

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | thrombin receptor signaling pathway (GO:0070493) | 8.16432697 |
| 2 | protein neddylation (GO:0045116) | 6.76710533 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 6.66656698 |
| 4 | negative regulation of thymocyte apoptotic process (GO:0070244) | 6.25738127 |
| 5 | blood coagulation, intrinsic pathway (GO:0007597) | 5.83128942 |
| 6 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 5.77936376 |
| 7 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.75798677 |
| 8 | regulation of platelet aggregation (GO:0090330) | 5.69197606 |
| 9 | regulation of platelet activation (GO:0010543) | 5.52031218 |
| 10 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 5.19514057 |
| 11 | adenosine receptor signaling pathway (GO:0001973) | 5.02185695 |
| 12 | platelet aggregation (GO:0070527) | 4.90884314 |
| 13 | positive regulation of macrophage differentiation (GO:0045651) | 4.90740490 |
| 14 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.90405082 |
| 15 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 4.82276180 |
| 16 | low-density lipoprotein particle remodeling (GO:0034374) | 4.80538256 |
| 17 | angiogenesis involved in wound healing (GO:0060055) | 4.75803631 |
| 18 | negative regulation of norepinephrine secretion (GO:0010700) | 4.70612829 |
| 19 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.69085856 |
| 20 | negative regulation of heart rate (GO:0010459) | 4.68362374 |
| 21 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.53882566 |
| 22 | negative regulation of platelet activation (GO:0010544) | 4.52514757 |
| 23 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 4.49145785 |
| 24 | lipoxygenase pathway (GO:0019372) | 4.46172927 |
| 25 | positive regulation of mast cell activation (GO:0033005) | 4.31193988 |
| 26 | purinergic receptor signaling pathway (GO:0035587) | 4.30813788 |
| 27 | regulation of transforming growth factor beta2 production (GO:0032909) | 4.25624096 |
| 28 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 4.22977604 |
| 29 | regulation of integrin-mediated signaling pathway (GO:2001044) | 4.19369149 |
| 30 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 4.16711962 |
| 31 | neutrophil activation (GO:0042119) | 4.09059868 |
| 32 | negative regulation of T cell apoptotic process (GO:0070233) | 4.05960892 |
| 33 | mitochondrial calcium ion transport (GO:0006851) | 3.98404839 |
| 34 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.95653834 |
| 35 | regulation of integrin activation (GO:0033623) | 3.78502213 |
| 36 | activated T cell proliferation (GO:0050798) | 3.76660908 |
| 37 | regulation of RIG-I signaling pathway (GO:0039535) | 3.75644975 |
| 38 | platelet activation (GO:0030168) | 3.75540591 |
| 39 | negative regulation of appetite (GO:0032099) | 3.73821955 |
| 40 | negative regulation of response to food (GO:0032096) | 3.73821955 |
| 41 | positive regulation of granulocyte differentiation (GO:0030854) | 3.66708107 |
| 42 | platelet degranulation (GO:0002576) | 3.64779351 |
| 43 | positive regulation of protein homodimerization activity (GO:0090073) | 3.60206595 |
| 44 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.60078412 |
| 45 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.55893063 |
| 46 | regulation of lipoprotein metabolic process (GO:0050746) | 3.54240886 |
| 47 | megakaryocyte development (GO:0035855) | 3.54190146 |
| 48 | granulocyte activation (GO:0036230) | 3.51877632 |
| 49 | platelet formation (GO:0030220) | 3.50697121 |
| 50 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.46357342 |
| 51 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.43350286 |
| 52 | homotypic cell-cell adhesion (GO:0034109) | 3.43243902 |
| 53 | regulation of thymocyte apoptotic process (GO:0070243) | 3.42807226 |
| 54 | beta-amyloid metabolic process (GO:0050435) | 3.40401751 |
| 55 | high-density lipoprotein particle remodeling (GO:0034375) | 3.39877644 |
| 56 | polyamine biosynthetic process (GO:0006596) | 3.37520788 |
| 57 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.37101625 |
| 58 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.36867792 |
| 59 | phospholipid homeostasis (GO:0055091) | 3.33818207 |
| 60 | regulation of cholesterol efflux (GO:0010874) | 3.32978510 |
| 61 | plasma membrane fusion (GO:0045026) | 3.28320790 |
