TRBV30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)8.69859340
2negative thymic T cell selection (GO:0045060)8.25236569
3positive regulation of gamma-delta T cell activation (GO:0046645)7.78292266
4negative regulation of cell killing (GO:0031342)7.39955343
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.39955343
6positive T cell selection (GO:0043368)7.13762793
7positive regulation of interleukin-2 biosynthetic process (GO:0045086)6.99975143
8positive thymic T cell selection (GO:0045059)6.91280772
9regulation of gamma-delta T cell differentiation (GO:0045586)6.87536493
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.84309413
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.84309413
12thymic T cell selection (GO:0045061)6.82077831
13T cell selection (GO:0045058)6.79285569
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.56135255
15regulation of isotype switching to IgG isotypes (GO:0048302)6.52865875
16regulation of chronic inflammatory response (GO:0002676)6.33605415
17regulation of T cell tolerance induction (GO:0002664)6.31277704
18myeloid dendritic cell differentiation (GO:0043011)6.25025638
19regulation of gamma-delta T cell activation (GO:0046643)6.10709417
20T cell receptor signaling pathway (GO:0050852)5.82924487
21positive regulation of inflammatory response to antigenic stimulus (GO:0002863)5.82255506
22antigen processing and presentation of endogenous antigen (GO:0019883)5.76664502
23regulation of interleukin-6 biosynthetic process (GO:0045408)5.72870177
24T cell costimulation (GO:0031295)5.70956069
25positive regulation of osteoclast differentiation (GO:0045672)5.70530514
26lymphocyte costimulation (GO:0031294)5.63840375
27response to interleukin-15 (GO:0070672)5.41199690
28myeloid dendritic cell activation (GO:0001773)5.40828127
29leukocyte aggregation (GO:0070486)5.28197097
30cellular response to interleukin-15 (GO:0071350)5.16207120
31regulation of immunoglobulin secretion (GO:0051023)5.14952065
32positive regulation of tolerance induction (GO:0002645)5.13187433
33lymph node development (GO:0048535)5.10869168
34regulation of regulatory T cell differentiation (GO:0045589)5.01495625
35regulation of interleukin-2 biosynthetic process (GO:0045076)5.01186739
36positive regulation of T cell cytokine production (GO:0002726)4.94085558
37interferon-gamma production (GO:0032609)4.90082794
38activated T cell proliferation (GO:0050798)4.87418637
39viral transcription (GO:0019083)4.69923955
40antigen receptor-mediated signaling pathway (GO:0050851)4.68039390
41negative regulation of thymocyte apoptotic process (GO:0070244)4.67591659
42positive regulation of interleukin-2 production (GO:0032743)4.58932727
43cytokine biosynthetic process (GO:0042089)4.57991808
44positive regulation of transcription regulatory region DNA binding (GO:2000679)4.56951705
45T cell migration (GO:0072678)4.56455265
46regulation of T cell receptor signaling pathway (GO:0050856)4.56438320
47negative regulation of T cell mediated immunity (GO:0002710)4.52016752
48regulation of alpha-beta T cell proliferation (GO:0046640)4.48599322
49ribosomal small subunit biogenesis (GO:0042274)4.47677102
50regulation of tolerance induction (GO:0002643)4.46943338
51translational termination (GO:0006415)4.41764559
52positive regulation of DNA recombination (GO:0045911)4.39547339
53regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)4.33709998
54cytidine metabolic process (GO:0046087)4.32650624
55cytidine catabolic process (GO:0006216)4.32650624
56cytidine deamination (GO:0009972)4.32650624
57regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.30531986
58negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)4.26480985
59negative regulation of T-helper cell differentiation (GO:0045623)4.26480985
60regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.24247481
61pyrimidine ribonucleoside catabolic process (GO:0046133)4.14671965
62positive regulation of alpha-beta T cell proliferation (GO:0046641)4.11386849
63T-helper 1 type immune response (GO:0042088)4.09839162
64negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)4.06461774
65regulation of T cell cytokine production (GO:0002724)4.04932986
66V(D)J recombination (GO:0033151)4.00884839
67regulation of interleukin-12 biosynthetic process (GO:0045075)4.00520594
68mast cell activation (GO:0045576)3.96035243
69poly(A)+ mRNA export from nucleus (GO:0016973)3.95897650
70regulation of interleukin-8 biosynthetic process (GO:0045414)3.93707356
71NIK/NF-kappaB signaling (GO:0038061)3.91490976
72dendritic cell differentiation (GO:0097028)3.88338169
73positive regulation of humoral immune response (GO:0002922)3.88307745
74regulation of isotype switching (GO:0045191)3.83297809
75DNA deamination (GO:0045006)3.82377532
76tolerance induction (GO:0002507)3.79515736
77cytokine metabolic process (GO:0042107)3.79514507
78regulation of defense response to virus by virus (GO:0050690)3.77881892
79antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.74336474
80positive regulation of myeloid leukocyte differentiation (GO:0002763)3.73434684
