

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 8.09497404 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 7.59823940 |
| 3 | negative thymic T cell selection (GO:0045060) | 7.34902014 |
| 4 | tolerance induction (GO:0002507) | 7.01471078 |
| 5 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.88823426 |
| 6 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.44239474 |
| 7 | positive T cell selection (GO:0043368) | 6.07808106 |
| 8 | regulation of gamma-delta T cell differentiation (GO:0045586) | 6.05583309 |
| 9 | T cell selection (GO:0045058) | 5.93444077 |
| 10 | thymic T cell selection (GO:0045061) | 5.93390519 |
| 11 | response to interleukin-15 (GO:0070672) | 5.80766412 |
| 12 | positive regulation of granulocyte differentiation (GO:0030854) | 5.51070001 |
| 13 | regulation of gamma-delta T cell activation (GO:0046643) | 5.46310101 |
| 14 | Peyers patch development (GO:0048541) | 5.41433810 |
| 15 | mucosal-associated lymphoid tissue development (GO:0048537) | 5.41433810 |
| 16 | leukocyte aggregation (GO:0070486) | 5.34372298 |
| 17 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.34274079 |
| 18 | cellular response to interleukin-15 (GO:0071350) | 5.29914172 |
| 19 | positive thymic T cell selection (GO:0045059) | 5.29233771 |
| 20 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.28160371 |
| 21 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 5.26868402 |
| 22 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.23946258 |
| 23 | negative regulation of cell killing (GO:0031342) | 5.23946258 |
| 24 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.04660521 |
| 25 | negative regulation of myotube differentiation (GO:0010832) | 4.88206149 |
| 26 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.79236635 |
| 27 | regulation of T cell tolerance induction (GO:0002664) | 4.72985792 |
| 28 | T cell migration (GO:0072678) | 4.49143281 |
| 29 | positive regulation of tolerance induction (GO:0002645) | 4.29509201 |
| 30 | regulation of regulatory T cell differentiation (GO:0045589) | 4.18008365 |
| 31 | positive regulation of B cell differentiation (GO:0045579) | 4.16574820 |
| 32 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.10999024 |
| 33 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.10659741 |
| 34 | heart trabecula morphogenesis (GO:0061384) | 4.09829094 |
| 35 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.09445970 |
| 36 | positive regulation of interleukin-2 production (GO:0032743) | 4.05293214 |
| 37 | activated T cell proliferation (GO:0050798) | 4.01425119 |
| 38 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.99971443 |
| 39 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.99971443 |
| 40 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.99643086 |
| 41 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.97437727 |
| 42 | trabecula morphogenesis (GO:0061383) | 3.95124292 |
| 43 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.92986144 |
| 44 | regulation of tolerance induction (GO:0002643) | 3.92779953 |
| 45 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 3.90367738 |
| 46 | T cell receptor signaling pathway (GO:0050852) | 3.88243644 |
| 47 | positive regulation of interleukin-4 production (GO:0032753) | 3.82005861 |
| 48 | alpha-beta T cell differentiation (GO:0046632) | 3.79336748 |
| 49 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.67550747 |
| 50 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.63550464 |
| 51 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.63466233 |
| 52 | negative regulation of T cell mediated immunity (GO:0002710) | 3.61028428 |
| 53 | regulation of interleukin-4 production (GO:0032673) | 3.57923747 |
| 54 | regulation of granulocyte differentiation (GO:0030852) | 3.57614001 |
| 55 | V(D)J recombination (GO:0033151) | 3.55275162 |
| 56 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 3.55150731 |
| 57 | T cell homeostasis (GO:0043029) | 3.55069922 |
| 58 | alpha-beta T cell activation (GO:0046631) | 3.47567470 |
| 59 | natural killer cell differentiation (GO:0001779) | 3.47401132 |
| 60 | signal complex assembly (GO:0007172) | 3.44893290 |
| 61 | regulation of B cell differentiation (GO:0045577) | 3.43877249 |
| 62 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.42065726 |