| 62 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.25913473 |
| 63 | negative regulation of protein localization to cell surface (GO:2000009) | 3.24322597 |
| 64 | regulation of norepinephrine secretion (GO:0014061) | 3.22758717 |
| 65 | fibril organization (GO:0097435) | 3.21310404 |
| 66 | reverse cholesterol transport (GO:0043691) | 3.18122871 |
| 67 | positive regulation of T cell cytokine production (GO:0002726) | 3.16639703 |
| 68 | negative regulation of heart contraction (GO:0045822) | 3.16467161 |
| 69 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.15687352 |
| 70 | regulation of endothelial cell differentiation (GO:0045601) | 3.14974239 |
| 71 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.14485694 |
| 72 | negative regulation of stress fiber assembly (GO:0051497) | 3.11269566 |
| 73 | autophagic vacuole fusion (GO:0000046) | 3.11231155 |
| 74 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.10929467 |
| 75 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.10748124 |
| 76 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.10645135 |
| 77 | platelet dense granule organization (GO:0060155) | 3.06803346 |
| 78 | monoamine transport (GO:0015844) | 3.03878327 |
| 79 | cellular response to arsenic-containing substance (GO:0071243) | 3.02777781 |
| 80 | positive regulation of hemostasis (GO:1900048) | 3.02735114 |
| 81 | positive regulation of blood coagulation (GO:0030194) | 3.02735114 |
| 82 | phagocytosis, engulfment (GO:0006911) | 3.01090807 |
| 83 | leukocyte degranulation (GO:0043299) | 2.93640503 |
| 84 | regulation of mast cell activation (GO:0033003) | 2.92383711 |
| 85 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.89450978 |
| 86 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 2.88204934 |
| 87 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.87322301 |
| 88 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.87322301 |
| 89 | positive regulation of transforming growth factor beta production (GO:0071636) | 2.85836048 |
| 90 | protein localization to cell surface (GO:0034394) | 2.83857809 |
| 91 | negative regulation of catecholamine secretion (GO:0033604) | 2.83739282 |
| 92 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 2.82050469 |
| 93 | regulation of memory T cell differentiation (GO:0043380) | 2.81928620 |
| 94 | termination of signal transduction (GO:0023021) | 2.81399899 |
| 95 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.80986860 |
| 96 | extracellular fibril organization (GO:0043206) | 2.79262772 |
| 97 | positive regulation of mast cell degranulation (GO:0043306) | 2.78208823 |
| 98 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.78208823 |
| 99 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.76415818 |
| 100 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.75344614 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 4.80635672 |
| 2 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 4.32160460 |
| 3 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.68714060 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.39582013 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.27873650 |
| 6 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 3.23132100 |
| 7 | GATA1_22025678_ChIP-Seq_K562_Human | 3.11389369 |
| 8 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.95534313 |
| 9 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.95322433 |
| 10 | GATA1_19941826_ChIP-Seq_K562_Human | 2.86933447 |
| 11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.68814371 |
| 12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.66554079 |
| 13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.64413247 |
| 14 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 2.59422205 |
| 15 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.52785932 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.47566462 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.44989346 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.36427567 |
| 19 | GATA2_19941826_ChIP-Seq_K562_Human | 2.32706887 |
| 20 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.23753552 |
| 21 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.14590633 |
| 22 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.13213530 |
| 23 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.11719583 |
