

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 8.72035314 |
| 2 | T cell migration (GO:0072678) | 7.06131704 |
| 3 | negative T cell selection (GO:0043383) | 6.35774669 |
| 4 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.74211056 |
| 5 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.71296055 |
| 6 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.60105670 |
| 7 | positive T cell selection (GO:0043368) | 5.48544386 |
| 8 | negative thymic T cell selection (GO:0045060) | 5.46582678 |
| 9 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.40536601 |
| 10 | negative regulation of cell killing (GO:0031342) | 5.36648603 |
| 11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.36648603 |
| 12 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.31469565 |
| 13 | cytidine metabolic process (GO:0046087) | 5.22411214 |
| 14 | cytidine catabolic process (GO:0006216) | 5.22411214 |
| 15 | cytidine deamination (GO:0009972) | 5.22411214 |
| 16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.11661576 |
| 17 | negative regulation of execution phase of apoptosis (GO:1900118) | 5.08642834 |
| 18 | cellular response to interleukin-15 (GO:0071350) | 5.08629743 |
| 19 | T cell selection (GO:0045058) | 5.01929123 |
| 20 | response to interleukin-15 (GO:0070672) | 4.92447792 |
| 21 | positive thymic T cell selection (GO:0045059) | 4.91074982 |
| 22 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.89264173 |
| 23 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.89264173 |
| 24 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.73455979 |
| 25 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.70349087 |
| 26 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.69343121 |
| 27 | lymphocyte chemotaxis (GO:0048247) | 4.67233620 |
| 28 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.60869344 |
| 29 | thymic T cell selection (GO:0045061) | 4.60279925 |
| 30 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.57998843 |
| 31 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.35233730 |
| 32 | DNA deamination (GO:0045006) | 4.31999405 |
| 33 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.30762669 |
| 34 | regulation of regulatory T cell differentiation (GO:0045589) | 4.23052105 |
| 35 | tolerance induction (GO:0002507) | 4.22508447 |
| 36 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.21615178 |
| 37 | T cell mediated immunity (GO:0002456) | 4.19160389 |
| 38 | regulation of T cell tolerance induction (GO:0002664) | 4.18177958 |
| 39 | positive regulation of B cell differentiation (GO:0045579) | 4.15055384 |
| 40 | lymphocyte migration (GO:0072676) | 4.12061308 |
| 41 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.09508762 |
| 42 | leukocyte aggregation (GO:0070486) | 4.02358277 |
| 43 | regulation of defense response to virus by virus (GO:0050690) | 4.02215007 |
| 44 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.98435196 |
| 45 | positive regulation of lamellipodium assembly (GO:0010592) | 3.91295188 |
| 46 | regulation of gamma-delta T cell activation (GO:0046643) | 3.89904889 |
| 47 | cytolysis (GO:0019835) | 3.89899593 |
| 48 | T cell receptor signaling pathway (GO:0050852) | 3.85172011 |
| 49 | sequestering of actin monomers (GO:0042989) | 3.79159499 |
| 50 | chemokine-mediated signaling pathway (GO:0070098) | 3.78761454 |
| 51 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.77974483 |
| 52 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.77712734 |
| 53 | regulation of B cell differentiation (GO:0045577) | 3.73760853 |
| 54 | negative regulation of T cell apoptotic process (GO:0070233) | 3.72563498 |
| 55 | positive regulation of tolerance induction (GO:0002645) | 3.71981187 |
| 56 | negative regulation of phagocytosis (GO:0050765) | 3.67735564 |
| 57 | respiratory burst (GO:0045730) | 3.66075424 |
| 58 | positive regulation of T cell chemotaxis (GO:0010820) | 3.65444677 |
| 59 | regulation of T cell chemotaxis (GO:0010819) | 3.65444677 |
| 60 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.63679003 |
| 61 | negative regulation of type 2 immune response (GO:0002829) | 3.60216709 |
| 62 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.58152445 |
| 63 | immunoglobulin mediated immune response (GO:0016064) | 3.58027214 |
