

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of growth hormone secretion (GO:0060124) | 8.56505749 |
| 2 | growth hormone secretion (GO:0030252) | 7.86261904 |
| 3 | NIK/NF-kappaB signaling (GO:0038061) | 7.65302545 |
| 4 | natural killer cell differentiation (GO:0001779) | 6.65165171 |
| 5 | determination of adult lifespan (GO:0008340) | 6.42971720 |
| 6 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.96462561 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.80302918 |
| 8 | negative T cell selection (GO:0043383) | 5.74767973 |
| 9 | regulation of growth hormone secretion (GO:0060123) | 5.65436343 |
| 10 | negative thymic T cell selection (GO:0045060) | 5.64996090 |
| 11 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.06193389 |
| 12 | negative regulation of cell killing (GO:0031342) | 4.98976336 |
| 13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.98976336 |
| 14 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 4.97861605 |
| 15 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 4.86261616 |
| 16 | positive thymic T cell selection (GO:0045059) | 4.72400849 |
| 17 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.62980651 |
| 18 | nucleoside diphosphate catabolic process (GO:0009134) | 4.61544648 |
| 19 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.61385272 |
| 20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.59512144 |
| 21 | positive T cell selection (GO:0043368) | 4.58511474 |
| 22 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.57955356 |
| 23 | thymic T cell selection (GO:0045061) | 4.55227156 |
| 24 | negative regulation of phagocytosis (GO:0050765) | 4.49686154 |
| 25 | regulation of RIG-I signaling pathway (GO:0039535) | 4.47514790 |
| 26 | regulation of T cell tolerance induction (GO:0002664) | 4.30638450 |
| 27 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.21561681 |
| 28 | T cell selection (GO:0045058) | 4.13732335 |
| 29 | female mating behavior (GO:0060180) | 4.10758062 |
| 30 | regulation of female receptivity (GO:0045924) | 4.09283725 |
| 31 | regulation of gamma-delta T cell activation (GO:0046643) | 4.07418963 |
| 32 | positive regulation of tolerance induction (GO:0002645) | 4.03343774 |
| 33 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.98369169 |
| 34 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.94597018 |
| 35 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.93755964 |
| 36 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.91186988 |
| 37 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.91186988 |
| 38 | regulation of G0 to G1 transition (GO:0070316) | 3.87856747 |
| 39 | T cell receptor signaling pathway (GO:0050852) | 3.86464813 |
| 40 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.84423805 |
| 41 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.81969637 |
| 42 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.76365153 |
| 43 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.75958878 |
| 44 | Peyers patch development (GO:0048541) | 3.75958878 |
| 45 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.75738857 |
| 46 | actin nucleation (GO:0045010) | 3.75688105 |
| 47 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.75071540 |
| 48 | positive regulation of granulocyte differentiation (GO:0030854) | 3.73925137 |
| 49 | response to UV-C (GO:0010225) | 3.70668268 |
| 50 | autophagic vacuole fusion (GO:0000046) | 3.66279292 |
| 51 | glomerular visceral epithelial cell development (GO:0072015) | 3.65635728 |
| 52 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.62980082 |
| 53 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.60049931 |
| 54 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.59680385 |
| 55 | regulation of tolerance induction (GO:0002643) | 3.59013307 |
| 56 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.59006608 |
| 57 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.58817490 |
| 58 | coenzyme catabolic process (GO:0009109) | 3.57917535 |
| 59 | regulation of regulatory T cell differentiation (GO:0045589) | 3.57760376 |
| 60 | lymph node development (GO:0048535) | 3.52966787 |
| 61 | cellular response to interleukin-15 (GO:0071350) | 3.49666318 |
| 62 | activated T cell proliferation (GO:0050798) | 3.46154895 |
| 63 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.45035894 |
