TRBV29-1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)7.19304948
2negative thymic T cell selection (GO:0045060)6.78317267
3positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.57566781
4negative regulation of cell killing (GO:0031342)6.48673697
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.48673697
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.42553230
7positive regulation of gamma-delta T cell activation (GO:0046645)6.11686612
8tolerance induction (GO:0002507)5.86679847
9positive T cell selection (GO:0043368)5.81622671
10thymic T cell selection (GO:0045061)5.77315872
11positive thymic T cell selection (GO:0045059)5.72885758
12antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.54007146
13T cell selection (GO:0045058)5.44096109
14positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.27800260
15regulation of gamma-delta T cell differentiation (GO:0045586)5.24874849
16antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.09859608
17antigen processing and presentation of endogenous antigen (GO:0019883)5.03297968
18regulation of T cell tolerance induction (GO:0002664)5.02421580
19regulation of B cell receptor signaling pathway (GO:0050855)4.98385177
20response to interleukin-15 (GO:0070672)4.95910341
21regulation of gamma-delta T cell activation (GO:0046643)4.88014531
22leukocyte aggregation (GO:0070486)4.80925978
23cellular response to interleukin-15 (GO:0071350)4.67618720
24T cell migration (GO:0072678)4.60761237
25Peyers patch development (GO:0048541)4.60738404
26mucosal-associated lymphoid tissue development (GO:0048537)4.60738404
27positive regulation of tolerance induction (GO:0002645)4.57495038
28regulation of alpha-beta T cell proliferation (GO:0046640)4.43902949
29regulation of regulatory T cell differentiation (GO:0045589)4.42809392
30regulation of tolerance induction (GO:0002643)4.38971126
31negative regulation of T cell mediated immunity (GO:0002710)4.32869264
32activated T cell proliferation (GO:0050798)4.32869238
33regulation of isotype switching to IgG isotypes (GO:0048302)4.25542335
34negative regulation of lymphocyte mediated immunity (GO:0002707)4.01747206
35interferon-gamma production (GO:0032609)4.01462923
36positive regulation of alpha-beta T cell proliferation (GO:0046641)3.94210312
37regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.90718851
38regulation of natural killer cell mediated immunity (GO:0002715)3.90718851
39regulation of interleukin-2 biosynthetic process (GO:0045076)3.89821561
40regulation of B cell differentiation (GO:0045577)3.81965075
41positive regulation of granulocyte differentiation (GO:0030854)3.77445684
42respiratory burst (GO:0045730)3.77439620
43regulation of T cell mediated cytotoxicity (GO:0001914)3.75156742
44T cell receptor signaling pathway (GO:0050852)3.74644614
45positive regulation of natural killer cell differentiation (GO:0032825)3.72355282
46positive regulation of T cell mediated cytotoxicity (GO:0001916)3.69102134
47positive regulation of T cell differentiation in thymus (GO:0033089)3.64474675
48mast cell activation (GO:0045576)3.60837510
49alpha-beta T cell differentiation (GO:0046632)3.57704504
50antigen processing and presentation via MHC class Ib (GO:0002475)3.56865535
51NIK/NF-kappaB signaling (GO:0038061)3.56065390
52modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.55688692
53positive regulation by organism of defense response of other organism involved in symbiotic interact3.55688692
54modulation by symbiont of host immune response (GO:0052553)3.55688692
55positive regulation by symbiont of host defense response (GO:0052509)3.55688692
