

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 8.99527715 |
| 2 | negative thymic T cell selection (GO:0045060) | 8.62207977 |
| 3 | positive regulation of granulocyte differentiation (GO:0030854) | 7.49710235 |
| 4 | V(D)J recombination (GO:0033151) | 7.10865018 |
| 5 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.77157378 |
| 6 | thymic T cell selection (GO:0045061) | 6.67313002 |
| 7 | positive T cell selection (GO:0043368) | 6.45894530 |
| 8 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.30684238 |
| 9 | T cell selection (GO:0045058) | 6.21332723 |
| 10 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.12895895 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 6.10392190 |
| 12 | positive thymic T cell selection (GO:0045059) | 5.98826573 |
| 13 | T cell migration (GO:0072678) | 5.94420494 |
| 14 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.16172170 |
| 15 | cellular response to interleukin-4 (GO:0071353) | 4.96184219 |
| 16 | negative regulation of B cell mediated immunity (GO:0002713) | 4.71699466 |
| 17 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 4.71699466 |
| 18 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.67484930 |
| 19 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.55426568 |
| 20 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.51609849 |
| 21 | positive regulation of B cell differentiation (GO:0045579) | 4.51474710 |
| 22 | response to interleukin-4 (GO:0070670) | 4.48127362 |
| 23 | Peyers patch development (GO:0048541) | 4.46858539 |
| 24 | mucosal-associated lymphoid tissue development (GO:0048537) | 4.46858539 |
| 25 | regulation of granulocyte differentiation (GO:0030852) | 4.45301658 |
| 26 | regulation of gamma-delta T cell activation (GO:0046643) | 4.41684395 |
| 27 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.39305713 |
| 28 | regulation of interleukin-4 production (GO:0032673) | 4.38068647 |
| 29 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.36459110 |
| 30 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.34131062 |
| 31 | mast cell activation (GO:0045576) | 4.30073167 |
| 32 | B cell proliferation (GO:0042100) | 4.20532140 |
| 33 | alpha-beta T cell differentiation (GO:0046632) | 4.20056111 |
| 34 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.19664805 |
| 35 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.18191021 |
| 36 | leukocyte aggregation (GO:0070486) | 4.17506151 |
| 37 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.13643551 |
| 38 | negative regulation of cell killing (GO:0031342) | 3.98315693 |
| 39 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.98315693 |
| 40 | response to interleukin-15 (GO:0070672) | 3.98229599 |
| 41 | mast cell degranulation (GO:0043303) | 3.92422976 |
| 42 | mast cell activation involved in immune response (GO:0002279) | 3.92422976 |
| 43 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.91586119 |
| 44 | T cell receptor signaling pathway (GO:0050852) | 3.89045430 |
| 45 | regulation of T cell tolerance induction (GO:0002664) | 3.86209393 |
| 46 | hypothalamus development (GO:0021854) | 3.83138341 |
| 47 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.82724161 |
| 48 | alpha-beta T cell activation (GO:0046631) | 3.76979055 |
| 49 | diterpenoid biosynthetic process (GO:0016102) | 3.72972679 |
| 50 | positive regulation of tolerance induction (GO:0002645) | 3.68958865 |
| 51 | positive regulation of interleukin-4 production (GO:0032753) | 3.66233295 |
| 52 | regulation of B cell differentiation (GO:0045577) | 3.65690021 |
| 53 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.63779632 |
| 54 | membrane raft organization (GO:0031579) | 3.63525190 |
| 55 | T cell differentiation (GO:0030217) | 3.61720801 |
| 56 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.60163897 |
| 57 | cellular response to interleukin-15 (GO:0071350) | 3.55978885 |
| 58 | generation of neurons (GO:0048699) | 3.52515546 |
| 59 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.51589662 |
| 60 | positive regulation of interleukin-2 production (GO:0032743) | 3.47475311 |
| 61 | negative regulation of T cell mediated immunity (GO:0002710) | 3.43591904 |
| 62 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.42514059 |
| 63 | hepatocyte apoptotic process (GO:0097284) | 3.39768626 |