| 64 | negative regulation of T cell mediated immunity (GO:0002710) | 3.43309792 |
| 65 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.42704983 |
| 66 | response to interleukin-15 (GO:0070672) | 3.40327817 |
| 67 | activation of adenylate cyclase activity (GO:0007190) | 3.40265970 |
| 68 | regulation of necroptotic process (GO:0060544) | 3.39881066 |
| 69 | natural killer cell activation (GO:0030101) | 3.37032716 |
| 70 | negative regulation of Ras GTPase activity (GO:0034261) | 3.33738352 |
| 71 | regulation of cell killing (GO:0031341) | 3.33301888 |
| 72 | regulation of metalloenzyme activity (GO:0048552) | 3.33145343 |
| 73 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.32886853 |
| 74 | tolerance induction (GO:0002507) | 3.31589640 |
| 75 | respiratory burst (GO:0045730) | 3.31127120 |
| 76 | I-kappaB phosphorylation (GO:0007252) | 3.27907817 |
| 77 | T cell migration (GO:0072678) | 3.27498131 |
| 78 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.26467300 |
| 79 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 3.24225836 |
| 80 | positive regulation of cell killing (GO:0031343) | 3.21880189 |
| 81 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.21137580 |
| 82 | glomerular epithelial cell development (GO:0072310) | 3.19408999 |
| 83 | regulation of protein heterodimerization activity (GO:0043497) | 3.14642412 |
| 84 | regulation of antigen processing and presentation (GO:0002577) | 3.12524381 |
| 85 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.11390868 |
| 86 | adaptation of signaling pathway (GO:0023058) | 3.11114583 |
| 87 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.08328067 |
| 88 | negative regulation of telomere maintenance (GO:0032205) | 3.08138822 |
| 89 | regulation of B cell differentiation (GO:0045577) | 3.05807309 |
| 90 | positive regulation of B cell differentiation (GO:0045579) | 3.02251491 |
| 91 | neutrophil activation involved in immune response (GO:0002283) | 3.01206581 |
| 92 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.00705209 |
| 93 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.00705209 |
| 94 | modulation by symbiont of host immune response (GO:0052553) | 3.00705209 |
| 95 | positive regulation by symbiont of host defense response (GO:0052509) | 3.00705209 |
| 96 | modulation by symbiont of host defense response (GO:0052031) | 3.00705209 |
| 97 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.00705209 |
| 98 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.99073856 |
| 99 | type I interferon signaling pathway (GO:0060337) | 2.98743385 |
| 100 | cellular response to type I interferon (GO:0071357) | 2.98743385 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.74322700 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.66462343 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.56879736 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 5.17017520 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.06008340 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.59652563 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.42956349 |
| 8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.42186151 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.11790270 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.02934255 |
| 11 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.93311937 |
| 12 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.88647826 |
| 13 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.81423486 |
| 14 | UTX_26944678_Chip-Seq_JUKART_Human | 2.74813778 |
| 15 | MAF_26560356_Chip-Seq_TH1_Human | 2.61688946 |
| 16 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.61438254 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.58946803 |
| 18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.48612991 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.43643185 |
| 20 | MAF_26560356_Chip-Seq_TH2_Human | 2.28197766 |
| 21 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.25133014 |
| 22 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.21882853 |
| 23 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.20176739 |
| 24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.12568624 |
| 25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.11585728 |