81alpha-beta T cell differentiation (GO:0046632)3.72009983
82translational elongation (GO:0006414)3.68326444
83T cell differentiation (GO:0030217)3.67537184
84nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)3.65996266
85nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65518656
86regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.61719859
87alpha-beta T cell activation (GO:0046631)3.61432980
88positive regulation of isotype switching (GO:0045830)3.60457201
89regulation of thymocyte apoptotic process (GO:0070243)3.59771448
90T-helper cell differentiation (GO:0042093)3.58936853
91CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.58936853
92positive regulation of defense response to virus by host (GO:0002230)3.57514211
93negative regulation of T cell apoptotic process (GO:0070233)3.55294539
94SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.54432798
95negative regulation of T cell receptor signaling pathway (GO:0050860)3.54372480
96regulation of B cell receptor signaling pathway (GO:0050855)3.52599221
97cotranslational protein targeting to membrane (GO:0006613)3.49811059
98positive regulation of uterine smooth muscle contraction (GO:0070474)3.49653011
99protein targeting to ER (GO:0045047)3.48432373
100positive regulation of interleukin-4 production (GO:0032753)3.48344396
101cellular protein complex disassembly (GO:0043624)3.47909281
102ribosomal small subunit assembly (GO:0000028)3.47168036
103positive regulation of T cell mediated immunity (GO:0002711)3.45630565
104positive regulation of lymphocyte mediated immunity (GO:0002708)3.44909618
105regulation of immunoglobulin mediated immune response (GO:0002889)3.44165393
106regulation of immunoglobulin production (GO:0002637)3.43883457
107negative regulation of lymphocyte mediated immunity (GO:0002707)3.42653428
108regulation of interleukin-4 production (GO:0032673)3.42095434
109positive regulation of immunoglobulin mediated immune response (GO:0002891)3.37672248
110positive regulation of B cell mediated immunity (GO:0002714)3.37672248
111viral life cycle (GO:0019058)3.34561113
112establishment of protein localization to endoplasmic reticulum (GO:0072599)3.33867610
113T cell homeostasis (GO:0043029)3.32889564
114regulation of interleukin-2 production (GO:0032663)3.32170711
115regulation of B cell mediated immunity (GO:0002712)3.30630938
116regulation of protein heterodimerization activity (GO:0043497)3.29454705
117T cell activation (GO:0042110)3.29315139
118cellular response to interleukin-4 (GO:0071353)3.27565937
119DNA double-strand break processing (GO:0000729)3.27426834
120alpha-beta T cell differentiation involved in immune response (GO:0002293)3.27346491
121alpha-beta T cell activation involved in immune response (GO:0002287)3.27346491
122T cell differentiation involved in immune response (GO:0002292)3.27346491
123regulation of T cell mediated cytotoxicity (GO:0001914)3.27052219
124positive regulation of natural killer cell mediated immunity (GO:0002717)3.25412770
125positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.25412770
126regulation of natural killer cell mediated immunity (GO:0002715)3.24469739
127regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.24469739
128negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.22902990
129immune response-activating cell surface receptor signaling pathway (GO:0002429)3.22271351
130regulation of T cell mediated immunity (GO:0002709)3.21757381
131T cell proliferation (GO:0042098)3.20490324
132protein localization to endoplasmic reticulum (GO:0070972)3.20339070
133positive regulation of granulocyte differentiation (GO:0030854)3.20303588
134maturation of SSU-rRNA (GO:0030490)3.17053608
135positive regulation of T cell activation (GO:0050870)3.16979188
136cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)3.15837061
137positive regulation of adaptive immune response based on somatic recombination of immune receptors b3.12989195
138positive regulation of immunoglobulin production (GO:0002639)3.12310779
139protein complex disassembly (GO:0043241)3.11853400
140mast cell activation involved in immune response (GO:0002279)3.11398798
141mast cell degranulation (GO:0043303)3.11398798
142negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.11264680
143negative regulation of interleukin-12 production (GO:0032695)3.08086437
144regulation of T cell activation (GO:0050863)3.04084632
145translational initiation (GO:0006413)3.01966379
146leukocyte cell-cell adhesion (GO:0007159)3.01542267
147response to interleukin-4 (GO:0070670)3.00130396
148regulation of cytokine production involved in inflammatory response (GO:1900015)11.0221820

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse9.06096240
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human7.13611641
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.45893102
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.16166432
5MYC_22102868_ChIP-Seq_BL_Human3.97795930
6RUNX_20019798_ChIP-Seq_JUKART_Human3.92689828
7FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.80540948
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.79092623