| 24 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 2.11021394 |
| 25 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.10875392 |
| 26 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.05035809 |
| 27 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 2.04875525 |
| 28 | SPI1_23127762_ChIP-Seq_K562_Human | 2.04767267 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.97471240 |
| 30 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.95074774 |
| 31 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.93604802 |
| 32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.82093857 |
| 33 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79167072 |
| 34 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.74305491 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.72600389 |
| 36 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.64657406 |
| 37 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.59428142 |
| 38 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.57974184 |
| 39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.56472462 |
| 40 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.55151634 |
| 41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.53515616 |
| 42 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.50020169 |
| 43 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.48907004 |
| 44 | MYB_26560356_Chip-Seq_TH2_Human | 1.39306250 |
| 45 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.37166845 |
| 46 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.35657866 |
| 47 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.34909508 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.34709877 |
| 49 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.30051445 |
| 50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.28112687 |
| 51 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.21676410 |
| 52 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.21163451 |
| 53 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20526509 |
| 54 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.20343677 |
| 55 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.19953159 |
| 56 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.17696094 |
| 57 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.16523951 |
| 58 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15178722 |
| 59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09929373 |
| 60 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.09800741 |
| 61 | MYB_26560356_Chip-Seq_TH1_Human | 1.08398121 |
| 62 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.06716638 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.05950743 |
| 64 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.05950255 |
| 65 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.05747023 |
| 66 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.02009620 |
| 67 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.00209595 |
| 68 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.00048719 |
| 69 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.99408285 |
| 70 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.97426473 |
| 71 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.95915680 |
| 72 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.93550587 |
| 73 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.93550587 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91745047 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.91110341 |
| 76 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90086376 |
| 77 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.87204668 |
| 78 | VDR_22108803_ChIP-Seq_LS180_Human | 0.86637522 |
| 79 | EWS_26573619_Chip-Seq_HEK293_Human | 0.83327180 |
| 80 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.82715065 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.82085144 |
| 82 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.81719008 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 0.81535338 |
| 84 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81102596 |
| 85 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.80902540 |
| 86 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.80751899 |
| 87 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.80553531 |
