TRGJ1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)8.08467237
2ribosomal small subunit assembly (GO:0000028)7.87220785
3positive regulation of gamma-delta T cell activation (GO:0046645)7.54956790
4positive T cell selection (GO:0043368)7.42747691
5mitotic chromosome condensation (GO:0007076)6.94230756
6V(D)J recombination (GO:0033151)6.69297893
7negative T cell selection (GO:0043383)6.47857324
8Arp2/3 complex-mediated actin nucleation (GO:0034314)6.09432753
9regulation of gamma-delta T cell differentiation (GO:0045586)5.99879293
10regulation of regulatory T cell differentiation (GO:0045589)5.74484133
11eosinophil chemotaxis (GO:0048245)5.71205978
12positive regulation of natural killer cell mediated immunity (GO:0002717)5.64825854
13regulation of histone H3-K9 methylation (GO:0051570)5.62521551
14positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)5.60918211
15mast cell activation (GO:0045576)5.57596877
16regulation of B cell receptor signaling pathway (GO:0050855)5.53838051
17negative regulation by host of viral transcription (GO:0043922)5.50360984
18regulation of gamma-delta T cell activation (GO:0046643)5.41935706
19actin nucleation (GO:0045010)5.33637296
20negative regulation of viral genome replication (GO:0045071)5.31973899
21pyrimidine nucleoside catabolic process (GO:0046135)5.29180203
22regulation of activation of Janus kinase activity (GO:0010533)5.25701015
23antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.23127115
24antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.23127115
25eosinophil migration (GO:0072677)5.17708775
26negative regulation of T cell apoptotic process (GO:0070233)5.05497662
27cellular hyperosmotic response (GO:0071474)5.02106574
28cytolysis (GO:0019835)4.87753310
29regulation of T cell tolerance induction (GO:0002664)4.84118968
30positive regulation of tolerance induction (GO:0002645)4.83384104
31regulation of natural killer cell mediated immunity (GO:0002715)4.82816671
32regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.82816671
33antigen processing and presentation of endogenous antigen (GO:0019883)4.80985608
34mitotic sister chromatid cohesion (GO:0007064)4.79995137
35T cell selection (GO:0045058)4.77529760
36positive regulation of calcium-mediated signaling (GO:0050850)4.70334691
37positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.70245068
38positive regulation of granulocyte differentiation (GO:0030854)4.68036947
39regulation of chronic inflammatory response (GO:0002676)4.65038497
40macrophage chemotaxis (GO:0048246)4.64929222
41regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.58795964
42T cell receptor signaling pathway (GO:0050852)4.45658845
43negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.44506425
44negative regulation of cell killing (GO:0031342)4.44506425
45positive regulation of interleukin-8 secretion (GO:2000484)4.40434748
46regulation of lymphocyte chemotaxis (GO:1901623)4.37646941
47positive regulation of translational initiation (GO:0045948)4.36651562
48ribosomal small subunit biogenesis (GO:0042274)4.35167163
49meiotic chromosome segregation (GO:0045132)4.34319054
50negative regulation of histone methylation (GO:0031061)4.32925689
51cellular response to interleukin-15 (GO:0071350)4.27017596
52positive regulation of monocyte chemotaxis (GO:0090026)4.26937803
53sister chromatid segregation (GO:0000819)4.23062854
54regulation of leukocyte mediated cytotoxicity (GO:0001910)4.22667097
55DNA unwinding involved in DNA replication (GO:0006268)4.21493948
56pinocytosis (GO:0006907)4.20649681
57antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.18659619
58viral transcription (GO:0019083)4.17526440
59positive regulation of cell killing (GO:0031343)4.15451213
60toxin transport (GO:1901998)4.10662617
61regulation of T cell chemotaxis (GO:0010819)4.07852613
62positive regulation of T cell chemotaxis (GO:0010820)4.07852613
63translational termination (GO:0006415)4.05702948
64antigen receptor-mediated signaling pathway (GO:0050851)4.02699387
65alternative mRNA splicing, via spliceosome (GO:0000380)4.01472808
66monocyte chemotaxis (GO:0002548)3.97633248
67positive regulation of T cell apoptotic process (GO:0070234)3.97250922
68regulation of tolerance induction (GO:0002643)3.92619883
69regulation of T cell receptor signaling pathway (GO:0050856)3.91389917
70DNA ligation (GO:0006266)3.85289596
71regulation of chemokine-mediated signaling pathway (GO:0070099)3.85046853
72positive regulation of megakaryocyte differentiation (GO:0045654)3.81862899
73regulation of cell killing (GO:0031341)3.77245620
74protein localization to kinetochore (GO:0034501)3.77097828
75mitotic sister chromatid segregation (GO:0000070)3.76320965
76definitive hemopoiesis (GO:0060216)3.69403437
77mast cell activation involved in immune response (GO:0002279)3.67078302
78mast cell degranulation (GO:0043303)3.67078302
79regulation of mononuclear cell migration (GO:0071675)3.65946017
80regulation of viral genome replication (GO:0045069)3.65042124
81histamine transport (GO:0051608)3.64762900
82positive regulation of T cell mediated cytotoxicity (GO:0001916)3.64640480
83regulation of calcium-mediated signaling (GO:0050848)3.59032629
84activated T cell proliferation (GO:0050798)3.57952433
85somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.57758028
86somatic cell DNA recombination (GO:0016444)3.57758028
87lymphocyte costimulation (GO:0031294)3.55798705
88T cell costimulation (GO:0031295)3.55173140
89negative regulation of B cell proliferation (GO:0030889)3.54384504
90regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.53090092
91regulation of T cell apoptotic process (GO:0070232)3.49655473
92positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.49331724
93response to interleukin-15 (GO:0070672)3.45810025
94regulation of interleukin-8 secretion (GO:2000482)3.43547349
95regulation of phospholipase A2 activity (GO:0032429)3.42953634
96negative regulation of lymphocyte apoptotic process (GO:0070229)3.42104580
97antigen processing and presentation via MHC class Ib (GO:0002475)3.41670576
98chromosome condensation (GO:0030261)3.40166689
99negative regulation of phagocytosis (GO:0050765)3.39513132
100positive regulation of keratinocyte differentiation (GO:0045618)3.39494187
101positive thymic T cell selection (GO:0045059)3.38913545
102natural killer cell differentiation (GO:0001779)3.38125299
103regulation of T cell mediated cytotoxicity (GO:0001914)3.36078587
104regulation of macrophage chemotaxis (GO:0010758)3.35161763
105positive regulation of B cell differentiation (GO:0045579)3.34881264
106positive regulation of lymphocyte migration (GO:2000403)3.34578179
107negative regulation of viral process (GO:0048525)3.34391756
108nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.34292450
109B cell receptor signaling pathway (GO:0050853)3.29679000
110cellular protein complex disassembly (GO:0043624)3.28651475
111translational elongation (GO:0006414)3.28228232
112negative thymic T cell selection (GO:0045060)3.27777898
113mucosal-associated lymphoid tissue development (GO:0048537)3.25910819
114Peyers patch development (GO:0048541)3.25910819
115GDP-mannose metabolic process (GO:0019673)3.25666077
116intracellular pH reduction (GO:0051452)3.25562488
117attachment of spindle microtubules to kinetochore (GO:0008608)3.21344785
118DNA topological change (GO:0006265)3.20632588
119positive regulation of histone H3-K4 methylation (GO:0051571)3.20353311
120negative regulation of viral transcription (GO:0032897)3.17716984
121dendritic cell chemotaxis (GO:0002407)3.17633111
122negative regulation of calcium ion transport into cytosol (GO:0010523)3.16349740
123negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.16203803
124T cell differentiation in thymus (GO:0033077)3.15407957
125regulation of histone H3-K4 methylation (GO:0051569)3.14828742
126positive regulation of interleukin-4 production (GO:0032753)3.13755102
127somatic diversification of immune receptors (GO:0002200)3.13751941
128sequestering of actin monomers (GO:0042989)3.13647798
129regulation of interleukin-2 biosynthetic process (GO:0045076)3.13608681
130regulation of erythrocyte differentiation (GO:0045646)3.12947272
131SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.11784886
132protein complex disassembly (GO:0043241)3.10069356
133cotranslational protein targeting to membrane (GO:0006613)3.08354072
134positive regulation of histone methylation (GO:0031062)3.05765507
135protein targeting to ER (GO:0045047)3.05304510
136establishment of integrated proviral latency (GO:0075713)3.04101986
137pyrimidine-containing compound catabolic process (GO:0072529)3.00535062
138regulation of DNA endoreduplication (GO:0032875)2.99908394
139T cell differentiation (GO:0030217)2.99834313
140establishment of protein localization to endoplasmic reticulum (GO:0072599)2.94191635
141positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.92806649
142positive regulation of lamellipodium assembly (GO:0010592)2.92394204
143adaptation of signaling pathway (GO:0023058)2.91092991
144ncRNA 3-end processing (GO:0043628)2.91043570
145viral life cycle (GO:0019058)2.90712284
146antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.89906028
147positive regulation of lymphocyte apoptotic process (GO:0070230)2.89789600
148kinetochore organization (GO:0051383)2.89602488
149thymic T cell selection (GO:0045061)2.88558038
150immune response-activating cell surface receptor signaling pathway (GO:0002429)2.88077187
151megakaryocyte development (GO:0035855)2.87386588
152response to interferon-beta (GO:0035456)2.87087920
153positive regulation of lymphocyte mediated immunity (GO:0002708)2.86947156
154negative regulation of B cell activation (GO:0050869)2.86603026
155metallo-sulfur cluster assembly (GO:0031163)2.84223779
156iron-sulfur cluster assembly (GO:0016226)2.84223779
157regulation of extracellular matrix disassembly (GO:0010715)2.82493923
158modulation by host of symbiont transcription (GO:0052472)2.80765250
159modulation by host of viral transcription (GO:0043921)2.80765250
160protein localization to chromosome, centromeric region (GO:0071459)2.79724612
161negative regulation of actin filament bundle assembly (GO:0032232)2.79555764
162protein localization to endoplasmic reticulum (GO:0070972)2.79368353
163DNA demethylation (GO:0080111)2.79267607
164negative regulation of stress fiber assembly (GO:0051497)2.79243528
165DNA packaging (GO:0006323)2.78591919
166regulation of B cell differentiation (GO:0045577)2.78125787
167regulation of histone methylation (GO:0031060)2.77406137
168macromolecular complex disassembly (GO:0032984)2.75912569
169nucleosome assembly (GO:0006334)2.74938991
170T cell lineage commitment (GO:0002360)2.73821126
171membrane raft organization (GO:0031579)2.70930508
172nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.70159902
173T cell migration (GO:0072678)2.68908434
174cytidine deamination (GO:0009972)12.4576619
175cytidine metabolic process (GO:0046087)12.4576619
176cytidine catabolic process (GO:0006216)12.4576619
177pyrimidine ribonucleoside catabolic process (GO:0046133)11.0371377
178DNA deamination (GO:0045006)10.4096208

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.32858925
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.09401243
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.30513180
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.00020277
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.88179796
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.42177297
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.32892053
8EGR1_19374776_ChIP-ChIP_THP-1_Human3.10605383
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.08462070
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.07198552
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.94617726
12SCL_19346495_ChIP-Seq_HPC-7_Human2.83036215
13RUNX_20019798_ChIP-Seq_JUKART_Human2.60321957
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.49249959
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.42947434
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.28256041
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.18531871
18RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.17460340
19MYC_22102868_ChIP-Seq_BL_Human2.15224931
20MYB_26560356_Chip-Seq_TH2_Human2.09422132
21IRF8_22096565_ChIP-ChIP_GC-B_Human2.07162440
22IRF8_21731497_ChIP-ChIP_J774_Mouse2.01479560
23STAT4_19710469_ChIP-ChIP_TH1__Mouse2.00371996
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse12.5125174
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.96282628
26CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.91649862
27FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.90849782
28FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.88503886
29RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.85608239
30UTX_26944678_Chip-Seq_JUKART_Human1.75816842
31MYB_21317192_ChIP-Seq_ERMYB_Mouse1.74258158
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.72715882
33IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.72396438
34MAF_26560356_Chip-Seq_TH1_Human1.70778835
35RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.67906415
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59646422
37VDR_22108803_ChIP-Seq_LS180_Human1.56888230
38GATA3_27048872_Chip-Seq_THYMUS_Human1.56657456
39MYB_26560356_Chip-Seq_TH1_Human1.53900487
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.49977565
41NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.49873832
42VDR_21846776_ChIP-Seq_THP-1_Human1.49209297
43TCF7_22412390_ChIP-Seq_EML_Mouse1.48309339
44RUNX1_22412390_ChIP-Seq_EML_Mouse1.47091050
45TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.46823883
46EGR1_23403033_ChIP-Seq_LIVER_Mouse1.45702510
47BRD4_27068464_Chip-Seq_AML-cells_Mouse1.44752721
48HTT_18923047_ChIP-ChIP_STHdh_Human1.41683307
49VDR_24763502_ChIP-Seq_THP-1_Human1.41270190
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.40194390
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.40097776
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.39527258
53PCGF2_27294783_Chip-Seq_NPCs_Mouse1.37987255
54RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.36509595
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36427291
56SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33878808
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.33584723
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.30733101
59IRF8_27001747_Chip-Seq_BMDM_Mouse1.29579542
60KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.28651379
61EST1_17652178_ChIP-ChIP_JURKAT_Human1.28141440
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28066988
63ELK1_19687146_ChIP-ChIP_HELA_Human1.26762607
64GATA1_22025678_ChIP-Seq_K562_Human1.25989394
65PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.25903429
66PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25030643
67E2F1_21310950_ChIP-Seq_MCF-7_Human1.23745004
68BCL6_27268052_Chip-Seq_Bcells_Human1.21594605
69CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.19410896
70KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.17869001
71EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.17575352
72TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.17354245
73SPI1_23547873_ChIP-Seq_NB4_Human1.16993902
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.16461720
75SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.13969368
76LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.13938889
77AR_21909140_ChIP-Seq_LNCAP_Human1.13839489
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.12654435
79GATA2_22383799_ChIP-Seq_G1ME_Mouse1.12443035
80GABP_17652178_ChIP-ChIP_JURKAT_Human1.11633916
81SPI1_23127762_ChIP-Seq_K562_Human1.11475711
82EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.05750379
83FLI1_27457419_Chip-Seq_LIVER_Mouse1.03165512
84MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.03012828
85KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01844359
86NFE2_27457419_Chip-Seq_LIVER_Mouse1.01654415
87LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.01295348
88ETS1_22383799_ChIP-Seq_G1ME_Mouse1.01071005
89STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00788516
90TP53_22573176_ChIP-Seq_HFKS_Human1.00390684
91TAF2_19829295_ChIP-Seq_ESCs_Human0.99446890
92NANOG_20526341_ChIP-Seq_ESCs_Human0.97442578
93NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.96886571
94PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96392756
95JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.94202921
96MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.93997220
97ELF1_17652178_ChIP-ChIP_JURKAT_Human0.93149996
98AR_21572438_ChIP-Seq_LNCaP_Human0.92772087
99MYC_18555785_ChIP-Seq_MESCs_Mouse0.91965750
100HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.91010246
101YY1_22570637_ChIP-Seq_MALME-3M_Human0.90735038
102CTCF_20526341_ChIP-Seq_ESCs_Human0.90657267
103GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90103731
104GATA1_22383799_ChIP-Seq_G1ME_Mouse0.89846192
105RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88698240
106GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88616638
107GATA3_26560356_Chip-Seq_TH1_Human0.88440826
108VDR_23849224_ChIP-Seq_CD4+_Human0.88386370
109EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88295734
110E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.87919644
111SUZ12_27294783_Chip-Seq_NPCs_Mouse0.87883257
112GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.87617820
113PU_27001747_Chip-Seq_BMDM_Mouse0.87613483
114POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87430132
115MAF_26560356_Chip-Seq_TH2_Human0.86000526
116NANOG_19829295_ChIP-Seq_ESCs_Human0.84314738
117SOX2_19829295_ChIP-Seq_ESCs_Human0.84314738
118ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.83731642
119SA1_27219007_Chip-Seq_Bcells_Human0.82948864
120P300_27268052_Chip-Seq_Bcells_Human0.82923619
121FOXA1_27270436_Chip-Seq_PROSTATE_Human0.82153662
122FOXA1_25329375_ChIP-Seq_VCAP_Human0.82153662
123GATA3_26560356_Chip-Seq_TH2_Human0.81254232
124EZH2_27294783_Chip-Seq_NPCs_Mouse0.81120693
125AR_20517297_ChIP-Seq_VCAP_Human0.80699957
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.80302253
127BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.80180327
128TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.79910193
129IRF1_19129219_ChIP-ChIP_H3396_Human0.79448023
130GATA6_21074721_ChIP-Seq_CACO-2_Human0.79061066
131KDM2B_26808549_Chip-Seq_DND41_Human0.79048420
132CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.78997125
133MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.78643151
134CIITA_25753668_ChIP-Seq_RAJI_Human0.77988044
135FOXP3_21729870_ChIP-Seq_TREG_Human0.77429076
136TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77375824
137GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.77357233
138ELF1_20517297_ChIP-Seq_JURKAT_Human0.77210344
139HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75239539
140VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.74781316
141FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74107405
142GATA3_21878914_ChIP-Seq_MCF-7_Human0.73178506
143ERA_21632823_ChIP-Seq_H3396_Human0.72405516
144AUTS2_25519132_ChIP-Seq_293T-REX_Human0.71960055
145EZH2_22144423_ChIP-Seq_EOC_Human0.71396284
146SRY_22984422_ChIP-ChIP_TESTIS_Rat0.70771924
147SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.70715925
148MYC_19079543_ChIP-ChIP_MESCs_Mouse0.70674403
149POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.70484833
150GATA1_19941827_ChIP-Seq_MEL_Mouse0.70350872
151FOXH1_21741376_ChIP-Seq_EPCs_Human0.70291001
152RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.70277958
153SOX2_18555785_ChIP-Seq_MESCs_Mouse0.69477710
154PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.68851784
155MYC_19030024_ChIP-ChIP_MESCs_Mouse0.66975471
156XRN2_22483619_ChIP-Seq_HELA_Human0.63340647
157SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.61528810
158SOX2_16153702_ChIP-ChIP_HESCs_Human0.60256167
159MYC_18940864_ChIP-ChIP_HL60_Human0.59568829
160SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.58742009
161ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.56796779

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.97871992
2MP0001835_abnormal_antigen_presentation3.92871946
3MP0003763_abnormal_thymus_physiology3.92041578
4MP0000685_abnormal_immune_system3.47209046
5MP0002166_altered_tumor_susceptibility3.42052118
6MP0001873_stomach_inflammation3.19439101
7MP0000703_abnormal_thymus_morphology2.99658629
8MP0005671_abnormal_response_to2.85702271
9MP0002398_abnormal_bone_marrow2.82731930
10MP0010094_abnormal_chromosome_stability2.78540470
11MP0005397_hematopoietic_system_phenotyp2.77748681
12MP0001545_abnormal_hematopoietic_system2.77748681
13MP0002006_tumorigenesis2.76934515
14MP0008007_abnormal_cellular_replicative2.54315033
15MP0004808_abnormal_hematopoietic_stem2.52081700
16MP0010352_gastrointestinal_tract_polyps2.51334277
17MP0008877_abnormal_DNA_methylation2.41259422
18MP0001800_abnormal_humoral_immune2.36059570
19MP0001819_abnormal_immune_cell2.34529549
20MP0000716_abnormal_immune_system2.30180798
21MP0002420_abnormal_adaptive_immunity2.29871014
22MP0005000_abnormal_immune_tolerance2.29837614
23MP0005464_abnormal_platelet_physiology2.28344035
24MP0002722_abnormal_immune_system2.18335698
25MP0000689_abnormal_spleen_morphology2.16462921
26MP0002452_abnormal_antigen_presenting2.11367731
27MP0009278_abnormal_bone_marrow2.07407763
28MP0002723_abnormal_immune_serum2.04379330
29MP0003436_decreased_susceptibility_to2.03002916
30MP0003303_peritoneal_inflammation1.99516820
31MP0001853_heart_inflammation1.98575613
32MP0006082_CNS_inflammation1.98084258
33MP0005377_hearing/vestibular/ear_phenot1.95516189
34MP0003878_abnormal_ear_physiology1.95516189
35MP0002933_joint_inflammation1.93852420
36MP0002429_abnormal_blood_cell1.92525511
37MP0005409_darkened_coat_color1.87009171
38MP0008057_abnormal_DNA_replication1.85447008
39MP0002148_abnormal_hypersensitivity_rea1.80023246
40MP0003866_abnormal_defecation1.78745762
41MP0002163_abnormal_gland_morphology1.78439917
42MP0009333_abnormal_splenocyte_physiolog1.69069405
43MP0000383_abnormal_hair_follicle1.62870250
44MP0002405_respiratory_system_inflammati1.62067892
45MP0010155_abnormal_intestine_physiology1.61792544
46MP0005025_abnormal_response_to1.59882988
47MP0000465_gastrointestinal_hemorrhage1.58733654
48MP0003786_premature_aging1.57819857
49MP0003724_increased_susceptibility_to1.57415100
50MP0002419_abnormal_innate_immunity1.56520929
51MP0001485_abnormal_pinna_reflex1.55621725
52MP0002102_abnormal_ear_morphology1.49505567
53MP0000490_abnormal_crypts_of1.47919007
54MP0008058_abnormal_DNA_repair1.47750312
55MP0010678_abnormal_skin_adnexa1.43566343
56MP0002138_abnormal_hepatobiliary_system1.38830721
57MP0000372_irregular_coat_pigmentation1.33367513
58MP0003045_fibrosis1.32353934
59MP0003077_abnormal_cell_cycle1.32150334
60MP0001905_abnormal_dopamine_level1.30200481
61MP0005387_immune_system_phenotype1.28657181
62MP0001790_abnormal_immune_system1.28657181
63MP0003787_abnormal_imprinting1.28273994
64MP0002277_abnormal_respiratory_mucosa1.27142100
65MP0009785_altered_susceptibility_to1.25554743
66MP0010234_abnormal_vibrissa_follicle1.22579880
67MP0004134_abnormal_chest_morphology1.22121586
68MP0002877_abnormal_melanocyte_morpholog1.20557016
69MP0010307_abnormal_tumor_latency1.18497135
70MP0005645_abnormal_hypothalamus_physiol1.16520709
71MP0001845_abnormal_inflammatory_respons1.16210834
72MP0001919_abnormal_reproductive_system1.16097234
73MP0004147_increased_porphyrin_level1.16094295
74MP0002095_abnormal_skin_pigmentation1.12975552
75MP0009763_increased_sensitivity_to1.12602939
76MP0002009_preneoplasia1.11327459
77MP0004381_abnormal_hair_follicle1.11156434
78MP0002019_abnormal_tumor_incidence1.09859025
79MP0005220_abnormal_exocrine_pancreas1.08466112
80MP0006054_spinal_hemorrhage1.07546722
81MP0002909_abnormal_adrenal_gland1.04694590
82MP0004947_skin_inflammation1.04207324
83MP0003806_abnormal_nucleotide_metabolis1.03327241
84MP0003300_gastrointestinal_ulcer1.02876950
85MP0000858_altered_metastatic_potential1.02848383
86MP0003828_pulmonary_edema0.99331007
87MP0002693_abnormal_pancreas_physiology0.98913879
88MP0009840_abnormal_foam_cell0.98488685
89MP0008995_early_reproductive_senescence0.98289542
90MP0001348_abnormal_lacrimal_gland0.95755013
91MP0003137_abnormal_impulse_conducting0.95708109
92MP0002876_abnormal_thyroid_physiology0.93021718
93MP0003011_delayed_dark_adaptation0.92710643
94MP0004145_abnormal_muscle_electrophysio0.91469033
95MP0005379_endocrine/exocrine_gland_phen0.90896055
96MP0003075_altered_response_to0.90105794
97MP0001188_hyperpigmentation0.88064156
98MP0010386_abnormal_urinary_bladder0.86628416
99MP0008873_increased_physiological_sensi0.86115757
100MP0005310_abnormal_salivary_gland0.81151689
101MP0002638_abnormal_pupillary_reflex0.80902187
102MP0006072_abnormal_retinal_apoptosis0.80778542
103MP0001346_abnormal_lacrimal_gland0.80552478
104MP0009643_abnormal_urine_homeostasis0.78879199
105MP0005360_urolithiasis0.77941543
106MP0005075_abnormal_melanosome_morpholog0.77708141
107MP0000343_altered_response_to0.77544552
108MP0005166_decreased_susceptibility_to0.77388739
109MP0009764_decreased_sensitivity_to0.77236229
110MP0002132_abnormal_respiratory_system0.75354887
111MP0004957_abnormal_blastocyst_morpholog0.72578749
112MP0003111_abnormal_nucleus_morphology0.72371319
113MP0005174_abnormal_tail_pigmentation0.72261196
114MP0004742_abnormal_vestibular_system0.70793494
115MP0008469_abnormal_protein_level0.69775985
116MP0001243_abnormal_dermal_layer0.69383238
117MP0009379_abnormal_foot_pigmentation0.69227802
118MP0001661_extended_life_span0.67311984
119MP0008770_decreased_survivor_rate0.66001490
120MP0008872_abnormal_physiological_respon0.65788177
121MP0003943_abnormal_hepatobiliary_system0.65334381
122MP0002928_abnormal_bile_duct0.63822212
123MP0005389_reproductive_system_phenotype0.63765259
124MP0005636_abnormal_mineral_homeostasis0.63696966
125MP0002136_abnormal_kidney_physiology0.62467407
126MP0000920_abnormal_myelination0.62317969
127MP0001542_abnormal_bone_strength0.62243358
128MP0000609_abnormal_liver_physiology0.60886494
129MP0000249_abnormal_blood_vessel0.60074148
130MP0001533_abnormal_skeleton_physiology0.59657602
131MP0000427_abnormal_hair_cycle0.59210276
132MP0001984_abnormal_olfaction0.58736592
133MP0001666_abnormal_nutrient_absorption0.58266679
134MP0003448_altered_tumor_morphology0.57631485
135MP0002090_abnormal_vision0.56487143
136MP0000350_abnormal_cell_proliferation0.56067207
137MP0003690_abnormal_glial_cell0.55885573
138MP0001765_abnormal_ion_homeostasis0.55858097
139MP0005584_abnormal_enzyme/coenzyme_acti0.55775405
140MP0003567_abnormal_fetal_cardiomyocyte0.55503862
141MP0003693_abnormal_embryo_hatching0.55027744
142MP0008875_abnormal_xenobiotic_pharmacok0.54548073
143MP0001501_abnormal_sleep_pattern0.54086365
144MP0000598_abnormal_liver_morphology0.53142494
145MP0000477_abnormal_intestine_morphology0.52337067
146MP0009765_abnormal_xenobiotic_induced0.51919706
147MP0002733_abnormal_thermal_nociception0.49929493
148MP0001915_intracranial_hemorrhage0.48843900
149MP0002075_abnormal_coat/hair_pigmentati0.48133120

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)6.51049101
2Abnormality of T cell number (HP:0011839)6.01840683
3Increased neuronal autofluorescent lipopigment (HP:0002074)4.87272746
4Recurrent viral infections (HP:0004429)4.82752544
5Thyroiditis (HP:0100646)4.75062320
6B lymphocytopenia (HP:0010976)4.52193371
7Abnormality of B cell number (HP:0010975)4.52193371
8Increased IgM level (HP:0003496)4.51998286
9Increased cerebral lipofuscin (HP:0011813)4.38453404
10Hypoplasia of the thymus (HP:0000778)4.33945999
11Autoimmune hemolytic anemia (HP:0001890)4.10582735
12Increased intramyocellular lipid droplets (HP:0012240)4.05694027
13Abnormality of the fingertips (HP:0001211)3.93861855
14Abnormality of T cells (HP:0002843)3.90890017
15IgG deficiency (HP:0004315)3.66896114
16Panhypogammaglobulinemia (HP:0003139)3.65429177
17Reticulocytopenia (HP:0001896)3.61626184
18Combined immunodeficiency (HP:0005387)3.56885205
19Volvulus (HP:0002580)3.55214467
20Loss of speech (HP:0002371)3.50403955
21Severe combined immunodeficiency (HP:0004430)3.48577630
22Amaurosis fugax (HP:0100576)3.46777408
23Recurrent fungal infections (HP:0002841)3.42682615
24Prolonged bleeding time (HP:0003010)3.41714192
25Chronic mucocutaneous candidiasis (HP:0002728)3.40457815
26Recurrent cutaneous fungal infections (HP:0011370)3.40457815
27Eosinophilia (HP:0001880)3.39529230
28Abnormal platelet volume (HP:0011876)3.37322918
29Meningitis (HP:0001287)3.35843159
30Increased muscle lipid content (HP:0009058)3.32955911
31Decreased activity of mitochondrial respiratory chain (HP:0008972)3.28640292
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.28640292
33Chronic otitis media (HP:0000389)3.20075690
34Papilledema (HP:0001085)3.06109545
35Papilloma (HP:0012740)3.03495314
36Verrucae (HP:0200043)3.03495314
37IgM deficiency (HP:0002850)2.99992667
38Hypoalbuminemia (HP:0003073)2.98622616
39Abnormal albumin level (HP:0012116)2.98622616
40Increased mean platelet volume (HP:0011877)2.96545835
41Gangrene (HP:0100758)2.96366056
42Aplastic anemia (HP:0001915)2.92709227
43Amyotrophic lateral sclerosis (HP:0007354)2.90458486
44Pulmonary infiltrates (HP:0002113)2.85446733
453-Methylglutaconic aciduria (HP:0003535)2.84292874
46Thrombocytosis (HP:0001894)2.80600918
47Agnosia (HP:0010524)2.71115758
48Abnormality of macrophages (HP:0004311)2.70387582
49Granulocytopenia (HP:0001913)2.68574233
50Mitochondrial inheritance (HP:0001427)2.66398489
51Renal Fanconi syndrome (HP:0001994)2.65503644
52Mucosal telangiectasiae (HP:0100579)2.64691750
53Joint swelling (HP:0001386)2.62717572
54Recurrent otitis media (HP:0000403)2.62149225
55Lymphoma (HP:0002665)2.60169003
56Increased hepatocellular lipid droplets (HP:0006565)2.60161851
57Elevated erythrocyte sedimentation rate (HP:0003565)2.58964022
58Ureteral stenosis (HP:0000071)2.58363060
59Chronic obstructive pulmonary disease (HP:0006510)2.57545175
60Obstructive lung disease (HP:0006536)2.57545175
61Cellulitis (HP:0100658)2.56407280
62Abnormal mitochondria in muscle tissue (HP:0008316)2.47280935
63Chest pain (HP:0100749)2.46659476
64Vasculitis (HP:0002633)2.45457034
65Ureteral obstruction (HP:0006000)2.45096341
66Abnormal delayed hypersensitivity skin test (HP:0002963)2.44905180
67Radial bowing (HP:0002986)2.43569721
68Bronchitis (HP:0012387)2.41655588
69Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41473434
70Abnormality of eosinophils (HP:0001879)2.38539343
71Recurrent skin infections (HP:0001581)2.36898336
72Myositis (HP:0100614)2.36812885
73Gingival bleeding (HP:0000225)2.31714735
74Leukocytosis (HP:0001974)2.31023902
75Keratoconjunctivitis sicca (HP:0001097)2.30208952
76Optic neuritis (HP:0100653)2.26832877
77Retrobulbar optic neuritis (HP:0100654)2.26832877
78Epistaxis (HP:0000421)2.25027619
79Subaortic stenosis (HP:0001682)2.24142256
80Abnormality of the left ventricular outflow tract (HP:0011103)2.24142256
81Impulsivity (HP:0100710)2.22800873
82Type I transferrin isoform profile (HP:0003642)2.22553615
83Arterial thrombosis (HP:0004420)2.22308099
84Acrocyanosis (HP:0001063)2.21213319
85Gastrointestinal infarctions (HP:0005244)2.20262213
86Acute necrotizing encephalopathy (HP:0006965)2.20081847
87Cutis marmorata (HP:0000965)2.19872610
88Abnormality of the pleura (HP:0002103)2.17176156
89Pancytopenia (HP:0001876)2.16870376
90Abnormality of T cell physiology (HP:0011840)2.15838102
91Asymmetry of the thorax (HP:0001555)2.14872399
92Abnormality of cells of the erythroid lineage (HP:0012130)2.14330496
93Ependymoma (HP:0002888)2.14301784
94Abnormality of the prostate (HP:0008775)2.14197921
95Agammaglobulinemia (HP:0004432)2.13006546
96Carpal bone hypoplasia (HP:0001498)2.12831215
97Abnormality of oral frenula (HP:0000190)2.11668114
98Lymphopenia (HP:0001888)2.11169276
99Encephalitis (HP:0002383)2.11089160
100Absent rod-and cone-mediated responses on ERG (HP:0007688)2.10995106
101Recurrent bronchitis (HP:0002837)2.09595047
102Pigmentary retinal degeneration (HP:0001146)2.08986185
103Acute myeloid leukemia (HP:0004808)2.08402663
104Hypergammaglobulinemia (HP:0010702)2.08180489
105Chronic diarrhea (HP:0002028)2.06076158
106Gastrointestinal inflammation (HP:0004386)2.06003389
107Hemiplegia (HP:0002301)2.05379851
108Ascites (HP:0001541)2.05322368
109Recurrent abscess formation (HP:0002722)2.04889140
110Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.04204462
111Lipid accumulation in hepatocytes (HP:0006561)2.03930312
112Hypoproteinemia (HP:0003075)2.03038004
113Autoimmune thrombocytopenia (HP:0001973)2.02483997
114Pallor (HP:0000980)2.01716085
115Keratoconjunctivitis (HP:0001096)2.00826111
116Cerebral palsy (HP:0100021)1.99535565
117Hemoptysis (HP:0002105)1.99468591
118Spastic paraparesis (HP:0002313)1.98571664
119Ankyloglossia (HP:0010296)1.98191995
120Acute hepatic failure (HP:0006554)1.98032857
121Aplasia/Hypoplasia of the thymus (HP:0010515)1.97964670
122Recurrent bacterial skin infections (HP:0005406)1.97743564
123Myelodysplasia (HP:0002863)1.97441497
124Stomatitis (HP:0010280)1.96206613
125Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.96106161
126Testicular atrophy (HP:0000029)1.96058498
127Inflammation of the large intestine (HP:0002037)1.94441395
128Severe visual impairment (HP:0001141)1.94155440
129Pulmonary embolism (HP:0002204)1.94137560
130Abnormality of cells of the lymphoid lineage (HP:0012140)1.93929290
131Petechiae (HP:0000967)1.93795215
132Orchitis (HP:0100796)1.91967370
133Abnormality of the alveolar ridges (HP:0006477)1.91843921
134Exertional dyspnea (HP:0002875)1.91200848
135Abnormality of the pericardium (HP:0001697)1.90337790
136Reduced antithrombin III activity (HP:0001976)1.88670941
137Basal cell carcinoma (HP:0002671)1.88644465
138Decreased electroretinogram (ERG) amplitude (HP:0000654)1.88542016
139Abnormality of midbrain morphology (HP:0002418)1.87373431
140Molar tooth sign on MRI (HP:0002419)1.87373431
141Abnormality of the thymus (HP:0000777)1.84424435
142Purpura (HP:0000979)1.83909984
143Polyneuropathy (HP:0001271)1.79656008
144Glomerulopathy (HP:0100820)1.78746618
145Macroorchidism (HP:0000053)1.78721105
146Cutaneous melanoma (HP:0012056)1.78679449
147Atonic seizures (HP:0010819)1.77792517
148Abnormality of male internal genitalia (HP:0000022)1.77004511
149Teleangiectasia of the skin (HP:0100585)1.76740127
150Arthropathy (HP:0003040)1.76189977
151Pseudobulbar signs (HP:0002200)1.74243253
152Sepsis (HP:0100806)1.72997406

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR6.31253576
2MAP4K15.04207484
3TLK14.06504751
4TXK3.95227289
5TSSK63.86038926
6BCKDK3.07644213
7GRK62.94711176
8EEF2K2.77009573
9TESK12.66870030
10FGFR22.57368103
11RPS6KB22.44191439
12MAP3K132.35912147
13MST42.27980838
14FRK2.12603144
15ADRBK22.06883216
16PKN21.97099106
17LIMK11.86426190
18ZAK1.76953250
19SYK1.75568031
20ITK1.73813331
21TAOK31.71027135
22CSK1.69117131
23FGFR31.68287780
24IRAK41.66492567
25MAP3K71.65418404
26STK41.65296685
27GRK71.63797845
28MAP3K101.61528287
29ZAP701.50350863
30CDC71.48773110
31LRRK21.46192603
32NEK21.43069384
33MAP3K141.39930346
34PIM11.36692083
35MYLK1.35759617
36TRPM71.35725593
37STK101.26154946
38VRK21.22989382
39BRD41.20083041
40CLK11.19368344
41TYRO31.17822266
42TAOK21.17438374
43TYK21.15934188
44CDK91.14791782
45CDK61.10509604
46TRIM281.08815549
47PRKCQ1.07815178
48MAPKAPK31.07322300
49HIPK21.02692664
50BTK0.99949997
51DAPK10.94755561
52EPHB10.94310549
53NEK10.90939083
54FGFR40.90787370
55MAP3K120.90057881
56UHMK10.88023139
57AURKB0.86899281
58LCK0.86000574
59HCK0.85954350
60PASK0.85474491
61TIE10.85425427
62PRKCH0.84282696
63MAP3K80.82813476
64TGFBR10.82620721
65TEC0.81908066
66ALK0.81876993
67IKBKE0.80579634
68JAK10.78905684
69JAK20.78227805
70LYN0.77820300
71PDK10.77161607
72CSF1R0.76479830
73FLT30.71907942
74MAP4K20.70834701
75ROCK10.69167100
76PKN10.68829686
77MAPKAPK50.67466285
78WNK40.67299021
79FES0.65725338
80NUAK10.65703492
81GRK10.64551013
82ATR0.63849176
83MAPK40.62338491
84TNK20.61383295
85RPS6KB10.59453916
86MATK0.58979791
87MAPK110.58409456
88ACVR1B0.57877902
89VRK10.57424852
90PIK3CA0.55744599
91SRPK10.55620999
92SCYL20.54683010
93CDK40.54417294
94BLK0.53722677
95BRSK20.53404512
96INSR0.52873120
97LMTK20.52646365
98PIK3CG0.52645910
99JAK30.52331056
100PTK60.51391374
101MAP2K30.50027762
102KIT0.49437953
103RIPK40.49058347
104PDGFRB0.48876596
105BUB10.47715358
106IGF1R0.47240522
107PDGFRA0.45011934
108MAP2K60.44411245
109RPS6KA50.43963510
110ADRBK10.43817484
111NTRK20.43172821
112INSRR0.43094720
113OBSCN0.42527893
114DYRK1B0.41071145
115PLK30.41020206
116IKBKB0.40862211
117MAPKAPK20.39527910
118EIF2AK30.38272330
119TAOK10.37109065
120TESK20.36561296
121PRKDC0.35954894
122ILK0.35950947
123MKNK20.35489272
124STK38L0.34768455
125CSNK1G30.34588663
126RPS6KL10.34070846
127RPS6KC10.34070846
128BCR0.33075144
129MAP3K110.33051337
130BMPR20.32783989
131TGFBR20.31604243
132FYN0.31377763
133CDK120.31240802
134ATM0.29808051
135PRKCA0.29557400
136MUSK0.25234075
137MAP3K50.24181645
138PRKACA0.23408178
139CAMKK20.22159541
140GRK50.20566404
141BMPR1B0.19844425
142TBK10.19744450
143CAMK2A0.19113939
144PAK10.18345238
145DAPK30.16980691
146MELK0.16409835
147ABL10.16220117
148CSNK2A10.14413239
149CSNK1A1L0.13846934
150SRC0.13643089
151ERBB30.13475409
152AURKA0.12891948
153CDK180.11985776

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034508.60216757
2Systemic lupus erythematosus_Homo sapiens_hsa053225.54305240
3Proteasome_Homo sapiens_hsa030503.84677786
4Graft-versus-host disease_Homo sapiens_hsa053323.67326025
5Autoimmune thyroid disease_Homo sapiens_hsa053203.41004308
6Alcoholism_Homo sapiens_hsa050343.17963620
7Primary immunodeficiency_Homo sapiens_hsa053403.17207472
8Allograft rejection_Homo sapiens_hsa053302.90550711
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.87701879
10Ribosome_Homo sapiens_hsa030102.58441391
11DNA replication_Homo sapiens_hsa030302.43979514
12Mismatch repair_Homo sapiens_hsa034302.42054214
13Fatty acid elongation_Homo sapiens_hsa000622.37533657
14Oxidative phosphorylation_Homo sapiens_hsa001902.36241660
15Type I diabetes mellitus_Homo sapiens_hsa049402.32183296
16Hematopoietic cell lineage_Homo sapiens_hsa046402.27733986
17Rheumatoid arthritis_Homo sapiens_hsa053232.23132217
18T cell receptor signaling pathway_Homo sapiens_hsa046602.09894634
19Viral carcinogenesis_Homo sapiens_hsa052032.08968531
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.05784868
21Salmonella infection_Homo sapiens_hsa051322.03339940
22Parkinsons disease_Homo sapiens_hsa050121.97760629
23Measles_Homo sapiens_hsa051621.76588109
24Antigen processing and presentation_Homo sapiens_hsa046121.67458885
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.65244997
26RNA polymerase_Homo sapiens_hsa030201.55040293
27B cell receptor signaling pathway_Homo sapiens_hsa046621.54024909
28Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.48577194
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.48437474
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.47142780
31Alzheimers disease_Homo sapiens_hsa050101.37215563
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36892065
33Fatty acid metabolism_Homo sapiens_hsa012121.35593379
34Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.32820214
35Leishmaniasis_Homo sapiens_hsa051401.31548665
36Leukocyte transendothelial migration_Homo sapiens_hsa046701.29100944
37Cell cycle_Homo sapiens_hsa041101.23524069
38Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.22514168
39Malaria_Homo sapiens_hsa051441.21726354
40Base excision repair_Homo sapiens_hsa034101.15371699
41NF-kappa B signaling pathway_Homo sapiens_hsa040641.13785476
42Cardiac muscle contraction_Homo sapiens_hsa042601.12651107
43Spliceosome_Homo sapiens_hsa030401.06380505
44Platelet activation_Homo sapiens_hsa046111.06165928
45MicroRNAs in cancer_Homo sapiens_hsa052061.03510775
46Huntingtons disease_Homo sapiens_hsa050161.02363301
47Protein export_Homo sapiens_hsa030601.01840489
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96675000
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94748893
50Toxoplasmosis_Homo sapiens_hsa051450.92809791
51Osteoclast differentiation_Homo sapiens_hsa043800.91807170
52Hepatitis B_Homo sapiens_hsa051610.89059778
53Chemokine signaling pathway_Homo sapiens_hsa040620.88285262
54Asthma_Homo sapiens_hsa053100.87386700
55Transcriptional misregulation in cancer_Homo sapiens_hsa052020.87083394
56Staphylococcus aureus infection_Homo sapiens_hsa051500.86048108
57Estrogen signaling pathway_Homo sapiens_hsa049150.83300336
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82791476
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81692673
60Chronic myeloid leukemia_Homo sapiens_hsa052200.81006489
61Non-small cell lung cancer_Homo sapiens_hsa052230.79980095
62Nitrogen metabolism_Homo sapiens_hsa009100.79374653
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.76607043
64Dorso-ventral axis formation_Homo sapiens_hsa043200.76378332
65HTLV-I infection_Homo sapiens_hsa051660.76103496
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74731589
67mTOR signaling pathway_Homo sapiens_hsa041500.74493767
68mRNA surveillance pathway_Homo sapiens_hsa030150.73992922
69Influenza A_Homo sapiens_hsa051640.73434003
70Acute myeloid leukemia_Homo sapiens_hsa052210.70489765
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70160633
72Long-term potentiation_Homo sapiens_hsa047200.65464705
73Notch signaling pathway_Homo sapiens_hsa043300.64819721
74RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64195083
75Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63515141
76Herpes simplex infection_Homo sapiens_hsa051680.63305693
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.61333802
78RNA degradation_Homo sapiens_hsa030180.60366935
79Legionellosis_Homo sapiens_hsa051340.58016359
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.57200636
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56927928
82Pentose phosphate pathway_Homo sapiens_hsa000300.52727440
83Epstein-Barr virus infection_Homo sapiens_hsa051690.52531042
84Pancreatic cancer_Homo sapiens_hsa052120.52273690
85Steroid hormone biosynthesis_Homo sapiens_hsa001400.52194929
86Toll-like receptor signaling pathway_Homo sapiens_hsa046200.51346304
87Apoptosis_Homo sapiens_hsa042100.47730847
88Phototransduction_Homo sapiens_hsa047440.46349677
89Peroxisome_Homo sapiens_hsa041460.46345605
90Pyrimidine metabolism_Homo sapiens_hsa002400.46075278
91TNF signaling pathway_Homo sapiens_hsa046680.43984553
92Butanoate metabolism_Homo sapiens_hsa006500.43825932
93Glioma_Homo sapiens_hsa052140.43585191
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.43276700
95Regulation of actin cytoskeleton_Homo sapiens_hsa048100.43244613
96Colorectal cancer_Homo sapiens_hsa052100.42194023
97Chemical carcinogenesis_Homo sapiens_hsa052040.41414692
98Linoleic acid metabolism_Homo sapiens_hsa005910.39960836
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38803172
100Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37887642
101Caffeine metabolism_Homo sapiens_hsa002320.37828045
102Fanconi anemia pathway_Homo sapiens_hsa034600.37786515
103Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37280130
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37098204
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34980506
106Small cell lung cancer_Homo sapiens_hsa052220.34113453
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33864201
108Purine metabolism_Homo sapiens_hsa002300.33700351
109Insulin resistance_Homo sapiens_hsa049310.33275197
110Collecting duct acid secretion_Homo sapiens_hsa049660.33154021
111Gastric acid secretion_Homo sapiens_hsa049710.32367379
112Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.32107783
113One carbon pool by folate_Homo sapiens_hsa006700.31942810
114African trypanosomiasis_Homo sapiens_hsa051430.31620971
115Selenocompound metabolism_Homo sapiens_hsa004500.31064398
116Lysine degradation_Homo sapiens_hsa003100.29079892
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28647379
118Retinol metabolism_Homo sapiens_hsa008300.27496301
119Olfactory transduction_Homo sapiens_hsa047400.25791531
120Prion diseases_Homo sapiens_hsa050200.24975890
121RNA transport_Homo sapiens_hsa030130.24131082
122Homologous recombination_Homo sapiens_hsa034400.23988579
123p53 signaling pathway_Homo sapiens_hsa041150.23320565
124Regulation of autophagy_Homo sapiens_hsa041400.22890797
125Shigellosis_Homo sapiens_hsa051310.22861972
126Viral myocarditis_Homo sapiens_hsa054160.22823520
127Rap1 signaling pathway_Homo sapiens_hsa040150.22292640
128Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.21471206
129Endocytosis_Homo sapiens_hsa041440.21180361
130FoxO signaling pathway_Homo sapiens_hsa040680.20775855
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19614647
132Glucagon signaling pathway_Homo sapiens_hsa049220.19560458
133Pertussis_Homo sapiens_hsa051330.19380919
134Propanoate metabolism_Homo sapiens_hsa006400.18858344
135Phagosome_Homo sapiens_hsa041450.18751515
136Aldosterone synthesis and secretion_Homo sapiens_hsa049250.18456915
137Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.18023818
138Proteoglycans in cancer_Homo sapiens_hsa052050.17514835
139Inositol phosphate metabolism_Homo sapiens_hsa005620.17323979
140HIF-1 signaling pathway_Homo sapiens_hsa040660.17215596
141Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.16827045
142Oocyte meiosis_Homo sapiens_hsa041140.16645901
143Prostate cancer_Homo sapiens_hsa052150.16405259
144AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.16312451
145Fatty acid degradation_Homo sapiens_hsa000710.15846581
146Thyroid cancer_Homo sapiens_hsa052160.15818348
147ABC transporters_Homo sapiens_hsa020100.15695852
148Arachidonic acid metabolism_Homo sapiens_hsa005900.15318828
149Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.15211061
150Renin secretion_Homo sapiens_hsa049240.14579967
151PPAR signaling pathway_Homo sapiens_hsa033200.14526499
152MAPK signaling pathway_Homo sapiens_hsa040100.14340696
153N-Glycan biosynthesis_Homo sapiens_hsa005100.13556450
154Thyroid hormone signaling pathway_Homo sapiens_hsa049190.13072164
155Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.12684895
156Drug metabolism - other enzymes_Homo sapiens_hsa009830.12675824
157Neurotrophin signaling pathway_Homo sapiens_hsa047220.11782722
158Tuberculosis_Homo sapiens_hsa051520.10589466
159Maturity onset diabetes of the young_Homo sapiens_hsa049500.08603812
160Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.06952530
161Metabolic pathways_Homo sapiens_hsa011000.06135210

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