

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 7.52157533 |
| 2 | negative thymic T cell selection (GO:0045060) | 7.15078124 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.58500213 |
| 4 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.46157246 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.31256481 |
| 6 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.84902802 |
| 7 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.74562064 |
| 8 | negative regulation of cell killing (GO:0031342) | 5.74562064 |
| 9 | thymic T cell selection (GO:0045061) | 5.70055985 |
| 10 | regulation of regulatory T cell differentiation (GO:0045589) | 5.49346908 |
| 11 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.47459995 |
| 12 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.46703699 |
| 13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.41152244 |
| 14 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.36568405 |
| 15 | T cell selection (GO:0045058) | 5.26453204 |
| 16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.26417972 |
| 17 | positive T cell selection (GO:0043368) | 5.24782883 |
| 18 | T cell migration (GO:0072678) | 5.16124125 |
| 19 | positive thymic T cell selection (GO:0045059) | 5.08223567 |
| 20 | cellular response to interleukin-15 (GO:0071350) | 5.06733235 |
| 21 | response to interleukin-15 (GO:0070672) | 5.02876522 |
| 22 | tolerance induction (GO:0002507) | 4.95622320 |
| 23 | regulation of T cell tolerance induction (GO:0002664) | 4.92770571 |
| 24 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.89763054 |
| 25 | regulation of gamma-delta T cell activation (GO:0046643) | 4.89193011 |
| 26 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.87401923 |
| 27 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.82270473 |
| 28 | positive regulation of B cell differentiation (GO:0045579) | 4.62326712 |
| 29 | regulation of interleukin-5 production (GO:0032674) | 4.58574107 |
| 30 | positive regulation of tolerance induction (GO:0002645) | 4.57600832 |
| 31 | cytidine metabolic process (GO:0046087) | 4.53680458 |
| 32 | cytidine catabolic process (GO:0006216) | 4.53680458 |
| 33 | cytidine deamination (GO:0009972) | 4.53680458 |
| 34 | actin nucleation (GO:0045010) | 4.51235451 |
| 35 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.45085093 |
| 36 | DNA deamination (GO:0045006) | 4.43452081 |
| 37 | T cell receptor signaling pathway (GO:0050852) | 4.41811094 |
| 38 | leukocyte aggregation (GO:0070486) | 4.41245100 |
| 39 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.30793083 |
| 40 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.27550671 |
| 41 | mast cell activation (GO:0045576) | 4.20187984 |
| 42 | regulation of tolerance induction (GO:0002643) | 4.11685052 |
| 43 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.08303434 |
| 44 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.04097066 |
| 45 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.04097066 |
| 46 | negative regulation of T cell mediated immunity (GO:0002710) | 4.01107683 |
| 47 | regulation of B cell differentiation (GO:0045577) | 3.98557529 |
| 48 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.93027550 |
| 49 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.92865788 |
| 50 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.91690242 |
| 51 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.87075964 |
| 52 | negative regulation of stress fiber assembly (GO:0051497) | 3.83018591 |
| 53 | positive regulation of granulocyte differentiation (GO:0030854) | 3.82401636 |
| 54 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.79299011 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.72498847 |
| 56 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.69225571 |
| 57 | positive regulation of interleukin-4 production (GO:0032753) | 3.66431476 |
| 58 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.62026955 |
| 59 | mast cell activation involved in immune response (GO:0002279) | 3.61000436 |
| 60 | mast cell degranulation (GO:0043303) | 3.61000436 |
| 61 | negative regulation of T cell apoptotic process (GO:0070233) | 3.60568342 |
| 62 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.52277030 |