| 64 | positive regulation of cell killing (GO:0031343) | 3.53359414 |
| 65 | regulation of tolerance induction (GO:0002643) | 3.52835077 |
| 66 | dendritic cell chemotaxis (GO:0002407) | 3.51504094 |
| 67 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.50716269 |
| 68 | cellular defense response (GO:0006968) | 3.50667411 |
| 69 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.50179881 |
| 70 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.50166529 |
| 71 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.45414758 |
| 72 | negative regulation of T cell mediated immunity (GO:0002710) | 3.40309849 |
| 73 | positive regulation of granulocyte differentiation (GO:0030854) | 3.40250083 |
| 74 | natural killer cell differentiation (GO:0001779) | 3.39716190 |
| 75 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.36150961 |
| 76 | muscle atrophy (GO:0014889) | 3.34642276 |
| 77 | regulation of cell killing (GO:0031341) | 3.34197751 |
| 78 | negative regulation of stress fiber assembly (GO:0051497) | 3.33063078 |
| 79 | regulation of calcium-mediated signaling (GO:0050848) | 3.31902420 |
| 80 | T cell costimulation (GO:0031295) | 3.31668247 |
| 81 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.27836119 |
| 82 | lymphocyte costimulation (GO:0031294) | 3.27477586 |
| 83 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.25585392 |
| 84 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.19986539 |
| 85 | positive regulation of T cell migration (GO:2000406) | 3.18930577 |
| 86 | B cell receptor signaling pathway (GO:0050853) | 3.18461904 |
| 87 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.13913707 |
| 88 | regulation of activation of Janus kinase activity (GO:0010533) | 3.10678924 |
| 89 | activated T cell proliferation (GO:0050798) | 3.09765526 |
| 90 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.08708287 |
| 91 | positive regulation of lymphocyte migration (GO:2000403) | 3.07494939 |
| 92 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.06699834 |
| 93 | dendritic cell migration (GO:0036336) | 3.06269640 |
| 94 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.06249947 |
| 95 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.04297018 |
| 96 | B cell mediated immunity (GO:0019724) | 3.03109726 |
| 97 | positive regulation of interleukin-4 production (GO:0032753) | 3.02519911 |
| 98 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.01758516 |
| 99 | positive regulation of interleukin-17 production (GO:0032740) | 2.98801124 |
| 100 | positive regulation of lamellipodium organization (GO:1902745) | 2.97738477 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.21038776 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.87581953 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.24839222 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.95564527 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.57128020 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.50206948 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.51419740 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.36425292 |
| 9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.33529807 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 3.23587916 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.04510792 |
| 12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.92568994 |
| 13 | UTX_26944678_Chip-Seq_JUKART_Human | 2.89586428 |
| 14 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.79242811 |
| 15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.78784630 |
| 16 | MYB_26560356_Chip-Seq_TH1_Human | 2.70003832 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.56621158 |
| 18 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.56105094 |
| 19 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.51649652 |
| 20 | MAF_26560356_Chip-Seq_TH1_Human | 2.41830489 |
| 21 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.31752042 |
| 22 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.22651183 |
| 23 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.19463308 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.13284156 |
| 25 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.10175173 |
| 26 | MAF_26560356_Chip-Seq_TH2_Human | 2.06339495 |