| 63 | apoptotic process involved in morphogenesis (GO:0060561) | 3.39793058 |
| 64 | T cell differentiation (GO:0030217) | 3.39184467 |
| 65 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.34727361 |
| 66 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.33913633 |
| 67 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.30348332 |
| 68 | regulation of interleukin-2 production (GO:0032663) | 3.29838960 |
| 69 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.27033619 |
| 70 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.26305069 |
| 71 | regulation of alpha-beta T cell activation (GO:0046634) | 3.23266099 |
| 72 | regulation of defense response to virus by virus (GO:0050690) | 3.21710339 |
| 73 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.20605012 |
| 74 | mast cell activation (GO:0045576) | 3.19990116 |
| 75 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.18222564 |
| 76 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.17865638 |
| 77 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.15358805 |
| 78 | B cell receptor signaling pathway (GO:0050853) | 3.11817375 |
| 79 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.11158478 |
| 80 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.09029335 |
| 81 | interferon-gamma production (GO:0032609) | 3.08533776 |
| 82 | cellular response to interleukin-4 (GO:0071353) | 3.07594437 |
| 83 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.07325253 |
| 84 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.03513837 |
| 85 | T cell costimulation (GO:0031295) | 3.01177398 |
| 86 | positive regulation of T cell differentiation (GO:0045582) | 3.00134336 |
| 87 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.99067337 |
| 88 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.97485097 |
| 89 | lymphocyte costimulation (GO:0031294) | 2.97345436 |
| 90 | response to interleukin-4 (GO:0070670) | 2.97014552 |
| 91 | positive regulation of cell killing (GO:0031343) | 2.94448757 |
| 92 | regulation of alpha-beta T cell differentiation (GO:0046637) | 2.94105320 |
| 93 | T-helper cell differentiation (GO:0042093) | 2.87223053 |
| 94 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.87223053 |
| 95 | cardiac ventricle formation (GO:0003211) | 2.83973997 |
| 96 | regulation of cell killing (GO:0031341) | 2.83832772 |
| 97 | T cell activation (GO:0042110) | 2.83737549 |
| 98 | regulation of natural killer cell differentiation (GO:0032823) | 2.82198372 |
| 99 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.80381746 |
| 100 | positive regulation of isotype switching (GO:0045830) | 2.79870312 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.71736047 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.35952750 |
| 3 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.97166639 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.84354871 |
| 5 | MYB_26560356_Chip-Seq_TH2_Human | 3.60495232 |
| 6 | MYC_22102868_ChIP-Seq_BL_Human | 3.56572309 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.29824008 |
| 8 | UTX_26944678_Chip-Seq_JUKART_Human | 3.15013019 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.07749546 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.96981450 |
| 11 | MAF_26560356_Chip-Seq_TH1_Human | 2.96644865 |
| 12 | MYB_26560356_Chip-Seq_TH1_Human | 2.92599625 |
| 13 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.70444209 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.68186222 |
| 15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.66131949 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.59185057 |
| 17 | MAF_26560356_Chip-Seq_TH2_Human | 2.54627106 |
| 18 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.54023148 |
| 19 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.49670780 |
| 20 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.44754912 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.34556463 |
| 22 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.33385407 |
| 23 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.27184549 |
| 24 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.23150115 |
| 25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.21283207 |
| 26 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.17889250 |