| 26 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.00699317 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.98954206 |
| 28 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.89269467 |
| 29 | MYC_22102868_ChIP-Seq_BL_Human | 1.85584184 |
| 30 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.78600353 |
| 31 | GATA3_26560356_Chip-Seq_TH2_Human | 1.74660495 |
| 32 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.72765314 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70768003 |
| 34 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.68076737 |
| 35 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60407067 |
| 36 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.59615348 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.57235987 |
| 38 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.53409444 |
| 39 | SPI1_23127762_ChIP-Seq_K562_Human | 1.50611636 |
| 40 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.50392587 |
| 41 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.50041187 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47915563 |
| 43 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.44978370 |
| 44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.41471161 |
| 45 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.39382478 |
| 46 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 1.38353148 |
| 47 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.38156222 |
| 48 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.36125331 |
| 49 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.31662345 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.25655439 |
| 51 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.17063854 |
| 52 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.16994040 |
| 53 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.16208341 |
| 54 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.14993157 |
| 55 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.13898168 |
| 56 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.12185641 |
| 57 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.11811688 |
| 58 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.09926472 |
| 59 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.08774045 |
| 60 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07590060 |
| 61 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.07492302 |
| 62 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06218080 |
| 63 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.02932210 |
| 64 | SA1_27219007_Chip-Seq_Bcells_Human | 1.02005938 |
| 65 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01203819 |
| 66 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.00309431 |
| 67 | GATA1_19941826_ChIP-Seq_K562_Human | 0.99482411 |
| 68 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.99418827 |
| 69 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.98643129 |
| 70 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.97761855 |
| 71 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.97366443 |
| 72 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96778463 |
| 73 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95700066 |
| 74 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.94615907 |
| 75 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.94157870 |
| 76 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.93861868 |
| 77 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.93819219 |
| 78 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.93107754 |
| 79 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92243506 |
| 80 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92153074 |
| 81 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.91714337 |
| 82 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91284376 |
| 83 | P300_27268052_Chip-Seq_Bcells_Human | 0.91118433 |
| 84 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90684069 |
| 85 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.90527874 |
| 86 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89609134 |
| 87 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88879844 |
| 88 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.88759790 |
| 89 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.88387925 |