56modulation by symbiont of host defense response (GO:0052031)3.55688692
57modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.55688692
58negative regulation of leukocyte mediated immunity (GO:0002704)3.54740853
59positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.52578772
60signal complex assembly (GO:0007172)3.50134299
61regulation of leukocyte mediated cytotoxicity (GO:0001910)3.49621945
62antigen receptor-mediated signaling pathway (GO:0050851)3.49118104
63T cell homeostasis (GO:0043029)3.48959885
64regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.48117895
65positive regulation of B cell differentiation (GO:0045579)3.46795140
66type I interferon signaling pathway (GO:0060337)3.45171649
67cellular response to type I interferon (GO:0071357)3.45171649
68regulation of memory T cell differentiation (GO:0043380)3.42961871
69response to type I interferon (GO:0034340)3.42135190
70neutrophil activation (GO:0042119)3.36985936
71positive regulation of natural killer cell mediated immunity (GO:0002717)3.36515363
72positive regulation of interleukin-4 production (GO:0032753)3.32994339
73negative regulation of phagocytosis (GO:0050765)3.32843385
74T cell differentiation (GO:0030217)3.27103658
75detection of bacterium (GO:0016045)3.27075909
76alpha-beta T cell activation (GO:0046631)3.26255105
77dendritic cell chemotaxis (GO:0002407)3.23819524
78positive regulation of calcium-mediated signaling (GO:0050850)3.22548760
79positive regulation of isotype switching (GO:0045830)3.20925550
80positive regulation of cell killing (GO:0031343)3.19367934
81detection of other organism (GO:0098543)3.15887080
82regulation of granulocyte differentiation (GO:0030852)3.15437478
83regulation of cell killing (GO:0031341)3.15164144
84negative regulation of type 2 immune response (GO:0002829)3.11617843
85T cell costimulation (GO:0031295)3.08961826
86lymphocyte migration (GO:0072676)3.08831483
87lymphocyte costimulation (GO:0031294)3.07777266
88negative regulation of stress fiber assembly (GO:0051497)3.05738103
89positive regulation of interleukin-2 production (GO:0032743)3.04894915
90dendritic cell migration (GO:0036336)3.02573112
91neutrophil activation involved in immune response (GO:0002283)3.02468632
92granulocyte activation (GO:0036230)3.02240724
93B cell receptor signaling pathway (GO:0050853)3.01792970
94positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.00804900
95T cell activation (GO:0042110)3.00500986
96positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.00349503
97positive regulation of DNA recombination (GO:0045911)3.00125819
98negative regulation of erythrocyte differentiation (GO:0045647)2.99965947
99negative regulation of T cell apoptotic process (GO:0070233)2.98335919
100regulation of alpha-beta T cell activation (GO:0046634)2.97348632

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.37778374
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.60774680
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.16295356
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.14141850
5RUNX_20019798_ChIP-Seq_JUKART_Human4.13727026
6MYB_26560356_Chip-Seq_TH2_Human3.67849092
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.41209741
8MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.32141233
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.25824008
10UTX_26944678_Chip-Seq_JUKART_Human3.17611199
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.12009406
12MYC_22102868_ChIP-Seq_BL_Human3.03651907
13MYB_26560356_Chip-Seq_TH1_Human3.00654040
14MAF_26560356_Chip-Seq_TH1_Human2.91652071
15FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.88740856
16STAT4_19710469_ChIP-ChIP_TH1__Mouse2.79524442
