

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of granulocyte differentiation (GO:0030854) | 9.45056379 |
| 2 | negative T cell selection (GO:0043383) | 9.43499552 |
| 3 | V(D)J recombination (GO:0033151) | 9.20877395 |
| 4 | negative thymic T cell selection (GO:0045060) | 8.26828466 |
| 5 | negative regulation of thymocyte apoptotic process (GO:0070244) | 7.54475104 |
| 6 | positive T cell selection (GO:0043368) | 6.85985613 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.64838694 |
| 8 | negative regulation of myotube differentiation (GO:0010832) | 6.23860738 |
| 9 | Peyers patch development (GO:0048541) | 6.22814209 |
| 10 | mucosal-associated lymphoid tissue development (GO:0048537) | 6.22814209 |
| 11 | T cell selection (GO:0045058) | 5.71473424 |
| 12 | regulation of granulocyte differentiation (GO:0030852) | 5.69852577 |
| 13 | thymic T cell selection (GO:0045061) | 5.67271975 |
| 14 | negative regulation of T cell apoptotic process (GO:0070233) | 5.63101710 |
| 15 | T cell migration (GO:0072678) | 5.59237312 |
| 16 | radial glial cell differentiation (GO:0060019) | 5.32609097 |
| 17 | positive thymic T cell selection (GO:0045059) | 5.25473988 |
| 18 | tongue development (GO:0043586) | 5.12721713 |
| 19 | generation of neurons (GO:0048699) | 5.10589230 |
| 20 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.06897667 |
| 21 | positive regulation by host of viral transcription (GO:0043923) | 5.04718360 |
| 22 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 5.00102044 |
| 23 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.90767708 |
| 24 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.81571178 |
| 25 | regulation of interleukin-4 production (GO:0032673) | 4.80465456 |
| 26 | regulation of thymocyte apoptotic process (GO:0070243) | 4.77057897 |
| 27 | regulation of receptor binding (GO:1900120) | 4.56157170 |
| 28 | regulation of interleukin-13 production (GO:0032656) | 4.52794141 |
| 29 | somatic stem cell division (GO:0048103) | 4.47973443 |
| 30 | dentate gyrus development (GO:0021542) | 4.41004436 |
| 31 | apoptotic process involved in morphogenesis (GO:0060561) | 4.34356095 |
| 32 | leukocyte aggregation (GO:0070486) | 4.24730048 |
| 33 | T cell receptor signaling pathway (GO:0050852) | 4.18058031 |
| 34 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 4.16511272 |
| 35 | somatic cell DNA recombination (GO:0016444) | 4.16511272 |
| 36 | developmental pigmentation (GO:0048066) | 4.11083837 |
| 37 | alpha-beta T cell differentiation (GO:0046632) | 4.08990012 |
| 38 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.08872391 |
| 39 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.06724727 |
| 40 | T cell differentiation (GO:0030217) | 4.04504248 |
| 41 | T-helper cell differentiation (GO:0042093) | 4.04413549 |
| 42 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 4.04413549 |
| 43 | regulation of gamma-delta T cell activation (GO:0046643) | 4.02838283 |
| 44 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.94591480 |
| 45 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.93746484 |
| 46 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.90890634 |
| 47 | regulation of interleukin-5 production (GO:0032674) | 3.89032954 |
| 48 | hypothalamus development (GO:0021854) | 3.87898190 |
| 49 | mast cell activation (GO:0045576) | 3.80771780 |
| 50 | regulation of somitogenesis (GO:0014807) | 3.71955962 |
| 51 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.70591560 |
| 52 | granulocyte differentiation (GO:0030851) | 3.70153668 |
| 53 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.69940805 |
| 54 | cellular response to interleukin-4 (GO:0071353) | 3.69196411 |
| 55 | mast cell degranulation (GO:0043303) | 3.68956228 |
| 56 | mast cell activation involved in immune response (GO:0002279) | 3.68956228 |
| 57 | somatic diversification of immune receptors (GO:0002200) | 3.66657075 |
| 58 | regulation of T cell apoptotic process (GO:0070232) | 3.64543343 |
| 59 | regulation of defense response to virus by virus (GO:0050690) | 3.62039865 |
| 60 | modulation by host of symbiont transcription (GO:0052472) | 3.61306794 |
| 61 | modulation by host of viral transcription (GO:0043921) | 3.61306794 |
| 62 | forebrain neuron differentiation (GO:0021879) | 3.60351961 |