| 63 | positive regulation of cell killing (GO:0031343) | 3.51274722 |
| 64 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.49312618 |
| 65 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.47898144 |
| 66 | positive regulation of interleukin-2 production (GO:0032743) | 3.43405530 |
| 67 | positive regulation of humoral immune response (GO:0002922) | 3.39940958 |
| 68 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.38102011 |
| 69 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.37410781 |
| 70 | lymphocyte migration (GO:0072676) | 3.36528831 |
| 71 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.34869546 |
| 72 | regulation of cell killing (GO:0031341) | 3.33874154 |
| 73 | regulation of defense response to virus by virus (GO:0050690) | 3.33191318 |
| 74 | type I interferon signaling pathway (GO:0060337) | 3.32771070 |
| 75 | cellular response to type I interferon (GO:0071357) | 3.32771070 |
| 76 | T cell homeostasis (GO:0043029) | 3.31633049 |
| 77 | positive regulation of T cell mediated immunity (GO:0002711) | 3.30256105 |
| 78 | response to type I interferon (GO:0034340) | 3.27954078 |
| 79 | positive regulation of isotype switching (GO:0045830) | 3.26859596 |
| 80 | T cell costimulation (GO:0031295) | 3.23699292 |
| 81 | lymphocyte costimulation (GO:0031294) | 3.19787454 |
| 82 | respiratory burst (GO:0045730) | 3.19717441 |
| 83 | activated T cell proliferation (GO:0050798) | 3.16765771 |
| 84 | regulation of interleukin-4 production (GO:0032673) | 3.15507881 |
| 85 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.15271301 |
| 86 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.14158431 |
| 87 | T cell differentiation (GO:0030217) | 3.13913493 |
| 88 | immunoglobulin mediated immune response (GO:0016064) | 3.09308381 |
| 89 | regulation of alpha-beta T cell activation (GO:0046634) | 3.08069881 |
| 90 | leukocyte degranulation (GO:0043299) | 3.07914187 |
| 91 | interferon-gamma production (GO:0032609) | 3.03682340 |
| 92 | regulation of T cell mediated immunity (GO:0002709) | 3.03500210 |
| 93 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.02192800 |
| 94 | NIK/NF-kappaB signaling (GO:0038061) | 3.01687733 |
| 95 | T cell activation (GO:0042110) | 3.01196804 |
| 96 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.00766898 |
| 97 | B cell mediated immunity (GO:0019724) | 3.00520491 |
| 98 | dendritic cell chemotaxis (GO:0002407) | 2.97414848 |
| 99 | positive regulation of DNA recombination (GO:0045911) | 2.96510835 |
| 100 | alpha-beta T cell differentiation (GO:0046632) | 2.96350456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.21838930 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.52936832 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.25670496 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.23203896 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.79478702 |
| 6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.77299215 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.76896460 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.71791321 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.69440081 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.63201859 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 3.57511685 |
| 12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.08741687 |
| 13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.02500618 |
| 14 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.94709992 |
| 15 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.84147306 |
| 16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.81859370 |
| 17 | MAF_26560356_Chip-Seq_TH1_Human | 2.76753607 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.75862753 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.62968856 |
| 20 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.60558315 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.41040688 |
| 22 | MAF_26560356_Chip-Seq_TH2_Human | 2.32716650 |
| 23 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.19210113 |
| 24 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.16652438 |
| 25 | GATA3_26560356_Chip-Seq_TH2_Human | 2.15474083 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.12945821 |
| 27 | MYC_22102868_ChIP-Seq_BL_Human | 2.04582889 |