| 90 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.85204066 |
| 91 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.84735087 |
| 92 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.83586086 |
| 93 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.82595682 |
| 94 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.82557413 |
| 95 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.81412299 |
| 96 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.81187929 |
| 97 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.80595679 |
| 98 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.80181032 |
| 99 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.79640955 |
| 100 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.78712247 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.60627703 |
| 2 | MP0003763_abnormal_thymus_physiology | 4.37195326 |
| 3 | MP0001501_abnormal_sleep_pattern | 3.54673918 |
| 4 | MP0001800_abnormal_humoral_immune | 3.04001339 |
| 5 | MP0002909_abnormal_adrenal_gland | 3.00350668 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 2.81872113 |
| 7 | MP0000015_abnormal_ear_pigmentation | 2.81253362 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.75877302 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.67644090 |
| 10 | MP0002277_abnormal_respiratory_mucosa | 2.65130931 |
| 11 | MP0003436_decreased_susceptibility_to | 2.63634100 |
| 12 | MP0005025_abnormal_response_to | 2.63381839 |
| 13 | MP0002723_abnormal_immune_serum | 2.63341407 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.54155710 |
| 15 | MP0003866_abnormal_defecation | 2.52329925 |
| 16 | MP0001819_abnormal_immune_cell | 2.50231225 |
| 17 | MP0000685_abnormal_immune_system | 2.42976447 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.37932358 |
| 19 | MP0009785_altered_susceptibility_to | 2.37028994 |
| 20 | MP0004381_abnormal_hair_follicle | 2.35244120 |
| 21 | MP0005387_immune_system_phenotype | 2.31095277 |
| 22 | MP0001790_abnormal_immune_system | 2.31095277 |
| 23 | MP0002405_respiratory_system_inflammati | 2.30289286 |
| 24 | MP0002398_abnormal_bone_marrow | 2.14986623 |
| 25 | MP0003724_increased_susceptibility_to | 2.09845494 |
| 26 | MP0000716_abnormal_immune_system | 2.05175125 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 2.02911539 |
| 28 | MP0002419_abnormal_innate_immunity | 2.02083064 |
| 29 | MP0002132_abnormal_respiratory_system | 1.98809476 |
| 30 | MP0001881_abnormal_mammary_gland | 1.94549145 |
| 31 | MP0000703_abnormal_thymus_morphology | 1.89027865 |
| 32 | MP0003787_abnormal_imprinting | 1.87106896 |
| 33 | MP0002102_abnormal_ear_morphology | 1.71256023 |
| 34 | MP0010155_abnormal_intestine_physiology | 1.71184154 |
| 35 | MP0000689_abnormal_spleen_morphology | 1.69713386 |
| 36 | MP0002933_joint_inflammation | 1.66608829 |
| 37 | MP0002166_altered_tumor_susceptibility | 1.59931658 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.59712943 |
| 39 | MP0002722_abnormal_immune_system | 1.58106731 |
| 40 | MP0002429_abnormal_blood_cell | 1.56542108 |
| 41 | MP0001873_stomach_inflammation | 1.55632318 |
| 42 | MP0004947_skin_inflammation | 1.52774546 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.49984703 |
| 44 | MP0003303_peritoneal_inflammation | 1.47981894 |
| 45 | MP0001533_abnormal_skeleton_physiology | 1.47309795 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.42876571 |
| 47 | MP0003786_premature_aging | 1.37347412 |
| 48 | MP0003959_abnormal_lean_body | 1.33268732 |
| 49 | MP0005266_abnormal_metabolism | 1.30093363 |
| 50 | MP0006082_CNS_inflammation | 1.29071477 |
| 51 | MP0008260_abnormal_autophagy | 1.28849338 |
| 52 | MP0006276_abnormal_autonomic_nervous | 1.27505971 |
| 53 | MP0001851_eye_inflammation | 1.25712488 |
| 54 | MP0003172_abnormal_lysosome_physiology | 1.25053958 |
| 55 | MP0008469_abnormal_protein_level | 1.19744327 |
| 56 | MP0002396_abnormal_hematopoietic_system | 1.15921131 |
| 57 | MP0003183_abnormal_peptide_metabolism | 1.15365781 |
| 58 | MP0002254_reproductive_system_inflammat | 1.12099632 |
| 59 | MP0003300_gastrointestinal_ulcer | 1.10783773 |
| 60 | MP0008961_abnormal_basal_metabolism | 1.10763064 |
| 61 | MP0000465_gastrointestinal_hemorrhage | 1.07839837 |
| 62 | MP0001853_heart_inflammation | 1.05098447 |
| 63 | MP0008872_abnormal_physiological_respon | 1.01537740 |