| 27 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 2.01679951 |
| 28 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.00749085 |
| 29 | GATA3_26560356_Chip-Seq_TH2_Human | 1.95101438 |
| 30 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.75482963 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.74770326 |
| 32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.69853199 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.66709766 |
| 34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.65759869 |
| 35 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.65377512 |
| 36 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.60672688 |
| 37 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56733911 |
| 38 | SPI1_23127762_ChIP-Seq_K562_Human | 1.56538974 |
| 39 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.54085520 |
| 40 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.53905818 |
| 41 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.52495789 |
| 42 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.51375732 |
| 43 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.48631017 |
| 44 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.44809584 |
| 45 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43837840 |
| 46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.43759598 |
| 47 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.42519663 |
| 48 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.34840144 |
| 49 | MYC_22102868_ChIP-Seq_BL_Human | 1.30876521 |
| 50 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.27538729 |
| 51 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.21487296 |
| 52 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19574464 |
| 53 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.18299442 |
| 54 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.16809707 |
| 55 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14309373 |
| 56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.12785381 |
| 57 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.11916501 |
| 58 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.10643144 |
| 59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09863270 |
| 60 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.08373492 |
| 61 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07869176 |
| 62 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.07549815 |
| 63 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05816273 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.02986278 |
| 65 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.02605603 |
| 66 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01138920 |
| 67 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.97522789 |
| 68 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.94792598 |
| 69 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94178054 |
| 70 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.93923551 |
| 71 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.90444458 |
| 72 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90410735 |
| 73 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.87686961 |
| 74 | GATA3_26560356_Chip-Seq_TH1_Human | 0.86310526 |
| 75 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.85994536 |
| 76 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85144240 |
| 77 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.84824987 |
| 78 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.84080319 |
| 79 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.83705964 |
| 80 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.81707274 |
| 81 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.81419827 |
| 82 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.79299083 |
| 83 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.78721873 |
| 84 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.77644357 |
| 85 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.76041572 |
| 86 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.75118716 |
| 87 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73000509 |
| 88 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.72385749 |
| 89 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.71934799 |
