

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative T cell selection (GO:0043383) | 7.36475299 |
| 2 | negative thymic T cell selection (GO:0045060) | 6.91567638 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.60072096 |
| 4 | tolerance induction (GO:0002507) | 6.41265068 |
| 5 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.20440759 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.06921506 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.04148130 |
| 8 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.99795160 |
| 9 | negative regulation of cell killing (GO:0031342) | 5.99795160 |
| 10 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.79357903 |
| 11 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.68191252 |
| 12 | thymic T cell selection (GO:0045061) | 5.63030149 |
| 13 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.52674098 |
| 14 | positive T cell selection (GO:0043368) | 5.49431258 |
| 15 | regulation of T cell tolerance induction (GO:0002664) | 5.38751482 |
| 16 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.37986747 |
| 17 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 5.37016518 |
| 18 | T cell selection (GO:0045058) | 5.33739972 |
| 19 | cellular response to interleukin-15 (GO:0071350) | 5.25723251 |
| 20 | regulation of regulatory T cell differentiation (GO:0045589) | 5.21153962 |
| 21 | positive regulation of granulocyte differentiation (GO:0030854) | 5.20040173 |
| 22 | response to interleukin-15 (GO:0070672) | 5.15139024 |
| 23 | positive regulation of tolerance induction (GO:0002645) | 5.05513100 |
| 24 | positive thymic T cell selection (GO:0045059) | 5.02761837 |
| 25 | regulation of gamma-delta T cell activation (GO:0046643) | 4.87597906 |
| 26 | leukocyte aggregation (GO:0070486) | 4.83330347 |
| 27 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.81551723 |
| 28 | activated T cell proliferation (GO:0050798) | 4.80295729 |
| 29 | regulation of tolerance induction (GO:0002643) | 4.56055889 |
| 30 | NIK/NF-kappaB signaling (GO:0038061) | 4.48883684 |
| 31 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.42745760 |
| 32 | T cell migration (GO:0072678) | 4.35583733 |
| 33 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.28115450 |
| 34 | positive regulation of T cell differentiation in thymus (GO:0033089) | 4.25417289 |
| 35 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.24089282 |
| 36 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.24089282 |
| 37 | negative regulation of T cell mediated immunity (GO:0002710) | 4.19643717 |
| 38 | T cell receptor signaling pathway (GO:0050852) | 4.12602924 |
| 39 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.04553776 |
| 40 | alpha-beta T cell differentiation (GO:0046632) | 3.97650459 |
| 41 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.91225012 |
| 42 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.88943150 |
| 43 | interferon-gamma production (GO:0032609) | 3.88937151 |
| 44 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.76245881 |
| 45 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.76212742 |
| 46 | positive regulation of interleukin-4 production (GO:0032753) | 3.75019068 |
| 47 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.72028554 |
| 48 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.70374646 |
| 49 | mast cell activation (GO:0045576) | 3.67003810 |
| 50 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.65710857 |
| 51 | positive regulation of isotype switching (GO:0045830) | 3.65639944 |
| 52 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.65125776 |
| 53 | T cell homeostasis (GO:0043029) | 3.57228212 |
| 54 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.55991985 |
| 55 | alpha-beta T cell activation (GO:0046631) | 3.54943079 |
| 56 | positive regulation of cell killing (GO:0031343) | 3.52158849 |
| 57 | lymphocyte costimulation (GO:0031294) | 3.52115538 |
| 58 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.51387185 |
| 59 | regulation of granulocyte differentiation (GO:0030852) | 3.49143976 |
| 60 | T cell costimulation (GO:0031295) | 3.48101258 |
| 61 | regulation of cell killing (GO:0031341) | 3.46125638 |
| 62 | regulation of chronic inflammatory response (GO:0002676) | 3.46124457 |