| 64 | MP0002006_tumorigenesis | 1.00580539 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 0.99981208 |
| 66 | MP0001348_abnormal_lacrimal_gland | 0.97919216 |
| 67 | MP0002136_abnormal_kidney_physiology | 0.96754928 |
| 68 | MP0002095_abnormal_skin_pigmentation | 0.94188643 |
| 69 | MP0008058_abnormal_DNA_repair | 0.91131219 |
| 70 | MP0009278_abnormal_bone_marrow | 0.91038287 |
| 71 | MP0000920_abnormal_myelination | 0.89937101 |
| 72 | MP0000230_abnormal_systemic_arterial | 0.89387750 |
| 73 | MP0008877_abnormal_DNA_methylation | 0.88720518 |
| 74 | MP0003795_abnormal_bone_structure | 0.87459768 |
| 75 | MP0009764_decreased_sensitivity_to | 0.85505716 |
| 76 | MP0000490_abnormal_crypts_of | 0.84521901 |
| 77 | MP0005451_abnormal_body_composition | 0.84166198 |
| 78 | MP0005248_abnormal_Harderian_gland | 0.83887410 |
| 79 | MP0002019_abnormal_tumor_incidence | 0.83463388 |
| 80 | MP0005174_abnormal_tail_pigmentation | 0.83005313 |
| 81 | MP0002138_abnormal_hepatobiliary_system | 0.82516392 |
| 82 | MP0000858_altered_metastatic_potential | 0.81277693 |
| 83 | MP0005164_abnormal_response_to | 0.79293108 |
| 84 | MP0009384_cardiac_valve_regurgitation | 0.79024064 |
| 85 | MP0002998_abnormal_bone_remodeling | 0.73445612 |
| 86 | MP0002693_abnormal_pancreas_physiology | 0.71936390 |
| 87 | MP0006036_abnormal_mitochondrial_physio | 0.68984491 |
| 88 | MP0005376_homeostasis/metabolism_phenot | 0.67789777 |
| 89 | MP0004883_abnormal_blood_vessel | 0.67199968 |
| 90 | MP0002163_abnormal_gland_morphology | 0.66141616 |
| 91 | MP0009643_abnormal_urine_homeostasis | 0.63576706 |
| 92 | MP0008995_early_reproductive_senescence | 0.63440017 |
| 93 | MP0001119_abnormal_female_reproductive | 0.60552926 |
| 94 | MP0003806_abnormal_nucleotide_metabolis | 0.60299007 |
| 95 | MP0008873_increased_physiological_sensi | 0.59167854 |
| 96 | MP0003075_altered_response_to | 0.58242130 |
| 97 | MP0008874_decreased_physiological_sensi | 0.57549309 |
| 98 | MP0001663_abnormal_digestive_system | 0.53995554 |
| 99 | MP0002168_other_aberrant_phenotype | 0.52612911 |
| 100 | MP0005310_abnormal_salivary_gland | 0.51844472 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sensory axonal neuropathy (HP:0003390) | 7.80646174 |
| 2 | Severe visual impairment (HP:0001141) | 5.76971692 |
| 3 | Slow saccadic eye movements (HP:0000514) | 5.69382387 |
| 4 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.44773224 |
| 5 | Keratoconjunctivitis sicca (HP:0001097) | 5.04943985 |
| 6 | T lymphocytopenia (HP:0005403) | 4.87383795 |
| 7 | Cerebral hypomyelination (HP:0006808) | 4.67680684 |
| 8 | Keratoconjunctivitis (HP:0001096) | 4.64994129 |
| 9 | Abnormality of T cell number (HP:0011839) | 4.27219215 |
| 10 | Recurrent skin infections (HP:0001581) | 4.16088618 |
| 11 | Spastic paraparesis (HP:0002313) | 3.90588143 |
| 12 | Stomatitis (HP:0010280) | 3.80010329 |
| 13 | Prostate neoplasm (HP:0100787) | 3.65248428 |
| 14 | Pustule (HP:0200039) | 3.62443469 |
| 15 | Aplastic anemia (HP:0001915) | 3.58284069 |
| 16 | Myositis (HP:0100614) | 3.53763723 |
| 17 | Palpebral edema (HP:0100540) | 3.52946328 |
| 18 | Severe combined immunodeficiency (HP:0004430) | 3.44115948 |
| 19 | Tubulointerstitial fibrosis (HP:0005576) | 3.37880073 |
| 20 | Eczematoid dermatitis (HP:0000976) | 3.29902690 |
| 21 | Retinal atrophy (HP:0001105) | 3.29380117 |
| 22 | IgG deficiency (HP:0004315) | 3.28132530 |
| 23 | Keratitis (HP:0000491) | 3.26930429 |
| 24 | Abnormality of T cells (HP:0002843) | 3.17064888 |
| 25 | Recurrent bacterial skin infections (HP:0005406) | 3.15942629 |
| 26 | Cellulitis (HP:0100658) | 3.15116189 |
| 27 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.09442483 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.09442483 |
| 29 | Poor speech (HP:0002465) | 3.04369250 |
| 30 | Recurrent abscess formation (HP:0002722) | 3.02020371 |
| 31 | Chronic diarrhea (HP:0002028) | 2.95411413 |
| 32 | Pigmentary retinal degeneration (HP:0001146) | 2.92356553 |
| 33 | Increased IgM level (HP:0003496) | 2.88693745 |
| 34 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.87636446 |
| 35 | Single umbilical artery (HP:0001195) | 2.87636446 |
| 36 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.87636446 |
| 37 | CNS hypomyelination (HP:0003429) | 2.84084077 |
