

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.07397360 |
| 2 | negative T cell selection (GO:0043383) | 7.05370976 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 7.00557843 |
| 4 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.62224113 |
| 5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.43803947 |
| 6 | negative regulation of cell killing (GO:0031342) | 6.43803947 |
| 7 | positive T cell selection (GO:0043368) | 6.26269588 |
| 8 | cellular response to interleukin-15 (GO:0071350) | 5.87076574 |
| 9 | cytidine deamination (GO:0009972) | 5.84943436 |
| 10 | cytidine metabolic process (GO:0046087) | 5.84943436 |
| 11 | cytidine catabolic process (GO:0006216) | 5.84943436 |
| 12 | negative thymic T cell selection (GO:0045060) | 5.73690247 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.62261085 |
| 14 | response to interleukin-15 (GO:0070672) | 5.58546179 |
| 15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.53113442 |
| 16 | regulation of regulatory T cell differentiation (GO:0045589) | 5.40264458 |
| 17 | tolerance induction (GO:0002507) | 5.36811975 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.27129594 |
| 19 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 5.20507737 |
| 20 | DNA deamination (GO:0045006) | 5.17464582 |
| 21 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.11835142 |
| 22 | activated T cell proliferation (GO:0050798) | 5.05900612 |
| 23 | negative regulation of T cell mediated immunity (GO:0002710) | 5.04318268 |
| 24 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.01290630 |
| 25 | positive thymic T cell selection (GO:0045059) | 4.97864192 |
| 26 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.96874027 |
| 27 | T cell selection (GO:0045058) | 4.94542200 |
| 28 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.86421715 |
| 29 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.85299897 |
| 30 | T cell migration (GO:0072678) | 4.85242953 |
| 31 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.72595023 |
| 32 | thymic T cell selection (GO:0045061) | 4.69483346 |
| 33 | cellular response to interferon-beta (GO:0035458) | 4.61199182 |
| 34 | positive regulation of defense response to virus by host (GO:0002230) | 4.59971946 |
| 35 | negative regulation of stress fiber assembly (GO:0051497) | 4.57101466 |
| 36 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.50242566 |
| 37 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.40936818 |
| 38 | regulation of T cell tolerance induction (GO:0002664) | 4.37906729 |
| 39 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.35798543 |
| 40 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.35798543 |
| 41 | positive regulation of cell killing (GO:0031343) | 4.26390037 |
| 42 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.25991381 |
| 43 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.20392670 |
| 44 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.19078496 |
| 45 | regulation of gamma-delta T cell activation (GO:0046643) | 4.18402752 |
| 46 | T cell receptor signaling pathway (GO:0050852) | 4.15042022 |
| 47 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.13636077 |
| 48 | positive regulation of B cell differentiation (GO:0045579) | 4.12588518 |
| 49 | cellular defense response (GO:0006968) | 4.10577775 |
| 50 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.05824735 |
| 51 | negative regulation of interleukin-12 production (GO:0032695) | 4.00926046 |
| 52 | regulation of B cell differentiation (GO:0045577) | 3.98878778 |
| 53 | interferon-gamma production (GO:0032609) | 3.98491291 |
| 54 | regulation of cell killing (GO:0031341) | 3.97016548 |
| 55 | positive regulation of tolerance induction (GO:0002645) | 3.90727136 |
| 56 | response to interferon-beta (GO:0035456) | 3.89639222 |
| 57 | positive regulation of granulocyte differentiation (GO:0030854) | 3.85692063 |
| 58 | leukocyte aggregation (GO:0070486) | 3.85308236 |
| 59 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.83895720 |
| 60 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.82369914 |
| 61 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.77995919 |
| 62 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.74808388 |