| 90 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.71881891 |
| 91 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.71843790 |
| 92 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70249621 |
| 93 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.69706130 |
| 94 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.69243146 |
| 95 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.68828099 |
| 96 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.67439166 |
| 97 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.67018485 |
| 98 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.66807915 |
| 99 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.66706049 |
| 100 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.66545769 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.86673274 |
| 2 | MP0009785_altered_susceptibility_to | 3.97691933 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.70857491 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.70786539 |
| 5 | MP0000685_abnormal_immune_system | 3.10382114 |
| 6 | MP0001800_abnormal_humoral_immune | 3.07451771 |
| 7 | MP0001790_abnormal_immune_system | 3.00470826 |
| 8 | MP0005387_immune_system_phenotype | 3.00470826 |
| 9 | MP0002166_altered_tumor_susceptibility | 2.99923393 |
| 10 | MP0005025_abnormal_response_to | 2.96966173 |
| 11 | MP0003724_increased_susceptibility_to | 2.96847274 |
| 12 | MP0005000_abnormal_immune_tolerance | 2.96495805 |
| 13 | MP0003866_abnormal_defecation | 2.83838778 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.79866106 |
| 15 | MP0001819_abnormal_immune_cell | 2.71442393 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 2.70518245 |
| 17 | MP0002723_abnormal_immune_serum | 2.53591531 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 2.46802433 |
| 19 | MP0003436_decreased_susceptibility_to | 2.46668192 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.40291406 |
| 21 | MP0006082_CNS_inflammation | 2.31222104 |
| 22 | MP0003045_fibrosis | 2.28847086 |
| 23 | MP0002419_abnormal_innate_immunity | 2.25775790 |
| 24 | MP0002398_abnormal_bone_marrow | 2.24624523 |
| 25 | MP0003448_altered_tumor_morphology | 2.21814131 |
| 26 | MP0010155_abnormal_intestine_physiology | 2.21766679 |
| 27 | MP0000703_abnormal_thymus_morphology | 2.19152500 |
| 28 | MP0002405_respiratory_system_inflammati | 2.16867812 |
| 29 | MP0000716_abnormal_immune_system | 2.09924934 |
| 30 | MP0002006_tumorigenesis | 2.05444919 |
| 31 | MP0003011_delayed_dark_adaptation | 1.89955472 |
| 32 | MP0002722_abnormal_immune_system | 1.86976599 |
| 33 | MP0000689_abnormal_spleen_morphology | 1.86856938 |
| 34 | MP0001845_abnormal_inflammatory_respons | 1.78130482 |
| 35 | MP0003300_gastrointestinal_ulcer | 1.75251148 |
| 36 | MP0001873_stomach_inflammation | 1.75216902 |
| 37 | MP0002429_abnormal_blood_cell | 1.64906601 |
| 38 | MP0004947_skin_inflammation | 1.63928145 |
| 39 | MP0005464_abnormal_platelet_physiology | 1.62040583 |
| 40 | MP0002933_joint_inflammation | 1.56357154 |
| 41 | MP0008469_abnormal_protein_level | 1.50621613 |
| 42 | MP0005166_decreased_susceptibility_to | 1.43645488 |
| 43 | MP0000465_gastrointestinal_hemorrhage | 1.43354648 |
| 44 | MP0004381_abnormal_hair_follicle | 1.42071537 |
| 45 | MP0002277_abnormal_respiratory_mucosa | 1.31375829 |
| 46 | MP0000858_altered_metastatic_potential | 1.27502572 |
| 47 | MP0003191_abnormal_cellular_cholesterol | 1.24245053 |
| 48 | MP0000490_abnormal_crypts_of | 1.22120007 |
| 49 | MP0003303_peritoneal_inflammation | 1.21921768 |
| 50 | MP0001533_abnormal_skeleton_physiology | 1.21655074 |
| 51 | MP0002009_preneoplasia | 1.17071268 |
| 52 | MP0009763_increased_sensitivity_to | 1.15235362 |
| 53 | MP0004883_abnormal_blood_vessel | 1.08494438 |
| 54 | MP0000604_amyloidosis | 1.06367534 |
| 55 | MP0001851_eye_inflammation | 1.06228333 |
| 56 | MP0008260_abnormal_autophagy | 0.99675506 |
| 57 | MP0003329_amyloid_beta_deposits | 0.97841980 |
| 58 | MP0005379_endocrine/exocrine_gland_phen | 0.95968824 |
| 59 | MP0008961_abnormal_basal_metabolism | 0.92441243 |
| 60 | MP0002693_abnormal_pancreas_physiology | 0.90727384 |
| 61 | MP0003690_abnormal_glial_cell | 0.86257229 |
| 62 | MP0002019_abnormal_tumor_incidence | 0.83948623 |