| 64 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.39213614 |
| 65 | tolerance induction (GO:0002507) | 3.38349433 |
| 66 | localization within membrane (GO:0051668) | 3.38219162 |
| 67 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.38204026 |
| 68 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.36452646 |
| 69 | positive regulation of macrophage differentiation (GO:0045651) | 3.35384344 |
| 70 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.35238111 |
| 71 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.35238111 |
| 72 | lymphocyte costimulation (GO:0031294) | 3.32016875 |
| 73 | T cell costimulation (GO:0031295) | 3.30822173 |
| 74 | lymphocyte migration (GO:0072676) | 3.24733039 |
| 75 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.24696563 |
| 76 | activated T cell proliferation (GO:0050798) | 3.22173973 |
| 77 | protein targeting to Golgi (GO:0000042) | 3.18979924 |
| 78 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.18634595 |
| 79 | granulocyte differentiation (GO:0030851) | 3.17559706 |
| 80 | radial glial cell differentiation (GO:0060019) | 3.16868323 |
| 81 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.15282510 |
| 82 | regulation of histone H3-K27 methylation (GO:0061085) | 3.13877249 |
| 83 | regulation of tolerance induction (GO:0002643) | 3.13649349 |
| 84 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.13640518 |
| 85 | negative regulation of adaptive immune response (GO:0002820) | 3.11574860 |
| 86 | positive regulation of isotype switching (GO:0045830) | 3.06662679 |
| 87 | positive regulation by host of viral transcription (GO:0043923) | 3.05937513 |
| 88 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.03620711 |
| 89 | T-helper cell differentiation (GO:0042093) | 3.03620711 |
| 90 | regulation of interleukin-13 production (GO:0032656) | 3.03419272 |
| 91 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.02428416 |
| 92 | T cell activation (GO:0042110) | 3.01867286 |
| 93 | negative regulation of T cell apoptotic process (GO:0070233) | 2.98984171 |
| 94 | regulation of interleukin-5 production (GO:0032674) | 2.97989724 |
| 95 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.97923401 |
| 96 | somatic cell DNA recombination (GO:0016444) | 2.97923401 |
| 97 | regulation of defense response to virus by virus (GO:0050690) | 2.97804176 |
| 98 | establishment of protein localization to Golgi (GO:0072600) | 2.95323833 |
| 99 | cellular extravasation (GO:0045123) | 2.93971655 |
| 100 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.90582630 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.33901662 |
| 2 | RUNX_20019798_ChIP-Seq_JUKART_Human | 5.53389738 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.37497647 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.29150156 |
| 5 | MYC_22102868_ChIP-Seq_BL_Human | 4.21869723 |
| 6 | UTX_26944678_Chip-Seq_JUKART_Human | 3.60886578 |
| 7 | MYB_26560356_Chip-Seq_TH2_Human | 3.56661851 |
| 8 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.46561093 |
| 9 | GATA3_27048872_Chip-Seq_THYMUS_Human | 3.44212550 |
| 10 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.06589162 |
| 11 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.03456951 |
| 12 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.86551782 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.79505882 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.77921419 |
| 15 | MYB_26560356_Chip-Seq_TH1_Human | 2.67457660 |
| 16 | MAF_26560356_Chip-Seq_TH1_Human | 2.60614593 |
| 17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.58190442 |
| 18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.57711214 |
| 19 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.55150558 |
| 20 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.50811903 |
| 21 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.42131652 |
| 22 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.39115014 |
| 23 | MAF_26560356_Chip-Seq_TH2_Human | 2.24601009 |
| 24 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.20874690 |
| 25 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.13972275 |
| 26 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.11041802 |
| 27 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.04624979 |