| 38 | Abnormality of the prostate (HP:0008775) | 2.83849137 |
| 39 | Spontaneous hematomas (HP:0007420) | 2.83570822 |
| 40 | Encephalitis (HP:0002383) | 2.78427604 |
| 41 | Recurrent fungal infections (HP:0002841) | 2.77113343 |
| 42 | Growth hormone deficiency (HP:0000824) | 2.73111740 |
| 43 | Acute hepatic failure (HP:0006554) | 2.67817218 |
| 44 | Amblyopia (HP:0000646) | 2.64661134 |
| 45 | Combined immunodeficiency (HP:0005387) | 2.61717057 |
| 46 | Meningitis (HP:0001287) | 2.61356936 |
| 47 | Episodic fever (HP:0001954) | 2.55789273 |
| 48 | Optic neuritis (HP:0100653) | 2.55558425 |
| 49 | Retrobulbar optic neuritis (HP:0100654) | 2.55558425 |
| 50 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.50047279 |
| 51 | Mediastinal lymphadenopathy (HP:0100721) | 2.49849542 |
| 52 | Orchitis (HP:0100796) | 2.48804299 |
| 53 | Tubular atrophy (HP:0000092) | 2.48301573 |
| 54 | Autoimmune hemolytic anemia (HP:0001890) | 2.44858714 |
| 55 | Recurrent corneal erosions (HP:0000495) | 2.34197849 |
| 56 | Hypoalbuminemia (HP:0003073) | 2.30239699 |
| 57 | Abnormal albumin level (HP:0012116) | 2.30239699 |
| 58 | Increased intramyocellular lipid droplets (HP:0012240) | 2.27858170 |
| 59 | Increased cerebral lipofuscin (HP:0011813) | 2.27767754 |
| 60 | Verrucae (HP:0200043) | 2.27716371 |
| 61 | Papilloma (HP:0012740) | 2.27716371 |
| 62 | Increased muscle lipid content (HP:0009058) | 2.25808261 |
| 63 | Lymphopenia (HP:0001888) | 2.25068506 |
| 64 | Obstructive lung disease (HP:0006536) | 2.23541999 |
| 65 | Chronic obstructive pulmonary disease (HP:0006510) | 2.23541999 |
| 66 | Vasculitis (HP:0002633) | 2.23343273 |
| 67 | IgM deficiency (HP:0002850) | 2.23143098 |
| 68 | Intention tremor (HP:0002080) | 2.23139223 |
| 69 | Oral leukoplakia (HP:0002745) | 2.22242891 |
| 70 | Hypoplastic left heart (HP:0004383) | 2.19408584 |
| 71 | Granulocytopenia (HP:0001913) | 2.19225181 |
| 72 | Gastrointestinal infarctions (HP:0005244) | 2.18604188 |
| 73 | Abnormal drinking behavior (HP:0030082) | 2.17348207 |
| 74 | Polydipsia (HP:0001959) | 2.17348207 |
| 75 | Agammaglobulinemia (HP:0004432) | 2.17175840 |
| 76 | Progressive visual loss (HP:0000529) | 2.16557276 |
| 77 | Abnormality of saccadic eye movements (HP:0000570) | 2.15813504 |
| 78 | Panhypogammaglobulinemia (HP:0003139) | 2.13858580 |
| 79 | Hepatocellular necrosis (HP:0001404) | 2.13030466 |
| 80 | Microvesicular hepatic steatosis (HP:0001414) | 2.11655204 |
| 81 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.10394207 |
| 82 | Abnormality of macrophages (HP:0004311) | 2.10119825 |
| 83 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.09670014 |
| 84 | Micronodular cirrhosis (HP:0001413) | 2.06063776 |
| 85 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.05769834 |
| 86 | Urticaria (HP:0001025) | 2.03507065 |
| 87 | Petechiae (HP:0000967) | 2.01977240 |
| 88 | Stage 5 chronic kidney disease (HP:0003774) | 2.01628473 |
| 89 | Leukocytosis (HP:0001974) | 2.00684637 |
| 90 | Prolonged bleeding time (HP:0003010) | 1.99931771 |
| 91 | Cellular immunodeficiency (HP:0005374) | 1.99750303 |
| 92 | Paraparesis (HP:0002385) | 1.98238926 |
| 93 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.97524961 |
| 94 | Abnormality of eosinophils (HP:0001879) | 1.95576435 |
| 95 | Mask-like facies (HP:0000298) | 1.95046884 |
| 96 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.94125714 |
| 97 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92087865 |
| 98 | Complete atrioventricular canal defect (HP:0001674) | 1.89982571 |
| 99 | Tubulointerstitial abnormality (HP:0001969) | 1.89748886 |
| 100 | Abnormal number of erythroid precursors (HP:0012131) | 1.88499774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.97884285 |
| 2 | TESK2 | 4.80587290 |
| 3 | TXK | 4.27818764 |
| 4 | MAP3K6 | 3.68866032 |
| 5 | CAMKK2 | 3.15676453 |
| 6 | BCKDK | 3.12151523 |
| 7 | KDR | 3.09309865 |
| 8 | IRAK4 | 3.07548928 |
| 9 | MAP3K12 | 3.04236150 |
| 10 | IKBKE | 2.87783656 |
| 11 | DAPK1 | 2.39679442 |
| 12 | CDK19 | 2.31132481 |
| 13 | ZAP70 | 2.23106803 |
| 14 | GRK6 | 2.13687383 |
| 15 | TESK1 | 2.01966661 |
| 16 | VRK2 | 2.01482625 |
| 17 | MAP3K4 | 1.94154575 |
| 18 | ITK | 1.90681621 |
| 19 | TAOK3 | 1.78916739 |
| 20 | MAPKAPK3 | 1.67433194 |
| 21 | SYK | 1.66772233 |
| 22 | BMX | 1.66467708 |
| 23 | FES | 1.66432782 |