| 27 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.15783562 |
| 28 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.15529473 |
| 29 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.12458933 |
| 30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.08672935 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.08557684 |
| 32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.03475581 |
| 33 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.02093596 |
| 34 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.01434500 |
| 35 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.99861492 |
| 36 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.98421293 |
| 37 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.97925065 |
| 38 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.94438240 |
| 39 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.94302634 |
| 40 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.91332116 |
| 41 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.84069226 |
| 42 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.73100542 |
| 43 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.71992093 |
| 44 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.65703034 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62636197 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62443245 |
| 47 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.62236879 |
| 48 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.58604007 |
| 49 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.57934707 |
| 50 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.56168150 |
| 51 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.56051371 |
| 52 | SPI1_23127762_ChIP-Seq_K562_Human | 1.48312096 |
| 53 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46632919 |
| 54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43471358 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.42750027 |
| 56 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.41372673 |
| 57 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.36659780 |
| 58 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.33005578 |
| 59 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.30143706 |
| 60 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.29629492 |
| 61 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.29522067 |
| 62 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.28564343 |
| 63 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.21406706 |
| 64 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.21134520 |
| 65 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.11876164 |
| 66 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.11815621 |
| 67 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.09328415 |
| 68 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.08900895 |
| 69 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.06566507 |
| 70 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.05552448 |
| 71 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.05497456 |
| 72 | GATA1_22025678_ChIP-Seq_K562_Human | 1.04877833 |
| 73 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.04775382 |
| 74 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04269478 |
| 75 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03679424 |
| 76 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02568311 |
| 77 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.01913738 |
| 78 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.01009461 |
| 79 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.97965223 |
| 80 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.97426749 |
| 81 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96989326 |
| 82 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.95340600 |
| 83 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92036671 |
| 84 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91433663 |
| 85 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90959422 |
| 86 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90840215 |
| 87 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90420886 |
| 88 | GATA1_19941826_ChIP-Seq_K562_Human | 0.89801648 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89294780 |