9E2F7_22180533_ChIP-Seq_HELA_Human3.62731063
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.59572082
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.51168243
12STAT4_19710469_ChIP-ChIP_TH1__Mouse3.48843759
13MYB_26560356_Chip-Seq_TH2_Human3.43387589
14FLI1_27457419_Chip-Seq_LIVER_Mouse3.40351495
15UTX_26944678_Chip-Seq_JUKART_Human3.01881394
16MAF_26560356_Chip-Seq_TH1_Human2.87026174
17IRF8_22096565_ChIP-ChIP_GC-B_Human2.81994753
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.78318414
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.76906969
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.75827250
21SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.60909288
22MYB_26560356_Chip-Seq_TH1_Human2.56690481
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.56601357
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.46559326
25PCGF2_27294783_Chip-Seq_ESCs_Mouse2.43044622
26VDR_21846776_ChIP-Seq_THP-1_Human2.40383958
27KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.37707146
28MAF_26560356_Chip-Seq_TH2_Human2.28118637
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.27799890
30GATA3_27048872_Chip-Seq_THYMUS_Human2.21583893
31NOTCH1_21737748_ChIP-Seq_TLL_Human2.09184475
32KDM2B_26808549_Chip-Seq_DND41_Human2.06497970
33SCL_19346495_ChIP-Seq_HPC-7_Human2.00957338
34VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.95870927
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.91559688
36TCF7_22412390_ChIP-Seq_EML_Mouse1.88073654
37KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.85768510
38VDR_24763502_ChIP-Seq_THP-1_Human1.77136988
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.74339368
40E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.61378951
41KDM2B_26808549_Chip-Seq_SUP-B15_Human1.61353973
42GABP_17652178_ChIP-ChIP_JURKAT_Human1.59821603
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59651088
44RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.55916293
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.54475730
46NFE2_27457419_Chip-Seq_LIVER_Mouse1.53372442
47SPI1_23547873_ChIP-Seq_NB4_Human1.53226862
48SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.52235671
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.50084360
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.48464798
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.45128180
52SMAD_19615063_ChIP-ChIP_OVARY_Human1.44411323
53EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.44361273
54MYB_21317192_ChIP-Seq_ERMYB_Mouse1.42936166
55KDM2B_26808549_Chip-Seq_JURKAT_Human1.42587510
56NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.32355061
57HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28860310
58SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27013909
59EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.26970210
60IRF8_27001747_Chip-Seq_BMDM_Mouse1.26872030
61SPI1_23127762_ChIP-Seq_K562_Human1.24398102
62JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.23150751
63ETS1_20019798_ChIP-Seq_JURKAT_Human1.20653383
64IRF8_21731497_ChIP-ChIP_J774_Mouse1.19191116
65STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19029866
66MYC_19079543_ChIP-ChIP_MESCs_Mouse1.18987179
67CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18868966
68RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.17562987
69BRD4_27068464_Chip-Seq_AML-cells_Mouse1.13960894
70EGR1_19032775_ChIP-ChIP_M12_Human1.13463334
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12259193
72GATA1_22025678_ChIP-Seq_K562_Human1.11842927
73GATA3_26560356_Chip-Seq_TH2_Human1.11111228
74EZH2_27294783_Chip-Seq_NPCs_Mouse1.10259239
75ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08642303
76ZNF274_21170338_ChIP-Seq_K562_Hela1.08423603
77PU_27001747_Chip-Seq_BMDM_Mouse1.07684794
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.05356282
79ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04612580
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03498822
81MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00301500
82DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99433999
83STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.97680257
84FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.94778326
85CIITA_25753668_ChIP-Seq_RAJI_Human0.92623089
86E2F4_17652178_ChIP-ChIP_JURKAT_Human0.92555310
87CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91251910
88NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.90576120
89GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90141554
90FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.89803945
91TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88632585
92CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88452413
93MYC_18555785_ChIP-Seq_MESCs_Mouse0.87466563
94SMAD1_18555785_Chip-Seq_ESCs_Mouse0.86685103
95DCP1A_22483619_ChIP-Seq_HELA_Human0.86490336
96PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85039155
97CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.84895676
98FOXM1_23109430_ChIP-Seq_U2OS_Human0.84293325
99VDR_23849224_ChIP-Seq_CD4+_Human0.84177358
100SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.84115837
101GATA3_26560356_Chip-Seq_TH1_Human0.83965408
102AR_21572438_ChIP-Seq_LNCaP_Human0.83531964
103GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82983978
104ELK1_19687146_ChIP-ChIP_HELA_Human0.82838256
105FOXP3_21729870_ChIP-Seq_TREG_Human0.82224720
106PCGF2_27294783_Chip-Seq_NPCs_Mouse0.81589104
107LXR_22292898_ChIP-Seq_THP-1_Human0.81205651
108DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.81123876
109CRX_20693478_ChIP-Seq_RETINA_Mouse0.80759329
110PU.1_20513432_ChIP-Seq_Bcells_Mouse0.79579368
111NMYC_18555785_Chip-Seq_ESCs_Mouse0.79565323
112SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.79303878
113ELK3_25401928_ChIP-Seq_HUVEC_Human0.79089569
114OCT4_18555785_Chip-Seq_ESCs_Mouse0.79026059
115CTCF_18555785_Chip-Seq_ESCs_Mouse0.78934221
116GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.78894595
117CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.78783445
118CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.78318290
119SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77314579
120LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.77047895
121NCOR1_26117541_ChIP-Seq_K562_Human0.74687476
122XRN2_22483619_ChIP-Seq_HELA_Human0.72434556
123RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72179766
124VDR_24787735_ChIP-Seq_THP-1_Human0.70094399
125FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69966366
126CLOCK_20551151_ChIP-Seq_293T_Human0.69715740
127CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.69473015
128GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.68982699
129WDR5_24793694_ChIP-Seq_LNCAP_Human0.64580580
130PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.63192776
131KDM5A_27292631_Chip-Seq_BREAST_Human0.62493389
132CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.60116412
133RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.60007604
134ELF5_23300383_ChIP-Seq_T47D_Human0.59049159
135DROSHA_22980978_ChIP-Seq_HELA_Human0.57420278
136SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.57354892
137TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.56556619

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology6.81627636
2MP0005671_abnormal_response_to4.78745472
3MP0000685_abnormal_immune_system3.63943981
4MP0009333_abnormal_splenocyte_physiolog3.53598054
5MP0000703_abnormal_thymus_morphology3.17922609
6MP0002396_abnormal_hematopoietic_system3.03271465
7MP0001800_abnormal_humoral_immune3.01859893
8MP0005000_abnormal_immune_tolerance2.87760890
9MP0002398_abnormal_bone_marrow2.85219287
10MP0002405_respiratory_system_inflammati2.80575504
11MP0001835_abnormal_antigen_presentation2.72388379
12MP0002420_abnormal_adaptive_immunity2.69706618
13MP0001819_abnormal_immune_cell2.64490836
14MP0002723_abnormal_immune_serum2.61558129
15MP0003300_gastrointestinal_ulcer2.57155818
16MP0002166_altered_tumor_susceptibility2.57063181
17MP0001849_ear_inflammation2.54040022
18MP0004381_abnormal_hair_follicle2.50038999
19MP0005387_immune_system_phenotype2.49512352
20MP0001790_abnormal_immune_system2.49512352
21MP0003303_peritoneal_inflammation2.45189375
22MP0000716_abnormal_immune_system2.43870583
23MP0003436_decreased_susceptibility_to2.36986982
24MP0002722_abnormal_immune_system2.36515498
25MP0002452_abnormal_antigen_presenting2.31520149
26MP0003866_abnormal_defecation2.26223726
27MP0003724_increased_susceptibility_to2.25712258
28MP0005025_abnormal_response_to2.22973860
29MP0005451_abnormal_body_composition2.21968225
30MP0002254_reproductive_system_inflammat2.21514717
31MP0001873_stomach_inflammation2.18807853
32MP0000689_abnormal_spleen_morphology2.18393234
33MP0002006_tumorigenesis2.15124893
34MP0006082_CNS_inflammation2.10842359
35MP0009785_altered_susceptibility_to2.00816764
36MP0010155_abnormal_intestine_physiology1.91546603
37MP0002429_abnormal_blood_cell1.88603588
38MP0004947_skin_inflammation1.83658501
39MP0008057_abnormal_DNA_replication1.80421563
40MP0002933_joint_inflammation1.74091841
41MP0002148_abnormal_hypersensitivity_rea1.71717332
42MP0009764_decreased_sensitivity_to1.62317336
43MP0001853_heart_inflammation1.59068234
44MP0005075_abnormal_melanosome_morpholog1.51080738
45MP0005464_abnormal_platelet_physiology1.48232796
46MP0004510_myositis1.46643396
47MP0001845_abnormal_inflammatory_respons1.45154030
48MP0002419_abnormal_innate_immunity1.42260571
49MP0005408_hypopigmentation1.40333900
50MP0008875_abnormal_xenobiotic_pharmacok1.40071223
51MP0000465_gastrointestinal_hemorrhage1.37878050
52MP0008873_increased_physiological_sensi1.29843200
53MP0004808_abnormal_hematopoietic_stem1.22909677
54MP0002277_abnormal_respiratory_mucosa1.19876500
55MP0002163_abnormal_gland_morphology1.17650065
56MP0002822_catalepsy1.13023747
57MP0005187_abnormal_penis_morphology1.12915781
58MP0000490_abnormal_crypts_of1.11703620
59MP0008007_abnormal_cellular_replicative1.11017405
60MP0001485_abnormal_pinna_reflex1.07299821
61MP0005390_skeleton_phenotype1.06207758
62MP0000604_amyloidosis1.05070342
63MP0003448_altered_tumor_morphology1.04309486