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.74944207
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.55773470
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.46294206
20GATA3_27048872_Chip-Seq_THYMUS_Human2.45231091
21MAF_26560356_Chip-Seq_TH2_Human2.41373859
22SPI1_23547873_ChIP-Seq_NB4_Human2.33175193
23SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.25355807
24E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.23941054
25VDR_21846776_ChIP-Seq_THP-1_Human2.23734466
26BP1_19119308_ChIP-ChIP_Hs578T_Human2.22426343
27IRF8_27001747_Chip-Seq_BMDM_Mouse2.21182815
28SMAD_19615063_ChIP-ChIP_OVARY_Human2.15699778
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.10842414
30RUNX1_22412390_ChIP-Seq_EML_Mouse2.03517679
31VDR_24763502_ChIP-Seq_THP-1_Human1.97145075
32MYB_21317192_ChIP-Seq_ERMYB_Mouse1.93232152
33GATA3_26560356_Chip-Seq_TH2_Human1.90009156
34KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.89724738
35TCF7_22412390_ChIP-Seq_EML_Mouse1.86935542
36SCL_19346495_ChIP-Seq_HPC-7_Human1.85484718
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.82639549
38SPI1_23127762_ChIP-Seq_K562_Human1.82095477
39MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.77973688
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.76919957
41KDM2B_26808549_Chip-Seq_DND41_Human1.76538184
42BRD4_27068464_Chip-Seq_AML-cells_Mouse1.71737541
43BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.69850319
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67634624
45KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.64853519
46STAT6_21828071_ChIP-Seq_BEAS2B_Human1.60044645
47KDM2B_26808549_Chip-Seq_SUP-B15_Human1.56419288
48EGR1_19374776_ChIP-ChIP_THP-1_Human1.53378027
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.48899451
50LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.42799293
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.42639786
52RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.39074007
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.38928669
54RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.33682665
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.33424768
56LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.32857506
57ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.31696370
58NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.31432250
59CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.31384781
60NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.31286053
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26880373
62CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.26089700
63CIITA_25753668_ChIP-Seq_RAJI_Human1.25994119
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23544730
65TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.22395533
66CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22272133
67ELK3_25401928_ChIP-Seq_HUVEC_Human1.19367454
68CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17475662
69PU_27001747_Chip-Seq_BMDM_Mouse1.16315164
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15322511
71VDR_24787735_ChIP-Seq_THP-1_Human1.13663668
72CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13290653
73PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11643322
74PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11014693
75GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10496967
76PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08810914
77GATA1_19941827_ChIP-Seq_MEL_Mouse1.07623792
78VDR_23849224_ChIP-Seq_CD4+_Human0.99392300
79GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98294119
80SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98087694
81GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97931280
82GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96713085
83FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.92883460
84ELF1_20517297_ChIP-Seq_JURKAT_Human0.92246745
85NCOR1_26117541_ChIP-Seq_K562_Human0.91879548
86FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90489757
87GATA1_19941826_ChIP-Seq_K562_Human0.89358472
88BCL6_27268052_Chip-Seq_Bcells_Human0.85779124
89Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.84165277
90RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83072955
91SA1_27219007_Chip-Seq_ERYTHROID_Human0.82793447
92THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.82561080
93FOXP3_21729870_ChIP-Seq_TREG_Human0.82293307
94CTCF_27219007_Chip-Seq_ERYTHROID_Human0.80711564
95SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76297750
96CTCF_21964334_ChIP-Seq_BJAB-B_Human0.75466133
97FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.75461491
98PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75087442
99ETS1_21867929_ChIP-Seq_TH2_Mouse0.74891356
100RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.74567218

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.72933238
2MP0005671_abnormal_response_to4.12741542
3MP0003436_decreased_susceptibility_to3.99639891
4MP0009333_abnormal_splenocyte_physiolog3.68846399
5MP0001800_abnormal_humoral_immune3.45211495
6MP0003724_increased_susceptibility_to3.27895087
7MP0005000_abnormal_immune_tolerance3.27384853
8MP0001835_abnormal_antigen_presentation3.18731321
9MP0005387_immune_system_phenotype3.05902225
10MP0001790_abnormal_immune_system3.05902225
11MP0000685_abnormal_immune_system2.90802693
12MP0002420_abnormal_adaptive_immunity2.86234271
13MP0001819_abnormal_immune_cell2.81691789
14MP0002723_abnormal_immune_serum2.81004440
15MP0005025_abnormal_response_to2.77976964
16MP0009785_altered_susceptibility_to2.73169229
17MP0002452_abnormal_antigen_presenting2.56129855
18MP0000703_abnormal_thymus_morphology2.52780020
19MP0002398_abnormal_bone_marrow2.51799875
20MP0001873_stomach_inflammation2.48746189
21MP0002419_abnormal_innate_immunity2.38422378
22MP0006082_CNS_inflammation2.38178250
23MP0010155_abnormal_intestine_physiology2.32618022
24MP0000716_abnormal_immune_system2.32399072
25MP0003300_gastrointestinal_ulcer2.25770568
26MP0002148_abnormal_hypersensitivity_rea2.25320754
27MP0002405_respiratory_system_inflammati2.24759523
28MP0003866_abnormal_defecation2.13824334
29MP0004947_skin_inflammation2.04596584
30MP0003303_peritoneal_inflammation1.97910531
31MP0002722_abnormal_immune_system1.96416465
32MP0000689_abnormal_spleen_morphology1.91631107
33MP0002429_abnormal_blood_cell1.81462899
34MP0001533_abnormal_skeleton_physiology1.79551253
35MP0005464_abnormal_platelet_physiology1.76747429
36MP0000465_gastrointestinal_hemorrhage1.75995478
37MP0005075_abnormal_melanosome_morpholog1.71005152
38MP0001845_abnormal_inflammatory_respons1.67505767
39MP0001851_eye_inflammation1.64621631
40MP0004381_abnormal_hair_follicle1.62887014
41MP0002396_abnormal_hematopoietic_system1.62313491
42MP0002933_joint_inflammation1.60951909
43MP0002132_abnormal_respiratory_system1.51029211
44MP0002166_altered_tumor_susceptibility1.47940265
45MP0005310_abnormal_salivary_gland1.45093249
46MP0003045_fibrosis1.44313514
47MP0002277_abnormal_respiratory_mucosa1.37492274
48MP0009764_decreased_sensitivity_to1.33070127
49MP0008469_abnormal_protein_level1.27812194
50MP0009278_abnormal_bone_marrow1.25064041
51MP0000490_abnormal_crypts_of1.18940743
52MP0008961_abnormal_basal_metabolism1.14105628