| 63 | MP0005075_abnormal_melanosome_morpholog | 0.83804996 |
| 64 | MP0005319_abnormal_enzyme/_coenzyme | 0.83752216 |
| 65 | MP0005310_abnormal_salivary_gland | 0.81899487 |
| 66 | MP0002998_abnormal_bone_remodeling | 0.81524555 |
| 67 | MP0002132_abnormal_respiratory_system | 0.80670417 |
| 68 | MP0005645_abnormal_hypothalamus_physiol | 0.78358476 |
| 69 | MP0009764_decreased_sensitivity_to | 0.76997425 |
| 70 | MP0002138_abnormal_hepatobiliary_system | 0.75592791 |
| 71 | MP0001853_heart_inflammation | 0.74333086 |
| 72 | MP0002396_abnormal_hematopoietic_system | 0.73326930 |
| 73 | MP0004145_abnormal_muscle_electrophysio | 0.73260595 |
| 74 | MP0001542_abnormal_bone_strength | 0.73228894 |
| 75 | MP0002168_other_aberrant_phenotype | 0.71948628 |
| 76 | MP0002139_abnormal_hepatobiliary_system | 0.71818462 |
| 77 | MP0003137_abnormal_impulse_conducting | 0.67412544 |
| 78 | MP0009643_abnormal_urine_homeostasis | 0.66696930 |
| 79 | MP0008873_increased_physiological_sensi | 0.65640643 |
| 80 | MP0005164_abnormal_response_to | 0.55910979 |
| 81 | MP0003183_abnormal_peptide_metabolism | 0.55758843 |
| 82 | MP0000343_altered_response_to | 0.54257482 |
| 83 | MP0000920_abnormal_myelination | 0.49348512 |
| 84 | MP0002163_abnormal_gland_morphology | 0.47966361 |
| 85 | MP0001765_abnormal_ion_homeostasis | 0.47827116 |
| 86 | MP0003868_abnormal_feces_composition | 0.47409904 |
| 87 | MP0003252_abnormal_bile_duct | 0.47336776 |
| 88 | MP0004510_myositis | 0.46568824 |
| 89 | MP0002136_abnormal_kidney_physiology | 0.45670030 |
| 90 | MP0001986_abnormal_taste_sensitivity | 0.44294840 |
| 91 | MP0001727_abnormal_embryo_implantation | 0.44205870 |
| 92 | MP0003795_abnormal_bone_structure | 0.43929064 |
| 93 | MP0003172_abnormal_lysosome_physiology | 0.43170018 |
| 94 | MP0001919_abnormal_reproductive_system | 0.42058629 |
| 95 | MP0000249_abnormal_blood_vessel | 0.41899720 |
| 96 | MP0005058_abnormal_lysosome_morphology | 0.41843543 |
| 97 | MP0009642_abnormal_blood_homeostasis | 0.40078520 |
| 98 | MP0001905_abnormal_dopamine_level | 0.37936543 |
| 99 | MP0001663_abnormal_digestive_system | 0.37418405 |
| 100 | MP0000313_abnormal_cell_death | 0.36156153 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.71491617 |
| 2 | Aplastic anemia (HP:0001915) | 6.59431476 |
| 3 | Abnormality of T cell number (HP:0011839) | 5.94121757 |
| 4 | Increased IgM level (HP:0003496) | 5.38455778 |
| 5 | Stomatitis (HP:0010280) | 5.27138310 |
| 6 | Autoimmune hemolytic anemia (HP:0001890) | 5.18547919 |
| 7 | Spontaneous hematomas (HP:0007420) | 5.13214309 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.03231955 |
| 9 | IgG deficiency (HP:0004315) | 4.86196792 |
| 10 | Acute hepatic failure (HP:0006554) | 4.77984829 |
| 11 | Severe combined immunodeficiency (HP:0004430) | 4.77814830 |
| 12 | Abnormality of T cells (HP:0002843) | 4.60779886 |
| 13 | Chronic diarrhea (HP:0002028) | 4.43079056 |
| 14 | Myositis (HP:0100614) | 4.22311568 |
| 15 | Encephalitis (HP:0002383) | 3.99138287 |
| 16 | Abnormality of macrophages (HP:0004311) | 3.97499880 |
| 17 | Pustule (HP:0200039) | 3.93753440 |
| 18 | Recurrent abscess formation (HP:0002722) | 3.83054913 |
| 19 | Eczematoid dermatitis (HP:0000976) | 3.78768582 |
| 20 | Combined immunodeficiency (HP:0005387) | 3.77579147 |
| 21 | Recurrent bacterial skin infections (HP:0005406) | 3.71057477 |
| 22 | Hypoproteinemia (HP:0003075) | 3.56366857 |
| 23 | Hypergammaglobulinemia (HP:0010702) | 3.55825568 |
| 24 | Recurrent viral infections (HP:0004429) | 3.50038041 |
| 25 | Meningitis (HP:0001287) | 3.39037042 |
| 26 | Thyroiditis (HP:0100646) | 3.29935830 |
| 27 | Recurrent fungal infections (HP:0002841) | 3.27552724 |
| 28 | Pancytopenia (HP:0001876) | 3.18365966 |
| 29 | Recurrent bronchitis (HP:0002837) | 3.07703639 |
| 30 | Panhypogammaglobulinemia (HP:0003139) | 3.06046429 |
| 31 | Abnormality of eosinophils (HP:0001879) | 3.01638255 |
| 32 | Lymphoma (HP:0002665) | 3.00204795 |
| 33 | Recurrent cutaneous fungal infections (HP:0011370) | 2.99576680 |
| 34 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.99576680 |
| 35 | Increased IgE level (HP:0003212) | 2.95813199 |
| 36 | Obstructive lung disease (HP:0006536) | 2.94445303 |
| 37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.94445303 |