| 63 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.55923753 |
| 64 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.55480197 |
| 65 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.55480197 |
| 66 | T cell differentiation involved in immune response (GO:0002292) | 3.55480197 |
| 67 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.54757050 |
| 68 | alpha-beta T cell activation (GO:0046631) | 3.53914362 |
| 69 | mature B cell differentiation involved in immune response (GO:0002313) | 3.51360318 |
| 70 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 3.48307083 |
| 71 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.47757037 |
| 72 | heart trabecula morphogenesis (GO:0061384) | 3.43865703 |
| 73 | positive regulation of alpha-beta T cell activation (GO:0046635) | 3.42952868 |
| 74 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.41353569 |
| 75 | positive regulation of interleukin-4 production (GO:0032753) | 3.40721611 |
| 76 | positive regulation of B cell differentiation (GO:0045579) | 3.40454871 |
| 77 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.38885386 |
| 78 | regulation of histone H3-K9 methylation (GO:0051570) | 3.38006886 |
| 79 | innate immune response in mucosa (GO:0002227) | 3.37407027 |
| 80 | T cell costimulation (GO:0031295) | 3.35712558 |
| 81 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.35391443 |
| 82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.33303864 |
| 83 | lymphocyte costimulation (GO:0031294) | 3.32816930 |
| 84 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.30659432 |
| 85 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.24547117 |
| 86 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.17771663 |
| 87 | apoptotic process involved in development (GO:1902742) | 3.16699179 |
| 88 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.16637902 |
| 89 | response to interleukin-4 (GO:0070670) | 3.11711223 |
| 90 | heart valve formation (GO:0003188) | 3.09146728 |
| 91 | negative regulation of striated muscle cell differentiation (GO:0051154) | 3.09054111 |
| 92 | T cell activation (GO:0042110) | 3.06806434 |
| 93 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 3.05960777 |
| 94 | B cell proliferation (GO:0042100) | 3.02935518 |
| 95 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.01905638 |
| 96 | negative regulation of cell killing (GO:0031342) | 3.01905638 |
| 97 | developmental programmed cell death (GO:0010623) | 2.98175154 |
| 98 | regulation of alpha-beta T cell activation (GO:0046634) | 2.98168227 |
| 99 | anatomical structure regression (GO:0060033) | 2.97599694 |
| 100 | mitotic chromosome condensation (GO:0007076) | 2.96966364 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.51947479 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 8.37466996 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.91135553 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.50091477 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.37352821 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.67001506 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.55821091 |
| 8 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.37232740 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.96517528 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 2.79026134 |
| 11 | UTX_26944678_Chip-Seq_JUKART_Human | 2.78001128 |
| 12 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.77294106 |
| 13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.66248662 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.63482762 |
| 15 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.55628606 |
| 16 | MYC_22102868_ChIP-Seq_BL_Human | 2.54397694 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.38138149 |
| 18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.38089948 |
| 19 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.31012095 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.25980315 |
| 21 | MYB_26560356_Chip-Seq_TH1_Human | 2.19063862 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.13989029 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.01892451 |
| 24 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.93698138 |
| 25 | MAF_26560356_Chip-Seq_TH1_Human | 1.93538969 |
| 26 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.91195596 |