53MP0001853_heart_inflammation1.11811182
54MP0004883_abnormal_blood_vessel1.09080471
55MP0004510_myositis1.05694923
56MP0000858_altered_metastatic_potential1.04492454
57MP0002009_preneoplasia1.02564887
58MP0003172_abnormal_lysosome_physiology1.01954560
59MP0003646_muscle_fatigue0.98026393
60MP0005166_decreased_susceptibility_to0.92129648
61MP0002019_abnormal_tumor_incidence0.91900267
62MP0004130_abnormal_muscle_cell0.90773619
63MP0005645_abnormal_hypothalamus_physiol0.90300437
64MP0002998_abnormal_bone_remodeling0.89845098
65MP0001348_abnormal_lacrimal_gland0.89805779
66MP0002138_abnormal_hepatobiliary_system0.89398579
67MP0002006_tumorigenesis0.88775759
68MP0002163_abnormal_gland_morphology0.86372573
69MP0005451_abnormal_body_composition0.85796058
70MP0009763_increased_sensitivity_to0.85460741
71MP0004808_abnormal_hematopoietic_stem0.85050729
72MP0001919_abnormal_reproductive_system0.83202327
73MP0000015_abnormal_ear_pigmentation0.78359882
74MP0008995_early_reproductive_senescence0.75490105
75MP0003191_abnormal_cellular_cholesterol0.75093390
76MP0003448_altered_tumor_morphology0.74044451
77MP0005390_skeleton_phenotype0.71369450
78MP0001663_abnormal_digestive_system0.70057820
79MP0009765_abnormal_xenobiotic_induced0.69354071
80MP0002693_abnormal_pancreas_physiology0.67512877
81MP0000249_abnormal_blood_vessel0.64390037
82MP0001986_abnormal_taste_sensitivity0.64372984
83MP0005174_abnormal_tail_pigmentation0.60244024
84MP0005083_abnormal_biliary_tract0.57650552
85MP0005397_hematopoietic_system_phenotyp0.55706725
86MP0001545_abnormal_hematopoietic_system0.55706725
87MP0003828_pulmonary_edema0.54188753
88MP0004484_altered_response_of0.53499248
89MP0008260_abnormal_autophagy0.52386027
90MP0002168_other_aberrant_phenotype0.51956308
91MP0000569_abnormal_digit_pigmentation0.50595803
92MP0003795_abnormal_bone_structure0.50221697
93MP0008873_increased_physiological_sensi0.49481489
94MP0005164_abnormal_response_to0.48673299
95MP0008569_lethality_at_weaning0.48451743
96MP0003075_altered_response_to0.45272329
97MP0003806_abnormal_nucleotide_metabolis0.43549096
98MP0009115_abnormal_fat_cell0.43132589
99MP0008874_decreased_physiological_sensi0.38389432
100MP0005381_digestive/alimentary_phenotyp0.35417077

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.29119131
2T lymphocytopenia (HP:0005403)5.79596780
3Abnormality of T cell number (HP:0011839)5.20398431
4Elevated erythrocyte sedimentation rate (HP:0003565)5.18010336
5Stomatitis (HP:0010280)5.07206721
6Severe combined immunodeficiency (HP:0004430)4.77619066
7Increased IgM level (HP:0003496)4.67012682
8Recurrent abscess formation (HP:0002722)4.62925139
9Autoimmune hemolytic anemia (HP:0001890)4.61821761
10IgG deficiency (HP:0004315)4.56862384
11Recurrent bacterial skin infections (HP:0005406)4.48094528
12Increased IgE level (HP:0003212)4.26625890
13Myositis (HP:0100614)4.16336384
14Recurrent fungal infections (HP:0002841)4.10417952
15Abnormality of T cells (HP:0002843)4.03739319
16Encephalitis (HP:0002383)3.99834874
17Abnormality of macrophages (HP:0004311)3.99717161
18Spontaneous hematomas (HP:0007420)3.90120561
19Abnormal delayed hypersensitivity skin test (HP:0002963)3.85368971
20Combined immunodeficiency (HP:0005387)3.80325712
21Panhypogammaglobulinemia (HP:0003139)3.68557604
22Meningitis (HP:0001287)3.67681462
23Granulocytopenia (HP:0001913)3.60906420
24Inflammation of the large intestine (HP:0002037)3.54509072
25Pustule (HP:0200039)3.46921979
26Optic neuritis (HP:0100653)3.46302472
27Retrobulbar optic neuritis (HP:0100654)3.46302472
28Eosinophilia (HP:0001880)3.45810909
29Gastrointestinal inflammation (HP:0004386)3.43376150
30Orchitis (HP:0100796)3.38832160