64MP0002095_abnormal_skin_pigmentation1.02892012
65MP0008961_abnormal_basal_metabolism0.96909631
66MP0008469_abnormal_protein_level0.88811058
67MP0001533_abnormal_skeleton_physiology0.88246875
68MP0000858_altered_metastatic_potential0.82629508
69MP0005423_abnormal_somatic_nervous0.81732135
70MP0003329_amyloid_beta_deposits0.80966753
71MP0002019_abnormal_tumor_incidence0.80383967
72MP0005319_abnormal_enzyme/_coenzyme0.78517156
73MP0001765_abnormal_ion_homeostasis0.76884098
74MP0008770_decreased_survivor_rate0.76275868
75MP0005584_abnormal_enzyme/coenzyme_acti0.74895268
76MP0005310_abnormal_salivary_gland0.73772363
77MP0003045_fibrosis0.72185786
78MP0005165_increased_susceptibility_to0.69226823
79MP0001348_abnormal_lacrimal_gland0.68548230
80MP0008058_abnormal_DNA_repair0.68149995
81MP0003943_abnormal_hepatobiliary_system0.67280331
82MP0005379_endocrine/exocrine_gland_phen0.66835158
83MP0001346_abnormal_lacrimal_gland0.64461773
84MP0009763_increased_sensitivity_to0.63231375
85MP0001851_eye_inflammation0.62618780
86MP0003077_abnormal_cell_cycle0.61344911
87MP0001243_abnormal_dermal_layer0.61081787
88MP0005023_abnormal_wound_healing0.60338618
89MP0002136_abnormal_kidney_physiology0.59373819
90MP0000920_abnormal_myelination0.59121838
91MP0000015_abnormal_ear_pigmentation0.57654729
92MP0002138_abnormal_hepatobiliary_system0.56730890
93MP0000609_abnormal_liver_physiology0.56427905
94MP0001663_abnormal_digestive_system0.55569269
95MP0005397_hematopoietic_system_phenotyp0.55186251
96MP0001545_abnormal_hematopoietic_system0.55186251
97MP0009765_abnormal_xenobiotic_induced0.55040677
98MP0001764_abnormal_homeostasis0.54946800
99MP0003787_abnormal_imprinting0.53745980
100MP0009931_abnormal_skin_appearance0.53503433
101MP0003172_abnormal_lysosome_physiology0.52694678
102MP0010352_gastrointestinal_tract_polyps0.52115665
103MP0004957_abnormal_blastocyst_morpholog0.49924445
104MP0000477_abnormal_intestine_morphology0.48717460
105MP0002998_abnormal_bone_remodeling0.47609191
106MP0002132_abnormal_respiratory_system0.47490146
107MP0000598_abnormal_liver_morphology0.47133284
108MP0001216_abnormal_epidermal_layer0.44180936
109MP0000627_abnormal_mammary_gland0.44009906
110MP0002332_abnormal_exercise_endurance0.43498371
111MP0000639_abnormal_adrenal_gland0.42296153
112MP0001191_abnormal_skin_condition0.41771025
113MP0003828_pulmonary_edema0.40195131
114MP0003252_abnormal_bile_duct0.40006022
115MP0008569_lethality_at_weaning0.39723908
116MP0003795_abnormal_bone_structure0.38333195
117MP0005381_digestive/alimentary_phenotyp0.37381434
118MP0008874_decreased_physiological_sensi0.36984872
119MP0000249_abnormal_blood_vessel0.36760744
120MP0002876_abnormal_thyroid_physiology0.36340122
121MP0002083_premature_death0.36151566
122MP0005174_abnormal_tail_pigmentation0.35684572
123MP0002693_abnormal_pancreas_physiology0.35123016
124MP0004134_abnormal_chest_morphology0.34935924
125MP0008872_abnormal_physiological_respon0.34222396
126MP0005636_abnormal_mineral_homeostasis0.34013176
127MP0010094_abnormal_chromosome_stability0.33200488
128MP0000367_abnormal_coat/_hair0.29601102
129MP0001501_abnormal_sleep_pattern0.29008698
130MP0000350_abnormal_cell_proliferation0.28066869

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)8.41231434
2Abnormality of T cell number (HP:0011839)8.05866735
3Severe combined immunodeficiency (HP:0004430)5.67877463
4Stomatitis (HP:0010280)5.63005554
5Combined immunodeficiency (HP:0005387)5.45658396
6Elevated erythrocyte sedimentation rate (HP:0003565)5.36549165
7Chronic otitis media (HP:0000389)5.13338047
8Abnormality of T cells (HP:0002843)4.99953307
9Eosinophilia (HP:0001880)4.54798399
10Increased IgM level (HP:0003496)4.50469459
11Recurrent viral infections (HP:0004429)4.45844574
12Periodontitis (HP:0000704)4.37622537
13IgG deficiency (HP:0004315)4.24125934
14Lipid accumulation in hepatocytes (HP:0006561)4.22398005
15Keratoconjunctivitis (HP:0001096)4.20256302
16Recurrent bronchitis (HP:0002837)4.15004620
17Abnormality of eosinophils (HP:0001879)4.11340966
18Panhypogammaglobulinemia (HP:0003139)4.08567309
19Recurrent fungal infections (HP:0002841)4.04776602
20Nasal polyposis (HP:0100582)3.93519042
21Cheilitis (HP:0100825)3.92561035
22B lymphocytopenia (HP:0010976)3.90456421
23Abnormality of B cell number (HP:0010975)3.90456421
24Premature loss of primary teeth (HP:0006323)3.63520183
25Granulocytopenia (HP:0001913)3.61888157
26Leukocytosis (HP:0001974)3.60389267
27Joint swelling (HP:0001386)3.51640809
28Abnormality of the prostate (HP:0008775)3.50968900
29Recurrent skin infections (HP:0001581)3.50016459
30Renal Fanconi syndrome (HP:0001994)3.49554652
31Orchitis (HP:0100796)3.44641498
32Eczematoid dermatitis (HP:0000976)3.44288442
33Autoimmune hemolytic anemia (HP:0001890)3.43148384
34Thyroiditis (HP:0100646)3.30933575
35Abnormality of the nasal mucosa (HP:0000433)3.20877221
36Prostate neoplasm (HP:0100787)3.19766049
37IgM deficiency (HP:0002850)3.14798877
38Increased intramyocellular lipid droplets (HP:0012240)3.11383887
39Abnormal hair whorl (HP:0010721)3.08266595
40Pustule (HP:0200039)3.07276851