| 28 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.97853637 |
| 29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.90978176 |
| 30 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.83741141 |
| 31 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83016864 |
| 32 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.82534956 |
| 33 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.81133587 |
| 34 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.75039509 |
| 35 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.71423808 |
| 36 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.70834210 |
| 37 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.58567515 |
| 38 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.54055406 |
| 39 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.49996021 |
| 40 | SPI1_23127762_ChIP-Seq_K562_Human | 1.43394893 |
| 41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.42355279 |
| 42 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41869820 |
| 43 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.40917137 |
| 44 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.40616552 |
| 45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.39681501 |
| 46 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.38086615 |
| 47 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.37678363 |
| 48 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.34621734 |
| 49 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.33453910 |
| 50 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.31342600 |
| 51 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27100176 |
| 52 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.26661089 |
| 53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.22221285 |
| 54 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.17041872 |
| 55 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.16407090 |
| 56 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13181872 |
| 57 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.11215721 |
| 58 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.09510512 |
| 59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09345993 |
| 60 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09321161 |
| 61 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.07383234 |
| 62 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.07110218 |
| 63 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04279541 |
| 64 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.04065865 |
| 65 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.01447604 |
| 66 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01245323 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99602678 |
| 68 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.99341208 |
| 69 | P300_27268052_Chip-Seq_Bcells_Human | 0.99242144 |
| 70 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98737845 |
| 71 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.95775487 |
| 72 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.95207034 |
| 73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.90456304 |
| 74 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.89904520 |
| 75 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.89148009 |
| 76 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.87146269 |
| 77 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.87130804 |
| 78 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.85136649 |
| 79 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.84996900 |
| 80 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.83956303 |
| 81 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.83313860 |
| 82 | GATA3_26560356_Chip-Seq_TH1_Human | 0.82271326 |
| 83 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.81875376 |
| 84 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.80879628 |
| 85 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80667643 |
| 86 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.80538430 |
| 87 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.80107997 |
| 88 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.80007424 |
| 89 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.78630535 |