| 38 | IgM deficiency (HP:0002850) | 2.94100048 |
| 39 | Cellular immunodeficiency (HP:0005374) | 2.93187592 |
| 40 | Lymphopenia (HP:0001888) | 2.85448279 |
| 41 | Agammaglobulinemia (HP:0004432) | 2.82835296 |
| 42 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.81438246 |
| 43 | Tetany (HP:0001281) | 2.80795826 |
| 44 | Inflammation of the large intestine (HP:0002037) | 2.79979534 |
| 45 | Cerebral palsy (HP:0100021) | 2.78439864 |
| 46 | Microcytic anemia (HP:0001935) | 2.77573401 |
| 47 | Leukocytosis (HP:0001974) | 2.76537354 |
| 48 | Recurrent skin infections (HP:0001581) | 2.68697905 |
| 49 | Broad face (HP:0000283) | 2.68232849 |
| 50 | Eosinophilia (HP:0001880) | 2.67750175 |
| 51 | Hypoplasia of the thymus (HP:0000778) | 2.65917119 |
| 52 | B lymphocytopenia (HP:0010976) | 2.63731831 |
| 53 | Abnormality of B cell number (HP:0010975) | 2.62386174 |
| 54 | Gastrointestinal inflammation (HP:0004386) | 2.62290836 |
| 55 | Retrobulbar optic neuritis (HP:0100654) | 2.61793106 |
| 56 | Optic neuritis (HP:0100653) | 2.61793106 |
| 57 | Birth length less than 3rd percentile (HP:0003561) | 2.60278330 |
| 58 | Petechiae (HP:0000967) | 2.59706739 |
| 59 | Abnormality of T cell physiology (HP:0011840) | 2.59583661 |
| 60 | Hypochromic microcytic anemia (HP:0004840) | 2.58729387 |
| 61 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.57837851 |
| 62 | Granulocytopenia (HP:0001913) | 2.51261410 |
| 63 | Long clavicles (HP:0000890) | 2.47012591 |
| 64 | Mediastinal lymphadenopathy (HP:0100721) | 2.45132966 |
| 65 | Oral leukoplakia (HP:0002745) | 2.43913668 |
| 66 | Orchitis (HP:0100796) | 2.40639023 |
| 67 | Conjunctival telangiectasia (HP:0000524) | 2.34354844 |
| 68 | Symptomatic seizures (HP:0011145) | 2.32115153 |
| 69 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.31708782 |
| 70 | Epistaxis (HP:0000421) | 2.25426619 |
| 71 | Spinal canal stenosis (HP:0003416) | 2.25175186 |
| 72 | Pulmonary embolism (HP:0002204) | 2.24514387 |
| 73 | Hemoptysis (HP:0002105) | 2.23215631 |
| 74 | Alveolar cell carcinoma (HP:0006519) | 2.14864613 |
| 75 | Autoimmune thrombocytopenia (HP:0001973) | 2.12794971 |
| 76 | Colitis (HP:0002583) | 2.12559452 |
| 77 | Vasculitis (HP:0002633) | 2.10952999 |
| 78 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.09901874 |
| 79 | Keratoconjunctivitis sicca (HP:0001097) | 2.08157455 |
| 80 | Hypochromic anemia (HP:0001931) | 2.06989929 |
| 81 | Hypoparathyroidism (HP:0000829) | 2.04395338 |
| 82 | 3-Methylglutaconic aciduria (HP:0003535) | 2.01580019 |
| 83 | Gastrointestinal infarctions (HP:0005244) | 1.96967972 |
| 84 | Keratoconjunctivitis (HP:0001096) | 1.95973760 |
| 85 | Pulmonary infiltrates (HP:0002113) | 1.94734386 |
| 86 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.94034938 |
| 87 | Hemiplegia (HP:0002301) | 1.91589805 |
| 88 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.89464633 |
| 89 | Bronchitis (HP:0012387) | 1.86797468 |
| 90 | Hypomagnesemia (HP:0002917) | 1.84762221 |
| 91 | Purpura (HP:0000979) | 1.84091006 |
| 92 | Nasal polyposis (HP:0100582) | 1.83155556 |
| 93 | Prolonged bleeding time (HP:0003010) | 1.82208259 |
| 94 | Papilledema (HP:0001085) | 1.78860091 |
| 95 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.78414085 |
| 96 | Seborrheic dermatitis (HP:0001051) | 1.78043777 |
| 97 | Urticaria (HP:0001025) | 1.77961952 |
| 98 | Sepsis (HP:0100806) | 1.72881165 |
| 99 | Gingivitis (HP:0000230) | 1.71750034 |
| 100 | Amyotrophic lateral sclerosis (HP:0007354) | 1.71294027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 5.19030461 |
| 2 | TXK | 4.23340614 |
| 3 | TESK2 | 3.87308818 |
| 4 | MAP4K1 | 3.50357887 |
| 5 | GRK7 | 3.46666162 |
| 6 | FES | 2.61975440 |
| 7 | ITK | 2.53517453 |
| 8 | MAP3K12 | 2.48372995 |
| 9 | RIPK4 | 2.41931430 |
| 10 | TAF1 | 2.40020540 |
| 11 | BTK | 2.31366307 |
| 12 | TGFBR2 | 2.25448427 |
| 13 | STK10 | 2.24802759 |
| 14 | GRK6 | 2.13158337 |
| 15 | TAOK3 | 2.08760893 |
| 16 | MOS | 2.02230570 |
| 17 | TESK1 | 1.98736515 |
| 18 | CSK | 1.90941947 |
| 19 | TBK1 | 1.67665472 |
| 20 | HCK | 1.60774339 |
| 21 | JAK3 | 1.59915836 |
| 22 | LCK | 1.59488258 |
| 23 | CLK1 | 1.57283525 |
| 24 | ZAP70 | 1.56331301 |
| 25 | PASK | 1.46985252 |
| 26 | SYK | 1.42263055 |
| 27 | TEC | 1.37294853 |