| 27 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.86177778 |
| 28 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.85992256 |
| 29 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.85663398 |
| 30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.85444661 |
| 31 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.78929266 |
| 32 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.77098215 |
| 33 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.74921367 |
| 34 | MAF_26560356_Chip-Seq_TH2_Human | 1.72016941 |
| 35 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.66594202 |
| 36 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.57540790 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.51453885 |
| 38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.50389862 |
| 39 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.50228231 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.49400535 |
| 41 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.47611001 |
| 42 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.45365125 |
| 43 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.40389853 |
| 44 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.39163476 |
| 45 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.38750692 |
| 46 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.34003766 |
| 47 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32953446 |
| 48 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.31108770 |
| 49 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29477155 |
| 50 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.27858227 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23194356 |
| 52 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.22805446 |
| 53 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.20691804 |
| 54 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20374047 |
| 55 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.16244236 |
| 56 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.15725283 |
| 57 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.13764235 |
| 58 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13457523 |
| 59 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.12620198 |
| 60 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12606877 |
| 61 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.12501184 |
| 62 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.12051280 |
| 63 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.06173542 |
| 64 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.04606760 |
| 65 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.04494028 |
| 66 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.03430494 |
| 67 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01823070 |
| 68 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.01799214 |
| 69 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.99838360 |
| 70 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.99533176 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98857210 |
| 72 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.98595355 |
| 73 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.97945501 |
| 74 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.97112413 |
| 75 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.96893223 |
| 76 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.96293575 |
| 77 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.95635166 |
| 78 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94860888 |
| 79 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.94479510 |
| 80 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.94075582 |
| 81 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.93041565 |
| 82 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.92721831 |
| 83 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.91912457 |
| 84 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.87862659 |
| 85 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85411042 |
| 86 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.85005814 |
| 87 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.84400169 |
| 88 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.83901585 |