| 90 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.78511027 |
| 91 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.77983164 |
| 92 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.76296035 |
| 93 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.75593399 |
| 94 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75479891 |
| 95 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.75462653 |
| 96 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.75053586 |
| 97 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.74747951 |
| 98 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73747501 |
| 99 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73187390 |
| 100 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.72851639 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.41432360 |
| 2 | MP0003763_abnormal_thymus_physiology | 4.65531326 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.80646637 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 3.20887641 |
| 5 | MP0001800_abnormal_humoral_immune | 3.14474394 |
| 6 | MP0005000_abnormal_immune_tolerance | 3.10058957 |
| 7 | MP0003436_decreased_susceptibility_to | 3.08390100 |
| 8 | MP0003724_increased_susceptibility_to | 3.04532318 |
| 9 | MP0000685_abnormal_immune_system | 3.02434862 |
| 10 | MP0005387_immune_system_phenotype | 3.02146117 |
| 11 | MP0001790_abnormal_immune_system | 3.02146117 |
| 12 | MP0009785_altered_susceptibility_to | 2.89261402 |
| 13 | MP0005025_abnormal_response_to | 2.87278425 |
| 14 | MP0002166_altered_tumor_susceptibility | 2.84546440 |
| 15 | MP0002723_abnormal_immune_serum | 2.77680475 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.73909025 |
| 17 | MP0001819_abnormal_immune_cell | 2.69021276 |
| 18 | MP0003866_abnormal_defecation | 2.63405829 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.53742768 |
| 20 | MP0001873_stomach_inflammation | 2.48222031 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.46250924 |
| 22 | MP0002398_abnormal_bone_marrow | 2.40451862 |
| 23 | MP0000703_abnormal_thymus_morphology | 2.34444081 |
| 24 | MP0002405_respiratory_system_inflammati | 2.33182226 |
| 25 | MP0000716_abnormal_immune_system | 2.27683516 |
| 26 | MP0010155_abnormal_intestine_physiology | 2.19043824 |
| 27 | MP0002419_abnormal_innate_immunity | 2.17554742 |
| 28 | MP0004381_abnormal_hair_follicle | 2.08888414 |
| 29 | MP0005464_abnormal_platelet_physiology | 2.06871586 |
| 30 | MP0004947_skin_inflammation | 2.03838689 |
| 31 | MP0002006_tumorigenesis | 2.03224012 |
| 32 | MP0000689_abnormal_spleen_morphology | 1.98735561 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.96195207 |
| 34 | MP0002722_abnormal_immune_system | 1.95471649 |
| 35 | MP0005075_abnormal_melanosome_morpholog | 1.95326091 |
| 36 | MP0001845_abnormal_inflammatory_respons | 1.88528556 |
| 37 | MP0006082_CNS_inflammation | 1.88068380 |
| 38 | MP0002429_abnormal_blood_cell | 1.77940527 |
| 39 | MP0001348_abnormal_lacrimal_gland | 1.58588879 |
| 40 | MP0000465_gastrointestinal_hemorrhage | 1.55143415 |
| 41 | MP0002138_abnormal_hepatobiliary_system | 1.53041450 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.46109387 |
| 43 | MP0005379_endocrine/exocrine_gland_phen | 1.39605034 |
| 44 | MP0003300_gastrointestinal_ulcer | 1.39343790 |
| 45 | MP0002163_abnormal_gland_morphology | 1.32396084 |
| 46 | MP0003303_peritoneal_inflammation | 1.27468267 |
| 47 | MP0000490_abnormal_crypts_of | 1.21629928 |
| 48 | MP0002933_joint_inflammation | 1.21587005 |
| 49 | MP0005645_abnormal_hypothalamus_physiol | 1.21074165 |
| 50 | MP0008469_abnormal_protein_level | 1.20741427 |
| 51 | MP0003045_fibrosis | 1.20075289 |
| 52 | MP0005310_abnormal_salivary_gland | 1.19084909 |
| 53 | MP0001853_heart_inflammation | 1.17686680 |
| 54 | MP0002132_abnormal_respiratory_system | 1.15534379 |
| 55 | MP0009764_decreased_sensitivity_to | 1.12368299 |
| 56 | MP0004510_myositis | 1.10538852 |
| 57 | MP0002254_reproductive_system_inflammat | 1.03399438 |
| 58 | MP0003786_premature_aging | 1.00233343 |
| 59 | MP0002396_abnormal_hematopoietic_system | 0.86846175 |
| 60 | MP0003806_abnormal_nucleotide_metabolis | 0.85311353 |
| 61 | MP0002019_abnormal_tumor_incidence | 0.85110018 |