| 90 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88951116 |
| 91 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88930362 |
| 92 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.87865226 |
| 93 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.84246890 |
| 94 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.83630839 |
| 95 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82860090 |
| 96 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.82086991 |
| 97 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.80618142 |
| 98 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.79617265 |
| 99 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.78885788 |
| 100 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.78587492 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.25843292 |
| 2 | MP0005671_abnormal_response_to | 3.85206783 |
| 3 | MP0009333_abnormal_splenocyte_physiolog | 3.52802078 |
| 4 | MP0003436_decreased_susceptibility_to | 3.27145828 |
| 5 | MP0000703_abnormal_thymus_morphology | 3.07685934 |
| 6 | MP0001800_abnormal_humoral_immune | 2.97974131 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.96406433 |
| 8 | MP0001790_abnormal_immune_system | 2.95281290 |
| 9 | MP0005387_immune_system_phenotype | 2.95281290 |
| 10 | MP0001835_abnormal_antigen_presentation | 2.92273005 |
| 11 | MP0000685_abnormal_immune_system | 2.89968301 |
| 12 | MP0003724_increased_susceptibility_to | 2.87406837 |
| 13 | MP0003300_gastrointestinal_ulcer | 2.71189622 |
| 14 | MP0002398_abnormal_bone_marrow | 2.60780071 |
| 15 | MP0002723_abnormal_immune_serum | 2.57662397 |
| 16 | MP0001873_stomach_inflammation | 2.57555434 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.57131199 |
| 18 | MP0001819_abnormal_immune_cell | 2.52883384 |
| 19 | MP0004947_skin_inflammation | 2.48085220 |
| 20 | MP0002405_respiratory_system_inflammati | 2.45046545 |
| 21 | MP0004381_abnormal_hair_follicle | 2.41714642 |
| 22 | MP0002148_abnormal_hypersensitivity_rea | 2.30002158 |
| 23 | MP0005025_abnormal_response_to | 2.25626550 |
| 24 | MP0000716_abnormal_immune_system | 2.23854173 |
| 25 | MP0002396_abnormal_hematopoietic_system | 2.23528566 |
| 26 | MP0003866_abnormal_defecation | 2.23202371 |
| 27 | MP0002722_abnormal_immune_system | 2.22666253 |
| 28 | MP0002452_abnormal_antigen_presenting | 2.17166596 |
| 29 | MP0010155_abnormal_intestine_physiology | 2.09425201 |
| 30 | MP0000689_abnormal_spleen_morphology | 2.05652484 |
| 31 | MP0003279_aneurysm | 2.02866328 |
| 32 | MP0009785_altered_susceptibility_to | 1.98945641 |
| 33 | MP0002009_preneoplasia | 1.93967348 |
| 34 | MP0002419_abnormal_innate_immunity | 1.91316396 |
| 35 | MP0002429_abnormal_blood_cell | 1.83996633 |
| 36 | MP0003303_peritoneal_inflammation | 1.76957867 |
| 37 | MP0003787_abnormal_imprinting | 1.75902485 |
| 38 | MP0002234_abnormal_pharynx_morphology | 1.71172810 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.63256033 |
| 40 | MP0002163_abnormal_gland_morphology | 1.59689639 |
| 41 | MP0000465_gastrointestinal_hemorrhage | 1.58008371 |
| 42 | MP0006082_CNS_inflammation | 1.56212829 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.52937140 |
| 44 | MP0005464_abnormal_platelet_physiology | 1.52163784 |
| 45 | MP0000490_abnormal_crypts_of | 1.49367805 |
| 46 | MP0005310_abnormal_salivary_gland | 1.47986998 |
| 47 | MP0001845_abnormal_inflammatory_respons | 1.44817896 |
| 48 | MP0009278_abnormal_bone_marrow | 1.42834724 |
| 49 | MP0004808_abnormal_hematopoietic_stem | 1.42439263 |
| 50 | MP0001851_eye_inflammation | 1.32752198 |
| 51 | MP0002933_joint_inflammation | 1.14642407 |
| 52 | MP0001533_abnormal_skeleton_physiology | 1.13936044 |
| 53 | MP0001348_abnormal_lacrimal_gland | 1.06805819 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.00493889 |
| 55 | MP0001853_heart_inflammation | 0.96596920 |
| 56 | MP0005451_abnormal_body_composition | 0.95060596 |
| 57 | MP0008469_abnormal_protein_level | 0.94738987 |
| 58 | MP0002006_tumorigenesis | 0.92808998 |
| 59 | MP0004019_abnormal_vitamin_homeostasis | 0.92727667 |
| 60 | MP0002019_abnormal_tumor_incidence | 0.85902575 |
| 61 | MP0001663_abnormal_digestive_system | 0.85280924 |
| 62 | MP0008057_abnormal_DNA_replication | 0.85241855 |
| 63 | MP0004185_abnormal_adipocyte_glucose | 0.85086926 |