| 28 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 2.04218869 |
| 29 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.00363643 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.98287041 |
| 31 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.98171461 |
| 32 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.97683537 |
| 33 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.96981843 |
| 34 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.91077650 |
| 35 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.90345143 |
| 36 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.87471637 |
| 37 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.86735415 |
| 38 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.79472813 |
| 39 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.75388138 |
| 40 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.75175827 |
| 41 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69603228 |
| 42 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60790470 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59525323 |
| 44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.59073223 |
| 45 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.56888791 |
| 46 | GATA3_26560356_Chip-Seq_TH2_Human | 1.55406540 |
| 47 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.54660612 |
| 48 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.51497795 |
| 49 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.50806926 |
| 50 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50304426 |
| 51 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.47770245 |
| 52 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.45061804 |
| 53 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.41509291 |
| 54 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.39368555 |
| 55 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.39215759 |
| 56 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.36085611 |
| 57 | SPI1_23127762_ChIP-Seq_K562_Human | 1.34349458 |
| 58 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.29034057 |
| 59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28836229 |
| 60 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.28067748 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.19620446 |
| 62 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.16315346 |
| 63 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.13503839 |
| 64 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.13075574 |
| 65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.09734558 |
| 66 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.06717099 |
| 67 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.04570929 |
| 68 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.04153146 |
| 69 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02770228 |
| 70 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.01584144 |
| 71 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99393880 |
| 72 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.97952532 |
| 73 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.97052117 |
| 74 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.94711198 |
| 75 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94400853 |
| 76 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93749292 |
| 77 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.93602168 |
| 78 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92527494 |
| 79 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.91000367 |
| 80 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.86686408 |
| 81 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84607622 |
| 82 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84357686 |
| 83 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.82438101 |
| 84 | GATA3_26560356_Chip-Seq_TH1_Human | 0.82409483 |
| 85 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.80407135 |
| 86 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.80254074 |
| 87 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.80149636 |
| 88 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.79884212 |
| 89 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.79494374 |
