

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.30356185 |
| 2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.28117692 |
| 3 | cytidine metabolic process (GO:0046087) | 6.20248928 |
| 4 | cytidine catabolic process (GO:0006216) | 6.20248928 |
| 5 | cytidine deamination (GO:0009972) | 6.20248928 |
| 6 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.18155895 |
| 7 | negative regulation of cell killing (GO:0031342) | 6.18155895 |
| 8 | cellular response to interleukin-15 (GO:0071350) | 5.95730680 |
| 9 | response to interleukin-15 (GO:0070672) | 5.67641194 |
| 10 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.64920427 |
| 11 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.63174387 |
| 12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.56775795 |
| 13 | negative T cell selection (GO:0043383) | 5.48368877 |
| 14 | positive thymic T cell selection (GO:0045059) | 5.43252121 |
| 15 | DNA deamination (GO:0045006) | 5.35722507 |
| 16 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 5.35325669 |
| 17 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 5.30550101 |
| 18 | regulation of natural killer cell mediated immunity (GO:0002715) | 5.30550101 |
| 19 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.25273747 |
| 20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.24418133 |
| 21 | positive T cell selection (GO:0043368) | 5.21274969 |
| 22 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 5.09575320 |
| 23 | negative thymic T cell selection (GO:0045060) | 5.07772759 |
| 24 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.98628502 |
| 25 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.85518057 |
| 26 | activated T cell proliferation (GO:0050798) | 4.82490349 |
| 27 | regulation of gamma-delta T cell activation (GO:0046643) | 4.76830505 |
| 28 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.69207557 |
| 29 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.63095545 |
| 30 | thymic T cell selection (GO:0045061) | 4.48163462 |
| 31 | T cell migration (GO:0072678) | 4.46994444 |
| 32 | regulation of regulatory T cell differentiation (GO:0045589) | 4.46393001 |
| 33 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.45911490 |
| 34 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 4.35748940 |
| 35 | positive regulation of cell killing (GO:0031343) | 4.35603997 |
| 36 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.28662745 |
| 37 | T cell selection (GO:0045058) | 4.27415029 |
| 38 | regulation of cell killing (GO:0031341) | 4.23353599 |
| 39 | regulation of T cell tolerance induction (GO:0002664) | 4.20313854 |
| 40 | leukocyte aggregation (GO:0070486) | 4.17141578 |
| 41 | regulation of activation of Janus kinase activity (GO:0010533) | 4.16160490 |
| 42 | positive regulation of tolerance induction (GO:0002645) | 4.05082024 |
| 43 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.02738439 |
| 44 | negative regulation of T cell apoptotic process (GO:0070233) | 3.77443999 |
| 45 | regulation of tolerance induction (GO:0002643) | 3.74360898 |
| 46 | regulation of B cell differentiation (GO:0045577) | 3.73407113 |
| 47 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.72484958 |
| 48 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.69932123 |
| 49 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.66717383 |
| 50 | mast cell activation (GO:0045576) | 3.60582886 |
| 51 | negative regulation of T cell mediated immunity (GO:0002710) | 3.60106690 |
| 52 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.59031659 |
| 53 | T cell receptor signaling pathway (GO:0050852) | 3.56328795 |
| 54 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.54206484 |
| 55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.50560780 |
| 56 | positive regulation of B cell differentiation (GO:0045579) | 3.50372836 |
| 57 | dendritic cell chemotaxis (GO:0002407) | 3.49680282 |
| 58 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.49476284 |
| 59 | positive regulation of T cell chemotaxis (GO:0010820) | 3.48508634 |
| 60 | regulation of T cell chemotaxis (GO:0010819) | 3.48508634 |
| 61 | negative regulation of viral genome replication (GO:0045071) | 3.48051181 |
| 62 | positive regulation of defense response to virus by host (GO:0002230) | 3.47638003 |