| 88 | MAF_26560356_Chip-Seq_TH1_Human | 0.80181211 |
| 89 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.78868532 |
| 90 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.78375175 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.77958879 |
| 92 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.76630711 |
| 93 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.76108074 |
| 94 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.75825601 |
| 95 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.75611409 |
| 96 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.72370186 |
| 97 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.71601422 |
| 98 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.70968838 |
| 99 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.70452825 |
| 100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.70375802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 9.33218091 |
| 2 | MP0008004_abnormal_stomach_pH | 4.39009058 |
| 3 | MP0003724_increased_susceptibility_to | 3.41380482 |
| 4 | MP0000465_gastrointestinal_hemorrhage | 3.14596013 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.00774661 |
| 6 | MP0003303_peritoneal_inflammation | 2.52059194 |
| 7 | MP0005671_abnormal_response_to | 2.43032633 |
| 8 | MP0003566_abnormal_cell_adhesion | 2.41468550 |
| 9 | MP0001851_eye_inflammation | 2.28439512 |
| 10 | MP0000343_altered_response_to | 2.22916959 |
| 11 | MP0004510_myositis | 2.18728411 |
| 12 | MP0003763_abnormal_thymus_physiology | 2.05243334 |
| 13 | MP0000230_abnormal_systemic_arterial | 2.02763057 |
| 14 | MP0010155_abnormal_intestine_physiology | 2.00368788 |
| 15 | MP0004130_abnormal_muscle_cell | 1.97165615 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 1.92201627 |
| 17 | MP0002398_abnormal_bone_marrow | 1.84917356 |
| 18 | MP0001879_abnormal_lymphatic_vessel | 1.84301087 |
| 19 | MP0002736_abnormal_nociception_after | 1.79169133 |
| 20 | MP0005000_abnormal_immune_tolerance | 1.77300653 |
| 21 | MP0005083_abnormal_biliary_tract | 1.74645751 |
| 22 | MP0000858_altered_metastatic_potential | 1.70174923 |
| 23 | MP0008775_abnormal_heart_ventricle | 1.62495870 |
| 24 | MP0004084_abnormal_cardiac_muscle | 1.60139459 |
| 25 | MP0002723_abnormal_immune_serum | 1.59999495 |
| 26 | MP0003638_abnormal_response/metabolism_ | 1.58990543 |
| 27 | MP0005084_abnormal_gallbladder_morpholo | 1.51061996 |
| 28 | MP0005410_abnormal_fertilization | 1.50201694 |
| 29 | MP0001800_abnormal_humoral_immune | 1.49937618 |
| 30 | MP0003828_pulmonary_edema | 1.48042217 |
| 31 | MP0005646_abnormal_pituitary_gland | 1.42145020 |
| 32 | MP0008872_abnormal_physiological_respon | 1.41749065 |
| 33 | MP0003436_decreased_susceptibility_to | 1.39422284 |
| 34 | MP0009763_increased_sensitivity_to | 1.37286638 |
| 35 | MP0003879_abnormal_hair_cell | 1.35817237 |
| 36 | MP0002420_abnormal_adaptive_immunity | 1.35381593 |
| 37 | MP0001819_abnormal_immune_cell | 1.31705271 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.31606068 |
| 39 | MP0004134_abnormal_chest_morphology | 1.31570824 |
| 40 | MP0002452_abnormal_antigen_presenting | 1.29228128 |
| 41 | MP0002132_abnormal_respiratory_system | 1.28831606 |
| 42 | MP0002429_abnormal_blood_cell | 1.28365589 |
| 43 | MP0009785_altered_susceptibility_to | 1.27109981 |
| 44 | MP0009765_abnormal_xenobiotic_induced | 1.27088453 |
| 45 | MP0001663_abnormal_digestive_system | 1.26974775 |
| 46 | MP0005025_abnormal_response_to | 1.26728388 |
| 47 | MP0010329_abnormal_lipoprotein_level | 1.24566553 |
| 48 | MP0001533_abnormal_skeleton_physiology | 1.24290106 |
| 49 | MP0004947_skin_inflammation | 1.24129996 |
| 50 | MP0001968_abnormal_touch/_nociception | 1.24098132 |
| 51 | MP0002722_abnormal_immune_system | 1.23978574 |
| 52 | MP0009764_decreased_sensitivity_to | 1.23850137 |
| 53 | MP0000716_abnormal_immune_system | 1.22395153 |
| 54 | MP0005167_abnormal_blood-brain_barrier | 1.21067842 |
| 55 | MP0009333_abnormal_splenocyte_physiolog | 1.20544576 |
| 56 | MP0000249_abnormal_blood_vessel | 1.19569071 |
| 57 | MP0002733_abnormal_thermal_nociception | 1.17914858 |
| 58 | MP0004036_abnormal_muscle_relaxation | 1.17450159 |
| 59 | MP0005058_abnormal_lysosome_morphology | 1.16715918 |
| 60 | MP0003866_abnormal_defecation | 1.14435313 |
| 61 | MP0001845_abnormal_inflammatory_respons | 1.12765971 |