| 63 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.42930249 |
| 64 | T-helper cell differentiation (GO:0042093) | 3.42930249 |
| 65 | regulation of interleukin-4 production (GO:0032673) | 3.39446117 |
| 66 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.37322107 |
| 67 | positive regulation of DNA recombination (GO:0045911) | 3.36396716 |
| 68 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.32815480 |
| 69 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.31803386 |
| 70 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.31803386 |
| 71 | T cell differentiation involved in immune response (GO:0002292) | 3.31803386 |
| 72 | positive regulation of interleukin-2 production (GO:0032743) | 3.31678057 |
| 73 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.31486463 |
| 74 | T cell differentiation (GO:0030217) | 3.31379085 |
| 75 | cytidine metabolic process (GO:0046087) | 3.30204334 |
| 76 | cytidine catabolic process (GO:0006216) | 3.30204334 |
| 77 | cytidine deamination (GO:0009972) | 3.30204334 |
| 78 | regulation of B cell differentiation (GO:0045577) | 3.29686340 |
| 79 | positive regulation of B cell differentiation (GO:0045579) | 3.28601649 |
| 80 | regulation of defense response to virus by virus (GO:0050690) | 3.28327054 |
| 81 | regulation of isotype switching (GO:0045191) | 3.25600710 |
| 82 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.23456646 |
| 83 | signal complex assembly (GO:0007172) | 3.19501835 |
| 84 | regulation of alpha-beta T cell activation (GO:0046634) | 3.17141967 |
| 85 | cellular response to type I interferon (GO:0071357) | 3.15047060 |
| 86 | type I interferon signaling pathway (GO:0060337) | 3.15047060 |
| 87 | negative regulation of interleukin-12 production (GO:0032695) | 3.13720088 |
| 88 | response to type I interferon (GO:0034340) | 3.13226315 |
| 89 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.12838558 |
| 90 | negative regulation of T cell apoptotic process (GO:0070233) | 3.09121991 |
| 91 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.06749987 |
| 92 | positive regulation of B cell mediated immunity (GO:0002714) | 3.04167802 |
| 93 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.04167802 |
| 94 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.03776018 |
| 95 | regulation of thymocyte apoptotic process (GO:0070243) | 3.03664429 |
| 96 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.03480445 |
| 97 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.03440810 |
| 98 | B cell receptor signaling pathway (GO:0050853) | 3.02845382 |
| 99 | myeloid dendritic cell differentiation (GO:0043011) | 3.02779073 |
| 100 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.02196773 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.03199359 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.64939988 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.07867316 |
| 4 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.97547973 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.94459339 |
| 6 | MYB_26560356_Chip-Seq_TH2_Human | 3.67020366 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.37746363 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.32288180 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.14476548 |
| 10 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.11368842 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.07761465 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.02899155 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.99030521 |
| 14 | MAF_26560356_Chip-Seq_TH1_Human | 2.93720256 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.92922290 |
| 16 | MYB_26560356_Chip-Seq_TH1_Human | 2.88006323 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.83533449 |
| 18 | UTX_26944678_Chip-Seq_JUKART_Human | 2.82595184 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.69146600 |
| 20 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.49738492 |
| 21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.48143837 |
| 22 | MAF_26560356_Chip-Seq_TH2_Human | 2.28536634 |
| 23 | MYC_22102868_ChIP-Seq_BL_Human | 2.14886455 |
| 24 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.12731196 |
| 25 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.08952024 |