| 89 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.83324476 |
| 90 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.82935157 |
| 91 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81035407 |
| 92 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.79070261 |
| 93 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.78815449 |
| 94 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73787938 |
| 95 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.71701015 |
| 96 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.71528864 |
| 97 | SPI1_23127762_ChIP-Seq_K562_Human | 0.71206592 |
| 98 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.70067730 |
| 99 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.69606721 |
| 100 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.69268058 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004381_abnormal_hair_follicle | 7.16891074 |
| 2 | MP0003763_abnormal_thymus_physiology | 6.72118143 |
| 3 | MP0005671_abnormal_response_to | 4.51972984 |
| 4 | MP0002396_abnormal_hematopoietic_system | 4.19905503 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 4.12672672 |
| 6 | MP0000703_abnormal_thymus_morphology | 3.42068533 |
| 7 | MP0009697_abnormal_copulation | 2.59406657 |
| 8 | MP0000685_abnormal_immune_system | 2.42954357 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.39445915 |
| 10 | MP0002405_respiratory_system_inflammati | 2.37407283 |
| 11 | MP0002398_abnormal_bone_marrow | 2.30488998 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.26187323 |
| 13 | MP0003646_muscle_fatigue | 2.23840421 |
| 14 | MP0001800_abnormal_humoral_immune | 2.14069145 |
| 15 | MP0005000_abnormal_immune_tolerance | 2.12705557 |
| 16 | MP0002009_preneoplasia | 2.12606469 |
| 17 | MP0002722_abnormal_immune_system | 2.05810756 |
| 18 | MP0008877_abnormal_DNA_methylation | 2.00801355 |
| 19 | MP0002420_abnormal_adaptive_immunity | 1.99479277 |
| 20 | MP0001819_abnormal_immune_cell | 1.91724988 |
| 21 | MP0000716_abnormal_immune_system | 1.85962020 |
| 22 | MP0002166_altered_tumor_susceptibility | 1.84910851 |
| 23 | MP0009785_altered_susceptibility_to | 1.83164575 |
| 24 | MP0003724_increased_susceptibility_to | 1.81304159 |
| 25 | MP0008057_abnormal_DNA_replication | 1.75870371 |
| 26 | MP0001835_abnormal_antigen_presentation | 1.75429487 |
| 27 | MP0000689_abnormal_spleen_morphology | 1.73153625 |
| 28 | MP0005025_abnormal_response_to | 1.71428707 |
| 29 | MP0002723_abnormal_immune_serum | 1.67965732 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.65425277 |
| 31 | MP0001243_abnormal_dermal_layer | 1.64005080 |
| 32 | MP0002429_abnormal_blood_cell | 1.49508395 |
| 33 | MP0004947_skin_inflammation | 1.49387059 |
| 34 | MP0002452_abnormal_antigen_presenting | 1.48561487 |
| 35 | MP0003436_decreased_susceptibility_to | 1.46457126 |
| 36 | MP0003111_abnormal_nucleus_morphology | 1.34741872 |
| 37 | MP0000015_abnormal_ear_pigmentation | 1.32776280 |
| 38 | MP0002148_abnormal_hypersensitivity_rea | 1.32500754 |
| 39 | MP0003866_abnormal_defecation | 1.32014986 |
| 40 | MP0002006_tumorigenesis | 1.31789321 |
| 41 | MP0004957_abnormal_blastocyst_morpholog | 1.30531951 |
| 42 | MP0002098_abnormal_vibrissa_morphology | 1.30120233 |
| 43 | MP0010155_abnormal_intestine_physiology | 1.25510432 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.24855605 |
| 45 | MP0003878_abnormal_ear_physiology | 1.24855605 |
| 46 | MP0002933_joint_inflammation | 1.23765716 |
| 47 | MP0001919_abnormal_reproductive_system | 1.22679315 |
| 48 | MP0005464_abnormal_platelet_physiology | 1.18887558 |
| 49 | MP0005387_immune_system_phenotype | 1.15706466 |
| 50 | MP0001790_abnormal_immune_system | 1.15706466 |
| 51 | MP0003252_abnormal_bile_duct | 1.13489398 |
| 52 | MP0003011_delayed_dark_adaptation | 1.10468877 |
| 53 | MP0002019_abnormal_tumor_incidence | 1.08868136 |
| 54 | MP0000490_abnormal_crypts_of | 1.07152168 |
| 55 | MP0003300_gastrointestinal_ulcer | 1.06217381 |
| 56 | MP0002095_abnormal_skin_pigmentation | 0.99883797 |
| 57 | MP0005645_abnormal_hypothalamus_physiol | 0.97302630 |
| 58 | MP0003077_abnormal_cell_cycle | 0.97234566 |
| 59 | MP0009278_abnormal_bone_marrow | 0.94260786 |
| 60 | MP0002877_abnormal_melanocyte_morpholog | 0.93204690 |
| 61 | MP0004130_abnormal_muscle_cell | 0.92252254 |