| 62 | MP0002638_abnormal_pupillary_reflex | 1.11640214 |
| 63 | MP0000685_abnormal_immune_system | 1.09703778 |
| 64 | MP0000703_abnormal_thymus_morphology | 1.05664805 |
| 65 | MP0001545_abnormal_hematopoietic_system | 1.03633760 |
| 66 | MP0005397_hematopoietic_system_phenotyp | 1.03633760 |
| 67 | MP0005387_immune_system_phenotype | 1.02032416 |
| 68 | MP0001790_abnormal_immune_system | 1.02032416 |
| 69 | MP0002419_abnormal_innate_immunity | 0.98565613 |
| 70 | MP0009642_abnormal_blood_homeostasis | 0.98463861 |
| 71 | MP0008874_decreased_physiological_sensi | 0.97133559 |
| 72 | MP0001765_abnormal_ion_homeostasis | 0.96209439 |
| 73 | MP0009697_abnormal_copulation | 0.88409784 |
| 74 | MP0005666_abnormal_adipose_tissue | 0.88379844 |
| 75 | MP0008569_lethality_at_weaning | 0.85609811 |
| 76 | MP0001970_abnormal_pain_threshold | 0.84994866 |
| 77 | MP0004215_abnormal_myocardial_fiber | 0.84307614 |
| 78 | MP0003656_abnormal_erythrocyte_physiolo | 0.84058496 |
| 79 | MP0000015_abnormal_ear_pigmentation | 0.83413089 |
| 80 | MP0000383_abnormal_hair_follicle | 0.83250870 |
| 81 | MP0004484_altered_response_of | 0.81445212 |
| 82 | MP0002653_abnormal_ependyma_morphology | 0.80742419 |
| 83 | MP0005381_digestive/alimentary_phenotyp | 0.77041469 |
| 84 | MP0010386_abnormal_urinary_bladder | 0.75503035 |
| 85 | MP0000490_abnormal_crypts_of | 0.74220387 |
| 86 | MP0004381_abnormal_hair_follicle | 0.72253236 |
| 87 | MP0003300_gastrointestinal_ulcer | 0.69842620 |
| 88 | MP0005174_abnormal_tail_pigmentation | 0.69274743 |
| 89 | MP0002118_abnormal_lipid_homeostasis | 0.68191304 |
| 90 | MP0002128_abnormal_blood_circulation | 0.67029832 |
| 91 | MP0005165_increased_susceptibility_to | 0.66624884 |
| 92 | MP0003011_delayed_dark_adaptation | 0.66555826 |
| 93 | MP0005385_cardiovascular_system_phenoty | 0.65873681 |
| 94 | MP0001544_abnormal_cardiovascular_syste | 0.65873681 |
| 95 | MP0005535_abnormal_body_temperature | 0.65583444 |
| 96 | MP0002405_respiratory_system_inflammati | 0.65258614 |
| 97 | MP0005409_darkened_coat_color | 0.64012636 |
| 98 | MP0004808_abnormal_hematopoietic_stem | 0.63832715 |
| 99 | MP0002998_abnormal_bone_remodeling | 0.62362879 |
| 100 | MP0006036_abnormal_mitochondrial_physio | 0.60108567 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal platelet volume (HP:0011876) | 9.84537260 |
| 2 | Petechiae (HP:0000967) | 9.51063795 |
| 3 | Purpura (HP:0000979) | 8.92302388 |
| 4 | Epistaxis (HP:0000421) | 7.70063869 |
| 5 | Gingival bleeding (HP:0000225) | 6.64816454 |
| 6 | Hyperlipoproteinemia (HP:0010980) | 6.47677445 |
| 7 | Abnormal platelet function (HP:0011869) | 5.41394311 |
| 8 | Impaired platelet aggregation (HP:0003540) | 5.41394311 |
| 9 | Spontaneous hematomas (HP:0007420) | 4.24695875 |
| 10 | Poikilocytosis (HP:0004447) | 3.87882937 |
| 11 | Dyschromatopsia (HP:0007641) | 3.66868768 |
| 12 | Conjunctival telangiectasia (HP:0000524) | 3.63314323 |
| 13 | Acanthocytosis (HP:0001927) | 3.52253527 |
| 14 | Abnormality of the common coagulation pathway (HP:0010990) | 3.39811776 |
| 15 | Abnormal pupillary function (HP:0007686) | 3.36430054 |
| 16 | Increased IgM level (HP:0003496) | 3.30561388 |
| 17 | Paralysis (HP:0003470) | 3.29679967 |
| 18 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.21639562 |
| 19 | Bruising susceptibility (HP:0000978) | 3.17916107 |
| 20 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 3.07530612 |
| 21 | Joint swelling (HP:0001386) | 3.00317922 |
| 22 | Abnormality of lateral ventricle (HP:0030047) | 2.84294821 |
| 23 | Stomatitis (HP:0010280) | 2.74198381 |
| 24 | Hepatosplenomegaly (HP:0001433) | 2.46652492 |
| 25 | Decreased central vision (HP:0007663) | 2.43287751 |
| 26 | Arterial thrombosis (HP:0004420) | 2.43129993 |
| 27 | Male infertility (HP:0003251) | 2.36617700 |
| 28 | Xanthomatosis (HP:0000991) | 2.33203091 |
| 29 | Autoimmune hemolytic anemia (HP:0001890) | 2.20973653 |
| 30 | Encephalitis (HP:0002383) | 2.18698047 |
| 31 | Upper limb muscle weakness (HP:0003484) | 2.16412335 |
| 32 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.13678878 |
| 33 | Papillary thyroid carcinoma (HP:0002895) | 2.13001933 |
| 34 | Abnormal auditory evoked potentials (HP:0006958) | 2.12204111 |
| 35 | Abnormality of macrophages (HP:0004311) | 2.09639009 |
| 36 | 3-Methylglutaconic aciduria (HP:0003535) | 2.08634600 |