| 62 | MP0001851_eye_inflammation | 0.80773094 |
| 63 | MP0002009_preneoplasia | 0.80527568 |
| 64 | MP0001663_abnormal_digestive_system | 0.77911126 |
| 65 | MP0009763_increased_sensitivity_to | 0.77908925 |
| 66 | MP0003448_altered_tumor_morphology | 0.74912611 |
| 67 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.73615970 |
| 68 | MP0001243_abnormal_dermal_layer | 0.73240304 |
| 69 | MP0002693_abnormal_pancreas_physiology | 0.72670426 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.71475504 |
| 71 | MP0001919_abnormal_reproductive_system | 0.70882141 |
| 72 | MP0004130_abnormal_muscle_cell | 0.69693670 |
| 73 | MP0003172_abnormal_lysosome_physiology | 0.69117420 |
| 74 | MP0002998_abnormal_bone_remodeling | 0.68658251 |
| 75 | MP0003646_muscle_fatigue | 0.68281264 |
| 76 | MP0000858_altered_metastatic_potential | 0.67774459 |
| 77 | MP0009278_abnormal_bone_marrow | 0.63479441 |
| 78 | MP0005166_decreased_susceptibility_to | 0.61999897 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.58407851 |
| 80 | MP0001765_abnormal_ion_homeostasis | 0.58101078 |
| 81 | MP0008995_early_reproductive_senescence | 0.57695315 |
| 82 | MP0009840_abnormal_foam_cell | 0.55470385 |
| 83 | MP0000604_amyloidosis | 0.51690190 |
| 84 | MP0005390_skeleton_phenotype | 0.51636218 |
| 85 | MP0000477_abnormal_intestine_morphology | 0.48279813 |
| 86 | MP0008873_increased_physiological_sensi | 0.47794546 |
| 87 | MP0008961_abnormal_basal_metabolism | 0.46947696 |
| 88 | MP0003795_abnormal_bone_structure | 0.46515217 |
| 89 | MP0003075_altered_response_to | 0.43778351 |
| 90 | MP0002095_abnormal_skin_pigmentation | 0.43377676 |
| 91 | MP0003191_abnormal_cellular_cholesterol | 0.41899520 |
| 92 | MP0005381_digestive/alimentary_phenotyp | 0.40651349 |
| 93 | MP0009642_abnormal_blood_homeostasis | 0.40470396 |
| 94 | MP0002136_abnormal_kidney_physiology | 0.40147060 |
| 95 | MP0008260_abnormal_autophagy | 0.40029712 |
| 96 | MP0005535_abnormal_body_temperature | 0.37725042 |
| 97 | MP0005360_urolithiasis | 0.37712575 |
| 98 | MP0000609_abnormal_liver_physiology | 0.37125880 |
| 99 | MP0009643_abnormal_urine_homeostasis | 0.34128957 |
| 100 | MP0008872_abnormal_physiological_respon | 0.33518784 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.55852555 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.27299284 |
| 3 | Abnormality of T cell number (HP:0011839) | 6.25566589 |
| 4 | Autoimmune hemolytic anemia (HP:0001890) | 6.04890956 |
| 5 | Stomatitis (HP:0010280) | 5.72796943 |
| 6 | Abnormality of T cells (HP:0002843) | 5.21367137 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 5.04536399 |
| 8 | Myositis (HP:0100614) | 5.01233716 |
| 9 | Severe combined immunodeficiency (HP:0004430) | 5.00683881 |
| 10 | IgM deficiency (HP:0002850) | 4.84169819 |
| 11 | IgG deficiency (HP:0004315) | 4.62441900 |
| 12 | Increased IgM level (HP:0003496) | 4.42504316 |
| 13 | Eczematoid dermatitis (HP:0000976) | 4.28007461 |
| 14 | Abnormality of T cell physiology (HP:0011840) | 4.25389098 |
| 15 | Recurrent viral infections (HP:0004429) | 4.06464064 |
| 16 | Recurrent fungal infections (HP:0002841) | 3.94798712 |
| 17 | Combined immunodeficiency (HP:0005387) | 3.93002766 |
| 18 | Aplastic anemia (HP:0001915) | 3.92557332 |
| 19 | Recurrent abscess formation (HP:0002722) | 3.85617319 |
| 20 | Panhypogammaglobulinemia (HP:0003139) | 3.84863982 |
| 21 | Recurrent bacterial skin infections (HP:0005406) | 3.79754639 |
| 22 | Encephalitis (HP:0002383) | 3.72983615 |
| 23 | Abnormality of eosinophils (HP:0001879) | 3.72950092 |
| 24 | Pustule (HP:0200039) | 3.71714347 |
| 25 | Abnormality of macrophages (HP:0004311) | 3.67048930 |
| 26 | Eosinophilia (HP:0001880) | 3.62377034 |
| 27 | Granulocytopenia (HP:0001913) | 3.61632213 |
| 28 | Lymphopenia (HP:0001888) | 3.56549380 |
| 29 | Leukocytosis (HP:0001974) | 3.50793868 |
| 30 | Autoimmune thrombocytopenia (HP:0001973) | 3.46778357 |
| 31 | Meningitis (HP:0001287) | 3.40759034 |
| 32 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.40288831 |
| 33 | Chronic obstructive pulmonary disease (HP:0006510) | 3.27113219 |
| 34 | Obstructive lung disease (HP:0006536) | 3.27113219 |
| 35 | Hypergammaglobulinemia (HP:0010702) | 3.17553065 |
| 36 | Retrobulbar optic neuritis (HP:0100654) | 3.14287823 |