| 63 | regulation of defense response to virus by host (GO:0050691) | 3.71730346 |
| 64 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.66901758 |
| 65 | positive regulation of T cell mediated immunity (GO:0002711) | 3.62410238 |
| 66 | regulation of tolerance induction (GO:0002643) | 3.62155290 |
| 67 | cytolysis (GO:0019835) | 3.51796000 |
| 68 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.49949128 |
| 69 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.48054041 |
| 70 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.43903931 |
| 71 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.41987350 |
| 72 | positive regulation of interleukin-4 production (GO:0032753) | 3.41424701 |
| 73 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.39897515 |
| 74 | lymphocyte migration (GO:0072676) | 3.39228744 |
| 75 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.38790149 |
| 76 | positive regulation of isotype switching (GO:0045830) | 3.36950833 |
| 77 | negative regulation of T cell apoptotic process (GO:0070233) | 3.32923785 |
| 78 | positive regulation of humoral immune response (GO:0002922) | 3.31500004 |
| 79 | alpha-beta T cell differentiation (GO:0046632) | 3.30970070 |
| 80 | regulation of T cell mediated immunity (GO:0002709) | 3.26741723 |
| 81 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.18177059 |
| 82 | lymphocyte chemotaxis (GO:0048247) | 3.16827562 |
| 83 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.13409412 |
| 84 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.13091966 |
| 85 | positive regulation of B cell mediated immunity (GO:0002714) | 3.13091966 |
| 86 | T cell costimulation (GO:0031295) | 3.12089691 |
| 87 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.10284531 |
| 88 | positive regulation of DNA recombination (GO:0045911) | 3.10245108 |
| 89 | lymphocyte costimulation (GO:0031294) | 3.08289055 |
| 90 | NIK/NF-kappaB signaling (GO:0038061) | 3.07275464 |
| 91 | mast cell activation (GO:0045576) | 3.06956351 |
| 92 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.04947091 |
| 93 | pentose metabolic process (GO:0019321) | 3.03906165 |
| 94 | regulation of chronic inflammatory response (GO:0002676) | 3.03391824 |
| 95 | regulation of isotype switching (GO:0045191) | 3.00919406 |
| 96 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2.99946858 |
| 97 | regulation of lymphocyte mediated immunity (GO:0002706) | 2.97366784 |
| 98 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.96875689 |
| 99 | negative regulation of viral genome replication (GO:0045071) | 2.95843685 |
| 100 | T cell differentiation (GO:0030217) | 2.92997139 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.33681153 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.77293002 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.47241126 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.46340353 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.89374101 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.84780819 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.73137814 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.64017969 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.54947309 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.40678015 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.15509929 |
| 12 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.12061440 |
| 13 | MAF_26560356_Chip-Seq_TH1_Human | 2.67690742 |
| 14 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.62851423 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.54034467 |
| 16 | MYB_26560356_Chip-Seq_TH1_Human | 2.50069749 |
| 17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.46994903 |
| 18 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.40100844 |
| 19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.39845147 |
| 20 | UTX_26944678_Chip-Seq_JUKART_Human | 2.24245699 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.22173997 |
| 22 | MAF_26560356_Chip-Seq_TH2_Human | 2.14857837 |
| 23 | GATA3_26560356_Chip-Seq_TH2_Human | 2.11185173 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.06409273 |
| 25 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.00640626 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.99046386 |