| 37 | Increased density of long bones (HP:0006392) | 2.08471028 |
| 38 | Prolonged bleeding time (HP:0003010) | 11.6725947 |
| 39 | Menorrhagia (HP:0000132) | 10.5932783 |
| 40 | Increased mean platelet volume (HP:0011877) | 10.4371992 |
| 41 | Spontaneous abortion (HP:0005268) | 1.99383176 |
| 42 | Episodic fever (HP:0001954) | 1.98805748 |
| 43 | Abnormality of iron homeostasis (HP:0011031) | 1.96880204 |
| 44 | Tinnitus (HP:0000360) | 1.96528962 |
| 45 | Joint hemorrhage (HP:0005261) | 1.94295423 |
| 46 | Abnormal ciliary motility (HP:0012262) | 1.89906216 |
| 47 | Hypoproteinemia (HP:0003075) | 1.89743758 |
| 48 | Vertigo (HP:0002321) | 1.85725606 |
| 49 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.78243081 |
| 50 | Granulocytopenia (HP:0001913) | 1.73514800 |
| 51 | Thyroid-stimulating hormone excess (HP:0002925) | 1.72978637 |
| 52 | IgG deficiency (HP:0004315) | 1.68227958 |
| 53 | Retrobulbar optic neuritis (HP:0100654) | 1.67757131 |
| 54 | Optic neuritis (HP:0100653) | 1.67757131 |
| 55 | Increased serum ferritin (HP:0003281) | 1.67403752 |
| 56 | Arthropathy (HP:0003040) | 1.66255537 |
| 57 | Ventricular fibrillation (HP:0001663) | 1.64791172 |
| 58 | Thrombophlebitis (HP:0004418) | 1.60682315 |
| 59 | Supernumerary ribs (HP:0005815) | 1.59769478 |
| 60 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.59760812 |
| 61 | Vasculitis (HP:0002633) | 1.57510325 |
| 62 | Hypophosphatemic rickets (HP:0004912) | 1.57445878 |
| 63 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.56599779 |
| 64 | Absent/shortened dynein arms (HP:0200106) | 1.56599779 |
| 65 | Infertility (HP:0000789) | 1.56407143 |
| 66 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.56045313 |
| 67 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.56045313 |
| 68 | Dysautonomia (HP:0002459) | 1.55712674 |
| 69 | Basal ganglia calcification (HP:0002135) | 1.54905028 |
| 70 | Thrombocytosis (HP:0001894) | 1.53856702 |
| 71 | Chronic obstructive pulmonary disease (HP:0006510) | 1.53113240 |
| 72 | Obstructive lung disease (HP:0006536) | 1.53113240 |
| 73 | Abnormality of the prostate (HP:0008775) | 1.52906268 |
| 74 | Pulmonary embolism (HP:0002204) | 1.50968700 |
| 75 | Aortic aneurysm (HP:0004942) | 1.50068333 |
| 76 | Cerebral ischemia (HP:0002637) | 1.49241506 |
| 77 | Hyperthyroidism (HP:0000836) | 1.48692979 |
| 78 | Enlarged epiphyses (HP:0010580) | 1.46941746 |
| 79 | Renal Fanconi syndrome (HP:0001994) | 1.45987980 |
| 80 | Nausea (HP:0002018) | 1.45897471 |
| 81 | Generalized aminoaciduria (HP:0002909) | 1.45795203 |
| 82 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.45712392 |
| 83 | Eosinophilia (HP:0001880) | 1.44659270 |
| 84 | Congenital sensorineural hearing impairment (HP:0008527) | 1.43347607 |
| 85 | Abnormal spermatogenesis (HP:0008669) | 1.42150275 |
| 86 | T lymphocytopenia (HP:0005403) | 1.41518084 |
| 87 | Panhypogammaglobulinemia (HP:0003139) | 1.40834132 |
| 88 | Leukocytosis (HP:0001974) | 1.39433981 |
| 89 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.39387386 |
| 90 | Thyroid carcinoma (HP:0002890) | 1.39137524 |
| 91 | Chest pain (HP:0100749) | 1.39044276 |
| 92 | Febrile seizures (HP:0002373) | 1.38470064 |
| 93 | Distal lower limb amyotrophy (HP:0008944) | 1.38322526 |
| 94 | Intellectual disability, profound (HP:0002187) | 1.38107830 |
| 95 | Eczematoid dermatitis (HP:0000976) | 1.38066278 |
| 96 | Abnormality of T cell number (HP:0011839) | 1.37252362 |
| 97 | Metaphyseal dysplasia (HP:0100255) | 1.36611116 |
| 98 | Orchitis (HP:0100796) | 1.35485916 |
| 99 | Myositis (HP:0100614) | 1.34839889 |
| 100 | Abnormality of binocular vision (HP:0011514) | 1.32507537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 4.31096590 |
| 2 | MAP4K2 | 4.17887614 |
| 3 | RIPK4 | 4.15645205 |
| 4 | BMX | 3.65686179 |
| 5 | TAOK3 | 3.15295758 |
| 6 | VRK1 | 3.13733667 |
| 7 | BTK | 3.01453398 |
| 8 | MYLK | 2.92537678 |
| 9 | RIPK1 | 2.89006025 |
| 10 | FES | 2.54969097 |
| 11 | TEC | 2.49017189 |
| 12 | PTK2B | 2.11115442 |
| 13 | TNIK | 1.99589412 |
| 14 | SYK | 1.96706876 |
| 15 | ZAP70 | 1.80657675 |
| 16 | BMPR2 | 1.77460984 |
| 17 | ILK | 1.77288801 |
| 18 | CDK8 | 1.74305048 |
| 19 | EIF2AK1 | 1.74207722 |
| 20 | HCK | 1.72392555 |
| 21 | TLK1 | 1.64895406 |
| 22 | CSF1R | 1.62901225 |
| 23 | GRK5 | 1.61907744 |
| 24 | ZAK | 1.53345330 |