| 26 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.08679756 |
| 27 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.96786175 |
| 28 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.95675351 |
| 29 | GATA3_26560356_Chip-Seq_TH2_Human | 1.93767126 |
| 30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.89463726 |
| 31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.89129973 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.81956469 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80824594 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80159662 |
| 35 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.79940022 |
| 36 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.73934942 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.72311008 |
| 38 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.72109450 |
| 39 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71083776 |
| 40 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.67794968 |
| 41 | SPI1_23127762_ChIP-Seq_K562_Human | 1.64091316 |
| 42 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.62020281 |
| 43 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.59527694 |
| 44 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.52608981 |
| 45 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.52145527 |
| 46 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.46652425 |
| 47 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.37823098 |
| 48 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.33790212 |
| 49 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.32079146 |
| 50 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.27724074 |
| 51 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.24985113 |
| 52 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.23700696 |
| 53 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22704187 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.20868902 |
| 55 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.19998111 |
| 56 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.19408875 |
| 57 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.19016453 |
| 58 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.18650728 |
| 59 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.18608324 |
| 60 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.15243567 |
| 61 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.13804742 |
| 62 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.13424393 |
| 63 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13034596 |
| 64 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.10562659 |
| 65 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10490862 |
| 66 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.06834366 |
| 67 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.06783621 |
| 68 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04072944 |
| 69 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.00441665 |
| 70 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.99730663 |
| 71 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.98773572 |
| 72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.96533945 |
| 73 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.94257884 |
| 74 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.94237635 |
| 75 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.93345961 |
| 76 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.91492666 |
| 77 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.91225705 |
| 78 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91138521 |
| 79 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88399834 |
| 80 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.87208602 |
| 81 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.86580700 |
| 82 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.86070460 |
| 83 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.84808602 |
| 84 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82058781 |
| 85 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80138626 |
| 86 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.79520265 |
| 87 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.78683878 |