| 27 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.97119653 |
| 28 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.96905068 |
| 29 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.87387281 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.83083269 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.77041295 |
| 32 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.74476085 |
| 33 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.58501071 |
| 34 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.56586316 |
| 35 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.55655249 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55386463 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.53704168 |
| 38 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51037917 |
| 39 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.41570833 |
| 40 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.35867052 |
| 41 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.34462744 |
| 42 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.34362005 |
| 43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.32707872 |
| 44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.30482981 |
| 45 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24117754 |
| 46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.22866193 |
| 47 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.19880568 |
| 48 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17405132 |
| 49 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.17153700 |
| 50 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.15777044 |
| 51 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.11986944 |
| 52 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09699312 |
| 53 | VDR_22108803_ChIP-Seq_LS180_Human | 1.08966685 |
| 54 | SPI1_23127762_ChIP-Seq_K562_Human | 1.07940525 |
| 55 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.04612694 |
| 56 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.04567897 |
| 57 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04539310 |
| 58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.01872908 |
| 59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98521651 |
| 60 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.97977492 |
| 61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97782172 |
| 62 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.96884455 |
| 63 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95391792 |
| 64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.95323350 |
| 65 | MYC_22102868_ChIP-Seq_BL_Human | 0.94601328 |
| 66 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.94289219 |
| 67 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.93157440 |
| 68 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92886386 |
| 69 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92434213 |
| 70 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92015726 |
| 71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90438328 |
| 72 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.89673084 |
| 73 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.88837780 |
| 74 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.87870342 |
| 75 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.87850677 |
| 76 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.86650169 |
| 77 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.85277763 |
| 78 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.85009385 |
| 79 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84946358 |
| 80 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.84944717 |
| 81 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.84814109 |
| 82 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.84769009 |
| 83 | GATA3_26560356_Chip-Seq_TH1_Human | 0.83435002 |
| 84 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.81648759 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.80631393 |
| 86 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.79839281 |
| 87 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.78658792 |
| 88 | P300_27268052_Chip-Seq_Bcells_Human | 0.78254612 |
| 89 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.77413746 |
| 90 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.76301256 |
