| 1 | modulation by symbiont of host defense response (GO:0052031) | 6.07516797 |
| 2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.07516797 |
| 3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.07516797 |
| 4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.07516797 |
| 5 | modulation by symbiont of host immune response (GO:0052553) | 6.07516797 |
| 6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.07516797 |
| 7 | positive regulation of chemokine biosynthetic process (GO:0045080) | 5.52837336 |
| 8 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.11774065 |
| 9 | negative regulation of cell killing (GO:0031342) | 5.11774065 |
| 10 | detection of other organism (GO:0098543) | 4.84889137 |
| 11 | response to peptidoglycan (GO:0032494) | 4.83347373 |
| 12 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.68429489 |
| 13 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.44398970 |
| 14 | neutrophil activation involved in immune response (GO:0002283) | 4.39288959 |
| 15 | respiratory burst (GO:0045730) | 4.29187922 |
| 16 | regulation of chemokine biosynthetic process (GO:0045073) | 4.22633496 |
| 17 | response to host immune response (GO:0052572) | 4.21993718 |
| 18 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.21993718 |
| 19 | low-density lipoprotein particle clearance (GO:0034383) | 4.14408617 |
| 20 | macrophage activation involved in immune response (GO:0002281) | 4.13278329 |
| 21 | leukocyte aggregation (GO:0070486) | 4.10779654 |
| 22 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 4.10108841 |
| 23 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.03516618 |
| 24 | regulation of gamma-delta T cell activation (GO:0046643) | 3.97563302 |
| 25 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.93700162 |
| 26 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.91547545 |
| 27 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.91547545 |
| 28 | cellular extravasation (GO:0045123) | 3.88378734 |
| 29 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.88320409 |
| 30 | immunoglobulin mediated immune response (GO:0016064) | 3.88286001 |
| 31 | T-helper 1 type immune response (GO:0042088) | 3.87074019 |
| 32 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.85406890 |
| 33 | response to host (GO:0075136) | 3.85406890 |
| 34 | response to host defenses (GO:0052200) | 3.85406890 |
| 35 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.83723302 |
| 36 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.77517171 |
| 37 | positive regulation of humoral immune response (GO:0002922) | 3.74600671 |
| 38 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.72395606 |
| 39 | positive regulation of interferon-alpha production (GO:0032727) | 3.72164172 |
| 40 | germinal center formation (GO:0002467) | 3.69934808 |
| 41 | regulation of interferon-alpha production (GO:0032647) | 3.69152939 |
| 42 | negative regulation of interleukin-12 production (GO:0032695) | 3.67992232 |
| 43 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.61121180 |
| 44 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.60703639 |
| 45 | microglial cell activation (GO:0001774) | 3.57073923 |
| 46 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.56480450 |
| 47 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.56264820 |
| 48 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.55842711 |
| 49 | myeloid leukocyte mediated immunity (GO:0002444) | 3.53777967 |
| 50 | positive regulation of antigen processing and presentation (GO:0002579) | 3.51685133 |
| 51 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 3.47369522 |
| 52 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.44544083 |
| 53 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.44470850 |
| 54 | defense response to protozoan (GO:0042832) | 3.44248549 |
| 55 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.43688882 |
| 56 | reactive oxygen species biosynthetic process (GO:1903409) | 3.40756348 |
| 57 | granulocyte activation (GO:0036230) | 3.38793164 |
| 58 | neutrophil activation (GO:0042119) | 3.36864682 |
| 59 | regulation of podosome assembly (GO:0071801) | 3.34947834 |
| 60 | negative regulation of T cell mediated immunity (GO:0002710) | 3.34611762 |
| 61 | plasma lipoprotein particle clearance (GO:0034381) | 3.33312763 |
| 62 | detection of molecule of bacterial origin (GO:0032490) | 3.29923558 |
| 63 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.27621904 |
| 64 | neutrophil chemotaxis (GO:0030593) | 3.23498402 |
| 65 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.22302471 |
| 66 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.21884529 |
| 67 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.21884529 |
| 68 | response to interleukin-15 (GO:0070672) | 3.21041536 |
| 69 | negative regulation of mast cell activation (GO:0033004) | 3.20200155 |
| 70 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.18626015 |
| 71 | regulation of mast cell degranulation (GO:0043304) | 3.17233202 |
| 72 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.15432930 |