| 88 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.78474317 |
| 89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78369328 |
| 90 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.77886320 |
| 91 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.77625506 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.76828032 |
| 93 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.76633995 |
| 94 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.75961701 |
| 95 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.74960198 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.74614204 |
| 97 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.74545477 |
| 98 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.74492674 |
| 99 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.73306075 |
| 100 | GATA3_26560356_Chip-Seq_TH1_Human | 0.72435366 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 4.82451293 |
| 2 | MP0005671_abnormal_response_to | 4.75880468 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.90130169 |
| 4 | MP0003436_decreased_susceptibility_to | 3.54562292 |
| 5 | MP0001873_stomach_inflammation | 3.30208265 |
| 6 | MP0001800_abnormal_humoral_immune | 3.26952198 |
| 7 | MP0005000_abnormal_immune_tolerance | 3.24209348 |
| 8 | MP0009333_abnormal_splenocyte_physiolog | 3.20514408 |
| 9 | MP0000685_abnormal_immune_system | 3.13081336 |
| 10 | MP0005387_immune_system_phenotype | 3.03895770 |
| 11 | MP0001790_abnormal_immune_system | 3.03895770 |
| 12 | MP0003724_increased_susceptibility_to | 2.89886827 |
| 13 | MP0009785_altered_susceptibility_to | 2.76670989 |
| 14 | MP0005025_abnormal_response_to | 2.74674642 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.74559520 |
| 16 | MP0002723_abnormal_immune_serum | 2.73075855 |
| 17 | MP0001819_abnormal_immune_cell | 2.70258199 |
| 18 | MP0006082_CNS_inflammation | 2.50988415 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.50170622 |
| 20 | MP0003866_abnormal_defecation | 2.50161237 |
| 21 | MP0000703_abnormal_thymus_morphology | 2.43169337 |
| 22 | MP0002398_abnormal_bone_marrow | 2.42741131 |
| 23 | MP0002405_respiratory_system_inflammati | 2.35039894 |
| 24 | MP0010155_abnormal_intestine_physiology | 2.27157259 |
| 25 | MP0000716_abnormal_immune_system | 2.23064478 |
| 26 | MP0002419_abnormal_innate_immunity | 2.22638380 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 2.22461759 |
| 28 | MP0004381_abnormal_hair_follicle | 2.01189223 |
| 29 | MP0001348_abnormal_lacrimal_gland | 2.00492631 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.96205629 |
| 31 | MP0002722_abnormal_immune_system | 1.93421888 |
| 32 | MP0000689_abnormal_spleen_morphology | 1.93420885 |
| 33 | MP0005310_abnormal_salivary_gland | 1.92471009 |
| 34 | MP0003300_gastrointestinal_ulcer | 1.88663357 |
| 35 | MP0003303_peritoneal_inflammation | 1.82992187 |
| 36 | MP0005464_abnormal_platelet_physiology | 1.77584745 |
| 37 | MP0004947_skin_inflammation | 1.76539556 |
| 38 | MP0002429_abnormal_blood_cell | 1.75452416 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.71568338 |
| 40 | MP0000465_gastrointestinal_hemorrhage | 1.64850760 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.64357214 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.56634003 |
| 43 | MP0002163_abnormal_gland_morphology | 1.48943403 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.40849965 |
| 45 | MP0002933_joint_inflammation | 1.40610557 |
| 46 | MP0002396_abnormal_hematopoietic_system | 1.36196062 |
| 47 | MP0002006_tumorigenesis | 1.32387274 |
| 48 | MP0008469_abnormal_protein_level | 1.21625712 |
| 49 | MP0003806_abnormal_nucleotide_metabolis | 1.21508968 |
| 50 | MP0002132_abnormal_respiratory_system | 1.20212516 |
| 51 | MP0001851_eye_inflammation | 1.20148701 |
| 52 | MP0001986_abnormal_taste_sensitivity | 1.09381446 |
| 53 | MP0000490_abnormal_crypts_of | 1.06165342 |
| 54 | MP0005083_abnormal_biliary_tract | 1.02894210 |
| 55 | MP0001853_heart_inflammation | 1.02706366 |
| 56 | MP0001663_abnormal_digestive_system | 1.01559871 |
| 57 | MP0002138_abnormal_hepatobiliary_system | 0.96965584 |
| 58 | MP0005451_abnormal_body_composition | 0.94993217 |
| 59 | MP0000858_altered_metastatic_potential | 0.94752384 |
| 60 | MP0002693_abnormal_pancreas_physiology | 0.89368771 |