| 90 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.78508533 |
| 91 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.78268510 |
| 92 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.76503178 |
| 93 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75666508 |
| 94 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.74169798 |
| 95 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.73781721 |
| 96 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.72514697 |
| 97 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.71777137 |
| 98 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.70492093 |
| 99 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.69760348 |
| 100 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.69033260 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 6.87076047 |
| 2 | MP0000685_abnormal_immune_system | 4.20073974 |
| 3 | MP0005671_abnormal_response_to | 3.86690760 |
| 4 | MP0000703_abnormal_thymus_morphology | 3.37977417 |
| 5 | MP0002396_abnormal_hematopoietic_system | 3.30555509 |
| 6 | MP0004381_abnormal_hair_follicle | 3.20797192 |
| 7 | MP0009333_abnormal_splenocyte_physiolog | 2.99326297 |
| 8 | MP0001800_abnormal_humoral_immune | 2.93825651 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.93264093 |
| 10 | MP0003183_abnormal_peptide_metabolism | 2.83650551 |
| 11 | MP0002398_abnormal_bone_marrow | 2.76076869 |
| 12 | MP0002405_respiratory_system_inflammati | 2.69732666 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.62498426 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.57935253 |
| 15 | MP0001819_abnormal_immune_cell | 2.45565672 |
| 16 | MP0000716_abnormal_immune_system | 2.29214565 |
| 17 | MP0003436_decreased_susceptibility_to | 2.28693668 |
| 18 | MP0002722_abnormal_immune_system | 2.27139536 |
| 19 | MP0002723_abnormal_immune_serum | 2.25631501 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.17353465 |
| 21 | MP0005075_abnormal_melanosome_morpholog | 2.15804604 |
| 22 | MP0001790_abnormal_immune_system | 2.15500767 |
| 23 | MP0005387_immune_system_phenotype | 2.15500767 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 2.14950171 |
| 25 | MP0008877_abnormal_DNA_methylation | 2.08307126 |
| 26 | MP0009278_abnormal_bone_marrow | 2.06978958 |
| 27 | MP0003300_gastrointestinal_ulcer | 2.05964348 |
| 28 | MP0008057_abnormal_DNA_replication | 1.99951202 |
| 29 | MP0000689_abnormal_spleen_morphology | 1.98691507 |
| 30 | MP0004947_skin_inflammation | 1.97743964 |
| 31 | MP0003724_increased_susceptibility_to | 1.86243580 |
| 32 | MP0002429_abnormal_blood_cell | 1.83701741 |
| 33 | MP0005025_abnormal_response_to | 1.83471569 |
| 34 | MP0002009_preneoplasia | 1.81432203 |
| 35 | MP0002163_abnormal_gland_morphology | 1.81081579 |
| 36 | MP0005464_abnormal_platelet_physiology | 1.66091245 |
| 37 | MP0004185_abnormal_adipocyte_glucose | 1.64696901 |
| 38 | MP0001873_stomach_inflammation | 1.61947937 |
| 39 | MP0009785_altered_susceptibility_to | 1.57636188 |
| 40 | MP0003866_abnormal_defecation | 1.55203464 |
| 41 | MP0005310_abnormal_salivary_gland | 1.54216039 |
| 42 | MP0002419_abnormal_innate_immunity | 1.50004981 |
| 43 | MP0010155_abnormal_intestine_physiology | 1.42700207 |
| 44 | MP0002166_altered_tumor_susceptibility | 1.42478536 |
| 45 | MP0000678_abnormal_parathyroid_gland | 1.31179133 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.29259698 |
| 47 | MP0000465_gastrointestinal_hemorrhage | 1.28913700 |
| 48 | MP0004808_abnormal_hematopoietic_stem | 1.16112406 |
| 49 | MP0005451_abnormal_body_composition | 1.12296677 |
| 50 | MP0003787_abnormal_imprinting | 1.01077066 |
| 51 | MP0004130_abnormal_muscle_cell | 1.00652539 |
| 52 | MP0000490_abnormal_crypts_of | 1.00402428 |
| 53 | MP0003303_peritoneal_inflammation | 0.98185352 |
| 54 | MP0002019_abnormal_tumor_incidence | 0.95957645 |
| 55 | MP0004019_abnormal_vitamin_homeostasis | 0.95407312 |
| 56 | MP0002877_abnormal_melanocyte_morpholog | 0.94451246 |
| 57 | MP0002006_tumorigenesis | 0.93801141 |
| 58 | MP0001919_abnormal_reproductive_system | 0.93055837 |
| 59 | MP0003959_abnormal_lean_body | 0.89519291 |
| 60 | MP0010094_abnormal_chromosome_stability | 0.89470225 |
| 61 | MP0008961_abnormal_basal_metabolism | 0.88095640 |
| 62 | MP0001853_heart_inflammation | 0.87308343 |