| 64 | MP0000858_altered_metastatic_potential | 0.81201768 |
| 65 | MP0009764_decreased_sensitivity_to | 0.79457451 |
| 66 | MP0008260_abnormal_autophagy | 0.79265227 |
| 67 | MP0005379_endocrine/exocrine_gland_phen | 0.74130271 |
| 68 | MP0003077_abnormal_cell_cycle | 0.72615027 |
| 69 | MP0000313_abnormal_cell_death | 0.70531144 |
| 70 | MP0008961_abnormal_basal_metabolism | 0.69273132 |
| 71 | MP0004036_abnormal_muscle_relaxation | 0.69188969 |
| 72 | MP0002877_abnormal_melanocyte_morpholog | 0.66462142 |
| 73 | MP0003183_abnormal_peptide_metabolism | 0.65886602 |
| 74 | MP0002132_abnormal_respiratory_system | 0.65501049 |
| 75 | MP0009763_increased_sensitivity_to | 0.65083870 |
| 76 | MP0003045_fibrosis | 0.61328271 |
| 77 | MP0003959_abnormal_lean_body | 0.61001018 |
| 78 | MP0003693_abnormal_embryo_hatching | 0.60819413 |
| 79 | MP0003828_pulmonary_edema | 0.60469669 |
| 80 | MP0004130_abnormal_muscle_cell | 0.60426212 |
| 81 | MP0001545_abnormal_hematopoietic_system | 0.57715730 |
| 82 | MP0005397_hematopoietic_system_phenotyp | 0.57715730 |
| 83 | MP0001666_abnormal_nutrient_absorption | 0.57521223 |
| 84 | MP0001765_abnormal_ion_homeostasis | 0.57193822 |
| 85 | MP0002693_abnormal_pancreas_physiology | 0.56766332 |
| 86 | MP0005666_abnormal_adipose_tissue | 0.56542367 |
| 87 | MP0003111_abnormal_nucleus_morphology | 0.54784812 |
| 88 | MP0003448_altered_tumor_morphology | 0.53504298 |
| 89 | MP0008877_abnormal_DNA_methylation | 0.51929113 |
| 90 | MP0000733_abnormal_muscle_development | 0.51785300 |
| 91 | MP0003172_abnormal_lysosome_physiology | 0.50684992 |
| 92 | MP0003221_abnormal_cardiomyocyte_apopto | 0.47402946 |
| 93 | MP0002138_abnormal_hepatobiliary_system | 0.47332428 |
| 94 | MP0005535_abnormal_body_temperature | 0.46724152 |
| 95 | MP0004264_abnormal_extraembryonic_tissu | 0.46629225 |
| 96 | MP0000015_abnormal_ear_pigmentation | 0.46219520 |
| 97 | MP0003943_abnormal_hepatobiliary_system | 0.45674615 |
| 98 | MP0001919_abnormal_reproductive_system | 0.45422429 |
| 99 | MP0005330_cardiomyopathy | 0.45265326 |
| 100 | MP0000350_abnormal_cell_proliferation | 0.44624591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the left ventricular outflow tract (HP:0011103) | 6.81889105 |
| 2 | Subaortic stenosis (HP:0001682) | 6.81889105 |
| 3 | Severe combined immunodeficiency (HP:0004430) | 6.12057659 |
| 4 | Eczematoid dermatitis (HP:0000976) | 5.71389340 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 5.31551215 |
| 6 | T lymphocytopenia (HP:0005403) | 5.25472721 |
| 7 | Stomatitis (HP:0010280) | 5.16611338 |
| 8 | Combined immunodeficiency (HP:0005387) | 5.10400590 |
| 9 | Abnormality of T cell number (HP:0011839) | 4.89663702 |
| 10 | Increased IgM level (HP:0003496) | 4.81560970 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.64870086 |
| 12 | Recurrent fungal infections (HP:0002841) | 4.33234704 |
| 13 | Congenital malformation of the right heart (HP:0011723) | 4.29866490 |
| 14 | Double outlet right ventricle (HP:0001719) | 4.29866490 |
| 15 | Increased IgE level (HP:0003212) | 4.10339956 |
| 16 | Abnormality of T cells (HP:0002843) | 4.06422783 |
| 17 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.82701387 |
| 18 | IgG deficiency (HP:0004315) | 3.71101049 |
| 19 | Granulocytopenia (HP:0001913) | 3.68937180 |
| 20 | Panhypogammaglobulinemia (HP:0003139) | 3.66532740 |
| 21 | Recurrent cutaneous fungal infections (HP:0011370) | 3.62834330 |
| 22 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.62834330 |
| 23 | Myositis (HP:0100614) | 3.52622545 |
| 24 | Encephalitis (HP:0002383) | 3.49984187 |
| 25 | Lymphopenia (HP:0001888) | 3.44514339 |
| 26 | Abnormality of eosinophils (HP:0001879) | 3.40899649 |
| 27 | Abnormality of chromosome segregation (HP:0002916) | 3.28933022 |
| 28 | Eosinophilia (HP:0001880) | 3.28661290 |
| 29 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.27990632 |
| 30 | B lymphocytopenia (HP:0010976) | 3.26426320 |
| 31 | Thyroiditis (HP:0100646) | 3.21607331 |
| 32 | Recurrent abscess formation (HP:0002722) | 3.19688676 |
| 33 | Recurrent viral infections (HP:0004429) | 3.19119046 |
| 34 | Leukocytosis (HP:0001974) | 3.17474413 |
| 35 | Meningitis (HP:0001287) | 3.14925655 |
| 36 | Abnormality of B cell number (HP:0010975) | 3.13468435 |