| 25 | GRK6 | 1.48189247 |
| 26 | PIK3CG | 1.46323437 |
| 27 | TYRO3 | 1.43144655 |
| 28 | IRAK3 | 1.36787349 |
| 29 | PRPF4B | 1.33274619 |
| 30 | ADRBK2 | 1.30007834 |
| 31 | ACVR1B | 1.28757677 |
| 32 | TRIM28 | 1.28248284 |
| 33 | LYN | 1.17516998 |
| 34 | TXK | 1.17411981 |
| 35 | STK3 | 1.08436107 |
| 36 | SIK3 | 1.08314080 |
| 37 | RET | 1.02557300 |
| 38 | FGR | 1.00139514 |
| 39 | ITK | 0.99948207 |
| 40 | DAPK3 | 0.99585791 |
| 41 | PDGFRB | 0.98538569 |
| 42 | IKBKB | 0.98440590 |
| 43 | CSK | 0.96289855 |
| 44 | PIK3CA | 0.94060755 |
| 45 | PLK3 | 0.92924108 |
| 46 | MAPKAPK3 | 0.91104896 |
| 47 | TNK2 | 0.90169462 |
| 48 | NLK | 0.90112292 |
| 49 | MAP3K5 | 0.89208750 |
| 50 | LMTK2 | 0.86358576 |
| 51 | PAK1 | 0.82026918 |
| 52 | MAP2K3 | 0.79273350 |
| 53 | BLK | 0.77521490 |
| 54 | JAK1 | 0.74695378 |
| 55 | TRPM7 | 0.72062712 |
| 56 | PDK1 | 0.71158448 |
| 57 | LCK | 0.70261390 |
| 58 | IRAK1 | 0.69034582 |
| 59 | NUAK1 | 0.68963578 |
| 60 | ADRBK1 | 0.66355364 |
| 61 | PIM1 | 0.61106250 |
| 62 | MATK | 0.60654783 |
| 63 | PRKCQ | 0.59866225 |
| 64 | PKN2 | 0.58808752 |
| 65 | PDPK1 | 0.58709486 |
| 66 | BMPR1B | 0.57786118 |
| 67 | PLK2 | 0.56208742 |
| 68 | PIM2 | 0.55750918 |
| 69 | STK4 | 0.54368593 |
| 70 | PRKACG | 0.53842583 |
| 71 | MAP2K6 | 0.53458693 |
| 72 | PKN1 | 0.53193818 |
| 73 | PRKD1 | 0.53162619 |
| 74 | MARK3 | 0.52102920 |
| 75 | MAPK12 | 0.50514274 |
| 76 | PNCK | 0.48120932 |
| 77 | MAP4K1 | 0.45197678 |
| 78 | JAK3 | 0.44747588 |
| 79 | EPHA3 | 0.44225622 |
| 80 | DAPK2 | 0.42908424 |
| 81 | JAK2 | 0.41943601 |
| 82 | PRKCE | 0.41696082 |
| 83 | PRKG1 | 0.40177163 |
| 84 | MELK | 0.40151120 |
| 85 | HIPK2 | 0.39965305 |
| 86 | PHKG1 | 0.39512151 |
| 87 | PHKG2 | 0.39512151 |
| 88 | ERBB2 | 0.38024681 |
| 89 | EPHB2 | 0.37036496 |
| 90 | STK24 | 0.35863627 |
| 91 | LRRK2 | 0.35803284 |
| 92 | FYN | 0.35581199 |
| 93 | TAOK2 | 0.35222713 |
| 94 | IGF1R | 0.33201881 |
| 95 | DYRK1A | 0.31691110 |
| 96 | MAP3K3 | 0.30954754 |
| 97 | ABL2 | 0.29167466 |
| 98 | MAPK13 | 0.27463884 |
| 99 | DAPK1 | 0.26865315 |
| 100 | PRKCB | 0.26370361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.54557752 |
| 2 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 3.56576454 |
| 3 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.72822536 |
| 4 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.52939085 |
| 5 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.95231576 |
| 6 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.91589634 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.86418252 |
| 8 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.85370044 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 1.84215470 |
| 10 | Alcoholism_Homo sapiens_hsa05034 | 1.83569108 |
| 11 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.80892527 |
| 12 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.77476054 |
| 13 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.75886491 |
| 14 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.68854326 |
| 15 | Gap junction_Homo sapiens_hsa04540 | 1.62275737 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.60532279 |
| 17 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.59068587 |
| 18 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.58466982 |
| 19 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.50679081 |
| 20 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.40909173 |
| 21 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.39027719 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.27747264 |
| 23 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.23042767 |
| 24 | Shigellosis_Homo sapiens_hsa05131 | 1.22837133 |
| 25 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.20459294 |
| 26 | Malaria_Homo sapiens_hsa05144 | 1.18963764 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.18432965 |
| 28 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.15345587 |
| 29 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.10969981 |
| 30 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.08998803 |
| 31 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.08113537 |
| 32 | Endocytosis_Homo sapiens_hsa04144 | 1.04879110 |
| 33 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.00791669 |
| 34 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.99778317 |