| 61 | MP0009764_decreased_sensitivity_to | 0.88483795 |
| 62 | MP0008260_abnormal_autophagy | 0.88370602 |
| 63 | MP0003448_altered_tumor_morphology | 0.87240870 |
| 64 | MP0003191_abnormal_cellular_cholesterol | 0.81836578 |
| 65 | MP0000372_irregular_coat_pigmentation | 0.80424992 |
| 66 | MP0005166_decreased_susceptibility_to | 0.80109416 |
| 67 | MP0002009_preneoplasia | 0.75963417 |
| 68 | MP0003252_abnormal_bile_duct | 0.75443740 |
| 69 | MP0002998_abnormal_bone_remodeling | 0.75426528 |
| 70 | MP0009763_increased_sensitivity_to | 0.74347537 |
| 71 | MP0001346_abnormal_lacrimal_gland | 0.73905091 |
| 72 | MP0005379_endocrine/exocrine_gland_phen | 0.73554458 |
| 73 | MP0002019_abnormal_tumor_incidence | 0.71866843 |
| 74 | MP0000604_amyloidosis | 0.66449337 |
| 75 | MP0008961_abnormal_basal_metabolism | 0.66377440 |
| 76 | MP0004808_abnormal_hematopoietic_stem | 0.63650364 |
| 77 | MP0003878_abnormal_ear_physiology | 0.60370410 |
| 78 | MP0005377_hearing/vestibular/ear_phenot | 0.60370410 |
| 79 | MP0003045_fibrosis | 0.60356637 |
| 80 | MP0008057_abnormal_DNA_replication | 0.57733216 |
| 81 | MP0004883_abnormal_blood_vessel | 0.57141431 |
| 82 | MP0005381_digestive/alimentary_phenotyp | 0.55922176 |
| 83 | MP0005390_skeleton_phenotype | 0.54715808 |
| 84 | MP0004510_myositis | 0.54473106 |
| 85 | MP0003646_muscle_fatigue | 0.53723215 |
| 86 | MP0009278_abnormal_bone_marrow | 0.51608544 |
| 87 | MP0002638_abnormal_pupillary_reflex | 0.51558224 |
| 88 | MP0001764_abnormal_homeostasis | 0.51412767 |
| 89 | MP0000249_abnormal_blood_vessel | 0.50839611 |
| 90 | MP0008004_abnormal_stomach_pH | 0.50554431 |
| 91 | MP0001919_abnormal_reproductive_system | 0.50345189 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.48863464 |
| 93 | MP0004130_abnormal_muscle_cell | 0.48184237 |
| 94 | MP0008872_abnormal_physiological_respon | 0.47808352 |
| 95 | MP0003795_abnormal_bone_structure | 0.47563392 |
| 96 | MP0009765_abnormal_xenobiotic_induced | 0.42891208 |
| 97 | MP0000609_abnormal_liver_physiology | 0.41038784 |
| 98 | MP0003828_pulmonary_edema | 0.40742924 |
| 99 | MP0000920_abnormal_myelination | 0.39828238 |
| 100 | MP0004134_abnormal_chest_morphology | 0.38867871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.55612706 |
| 2 | T lymphocytopenia (HP:0005403) | 6.23960169 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.15805806 |
| 4 | Abnormality of T cell number (HP:0011839) | 6.03633956 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 5.85392045 |
| 6 | Eczematoid dermatitis (HP:0000976) | 5.35797801 |
| 7 | Severe combined immunodeficiency (HP:0004430) | 5.26899923 |
| 8 | Increased IgM level (HP:0003496) | 5.16138593 |
| 9 | Abnormality of T cells (HP:0002843) | 5.13294484 |
| 10 | IgG deficiency (HP:0004315) | 4.76935796 |
| 11 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.50787033 |
| 12 | Combined immunodeficiency (HP:0005387) | 4.27879572 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.26855130 |
| 14 | Myositis (HP:0100614) | 4.24529404 |
| 15 | Abnormality of T cell physiology (HP:0011840) | 4.14257264 |
| 16 | Encephalitis (HP:0002383) | 3.79573318 |
| 17 | IgM deficiency (HP:0002850) | 3.73182395 |
| 18 | Optic neuritis (HP:0100653) | 3.72377768 |
| 19 | Retrobulbar optic neuritis (HP:0100654) | 3.72377768 |
| 20 | Abnormality of eosinophils (HP:0001879) | 3.69066442 |
| 21 | Panhypogammaglobulinemia (HP:0003139) | 3.68688245 |
| 22 | Orchitis (HP:0100796) | 3.59432316 |
| 23 | Eosinophilia (HP:0001880) | 3.56480250 |
| 24 | Abnormality of macrophages (HP:0004311) | 3.55850433 |
| 25 | Meningitis (HP:0001287) | 3.54440429 |
| 26 | Lymphopenia (HP:0001888) | 3.54148347 |
| 27 | Granulocytopenia (HP:0001913) | 3.54029211 |
| 28 | Recurrent abscess formation (HP:0002722) | 3.53044574 |
| 29 | Increased IgE level (HP:0003212) | 3.51917049 |
| 30 | Recurrent bacterial skin infections (HP:0005406) | 3.51358147 |
| 31 | B lymphocytopenia (HP:0010976) | 3.49339857 |
| 32 | Spontaneous hematomas (HP:0007420) | 3.45250206 |
| 33 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.42420976 |
| 34 | Autoimmune thrombocytopenia (HP:0001973) | 3.41379558 |
| 35 | Abnormality of B cell number (HP:0010975) | 3.40229650 |
| 36 | Recurrent cutaneous fungal infections (HP:0011370) | 3.39849501 |