| 91 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.75685757 |
| 92 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.74347745 |
| 93 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73962744 |
| 94 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.73854361 |
| 95 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.71306083 |
| 96 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.70764436 |
| 97 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.70508270 |
| 98 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.69351143 |
| 99 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.69074351 |
| 100 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68113032 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.02626667 |
| 2 | MP0003763_abnormal_thymus_physiology | 4.64369173 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.13167890 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 3.89293716 |
| 5 | MP0001800_abnormal_humoral_immune | 3.04314854 |
| 6 | MP0000685_abnormal_immune_system | 2.96736396 |
| 7 | MP0003436_decreased_susceptibility_to | 2.92088757 |
| 8 | MP0005387_immune_system_phenotype | 2.90370338 |
| 9 | MP0001790_abnormal_immune_system | 2.90370338 |
| 10 | MP0001853_heart_inflammation | 2.89768628 |
| 11 | MP0009785_altered_susceptibility_to | 2.77702252 |
| 12 | MP0005025_abnormal_response_to | 2.74880202 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.70168976 |
| 14 | MP0003866_abnormal_defecation | 2.65598698 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.65295052 |
| 16 | MP0002723_abnormal_immune_serum | 2.61395127 |
| 17 | MP0001819_abnormal_immune_cell | 2.60096510 |
| 18 | MP0002166_altered_tumor_susceptibility | 2.38391231 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.38347842 |
| 20 | MP0002405_respiratory_system_inflammati | 2.36804540 |
| 21 | MP0000703_abnormal_thymus_morphology | 2.31182446 |
| 22 | MP0001873_stomach_inflammation | 2.28508586 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 2.26472818 |
| 24 | MP0002419_abnormal_innate_immunity | 2.18957668 |
| 25 | MP0003300_gastrointestinal_ulcer | 2.17800306 |
| 26 | MP0006082_CNS_inflammation | 2.17603767 |
| 27 | MP0003724_increased_susceptibility_to | 2.12681755 |
| 28 | MP0010155_abnormal_intestine_physiology | 2.10457665 |
| 29 | MP0002398_abnormal_bone_marrow | 2.08222418 |
| 30 | MP0000716_abnormal_immune_system | 2.07058100 |
| 31 | MP0003045_fibrosis | 1.96346125 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.88344408 |
| 33 | MP0003878_abnormal_ear_physiology | 1.88344408 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.87007507 |
| 35 | MP0002722_abnormal_immune_system | 1.73809732 |
| 36 | MP0002138_abnormal_hepatobiliary_system | 1.73108386 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.66496291 |
| 38 | MP0002006_tumorigenesis | 1.61848472 |
| 39 | MP0002429_abnormal_blood_cell | 1.58405846 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.49120986 |
| 41 | MP0003448_altered_tumor_morphology | 1.47189267 |
| 42 | MP0004947_skin_inflammation | 1.44316175 |
| 43 | MP0005310_abnormal_salivary_gland | 1.44258082 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.42312135 |
| 45 | MP0004381_abnormal_hair_follicle | 1.40118228 |
| 46 | MP0008469_abnormal_protein_level | 1.32662665 |
| 47 | MP0005464_abnormal_platelet_physiology | 1.27275697 |
| 48 | MP0004130_abnormal_muscle_cell | 1.24779001 |
| 49 | MP0009278_abnormal_bone_marrow | 1.20569611 |
| 50 | MP0000465_gastrointestinal_hemorrhage | 1.16847049 |
| 51 | MP0005075_abnormal_melanosome_morpholog | 1.14132597 |
| 52 | MP0001533_abnormal_skeleton_physiology | 1.12171934 |
| 53 | MP0002163_abnormal_gland_morphology | 1.09604680 |
| 54 | MP0009764_decreased_sensitivity_to | 1.09484486 |
| 55 | MP0000604_amyloidosis | 1.06026050 |
| 56 | MP0009763_increased_sensitivity_to | 1.02854914 |
| 57 | MP0003303_peritoneal_inflammation | 1.02034395 |
| 58 | MP0009840_abnormal_foam_cell | 1.01100131 |
| 59 | MP0001348_abnormal_lacrimal_gland | 0.99499393 |
| 60 | MP0005379_endocrine/exocrine_gland_phen | 0.95488320 |
| 61 | MP0000858_altered_metastatic_potential | 0.94755033 |
| 62 | MP0001501_abnormal_sleep_pattern | 0.90404559 |