31Lymphopenia (HP:0001888)3.38105894
32Prolonged bleeding time (HP:0003010)3.36844337
33Obstructive lung disease (HP:0006536)3.36832322
34Chronic obstructive pulmonary disease (HP:0006510)3.36832322
35Gastrointestinal infarctions (HP:0005244)3.35466256
36Mediastinal lymphadenopathy (HP:0100721)3.34392673
37Recurrent viral infections (HP:0004429)3.33893571
38Abnormality of eosinophils (HP:0001879)3.30763798
39B lymphocytopenia (HP:0010976)3.28794668
40Leukocytosis (HP:0001974)3.26117402
41Hypochromic anemia (HP:0001931)3.22309993
42Acute hepatic failure (HP:0006554)3.18320638
43Hematochezia (HP:0002573)3.17574510
44Recurrent gram-negative bacterial infections (HP:0005420)3.14341203
45Abnormality of B cell number (HP:0010975)3.13509452
46IgM deficiency (HP:0002850)3.13054516
47Abnormality of cells of the lymphoid lineage (HP:0012140)3.10350736
48Hypochromic microcytic anemia (HP:0004840)3.09888651
49Hypergammaglobulinemia (HP:0010702)3.07193168
50Vasculitis (HP:0002633)3.00250551
51Recurrent skin infections (HP:0001581)2.91949948
52Epistaxis (HP:0000421)2.72587681
53Recurrent cutaneous fungal infections (HP:0011370)2.71954127
54Chronic mucocutaneous candidiasis (HP:0002728)2.71954127
55Verrucae (HP:0200043)2.71695283
56Papilloma (HP:0012740)2.71695283
57Thyroiditis (HP:0100646)2.70284918
58Gingival bleeding (HP:0000225)2.68554441
59Severe visual impairment (HP:0001141)2.68053710
60Abnormality of T cell physiology (HP:0011840)2.66683647
61Pulmonary infiltrates (HP:0002113)2.63148021
62Microcytic anemia (HP:0001935)2.61689526
63Chest pain (HP:0100749)2.61637096
64Abnormality of the fingertips (HP:0001211)2.56406556
65Recurrent bronchitis (HP:0002837)2.55304964
66Keratoconjunctivitis sicca (HP:0001097)2.54582500
67Autoimmune thrombocytopenia (HP:0001973)2.44906540
68Urticaria (HP:0001025)2.42670016
69Chronic diarrhea (HP:0002028)2.40187880
70Nasal polyposis (HP:0100582)2.39358874
71Slow saccadic eye movements (HP:0000514)2.38308567
72Aplasia/Hypoplasia of the thymus (HP:0010515)2.35296016
73Keratoconjunctivitis (HP:0001096)2.34084333
74Pulmonary embolism (HP:0002204)2.32772338
75Respiratory difficulties (HP:0002880)2.32265347
76Gingivitis (HP:0000230)2.30994983
77Papilledema (HP:0001085)2.27742997
78Lymphoma (HP:0002665)2.24964728
79Increased serum ferritin (HP:0003281)2.23865473
80Colitis (HP:0002583)2.22647038
81Hypoproteinemia (HP:0003075)2.13259198
82Segmental peripheral demyelination/remyelination (HP:0003481)2.11885661
83Sepsis (HP:0100806)2.10676933
84Petechiae (HP:0000967)2.09996647
85Agammaglobulinemia (HP:0004432)2.00416264
86Anorexia (HP:0002039)1.97685202
87Abnormality of iron homeostasis (HP:0011031)1.97606444
88Joint swelling (HP:0001386)1.97023204
89Hemoptysis (HP:0002105)1.95471400
90Increased intramyocellular lipid droplets (HP:0012240)1.93609797
91Cellulitis (HP:0100658)1.88841963
92Hypoplasia of the thymus (HP:0000778)1.88810642
93Alveolar cell carcinoma (HP:0006519)1.88748284
94Increased muscle lipid content (HP:0009058)1.88577869
95Subacute progressive viral hepatitis (HP:0006572)1.87372462
96Recurrent otitis media (HP:0000403)1.87229567
97Abnormality of the nasal mucosa (HP:0000433)1.86475108
98Abnormality of the thymus (HP:0000777)1.84401773
99Episodic fever (HP:0001954)1.79531839
100Stomach cancer (HP:0012126)1.77905478

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.05141285
2TXK4.50904448
3MAP3K104.13923702
4RIPK43.36131769
5PRPF4B3.02106745
6GRK62.89005842
7ZAP702.73141841
8TYK22.69459107
9KDR2.67449713
10ITK2.45221038
11TESK22.13719188
12BTK2.10745231
13FES1.96639839
14CSK1.96609947
15JAK31.75239140
16NLK1.74345084
17TNK21.67684511
18IRAK41.67627586