| 28 | MST4 | 1.32298010 |
| 29 | TNK2 | 1.28373342 |
| 30 | TYK2 | 1.25060400 |
| 31 | GRK5 | 1.24184944 |
| 32 | PRKCH | 1.23842902 |
| 33 | JAK2 | 1.23445665 |
| 34 | LYN | 1.22317333 |
| 35 | IKBKE | 1.20871592 |
| 36 | EPHB1 | 1.16849925 |
| 37 | MAP3K11 | 1.11252269 |
| 38 | SIK3 | 1.10168028 |
| 39 | MYLK | 1.01255410 |
| 40 | IRAK4 | 0.99907023 |
| 41 | CAMKK2 | 0.98331669 |
| 42 | CSF1R | 0.97535844 |
| 43 | BMPR2 | 0.95130688 |
| 44 | NLK | 0.93663457 |
| 45 | ERN1 | 0.93519455 |
| 46 | PRKCQ | 0.91166089 |
| 47 | MARK3 | 0.89080095 |
| 48 | PDK1 | 0.88868699 |
| 49 | EIF2AK3 | 0.88654407 |
| 50 | FGR | 0.85759439 |
| 51 | DAPK1 | 0.78409127 |
| 52 | CDK4 | 0.77192639 |
| 53 | SCYL2 | 0.77144915 |
| 54 | PTK6 | 0.77113430 |
| 55 | NTRK2 | 0.76795261 |
| 56 | BLK | 0.74387221 |
| 57 | JAK1 | 0.73041761 |
| 58 | NEK6 | 0.72947527 |
| 59 | STK39 | 0.71151944 |
| 60 | MAPK11 | 0.70768447 |
| 61 | MAP2K3 | 0.70606958 |
| 62 | BCKDK | 0.69720223 |
| 63 | MAP3K3 | 0.69290815 |
| 64 | ILK | 0.64324907 |
| 65 | WNK4 | 0.61701497 |
| 66 | FYN | 0.60867426 |
| 67 | LIMK1 | 0.60412115 |
| 68 | RPS6KA4 | 0.55626336 |
| 69 | PRPF4B | 0.54887120 |
| 70 | IKBKB | 0.53742045 |
| 71 | HIPK2 | 0.52823610 |
| 72 | KIT | 0.49317385 |
| 73 | TAOK1 | 0.48814868 |
| 74 | AURKA | 0.46512543 |
| 75 | TAOK2 | 0.46191775 |
| 76 | PAK1 | 0.44959831 |
| 77 | MAPKAPK2 | 0.44540733 |
| 78 | SIK2 | 0.44217471 |
| 79 | CAMKK1 | 0.43769750 |
| 80 | PIM1 | 0.43450618 |
| 81 | MAP2K6 | 0.38742382 |
| 82 | MAPK13 | 0.38107723 |
| 83 | TRPM7 | 0.37362585 |
| 84 | MAP2K2 | 0.36442179 |
| 85 | MAP3K5 | 0.35192500 |
| 86 | FGFR4 | 0.31597176 |
| 87 | IGF1R | 0.30546064 |
| 88 | INSR | 0.29558926 |
| 89 | MAP3K7 | 0.27862672 |
| 90 | MAP3K14 | 0.27554297 |
| 91 | PAK4 | 0.26437869 |
| 92 | STK38 | 0.24568598 |
| 93 | TYRO3 | 0.21449027 |
| 94 | RPS6KA5 | 0.21147974 |
| 95 | ADRBK1 | 0.20885282 |
| 96 | PRKD2 | 0.20723353 |
| 97 | ADRBK2 | 0.19930549 |
| 98 | MAPKAPK3 | 0.19894297 |
| 99 | MAP3K1 | 0.19784583 |
| 100 | PIK3CG | 0.19471272 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 7.56683727 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.43005897 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.28763391 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.22770853 |
| 5 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 3.00150728 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.86755229 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 2.76128105 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.69387729 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.63112954 |
| 10 | Measles_Homo sapiens_hsa05162 | 2.36780482 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.92891594 |
| 12 | Shigellosis_Homo sapiens_hsa05131 | 1.85959790 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.77281319 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.58105147 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.56228884 |
| 16 | Viral myocarditis_Homo sapiens_hsa05416 | 1.55098191 |
| 17 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.54950469 |
| 18 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.54418669 |
| 19 | Salmonella infection_Homo sapiens_hsa05132 | 1.53874789 |
| 20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52524608 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.52216429 |
| 22 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.51247549 |
| 23 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.49990754 |
| 24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.46614667 |
| 25 | Malaria_Homo sapiens_hsa05144 | 1.45372383 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.38651077 |
| 27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.33888712 |
| 28 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.21016413 |
| 29 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.16891257 |
| 30 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.16267695 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.15801793 |
| 32 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.15036442 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.12818699 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.12403374 |
| 35 | Parkinsons disease_Homo sapiens_hsa05012 | 1.10671871 |