| 63 | MP0001765_abnormal_ion_homeostasis | 0.88214474 |
| 64 | MP0002998_abnormal_bone_remodeling | 0.85768271 |
| 65 | MP0005167_abnormal_blood-brain_barrier | 0.80432930 |
| 66 | MP0001764_abnormal_homeostasis | 0.78041769 |
| 67 | MP0004036_abnormal_muscle_relaxation | 0.76007010 |
| 68 | MP0003191_abnormal_cellular_cholesterol | 0.75142258 |
| 69 | MP0008057_abnormal_DNA_replication | 0.74364656 |
| 70 | MP0001919_abnormal_reproductive_system | 0.73952532 |
| 71 | MP0003959_abnormal_lean_body | 0.72221130 |
| 72 | MP0002736_abnormal_nociception_after | 0.72068097 |
| 73 | MP0001986_abnormal_taste_sensitivity | 0.70815357 |
| 74 | MP0002693_abnormal_pancreas_physiology | 0.69422525 |
| 75 | MP0002933_joint_inflammation | 0.69378901 |
| 76 | MP0002168_other_aberrant_phenotype | 0.67735988 |
| 77 | MP0004142_abnormal_muscle_tone | 0.65727962 |
| 78 | MP0001663_abnormal_digestive_system | 0.65073991 |
| 79 | MP0005410_abnormal_fertilization | 0.63701651 |
| 80 | MP0001851_eye_inflammation | 0.61413828 |
| 81 | MP0001968_abnormal_touch/_nociception | 0.61113615 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.60727049 |
| 83 | MP0004084_abnormal_cardiac_muscle | 0.59668405 |
| 84 | MP0005166_decreased_susceptibility_to | 0.59241359 |
| 85 | MP0008260_abnormal_autophagy | 0.56989412 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.56527104 |
| 87 | MP0005448_abnormal_energy_balance | 0.56174111 |
| 88 | MP0002254_reproductive_system_inflammat | 0.55942324 |
| 89 | MP0008872_abnormal_physiological_respon | 0.55405705 |
| 90 | MP0003646_muscle_fatigue | 0.51426944 |
| 91 | MP0005165_increased_susceptibility_to | 0.50750531 |
| 92 | MP0006035_abnormal_mitochondrial_morpho | 0.49345708 |
| 93 | MP0000490_abnormal_crypts_of | 0.48184741 |
| 94 | MP0003075_altered_response_to | 0.47336163 |
| 95 | MP0003795_abnormal_bone_structure | 0.46873364 |
| 96 | MP0004782_abnormal_surfactant_physiolog | 0.45239190 |
| 97 | MP0005645_abnormal_hypothalamus_physiol | 0.45152001 |
| 98 | MP0005083_abnormal_biliary_tract | 0.44961455 |
| 99 | MP0005390_skeleton_phenotype | 0.43095846 |
| 100 | MP0009643_abnormal_urine_homeostasis | 0.42269909 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 8.35601920 |
| 2 | Stomatitis (HP:0010280) | 6.27593565 |
| 3 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 5.63231063 |
| 4 | T lymphocytopenia (HP:0005403) | 5.47903021 |
| 5 | Recurrent cutaneous fungal infections (HP:0011370) | 5.34510238 |
| 6 | Chronic mucocutaneous candidiasis (HP:0002728) | 5.34510238 |
| 7 | Eczematoid dermatitis (HP:0000976) | 5.13977420 |
| 8 | Abnormality of T cells (HP:0002843) | 5.13128012 |
| 9 | Abnormality of T cell number (HP:0011839) | 5.07454404 |
| 10 | Panhypogammaglobulinemia (HP:0003139) | 5.03167184 |
| 11 | IgG deficiency (HP:0004315) | 4.82127950 |
| 12 | Recurrent fungal infections (HP:0002841) | 4.76610549 |
| 13 | Severe combined immunodeficiency (HP:0004430) | 4.71013593 |
| 14 | Encephalitis (HP:0002383) | 4.34803359 |
| 15 | Autoimmune hemolytic anemia (HP:0001890) | 4.30726133 |
| 16 | Agammaglobulinemia (HP:0004432) | 4.20178291 |
| 17 | Colitis (HP:0002583) | 3.98104605 |
| 18 | Myositis (HP:0100614) | 3.86248431 |
| 19 | Chronic diarrhea (HP:0002028) | 3.76311378 |
| 20 | Increased IgE level (HP:0003212) | 3.74517463 |
| 21 | Recurrent bronchitis (HP:0002837) | 3.73381588 |
| 22 | Increased IgM level (HP:0003496) | 3.71601067 |
| 23 | Abnormality of eosinophils (HP:0001879) | 3.66675300 |
| 24 | Combined immunodeficiency (HP:0005387) | 3.65381296 |
| 25 | Abnormality of T cell physiology (HP:0011840) | 3.58668280 |
| 26 | Pustule (HP:0200039) | 3.58187366 |
| 27 | Inflammation of the large intestine (HP:0002037) | 3.53218467 |
| 28 | Pigmentary retinal degeneration (HP:0001146) | 3.52719168 |
| 29 | Lymphopenia (HP:0001888) | 3.43222789 |
| 30 | Recurrent skin infections (HP:0001581) | 3.37333313 |
| 31 | Meningitis (HP:0001287) | 3.36668591 |
| 32 | Leukocytosis (HP:0001974) | 3.36408125 |
| 33 | Gastrointestinal inflammation (HP:0004386) | 3.29304128 |
| 34 | Thyroiditis (HP:0100646) | 3.25535100 |
| 35 | Abnormality of small intestinal villus morphology (HP:0011472) | 3.19403643 |
| 36 | Villous atrophy (HP:0011473) | 3.19403643 |
| 37 | Vasculitis (HP:0002633) | 3.17090415 |