| 63 | MP0005666_abnormal_adipose_tissue | 0.84985906 |
| 64 | MP0008469_abnormal_protein_level | 0.83742655 |
| 65 | MP0008995_early_reproductive_senescence | 0.83406983 |
| 66 | MP0005166_decreased_susceptibility_to | 0.82901640 |
| 67 | MP0001348_abnormal_lacrimal_gland | 0.81986110 |
| 68 | MP0000858_altered_metastatic_potential | 0.81443132 |
| 69 | MP0002127_abnormal_cardiovascular_syste | 0.80090386 |
| 70 | MP0001545_abnormal_hematopoietic_system | 0.79820169 |
| 71 | MP0005397_hematopoietic_system_phenotyp | 0.79820169 |
| 72 | MP0005379_endocrine/exocrine_gland_phen | 0.78967878 |
| 73 | MP0002933_joint_inflammation | 0.78593233 |
| 74 | MP0002909_abnormal_adrenal_gland | 0.74443627 |
| 75 | MP0009763_increased_sensitivity_to | 0.72481927 |
| 76 | MP0006082_CNS_inflammation | 0.71743360 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.71345985 |
| 78 | MP0001730_embryonic_growth_arrest | 0.70702001 |
| 79 | MP0001851_eye_inflammation | 0.62421123 |
| 80 | MP0002138_abnormal_hepatobiliary_system | 0.60952901 |
| 81 | MP0001533_abnormal_skeleton_physiology | 0.60785584 |
| 82 | MP0000313_abnormal_cell_death | 0.60628605 |
| 83 | MP0004264_abnormal_extraembryonic_tissu | 0.57139180 |
| 84 | MP0008260_abnormal_autophagy | 0.55100951 |
| 85 | MP0000350_abnormal_cell_proliferation | 0.53760462 |
| 86 | MP0003111_abnormal_nucleus_morphology | 0.53470612 |
| 87 | MP0005645_abnormal_hypothalamus_physiol | 0.53048308 |
| 88 | MP0003172_abnormal_lysosome_physiology | 0.52387152 |
| 89 | MP0003045_fibrosis | 0.51204579 |
| 90 | MP0002693_abnormal_pancreas_physiology | 0.50489917 |
| 91 | MP0009697_abnormal_copulation | 0.49213900 |
| 92 | MP0009765_abnormal_xenobiotic_induced | 0.45319915 |
| 93 | MP0003786_premature_aging | 0.44408546 |
| 94 | MP0002970_abnormal_white_adipose | 0.44052150 |
| 95 | MP0003191_abnormal_cellular_cholesterol | 0.39874148 |
| 96 | MP0000920_abnormal_myelination | 0.38521764 |
| 97 | MP0003077_abnormal_cell_cycle | 0.37398228 |
| 98 | MP0001666_abnormal_nutrient_absorption | 0.37332901 |
| 99 | MP0001765_abnormal_ion_homeostasis | 0.36517145 |
| 100 | MP0005389_reproductive_system_phenotype | 0.36057359 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.47801937 |
| 2 | Severe combined immunodeficiency (HP:0004430) | 6.40335886 |
| 3 | Abnormality of T cell number (HP:0011839) | 6.13786131 |
| 4 | Chronic diarrhea (HP:0002028) | 5.97299628 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 5.94261338 |
| 6 | Panhypogammaglobulinemia (HP:0003139) | 5.44374911 |
| 7 | Increased IgM level (HP:0003496) | 5.28533880 |
| 8 | Combined immunodeficiency (HP:0005387) | 5.21725407 |
| 9 | Lymphopenia (HP:0001888) | 4.73423627 |
| 10 | Abnormality of B cell number (HP:0010975) | 4.67383014 |
| 11 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 4.59857931 |
| 12 | Abnormality of T cells (HP:0002843) | 4.57763491 |
| 13 | B lymphocytopenia (HP:0010976) | 4.50579225 |
| 14 | IgA deficiency (HP:0002720) | 4.39880901 |
| 15 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.17983823 |
| 16 | Hypoplasia of the thymus (HP:0000778) | 4.08701520 |
| 17 | Gastrointestinal stroma tumor (HP:0100723) | 4.06525733 |
| 18 | Granulocytopenia (HP:0001913) | 4.04194906 |
| 19 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.97797902 |
| 20 | Recurrent viral infections (HP:0004429) | 3.93807085 |
| 21 | IgG deficiency (HP:0004315) | 3.80147270 |
| 22 | Recurrent fungal infections (HP:0002841) | 3.77770670 |
| 23 | Eosinophilia (HP:0001880) | 3.76541583 |
| 24 | Eczematoid dermatitis (HP:0000976) | 3.69558689 |
| 25 | Autoimmune thrombocytopenia (HP:0001973) | 3.64396080 |
| 26 | Thyroiditis (HP:0100646) | 3.64084283 |
| 27 | Lymphoma (HP:0002665) | 3.52826428 |
| 28 | Increased IgE level (HP:0003212) | 3.52336736 |
| 29 | Abnormality of eosinophils (HP:0001879) | 3.49080580 |
| 30 | Encephalitis (HP:0002383) | 3.47620691 |
| 31 | Stomatitis (HP:0010280) | 3.47166087 |
| 32 | Vasculitis (HP:0002633) | 3.39543448 |
| 33 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 3.16909929 |
| 34 | Hypergammaglobulinemia (HP:0010702) | 3.09860547 |
| 35 | Prostate neoplasm (HP:0100787) | 3.02694198 |
| 36 | Meningitis (HP:0001287) | 3.01079147 |
| 37 | Leukocytosis (HP:0001974) | 2.93283144 |