| 24 | TYK2 | 1.60503904 |
| 25 | RPS6KA4 | 1.49359093 |
| 26 | CSK | 1.44976207 |
| 27 | BTK | 1.43390754 |
| 28 | CAMKK1 | 1.42110244 |
| 29 | LCK | 1.39993285 |
| 30 | SIK3 | 1.30515392 |
| 31 | MYLK | 1.15113625 |
| 32 | HCK | 1.13272978 |
| 33 | LIMK1 | 1.11482274 |
| 34 | PASK | 1.08334919 |
| 35 | CSF1R | 1.00416482 |
| 36 | JAK3 | 0.98272483 |
| 37 | VRK1 | 0.97434509 |
| 38 | TEC | 0.92119133 |
| 39 | TNK2 | 0.86716426 |
| 40 | RIPK4 | 0.85393213 |
| 41 | MARK3 | 0.85205542 |
| 42 | LYN | 0.81300470 |
| 43 | SIK2 | 0.80410739 |
| 44 | PRKCH | 0.73149690 |
| 45 | CDK12 | 0.73011709 |
| 46 | PRKD3 | 0.72795792 |
| 47 | MAP3K14 | 0.72159281 |
| 48 | IKBKB | 0.70412076 |
| 49 | BLK | 0.70396872 |
| 50 | PRKCQ | 0.65701360 |
| 51 | MAP3K11 | 0.64419227 |
| 52 | BRSK2 | 0.63812679 |
| 53 | KIT | 0.60370252 |
| 54 | ERN1 | 0.59001761 |
| 55 | PRPF4B | 0.58692975 |
| 56 | MAPKAPK2 | 0.56986088 |
| 57 | NME1 | 0.55813638 |
| 58 | DDR2 | 0.54782135 |
| 59 | LRRK2 | 0.51982896 |
| 60 | FYN | 0.51796534 |
| 61 | JAK1 | 0.50553569 |
| 62 | MAP3K1 | 0.45761349 |
| 63 | TBK1 | 0.44731426 |
| 64 | BRD4 | 0.43557771 |
| 65 | HIPK2 | 0.43543786 |
| 66 | CAMK1 | 0.43198376 |
| 67 | JAK2 | 0.39174165 |
| 68 | CLK1 | 0.38687967 |
| 69 | ERBB3 | 0.37704612 |
| 70 | PIM1 | 0.37014797 |
| 71 | MST4 | 0.36587113 |
| 72 | EPHA3 | 0.36550378 |
| 73 | NLK | 0.34737820 |
| 74 | TAOK1 | 0.31342284 |
| 75 | STK11 | 0.31179271 |
| 76 | PDK1 | 0.29647294 |
| 77 | STK4 | 0.29397318 |
| 78 | EPHB1 | 0.29206459 |
| 79 | TRPM7 | 0.27151571 |
| 80 | MAPK4 | 0.26409598 |
| 81 | CDK4 | 0.24504003 |
| 82 | INSR | 0.23941340 |
| 83 | MAPK7 | 0.23926084 |
| 84 | MAP3K3 | 0.23653837 |
| 85 | PAK4 | 0.23310179 |
| 86 | MAPK12 | 0.23302599 |
| 87 | SMG1 | 0.23061183 |
| 88 | PDGFRB | 0.22511522 |
| 89 | STK10 | 0.21732639 |
| 90 | IGF1R | 0.21257883 |
| 91 | CHUK | 0.20762535 |
| 92 | KSR2 | 0.20701270 |
| 93 | CAMK2B | 0.20336457 |
| 94 | NEK6 | 0.18493558 |
| 95 | PRKD1 | 0.18375476 |
| 96 | RPS6KA5 | 0.18361671 |
| 97 | PRKCB | 0.18290393 |
| 98 | MAPK11 | 0.18253448 |
| 99 | PRKAA1 | 0.17941546 |
| 100 | MAPK3 | 0.16896677 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.35128258 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.24494518 |
| 3 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.10811942 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00412774 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.99219123 |
| 6 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.84884293 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.72008580 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.70427689 |
| 9 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.69295362 |
| 10 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.62307374 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.60439936 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.38565877 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.14506201 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.98842115 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.88426682 |
| 16 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.88100946 |
| 17 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.76053521 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.69068365 |
| 19 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.68385230 |
| 20 | Sulfur relay system_Homo sapiens_hsa04122 | 1.67123284 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.64670700 |
| 22 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.61203397 |
| 23 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.57469248 |
| 24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.47001080 |
| 25 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.44914172 |
| 26 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.41236161 |
| 27 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.39601954 |
| 28 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.37860310 |
| 29 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.27370818 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.21573749 |
| 31 | Proteasome_Homo sapiens_hsa03050 | 1.20122355 |
| 32 | Circadian rhythm_Homo sapiens_hsa04710 | 1.20105825 |
| 33 | Shigellosis_Homo sapiens_hsa05131 | 1.14474215 |
| 34 | Ribosome_Homo sapiens_hsa03010 | 1.10837238 |