41Exertional dyspnea (HP:0002875)3.06401702
42Hypoplasia of the thymus (HP:0000778)3.04219154
43Abnormality of the fingertips (HP:0001211)2.93325977
44Lymphopenia (HP:0001888)2.90194778
45Myositis (HP:0100614)2.86514113
46Increased muscle lipid content (HP:0009058)2.86103439
47Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.85802906
48Abnormality of cells of the lymphoid lineage (HP:0012140)2.84118510
4911 pairs of ribs (HP:0000878)2.83460822
50Loss of speech (HP:0002371)2.79268074
51Malignant hyperthermia (HP:0002047)2.73686531
52Abnormality of cells of the erythroid lineage (HP:0012130)2.71217279
53Porencephaly (HP:0002132)2.63209257
54Gastrointestinal infarctions (HP:0005244)2.62374074
55Median cleft lip (HP:0000161)2.62185618
56Limb hypertonia (HP:0002509)2.60160188
57Hypergammaglobulinemia (HP:0010702)2.59612025
58Papilloma (HP:0012740)2.59111252
59Verrucae (HP:0200043)2.59111252
60Chronic mucocutaneous candidiasis (HP:0002728)2.59096349
61Recurrent cutaneous fungal infections (HP:0011370)2.59096349
62Chronic obstructive pulmonary disease (HP:0006510)2.58725989
63Obstructive lung disease (HP:0006536)2.58725989
64Lower limb hyperreflexia (HP:0002395)2.55885742
65Chest pain (HP:0100749)2.54688817
66Hemoptysis (HP:0002105)2.53092244
67Long clavicles (HP:0000890)2.50276270
68Abnormal delayed hypersensitivity skin test (HP:0002963)2.49829533
69Basal cell carcinoma (HP:0002671)2.48484431
70Chronic diarrhea (HP:0002028)2.47856473
71Skin rash (HP:0000988)2.46145396
72Thrombocytosis (HP:0001894)2.46006815
73Pulmonary infiltrates (HP:0002113)2.45331297
74Chronic sinusitis (HP:0011109)2.45197959
75Toxemia of pregnancy (HP:0100603)2.44872857
76Metaphyseal cupping (HP:0003021)2.43069868
77Abnormal number of erythroid precursors (HP:0012131)2.41545070
78Abnormal pupillary function (HP:0007686)2.41083773
79Autoimmune thrombocytopenia (HP:0001973)2.40912974
80Acute hepatic failure (HP:0006554)2.39279336
81Increased circulating renin level (HP:0000848)2.38737722
82Respiratory difficulties (HP:0002880)2.38525433
83Meningitis (HP:0001287)2.36119972
84IgA deficiency (HP:0002720)2.35441052
85Pancreatic islet-cell hyperplasia (HP:0004510)2.32436851
86Abnormality of T cell physiology (HP:0011840)2.31266777
87Bronchitis (HP:0012387)2.30966456
88Spontaneous hematomas (HP:0007420)2.30741195
89Keratitis (HP:0000491)2.30321863
90Seborrheic dermatitis (HP:0001051)2.29960992
91Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.29758557
92Lymphoma (HP:0002665)2.27238909
93Abnormal foot bone ossification (HP:0010675)2.25856205
94Generalized aminoaciduria (HP:0002909)2.24136595
95Macrocytic anemia (HP:0001972)2.23910698
96Pulmonary embolism (HP:0002204)2.22797240
97Ureteral stenosis (HP:0000071)2.21948045
98Vasculitis (HP:0002633)2.21511664
99Volvulus (HP:0002580)2.20574591
100Amyotrophic lateral sclerosis (HP:0007354)2.19564930
101Recurrent sinusitis (HP:0011108)2.18431883
102Increased IgE level (HP:0003212)2.16760181
103Abnormal platelet volume (HP:0011876)2.16408267
104Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.15894378
105Short 4th metacarpal (HP:0010044)2.15894378
106Abnormality of the pleura (HP:0002103)2.15695572
107Neutropenia (HP:0001875)2.12368729
108Gangrene (HP:0100758)2.08837319
109Reticulocytopenia (HP:0001896)2.08684767
110Abnormality of renal resorption (HP:0011038)2.07744771
111Mediastinal lymphadenopathy (HP:0100721)2.06496214
112Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.04157718
113Fatigue (HP:0012378)2.03709692
114Recurrent otitis media (HP:0000403)2.03434052
115Increased neuronal autofluorescent lipopigment (HP:0002074)2.03307708
116Progressive inability to walk (HP:0002505)2.02297928
117Decreased activity of mitochondrial respiratory chain (HP:0008972)2.01695361
118Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.01695361
119Papilledema (HP:0001085)1.99532791
120Subacute progressive viral hepatitis (HP:0006572)1.98860276
121Encephalitis (HP:0002383)1.97200162
122Abnormality of the endocardium (HP:0004306)1.97003181
123Aplasia/Hypoplasia of the thymus (HP:0010515)1.96026856
124Abnormality of macrophages (HP:0004311)1.94355299
125Ureteral obstruction (HP:0006000)1.93514126
126Epistaxis (HP:0000421)1.92977968
127Retrobulbar optic neuritis (HP:0100654)1.92769244
128Optic neuritis (HP:0100653)1.92769244
129Hyperkalemia (HP:0002153)1.90714510
130Xerostomia (HP:0000217)1.90225705
131Cutis marmorata (HP:0000965)1.89786583
132Episodic fever (HP:0001954)1.89697260
133Hepatosplenomegaly (HP:0001433)1.89473077
134Pallor (HP:0000980)1.88469839
135Polyneuropathy (HP:0001271)1.88459507
136Acute lymphatic leukemia (HP:0006721)1.87066551
137Hypoproteinemia (HP:0003075)1.86419823
138Keratoconjunctivitis sicca (HP:0001097)1.86280795
139Increased density of long bones (HP:0006392)1.84663570
140Arterial thrombosis (HP:0004420)1.84525417
141Skin ulcer (HP:0200042)1.82399080
142Amaurosis fugax (HP:0100576)1.79575437
143Hepatitis (HP:0012115)1.77980607
144Bicuspid aortic valve (HP:0001647)1.75673046
145Increased mean platelet volume (HP:0011877)1.74655438
146Gingival bleeding (HP:0000225)1.72817352