| 38 | Spontaneous hematomas (HP:0007420) | 2.92810573 |
| 39 | Abnormality of T cell physiology (HP:0011840) | 2.83216483 |
| 40 | Abnormality of the fingertips (HP:0001211) | 2.79997630 |
| 41 | Agammaglobulinemia (HP:0004432) | 2.70195451 |
| 42 | Viral hepatitis (HP:0006562) | 2.70067721 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.68460713 |
| 44 | Abnormality of the thymus (HP:0000777) | 2.67781247 |
| 45 | Pustule (HP:0200039) | 2.53744443 |
| 46 | Subacute progressive viral hepatitis (HP:0006572) | 2.51557365 |
| 47 | Acute hepatic failure (HP:0006554) | 2.50676841 |
| 48 | Papilloma (HP:0012740) | 2.50205452 |
| 49 | Verrucae (HP:0200043) | 2.50205452 |
| 50 | Chronic obstructive pulmonary disease (HP:0006510) | 2.49966681 |
| 51 | Obstructive lung disease (HP:0006536) | 2.49966681 |
| 52 | Prolonged bleeding time (HP:0003010) | 2.46094655 |
| 53 | Slow saccadic eye movements (HP:0000514) | 2.45818227 |
| 54 | Recurrent bronchitis (HP:0002837) | 2.44704509 |
| 55 | Myositis (HP:0100614) | 2.36083364 |
| 56 | Basal cell carcinoma (HP:0002671) | 2.35787879 |
| 57 | Abnormality of the columella (HP:0009929) | 2.32855335 |
| 58 | Recurrent cutaneous fungal infections (HP:0011370) | 2.29356641 |
| 59 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.29356641 |
| 60 | Gastrointestinal inflammation (HP:0004386) | 2.27495132 |
| 61 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.26393797 |
| 62 | Subaortic stenosis (HP:0001682) | 2.26393797 |
| 63 | Seborrheic dermatitis (HP:0001051) | 2.24385540 |
| 64 | Aplastic anemia (HP:0001915) | 2.24179517 |
| 65 | IgM deficiency (HP:0002850) | 2.23757197 |
| 66 | Hepatitis (HP:0012115) | 2.21580990 |
| 67 | Joint swelling (HP:0001386) | 2.20680122 |
| 68 | Prominent nose (HP:0000448) | 2.19646422 |
| 69 | Emphysema (HP:0002097) | 2.11175920 |
| 70 | Pancytopenia (HP:0001876) | 2.09335760 |
| 71 | Epistaxis (HP:0000421) | 2.07245563 |
| 72 | Inflammation of the large intestine (HP:0002037) | 2.05969752 |
| 73 | Broad face (HP:0000283) | 2.04498467 |
| 74 | Trigonocephaly (HP:0000243) | 2.03447998 |
| 75 | Fatigue (HP:0012378) | 1.99841474 |
| 76 | Hypochromic anemia (HP:0001931) | 1.99568057 |
| 77 | Dysmetric saccades (HP:0000641) | 1.99562427 |
| 78 | Papilledema (HP:0001085) | 1.97053485 |
| 79 | High anterior hairline (HP:0009890) | 1.95261511 |
| 80 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.94289038 |
| 81 | Abnormality of male internal genitalia (HP:0000022) | 1.87526601 |
| 82 | Chest pain (HP:0100749) | 1.82645756 |
| 83 | Cutis marmorata (HP:0000965) | 1.80814393 |
| 84 | Amaurosis fugax (HP:0100576) | 1.79886159 |
| 85 | Micronodular cirrhosis (HP:0001413) | 1.79506566 |
| 86 | Somatic mutation (HP:0001428) | 1.79364109 |
| 87 | Bicuspid aortic valve (HP:0001647) | 1.77428723 |
| 88 | Menstrual irregularities (HP:0000858) | 1.75361585 |
| 89 | Abnormality of macrophages (HP:0004311) | 1.75186342 |
| 90 | Mediastinal lymphadenopathy (HP:0100721) | 1.74482435 |
| 91 | Recurrent abscess formation (HP:0002722) | 1.74437249 |
| 92 | Restrictive lung disease (HP:0002091) | 1.74342490 |
| 93 | Pulmonary embolism (HP:0002204) | 1.73082106 |
| 94 | Neoplasm of the adrenal cortex (HP:0100641) | 1.71478196 |
| 95 | Stomach cancer (HP:0012126) | 1.70949396 |
| 96 | Leukopenia (HP:0001882) | 1.69318008 |
| 97 | Optic nerve coloboma (HP:0000588) | 1.69253470 |
| 98 | Easy fatigability (HP:0003388) | 1.67359733 |
| 99 | Gastrointestinal infarctions (HP:0005244) | 1.67274153 |
| 100 | Deep palmar crease (HP:0006191) | 1.66841286 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EEF2K | 4.82154980 |
| 2 | PRPF4B | 4.22766733 |
| 3 | MAP4K1 | 3.96358927 |
| 4 | SCYL2 | 3.61806731 |
| 5 | NLK | 3.32585777 |
| 6 | TXK | 3.05196676 |
| 7 | ITK | 2.56419853 |
| 8 | MAP3K10 | 2.42770920 |
| 9 | CAMKK1 | 2.40682031 |
| 10 | GRK6 | 2.31636759 |
| 11 | ZAP70 | 2.25865103 |
| 12 | CAMKK2 | 2.02943429 |
| 13 | PASK | 2.01473286 |
| 14 | FES | 1.93681561 |
| 15 | TRIB3 | 1.89179887 |
| 16 | MAP3K7 | 1.83463692 |
| 17 | SYK | 1.81558983 |
| 18 | CDK12 | 1.76187443 |
| 19 | TYK2 | 1.70499462 |
| 20 | BTK | 1.67896582 |
| 21 | TAOK3 | 1.65179151 |
| 22 | PIK3CG | 1.64132682 |
| 23 | MAPK11 | 1.59652482 |
| 24 | SMG1 | 1.59495111 |
| 25 | FGFR2 | 1.58384610 |
| 26 | MARK2 | 1.51727660 |
