:0100749) | 1.85720206 |
| 86 | Gastrointestinal stroma tumor (HP:0100723) | 1.83202651 |
| 87 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.78749952 |
| 88 | Glucose intolerance (HP:0000833) | 1.77307614 |
| 89 | Brushfield spots (HP:0001088) | 1.76697125 |
| 90 | Hepatosplenomegaly (HP:0001433) | 1.76226646 |
| 91 | Panhypogammaglobulinemia (HP:0003139) | 1.73376043 |
| 92 | Abnormal spermatogenesis (HP:0008669) | 1.70002680 |
| 93 | Squamous cell carcinoma (HP:0002860) | 1.69191675 |
| 94 | Neutropenia (HP:0001875) | 1.67618717 |
| 95 | Epistaxis (HP:0000421) | 1.67457505 |
| 96 | Paralysis (HP:0003470) | 1.63306976 |
| 97 | Urticaria (HP:0001025) | 1.62828678 |
| 98 | Abnormality of macrophages (HP:0004311) | 1.61367756 |
| 99 | Restrictive lung disease (HP:0002091) | 1.60458300 |
| 100 | Arterial tortuosity (HP:0005116) | 1.59879067 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK1 | 7.88846856 |
| 2 | TXK | 6.26943398 |
| 3 | VRK1 | 4.96832271 |
| 4 | PRPF4B | 3.41804213 |
| 5 | FES | 2.98839613 |
| 6 | PIK3CA | 2.84170493 |
| 7 | TYRO3 | 2.75950352 |
| 8 | IRAK3 | 2.33081090 |
| 9 | TAOK3 | 2.12058978 |
| 10 | CSK | 1.91870700 |
| 11 | MAP4K1 | 1.82955997 |
| 12 | TGFBR2 | 1.72383041 |
| 13 | ITK | 1.64568333 |
| 14 | BTK | 1.64283017 |
| 15 | SIK3 | 1.57559856 |
| 16 | MAP2K6 | 1.52369591 |
| 17 | TNIK | 1.43129908 |
| 18 | TRPM7 | 1.42997278 |
| 19 | CDK8 | 1.41347418 |
| 20 | NLK | 1.34848216 |
| 21 | JAK1 | 1.32317728 |
| 22 | FGFR4 | 1.30434403 |
| 23 | BMPR2 | 1.23961875 |
| 24 | LCK | 1.23029205 |
| 25 | MATK | 1.21632871 |
| 26 | TYK2 | 1.21155974 |
| 27 | MAPK11 | 1.16140624 |
| 28 | IKBKE | 1.15019458 |
| 29 | TEC | 1.10745902 |
| 30 | PLK3 | 1.09297586 |
| 31 | BCR | 1.09028606 |
| 32 | JAK3 | 1.07978921 |
| 33 | PRKCQ | 1.07619152 |
| 34 | HCK | 1.06354740 |
| 35 | TRIM28 | 1.03930898 |
| 36 | NTRK1 | 1.00422471 |
| 37 | PIM1 | 0.98084101 |
| 38 | TBK1 | 0.95997285 |
| 39 | CAMKK1 | 0.95500100 |
| 40 | MAP3K14 | 0.92359779 |
| 41 | PDGFRB | 0.92287917 |
| 42 | TLK1 | 0.91388383 |
| 43 | ADRBK2 | 0.91272632 |
| 44 | CAMKK2 | 0.90344625 |
| 45 | ACVR1B | 0.88308407 |
| 46 | SYK | 0.85935516 |
| 47 | LYN | 0.83154354 |
| 48 | RIPK4 | 0.77743333 |
| 49 | MELK | 0.76909521 |
| 50 | GRK6 | 0.75069475 |
| 51 | MAP4K2 | 0.74285037 |
| 52 | STK10 | 0.73916315 |
| 53 | JAK2 | 0.70926629 |
| 54 | IKBKB | 0.70840348 |
| 55 | PDK1 | 0.70754714 |
| 56 | TRIB3 | 0.69805769 |
| 57 | PRKCE | 0.68871926 |
| 58 | KDR | 0.68612518 |
| 59 | MARK3 | 0.67726758 |
| 60 | PKN2 | 0.66915910 |
| 61 | RET | 0.65049728 |
| 62 | KIT | 0.61801889 |
| 63 | MAPK7 | 0.57303487 |
| 64 | PDPK1 | 0.56998865 |
| 65 | PASK | 0.56938951 |
| 66 | CDK3 | 0.56410570 |
| 67 | FGFR3 | 0.55267319 |
| 68 | ZAP70 | 0.53002848 |
| 69 | LRRK2 | 0.46184290 |
| 70 | FYN | 0.42192715 |
| 71 | GRK7 | 0.42093447 |
| 72 | HIPK2 | 0.40256625 |
| 73 | CLK1 | 0.40078317 |
| 74 | PHKG2 | 0.37503609 |
| 75 | PHKG1 | 0.37503609 |
| 76 | IRAK4 | 0.36469693 |
| 77 | MAPKAPK2 | 0.34830597 |
| 78 | ZAK | 0.34485717 |
| 79 | BRD4 | 0.31338975 |
| 80 | MAPK13 | 0.31107633 |
| 81 | CHUK | 0.30543123 |
| 82 | IGF1R | 0.29904496 |
| 83 | MAP3K11 | 0.29090369 |
| 84 | NUAK1 | 0.28495827 |
| 85 | STK11 | 0.26105064 |
| 86 | BLK | 0.26038550 |
| 87 | IRAK1 | 0.25381355 |
| 88 | INSR | 0.22332260 |
| 89 | DYRK1A | 0.21228163 |
| 90 | EPHA3 | 0.19352044 |
| 91 | BMX | 0.17726340 |
| 92 | TNK2 | 0.17468680 |
| 93 | PRKACG | 0.17237544 |
| 94 | MAPK12 | 0.17148762 |
| 95 | MAPK3 | 0.15052438 |
| 96 | BUB1 | 0.14733496 |
| 97 | NME1 | 0.14294692 |
| 98 | BCKDK | 0.13878325 |
| 99 | CDK4 | 0.13863069 |
| 100 | PRKCB | 0.13463919 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.01194778 |
| 2 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.15104818 |
| 3 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.13921575 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.02414823 |
| 5 | Measles_Homo sapiens_hsa05162 | 2.87844416 |
| 6 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.85260889 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.83763000 |
| 8 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.61195495 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.46199584 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.40172222 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.39853627 |
| 12 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.23873909 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.20225898 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.94858633 |
| 15 | Hepatitis B_Homo sapiens_hsa05161 | 1.88393627 |
| 16 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.82294630 |
| 17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.81759945 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.80714039 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.72072442 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.71835542 |
| 21 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.69214118 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.50515421 |