| 38 | Hypoplasia of the thymus (HP:0000778) | 3.16720053 |
| 39 | Retrobulbar optic neuritis (HP:0100654) | 3.16395380 |
| 40 | Optic neuritis (HP:0100653) | 3.16395380 |
| 41 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.13634154 |
| 42 | Eosinophilia (HP:0001880) | 3.03459782 |
| 43 | Recurrent viral infections (HP:0004429) | 2.98764723 |
| 44 | Orchitis (HP:0100796) | 2.98502667 |
| 45 | Viral hepatitis (HP:0006562) | 2.93291123 |
| 46 | Recurrent abscess formation (HP:0002722) | 2.91172946 |
| 47 | Petechiae (HP:0000967) | 2.80423796 |
| 48 | Abnormality of macrophages (HP:0004311) | 2.79059596 |
| 49 | Recurrent bacterial skin infections (HP:0005406) | 2.76411175 |
| 50 | Granulocytopenia (HP:0001913) | 2.74415105 |
| 51 | Hypergammaglobulinemia (HP:0010702) | 2.72894857 |
| 52 | Aplastic anemia (HP:0001915) | 2.72202671 |
| 53 | Keratoconjunctivitis sicca (HP:0001097) | 2.71620443 |
| 54 | Severe visual impairment (HP:0001141) | 2.66936488 |
| 55 | Pulmonary infiltrates (HP:0002113) | 2.65639857 |
| 56 | IgM deficiency (HP:0002850) | 2.58633373 |
| 57 | Lymphoma (HP:0002665) | 2.55431667 |
| 58 | Acute hepatic failure (HP:0006554) | 2.54721021 |
| 59 | Keratoconjunctivitis (HP:0001096) | 2.49777380 |
| 60 | Alveolar cell carcinoma (HP:0006519) | 2.48092385 |
| 61 | Gastrointestinal infarctions (HP:0005244) | 2.46841926 |
| 62 | Mediastinal lymphadenopathy (HP:0100721) | 2.46812605 |
| 63 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.22467895 |
| 64 | Hepatosplenomegaly (HP:0001433) | 2.18717046 |
| 65 | Abnormality of the pleura (HP:0002103) | 2.17310938 |
| 66 | Spontaneous hematomas (HP:0007420) | 2.16518841 |
| 67 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.15360596 |
| 68 | Cellular immunodeficiency (HP:0005374) | 2.13868769 |
| 69 | Neutropenia (HP:0001875) | 2.12677593 |
| 70 | Glomerulopathy (HP:0100820) | 2.06907025 |
| 71 | Hyperlipoproteinemia (HP:0010980) | 2.05135923 |
| 72 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.04729817 |
| 73 | Chest pain (HP:0100749) | 2.04431208 |
| 74 | Micronodular cirrhosis (HP:0001413) | 2.03041247 |
| 75 | Skin rash (HP:0000988) | 2.01914139 |
| 76 | Autoimmune thrombocytopenia (HP:0001973) | 2.01456347 |
| 77 | Purpura (HP:0000979) | 2.01321622 |
| 78 | Pancytopenia (HP:0001876) | 2.00332429 |
| 79 | Interstitial pulmonary disease (HP:0006530) | 2.00191700 |
| 80 | Obstructive lung disease (HP:0006536) | 1.98621905 |
| 81 | Chronic obstructive pulmonary disease (HP:0006510) | 1.98621905 |
| 82 | Bronchitis (HP:0012387) | 1.96648994 |
| 83 | Thyroid-stimulating hormone excess (HP:0002925) | 1.96482882 |
| 84 | Microcytic anemia (HP:0001935) | 1.95579260 |
| 85 | Hemoptysis (HP:0002105) | 1.94920625 |
| 86 | Hepatitis (HP:0012115) | 1.93194827 |
| 87 | Hypoplasia of the pons (HP:0012110) | 1.87425672 |
| 88 | Carpal bone hypoplasia (HP:0001498) | 1.83712137 |
| 89 | Stomach cancer (HP:0012126) | 1.80029463 |
| 90 | Abnormality of the pons (HP:0007361) | 1.79984004 |
| 91 | Hypoproteinemia (HP:0003075) | 1.79138185 |
| 92 | Tetraplegia (HP:0002445) | 1.76871259 |
| 93 | Joint swelling (HP:0001386) | 1.76524316 |
| 94 | Gangrene (HP:0100758) | 1.76452321 |
| 95 | Thoracic kyphosis (HP:0002942) | 1.76380091 |
| 96 | Pulmonary embolism (HP:0002204) | 1.75833645 |
| 97 | Abnormality of B cell number (HP:0010975) | 1.74010960 |
| 98 | B lymphocytopenia (HP:0010976) | 1.72778953 |
| 99 | Slow saccadic eye movements (HP:0000514) | 1.72579668 |
| 100 | Prolonged neonatal jaundice (HP:0006579) | 1.70985518 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.61879916 |
| 2 | MAP4K1 | 4.88079569 |
| 3 | EPHA3 | 3.83851666 |
| 4 | IRAK4 | 3.22987714 |
| 5 | EPHB1 | 3.18790312 |
| 6 | TESK2 | 2.99651722 |
| 7 | FES | 2.91838886 |
| 8 | FGFR4 | 2.61385138 |
| 9 | TNK2 | 2.59130519 |
| 10 | NLK | 2.45016984 |
| 11 | ITK | 2.30409063 |
| 12 | TAOK3 | 2.28860890 |
| 13 | MAP3K3 | 2.26350903 |
| 14 | MAP2K3 | 2.16248001 |
| 15 | CSK | 1.91086774 |
| 16 | ZAP70 | 1.88731500 |
| 17 | KDR | 1.85600578 |
| 18 | RPS6KA4 | 1.71681005 |
| 19 | TEC | 1.67077366 |
| 20 | TYK2 | 1.60991683 |
| 21 | BTK | 1.54937811 |
| 22 | ADRBK2 | 1.46204759 |
| 23 | IRAK1 | 1.42350171 |
| 24 | JAK1 | 1.37211357 |
| 25 | FGFR3 | 1.36585996 |
| 26 | IKBKE | 1.36429295 |