| 37 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.39849501 |
| 38 | Recurrent viral infections (HP:0004429) | 3.38282175 |
| 39 | Chronic obstructive pulmonary disease (HP:0006510) | 3.35757034 |
| 40 | Obstructive lung disease (HP:0006536) | 3.35757034 |
| 41 | Recurrent bronchitis (HP:0002837) | 3.34668496 |
| 42 | Vasculitis (HP:0002633) | 3.34084431 |
| 43 | Leukocytosis (HP:0001974) | 3.32499247 |
| 44 | Mediastinal lymphadenopathy (HP:0100721) | 3.30127355 |
| 45 | Thyroiditis (HP:0100646) | 3.29609793 |
| 46 | Pustule (HP:0200039) | 3.24753955 |
| 47 | Joint swelling (HP:0001386) | 3.18899739 |
| 48 | Pulmonary infiltrates (HP:0002113) | 3.16126207 |
| 49 | Chronic diarrhea (HP:0002028) | 3.15909025 |
| 50 | Hypergammaglobulinemia (HP:0010702) | 3.14298325 |
| 51 | Prolonged bleeding time (HP:0003010) | 3.13793506 |
| 52 | Gastrointestinal infarctions (HP:0005244) | 3.00342372 |
| 53 | Keratoconjunctivitis sicca (HP:0001097) | 2.89909702 |
| 54 | Recurrent skin infections (HP:0001581) | 2.83442758 |
| 55 | Hypochromic anemia (HP:0001931) | 2.82941292 |
| 56 | Petechiae (HP:0000967) | 2.80443382 |
| 57 | Keratoconjunctivitis (HP:0001096) | 2.75559721 |
| 58 | Chest pain (HP:0100749) | 2.70966872 |
| 59 | Epistaxis (HP:0000421) | 2.64907411 |
| 60 | Hypoproteinemia (HP:0003075) | 2.63981494 |
| 61 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.63129520 |
| 62 | Urticaria (HP:0001025) | 2.59200857 |
| 63 | Lymphoma (HP:0002665) | 2.57412090 |
| 64 | Acute hepatic failure (HP:0006554) | 2.52969879 |
| 65 | Hemoptysis (HP:0002105) | 2.52818417 |
| 66 | Purpura (HP:0000979) | 2.51380601 |
| 67 | Aplastic anemia (HP:0001915) | 2.44212576 |
| 68 | Hypochromic microcytic anemia (HP:0004840) | 2.42140374 |
| 69 | Hyperlipoproteinemia (HP:0010980) | 2.33423323 |
| 70 | Pulmonary embolism (HP:0002204) | 2.31421765 |
| 71 | Slow saccadic eye movements (HP:0000514) | 2.30005476 |
| 72 | Microcytic anemia (HP:0001935) | 2.26253323 |
| 73 | Hypoplasia of the thymus (HP:0000778) | 2.22361392 |
| 74 | Bronchitis (HP:0012387) | 2.22184606 |
| 75 | Gingivitis (HP:0000230) | 2.19496690 |
| 76 | Papilledema (HP:0001085) | 2.18711522 |
| 77 | Inflammation of the large intestine (HP:0002037) | 2.17546889 |
| 78 | Agammaglobulinemia (HP:0004432) | 2.17444871 |
| 79 | Arterial thrombosis (HP:0004420) | 2.10278645 |
| 80 | Gastrointestinal inflammation (HP:0004386) | 2.10070559 |
| 81 | Verrucae (HP:0200043) | 2.09360063 |
| 82 | Papilloma (HP:0012740) | 2.09360063 |
| 83 | Gingival bleeding (HP:0000225) | 2.08745353 |
| 84 | Gangrene (HP:0100758) | 2.07235362 |
| 85 | IgA deficiency (HP:0002720) | 2.04258680 |
| 86 | Recurrent sinusitis (HP:0011108) | 2.01031460 |
| 87 | Pancytopenia (HP:0001876) | 2.00296649 |
| 88 | Basal cell carcinoma (HP:0002671) | 2.00275216 |
| 89 | Anorexia (HP:0002039) | 2.00170810 |
| 90 | Chronic otitis media (HP:0000389) | 1.99094965 |
| 91 | Abnormality of the prostate (HP:0008775) | 1.97704857 |
| 92 | Nasal polyposis (HP:0100582) | 1.97692637 |
| 93 | Sepsis (HP:0100806) | 1.94550109 |
| 94 | Recurrent otitis media (HP:0000403) | 1.94158087 |
| 95 | Gastrointestinal stroma tumor (HP:0100723) | 1.92336236 |
| 96 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.89462077 |
| 97 | Abnormality of the pleura (HP:0002103) | 1.87180615 |
| 98 | Abnormal platelet volume (HP:0011876) | 1.85822570 |
| 99 | Episodic fever (HP:0001954) | 1.84574698 |
| 100 | Keratitis (HP:0000491) | 1.84044032 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.62338563 |
| 2 | MAP4K1 | 5.16034600 |
| 3 | ITK | 3.03130279 |
| 4 | RIPK4 | 2.92663983 |
| 5 | ZAP70 | 2.87576942 |
| 6 | FES | 2.80095197 |
| 7 | TESK2 | 2.50034008 |
| 8 | BTK | 2.49715831 |
| 9 | KDR | 2.45955219 |
| 10 | TAOK3 | 2.45589342 |
| 11 | SIK3 | 2.28473483 |
| 12 | NLK | 2.15681067 |
| 13 | CSK | 2.10545769 |
| 14 | TNK2 | 2.07373945 |
| 15 | MARK3 | 1.98876190 |
| 16 | MAP3K11 | 1.97509781 |
| 17 | TYK2 | 1.94805373 |
| 18 | TEC | 1.93761655 |
| 19 | GRK6 | 1.91353625 |
| 20 | PASK | 1.88702307 |
| 21 | LCK | 1.84666757 |
| 22 | IKBKE | 1.82507241 |
| 23 | SYK | 1.80114754 |
| 24 | JAK3 | 1.67626268 |
| 25 | PRPF4B | 1.63423237 |
| 26 | BLK | 1.62112678 |
| 27 | HCK | 1.59023724 |
| 28 | MAP2K3 | 1.39064499 |