| 27 | MAP3K13 | 1.51671995 |
| 28 | RIPK4 | 1.38592741 |
| 29 | LCK | 1.38590803 |
| 30 | TEC | 1.30498192 |
| 31 | CSK | 1.25180865 |
| 32 | PRKCQ | 1.21037992 |
| 33 | CDK4 | 1.12406004 |
| 34 | HCK | 1.10852566 |
| 35 | MAPK12 | 1.07041470 |
| 36 | CDK6 | 1.05423193 |
| 37 | FGFR3 | 1.04678890 |
| 38 | TYRO3 | 1.04282445 |
| 39 | FGFR4 | 1.04175663 |
| 40 | SIK3 | 1.00155622 |
| 41 | PKN2 | 1.00005199 |
| 42 | LYN | 0.98583367 |
| 43 | CSF1R | 0.97660549 |
| 44 | TNK2 | 0.97142711 |
| 45 | PRKD3 | 0.93969939 |
| 46 | IRAK4 | 0.91724227 |
| 47 | CDK9 | 0.90463647 |
| 48 | MAP3K14 | 0.87549160 |
| 49 | HIPK2 | 0.87045700 |
| 50 | TBK1 | 0.84473090 |
| 51 | IKBKE | 0.84152081 |
| 52 | NTRK2 | 0.82312122 |
| 53 | LRRK2 | 0.82297719 |
| 54 | PDK1 | 0.78305596 |
| 55 | JAK3 | 0.76922871 |
| 56 | MAPK4 | 0.76538329 |
| 57 | VRK2 | 0.73705872 |
| 58 | MST4 | 0.71909704 |
| 59 | TAF1 | 0.69022942 |
| 60 | TESK2 | 0.67905894 |
| 61 | CAMK1 | 0.65120823 |
| 62 | FGR | 0.64860331 |
| 63 | ICK | 0.63776585 |
| 64 | BRD4 | 0.62949575 |
| 65 | TRPM7 | 0.62403768 |
| 66 | CLK1 | 0.60816956 |
| 67 | CDK7 | 0.59138326 |
| 68 | JAK1 | 0.57290535 |
| 69 | MAPKAPK5 | 0.54446194 |
| 70 | MAPK7 | 0.53103869 |
| 71 | PRKCH | 0.51631089 |
| 72 | CAMK4 | 0.49592400 |
| 73 | BLK | 0.48940941 |
| 74 | TAOK2 | 0.47678714 |
| 75 | MAP2K3 | 0.47082474 |
| 76 | SIK1 | 0.46720442 |
| 77 | IRAK1 | 0.44559099 |
| 78 | IKBKB | 0.43129959 |
| 79 | MAP3K11 | 0.42789740 |
| 80 | STK10 | 0.42477688 |
| 81 | PDGFRB | 0.41314188 |
| 82 | CDK8 | 0.39878042 |
| 83 | FYN | 0.39678056 |
| 84 | MARK3 | 0.39657279 |
| 85 | KDR | 0.38077394 |
| 86 | NEK6 | 0.37537751 |
| 87 | RET | 0.36322152 |
| 88 | MAP3K3 | 0.35447149 |
| 89 | ATR | 0.33378109 |
| 90 | MAP2K2 | 0.32862074 |
| 91 | EIF2AK2 | 0.32343511 |
| 92 | RPS6KB2 | 0.31899067 |
| 93 | MAPK3 | 0.31267043 |
| 94 | SRPK1 | 0.30652907 |
| 95 | MAP3K1 | 0.30546647 |
| 96 | SIK2 | 0.30103872 |
| 97 | MAPKAPK2 | 0.25154118 |
| 98 | PTK6 | 0.22943867 |
| 99 | MAPK13 | 0.21716482 |
| 100 | NEK9 | 0.20965290 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 5.86809299 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.45985827 |
| 3 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.88607091 |
| 4 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.69529895 |
| 5 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.53198268 |
| 6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.47129811 |
| 7 | Thyroid cancer_Homo sapiens_hsa05216 | 2.38047686 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.37129688 |
| 9 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 2.09951139 |
| 10 | Endometrial cancer_Homo sapiens_hsa05213 | 1.91634188 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.76575830 |
| 12 | Colorectal cancer_Homo sapiens_hsa05210 | 1.74589912 |
| 13 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.67370008 |
| 14 | Allograft rejection_Homo sapiens_hsa05330 | 1.65730924 |
| 15 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.56477556 |
| 16 | Ribosome_Homo sapiens_hsa03010 | 1.55347353 |
| 17 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.53399296 |
| 18 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.50985745 |
| 19 | DNA replication_Homo sapiens_hsa03030 | 1.42033497 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.38396877 |
| 21 | Prostate cancer_Homo sapiens_hsa05215 | 1.35702763 |
| 22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.31747436 |
| 23 | Hepatitis B_Homo sapiens_hsa05161 | 1.31689156 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.30148977 |
| 25 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.27183261 |
| 26 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.22536078 |
| 27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.17099719 |
| 28 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.13848063 |
| 29 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.11747720 |
| 30 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.09370848 |
| 31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.07748910 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.07429605 |
| 33 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.07260671 |
| 34 | Glioma_Homo sapiens_hsa05214 | 1.06765341 |
| 35 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.06736341 |