| 37 | Autoimmune thrombocytopenia (HP:0001973) | 3.07724114 |
| 38 | Abnormality of T cell physiology (HP:0011840) | 3.02017299 |
| 39 | Hypergammaglobulinemia (HP:0010702) | 2.99944514 |
| 40 | Truncus arteriosus (HP:0001660) | 2.97866450 |
| 41 | Hypochromic anemia (HP:0001931) | 2.91583247 |
| 42 | Gastrointestinal infarctions (HP:0005244) | 2.91075084 |
| 43 | Orchitis (HP:0100796) | 2.89921625 |
| 44 | Acute hepatic failure (HP:0006554) | 2.86850550 |
| 45 | Recurrent bacterial skin infections (HP:0005406) | 2.84596890 |
| 46 | Pustule (HP:0200039) | 2.84441368 |
| 47 | Spontaneous hematomas (HP:0007420) | 2.84377849 |
| 48 | Abnormality of macrophages (HP:0004311) | 2.84235142 |
| 49 | Joint swelling (HP:0001386) | 2.78228511 |
| 50 | Hypoplasia of the thymus (HP:0000778) | 2.76844169 |
| 51 | Retrobulbar optic neuritis (HP:0100654) | 2.73997530 |
| 52 | Optic neuritis (HP:0100653) | 2.73997530 |
| 53 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.73451977 |
| 54 | Chronic diarrhea (HP:0002028) | 2.72773573 |
| 55 | Hypochromic microcytic anemia (HP:0004840) | 2.71396781 |
| 56 | Chronic obstructive pulmonary disease (HP:0006510) | 2.66272168 |
| 57 | Obstructive lung disease (HP:0006536) | 2.66272168 |
| 58 | Mediastinal lymphadenopathy (HP:0100721) | 2.65832573 |
| 59 | IgM deficiency (HP:0002850) | 2.65815050 |
| 60 | Lymphoma (HP:0002665) | 2.63227345 |
| 61 | Recurrent skin infections (HP:0001581) | 2.62759691 |
| 62 | Prolonged bleeding time (HP:0003010) | 2.62538303 |
| 63 | Recurrent bronchitis (HP:0002837) | 2.60780536 |
| 64 | Vasculitis (HP:0002633) | 2.58904897 |
| 65 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.54877001 |
| 66 | Chest pain (HP:0100749) | 2.46602156 |
| 67 | Hypoplastic left heart (HP:0004383) | 2.45965579 |
| 68 | Abnormality of the fingertips (HP:0001211) | 2.45479965 |
| 69 | Impaired proprioception (HP:0010831) | 2.41165909 |
| 70 | Papilledema (HP:0001085) | 2.38051181 |
| 71 | Cholecystitis (HP:0001082) | 2.30444900 |
| 72 | Abnormal gallbladder physiology (HP:0012438) | 2.30444900 |
| 73 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.25410349 |
| 74 | Keratoconjunctivitis sicca (HP:0001097) | 2.20837269 |
| 75 | Gastrointestinal inflammation (HP:0004386) | 2.17529559 |
| 76 | Slow saccadic eye movements (HP:0000514) | 2.13831999 |
| 77 | Maternal diabetes (HP:0009800) | 2.13819339 |
| 78 | Pulmonary artery stenosis (HP:0004415) | 2.13790564 |
| 79 | Inflammation of the large intestine (HP:0002037) | 2.13655633 |
| 80 | Agammaglobulinemia (HP:0004432) | 2.13541547 |
| 81 | Epistaxis (HP:0000421) | 2.11553581 |
| 82 | Microcytic anemia (HP:0001935) | 2.11465371 |
| 83 | Verrucae (HP:0200043) | 2.09142392 |
| 84 | Papilloma (HP:0012740) | 2.09142392 |
| 85 | Hemoptysis (HP:0002105) | 2.03937312 |
| 86 | Keratoconjunctivitis (HP:0001096) | 2.03153095 |
| 87 | Pulmonary infiltrates (HP:0002113) | 2.02037160 |
| 88 | Episodic fever (HP:0001954) | 2.00845813 |
| 89 | Micronodular cirrhosis (HP:0001413) | 1.97720168 |
| 90 | Dyschromatopsia (HP:0007641) | 1.97440812 |
| 91 | Acute lymphatic leukemia (HP:0006721) | 1.97017072 |
| 92 | Urticaria (HP:0001025) | 1.93490882 |
| 93 | Sepsis (HP:0100806) | 1.93422890 |
| 94 | Hypoplastic heart (HP:0001961) | 1.93288978 |
| 95 | Abnormality of the thymus (HP:0000777) | 1.92795010 |
| 96 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.89635594 |
| 97 | Fatigue (HP:0012378) | 1.81401921 |
| 98 | Cellulitis (HP:0100658) | 1.81149228 |
| 99 | Basal cell carcinoma (HP:0002671) | 1.80087434 |
| 100 | Respiratory difficulties (HP:0002880) | 1.78792584 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.86699942 |
| 2 | MAP4K1 | 4.67534489 |
| 3 | RIPK4 | 3.36377364 |
| 4 | PRPF4B | 2.86660338 |
| 5 | ITK | 2.59703318 |
| 6 | NLK | 2.56109388 |
| 7 | TYK2 | 2.49601185 |
| 8 | ZAP70 | 2.44489451 |
| 9 | FES | 2.21194699 |
| 10 | SIK3 | 2.13094186 |
| 11 | BTK | 2.12987558 |
| 12 | GRK6 | 2.02932126 |
| 13 | FGFR4 | 1.82596794 |
| 14 | MAP3K10 | 1.80736452 |
| 15 | JAK3 | 1.79372206 |
| 16 | SMG1 | 1.73690520 |
| 17 | SYK | 1.70475359 |
| 18 | CSK | 1.65697954 |
| 19 | LCK | 1.64226482 |
| 20 | PASK | 1.62517094 |
| 21 | HCK | 1.61758181 |
| 22 | TNK2 | 1.60046517 |
| 23 | HIPK2 | 1.58591174 |
| 24 | TAOK3 | 1.55638903 |
| 25 | CDK12 | 1.51993340 |