| 29 | LYN | 1.33722708 |
| 30 | EPHB1 | 1.32313708 |
| 31 | MAP3K12 | 1.27592556 |
| 32 | IRAK4 | 1.27424628 |
| 33 | JAK1 | 1.25611707 |
| 34 | TAOK1 | 1.20673938 |
| 35 | MAP3K3 | 1.20062075 |
| 36 | CAMKK1 | 1.18011906 |
| 37 | MAP3K14 | 1.17751986 |
| 38 | MST4 | 1.15799643 |
| 39 | SCYL2 | 1.15062936 |
| 40 | SIK2 | 1.14403312 |
| 41 | HIPK2 | 1.12080170 |
| 42 | PRKCQ | 1.10898095 |
| 43 | CAMKK2 | 1.08430107 |
| 44 | SMG1 | 1.05299871 |
| 45 | IKBKB | 1.03721342 |
| 46 | TAOK2 | 0.92348465 |
| 47 | PIM1 | 0.89027525 |
| 48 | CSF1R | 0.88738548 |
| 49 | ERN1 | 0.87090070 |
| 50 | FGFR4 | 0.85636861 |
| 51 | JAK2 | 0.84935751 |
| 52 | SIK1 | 0.77544751 |
| 53 | TBK1 | 0.74576103 |
| 54 | FGR | 0.71332448 |
| 55 | STK10 | 0.67839766 |
| 56 | FGFR3 | 0.66524880 |
| 57 | MAP3K13 | 0.64916207 |
| 58 | TESK1 | 0.61345563 |
| 59 | TLK1 | 0.59712036 |
| 60 | MAP3K1 | 0.59101326 |
| 61 | FYN | 0.57194698 |
| 62 | CLK1 | 0.53559967 |
| 63 | MELK | 0.52728883 |
| 64 | CDK4 | 0.51831459 |
| 65 | PDK1 | 0.51569371 |
| 66 | PIK3CG | 0.47826851 |
| 67 | GRK5 | 0.46419775 |
| 68 | MAP2K6 | 0.44576435 |
| 69 | ADRBK2 | 0.44349556 |
| 70 | LRRK2 | 0.44114709 |
| 71 | TGFBR2 | 0.42797782 |
| 72 | MAP3K7 | 0.42303485 |
| 73 | MAPKAPK2 | 0.42172944 |
| 74 | MAP3K10 | 0.41294804 |
| 75 | NUAK1 | 0.39590404 |
| 76 | MARK2 | 0.38949784 |
| 77 | KIT | 0.38284634 |
| 78 | MAPK11 | 0.36481103 |
| 79 | TYRO3 | 0.35223867 |
| 80 | MAPK12 | 0.33213723 |
| 81 | DAPK1 | 0.32391038 |
| 82 | STK11 | 0.29259270 |
| 83 | GRK7 | 0.27192461 |
| 84 | STK4 | 0.26611322 |
| 85 | BMPR2 | 0.25246934 |
| 86 | MAP3K5 | 0.24689613 |
| 87 | STK16 | 0.24649200 |
| 88 | CDK19 | 0.24529179 |
| 89 | TAF1 | 0.24253449 |
| 90 | NEK6 | 0.23863598 |
| 91 | TRPM7 | 0.23230856 |
| 92 | BCR | 0.21998874 |
| 93 | STK38 | 0.20080544 |
| 94 | YES1 | 0.19966670 |
| 95 | INSR | 0.19743834 |
| 96 | IGF1R | 0.19539603 |
| 97 | IRAK1 | 0.19533112 |
| 98 | PRKCH | 0.17967816 |
| 99 | PDGFRB | 0.17727330 |
| 100 | KSR2 | 0.17521441 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.84694537 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.84641578 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.53044677 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.49291982 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.97017124 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.95906744 |
| 7 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.78423620 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.69979405 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.63372443 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.36818984 |
| 11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.24989195 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.16463770 |
| 13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.11091049 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.02988443 |
| 15 | Leishmaniasis_Homo sapiens_hsa05140 | 1.69385896 |
| 16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.68927599 |
| 17 | Malaria_Homo sapiens_hsa05144 | 1.65876967 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.62270637 |
| 19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.60943829 |
| 20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.58958947 |
| 21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.58323908 |
| 22 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.55073226 |
| 23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.52385597 |
| 24 | Asthma_Homo sapiens_hsa05310 | 1.47247847 |
| 25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.43097137 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.37518084 |
| 27 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.35582610 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.34953180 |
| 29 | Proteasome_Homo sapiens_hsa03050 | 1.34283569 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.31685731 |
| 31 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.24393207 |
| 32 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.17884601 |
| 33 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.17831186 |
| 34 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.17587778 |
| 35 | Shigellosis_Homo sapiens_hsa05131 | 1.15319612 |