19CAMKK21.63863681
20SIK31.62779953
21JAK11.61958087
22IKBKE1.60144295
23HCK1.53775493
24LCK1.51955133
25TAOK31.50650240
26TRIB31.48911283
27EPHB11.48382359
28SYK1.46390787
29LRRK21.45024159
30SIK21.40738328
31PASK1.40400449
32CAMKK11.36486367
33BLK1.28204719
34TEC1.27887218
35MAP3K111.17775929
36LYN1.17438395
37FGFR41.15445162
38JAK21.13558655
39MAP2K31.13526665
40PIM11.11344612
41STK100.99522184
42PRKCQ0.97739249
43TBK10.94258380
44MAP3K140.91572160
45ERN10.90103111
46CDK40.88870911
47MAP3K30.85047503
48FGFR30.84851270
49IKBKB0.82996874
50PDK10.80850341
51TAOK10.79143999
52HIPK20.78896246
53CDK120.76190719
54MARK30.75993340
55NEK90.75937239
56MELK0.73978413
57SCYL20.72577885
58MAPK110.72066458
59TAOK20.70908548
60GRK70.66739507
61BMPR20.65482481
62VRK20.64814676
63MAP3K10.64759206
64SMG10.61260402
65ALK0.58662491
66PTK60.58248913
67CDK190.57828712
68FYN0.57253934
69MAP3K50.56174526
70TYRO30.55446771
71MAP3K130.55173923
72MAPK120.54446169
73FGFR20.53475169
74CSF1R0.52684489
75RPS6KA40.49419290
76TLK10.45446756
77KIT0.44213495
78PRKCH0.42746700
79MAPK70.39545359
80PKN20.39504214
81MAP3K120.38770922
82NEK60.36620328
83MARK20.35277015
84EPHA30.34320103
85SIK10.33875784
86RPS6KL10.33338902
87RPS6KC10.33338902
88IRAK10.32265230
89RPS6KA50.31896916
90MAP3K70.31737817
91RET0.30791987
92CLK10.30285480
93RPS6KA60.30171042
94PDPK10.28593860
95CAMK40.28296474
96MAPK30.27431577
97PIK3CG0.27347707
98BRD40.24725399
99NTRK20.24638214
100YES10.23454732

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.22713240
2T cell receptor signaling pathway_Homo sapiens_hsa046603.44794666
3Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.20035968
4Measles_Homo sapiens_hsa051622.60176259
5Autoimmune thyroid disease_Homo sapiens_hsa053202.56013364
6Allograft rejection_Homo sapiens_hsa053302.54795175
7Graft-versus-host disease_Homo sapiens_hsa053322.35225304
8Hematopoietic cell lineage_Homo sapiens_hsa046402.33617575
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.31699138
10Osteoclast differentiation_Homo sapiens_hsa043802.30963339
11Malaria_Homo sapiens_hsa051442.21539265
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.14900693
13B cell receptor signaling pathway_Homo sapiens_hsa046622.05952723
14Leishmaniasis_Homo sapiens_hsa051401.93405657
15Antigen processing and presentation_Homo sapiens_hsa046121.90333189
16Acute myeloid leukemia_Homo sapiens_hsa052211.82295265
17Type I diabetes mellitus_Homo sapiens_hsa049401.80806637
18Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.79136009
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.71553635
20RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.63466643
21Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.61774147
22Chemokine signaling pathway_Homo sapiens_hsa040621.57670006
23Toll-like receptor signaling pathway_Homo sapiens_hsa046201.57078278
24Intestinal immune network for IgA production_Homo sapiens_hsa046721.56203111
25Viral myocarditis_Homo sapiens_hsa054161.54834554
26Herpes simplex infection_Homo sapiens_hsa051681.51743363
27NOD-like receptor signaling pathway_Homo sapiens_hsa046211.43441851
28Staphylococcus aureus infection_Homo sapiens_hsa051501.40598202
29Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.39400464
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.32851288
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.31418198
32Hepatitis B_Homo sapiens_hsa051611.23884756
33Tuberculosis_Homo sapiens_hsa051521.22866594
34Non-small cell lung cancer_Homo sapiens_hsa052231.22273054
35TNF signaling pathway_Homo sapiens_hsa046681.17374734
36Toxoplasmosis_Homo sapiens_hsa051451.17142066