| 36 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.09514674 |
| 37 | Platelet activation_Homo sapiens_hsa04611 | 1.04340997 |
| 38 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.02516719 |
| 39 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.99225823 |
| 40 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.97516721 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.93792117 |
| 42 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.92844335 |
| 43 | Tuberculosis_Homo sapiens_hsa05152 | 0.91471147 |
| 44 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.85937919 |
| 45 | Influenza A_Homo sapiens_hsa05164 | 0.83161574 |
| 46 | Pertussis_Homo sapiens_hsa05133 | 0.81076654 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 0.77050192 |
| 48 | Alzheimers disease_Homo sapiens_hsa05010 | 0.75842960 |
| 49 | Asthma_Homo sapiens_hsa05310 | 0.75762816 |
| 50 | Endocytosis_Homo sapiens_hsa04144 | 0.75051445 |
| 51 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.74379129 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.74202155 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.70918649 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.70670608 |
| 55 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.70190545 |
| 56 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.69743850 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.69061455 |
| 58 | HTLV-I infection_Homo sapiens_hsa05166 | 0.68876065 |
| 59 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.60419087 |
| 60 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.59964758 |
| 61 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.59636418 |
| 62 | Hepatitis B_Homo sapiens_hsa05161 | 0.59587098 |
| 63 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.58281997 |
| 64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.55991589 |
| 65 | Ribosome_Homo sapiens_hsa03010 | 0.55982238 |
| 66 | Huntingtons disease_Homo sapiens_hsa05016 | 0.50911988 |
| 67 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.49233450 |
| 68 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.48447192 |
| 69 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.43523968 |
| 70 | Hepatitis C_Homo sapiens_hsa05160 | 0.40438499 |
| 71 | Renin secretion_Homo sapiens_hsa04924 | 0.39196585 |
| 72 | DNA replication_Homo sapiens_hsa03030 | 0.38429846 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.37796900 |
| 74 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.34477082 |
| 75 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.32586097 |
| 76 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.29890499 |
| 77 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.28851140 |
| 78 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.25648664 |
| 79 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.24907426 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24621844 |
| 81 | Peroxisome_Homo sapiens_hsa04146 | 0.24042020 |
| 82 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.22227337 |
| 83 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.22194729 |
| 84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.21411067 |
| 85 | Base excision repair_Homo sapiens_hsa03410 | 0.19228611 |
| 86 | Long-term potentiation_Homo sapiens_hsa04720 | 0.18014528 |
| 87 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.17689455 |
| 88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.16016598 |
| 89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.15568338 |
| 90 | Phagosome_Homo sapiens_hsa04145 | 0.15469151 |
| 91 | Colorectal cancer_Homo sapiens_hsa05210 | 0.14495473 |
| 92 | Mismatch repair_Homo sapiens_hsa03430 | 0.13015953 |
| 93 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.10255177 |
| 94 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.10206234 |
| 95 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.09138536 |
| 96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.08101812 |
| 97 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.07559048 |
| 98 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.07054587 |
| 99 | ABC transporters_Homo sapiens_hsa02010 | 0.06038863 |
| 100 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.05463676 |