| 35 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.96291237 |
| 36 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.94372332 |
| 37 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.94180289 |
| 38 | Olfactory transduction_Homo sapiens_hsa04740 | 0.87975704 |
| 39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.87206148 |
| 40 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.86563196 |
| 41 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.84234591 |
| 42 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.83330819 |
| 43 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80878182 |
| 44 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.80210307 |
| 45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.80070703 |
| 46 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.78522390 |
| 47 | Measles_Homo sapiens_hsa05162 | 0.78201376 |
| 48 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.75748938 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.75272616 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.75088752 |
| 51 | Circadian entrainment_Homo sapiens_hsa04713 | 0.71667070 |
| 52 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.70670700 |
| 53 | Endometrial cancer_Homo sapiens_hsa05213 | 0.70350411 |
| 54 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70347215 |
| 55 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.69256987 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.68483985 |
| 57 | Long-term depression_Homo sapiens_hsa04730 | 0.67910319 |
| 58 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.67843126 |
| 59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.66316834 |
| 60 | Morphine addiction_Homo sapiens_hsa05032 | 0.65251815 |
| 61 | Hepatitis B_Homo sapiens_hsa05161 | 0.63204114 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62743057 |
| 63 | Asthma_Homo sapiens_hsa05310 | 0.62210859 |
| 64 | Allograft rejection_Homo sapiens_hsa05330 | 0.61902141 |
| 65 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.61151707 |
| 66 | Focal adhesion_Homo sapiens_hsa04510 | 0.60700491 |
| 67 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.59693669 |
| 68 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.59275273 |
| 69 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.59109385 |
| 70 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.58171432 |
| 71 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.58097421 |
| 72 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.57369938 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.56726357 |
| 74 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.55621860 |
| 75 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.55461920 |
| 76 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.54910918 |
| 77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53403393 |
| 78 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.52589540 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50154954 |
| 80 | Thyroid cancer_Homo sapiens_hsa05216 | 0.49764920 |
| 81 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.49210974 |
| 82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.48971912 |
| 83 | Apoptosis_Homo sapiens_hsa04210 | 0.48898740 |
| 84 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48360060 |
| 85 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.47477424 |
| 86 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.45728417 |
| 87 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44438970 |
| 88 | Phagosome_Homo sapiens_hsa04145 | 0.43803156 |
| 89 | Renin secretion_Homo sapiens_hsa04924 | 0.41475904 |
| 90 | Melanoma_Homo sapiens_hsa05218 | 0.41321923 |
| 91 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.41307159 |
| 92 | Glioma_Homo sapiens_hsa05214 | 0.40031267 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.39519135 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37483728 |
| 95 | Salivary secretion_Homo sapiens_hsa04970 | 0.36540297 |
| 96 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.36399153 |
| 97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35967195 |
| 98 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.34194956 |
| 99 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.32623870 |
| 100 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.32409569 |