| 26 | MAPK11 | 1.49487099 |
| 27 | SIK2 | 1.48085021 |
| 28 | IRAK4 | 1.47326318 |
| 29 | TRIB3 | 1.42130110 |
| 30 | CAMKK1 | 1.41272328 |
| 31 | PKN2 | 1.35354888 |
| 32 | TEC | 1.32809642 |
| 33 | TESK2 | 1.26195524 |
| 34 | MARK3 | 1.20943523 |
| 35 | CDK6 | 1.20851621 |
| 36 | MAP2K3 | 1.17147165 |
| 37 | FGFR3 | 1.17137552 |
| 38 | LRRK2 | 1.16904812 |
| 39 | LYN | 1.16240927 |
| 40 | JAK1 | 1.15850522 |
| 41 | PTK6 | 1.15372511 |
| 42 | IKBKE | 1.14778498 |
| 43 | TYRO3 | 1.14209972 |
| 44 | JAK2 | 1.13036721 |
| 45 | MAP3K14 | 1.09390015 |
| 46 | ERN1 | 1.08454353 |
| 47 | CLK1 | 1.07606514 |
| 48 | STK10 | 1.03499720 |
| 49 | MAP3K13 | 0.98960250 |
| 50 | SCYL2 | 0.94238227 |
| 51 | CDK4 | 0.93350316 |
| 52 | PRKCQ | 0.93116348 |
| 53 | CDK19 | 0.92250630 |
| 54 | EPHB1 | 0.92074453 |
| 55 | BLK | 0.87936829 |
| 56 | TAOK2 | 0.86462497 |
| 57 | SIK1 | 0.84626650 |
| 58 | BRD4 | 0.83049518 |
| 59 | KDR | 0.80933160 |
| 60 | FGFR2 | 0.78551951 |
| 61 | TAF1 | 0.75430774 |
| 62 | MARK2 | 0.73608752 |
| 63 | CAMKK2 | 0.72333877 |
| 64 | MAP3K1 | 0.68958300 |
| 65 | YES1 | 0.68417552 |
| 66 | MAPK12 | 0.65063495 |
| 67 | TAOK1 | 0.64859285 |
| 68 | TBK1 | 0.60427550 |
| 69 | MAP3K11 | 0.59631906 |
| 70 | UHMK1 | 0.58363075 |
| 71 | PIM1 | 0.56514943 |
| 72 | PDK1 | 0.55556272 |
| 73 | IRAK1 | 0.55159239 |
| 74 | RET | 0.53146753 |
| 75 | STK4 | 0.52526703 |
| 76 | BRAF | 0.52228384 |
| 77 | KSR2 | 0.51816816 |
| 78 | NTRK2 | 0.51462159 |
| 79 | MAPK4 | 0.49541203 |
| 80 | MAP3K7 | 0.48843676 |
| 81 | PRKCH | 0.48235433 |
| 82 | FYN | 0.47649292 |
| 83 | MELK | 0.46323729 |
| 84 | ICK | 0.43913806 |
| 85 | TESK1 | 0.41965967 |
| 86 | CSF1R | 0.41672378 |
| 87 | IKBKB | 0.41135391 |
| 88 | BUB1 | 0.40997303 |
| 89 | PDGFRB | 0.40091624 |
| 90 | CDK9 | 0.39239318 |
| 91 | MAP3K3 | 0.39171796 |
| 92 | MAPK7 | 0.36988101 |
| 93 | BMPR2 | 0.36349530 |
| 94 | MAPKAPK2 | 0.33856079 |
| 95 | MAPK3 | 0.33126697 |
| 96 | VRK2 | 0.30839568 |
| 97 | RPS6KC1 | 0.28165882 |
| 98 | RPS6KL1 | 0.28165882 |
| 99 | RAF1 | 0.27416728 |
| 100 | FGR | 0.26087024 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.40092149 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.00471726 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.20534398 |
| 4 | Measles_Homo sapiens_hsa05162 | 2.90276063 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.80177812 |
| 6 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.55235677 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.20234235 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.19975213 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.16037752 |
| 10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.14206041 |
| 11 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.00383503 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.98470955 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.89656327 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.84309653 |
| 15 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.79017664 |
| 16 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.71116392 |
| 17 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.70814810 |
| 18 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.66337688 |
| 19 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.59959325 |
| 20 | Leishmaniasis_Homo sapiens_hsa05140 | 1.56043804 |
| 21 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.52944024 |
| 22 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.50862662 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.50579511 |
| 24 | Hepatitis B_Homo sapiens_hsa05161 | 1.50403333 |
| 25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.50117838 |
| 26 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.38915751 |
| 27 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.37994740 |
| 28 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.33308323 |
| 29 | Viral myocarditis_Homo sapiens_hsa05416 | 1.32590691 |
| 30 | Thyroid cancer_Homo sapiens_hsa05216 | 1.32454703 |
| 31 | HTLV-I infection_Homo sapiens_hsa05166 | 1.29680994 |
| 32 | Colorectal cancer_Homo sapiens_hsa05210 | 1.24951534 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.18495861 |
| 34 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.14743746 |