| 63 | cellular defense response (GO:0006968) | 3.47572612 |
| 64 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.47335805 |
| 65 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.46788959 |
| 66 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.45037207 |
| 67 | positive regulation of granulocyte differentiation (GO:0030854) | 3.39832325 |
| 68 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.39261335 |
| 69 | actin nucleation (GO:0045010) | 3.35578552 |
| 70 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.31893905 |
| 71 | T cell costimulation (GO:0031295) | 3.28693589 |
| 72 | leukocyte degranulation (GO:0043299) | 3.26616774 |
| 73 | lymphocyte costimulation (GO:0031294) | 3.24487806 |
| 74 | B cell receptor signaling pathway (GO:0050853) | 3.24441050 |
| 75 | granulocyte activation (GO:0036230) | 3.21908526 |
| 76 | interferon-gamma production (GO:0032609) | 3.21660001 |
| 77 | positive regulation of T cell mediated immunity (GO:0002711) | 3.19917799 |
| 78 | neutrophil activation (GO:0042119) | 3.19536460 |
| 79 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.17226717 |
| 80 | natural killer cell activation (GO:0030101) | 3.16617424 |
| 81 | dendritic cell migration (GO:0036336) | 3.15924633 |
| 82 | negative regulation of interleukin-12 production (GO:0032695) | 3.13325391 |
| 83 | cellular extravasation (GO:0045123) | 3.12504198 |
| 84 | negative regulation by host of viral transcription (GO:0043922) | 3.12188132 |
| 85 | lymphocyte migration (GO:0072676) | 3.09755493 |
| 86 | lymphocyte chemotaxis (GO:0048247) | 3.09590065 |
| 87 | mast cell degranulation (GO:0043303) | 3.07311045 |
| 88 | mast cell activation involved in immune response (GO:0002279) | 3.07311045 |
| 89 | positive regulation of interleukin-17 production (GO:0032740) | 3.06217530 |
| 90 | regulation of lymphocyte mediated immunity (GO:0002706) | 3.04907289 |
| 91 | regulation of T cell mediated immunity (GO:0002709) | 3.04392239 |
| 92 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.03471259 |
| 93 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.00827450 |
| 94 | positive regulation of leukocyte mediated immunity (GO:0002705) | 3.00560287 |
| 95 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.98583175 |
| 96 | cytolysis (GO:0019835) | 2.98507366 |
| 97 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.97931324 |
| 98 | positive regulation of lymphocyte migration (GO:2000403) | 2.95471529 |
| 99 | respiratory burst (GO:0045730) | 2.94811438 |
| 100 | type I interferon signaling pathway (GO:0060337) | 2.90629028 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.00103127 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.99135904 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.60480064 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.15502929 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.61703029 |
| 6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.87152312 |
| 7 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.84243328 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.67113666 |
| 9 | MYB_26560356_Chip-Seq_TH2_Human | 3.65299514 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.19246267 |
| 11 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.13583267 |
| 12 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.11729870 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.00970428 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.77785048 |
| 15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.77402891 |
| 16 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.72301550 |
| 17 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.68673004 |
| 18 | MYB_26560356_Chip-Seq_TH1_Human | 2.62148712 |
| 19 | UTX_26944678_Chip-Seq_JUKART_Human | 2.58476686 |
| 20 | MAF_26560356_Chip-Seq_TH1_Human | 2.50165455 |
| 21 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.38704867 |
| 22 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.29232592 |
| 23 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.23217982 |
| 24 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.16397411 |
| 25 | GATA3_26560356_Chip-Seq_TH2_Human | 2.12098200 |
| 26 | MAF_26560356_Chip-Seq_TH2_Human | 2.07228852 |