| 62 | MP0001845_abnormal_inflammatory_respons | 0.92034478 |
| 63 | MP0005360_urolithiasis | 0.90299814 |
| 64 | MP0002163_abnormal_gland_morphology | 0.85137001 |
| 65 | MP0002419_abnormal_innate_immunity | 0.80588221 |
| 66 | MP0001730_embryonic_growth_arrest | 0.80578179 |
| 67 | MP0003787_abnormal_imprinting | 0.77151414 |
| 68 | MP0000465_gastrointestinal_hemorrhage | 0.74093628 |
| 69 | MP0008058_abnormal_DNA_repair | 0.72618146 |
| 70 | MP0005389_reproductive_system_phenotype | 0.72362144 |
| 71 | MP0004145_abnormal_muscle_electrophysio | 0.72281441 |
| 72 | MP0001661_extended_life_span | 0.72272559 |
| 73 | MP0001765_abnormal_ion_homeostasis | 0.71823402 |
| 74 | MP0004185_abnormal_adipocyte_glucose | 0.69333533 |
| 75 | MP0004043_abnormal_pH_regulation | 0.67639187 |
| 76 | MP0010307_abnormal_tumor_latency | 0.65329891 |
| 77 | MP0001873_stomach_inflammation | 0.65016959 |
| 78 | MP0000627_abnormal_mammary_gland | 0.64999021 |
| 79 | MP0005310_abnormal_salivary_gland | 0.64655458 |
| 80 | MP0001879_abnormal_lymphatic_vessel | 0.63394825 |
| 81 | MP0002970_abnormal_white_adipose | 0.62607484 |
| 82 | MP0005647_abnormal_sex_gland | 0.61122209 |
| 83 | MP0003045_fibrosis | 0.60659370 |
| 84 | MP0000313_abnormal_cell_death | 0.59127648 |
| 85 | MP0005365_abnormal_bile_salt | 0.55360997 |
| 86 | MP0002693_abnormal_pancreas_physiology | 0.54678491 |
| 87 | MP0000377_abnormal_hair_follicle | 0.54168214 |
| 88 | MP0002638_abnormal_pupillary_reflex | 0.53879107 |
| 89 | MP0008961_abnormal_basal_metabolism | 0.51701813 |
| 90 | MP0003448_altered_tumor_morphology | 0.51557176 |
| 91 | MP0008995_early_reproductive_senescence | 0.50344493 |
| 92 | MP0009931_abnormal_skin_appearance | 0.49489172 |
| 93 | MP0001853_heart_inflammation | 0.49196212 |
| 94 | MP0004808_abnormal_hematopoietic_stem | 0.48744306 |
| 95 | MP0002136_abnormal_kidney_physiology | 0.47911517 |
| 96 | MP0004264_abnormal_extraembryonic_tissu | 0.47618982 |
| 97 | MP0002876_abnormal_thyroid_physiology | 0.47084615 |
| 98 | MP0003191_abnormal_cellular_cholesterol | 0.46210074 |
| 99 | MP0001756_abnormal_urination | 0.45221379 |
| 100 | MP0004036_abnormal_muscle_relaxation | 0.44984651 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Severe combined immunodeficiency (HP:0004430) | 9.68343311 |
| 2 | Combined immunodeficiency (HP:0005387) | 8.30705355 |
| 3 | B lymphocytopenia (HP:0010976) | 7.72263087 |
| 4 | Abnormality of B cell number (HP:0010975) | 7.12809236 |
| 5 | Thyroiditis (HP:0100646) | 6.96936884 |
| 6 | Panhypogammaglobulinemia (HP:0003139) | 6.39166706 |
| 7 | Autoimmune hemolytic anemia (HP:0001890) | 6.32267558 |
| 8 | T lymphocytopenia (HP:0005403) | 5.84721579 |
| 9 | Autoimmune thrombocytopenia (HP:0001973) | 5.21209534 |
| 10 | Abnormality of T cell number (HP:0011839) | 5.05025099 |
| 11 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.82883463 |
| 12 | Subaortic stenosis (HP:0001682) | 4.82883463 |
| 13 | Abnormality of the columella (HP:0009929) | 4.44803931 |
| 14 | Abnormality of T cells (HP:0002843) | 3.84415378 |
| 15 | Hypoplasia of the thymus (HP:0000778) | 3.79053642 |
| 16 | Broad face (HP:0000283) | 3.76404691 |
| 17 | IgG deficiency (HP:0004315) | 3.66051507 |
| 18 | Recurrent viral infections (HP:0004429) | 3.65685680 |
| 19 | Eosinophilia (HP:0001880) | 3.65600180 |
| 20 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.63405243 |
| 21 | Increased IgE level (HP:0003212) | 3.63034520 |
| 22 | Recurrent fungal infections (HP:0002841) | 3.56445459 |
| 23 | Abnormality of eosinophils (HP:0001879) | 3.48374133 |
| 24 | Eczematoid dermatitis (HP:0000976) | 3.41360469 |
| 25 | Embryonal renal neoplasm (HP:0011794) | 3.39058126 |
| 26 | Aplastic anemia (HP:0001915) | 3.37845193 |
| 27 | Lymphopenia (HP:0001888) | 3.15663285 |
| 28 | Granulocytopenia (HP:0001913) | 3.10974662 |
| 29 | Hypoproteinemia (HP:0003075) | 3.08620797 |
| 30 | Aplasia cutis congenita (HP:0001057) | 3.07025017 |
| 31 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.89706618 |
| 32 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.81297731 |
| 33 | Lymphoma (HP:0002665) | 2.80805032 |
| 34 | Acute lymphatic leukemia (HP:0006721) | 2.80269474 |
| 35 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.77230106 |
| 36 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.77119955 |