| 36 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.14598218 |
| 37 | Hepatitis B_Homo sapiens_hsa05161 | 1.11550446 |
| 38 | Platelet activation_Homo sapiens_hsa04611 | 1.08193136 |
| 39 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.03166345 |
| 40 | Tuberculosis_Homo sapiens_hsa05152 | 1.01508243 |
| 41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.00683838 |
| 42 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.98046669 |
| 43 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.96443563 |
| 44 | Influenza A_Homo sapiens_hsa05164 | 0.93504735 |
| 45 | Apoptosis_Homo sapiens_hsa04210 | 0.91669625 |
| 46 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.90702956 |
| 47 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.90138707 |
| 48 | Legionellosis_Homo sapiens_hsa05134 | 0.89410933 |
| 49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.82718603 |
| 50 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.81271878 |
| 51 | HTLV-I infection_Homo sapiens_hsa05166 | 0.80036605 |
| 52 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79029345 |
| 53 | Ribosome_Homo sapiens_hsa03010 | 0.78500722 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74817690 |
| 55 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71899340 |
| 56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.68619974 |
| 57 | Endocytosis_Homo sapiens_hsa04144 | 0.64516180 |
| 58 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.62126865 |
| 59 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.61047800 |
| 60 | Hepatitis C_Homo sapiens_hsa05160 | 0.60638450 |
| 61 | Salmonella infection_Homo sapiens_hsa05132 | 0.56059364 |
| 62 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.55355646 |
| 63 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.51989244 |
| 64 | Pertussis_Homo sapiens_hsa05133 | 0.47491227 |
| 65 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.46279348 |
| 66 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44166850 |
| 67 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43275836 |
| 68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.41833737 |
| 69 | Phototransduction_Homo sapiens_hsa04744 | 0.41827717 |
| 70 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.37765155 |
| 71 | Endometrial cancer_Homo sapiens_hsa05213 | 0.37534737 |
| 72 | Olfactory transduction_Homo sapiens_hsa04740 | 0.36874524 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.35752091 |
| 74 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35467874 |
| 75 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.35357912 |
| 76 | Phagosome_Homo sapiens_hsa04145 | 0.32386461 |
| 77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.31745483 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.30578263 |
| 79 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.27772998 |
| 80 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.27100915 |
| 81 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.26767589 |
| 82 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.25631351 |
| 83 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.25550657 |
| 84 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22429253 |
| 85 | Morphine addiction_Homo sapiens_hsa05032 | 0.20746629 |
| 86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.20552371 |
| 87 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.20061947 |
| 88 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.19915293 |
| 89 | Prostate cancer_Homo sapiens_hsa05215 | 0.18953536 |
| 90 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.18932539 |
| 91 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.18435514 |
| 92 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.18065027 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.13963956 |
| 94 | Long-term potentiation_Homo sapiens_hsa04720 | 0.13774245 |
| 95 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.13461250 |
| 96 | Insulin resistance_Homo sapiens_hsa04931 | 0.13388606 |
| 97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.12588626 |
| 98 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.12043204 |
| 99 | Pathways in cancer_Homo sapiens_hsa05200 | 0.11797692 |
| 100 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.09799489 |