| 27 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.01028173 |
| 28 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.94203981 |
| 29 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92500130 |
| 30 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.78139322 |
| 31 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.77465785 |
| 32 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.76617611 |
| 33 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.75551156 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75293651 |
| 35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.75245027 |
| 36 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.72812080 |
| 37 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.71926202 |
| 38 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.71267104 |
| 39 | SPI1_23127762_ChIP-Seq_K562_Human | 1.64637838 |
| 40 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63698369 |
| 41 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.60686864 |
| 42 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.57042764 |
| 43 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.48033728 |
| 44 | MYC_22102868_ChIP-Seq_BL_Human | 1.46277883 |
| 45 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.41683181 |
| 46 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.41071853 |
| 47 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.33970905 |
| 48 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.31051672 |
| 49 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.28167092 |
| 50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.24688962 |
| 51 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.20503297 |
| 52 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.19828401 |
| 53 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17654282 |
| 54 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13777140 |
| 55 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.13016829 |
| 56 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.06847686 |
| 57 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04461037 |
| 58 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01881487 |
| 59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01871828 |
| 60 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00574552 |
| 61 | GATA3_26560356_Chip-Seq_TH1_Human | 0.99038657 |
| 62 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98974260 |
| 63 | GATA1_22025678_ChIP-Seq_K562_Human | 0.97804931 |
| 64 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96744896 |
| 65 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.95498733 |
| 66 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.95408402 |
| 67 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94158815 |
| 68 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.93067631 |
| 69 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91674693 |
| 70 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.91227050 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90523997 |
| 72 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.89687979 |
| 73 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89033512 |
| 74 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.88238181 |
| 75 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.88223290 |
| 76 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.87650369 |
| 77 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.85235856 |
| 78 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.85229193 |
| 79 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.83977994 |
| 80 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.82829852 |
| 81 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.82416203 |
| 82 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.81851804 |
| 83 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.80524514 |
| 84 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.80211447 |
| 85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.80060058 |
| 86 | P300_27268052_Chip-Seq_Bcells_Human | 0.78913924 |
| 87 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.78418911 |
| 88 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.77893956 |
| 89 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.76267578 |
| 90 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.76180740 |
| 91 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.75528930 |
| 92 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.75495068 |
| 93 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.75362639 |
| 94 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.74957059 |
| 95 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74648713 |
| 96 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.74177813 |
| 97 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.73926601 |
| 98 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73671917 |
| 99 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.72258964 |
| 100 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.71740612 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.68157152 |
| 2 | MP0003763_abnormal_thymus_physiology | 4.30776740 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.98431068 |
| 4 | MP0009785_altered_susceptibility_to | 3.44631158 |
| 5 | MP0001800_abnormal_humoral_immune | 3.28001447 |
| 6 | MP0005000_abnormal_immune_tolerance | 3.26156052 |
| 7 | MP0003436_decreased_susceptibility_to | 3.16368648 |
| 8 | MP0003724_increased_susceptibility_to | 3.01648238 |
| 9 | MP0005025_abnormal_response_to | 2.98584563 |
| 10 | MP0002723_abnormal_immune_serum | 2.92557998 |
| 11 | MP0006082_CNS_inflammation | 2.90730008 |
| 12 | MP0002420_abnormal_adaptive_immunity | 2.90432668 |
| 13 | MP0001819_abnormal_immune_cell | 2.85558723 |
| 14 | MP0005387_immune_system_phenotype | 2.80378214 |
| 15 | MP0001790_abnormal_immune_system | 2.80378214 |
| 16 | MP0000685_abnormal_immune_system | 2.72521053 |
| 17 | MP0002148_abnormal_hypersensitivity_rea | 2.62733958 |
| 18 | MP0009333_abnormal_splenocyte_physiolog | 2.60222720 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.57139418 |
| 20 | MP0002419_abnormal_innate_immunity | 2.51416382 |
| 21 | MP0002398_abnormal_bone_marrow | 2.43460326 |
| 22 | MP0002405_respiratory_system_inflammati | 2.40564671 |
| 23 | MP0003866_abnormal_defecation | 2.31975274 |
| 24 | MP0000716_abnormal_immune_system | 2.27901194 |
| 25 | MP0002166_altered_tumor_susceptibility | 2.23184778 |
| 26 | MP0000703_abnormal_thymus_morphology | 2.20178875 |
| 27 | MP0010155_abnormal_intestine_physiology | 2.11273683 |
| 28 | MP0002722_abnormal_immune_system | 2.03148046 |
| 29 | MP0000689_abnormal_spleen_morphology | 2.00328770 |
| 30 | MP0005464_abnormal_platelet_physiology | 1.98743912 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.91689719 |
| 32 | MP0002429_abnormal_blood_cell | 1.80296623 |
| 33 | MP0004947_skin_inflammation | 1.75243775 |
| 34 | MP0005075_abnormal_melanosome_morpholog | 1.73807545 |
| 35 | MP0004381_abnormal_hair_follicle | 1.70531481 |
| 36 | MP0002006_tumorigenesis | 1.62228294 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.61812800 |
| 38 | MP0001873_stomach_inflammation | 1.58640208 |
| 39 | MP0003303_peritoneal_inflammation | 1.49808896 |
| 40 | MP0001533_abnormal_skeleton_physiology | 1.45066907 |
| 41 | MP0008469_abnormal_protein_level | 1.41929206 |
| 42 | MP0002933_joint_inflammation | 1.40110633 |
| 43 | MP0001853_heart_inflammation | 1.38363438 |
| 44 | MP0003878_abnormal_ear_physiology | 1.30132787 |
| 45 | MP0005377_hearing/vestibular/ear_phenot | 1.30132787 |
| 46 | MP0009764_decreased_sensitivity_to | 1.29398077 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.27307847 |
| 48 | MP0003448_altered_tumor_morphology | 1.26123805 |
| 49 | MP0000858_altered_metastatic_potential | 1.24001894 |
| 50 | MP0000569_abnormal_digit_pigmentation | 1.23623507 |
| 51 | MP0005310_abnormal_salivary_gland | 1.23177703 |
| 52 | MP0000465_gastrointestinal_hemorrhage | 1.22965693 |
| 53 | MP0003300_gastrointestinal_ulcer | 1.18430565 |
| 54 | MP0009763_increased_sensitivity_to | 1.09592748 |
| 55 | MP0003045_fibrosis | 1.07812871 |
| 56 | MP0001851_eye_inflammation | 1.03268222 |
| 57 | MP0002277_abnormal_respiratory_mucosa | 0.96830401 |
| 58 | MP0002998_abnormal_bone_remodeling | 0.93433220 |
| 59 | MP0005174_abnormal_tail_pigmentation | 0.90228598 |
| 60 | MP0002009_preneoplasia | 0.89599127 |
| 61 | MP0002138_abnormal_hepatobiliary_system | 0.89326550 |
| 62 | MP0003172_abnormal_lysosome_physiology | 0.85479926 |
| 63 | MP0002132_abnormal_respiratory_system | 0.82408516 |
| 64 | MP0000015_abnormal_ear_pigmentation | 0.80936256 |
| 65 | MP0002019_abnormal_tumor_incidence | 0.80815823 |
| 66 | MP0009765_abnormal_xenobiotic_induced | 0.77925807 |
| 67 | MP0002163_abnormal_gland_morphology | 0.76995142 |
| 68 | MP0005166_decreased_susceptibility_to | 0.73921432 |
| 69 | MP0002877_abnormal_melanocyte_morpholog | 0.69292490 |
| 70 | MP0003786_premature_aging | 0.68170936 |
| 71 | MP0001919_abnormal_reproductive_system | 0.65930999 |
| 72 | MP0008873_increased_physiological_sensi | 0.65275857 |
| 73 | MP0004130_abnormal_muscle_cell | 0.62946884 |
| 74 | MP0001765_abnormal_ion_homeostasis | 0.62764812 |
| 75 | MP0010307_abnormal_tumor_latency | 0.57873977 |
| 76 | MP0008877_abnormal_DNA_methylation | 0.57872671 |
| 77 | MP0003252_abnormal_bile_duct | 0.57042725 |
| 78 | MP0002693_abnormal_pancreas_physiology | 0.56961797 |
| 79 | MP0003075_altered_response_to | 0.55998839 |
| 80 | MP0000490_abnormal_crypts_of | 0.55601913 |
| 81 | MP0002876_abnormal_thyroid_physiology | 0.54864719 |
| 82 | MP0005390_skeleton_phenotype | 0.53759446 |
| 83 | MP0003191_abnormal_cellular_cholesterol | 0.53526750 |
| 84 | MP0000249_abnormal_blood_vessel | 0.52994177 |
| 85 | MP0004883_abnormal_blood_vessel | 0.51918448 |
| 86 | MP0006054_spinal_hemorrhage | 0.50521764 |
| 87 | MP0001986_abnormal_taste_sensitivity | 0.49910510 |
| 88 | MP0004147_increased_porphyrin_level | 0.49832665 |
| 89 | MP0003828_pulmonary_edema | 0.49819504 |
| 90 | MP0004808_abnormal_hematopoietic_stem | 0.49537245 |
| 91 | MP0002136_abnormal_kidney_physiology | 0.49506403 |
| 92 | MP0001663_abnormal_digestive_system | 0.47126310 |
| 93 | MP0005319_abnormal_enzyme/_coenzyme | 0.46331250 |
| 94 | MP0003795_abnormal_bone_structure | 0.46069809 |
| 95 | MP0000920_abnormal_myelination | 0.43574684 |
| 96 | MP0005083_abnormal_biliary_tract | 0.43489270 |
| 97 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.42660088 |
| 98 | MP0002095_abnormal_skin_pigmentation | 0.41320167 |
| 99 | MP0009643_abnormal_urine_homeostasis | 0.41309335 |
| 100 | MP0001501_abnormal_sleep_pattern | 0.40745125 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.89877347 |
| 2 | Abnormality of T cell number (HP:0011839) | 6.56324376 |
| 3 | Myositis (HP:0100614) | 5.17350613 |
| 4 | Retrobulbar optic neuritis (HP:0100654) | 5.05159944 |
| 5 | Optic neuritis (HP:0100653) | 5.05159944 |
| 6 | Abnormality of T cells (HP:0002843) | 4.97160276 |
| 7 | Severe combined immunodeficiency (HP:0004430) | 4.86126452 |
| 8 | IgG deficiency (HP:0004315) | 4.83379969 |
| 9 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.77043984 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.71362951 |
| 11 | Orchitis (HP:0100796) | 4.66039098 |
| 12 | Encephalitis (HP:0002383) | 4.62476953 |
| 13 | Increased IgM level (HP:0003496) | 4.52210862 |
| 14 | Autoimmune hemolytic anemia (HP:0001890) | 4.28868742 |
| 15 | Abnormality of eosinophils (HP:0001879) | 4.27505444 |
| 16 | Stomatitis (HP:0010280) | 4.24076496 |
| 17 | Meningitis (HP:0001287) | 4.19343898 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.98976397 |
| 19 | Combined immunodeficiency (HP:0005387) | 3.87529065 |
| 20 | Eczematoid dermatitis (HP:0000976) | 3.85452388 |
| 21 | Eosinophilia (HP:0001880) | 3.85015255 |
| 22 | Granulocytopenia (HP:0001913) | 3.78700815 |
| 23 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.75177351 |
| 24 | Recurrent cutaneous fungal infections (HP:0011370) | 3.75177351 |
| 25 | Keratoconjunctivitis sicca (HP:0001097) | 3.74664516 |
| 26 | Pulmonary infiltrates (HP:0002113) | 3.68630130 |
| 27 | Vasculitis (HP:0002633) | 3.65189400 |
| 28 | Leukocytosis (HP:0001974) | 3.62559119 |
| 29 | Recurrent abscess formation (HP:0002722) | 3.60401217 |
| 30 | Hypoproteinemia (HP:0003075) | 3.59685641 |
| 31 | Keratoconjunctivitis (HP:0001096) | 3.58461859 |
| 32 | Panhypogammaglobulinemia (HP:0003139) | 3.51839879 |
| 33 | Chronic diarrhea (HP:0002028) | 3.50385917 |
| 34 | Recurrent bacterial skin infections (HP:0005406) | 3.48915364 |
| 35 | Gastrointestinal infarctions (HP:0005244) | 3.48523180 |
| 36 | Recurrent bronchitis (HP:0002837) | 3.47371512 |
| 37 | Abnormality of T cell physiology (HP:0011840) | 3.45646161 |
| 38 | Abnormality of macrophages (HP:0004311) | 3.41712459 |
| 39 | Abnormality of B cell number (HP:0010975) | 3.39555978 |
| 40 | Recurrent viral infections (HP:0004429) | 3.39006810 |
| 41 | Hemoptysis (HP:0002105) | 3.33480071 |
| 42 | Thyroiditis (HP:0100646) | 3.33151451 |
| 43 | Obstructive lung disease (HP:0006536) | 3.30238515 |
| 44 | Chronic obstructive pulmonary disease (HP:0006510) | 3.30238515 |
| 45 | Mediastinal lymphadenopathy (HP:0100721) | 3.22877364 |
| 46 | Pustule (HP:0200039) | 3.16285373 |
| 47 | Lymphopenia (HP:0001888) | 3.14751642 |
| 48 | Autoimmune thrombocytopenia (HP:0001973) | 3.09319837 |
| 49 | B lymphocytopenia (HP:0010976) | 3.08030506 |
| 50 | Gangrene (HP:0100758) | 3.03898617 |
| 51 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.03802644 |
| 52 | Recurrent skin infections (HP:0001581) | 2.98101184 |
| 53 | Chest pain (HP:0100749) | 2.92891615 |
| 54 | Abnormality of the prostate (HP:0008775) | 2.91815231 |
| 55 | Joint swelling (HP:0001386) | 2.89102015 |
| 56 | Pulmonary embolism (HP:0002204) | 2.87060724 |
| 57 | Arterial thrombosis (HP:0004420) | 2.78882025 |
| 58 | Hypergammaglobulinemia (HP:0010702) | 2.78533108 |
| 59 | Agammaglobulinemia (HP:0004432) | 2.76784311 |
| 60 | Abnormality of the pleura (HP:0002103) | 2.67551445 |
| 61 | Hypoplasia of the thymus (HP:0000778) | 2.67047453 |
| 62 | IgM deficiency (HP:0002850) | 2.65428609 |
| 63 | Anorexia (HP:0002039) | 2.58690226 |
| 64 | Acute hepatic failure (HP:0006554) | 2.49969953 |
| 65 | Increased IgE level (HP:0003212) | 2.43881391 |
| 66 | Lymphoma (HP:0002665) | 2.37020958 |
| 67 | Spontaneous hematomas (HP:0007420) | 2.35932598 |
| 68 | Hemiplegia (HP:0002301) | 2.35616631 |
| 69 | Glomerulopathy (HP:0100820) | 2.33593358 |
| 70 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.30455980 |
| 71 | Aplastic anemia (HP:0001915) | 2.21359374 |
| 72 | Inflammation of the large intestine (HP:0002037) | 2.19309579 |
| 73 | Keratitis (HP:0000491) | 2.16395563 |
| 74 | Hypochromic anemia (HP:0001931) | 2.15520595 |
| 75 | Polyneuropathy (HP:0001271) | 2.11598751 |
| 76 | Epistaxis (HP:0000421) | 2.11133405 |
| 77 | Urticaria (HP:0001025) | 2.05457407 |
| 78 | Gastrointestinal inflammation (HP:0004386) | 2.05171907 |
| 79 | Bronchitis (HP:0012387) | 2.04564321 |
| 80 | Papilledema (HP:0001085) | 2.02404632 |
| 81 | Stomach cancer (HP:0012126) | 1.99109762 |
| 82 | Acne (HP:0001061) | 1.95489805 |
| 83 | Prolonged bleeding time (HP:0003010) | 1.94731350 |
| 84 | Thrombophlebitis (HP:0004418) | 1.93988675 |
| 85 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92890012 |
| 86 | Skin rash (HP:0000988) | 1.91856426 |
| 87 | Abnormality of the pericardium (HP:0001697) | 1.87969733 |
| 88 | Pulmonary fibrosis (HP:0002206) | 1.87447609 |
| 89 | Gingivitis (HP:0000230) | 1.85868400 |
| 90 | Petechiae (HP:0000967) | 1.84657890 |
| 91 | Vertigo (HP:0002321) | 1.82942520 |
| 92 | Gingival bleeding (HP:0000225) | 1.80182805 |
| 93 | Increased CSF protein (HP:0002922) | 1.76822396 |
| 94 | Amaurosis fugax (HP:0100576) | 1.76453644 |
| 95 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.76260522 |
| 96 | Sepsis (HP:0100806) | 1.75642995 |
| 97 | Alveolar cell carcinoma (HP:0006519) | 1.73577995 |
| 98 | Ureteral stenosis (HP:0000071) | 1.73317630 |
| 99 | Increased serum ferritin (HP:0003281) | 1.71873086 |
| 100 | Recurrent otitis media (HP:0000403) | 1.68437859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.97110997 |
| 2 | MAP4K1 | 4.70148713 |
| 3 | FES | 3.78272810 |
| 4 | KDR | 3.07927313 |
| 5 | RIPK4 | 2.85868006 |
| 6 | TAOK3 | 2.77037783 |
| 7 | GRK6 | 2.72199033 |
| 8 | ZAP70 | 2.47509575 |
| 9 | TESK2 | 2.43035942 |
| 10 | CSK | 2.37352742 |
| 11 | ITK | 2.36879547 |
| 12 | SYK | 1.94162921 |
| 13 | BTK | 1.86112683 |
| 14 | IKBKE | 1.82413337 |
| 15 | MAP3K14 | 1.80608090 |
| 16 | LCK | 1.76037438 |
| 17 | JAK3 | 1.73617146 |
| 18 | JAK1 | 1.69690477 |
| 19 | GRK7 | 1.59636812 |
| 20 | TEC | 1.49591247 |
| 21 | BLK | 1.48119065 |
| 22 | LYN | 1.44719091 |
| 23 | TYK2 | 1.44650977 |
| 24 | TNK2 | 1.44330450 |
| 25 | TBK1 | 1.43472401 |
| 26 | KIT | 1.42742245 |
| 27 | IRAK4 | 1.40467273 |
| 28 | HCK | 1.37114044 |
| 29 | PRKCQ | 1.35440829 |
| 30 | STK10 | 1.29626128 |
| 31 | MARK3 | 1.24232120 |
| 32 | IKBKB | 1.22397720 |
| 33 | SIK3 | 1.20901946 |
| 34 | BCKDK | 1.17947124 |
| 35 | PIK3CG | 1.11653476 |
| 36 | TGFBR2 | 1.09385755 |
| 37 | MST4 | 1.09073563 |
| 38 | ADRBK2 | 1.05138877 |
| 39 | CSF1R | 1.01996451 |
| 40 | BMPR2 | 0.98920701 |
| 41 | MATK | 0.98561023 |
| 42 | MAP3K11 | 0.97402243 |
| 43 | PIM1 | 0.93137149 |
| 44 | TYRO3 | 0.92354528 |
| 45 | JAK2 | 0.90225910 |
| 46 | ZAK | 0.90220149 |
| 47 | MAP2K6 | 0.89381752 |
| 48 | MAP2K3 | 0.88156953 |
| 49 | NLK | 0.86144545 |
| 50 | MAP3K12 | 0.83902198 |
| 51 | TLK1 | 0.81867730 |
| 52 | PRPF4B | 0.71484478 |
| 53 | FYN | 0.69371610 |
| 54 | CAMKK2 | 0.68409914 |
| 55 | PIK3CA | 0.67830958 |
| 56 | CLK1 | 0.67126772 |
| 57 | PDK1 | 0.65950343 |
| 58 | NUAK1 | 0.64810134 |
| 59 | MAPK11 | 0.64194241 |
| 60 | SCYL2 | 0.62392560 |
| 61 | EPHB1 | 0.59977592 |
| 62 | MAPKAPK2 | 0.55848801 |
| 63 | VRK1 | 0.54077386 |
| 64 | MAP2K2 | 0.52413266 |
| 65 | FGFR4 | 0.51834860 |
| 66 | MAP3K3 | 0.51680932 |
| 67 | TRIM28 | 0.51585809 |
| 68 | HIPK2 | 0.51523339 |
| 69 | SIK2 | 0.51245260 |
| 70 | TESK1 | 0.50865573 |
| 71 | EPHA3 | 0.48700858 |
| 72 | TRPM7 | 0.47259729 |
| 73 | CDK4 | 0.46974769 |
| 74 | FGFR3 | 0.45189549 |
| 75 | IGF1R | 0.43452158 |
| 76 | TAOK1 | 0.42506425 |
| 77 | MAP3K13 | 0.41111144 |
| 78 | FGR | 0.40544269 |
| 79 | MAPK7 | 0.39283713 |
| 80 | IRAK1 | 0.38316837 |
| 81 | MAP3K1 | 0.36725560 |
| 82 | MAP3K5 | 0.34922662 |
| 83 | GRK5 | 0.33900523 |
| 84 | INSR | 0.33587871 |
| 85 | MAPK12 | 0.32229430 |
| 86 | MOS | 0.29074717 |
| 87 | CHUK | 0.28477710 |
| 88 | CAMKK1 | 0.28270468 |
| 89 | PDGFRB | 0.28153461 |
| 90 | EIF2AK2 | 0.27382883 |
| 91 | LRRK2 | 0.27191185 |
| 92 | ERN1 | 0.24291160 |
| 93 | MAPKAPK3 | 0.22968939 |
| 94 | MAPK3 | 0.21829626 |
| 95 | ABL1 | 0.21341333 |
| 96 | RPS6KA4 | 0.20988865 |
| 97 | RPS6KA5 | 0.20016922 |
| 98 | PRKCH | 0.19507839 |
| 99 | FRK | 0.17227815 |
| 100 | MELK | 0.17120855 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.58339519 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.02996688 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.88613386 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.34409425 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.26206780 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.21367390 |
| 7 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.19132934 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.83020286 |
| 9 | Measles_Homo sapiens_hsa05162 | 2.42452554 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.42282973 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.40594507 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.26581493 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.22330040 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.86607014 |
| 15 | Leishmaniasis_Homo sapiens_hsa05140 | 1.85814230 |
| 16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.84078811 |
| 17 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.77333890 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.71676838 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.68936634 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.67682928 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.64869767 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.64645437 |
| 23 | Malaria_Homo sapiens_hsa05144 | 1.63069822 |
| 24 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.53287475 |
| 25 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.52403750 |
| 26 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.50480285 |
| 27 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.49416203 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.48815736 |
| 29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.45739434 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.42925193 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.34066473 |
| 32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.25841245 |
| 33 | Salmonella infection_Homo sapiens_hsa05132 | 1.24575076 |
| 34 | Proteasome_Homo sapiens_hsa03050 | 1.24213274 |
| 35 | Shigellosis_Homo sapiens_hsa05131 | 1.23622327 |
| 36 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.15150914 |
| 37 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.09095763 |
| 38 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.06396445 |
| 39 | Apoptosis_Homo sapiens_hsa04210 | 1.02173345 |
| 40 | Tuberculosis_Homo sapiens_hsa05152 | 1.00714050 |
| 41 | Influenza A_Homo sapiens_hsa05164 | 0.99916803 |
| 42 | Legionellosis_Homo sapiens_hsa05134 | 0.93820975 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.87160797 |
| 44 | Hepatitis B_Homo sapiens_hsa05161 | 0.86968613 |
| 45 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.81501639 |
| 46 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.76369206 |
| 47 | Platelet activation_Homo sapiens_hsa04611 | 0.75409950 |
| 48 | HTLV-I infection_Homo sapiens_hsa05166 | 0.75116728 |
| 49 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.70359693 |
| 50 | Pertussis_Homo sapiens_hsa05133 | 0.69221627 |
| 51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.66111506 |
| 52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.63769478 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.62642973 |
| 54 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52983307 |
| 55 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.50718435 |
| 56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.50413742 |
| 57 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.50183836 |
| 58 | Endocytosis_Homo sapiens_hsa04144 | 0.48603437 |
| 59 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.47134697 |
| 60 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.46771540 |
| 61 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45206667 |
| 62 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44286105 |
| 63 | Hepatitis C_Homo sapiens_hsa05160 | 0.42936488 |
| 64 | Phagosome_Homo sapiens_hsa04145 | 0.42678941 |
| 65 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.38968801 |
| 66 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.36189478 |
| 67 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35703990 |
| 68 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.33817357 |
| 69 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.31859898 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30707799 |
| 71 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.30158892 |
| 72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.29126681 |
| 73 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.27227951 |
| 74 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.26885407 |
| 75 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.25553876 |
| 76 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.23841978 |
| 77 | Prion diseases_Homo sapiens_hsa05020 | 0.23016420 |
| 78 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.21712417 |
| 79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.21570003 |
| 80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.19614930 |
| 81 | Colorectal cancer_Homo sapiens_hsa05210 | 0.17221367 |
| 82 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.16952563 |
| 83 | Lysosome_Homo sapiens_hsa04142 | 0.16013444 |
| 84 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.15703645 |
| 85 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.15682578 |
| 86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.13973398 |
| 87 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.12906352 |
| 88 | Insulin resistance_Homo sapiens_hsa04931 | 0.11885422 |
| 89 | RNA polymerase_Homo sapiens_hsa03020 | 0.10713016 |
| 90 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.09085657 |
| 91 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.08201739 |
| 92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.07752226 |
| 93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.06238671 |
| 94 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.05763367 |
| 95 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.04970956 |
| 96 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.03764968 |
| 97 | RNA degradation_Homo sapiens_hsa03018 | 0.03583841 |
| 98 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.03355411 |
| 99 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.02748770 |
| 100 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.02433665 |