| 35 | Asthma_Homo sapiens_hsa05310 | 1.09690241 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.07991050 |
| 37 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.04137028 |
| 38 | Tuberculosis_Homo sapiens_hsa05152 | 1.03934674 |
| 39 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.03294669 |
| 40 | Influenza A_Homo sapiens_hsa05164 | 1.03267993 |
| 41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.93425569 |
| 42 | Legionellosis_Homo sapiens_hsa05134 | 0.93173593 |
| 43 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.90023068 |
| 44 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.88401546 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.85245452 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.82984296 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82621486 |
| 48 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.81894854 |
| 49 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.81763265 |
| 50 | Salmonella infection_Homo sapiens_hsa05132 | 0.81695401 |
| 51 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.80717498 |
| 52 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.80559493 |
| 53 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.79684547 |
| 54 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.72165103 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71343906 |
| 56 | Hepatitis C_Homo sapiens_hsa05160 | 0.71282574 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70626299 |
| 58 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.70260229 |
| 59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.70061758 |
| 60 | Platelet activation_Homo sapiens_hsa04611 | 0.69418000 |
| 61 | Parkinsons disease_Homo sapiens_hsa05012 | 0.65345262 |
| 62 | HTLV-I infection_Homo sapiens_hsa05166 | 0.64832482 |
| 63 | Base excision repair_Homo sapiens_hsa03410 | 0.64564052 |
| 64 | Endocytosis_Homo sapiens_hsa04144 | 0.62998116 |
| 65 | Phagosome_Homo sapiens_hsa04145 | 0.61070912 |
| 66 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.58661429 |
| 67 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.57516762 |
| 68 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.57107122 |
| 69 | Pertussis_Homo sapiens_hsa05133 | 0.54318245 |
| 70 | Apoptosis_Homo sapiens_hsa04210 | 0.52636069 |
| 71 | Huntingtons disease_Homo sapiens_hsa05016 | 0.51573337 |
| 72 | RNA degradation_Homo sapiens_hsa03018 | 0.51194515 |
| 73 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49773812 |
| 74 | RNA polymerase_Homo sapiens_hsa03020 | 0.49652523 |
| 75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.47368597 |
| 76 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.45786102 |
| 77 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.44909483 |
| 78 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.44505614 |
| 79 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43766216 |
| 80 | Hepatitis B_Homo sapiens_hsa05161 | 0.42430945 |
| 81 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.41586191 |
| 82 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.40485886 |
| 83 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39641572 |
| 84 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.35736720 |
| 85 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.35090793 |
| 86 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.32662173 |
| 87 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.31840879 |
| 88 | Purine metabolism_Homo sapiens_hsa00230 | 0.29316591 |
| 89 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.28449085 |
| 90 | Histidine metabolism_Homo sapiens_hsa00340 | 0.28360297 |
| 91 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.28192504 |
| 92 | Alzheimers disease_Homo sapiens_hsa05010 | 0.26148804 |
| 93 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.25627057 |
| 94 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.24693898 |
| 95 | Homologous recombination_Homo sapiens_hsa03440 | 0.22240770 |
| 96 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.20670059 |
| 97 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.20322796 |
| 98 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.19549731 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.18787985 |
| 100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.13960074 |