| 35 | Malaria_Homo sapiens_hsa05144 | 1.14619666 |
| 36 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.14361074 |
| 37 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.13721073 |
| 38 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.11967751 |
| 39 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.11561578 |
| 40 | Endometrial cancer_Homo sapiens_hsa05213 | 1.10795398 |
| 41 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.05476022 |
| 42 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.02602818 |
| 43 | Influenza A_Homo sapiens_hsa05164 | 1.01627481 |
| 44 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.00711394 |
| 45 | Tuberculosis_Homo sapiens_hsa05152 | 0.96896752 |
| 46 | Ribosome_Homo sapiens_hsa03010 | 0.93566996 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.88809479 |
| 48 | Platelet activation_Homo sapiens_hsa04611 | 0.86393049 |
| 49 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.85527124 |
| 50 | Shigellosis_Homo sapiens_hsa05131 | 0.85227271 |
| 51 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.84761195 |
| 52 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84754969 |
| 53 | Prostate cancer_Homo sapiens_hsa05215 | 0.83407960 |
| 54 | Spliceosome_Homo sapiens_hsa03040 | 0.81529596 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78792365 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.78762909 |
| 57 | Apoptosis_Homo sapiens_hsa04210 | 0.77750488 |
| 58 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.77495099 |
| 59 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.77234790 |
| 60 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.76387972 |
| 61 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.71269555 |
| 62 | Hepatitis C_Homo sapiens_hsa05160 | 0.71042297 |
| 63 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.69480151 |
| 64 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.69181653 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.68583037 |
| 66 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.64854509 |
| 67 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.64333820 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.62095213 |
| 69 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.61000191 |
| 70 | Legionellosis_Homo sapiens_hsa05134 | 0.59514557 |
| 71 | Glioma_Homo sapiens_hsa05214 | 0.58163165 |
| 72 | Endocytosis_Homo sapiens_hsa04144 | 0.57812591 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55178789 |
| 74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.50481607 |
| 75 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49724134 |
| 76 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.49012753 |
| 77 | Cell cycle_Homo sapiens_hsa04110 | 0.48922276 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48395705 |
| 79 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.45514308 |
| 80 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.44049763 |
| 81 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.42929363 |
| 82 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42696381 |
| 83 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.40941386 |
| 84 | Insulin resistance_Homo sapiens_hsa04931 | 0.39834402 |
| 85 | Base excision repair_Homo sapiens_hsa03410 | 0.36231000 |
| 86 | DNA replication_Homo sapiens_hsa03030 | 0.36193034 |
| 87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.35985930 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.35825561 |
| 89 | Long-term potentiation_Homo sapiens_hsa04720 | 0.34460870 |
| 90 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.33771127 |
| 91 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.33595518 |
| 92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.31606408 |
| 93 | Salmonella infection_Homo sapiens_hsa05132 | 0.31491311 |
| 94 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.30836162 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.30159658 |
| 96 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.29956101 |
| 97 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.28984267 |
| 98 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.27916847 |
| 99 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.25810040 |
| 100 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.23991211 |