| 73 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.15432930 |
| 74 | neutrophil migration (GO:1990266) | 3.15073219 |
| 75 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.15024146 |
| 76 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.15024146 |
| 77 | regulation of growth of symbiont in host (GO:0044126) | 3.15024146 |
| 78 | negative regulation of growth of symbiont in host (GO:0044130) | 3.15024146 |
| 79 | response to muramyl dipeptide (GO:0032495) | 3.13530312 |
| 80 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.11354987 |
| 81 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.11043984 |
| 82 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.09837928 |
| 83 | response to protozoan (GO:0001562) | 3.09199282 |
| 84 | killing of cells of other organism (GO:0031640) | 3.07502704 |
| 85 | disruption of cells of other organism (GO:0044364) | 3.07502704 |
| 86 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.07287905 |
| 87 | positive regulation of mast cell degranulation (GO:0043306) | 3.07287905 |
| 88 | cellular response to type I interferon (GO:0071357) | 3.06594236 |
| 89 | type I interferon signaling pathway (GO:0060337) | 3.06594236 |
| 90 | neutrophil mediated immunity (GO:0002446) | 3.05498421 |
| 91 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.04759561 |
| 92 | response to type I interferon (GO:0034340) | 3.03963026 |
| 93 | myeloid leukocyte activation (GO:0002274) | 3.03554730 |
| 94 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.02763077 |
| 95 | macrophage activation (GO:0042116) | 3.02504225 |
| 96 | negative regulation of interleukin-17 production (GO:0032700) | 3.02371004 |
| 97 | positive regulation of mast cell activation (GO:0033005) | 3.02214580 |
| 98 | regulation of fever generation (GO:0031620) | 3.01900712 |
| 99 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.01892266 |
| 100 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.00532822 |
| 101 | negative regulation of interleukin-6 production (GO:0032715) | 3.00342969 |
| 102 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.99306620 |
| 103 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.98574702 |
| 104 | superoxide anion generation (GO:0042554) | 2.98038098 |
| 105 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.97739235 |
| 106 | regulation of cytokine secretion involved in immune response (GO:0002739) | 2.97528156 |
| 107 | positive regulation of heat generation (GO:0031652) | 2.96801993 |
| 108 | regulation of macrophage cytokine production (GO:0010935) | 2.96120889 |
| 109 | regulation of antigen processing and presentation (GO:0002577) | 2.96004849 |
| 110 | regulation of leukocyte degranulation (GO:0043300) | 2.93017096 |
| 111 | NIK/NF-kappaB signaling (GO:0038061) | 2.92451404 |
| 112 | leukocyte degranulation (GO:0043299) | 2.91892543 |
| 113 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.91739038 |
| 114 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.91324301 |
| 115 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.90477057 |
| 116 | B cell mediated immunity (GO:0019724) | 2.89821838 |
| 117 | detection of external biotic stimulus (GO:0098581) | 2.88926229 |
| 118 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.88481700 |
| 119 | positive regulation of interferon-beta production (GO:0032728) | 2.88121446 |
| 120 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.87585636 |
| 121 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.85441779 |
| 122 | protein carboxylation (GO:0018214) | 2.85441779 |
| 123 | complement activation, alternative pathway (GO:0006957) | 2.84225284 |
| 124 | leukocyte mediated cytotoxicity (GO:0001909) | 2.82655586 |
| 125 | positive regulation of macrophage cytokine production (GO:0060907) | 2.82245693 |
| 126 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.81404557 |
| 127 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.81169749 |
| 128 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.80628407 |
| 129 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.79980313 |
| 130 | cellular response to interleukin-15 (GO:0071350) | 2.79720085 |
| 131 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.79301210 |
| 132 | positive regulation of cytokine biosynthetic process (GO:0042108) | 2.78595102 |
| 133 | regulation of mast cell activation (GO:0033003) | 2.77633803 |
| 134 | negative regulation of lipid storage (GO:0010888) | 2.76086745 |
| 135 | myeloid cell activation involved in immune response (GO:0002275) | 2.75598287 |
| 136 | urea metabolic process (GO:0019627) | 2.75027139 |
| 137 | urea cycle (GO:0000050) | 2.75027139 |
| 138 | detection of bacterium (GO:0016045) | 2.74727832 |
| 139 | regulation of chronic inflammatory response (GO:0002676) | 2.74025768 |
| 140 | cytokine secretion (GO:0050663) | 2.70704400 |
| 141 | acute-phase response (GO:0006953) | 2.70319927 |
| 142 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.69685771 |
| 143 | detection of biotic stimulus (GO:0009595) | 2.69307884 |
| 144 | I-kappaB phosphorylation (GO:0007252) | 2.68927059 |
TREML4 