| 23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.50028379 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.46870862 |
| 25 | Malaria_Homo sapiens_hsa05144 | 1.45315418 |
| 26 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.39567459 |
| 27 | Viral myocarditis_Homo sapiens_hsa05416 | 1.37044000 |
| 28 | Influenza A_Homo sapiens_hsa05164 | 1.35561847 |
| 29 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.32237789 |
| 30 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.31842773 |
| 31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.22237932 |
| 32 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.22041633 |
| 33 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.19406009 |
| 34 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.17285694 |
| 35 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.16164632 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.11550929 |
| 37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.08635777 |
| 38 | Leishmaniasis_Homo sapiens_hsa05140 | 1.04588459 |
| 39 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.04509209 |
| 40 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.99886961 |
| 41 | Salmonella infection_Homo sapiens_hsa05132 | 0.98467144 |
| 42 | Apoptosis_Homo sapiens_hsa04210 | 0.97510038 |
| 43 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.94931047 |
| 44 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.91721223 |
| 45 | Proteasome_Homo sapiens_hsa03050 | 0.89853293 |
| 46 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.89255262 |
| 47 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.87252380 |
| 48 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.86736802 |
| 49 | HTLV-I infection_Homo sapiens_hsa05166 | 0.86010643 |
| 50 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.81070065 |
| 51 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.79597634 |
| 52 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.78724773 |
| 53 | Shigellosis_Homo sapiens_hsa05131 | 0.76637467 |
| 54 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75267822 |
| 55 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.75211427 |
| 56 | Tuberculosis_Homo sapiens_hsa05152 | 0.72000397 |
| 57 | Cocaine addiction_Homo sapiens_hsa05030 | 0.71909687 |
| 58 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71683107 |
| 59 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.69828302 |
| 60 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.68649614 |
| 61 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68376404 |
| 62 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68077156 |
| 63 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66258747 |
| 64 | Asthma_Homo sapiens_hsa05310 | 0.65877151 |
| 65 | Platelet activation_Homo sapiens_hsa04611 | 0.62785761 |
| 66 | Hepatitis C_Homo sapiens_hsa05160 | 0.61000448 |
| 67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60856470 |
| 68 | Insulin resistance_Homo sapiens_hsa04931 | 0.59224553 |
| 69 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.58937961 |
| 70 | Prion diseases_Homo sapiens_hsa05020 | 0.57910091 |
| 71 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.57743682 |
| 72 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.53175132 |
| 73 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.50013586 |
| 74 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.46519446 |
| 75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.44388700 |
| 76 | Thyroid cancer_Homo sapiens_hsa05216 | 0.43648887 |
| 77 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.43068567 |
| 78 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40428403 |
| 79 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.39772665 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.39369471 |
| 81 | Endocytosis_Homo sapiens_hsa04144 | 0.37422896 |
| 82 | Pertussis_Homo sapiens_hsa05133 | 0.36426756 |
| 83 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.34985347 |
| 84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.34507146 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33223996 |
| 86 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.31166799 |
| 87 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.29574187 |
| 88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29224103 |
| 89 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.29065223 |
| 90 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.28995282 |
| 91 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28466986 |
| 92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.27423165 |
| 93 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.26476821 |
| 94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.22682650 |
| 95 | Insulin secretion_Homo sapiens_hsa04911 | 0.21385324 |
| 96 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.20206898 |
| 97 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.19377268 |
| 98 | Olfactory transduction_Homo sapiens_hsa04740 | 0.19259781 |
| 99 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.18472483 |
| 100 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.16908034 |