| 37 | IgM deficiency (HP:0002850) | 2.74500111 |
| 38 | Chronic diarrhea (HP:0002028) | 2.69241200 |
| 39 | Mesangial abnormality (HP:0001966) | 2.49330352 |
| 40 | Reduced antithrombin III activity (HP:0001976) | 2.46443936 |
| 41 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.45995347 |
| 42 | Spontaneous hematomas (HP:0007420) | 2.44412906 |
| 43 | Chromsome breakage (HP:0040012) | 2.43393297 |
| 44 | Leukocytosis (HP:0001974) | 2.43305370 |
| 45 | Pigmentary retinal degeneration (HP:0001146) | 2.40648537 |
| 46 | Prostate neoplasm (HP:0100787) | 2.36242952 |
| 47 | Volvulus (HP:0002580) | 2.29780444 |
| 48 | Inflammation of the large intestine (HP:0002037) | 2.28456224 |
| 49 | Colon cancer (HP:0003003) | 2.28268463 |
| 50 | Gastrointestinal inflammation (HP:0004386) | 2.23037521 |
| 51 | Abnormality of the thymus (HP:0000777) | 2.18678026 |
| 52 | Abnormality of T cell physiology (HP:0011840) | 2.18247489 |
| 53 | Hematochezia (HP:0002573) | 2.13570272 |
| 54 | Abnormality of chromosome segregation (HP:0002916) | 2.12768224 |
| 55 | Embryonal neoplasm (HP:0002898) | 2.12151428 |
| 56 | Meningitis (HP:0001287) | 2.10604779 |
| 57 | Abnormality of homocysteine metabolism (HP:0010919) | 2.10523637 |
| 58 | Homocystinuria (HP:0002156) | 2.10523637 |
| 59 | Adactyly (HP:0009776) | 2.07384118 |
| 60 | Encephalitis (HP:0002383) | 2.05929330 |
| 61 | Skull defect (HP:0001362) | 1.95257235 |
| 62 | Increased circulating renin level (HP:0000848) | 1.94573641 |
| 63 | Cutis marmorata (HP:0000965) | 1.91197706 |
| 64 | Tetany (HP:0001281) | 1.90582547 |
| 65 | Abnormality of the prostate (HP:0008775) | 1.89511305 |
| 66 | Stomatitis (HP:0010280) | 1.89317907 |
| 67 | Prominent nose (HP:0000448) | 1.86687016 |
| 68 | Amaurosis fugax (HP:0100576) | 1.84867942 |
| 69 | Colitis (HP:0002583) | 1.83039445 |
| 70 | Abnormality of the ileum (HP:0001549) | 1.81271982 |
| 71 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.76873522 |
| 72 | Recurrent cutaneous fungal infections (HP:0011370) | 1.75201449 |
| 73 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.75201449 |
| 74 | Abnormality of chromosome stability (HP:0003220) | 1.73952993 |
| 75 | Pseudobulbar signs (HP:0002200) | 1.72853186 |
| 76 | Cavernous hemangioma (HP:0001048) | 1.68769259 |
| 77 | Porencephaly (HP:0002132) | 1.64104407 |
| 78 | Dysphonia (HP:0001618) | 1.61895415 |
| 79 | Hypomagnesemia (HP:0002917) | 1.59151988 |
| 80 | Gastrointestinal infarctions (HP:0005244) | 1.59058539 |
| 81 | Absent thumb (HP:0009777) | 1.58227625 |
| 82 | Abnormality of the right ventricle (HP:0001707) | 1.56536003 |
| 83 | Increased IgM level (HP:0003496) | 1.54688914 |
| 84 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.54040130 |
| 85 | Abnormality of the preputium (HP:0100587) | 1.52181898 |
| 86 | Hyperlipoproteinemia (HP:0010980) | 1.51930029 |
| 87 | Trigonocephaly (HP:0000243) | 1.51148538 |
| 88 | Duodenal stenosis (HP:0100867) | 1.50864008 |
| 89 | Small intestinal stenosis (HP:0012848) | 1.50864008 |
| 90 | Myelodysplasia (HP:0002863) | 1.49938540 |
| 91 | Hypergammaglobulinemia (HP:0010702) | 1.47816964 |
| 92 | Abnormality of the parietal bone (HP:0002696) | 1.45538406 |
| 93 | Sepsis (HP:0100806) | 1.42284332 |
| 94 | Reticulocytopenia (HP:0001896) | 1.41606902 |
| 95 | Basal cell carcinoma (HP:0002671) | 1.41280258 |
| 96 | Cupped ribs (HP:0000887) | 1.40984542 |
| 97 | Vasculitis (HP:0002633) | 1.40482897 |
| 98 | Pancytopenia (HP:0001876) | 1.39526714 |
| 99 | Chronic obstructive pulmonary disease (HP:0006510) | 1.39245955 |
| 100 | Obstructive lung disease (HP:0006536) | 1.39245955 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NLK | 5.90295453 |
| 2 | TESK2 | 5.74613369 |
| 3 | TXK | 4.10887742 |
| 4 | MAP3K10 | 3.30002554 |
| 5 | PASK | 3.10115328 |
| 6 | CDK12 | 3.00992065 |
| 7 | SCYL2 | 2.97265616 |
| 8 | ZAP70 | 2.53508570 |
| 9 | MAP4K1 | 2.21662417 |
| 10 | TLK1 | 2.17317008 |
| 11 | CAMKK1 | 2.17030429 |
| 12 | ZAK | 2.02265780 |
| 13 | ITK | 1.99072818 |
| 14 | VRK1 | 1.94593511 |
| 15 | MUSK | 1.90256846 |
| 16 | RPS6KA4 | 1.87561326 |
| 17 | BTK | 1.85859265 |
| 18 | MAP3K12 | 1.78228489 |
| 19 | TAF1 | 1.68020314 |
| 20 | RPS6KA5 | 1.51872694 |
| 21 | CAMKK2 | 1.51379400 |
| 22 | SMG1 | 1.47184605 |
| 23 | CDC7 | 1.45855468 |
| 24 | MAP3K7 | 1.45673533 |