147Emphysema (HP:0002097)1.71127192
148Increased hepatocellular lipid droplets (HP:0006565)1.70181248

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.36702689
2MAP4K15.64216729
3NEK13.90637928
4ACVR1B3.72705823
5ZAP703.27804992
6ITK3.07998401
7FGFR42.77845520
8STK102.62591140
9GRK62.42104202
10JAK32.26009624
11SIK22.25901715
12EEF2K2.08903928
13NLK2.01998633
14TYK21.95612086
15LCK1.92628777
16MAP3K101.86549332
17LRRK21.79793863
18PKN21.78360461
19FGFR31.74597275
20IKBKE1.71682591
21CSK1.68362614
22TEC1.67919886
23SYK1.61969777
24JAK11.60788577
25MST41.59403800
26NME21.55504268
27ERN11.53350304
28MAP2K31.45413629
29MAP3K141.43628643
30TESK21.43578459
31NTRK21.40055834
32PRKCQ1.37648178
33TLK11.34163555
34FES1.32719921
35RIPK41.27459726
36PRKCH1.26995082
37HCK1.26753648
38PNCK1.26620360
39ALK1.25034901
40TAOK31.19881602
41MAP3K31.18052687
42WNK41.16602142
43MAP2K61.16527042
44CAMKK21.13710268
45MAP3K121.08498602
46DYRK31.05736192
47CDK191.00780105
48CLK10.94832579
49CAMKK10.94457061
50JAK20.93541288
51TRIB30.92897502
52MAP3K110.92146931
53TAOK10.90763341
54BTK0.90112879
55EIF2AK30.88593860
56STK390.88314770
57TBK10.87488631
58DYRK1B0.86485987
59BCKDK0.85784162
60RPS6KL10.84921907
61RPS6KC10.84921907
62MAP3K130.83132474
63RPS6KA60.82742041
64MARK30.81736509
65OXSR10.80577640
66PTK60.78670853
67WNK10.78116368
68TYRO30.77239848
69NEK60.76631531
70IKBKB0.73651629
71MAPK110.71284763
72EIF2AK10.71161438
73MAP3K70.70957424
74TGFBR10.69784743
75RPS6KB20.68760924
76SIK10.68242056
77EPHB10.68049883
78IRAK40.66590775
79SGK20.66468388
80KIT0.65794415
81PDGFRB0.64809273
82MAPK40.64295410
83FGFR20.63449679
84RPS6KB10.63298739
85TSSK60.63216923
86BLK0.61638905
87KDR0.60683345
88LYN0.60104708
89INSR0.60010285
90SMG10.59920353
91FYN0.58709742
92UHMK10.57724890
93CHUK0.56300517
94RPS6KA40.55627588
95MAPKAPK30.55556110
96PIM10.55057505
97VRK10.53726439
98SIK30.52971844
99HIPK20.52903958
100ILK0.52750682
101MARK20.52615105
102TTN0.52411148
103TRIM280.51816287
104ADRBK20.51765203
105PASK0.51120750
106EIF2AK20.46227382
107PDK10.43778726
108NME10.43325477
109ROCK20.42526348
110CDK70.41183033
111MAPK120.40420503
112CDK120.38364399
113EPHA30.38215574
114TNK20.38101312
115CDK40.35272199
116CSF1R0.33177454
117CAMK1G0.32768464
118CAMK40.32132381
119MAPK30.32035769
120PRKG20.32027154
121DAPK10.31947716
122ATR0.31166584
123BRD40.30902836
124FGFR10.30472708
125IRAK10.30322495
126SGK2230.29666090
127SGK4940.29666090
128EGFR0.29289940
129MARK10.28275194
130DYRK1A0.27318052
131MAPK90.27122640
132PRKCB0.26980511
133SGK10.26404243
134DYRK20.26224822
135MAP3K10.25606445
136BCR0.25593544
137PRPF4B0.24150352
138IGF1R0.23756130
139SGK30.23474450
140PHKG10.22795097
141PHKG20.22795097
142MAPK70.22267774
143CDK90.21974818
144MAPK80.21761158
145TAOK20.21101291
146CSNK2A20.21070813
147RET0.20969127
148MUSK0.20946819

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.17938668
2Caffeine metabolism_Homo sapiens_hsa002325.87317529
3T cell receptor signaling pathway_Homo sapiens_hsa046604.83147944
4Ribosome_Homo sapiens_hsa030103.09047489
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.91907754
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.88103693
7Allograft rejection_Homo sapiens_hsa053302.74640016
8Measles_Homo sapiens_hsa051622.59417868
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.53841959
10Autoimmune thyroid disease_Homo sapiens_hsa053202.48154534
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.35940834
12Non-homologous end-joining_Homo sapiens_hsa034502.35250192
13Hematopoietic cell lineage_Homo sapiens_hsa046402.06508113
14Viral myocarditis_Homo sapiens_hsa054162.06220119
15Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.92104768
16Graft-versus-host disease_Homo sapiens_hsa053321.81409721
17Antigen processing and presentation_Homo sapiens_hsa046121.68673201
18Osteoclast differentiation_Homo sapiens_hsa043801.68203862
19SNARE interactions in vesicular transport_Homo sapiens_hsa041301.67042967
20Leishmaniasis_Homo sapiens_hsa051401.56952334
21Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.39378766
22Leukocyte transendothelial migration_Homo sapiens_hsa046701.38672716
23Spliceosome_Homo sapiens_hsa030401.36954997
24Herpes simplex infection_Homo sapiens_hsa051681.31300958
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.30503218
26Acute myeloid leukemia_Homo sapiens_hsa052211.30230971
27B cell receptor signaling pathway_Homo sapiens_hsa046621.30159673
28Type I diabetes mellitus_Homo sapiens_hsa049401.28535775
29Chemokine signaling pathway_Homo sapiens_hsa040621.27812259
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.26126811
31Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23415861
32Pancreatic cancer_Homo sapiens_hsa052121.21939973
33Toxoplasmosis_Homo sapiens_hsa051451.15406508
34Colorectal cancer_Homo sapiens_hsa052101.12593563
35Asthma_Homo sapiens_hsa053101.09262489
36Hepatitis B_Homo sapiens_hsa051611.08568973
37HTLV-I infection_Homo sapiens_hsa051661.06105850
38Staphylococcus aureus infection_Homo sapiens_hsa051501.04445997
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.01825393
40RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.00587339
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.92109085
42Chronic myeloid leukemia_Homo sapiens_hsa052200.90402164
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87861550
44Shigellosis_Homo sapiens_hsa051310.86396616
45NOD-like receptor signaling pathway_Homo sapiens_hsa046210.85275387
46AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79915413
47Notch signaling pathway_Homo sapiens_hsa043300.78887584
48Platelet activation_Homo sapiens_hsa046110.78470379
49Homologous recombination_Homo sapiens_hsa034400.77966546
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.77941724
51Apoptosis_Homo sapiens_hsa042100.74291929
52Epstein-Barr virus infection_Homo sapiens_hsa051690.74026719
53mRNA surveillance pathway_Homo sapiens_hsa030150.70455914
54Prolactin signaling pathway_Homo sapiens_hsa049170.69247332
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69178636
56Viral carcinogenesis_Homo sapiens_hsa052030.63978873
57Regulation of autophagy_Homo sapiens_hsa041400.63827150
58Hepatitis C_Homo sapiens_hsa051600.62500771
59TNF signaling pathway_Homo sapiens_hsa046680.61579726
60Influenza A_Homo sapiens_hsa051640.60652928
61VEGF signaling pathway_Homo sapiens_hsa043700.58617140
62RNA degradation_Homo sapiens_hsa030180.57805891
63Non-small cell lung cancer_Homo sapiens_hsa052230.56860308
64Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56149319
65Malaria_Homo sapiens_hsa051440.55178431
66Sulfur relay system_Homo sapiens_hsa041220.54013767
67Renal cell carcinoma_Homo sapiens_hsa052110.53890627
68Tuberculosis_Homo sapiens_hsa051520.53192771
69Dorso-ventral axis formation_Homo sapiens_hsa043200.53001558
70MAPK signaling pathway_Homo sapiens_hsa040100.52457857
71Toll-like receptor signaling pathway_Homo sapiens_hsa046200.52215667
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.51842131
73One carbon pool by folate_Homo sapiens_hsa006700.50585785
74Inositol phosphate metabolism_Homo sapiens_hsa005620.49721026
75Rheumatoid arthritis_Homo sapiens_hsa053230.48391882
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47711416
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.47305214
78Protein export_Homo sapiens_hsa030600.46061191
79Insulin resistance_Homo sapiens_hsa049310.44874270
80Endocytosis_Homo sapiens_hsa041440.43437183
81Endometrial cancer_Homo sapiens_hsa052130.42724712
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41891321
83Pertussis_Homo sapiens_hsa051330.41528569
84Prostate cancer_Homo sapiens_hsa052150.41508970
85Salmonella infection_Homo sapiens_hsa051320.40708359
86Small cell lung cancer_Homo sapiens_hsa052220.38470146
87MicroRNAs in cancer_Homo sapiens_hsa052060.37722224
88Rap1 signaling pathway_Homo sapiens_hsa040150.37541723
89mTOR signaling pathway_Homo sapiens_hsa041500.37383269
90Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.36125477
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.34767540
92Long-term potentiation_Homo sapiens_hsa047200.34573106
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33374419
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.32781962
95Thyroid cancer_Homo sapiens_hsa052160.32334188
96African trypanosomiasis_Homo sapiens_hsa051430.32097445
97Legionellosis_Homo sapiens_hsa051340.31180133
98FoxO signaling pathway_Homo sapiens_hsa040680.30427997
99Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.30357473
100Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28610779
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28117430
102Fanconi anemia pathway_Homo sapiens_hsa034600.27439475
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27050230
104Glycosaminoglycan degradation_Homo sapiens_hsa005310.26936129
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.26927585
106RNA polymerase_Homo sapiens_hsa030200.26883957
107Ether lipid metabolism_Homo sapiens_hsa005650.26876635
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26629496
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23550108
110Mismatch repair_Homo sapiens_hsa034300.22116936
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.21918030
112Proteasome_Homo sapiens_hsa030500.21550324
113RNA transport_Homo sapiens_hsa030130.20957555
114Adherens junction_Homo sapiens_hsa045200.20677504
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.20021651
116Cocaine addiction_Homo sapiens_hsa050300.19429162
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.18528265
118p53 signaling pathway_Homo sapiens_hsa041150.18358585
119Adipocytokine signaling pathway_Homo sapiens_hsa049200.18089284
120Nucleotide excision repair_Homo sapiens_hsa034200.17214836
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.15319175
122Propanoate metabolism_Homo sapiens_hsa006400.14972343
123Phototransduction_Homo sapiens_hsa047440.13910989
124Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.13014692
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12637960
126Linoleic acid metabolism_Homo sapiens_hsa005910.08966930

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