| 36 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.06446888 |
| 37 | Platelet activation_Homo sapiens_hsa04611 | 1.06145934 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.01743241 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.01587420 |
| 40 | Cell cycle_Homo sapiens_hsa04110 | 1.00628471 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.99754170 |
| 42 | Malaria_Homo sapiens_hsa05144 | 0.98789807 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.96299816 |
| 44 | HTLV-I infection_Homo sapiens_hsa05166 | 0.93018861 |
| 45 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.91018820 |
| 46 | Legionellosis_Homo sapiens_hsa05134 | 0.90698167 |
| 47 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.89927464 |
| 48 | Viral myocarditis_Homo sapiens_hsa05416 | 0.88746600 |
| 49 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.85798314 |
| 50 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.85560058 |
| 51 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.85481069 |
| 52 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.85258730 |
| 53 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.83989540 |
| 54 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.82932051 |
| 55 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.74772012 |
| 56 | Apoptosis_Homo sapiens_hsa04210 | 0.71223067 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.66826100 |
| 58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.66687912 |
| 59 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.66036256 |
| 60 | Influenza A_Homo sapiens_hsa05164 | 0.64727046 |
| 61 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.63296596 |
| 62 | Long-term potentiation_Homo sapiens_hsa04720 | 0.62709430 |
| 63 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.62289235 |
| 64 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.55567885 |
| 65 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.54862801 |
| 66 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54458595 |
| 67 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.53492504 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52952251 |
| 69 | Adherens junction_Homo sapiens_hsa04520 | 0.51122450 |
| 70 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.50998776 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50901125 |
| 72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49292042 |
| 73 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.48303516 |
| 74 | Base excision repair_Homo sapiens_hsa03410 | 0.45424223 |
| 75 | Shigellosis_Homo sapiens_hsa05131 | 0.44799461 |
| 76 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.44265856 |
| 77 | Tuberculosis_Homo sapiens_hsa05152 | 0.42926635 |
| 78 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.42291506 |
| 79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41949604 |
| 80 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.41044604 |
| 81 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.39826176 |
| 82 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.39669808 |
| 83 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.37246531 |
| 84 | Hepatitis C_Homo sapiens_hsa05160 | 0.35984385 |
| 85 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.35352769 |
| 86 | Homologous recombination_Homo sapiens_hsa03440 | 0.34932798 |
| 87 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.34845161 |
| 88 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.33852417 |
| 89 | RNA transport_Homo sapiens_hsa03013 | 0.33555137 |
| 90 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.32810888 |
| 91 | Mismatch repair_Homo sapiens_hsa03430 | 0.32611437 |
| 92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.31455800 |
| 93 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.30083001 |
| 94 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.30071339 |
| 95 | Lysine degradation_Homo sapiens_hsa00310 | 0.29392914 |
| 96 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.28865891 |
| 97 | Melanoma_Homo sapiens_hsa05218 | 0.28835975 |
| 98 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28720506 |
| 99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.27384000 |
| 100 | Melanogenesis_Homo sapiens_hsa04916 | 0.25038841 |