| 25 | KDR | 1.39691282 |
| 26 | MAP3K11 | 1.37744133 |
| 27 | SYK | 1.36305015 |
| 28 | BRD4 | 1.30110459 |
| 29 | GRK6 | 1.24937922 |
| 30 | CLK1 | 1.24131413 |
| 31 | PIK3CG | 1.21284724 |
| 32 | ICK | 1.15716403 |
| 33 | CDK7 | 1.14737042 |
| 34 | CAMK1 | 1.13914564 |
| 35 | BUB1 | 1.13656181 |
| 36 | MAP3K3 | 1.11290115 |
| 37 | TESK1 | 1.06544978 |
| 38 | LCK | 0.99801262 |
| 39 | VRK2 | 0.99497269 |
| 40 | CDK6 | 0.98912987 |
| 41 | TNK2 | 0.96046378 |
| 42 | CAMK4 | 0.95280332 |
| 43 | CDK3 | 0.92282794 |
| 44 | MELK | 0.92190294 |
| 45 | CDK4 | 0.92170255 |
| 46 | FES | 0.91800986 |
| 47 | TEC | 0.89599668 |
| 48 | CSK | 0.84479057 |
| 49 | MAPK11 | 0.84207401 |
| 50 | DAPK3 | 0.82643332 |
| 51 | PRPF4B | 0.82208311 |
| 52 | PRKCQ | 0.82164792 |
| 53 | STK4 | 0.78532235 |
| 54 | CHEK2 | 0.77148266 |
| 55 | MARK2 | 0.72746606 |
| 56 | MST4 | 0.69437694 |
| 57 | LYN | 0.65860888 |
| 58 | PIM1 | 0.62615441 |
| 59 | AURKB | 0.62290436 |
| 60 | MAPK13 | 0.60481941 |
| 61 | TAOK2 | 0.60230487 |
| 62 | HCK | 0.59923909 |
| 63 | ATR | 0.59190500 |
| 64 | AURKA | 0.55364076 |
| 65 | BRSK1 | 0.52445126 |
| 66 | TAOK1 | 0.50002347 |
| 67 | NEK6 | 0.49988711 |
| 68 | RIPK1 | 0.49845973 |
| 69 | RPS6KB2 | 0.49030739 |
| 70 | IKBKE | 0.47975143 |
| 71 | TRIB3 | 0.43094553 |
| 72 | CHEK1 | 0.38043261 |
| 73 | FYN | 0.37275783 |
| 74 | PLK4 | 0.36856207 |
| 75 | NUAK1 | 0.35901941 |
| 76 | TTK | 0.35800329 |
| 77 | CDK9 | 0.34506644 |
| 78 | TYK2 | 0.34044321 |
| 79 | PDGFRB | 0.32871788 |
| 80 | CDK8 | 0.30928176 |
| 81 | TAOK3 | 0.29083452 |
| 82 | MAP3K2 | 0.28651469 |
| 83 | PIM2 | 0.27980464 |
| 84 | FGFR2 | 0.26925997 |
| 85 | SGK3 | 0.25202718 |
| 86 | MAP2K3 | 0.24748592 |
| 87 | ATM | 0.24302402 |
| 88 | HIPK2 | 0.23236983 |
| 89 | PRKCB | 0.22427144 |
| 90 | IRAK4 | 0.20317563 |
| 91 | RAF1 | 0.18905040 |
| 92 | MAP3K9 | 0.17971819 |
| 93 | CDK2 | 0.17719837 |
| 94 | CSF1R | 0.17487425 |
| 95 | CDK1 | 0.16136453 |
| 96 | RPS6KL1 | 0.16056222 |
| 97 | RPS6KC1 | 0.16056222 |
| 98 | WNK1 | 0.14801510 |
| 99 | SGK2 | 0.14662519 |
| 100 | RPS6KA6 | 0.14514335 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 6.70060133 |
| 2 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 5.37622975 |
| 3 | Alcoholism_Homo sapiens_hsa05034 | 3.95835272 |
| 4 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.32866494 |
| 5 | Thyroid cancer_Homo sapiens_hsa05216 | 3.08371612 |
| 6 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.96620778 |
| 7 | Viral carcinogenesis_Homo sapiens_hsa05203 | 2.63198266 |
| 8 | Cell cycle_Homo sapiens_hsa04110 | 2.53027996 |
| 9 | DNA replication_Homo sapiens_hsa03030 | 2.35154571 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.27965097 |
| 11 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.91064310 |
| 12 | Measles_Homo sapiens_hsa05162 | 1.87660635 |
| 13 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.61782670 |
| 14 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.60859206 |
| 15 | Colorectal cancer_Homo sapiens_hsa05210 | 1.58500960 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.58315657 |
| 17 | Endometrial cancer_Homo sapiens_hsa05213 | 1.54892459 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.53400842 |
| 19 | Prostate cancer_Homo sapiens_hsa05215 | 1.39658123 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.37562170 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.36005866 |
| 22 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.34027567 |
| 23 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.33115278 |
| 24 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.31492634 |
| 25 | Glioma_Homo sapiens_hsa05214 | 1.26799762 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26123587 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.24391050 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.22371464 |
| 29 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.21191633 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.05938892 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.02941206 |
| 32 | HTLV-I infection_Homo sapiens_hsa05166 | 1.01843730 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.01131465 |
| 34 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.93740088 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 0.93376477 |