| 37 | Optic neuritis (HP:0100653) | 3.14287823 |
| 38 | Mediastinal lymphadenopathy (HP:0100721) | 3.12659944 |
| 39 | Orchitis (HP:0100796) | 3.10811980 |
| 40 | Pulmonary infiltrates (HP:0002113) | 3.09202131 |
| 41 | Gastrointestinal infarctions (HP:0005244) | 3.09008537 |
| 42 | Vasculitis (HP:0002633) | 3.07381048 |
| 43 | Increased IgE level (HP:0003212) | 3.06213246 |
| 44 | Chronic diarrhea (HP:0002028) | 3.01695306 |
| 45 | Recurrent skin infections (HP:0001581) | 2.97332290 |
| 46 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.96404482 |
| 47 | Recurrent cutaneous fungal infections (HP:0011370) | 2.96404482 |
| 48 | Spontaneous hematomas (HP:0007420) | 2.92650722 |
| 49 | Hypoproteinemia (HP:0003075) | 2.87303730 |
| 50 | Purpura (HP:0000979) | 2.84428240 |
| 51 | Thyroiditis (HP:0100646) | 2.83950364 |
| 52 | Recurrent bronchitis (HP:0002837) | 2.72243558 |
| 53 | Chest pain (HP:0100749) | 2.66142638 |
| 54 | Petechiae (HP:0000967) | 2.65066785 |
| 55 | Lymphoma (HP:0002665) | 2.62486959 |
| 56 | Slow saccadic eye movements (HP:0000514) | 2.61515143 |
| 57 | Joint swelling (HP:0001386) | 2.52063962 |
| 58 | Prolonged bleeding time (HP:0003010) | 2.49120167 |
| 59 | Hemoptysis (HP:0002105) | 2.45929218 |
| 60 | Abnormality of B cell number (HP:0010975) | 2.45745313 |
| 61 | Hypochromic anemia (HP:0001931) | 2.38542104 |
| 62 | Inflammation of the large intestine (HP:0002037) | 2.35093295 |
| 63 | Keratoconjunctivitis sicca (HP:0001097) | 2.33049541 |
| 64 | Verrucae (HP:0200043) | 2.27585868 |
| 65 | Papilloma (HP:0012740) | 2.27585868 |
| 66 | Urticaria (HP:0001025) | 2.25450498 |
| 67 | Epistaxis (HP:0000421) | 2.22882002 |
| 68 | Thrombocytosis (HP:0001894) | 2.22213218 |
| 69 | Microcytic anemia (HP:0001935) | 2.20669685 |
| 70 | Agammaglobulinemia (HP:0004432) | 2.18377829 |
| 71 | Muscle fiber atrophy (HP:0100295) | 2.18312443 |
| 72 | Gastrointestinal inflammation (HP:0004386) | 2.17894706 |
| 73 | Gingival bleeding (HP:0000225) | 2.17005642 |
| 74 | Acute hepatic failure (HP:0006554) | 2.13931612 |
| 75 | Keratoconjunctivitis (HP:0001096) | 2.13229125 |
| 76 | Anorexia (HP:0002039) | 2.11670970 |
| 77 | Abnormality of the prostate (HP:0008775) | 2.05848007 |
| 78 | B lymphocytopenia (HP:0010976) | 2.03497294 |
| 79 | Skin rash (HP:0000988) | 2.00971820 |
| 80 | Increased intramyocellular lipid droplets (HP:0012240) | 2.00409210 |
| 81 | Pulmonary embolism (HP:0002204) | 2.00396864 |
| 82 | Type 2 muscle fiber atrophy (HP:0003554) | 1.99911240 |
| 83 | Chronic otitis media (HP:0000389) | 1.96857532 |
| 84 | Oligomenorrhea (HP:0000876) | 1.94369547 |
| 85 | Hypoplasia of the thymus (HP:0000778) | 1.93700223 |
| 86 | Gangrene (HP:0100758) | 1.89234754 |
| 87 | Hemiplegia (HP:0002301) | 1.88967161 |
| 88 | Bronchitis (HP:0012387) | 1.86508676 |
| 89 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.86223387 |
| 90 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.82658431 |
| 91 | Hypochromic microcytic anemia (HP:0004840) | 1.81705009 |
| 92 | Increased muscle lipid content (HP:0009058) | 1.78484329 |
| 93 | Acne (HP:0001061) | 1.78359316 |
| 94 | Amaurosis fugax (HP:0100576) | 1.75638537 |
| 95 | Pancytopenia (HP:0001876) | 1.73346922 |
| 96 | Sepsis (HP:0100806) | 1.72988763 |
| 97 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.72655769 |
| 98 | Abnormality of the pleura (HP:0002103) | 1.70987985 |
| 99 | Arterial thrombosis (HP:0004420) | 1.69914978 |
| 100 | Arthralgia (HP:0002829) | 1.68211892 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.17906299 |
| 2 | TXK | 4.88594994 |
| 3 | MAP4K1 | 4.11855715 |
| 4 | LATS1 | 3.44597350 |
| 5 | KDR | 3.12968547 |
| 6 | ITK | 2.76425397 |
| 7 | NUAK1 | 2.74837039 |
| 8 | ZAP70 | 2.71912628 |
| 9 | MST4 | 2.68769927 |
| 10 | SCYL2 | 2.62210270 |
| 11 | FES | 2.26625758 |
| 12 | PASK | 2.17964976 |
| 13 | TNK2 | 2.07746198 |
| 14 | GRK6 | 2.05672314 |
| 15 | RIPK4 | 1.97635288 |
| 16 | BTK | 1.89302392 |
| 17 | CSK | 1.77491356 |
| 18 | IKBKE | 1.75030464 |
| 19 | LCK | 1.73049375 |
| 20 | TESK1 | 1.72696321 |
| 21 | TAOK3 | 1.71495295 |
| 22 | SYK | 1.69597411 |
| 23 | MAP2K3 | 1.55641773 |
| 24 | IRAK4 | 1.53171579 |
| 25 | TAOK2 | 1.53125697 |
| 26 | BUB1 | 1.46421802 |