| 27 | LCK | 1.34586134 |
| 28 | MAP3K13 | 1.33118403 |
| 29 | HCK | 1.33078395 |
| 30 | SYK | 1.30927544 |
| 31 | GRK7 | 1.28795355 |
| 32 | RIPK4 | 1.26232435 |
| 33 | TBK1 | 1.18850413 |
| 34 | MST4 | 1.18390570 |
| 35 | GRK6 | 1.11106021 |
| 36 | IKBKB | 1.08169598 |
| 37 | MAP3K1 | 1.07791517 |
| 38 | CLK1 | 1.05380789 |
| 39 | HIPK2 | 1.01332389 |
| 40 | TESK1 | 1.00942026 |
| 41 | TAOK1 | 0.94058603 |
| 42 | LYN | 0.93771918 |
| 43 | JAK3 | 0.91674694 |
| 44 | TAOK2 | 0.91665731 |
| 45 | PASK | 0.91062974 |
| 46 | PRKCQ | 0.88780947 |
| 47 | MAPK12 | 0.87266838 |
| 48 | BLK | 0.76887882 |
| 49 | CSF1R | 0.76265232 |
| 50 | CAMKK2 | 0.75237258 |
| 51 | NUAK1 | 0.74701995 |
| 52 | MAP3K11 | 0.73330087 |
| 53 | SGK2 | 0.72893065 |
| 54 | TYRO3 | 0.68656273 |
| 55 | RPS6KA5 | 0.68593818 |
| 56 | SGK3 | 0.66488509 |
| 57 | RAF1 | 0.65223103 |
| 58 | SIK3 | 0.63889882 |
| 59 | PTK2B | 0.62108804 |
| 60 | FGR | 0.56339156 |
| 61 | JAK2 | 0.55750367 |
| 62 | SRPK1 | 0.53656930 |
| 63 | CAMKK1 | 0.48894335 |
| 64 | SGK494 | 0.48517185 |
| 65 | SGK223 | 0.48517185 |
| 66 | MAP3K14 | 0.47792406 |
| 67 | MARK3 | 0.47075734 |
| 68 | MAP2K6 | 0.43990480 |
| 69 | MAPK11 | 0.42987414 |
| 70 | NEK9 | 0.41294624 |
| 71 | MAP3K8 | 0.40788270 |
| 72 | NEK6 | 0.39021546 |
| 73 | MAP3K9 | 0.38951736 |
| 74 | FYN | 0.38751650 |
| 75 | BCKDK | 0.35395734 |
| 76 | CHUK | 0.35248595 |
| 77 | PRPF4B | 0.34040610 |
| 78 | MAPKAPK2 | 0.32132051 |
| 79 | MAP3K6 | 0.30735746 |
| 80 | PIM1 | 0.30649713 |
| 81 | STK38 | 0.28422623 |
| 82 | DYRK3 | 0.27799835 |
| 83 | STK10 | 0.27771286 |
| 84 | CDK4 | 0.24135390 |
| 85 | MAP3K12 | 0.23216142 |
| 86 | CAMK4 | 0.22619789 |
| 87 | DYRK2 | 0.22022135 |
| 88 | SIK2 | 0.21398660 |
| 89 | RET | 0.17596823 |
| 90 | PTK6 | 0.17520522 |
| 91 | RPS6KA6 | 0.15666993 |
| 92 | ALK | 0.15472517 |
| 93 | KSR2 | 0.15128860 |
| 94 | PDGFRB | 0.14573841 |
| 95 | INSR | 0.14473161 |
| 96 | KIT | 0.14394935 |
| 97 | TRPM7 | 0.12776871 |
| 98 | FER | 0.12431360 |
| 99 | PDK1 | 0.11517164 |
| 100 | IGF1R | 0.11311286 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.70510809 |
| 2 | Antigen processing and presentation_Homo sapiens_hsa04612 | 4.38444462 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.87875308 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.55040671 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.47367029 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.47168280 |
| 7 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.30495587 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.78409565 |
| 9 | Measles_Homo sapiens_hsa05162 | 2.48211710 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.39727511 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.08119929 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.97924108 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 1.96390423 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.95939100 |
| 15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.65940348 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.65762998 |
| 17 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.52991035 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.42092480 |
| 19 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.42060058 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.36069210 |
| 21 | Asthma_Homo sapiens_hsa05310 | 1.35125913 |
| 22 | Malaria_Homo sapiens_hsa05144 | 1.28188294 |
| 23 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.24131965 |
| 24 | Leishmaniasis_Homo sapiens_hsa05140 | 1.21265008 |
| 25 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.20001027 |
| 26 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.18606521 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.15075373 |
| 28 | Shigellosis_Homo sapiens_hsa05131 | 1.13763781 |
| 29 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.12292883 |
| 30 | Tuberculosis_Homo sapiens_hsa05152 | 1.11765665 |
| 31 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.09517414 |
| 32 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.08098560 |
| 33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.07763553 |
| 34 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.06837532 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.06388074 |