| 36 | Ribosome_Homo sapiens_hsa03010 | 0.90573552 |
| 37 | Proteasome_Homo sapiens_hsa03050 | 0.90572348 |
| 38 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.88393616 |
| 39 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.88301274 |
| 40 | Hepatitis B_Homo sapiens_hsa05161 | 0.87245720 |
| 41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86148397 |
| 42 | Melanoma_Homo sapiens_hsa05218 | 0.83641179 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83198853 |
| 44 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.80166264 |
| 45 | RNA polymerase_Homo sapiens_hsa03020 | 0.80130347 |
| 46 | Malaria_Homo sapiens_hsa05144 | 0.79842183 |
| 47 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.78374382 |
| 48 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.78024155 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77195310 |
| 50 | Adherens junction_Homo sapiens_hsa04520 | 0.72282643 |
| 51 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.72179361 |
| 52 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.71112453 |
| 53 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.69606360 |
| 54 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.69599325 |
| 55 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.69247553 |
| 56 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.68951634 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66359539 |
| 58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.64133662 |
| 59 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.62486055 |
| 60 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.61879269 |
| 61 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.57406199 |
| 62 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.55824511 |
| 63 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.52647991 |
| 64 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.49974371 |
| 65 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.49840997 |
| 66 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.49433254 |
| 67 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.44356552 |
| 68 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.41989535 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.40421515 |
| 70 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.38186165 |
| 71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.38084940 |
| 72 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37584661 |
| 73 | Melanogenesis_Homo sapiens_hsa04916 | 0.37075890 |
| 74 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36068709 |
| 75 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.34777700 |
| 76 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.33438615 |
| 77 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.32586814 |
| 78 | Basal transcription factors_Homo sapiens_hsa03022 | 0.31844198 |
| 79 | Purine metabolism_Homo sapiens_hsa00230 | 0.31279693 |
| 80 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.30876982 |
| 81 | RNA degradation_Homo sapiens_hsa03018 | 0.30302101 |
| 82 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.28340973 |
| 83 | Prion diseases_Homo sapiens_hsa05020 | 0.28323618 |
| 84 | Olfactory transduction_Homo sapiens_hsa04740 | 0.27666505 |
| 85 | Platelet activation_Homo sapiens_hsa04611 | 0.27012244 |
| 86 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.25082857 |
| 87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.24422629 |
| 88 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.22680519 |
| 89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.22234167 |
| 90 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.21524669 |
| 91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.20610228 |
| 92 | Pathways in cancer_Homo sapiens_hsa05200 | 0.20396360 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.18929997 |
| 94 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.17376574 |
| 95 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.17342490 |
| 96 | Shigellosis_Homo sapiens_hsa05131 | 0.16657459 |
| 97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.15096646 |
| 98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.13379134 |
| 99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.13376313 |
| 100 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.12913245 |