| 27 | TYK2 | 1.45703528 |
| 28 | MAP3K11 | 1.42450557 |
| 29 | PLK4 | 1.40940687 |
| 30 | NLK | 1.40341899 |
| 31 | TBK1 | 1.37717370 |
| 32 | TEC | 1.36502960 |
| 33 | TLK1 | 1.32566617 |
| 34 | JAK3 | 1.32349752 |
| 35 | MAP4K2 | 1.28038706 |
| 36 | CAMKK2 | 1.26834543 |
| 37 | HCK | 1.26163080 |
| 38 | CAMKK1 | 1.24919611 |
| 39 | ZAK | 1.24334413 |
| 40 | TAOK1 | 1.23793590 |
| 41 | CLK1 | 1.23779154 |
| 42 | MAP3K3 | 1.22992108 |
| 43 | JAK1 | 1.19939975 |
| 44 | MAP3K12 | 1.13346054 |
| 45 | IKBKB | 1.08403342 |
| 46 | VRK1 | 1.07667816 |
| 47 | PIK3CG | 1.07525874 |
| 48 | VRK2 | 1.03834572 |
| 49 | LYN | 1.03333052 |
| 50 | PRKCQ | 0.96901534 |
| 51 | PRPF4B | 0.78924842 |
| 52 | BLK | 0.76823312 |
| 53 | EPHB1 | 0.66819787 |
| 54 | PIM1 | 0.65756005 |
| 55 | LIMK1 | 0.63252971 |
| 56 | ADRBK2 | 0.57559425 |
| 57 | CSF1R | 0.57093585 |
| 58 | JAK2 | 0.54604176 |
| 59 | FYN | 0.54296957 |
| 60 | MUSK | 0.53192376 |
| 61 | MAPK11 | 0.52136959 |
| 62 | FGFR4 | 0.50092895 |
| 63 | YES1 | 0.48796634 |
| 64 | SIK3 | 0.48547729 |
| 65 | KIT | 0.48473399 |
| 66 | MAP3K14 | 0.47296952 |
| 67 | SMG1 | 0.45975137 |
| 68 | LRRK2 | 0.45933674 |
| 69 | MAP3K10 | 0.45815373 |
| 70 | RPS6KA5 | 0.44123285 |
| 71 | PDGFRB | 0.42893530 |
| 72 | STK10 | 0.42792923 |
| 73 | MAPK12 | 0.40093210 |
| 74 | FGR | 0.39793327 |
| 75 | BMPR2 | 0.37948106 |
| 76 | PRKCH | 0.36605970 |
| 77 | PDK1 | 0.35433955 |
| 78 | MAP2K6 | 0.34708604 |
| 79 | IGF1R | 0.33166954 |
| 80 | GRK7 | 0.32904638 |
| 81 | MARK3 | 0.32475889 |
| 82 | RPS6KA4 | 0.30888324 |
| 83 | DYRK1B | 0.29499797 |
| 84 | NEK6 | 0.29396913 |
| 85 | MAP3K5 | 0.29249374 |
| 86 | MAP3K13 | 0.28036827 |
| 87 | TRPM7 | 0.27735908 |
| 88 | PTK6 | 0.27092870 |
| 89 | HIPK2 | 0.25633987 |
| 90 | EPHA3 | 0.20980398 |
| 91 | ERN1 | 0.20568220 |
| 92 | MAP3K1 | 0.20367259 |
| 93 | WNK4 | 0.20106077 |
| 94 | TYRO3 | 0.19132207 |
| 95 | FGFR3 | 0.19079821 |
| 96 | CDK4 | 0.18976653 |
| 97 | GRK5 | 0.18973006 |
| 98 | DAPK1 | 0.16494870 |
| 99 | PRKCD | 0.16226601 |
| 100 | IRAK1 | 0.16197292 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.13375822 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.84883818 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.25554079 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.23779264 |
| 5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.20016846 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.14347264 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 3.11362529 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.72389179 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.64660922 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.43679733 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.35091332 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 2.34043188 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.21310427 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.95280337 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.94905238 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.90744793 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.80779960 |
| 18 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.78190496 |
| 19 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.67761582 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.66708679 |
| 21 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.62629599 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.47574344 |
| 23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.43755235 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.41056480 |
| 25 | Shigellosis_Homo sapiens_hsa05131 | 1.38318716 |
| 26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.32585612 |
| 27 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.30913473 |
| 28 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.26440136 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.26025669 |
| 30 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.25008435 |
| 31 | Malaria_Homo sapiens_hsa05144 | 1.22756125 |
| 32 | Leishmaniasis_Homo sapiens_hsa05140 | 1.22296056 |
| 33 | Ribosome_Homo sapiens_hsa03010 | 1.16130427 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.10746539 |
| 35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.10002620 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.08512838 |
| 37 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.02001913 |
| 38 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.00993209 |
| 39 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.94580547 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 0.93334791 |
| 41 | Tuberculosis_Homo sapiens_hsa05152 | 0.90729671 |
| 42 | Influenza A_Homo sapiens_hsa05164 | 0.89681243 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.85664685 |
| 44 | Salmonella infection_Homo sapiens_hsa05132 | 0.84324051 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.83915901 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.83849162 |
| 47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.82320412 |
| 48 | HTLV-I infection_Homo sapiens_hsa05166 | 0.79777784 |
| 49 | Apoptosis_Homo sapiens_hsa04210 | 0.77689463 |
| 50 | Parkinsons disease_Homo sapiens_hsa05012 | 0.77443756 |
| 51 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.74540127 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.71409758 |
| 53 | Hepatitis B_Homo sapiens_hsa05161 | 0.69830743 |
| 54 | Legionellosis_Homo sapiens_hsa05134 | 0.69233590 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65846872 |
| 56 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.62961717 |
| 57 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.61432612 |
| 58 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.60876831 |
| 59 | Endocytosis_Homo sapiens_hsa04144 | 0.58267160 |
| 60 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.57441738 |
| 61 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.55784815 |
| 62 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55109140 |
| 63 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.54447261 |
| 64 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.53595500 |
| 65 | RNA polymerase_Homo sapiens_hsa03020 | 0.52739091 |
| 66 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.51416110 |
| 67 | Pertussis_Homo sapiens_hsa05133 | 0.50313727 |
| 68 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.50045250 |
| 69 | Hepatitis C_Homo sapiens_hsa05160 | 0.44739462 |
| 70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.42493444 |
| 71 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.38266703 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35707189 |
| 73 | Alzheimers disease_Homo sapiens_hsa05010 | 0.35607167 |
| 74 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27426099 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.26814762 |
| 76 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.26275472 |
| 77 | Peroxisome_Homo sapiens_hsa04146 | 0.26178104 |
| 78 | Spliceosome_Homo sapiens_hsa03040 | 0.25490409 |
| 79 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.24268148 |
| 80 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.23274807 |
| 81 | RNA degradation_Homo sapiens_hsa03018 | 0.23150957 |
| 82 | Colorectal cancer_Homo sapiens_hsa05210 | 0.22631129 |
| 83 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.22179113 |
| 84 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.21877924 |
| 85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.20840032 |
| 86 | Phagosome_Homo sapiens_hsa04145 | 0.20180644 |
| 87 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.19335116 |
| 88 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.17891390 |
| 89 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.17370104 |
| 90 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.16848909 |
| 91 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.12046650 |
| 92 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.10600853 |
| 93 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.10547013 |
| 94 | Olfactory transduction_Homo sapiens_hsa04740 | 0.10450252 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.09332059 |
| 96 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.08785791 |
| 97 | Huntingtons disease_Homo sapiens_hsa05016 | 0.07866098 |
| 98 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.04605640 |
| 99 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.04062833 |
| 100 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.03828741 |