| 36 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.05262054 |
| 37 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.98219635 |
| 38 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.93363518 |
| 39 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.91917771 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90766458 |
| 41 | Apoptosis_Homo sapiens_hsa04210 | 0.85149773 |
| 42 | Influenza A_Homo sapiens_hsa05164 | 0.80703196 |
| 43 | Protein export_Homo sapiens_hsa03060 | 0.75460647 |
| 44 | HTLV-I infection_Homo sapiens_hsa05166 | 0.75295209 |
| 45 | Hepatitis B_Homo sapiens_hsa05161 | 0.73962468 |
| 46 | Platelet activation_Homo sapiens_hsa04611 | 0.72883628 |
| 47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.72202144 |
| 48 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.72125201 |
| 49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.71079721 |
| 50 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.66932175 |
| 51 | Pertussis_Homo sapiens_hsa05133 | 0.66653542 |
| 52 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.64777333 |
| 53 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.61671600 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60595562 |
| 55 | Phototransduction_Homo sapiens_hsa04744 | 0.59810538 |
| 56 | Salmonella infection_Homo sapiens_hsa05132 | 0.59726173 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59572714 |
| 58 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.58618765 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.57318929 |
| 60 | Hepatitis C_Homo sapiens_hsa05160 | 0.54993845 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52017800 |
| 62 | Ribosome_Homo sapiens_hsa03010 | 0.49067386 |
| 63 | Parkinsons disease_Homo sapiens_hsa05012 | 0.46794245 |
| 64 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.44356430 |
| 65 | Renin secretion_Homo sapiens_hsa04924 | 0.44247590 |
| 66 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.43461373 |
| 67 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.41981122 |
| 68 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41516001 |
| 69 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.40380465 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.39970950 |
| 71 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.39793843 |
| 72 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.39183886 |
| 73 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.38263058 |
| 74 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.38014400 |
| 75 | Basal transcription factors_Homo sapiens_hsa03022 | 0.37755441 |
| 76 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.37143731 |
| 77 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36383254 |
| 78 | Phagosome_Homo sapiens_hsa04145 | 0.36147230 |
| 79 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35930226 |
| 80 | Alzheimers disease_Homo sapiens_hsa05010 | 0.35703194 |
| 81 | Insulin resistance_Homo sapiens_hsa04931 | 0.35632619 |
| 82 | Spliceosome_Homo sapiens_hsa03040 | 0.33768452 |
| 83 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.31554367 |
| 84 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.31163364 |
| 85 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.30897511 |
| 86 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.30605735 |
| 87 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.29114736 |
| 88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.25847605 |
| 89 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.23684673 |
| 90 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.21435304 |
| 91 | RNA polymerase_Homo sapiens_hsa03020 | 0.21381536 |
| 92 | Olfactory transduction_Homo sapiens_hsa04740 | 0.20065745 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.19815034 |
| 94 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.19434129 |
| 95 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.18789132 |
| 96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.17996656 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.16273208 |
| 98 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.11826128 |
| 99 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.10950411 |
| 100 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.10469807 |