37Shigellosis_Homo sapiens_hsa051311.11796029
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.11105930
39Influenza A_Homo sapiens_hsa051641.10228521
40Platelet activation_Homo sapiens_hsa046111.06155745
41Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.02952308
42Viral carcinogenesis_Homo sapiens_hsa052031.01782706
43Apoptosis_Homo sapiens_hsa042101.00678347
44HTLV-I infection_Homo sapiens_hsa051660.98452148
45Chronic myeloid leukemia_Homo sapiens_hsa052200.98448052
46Colorectal cancer_Homo sapiens_hsa052100.97089270
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.93125345
48Pancreatic cancer_Homo sapiens_hsa052120.92945730
49Epstein-Barr virus infection_Homo sapiens_hsa051690.92345373
50Ribosome_Homo sapiens_hsa030100.92002678
51Prolactin signaling pathway_Homo sapiens_hsa049170.89831900
52African trypanosomiasis_Homo sapiens_hsa051430.87234814
53Legionellosis_Homo sapiens_hsa051340.84155571
54Endocytosis_Homo sapiens_hsa041440.82000127
55VEGF signaling pathway_Homo sapiens_hsa043700.80955908
56Hepatitis C_Homo sapiens_hsa051600.79012476
57Asthma_Homo sapiens_hsa053100.78058924
58Rheumatoid arthritis_Homo sapiens_hsa053230.76446453
59AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.72739550
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72734311
61FoxO signaling pathway_Homo sapiens_hsa040680.68835564
62Pertussis_Homo sapiens_hsa051330.68106357
63ABC transporters_Homo sapiens_hsa020100.66393701
64Neurotrophin signaling pathway_Homo sapiens_hsa047220.65145261
65Renal cell carcinoma_Homo sapiens_hsa052110.63983066
66Proteasome_Homo sapiens_hsa030500.60034431
67Salmonella infection_Homo sapiens_hsa051320.56457965
68Endometrial cancer_Homo sapiens_hsa052130.55174142
69Choline metabolism in cancer_Homo sapiens_hsa052310.54647100
70Sphingolipid signaling pathway_Homo sapiens_hsa040710.53945601
71MAPK signaling pathway_Homo sapiens_hsa040100.52201568
72Regulation of autophagy_Homo sapiens_hsa041400.51786753
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51323700
74Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50361786
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50149672
76mTOR signaling pathway_Homo sapiens_hsa041500.50054875
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47362380
78Ras signaling pathway_Homo sapiens_hsa040140.46675463
79Transcriptional misregulation in cancer_Homo sapiens_hsa052020.45755165
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.44204042
81Phagosome_Homo sapiens_hsa041450.44079801
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.41838869
83HIF-1 signaling pathway_Homo sapiens_hsa040660.41544522
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38883037
85Prostate cancer_Homo sapiens_hsa052150.38280591
86Notch signaling pathway_Homo sapiens_hsa043300.36533346
87ErbB signaling pathway_Homo sapiens_hsa040120.35070763
88Inositol phosphate metabolism_Homo sapiens_hsa005620.33989936
89Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33836438
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.32236136
91Long-term potentiation_Homo sapiens_hsa047200.30705201
92Glioma_Homo sapiens_hsa052140.30543716
93Circadian rhythm_Homo sapiens_hsa047100.30466181
94Dorso-ventral axis formation_Homo sapiens_hsa043200.29652219
95Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28043884
96Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27910606
97Thyroid cancer_Homo sapiens_hsa052160.27515983
98Rap1 signaling pathway_Homo sapiens_hsa040150.24368630
99RNA degradation_Homo sapiens_hsa030180.23959145
100Type II diabetes mellitus_Homo sapiens_hsa049300.19865262

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »