TRGJ2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive T cell selection (GO:0043368)8.83010001
2V(D)J recombination (GO:0033151)8.49184704
3positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)8.40049246
4cellular hyperosmotic response (GO:0071474)7.47019082
5positive regulation of gamma-delta T cell activation (GO:0046645)7.37168365
6mitotic chromosome condensation (GO:0007076)7.21284515
7negative T cell selection (GO:0043383)7.07626192
8ribosomal small subunit assembly (GO:0000028)6.71136476
9regulation of gamma-delta T cell differentiation (GO:0045586)6.22595773
10regulation of histone H3-K9 methylation (GO:0051570)6.18051602
11Arp2/3 complex-mediated actin nucleation (GO:0034314)6.09432753
12regulation of regulatory T cell differentiation (GO:0045589)5.74484133
13antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.74130615
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.74130615
15eosinophil chemotaxis (GO:0048245)5.71205978
16DNA unwinding involved in DNA replication (GO:0006268)5.68897387
17positive regulation of natural killer cell mediated immunity (GO:0002717)5.64825854
18positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)5.60918211
19negative regulation by host of viral transcription (GO:0043922)5.50360984
20regulation of gamma-delta T cell activation (GO:0046643)5.46051539
21actin nucleation (GO:0045010)5.33637296
22negative regulation of viral genome replication (GO:0045071)5.31973899
23pyrimidine nucleoside catabolic process (GO:0046135)5.29180203
24T cell selection (GO:0045058)5.26616719
25regulation of activation of Janus kinase activity (GO:0010533)5.25701015
26viral transcription (GO:0019083)5.22824509
27eosinophil migration (GO:0072677)5.17708775
28negative regulation of T cell apoptotic process (GO:0070233)5.05497662
29translational termination (GO:0006415)4.96572641
30cytolysis (GO:0019835)4.87753310
31regulation of T cell tolerance induction (GO:0002664)4.84118968
32positive regulation of tolerance induction (GO:0002645)4.83384104
33regulation of natural killer cell mediated immunity (GO:0002715)4.82816671
34regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.82816671
35positive regulation of calcium-mediated signaling (GO:0050850)4.70334691
36positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.70245068
37ribosomal small subunit biogenesis (GO:0042274)4.69895176
38T cell receptor signaling pathway (GO:0050852)4.69579783
39antigen processing and presentation of endogenous antigen (GO:0019883)4.66273043
40regulation of chronic inflammatory response (GO:0002676)4.65038497
41macrophage chemotaxis (GO:0048246)4.64929222
42thymic T cell selection (GO:0045061)4.50777748
43establishment of integrated proviral latency (GO:0075713)4.49699688
44positive regulation of keratinocyte differentiation (GO:0045618)4.48044848
45positive regulation of interleukin-8 secretion (GO:2000484)4.40434748
46antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.39137650
47regulation of lymphocyte chemotaxis (GO:1901623)4.37646941
48positive regulation of histone H3-K4 methylation (GO:0051571)4.37618157
49positive regulation of translational initiation (GO:0045948)4.36651562
50T cell migration (GO:0072678)4.36571583
51cellular response to interleukin-15 (GO:0071350)4.27017596
52positive regulation of monocyte chemotaxis (GO:0090026)4.26937803
53regulation of T cell receptor signaling pathway (GO:0050856)4.25820401
54somatic cell DNA recombination (GO:0016444)4.24826659
55somatic diversification of immune receptors via germline recombination within a single locus (GO:0004.24826659
56translational elongation (GO:0006414)4.22736638
57regulation of leukocyte mediated cytotoxicity (GO:0001910)4.22667097
58antigen receptor-mediated signaling pathway (GO:0050851)4.17039367
59positive regulation of cell killing (GO:0031343)4.15451213
60negative regulation of histone methylation (GO:0031061)4.15060309
61regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.11413690
62negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.09022955
63negative regulation of cell killing (GO:0031342)4.09022955
64regulation of T cell chemotaxis (GO:0010819)4.07852613
65positive regulation of T cell chemotaxis (GO:0010820)4.07852613
66nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.05869132
67positive regulation of granulocyte differentiation (GO:0030854)4.05483673
68DNA ligation (GO:0006266)4.00205894
69monocyte chemotaxis (GO:0002548)3.97633248
70positive regulation of T cell apoptotic process (GO:0070234)3.97250922
71mitotic sister chromatid cohesion (GO:0007064)3.95356320
72cellular protein complex disassembly (GO:0043624)3.93767052
73natural killer cell differentiation (GO:0001779)3.93197761
74regulation of tolerance induction (GO:0002643)3.92619883
75mast cell activation (GO:0045576)3.90503898
76regulation of extracellular matrix disassembly (GO:0010715)3.90264547
77SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.87435842
78alternative mRNA splicing, via spliceosome (GO:0000380)3.87266805
79regulation of chemokine-mediated signaling pathway (GO:0070099)3.85046853
80positive regulation of B cell differentiation (GO:0045579)3.84484958
81cotranslational protein targeting to membrane (GO:0006613)3.81952701
82regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.81194328
83protein targeting to ER (GO:0045047)3.81147318
84DNA topological change (GO:0006265)3.80734608
85negative regulation of stress fiber assembly (GO:0051497)3.80300102
86somatic diversification of immune receptors (GO:0002200)3.77868309
87regulation of cell killing (GO:0031341)3.77245620
88germ cell migration (GO:0008354)3.73960497
89protein complex disassembly (GO:0043241)3.73865183
90cellular response to osmotic stress (GO:0071470)3.73156312
91T cell differentiation in thymus (GO:0033077)3.71628405
92chromosome condensation (GO:0030261)3.69252866
93establishment of protein localization to endoplasmic reticulum (GO:0072599)3.68641536
94regulation of RNA export from nucleus (GO:0046831)3.68137429
95T cell costimulation (GO:0031295)3.67134048
96regulation of mononuclear cell migration (GO:0071675)3.65946017
97regulation of viral genome replication (GO:0045069)3.65042124
98viral life cycle (GO:0019058)3.64829073
99positive regulation of T cell mediated cytotoxicity (GO:0001916)3.64640480
100B cell receptor signaling pathway (GO:0050853)3.60798848
101regulation of calcium-mediated signaling (GO:0050848)3.59032629
102activated T cell proliferation (GO:0050798)3.57952433
103lymphocyte costimulation (GO:0031294)3.57565142
104negative regulation of B cell proliferation (GO:0030889)3.54384504
105mast cell activation involved in immune response (GO:0002279)3.52980049
106mast cell degranulation (GO:0043303)3.52980049
107regulation of T cell apoptotic process (GO:0070232)3.49655473
108protein localization to endoplasmic reticulum (GO:0070972)3.49596934
109mucosal-associated lymphoid tissue development (GO:0048537)3.49287762
110Peyers patch development (GO:0048541)3.49287762
111response to interleukin-15 (GO:0070672)3.45810025
112regulation of interleukin-8 secretion (GO:2000482)3.43547349
113negative regulation of lymphocyte apoptotic process (GO:0070229)3.42104580
114antigen processing and presentation via MHC class Ib (GO:0002475)3.41670576
115positive regulation of histone methylation (GO:0031062)3.40515729
116negative regulation of RNA splicing (GO:0033119)3.40452091
117positive thymic T cell selection (GO:0045059)3.39421653
118regulation of histone methylation (GO:0031060)3.38659868
119regulation of extracellular matrix organization (GO:1903053)3.37238952
120translational initiation (GO:0006413)3.36948480
121regulation of T cell mediated cytotoxicity (GO:0001914)3.36078587
122regulation of macrophage chemotaxis (GO:0010758)3.35161763
123positive regulation of lymphocyte migration (GO:2000403)3.34578179
124negative regulation of viral process (GO:0048525)3.34391756
125macromolecular complex disassembly (GO:0032984)3.33917460
126chromatin assembly (GO:0031497)3.29490437
127negative regulation of phagocytosis (GO:0050765)3.29060463
128positive regulation by host of viral transcription (GO:0043923)3.28482133
129myelin maintenance (GO:0043217)3.27568270
130establishment of viral latency (GO:0019043)3.25699192
131GDP-mannose metabolic process (GO:0019673)3.25666077
132sister chromatid segregation (GO:0000819)3.22764211
133definitive hemopoiesis (GO:0060216)3.20655769
134regulation of nucleobase-containing compound transport (GO:0032239)3.20418538
135DNA duplex unwinding (GO:0032508)3.18468776
136nucleosome assembly (GO:0006334)3.18406852
137negative regulation of viral transcription (GO:0032897)3.17716984
138dendritic cell chemotaxis (GO:0002407)3.17633111
139negative regulation of calcium ion transport into cytosol (GO:0010523)3.16349740
140negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.16203803
141positive regulation of interleukin-4 production (GO:0032753)3.13755102
142sequestering of actin monomers (GO:0042989)3.13647798
143regulation of interleukin-2 biosynthetic process (GO:0045076)3.13608681
144DNA geometric change (GO:0032392)3.11761084
145ncRNA 3-end processing (GO:0043628)3.11346767
146regulation of B cell differentiation (GO:0045577)3.11298519
147nucleosome organization (GO:0034728)3.09658286
148regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.05616534
149pyrimidine-containing compound catabolic process (GO:0072529)3.00535062
150T cell differentiation (GO:0030217)3.00252386
151regulation of B cell receptor signaling pathway (GO:0050855)2.98828789
152DNA packaging (GO:0006323)2.98321443
153positive regulation of histone deacetylation (GO:0031065)2.97789466
154maturation of SSU-rRNA (GO:0030490)2.97175492
155regulation of histone H3-K4 methylation (GO:0051569)2.96953889
156negative thymic T cell selection (GO:0045060)2.96712977
157nuclear-transcribed mRNA catabolic process (GO:0000956)2.94322511
158positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.92806649
159T cell homeostasis (GO:0043029)2.92792318
160positive regulation of lamellipodium assembly (GO:0010592)2.92394204
161DNA replication-dependent nucleosome organization (GO:0034723)2.92250891
162DNA replication-dependent nucleosome assembly (GO:0006335)2.92250891
163T cell lineage commitment (GO:0002360)2.91234833
164adaptation of signaling pathway (GO:0023058)2.91092991
165antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.89906028
166positive regulation of lymphocyte apoptotic process (GO:0070230)2.89789600
167response to interferon-beta (GO:0035456)2.87087920
168positive regulation of lymphocyte mediated immunity (GO:0002708)2.86947156
169negative regulation of B cell activation (GO:0050869)2.86603026
170mRNA catabolic process (GO:0006402)2.86266830
171T cell apoptotic process (GO:0070231)2.84480262
172iron-sulfur cluster assembly (GO:0016226)2.84223779
173metallo-sulfur cluster assembly (GO:0031163)2.84223779
174modulation by host of viral transcription (GO:0043921)2.80765250
175modulation by host of symbiont transcription (GO:0052472)2.80765250
176negative regulation of actin filament bundle assembly (GO:0032232)2.79555764
177DNA demethylation (GO:0080111)2.79267607
178cytidine deamination (GO:0009972)12.4576619
179cytidine metabolic process (GO:0046087)12.4576619
180cytidine catabolic process (GO:0006216)12.4576619
181pyrimidine ribonucleoside catabolic process (GO:0046133)11.0371377
182DNA deamination (GO:0045006)10.4096208

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.69944043
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse5.13202055
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.30513180
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.89674435
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.84010093
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.40220274
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.08462070
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.94461932
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.92738318
10MYC_22102868_ChIP-Seq_BL_Human2.85074209
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.84401380
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.74551529
13RUNX_20019798_ChIP-Seq_JUKART_Human2.29192969
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.12339437
15FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse15.1873452
16CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.91649862
17TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91324130
18UTX_26944678_Chip-Seq_JUKART_Human1.84877118
19IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.84702524
20MYB_26560356_Chip-Seq_TH2_Human1.79927083
21NOTCH1_21737748_ChIP-Seq_TLL_Human1.72715882
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.70979021
23VDR_21846776_ChIP-Seq_THP-1_Human1.68305793
24SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.67551011
25KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66685737
26GATA3_26560356_Chip-Seq_TH2_Human1.65457256
27MAF_26560356_Chip-Seq_TH1_Human1.64098040
28VDR_22108803_ChIP-Seq_LS180_Human1.56888230
29TCF7_22412390_ChIP-Seq_EML_Mouse1.56570027
30IRF8_22096565_ChIP-ChIP_GC-B_Human1.55782321
31SCL_19346495_ChIP-Seq_HPC-7_Human1.55195408
32EGR1_23403033_ChIP-Seq_LIVER_Mouse1.53610065
33MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.48791057
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.48027281
35TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.46823883
36RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.46442210
37GATA1_22025678_ChIP-Seq_K562_Human1.44727821
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.44364518
39GATA3_27048872_Chip-Seq_THYMUS_Human1.42785121
40STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42629259
41HTT_18923047_ChIP-ChIP_STHdh_Human1.41683307
42PCGF2_27294783_Chip-Seq_NPCs_Mouse1.37987255
43RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.36509595
44GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36427291
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33783515
46STAT4_19710469_ChIP-ChIP_TH1__Mouse1.33416976
47MYB_21317192_ChIP-Seq_ERMYB_Mouse1.32458544
48VDR_24763502_ChIP-Seq_THP-1_Human1.32256361
49MYB_26560356_Chip-Seq_TH1_Human1.32135071
50KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.28651379
51EST1_17652178_ChIP-ChIP_JURKAT_Human1.28141440
52E2F1_21310950_ChIP-Seq_MCF-7_Human1.27832788
53GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.27242213
54PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.25903429
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25030643
56KDM2B_26808549_Chip-Seq_DND41_Human1.23110868
57BCL6_27268052_Chip-Seq_Bcells_Human1.21594605
58EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.20694508
59CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.19410896
60MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.19345277
61BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17949555
62EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.17575352
63LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17014276
64KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.15908268
65SMAD_19615063_ChIP-ChIP_OVARY_Human1.15581424
66TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.15213367
67IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.14046456
68FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12751897
69GABP_17652178_ChIP-ChIP_JURKAT_Human1.11633916
70MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.11357299
71E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06773125
72SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.06645185
73MYC_18555785_ChIP-Seq_MESCs_Mouse1.06611372
74BP1_19119308_ChIP-ChIP_Hs578T_Human1.04996513
75RUNX1_22412390_ChIP-Seq_EML_Mouse1.04291679
76FLI1_27457419_Chip-Seq_LIVER_Mouse1.03165512
77MYC_19079543_ChIP-ChIP_MESCs_Mouse1.02944830
78CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01873931
79NFE2_27457419_Chip-Seq_LIVER_Mouse1.01654415
80STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00788516
81TP53_22573176_ChIP-Seq_HFKS_Human1.00390684
82TAF2_19829295_ChIP-Seq_ESCs_Human0.99446890
83ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97760950
84SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.97524253
85NANOG_20526341_ChIP-Seq_ESCs_Human0.97442578
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.96515310
87PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96392756
88RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94553762
89JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.94202921
90MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.93997220
91HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91192258
92HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.91010246
93YY1_22570637_ChIP-Seq_MALME-3M_Human0.90735038
94CTCF_20526341_ChIP-Seq_ESCs_Human0.90657267
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90424428
96GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90103731
97KDM2B_26808549_Chip-Seq_JURKAT_Human0.89652143
98RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89222513
99RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88698240
100GATA3_26560356_Chip-Seq_TH1_Human0.88440826
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88295734
102SUZ12_27294783_Chip-Seq_NPCs_Mouse0.87883257
103SPI1_23127762_ChIP-Seq_K562_Human0.87659502
104GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.87617820
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87430132
106ELK1_19687146_ChIP-ChIP_HELA_Human0.86981759
107CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86756650
108KDM2B_26808549_Chip-Seq_SUP-B15_Human0.86563083
109ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.86185605
110MAF_26560356_Chip-Seq_TH2_Human0.85381691
111GATA2_22383799_ChIP-Seq_G1ME_Mouse0.84929481
112SOX2_19829295_ChIP-Seq_ESCs_Human0.84314738
113NANOG_19829295_ChIP-Seq_ESCs_Human0.84314738
114SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83169771
115SA1_27219007_Chip-Seq_Bcells_Human0.82948864
116P300_27268052_Chip-Seq_Bcells_Human0.82923619
117ETS1_22383799_ChIP-Seq_G1ME_Mouse0.82652803
118FOXA1_27270436_Chip-Seq_PROSTATE_Human0.82153662
119FOXA1_25329375_ChIP-Seq_VCAP_Human0.82153662
120CIITA_25753668_ChIP-Seq_RAJI_Human0.81388937
121EZH2_27294783_Chip-Seq_NPCs_Mouse0.81120693
122AR_20517297_ChIP-Seq_VCAP_Human0.80699957
123EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.80302253
124STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.80272843
125BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.80180327
126TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.79910193
127FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.79885754
128GATA6_21074721_ChIP-Seq_CACO-2_Human0.79061066
129NELFA_20434984_ChIP-Seq_ESCs_Mouse0.78755264
130AR_21572438_ChIP-Seq_LNCaP_Human0.78147137
131KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.78093288
132SOX2_16153702_ChIP-ChIP_HESCs_Human0.77976743
133MYC_19030024_ChIP-ChIP_MESCs_Mouse0.77585823
134TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77375824
135ELF1_20517297_ChIP-Seq_JURKAT_Human0.77210344
136NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.76838751
137AR_21909140_ChIP-Seq_LNCAP_Human0.75846670
138ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.75106244
139SOX2_18555785_ChIP-Seq_MESCs_Mouse0.74987014
140FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74107405
141GATA3_21878914_ChIP-Seq_MCF-7_Human0.73178506
142HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.72641616
143CLOCK_20551151_ChIP-Seq_293T_Human0.72607261
144ERA_21632823_ChIP-Seq_H3396_Human0.72405516
145AUTS2_25519132_ChIP-Seq_293T-REX_Human0.71960055
146EZH2_22144423_ChIP-Seq_EOC_Human0.71396284
147SRY_22984422_ChIP-ChIP_TESTIS_Rat0.70771924
148ZNF263_19887448_ChIP-Seq_K562_Human0.70509639
149POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.70484833
150VDR_23849224_ChIP-Seq_CD4+_Human0.70362612
151FOXH1_21741376_ChIP-Seq_EPCs_Human0.70291001
152RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.70277958
153VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.68349685
154ESR1_15608294_ChIP-ChIP_MCF-7_Human0.68040728
155KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.64837305
156XRN2_22483619_ChIP-Seq_HELA_Human0.64333560
157SPI1_23547873_ChIP-Seq_NB4_Human0.63295487
158MYC_18940864_ChIP-ChIP_HL60_Human0.63067759
159TP63_19390658_ChIP-ChIP_HaCaT_Human0.61967935
160GATA1_19941826_ChIP-Seq_K562_Human0.59935322
161NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.59714133
162IRF8_21731497_ChIP-ChIP_J774_Mouse0.59319455
163NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.58962496
164GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.58226551
165CHD1_26751641_Chip-Seq_LNCaP_Human0.57275218
166IRF8_27001747_Chip-Seq_BMDM_Mouse0.56114932

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000685_abnormal_immune_system4.60428390
2MP0003763_abnormal_thymus_physiology4.12226823
3MP0010352_gastrointestinal_tract_polyps4.03758406
4MP0000703_abnormal_thymus_morphology3.62991722
5MP0002396_abnormal_hematopoietic_system3.54322983
6MP0002166_altered_tumor_susceptibility3.02053797
7MP0002398_abnormal_bone_marrow2.92120363
8MP0006082_CNS_inflammation2.91563032
9MP0010234_abnormal_vibrissa_follicle2.90447591
10MP0010094_abnormal_chromosome_stability2.81097002
11MP0008007_abnormal_cellular_replicative2.80826526
12MP0005409_darkened_coat_color2.76131100
13MP0009278_abnormal_bone_marrow2.66215999
14MP0004808_abnormal_hematopoietic_stem2.57193636
15MP0002722_abnormal_immune_system2.38709626
16MP0001800_abnormal_humoral_immune2.29559716
17MP0000689_abnormal_spleen_morphology2.28213106
18MP0000716_abnormal_immune_system2.27541402
19MP0002006_tumorigenesis2.21712003
20MP0001545_abnormal_hematopoietic_system2.05807153
21MP0005397_hematopoietic_system_phenotyp2.05807153
22MP0002420_abnormal_adaptive_immunity1.96396178
23MP0003878_abnormal_ear_physiology1.95516189
24MP0005377_hearing/vestibular/ear_phenot1.95516189
25MP0002933_joint_inflammation1.93852420
26MP0005671_abnormal_response_to1.93527038
27MP0001819_abnormal_immune_cell1.92272136
28MP0002429_abnormal_blood_cell1.87762872
29MP0005000_abnormal_immune_tolerance1.82563874
30MP0002163_abnormal_gland_morphology1.78439917
31MP0008057_abnormal_DNA_replication1.78264921
32MP0002452_abnormal_antigen_presenting1.74849925
33MP0001835_abnormal_antigen_presentation1.74721501
34MP0010307_abnormal_tumor_latency1.71110106
35MP0003300_gastrointestinal_ulcer1.68662689
36MP0002723_abnormal_immune_serum1.68602532
37MP0010678_abnormal_skin_adnexa1.68414417
38MP0003077_abnormal_cell_cycle1.66496704
39MP0001853_heart_inflammation1.66221295
40MP0003786_premature_aging1.57819857
41MP0001485_abnormal_pinna_reflex1.55621725
42MP0006054_spinal_hemorrhage1.51383997
43MP0004947_skin_inflammation1.50468421
44MP0002102_abnormal_ear_morphology1.49505567
45MP0003436_decreased_susceptibility_to1.48775036
46MP0010155_abnormal_intestine_physiology1.47895530
47MP0005360_urolithiasis1.45877136
48MP0002405_respiratory_system_inflammati1.44106196
49MP0008058_abnormal_DNA_repair1.41156199
50MP0002138_abnormal_hepatobiliary_system1.38830721
51MP0004381_abnormal_hair_follicle1.38621148
52MP0005310_abnormal_salivary_gland1.37453545
53MP0003303_peritoneal_inflammation1.37270595
54MP0009333_abnormal_splenocyte_physiolog1.36431034
55MP0000372_irregular_coat_pigmentation1.33367513
56MP0003045_fibrosis1.32353934
57MP0000383_abnormal_hair_follicle1.31341473
58MP0008877_abnormal_DNA_methylation1.30490205
59MP0001905_abnormal_dopamine_level1.30200481
60MP0002277_abnormal_respiratory_mucosa1.27142100
61MP0000490_abnormal_crypts_of1.24295928
62MP0004957_abnormal_blastocyst_morpholog1.22121949
63MP0004134_abnormal_chest_morphology1.22121586
64MP0004147_increased_porphyrin_level1.21531773
65MP0008469_abnormal_protein_level1.20060164
66MP0003866_abnormal_defecation1.18912686
67MP0005645_abnormal_hypothalamus_physiol1.16520709
68MP0001919_abnormal_reproductive_system1.16097234
69MP0002019_abnormal_tumor_incidence1.14498498
70MP0009763_increased_sensitivity_to1.12602939
71MP0000465_gastrointestinal_hemorrhage1.11861386
72MP0005464_abnormal_platelet_physiology1.11454592
73MP0001661_extended_life_span1.10794210
74MP0005025_abnormal_response_to1.07959494
75MP0002909_abnormal_adrenal_gland1.04694590
76MP0003693_abnormal_embryo_hatching1.04571250
77MP0003806_abnormal_nucleotide_metabolis1.03327241
78MP0004130_abnormal_muscle_cell1.03173377
79MP0005220_abnormal_exocrine_pancreas1.02255968
80MP0000350_abnormal_cell_proliferation1.01202759
81MP0000427_abnormal_hair_cycle1.00069334
82MP0000013_abnormal_adipose_tissue0.99364095
83MP0002693_abnormal_pancreas_physiology0.98913879
84MP0008995_early_reproductive_senescence0.98289542
85MP0001790_abnormal_immune_system0.96363776
86MP0005387_immune_system_phenotype0.96363776
87MP0003137_abnormal_impulse_conducting0.95708109
88MP0002419_abnormal_innate_immunity0.94399535
89MP0002876_abnormal_thyroid_physiology0.93021718
90MP0001845_abnormal_inflammatory_respons0.92852295
91MP0003011_delayed_dark_adaptation0.92710643
92MP0003828_pulmonary_edema0.92112727
93MP0004145_abnormal_muscle_electrophysio0.91469033
94MP0005379_endocrine/exocrine_gland_phen0.90896055
95MP0009672_abnormal_birth_weight0.89540296
96MP0000858_altered_metastatic_potential0.88767470
97MP0001188_hyperpigmentation0.88064156
98MP0003724_increased_susceptibility_to0.87871562
99MP0010386_abnormal_urinary_bladder0.86628416
100MP0002009_preneoplasia0.86444907
101MP0008873_increased_physiological_sensi0.86115757
102MP0001730_embryonic_growth_arrest0.85215913
103MP0000920_abnormal_myelination0.83085913
104MP0008961_abnormal_basal_metabolism0.82508991
105MP0003787_abnormal_imprinting0.81127482
106MP0002638_abnormal_pupillary_reflex0.80902187
107MP0006072_abnormal_retinal_apoptosis0.80778542
108MP0001346_abnormal_lacrimal_gland0.80552478
109MP0003075_altered_response_to0.80180028
110MP0009643_abnormal_urine_homeostasis0.78879199
111MP0005166_decreased_susceptibility_to0.77388739
112MP0009764_decreased_sensitivity_to0.77236229
113MP0003111_abnormal_nucleus_morphology0.75826167
114MP0002132_abnormal_respiratory_system0.75354887
115MP0008770_decreased_survivor_rate0.74661294
116MP0008875_abnormal_xenobiotic_pharmacok0.74489304
117MP0004233_abnormal_muscle_weight0.73811895
118MP0002148_abnormal_hypersensitivity_rea0.72298989
119MP0002877_abnormal_melanocyte_morpholog0.71839820
120MP0004742_abnormal_vestibular_system0.70793494
121MP0001243_abnormal_dermal_layer0.69383238
122MP0009379_abnormal_foot_pigmentation0.69227802
123MP0009840_abnormal_foam_cell0.66029079
124MP0008872_abnormal_physiological_respon0.65788177
125MP0000462_abnormal_digestive_system0.65670720
126MP0008874_decreased_physiological_sensi0.64392784
127MP0005389_reproductive_system_phenotype0.63765259
128MP0005636_abnormal_mineral_homeostasis0.63696966
129MP0000003_abnormal_adipose_tissue0.63473971
130MP0000609_abnormal_liver_physiology0.62845813
131MP0002136_abnormal_kidney_physiology0.62467407
132MP0009785_altered_susceptibility_to0.62406274
133MP0001542_abnormal_bone_strength0.62243358
134MP0003448_altered_tumor_morphology0.61811791
135MP0000377_abnormal_hair_follicle0.61781042
136MP0000313_abnormal_cell_death0.61006241
137MP0001873_stomach_inflammation0.60245374
138MP0005076_abnormal_cell_differentiation0.59510490
139MP0001984_abnormal_olfaction0.58736592
140MP0002139_abnormal_hepatobiliary_system0.57716720
141MP0001765_abnormal_ion_homeostasis0.55858097
142MP0003121_genomic_imprinting0.55700599
143MP0002928_abnormal_bile_duct0.55527032
144MP0001533_abnormal_skeleton_physiology0.55464411
145MP0005647_abnormal_sex_gland0.55082356
146MP0002095_abnormal_skin_pigmentation0.54387869
147MP0009765_abnormal_xenobiotic_induced0.54330017
148MP0001501_abnormal_sleep_pattern0.54086365
149MP0001784_abnormal_fluid_regulation0.53482481
150MP0001177_atelectasis0.52077555
151MP0005023_abnormal_wound_healing0.52030246
152MP0004197_abnormal_fetal_growth/weight/0.52008754
153MP0005075_abnormal_melanosome_morpholog0.51957925
154MP0002086_abnormal_extraembryonic_tissu0.51887911
155MP0000477_abnormal_intestine_morphology0.51871308
156MP0000598_abnormal_liver_morphology0.51625204
157MP0001915_intracranial_hemorrhage0.50467454
158MP0005584_abnormal_enzyme/coenzyme_acti0.50411305
159MP0002733_abnormal_thermal_nociception0.49929493

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)7.29157751
2Abnormality of T cell number (HP:0011839)6.77108687
3Thyroiditis (HP:0100646)6.50920911
4B lymphocytopenia (HP:0010976)6.10279236
5Abnormality of B cell number (HP:0010975)6.10279236
6Hypoplasia of the thymus (HP:0000778)5.52386870
7Autoimmune hemolytic anemia (HP:0001890)5.48610791
8Recurrent viral infections (HP:0004429)5.16085305
9Aplastic anemia (HP:0001915)5.12450517
10Papilloma (HP:0012740)4.85781195
11Verrucae (HP:0200043)4.85781195
12Panhypogammaglobulinemia (HP:0003139)4.67192180
13Increased IgM level (HP:0003496)4.51998286
14Severe combined immunodeficiency (HP:0004430)4.35217990
15Abnormality of T cells (HP:0002843)4.27654084
16Eosinophilia (HP:0001880)4.08378459
17Increased intramyocellular lipid droplets (HP:0012240)4.05694027
18Reticulocytopenia (HP:0001896)4.01577436
19IgG deficiency (HP:0004315)3.94212990
20Combined immunodeficiency (HP:0005387)3.91674656
21Chronic otitis media (HP:0000389)3.90779221
22Chronic diarrhea (HP:0002028)3.81906991
23Abnormal delayed hypersensitivity skin test (HP:0002963)3.57910668
24Recurrent fungal infections (HP:0002841)3.55859760
25Cellulitis (HP:0100658)3.41289088
26Agammaglobulinemia (HP:0004432)3.41272784
27Increased muscle lipid content (HP:0009058)3.32955911
28Decreased activity of mitochondrial respiratory chain (HP:0008972)3.28640292
29Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.28640292
30Abnormality of the prostate (HP:0008775)3.27004663
31Papilledema (HP:0001085)3.23087490
32Encephalitis (HP:0002383)3.22234561
33Granulocytopenia (HP:0001913)3.19713870
34Cutaneous melanoma (HP:0012056)3.15056436
35Retrobulbar optic neuritis (HP:0100654)3.11000045
36Optic neuritis (HP:0100653)3.11000045
37Volvulus (HP:0002580)3.05653783
38Hypoalbuminemia (HP:0003073)2.98622616
39Abnormal albumin level (HP:0012116)2.98622616
40Gangrene (HP:0100758)2.96366056
41Abnormality of eosinophils (HP:0001879)2.93428373
42Recurrent bronchitis (HP:0002837)2.91416803
43Amyotrophic lateral sclerosis (HP:0007354)2.90458486
44Meningitis (HP:0001287)2.86529420
45Pulmonary infiltrates (HP:0002113)2.85446733
463-Methylglutaconic aciduria (HP:0003535)2.84292874
47Asymmetry of the thorax (HP:0001555)2.81508195
48Keratoconjunctivitis (HP:0001096)2.74631327
49Obstructive lung disease (HP:0006536)2.71779848
50Chronic obstructive pulmonary disease (HP:0006510)2.71779848
51Abnormality of macrophages (HP:0004311)2.70387582
52Abnormality of oral frenula (HP:0000190)2.69898295
53Ankyloglossia (HP:0010296)2.68833334
54Abnormality of cells of the erythroid lineage (HP:0012130)2.67978782
55Vasculitis (HP:0002633)2.67639787
56Mitochondrial inheritance (HP:0001427)2.66398489
57Renal Fanconi syndrome (HP:0001994)2.65503644
58Abnormality of the fingertips (HP:0001211)2.64737586
59Joint swelling (HP:0001386)2.62717572
60Recurrent otitis media (HP:0000403)2.62149225
61Increased hepatocellular lipid droplets (HP:0006565)2.60161851
62Abnormality of the pleura (HP:0002103)2.58925797
63Ureteral stenosis (HP:0000071)2.58363060
64Hemoptysis (HP:0002105)2.57351144
65Keratoconjunctivitis sicca (HP:0001097)2.55963407
66Macroorchidism (HP:0000053)2.54985047
67Orchitis (HP:0100796)2.54103055
68Bicuspid aortic valve (HP:0001647)2.53037623
69Myositis (HP:0100614)2.52437565
70Abnormality of the thymus (HP:0000777)2.51690183
71Cutis marmorata (HP:0000965)2.49402265
72Hypoproteinemia (HP:0003075)2.49230823
73Abnormal mitochondria in muscle tissue (HP:0008316)2.47280935
74Chest pain (HP:0100749)2.46659476
75Ureteral obstruction (HP:0006000)2.45096341
76Acute lymphatic leukemia (HP:0006721)2.44548089
77IgM deficiency (HP:0002850)2.44096347
78Radial bowing (HP:0002986)2.43569721
79Bronchitis (HP:0012387)2.41655588
80Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41473434
81Abnormality of T cell physiology (HP:0011840)2.40455526
82Recurrent skin infections (HP:0001581)2.36898336
83Macrocytic anemia (HP:0001972)2.33911199
84Enlarged penis (HP:0000040)2.33887118
85Aplasia/Hypoplasia of the thymus (HP:0010515)2.32115876
86Autoimmune thrombocytopenia (HP:0001973)2.27764145
87Hematochezia (HP:0002573)2.26134804
88Lymphoma (HP:0002665)2.23528609
89Type I transferrin isoform profile (HP:0003642)2.22553615
90Leukocytosis (HP:0001974)2.22105773
91Gastrointestinal infarctions (HP:0005244)2.20262213
92Acute necrotizing encephalopathy (HP:0006965)2.20081847
93Pancytopenia (HP:0001876)2.16870376
94Abnormal hemoglobin (HP:0011902)2.14815766
95Acute myeloid leukemia (HP:0004808)2.13526934
96Chronic sinusitis (HP:0011109)2.12906006
97Carpal bone hypoplasia (HP:0001498)2.12831215
98Mucosal telangiectasiae (HP:0100579)2.12637852
99Spontaneous hematomas (HP:0007420)2.12209491
100Absent rod-and cone-mediated responses on ERG (HP:0007688)2.10995106
101Conjunctival hamartoma (HP:0100780)2.10667704
102Sepsis (HP:0100806)2.09103101
103Pigmentary retinal degeneration (HP:0001146)2.08986185
104Hypergammaglobulinemia (HP:0010702)2.08180489
105Hemiplegia (HP:0002301)2.05379851
106Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.04204462
107Lipid accumulation in hepatocytes (HP:0006561)2.03930312
108Conjunctival telangiectasia (HP:0000524)2.01625438
109Pseudobulbar signs (HP:0002200)1.99470246
110Lymphopenia (HP:0001888)1.98870218
111Vertebral arch anomaly (HP:0008438)1.98712954
112Spastic paraparesis (HP:0002313)1.98571664
113Abnormal number of erythroid precursors (HP:0012131)1.98164165
114Acute hepatic failure (HP:0006554)1.98032857
115Gastrointestinal inflammation (HP:0004386)1.96897919
116Stomatitis (HP:0010280)1.96206613
117Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.96106161
118Pancreatic islet-cell hyperplasia (HP:0004510)1.95670407
119IgA deficiency (HP:0002720)1.95164762
120Severe visual impairment (HP:0001141)1.94155440
121Neoplasm of the adrenal cortex (HP:0100641)1.93799865
122Osteomyelitis (HP:0002754)1.92619207
123Abnormality of the alveolar ridges (HP:0006477)1.91843921
124Abnormality of cells of the lymphoid lineage (HP:0012140)1.91681081
125Exertional dyspnea (HP:0002875)1.91200848
126Abnormality of the pericardium (HP:0001697)1.90337790
127Amaurosis fugax (HP:0100576)1.89523370
128Inflammation of the large intestine (HP:0002037)1.89168990
129Reduced antithrombin III activity (HP:0001976)1.88670941
130Thrombocytosis (HP:0001894)1.87393977
131Molar tooth sign on MRI (HP:0002419)1.87373431
132Abnormality of midbrain morphology (HP:0002418)1.87373431
133Recurrent bacterial skin infections (HP:0005406)1.85893202
134Pallor (HP:0000980)1.84204700
135Elevated erythrocyte sedimentation rate (HP:0003565)1.84031200
136Abnormal platelet volume (HP:0011876)1.83567760
137Abnormality of the intervertebral disk (HP:0005108)1.83125946
138Colitis (HP:0002583)1.82645836
139Abnormality of the pancreatic islet cells (HP:0006476)1.81565115
140Abnormality of endocrine pancreas physiology (HP:0012093)1.81565115
141Polyneuropathy (HP:0001271)1.79656008
142Arterial thrombosis (HP:0004420)1.79360889
143Glomerulopathy (HP:0100820)1.78746618
144Small epiphyses (HP:0010585)1.78207176
145Abnormality of male internal genitalia (HP:0000022)1.77004511
146Subaortic stenosis (HP:0001682)1.76368169
147Abnormality of the left ventricular outflow tract (HP:0011103)1.76368169
148Recurrent abscess formation (HP:0002722)1.75996350
149Hypochromic microcytic anemia (HP:0004840)1.75428858
150Aqueductal stenosis (HP:0002410)1.71009687
151Recurrent cutaneous fungal infections (HP:0011370)1.70061057
152Chronic mucocutaneous candidiasis (HP:0002728)1.70061057
153Basal cell carcinoma (HP:0002671)1.69957328
154Abnormality of reticulocytes (HP:0004312)1.69434637
155Erythroderma (HP:0001019)1.67009107
156Prolonged bleeding time (HP:0003010)1.65519008
157Obsessive-compulsive behavior (HP:0000722)1.61461188
158Angiofibromas (HP:0010615)1.60829234
159Adenoma sebaceum (HP:0009720)1.60829234
160Nasal polyposis (HP:0100582)1.60672892
161Increased IgE level (HP:0003212)1.59978771
162Broad palm (HP:0001169)1.58628243
163Abnormality of the columella (HP:0009929)1.58492151
164Pulmonary embolism (HP:0002204)1.58060447
165Teleangiectasia of the skin (HP:0100585)1.56746990
166Squamous cell carcinoma (HP:0002860)1.55836542
167Hypoplasia of the capital femoral epiphysis (HP:0003090)1.55066681
168Hypochromic anemia (HP:0001931)1.55014382
169Ulnar bowing (HP:0003031)1.54074349

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR6.31253576
2TLK14.46263262
3EEF2K4.29646402
4TSSK63.71386778
5GRK63.69743044
6FGFR23.59837786
7MAP3K103.42128001
8PKN23.18889662
9BCKDK3.07644213
10FRK2.99164757
11RPS6KB22.95036801
12TESK12.66870030
13MAP3K122.64021350
14MST42.50694392
15CDC72.27290068
16MAP4K12.22070260
17ADRBK22.06883216
18LRRK22.01526660
19BUB11.98752000
20ZAK1.97976198
21LIMK11.86426190
22FGFR31.82970438
23STK101.81379516
24CDK91.72673810
25TAOK31.71027135
26GRK71.63797845
27MAP3K71.55925372
28HIPK21.54597428
29STK41.53404217
30CLK11.45872413
31SCYL21.44825606
32ITK1.42771326
33MYLK1.35759617
34SYK1.34833754
35MAP2K61.29088075
36NEK21.23767920
37VRK21.22989382
38PIM11.22391860
39SIK21.19030196
40TYRO31.17822266
41FGFR41.17605503
42EPHB11.16570409
43CDK61.16258316
44VRK11.09751615
45TRIM281.08815549
46NTRK21.06475285
47FES1.01566572
48CSK1.00765586
49FLT31.00401354
50MAP3K80.97976428
51PTK60.97865974
52BTK0.97035185
53DAPK10.94755561
54TYK20.89394358
55PRKCH0.87954041
56TIE10.85425427
57PRKCQ0.85336375
58MAPK110.83802146
59MAPK40.81687650
60ZAP700.81566836
61TRIB30.80894710
62IKBKE0.80579634
63LCK0.78499938
64MAPKAPK50.78406905
65PAK20.77755117
66PDK10.77745017
67RIPK40.77374654
68RPS6KA50.76872842
69TESK20.75411869
70HCK0.74961996
71ALK0.74657123
72MAP3K130.73621915
73MAP4K20.70834701
74ROCK10.69167100
75RET0.68797518
76WNK40.67299021
77MAPK120.67052132
78PASK0.67033610
79CDK40.66561420
80MAP3K110.66494647
81CDK120.65377299
82ATR0.64676721
83GRK10.64551013
84RPS6KB10.62279098
85TRPM70.61199849
86PDGFRB0.60340335
87MARK20.59209489
88MAPKAPK30.58447147
89PIK3CA0.55744599
90JAK20.55485850
91SRPK10.55257811
92BLK0.53722677
93INSR0.52873120
94LMTK20.52646365
95PIK3CG0.52645910
96ILK0.51426219
97CSF1R0.51195945
98TXK0.50576960
99IKBKB0.49377935
100TGFBR10.48790225
101DAPK30.48140727
102AURKB0.47636192
103PKN10.47249223
104IGF1R0.47240522
105FGFR10.45415075
106UHMK10.44894390
107FYN0.44628761
108ADRBK10.43817484
109PLK30.43582573
110INSRR0.43094720
111ATM0.42832163
112OBSCN0.42527893
113CDK20.42313288
114DMPK0.41035196
115DYRK1B0.39767619
116MAPKAPK20.39527910
117EIF2AK30.38272330
118TEC0.37705599
119RPS6KL10.37516024
120RPS6KC10.37516024
121TGFBR20.36543556
122RAF10.36036458
123LYN0.36023371
124JAK30.35557948
125TNK20.35091036
126STK38L0.34768455
127CSNK1G30.34588663
128PRKDC0.34584381
129BCR0.33075144
130MATK0.32842854
131BMPR20.32783989
132MAPK140.31190658
133CSNK1D0.30836779
134PRKCA0.29557400
135CDK10.29419392
136RPS6KA60.29240002
137MAPK30.28887583
138CHEK10.28885066
139MAPK70.28404708
140NLK0.28356044
141MUSK0.25234075
142IRAK40.24815195
143KIT0.24620350
144MAP3K50.24181645
145PRKACA0.23408178
146CAMKK20.22159541
147GRK50.20566404
148BMPR1B0.19844425
149TBK10.19744450
150NUAK10.19211925
151CAMK2A0.19113939
152PAK10.18345238
153BRSK20.17657701
154MELK0.16409835
155ABL10.16220117
156CSNK2A10.14413239
157CSNK1A1L0.13846934
158SRC0.13643089
159ERBB30.13475409
160AURKA0.12891948
161CDK180.11985776

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034508.84786741
2Systemic lupus erythematosus_Homo sapiens_hsa053226.17476933
3Proteasome_Homo sapiens_hsa030503.84677786
4Graft-versus-host disease_Homo sapiens_hsa053323.67326025
5Alcoholism_Homo sapiens_hsa050343.64303395
6Primary immunodeficiency_Homo sapiens_hsa053403.55721174
7Autoimmune thyroid disease_Homo sapiens_hsa053203.41004308
8Allograft rejection_Homo sapiens_hsa053302.90550711
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.87701879
10Oxidative phosphorylation_Homo sapiens_hsa001902.36241660
11Ribosome_Homo sapiens_hsa030102.34278077
12Type I diabetes mellitus_Homo sapiens_hsa049402.32183296
13Rheumatoid arthritis_Homo sapiens_hsa053232.23132217
14Viral carcinogenesis_Homo sapiens_hsa052032.16626935
15Salmonella infection_Homo sapiens_hsa051322.03339940
16T cell receptor signaling pathway_Homo sapiens_hsa046602.01269246
17Parkinsons disease_Homo sapiens_hsa050121.97760629
18Hematopoietic cell lineage_Homo sapiens_hsa046401.88526022
19DNA replication_Homo sapiens_hsa030301.77730884
20Viral myocarditis_Homo sapiens_hsa054161.60754421
21RNA polymerase_Homo sapiens_hsa030201.55040293
22Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.48577194
23Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.48437474
24B cell receptor signaling pathway_Homo sapiens_hsa046621.43166179
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.42534852
26Shigellosis_Homo sapiens_hsa051311.40135752
27Alzheimers disease_Homo sapiens_hsa050101.37215563
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36892065
29Antigen processing and presentation_Homo sapiens_hsa046121.35018565
30Measles_Homo sapiens_hsa051621.34609894
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.30378011
32Leukocyte transendothelial migration_Homo sapiens_hsa046701.27997474
33Intestinal immune network for IgA production_Homo sapiens_hsa046721.27208624
34Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.26518556
35Malaria_Homo sapiens_hsa051441.21726354
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.21373854
37Chronic myeloid leukemia_Homo sapiens_hsa052201.19880236
38Non-small cell lung cancer_Homo sapiens_hsa052231.18789256
39Estrogen signaling pathway_Homo sapiens_hsa049151.15308300
40mTOR signaling pathway_Homo sapiens_hsa041501.12904861
41Cardiac muscle contraction_Homo sapiens_hsa042601.12651107
42MicroRNAs in cancer_Homo sapiens_hsa052061.11634457
43Mismatch repair_Homo sapiens_hsa034301.09299640
44Transcriptional misregulation in cancer_Homo sapiens_hsa052021.06392525
45Glioma_Homo sapiens_hsa052141.02572386
46Huntingtons disease_Homo sapiens_hsa050161.02363301
47Protein export_Homo sapiens_hsa030601.01840489
48Dorso-ventral axis formation_Homo sapiens_hsa043201.00006587
49Base excision repair_Homo sapiens_hsa034100.99591611
50Spliceosome_Homo sapiens_hsa030400.95905201
51Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94748893
52Acute myeloid leukemia_Homo sapiens_hsa052210.94211697
53Long-term potentiation_Homo sapiens_hsa047200.91581023
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88482059
55Asthma_Homo sapiens_hsa053100.87386700
56Staphylococcus aureus infection_Homo sapiens_hsa051500.86048108
57HTLV-I infection_Homo sapiens_hsa051660.84219847
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82791476
59Colorectal cancer_Homo sapiens_hsa052100.82391594
60Cell cycle_Homo sapiens_hsa041100.79537263
61Notch signaling pathway_Homo sapiens_hsa043300.78692570
62Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.78296359
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.76607043
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74731589
65Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73766844
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73740341
67NF-kappa B signaling pathway_Homo sapiens_hsa040640.73686633
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72893166
69Hepatitis B_Homo sapiens_hsa051610.71804601
70Osteoclast differentiation_Homo sapiens_hsa043800.71149514
71Pancreatic cancer_Homo sapiens_hsa052120.68776512
72Gastric acid secretion_Homo sapiens_hsa049710.68266462
73Prion diseases_Homo sapiens_hsa050200.64540441
74RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64195083
75One carbon pool by folate_Homo sapiens_hsa006700.60390975
76ErbB signaling pathway_Homo sapiens_hsa040120.60095968
77Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58286041
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58264967
79Leishmaniasis_Homo sapiens_hsa051400.57753034
80Pentose phosphate pathway_Homo sapiens_hsa000300.57664929
81Platelet activation_Homo sapiens_hsa046110.55979127
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55539988
83Toxoplasmosis_Homo sapiens_hsa051450.54891508
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54354778
85mRNA surveillance pathway_Homo sapiens_hsa030150.53251385
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.52194929
87Chemokine signaling pathway_Homo sapiens_hsa040620.52180135
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51948992
89Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50346899
90HIF-1 signaling pathway_Homo sapiens_hsa040660.49432166
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49031831
92Homologous recombination_Homo sapiens_hsa034400.48137961
93Apoptosis_Homo sapiens_hsa042100.47730847
94Type II diabetes mellitus_Homo sapiens_hsa049300.47246026
95Salivary secretion_Homo sapiens_hsa049700.46630230
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46539485
97Phototransduction_Homo sapiens_hsa047440.46349677
98Peroxisome_Homo sapiens_hsa041460.46345605
99Pyrimidine metabolism_Homo sapiens_hsa002400.46075278
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.44381603
101TNF signaling pathway_Homo sapiens_hsa046680.43984553
102Butanoate metabolism_Homo sapiens_hsa006500.43825932
103VEGF signaling pathway_Homo sapiens_hsa043700.43728765
104Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42943540
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42792543
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.42103418
107Proteoglycans in cancer_Homo sapiens_hsa052050.42022284
108FoxO signaling pathway_Homo sapiens_hsa040680.41781437
109Chemical carcinogenesis_Homo sapiens_hsa052040.41414692
110Lysine degradation_Homo sapiens_hsa003100.41029397
111Endometrial cancer_Homo sapiens_hsa052130.40042954
112Linoleic acid metabolism_Homo sapiens_hsa005910.39960836
113Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39889735
114Insulin resistance_Homo sapiens_hsa049310.39197708
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.39171131
116Renin secretion_Homo sapiens_hsa049240.38260090
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.38217103
118Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37887642
119Caffeine metabolism_Homo sapiens_hsa002320.37828045
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.37218978
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37098204
122Prostate cancer_Homo sapiens_hsa052150.35771397
123Small cell lung cancer_Homo sapiens_hsa052220.35490802
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33864201
125Purine metabolism_Homo sapiens_hsa002300.33700351
126Collecting duct acid secretion_Homo sapiens_hsa049660.33154021
127Legionellosis_Homo sapiens_hsa051340.32749850
128Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.32107783
129African trypanosomiasis_Homo sapiens_hsa051430.31620971
130Epstein-Barr virus infection_Homo sapiens_hsa051690.31588892
131Cholinergic synapse_Homo sapiens_hsa047250.31549002
132Selenocompound metabolism_Homo sapiens_hsa004500.31064398
133Oxytocin signaling pathway_Homo sapiens_hsa049210.30971418
134Arginine biosynthesis_Homo sapiens_hsa002200.30865861
135Herpes simplex infection_Homo sapiens_hsa051680.30058089
136Inositol phosphate metabolism_Homo sapiens_hsa005620.29817941
137Amphetamine addiction_Homo sapiens_hsa050310.29787133
138Thyroid hormone synthesis_Homo sapiens_hsa049180.28707379
139Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28647379
140Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.28404113
141Cyanoamino acid metabolism_Homo sapiens_hsa004600.27874689
142Retinol metabolism_Homo sapiens_hsa008300.27496301
143Nitrogen metabolism_Homo sapiens_hsa009100.26805106
144Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26601329
145Glucagon signaling pathway_Homo sapiens_hsa049220.26549990
146Dopaminergic synapse_Homo sapiens_hsa047280.26010912
147Pertussis_Homo sapiens_hsa051330.25959090
148Olfactory transduction_Homo sapiens_hsa047400.25791531
149Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.24479032
150Regulation of autophagy_Homo sapiens_hsa041400.22890797
151Influenza A_Homo sapiens_hsa051640.22796573
152Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.22537469
153Phospholipase D signaling pathway_Homo sapiens_hsa040720.21948613
154Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.20352886
155Endocytosis_Homo sapiens_hsa041440.20260767
156Neurotrophin signaling pathway_Homo sapiens_hsa047220.20020586
157Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19614647
158Propanoate metabolism_Homo sapiens_hsa006400.18858344
159Phagosome_Homo sapiens_hsa041450.18751515
160Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.18023818
161Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.16827045
162Arachidonic acid metabolism_Homo sapiens_hsa005900.15318828
163Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.15211061
164N-Glycan biosynthesis_Homo sapiens_hsa005100.13556450
165Fanconi anemia pathway_Homo sapiens_hsa034600.12343061
166Tuberculosis_Homo sapiens_hsa051520.10589466
167Maturity onset diabetes of the young_Homo sapiens_hsa049500.08603812
168Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.06952530
169Metabolic pathways_Homo sapiens_hsa011000.06135210

Most similar genes based on co-expression Upload to Enrichr

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