

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of thymocyte apoptotic process (GO:0070244) | 6.81399420 |
| 2 | V(D)J recombination (GO:0033151) | 5.12466969 |
| 3 | cellular response to ethanol (GO:0071361) | 4.96888895 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.91888205 |
| 5 | neutrophil activation involved in immune response (GO:0002283) | 4.85093754 |
| 6 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.70555594 |
| 7 | negative regulation of cell killing (GO:0031342) | 4.70555594 |
| 8 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.48927005 |
| 9 | regulation of thymocyte apoptotic process (GO:0070243) | 4.29396247 |
| 10 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.24575391 |
| 11 | T cell lineage commitment (GO:0002360) | 4.20669806 |
| 12 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.12616049 |
| 13 | immunoglobulin mediated immune response (GO:0016064) | 4.11945331 |
| 14 | negative regulation of T cell apoptotic process (GO:0070233) | 4.09955283 |
| 15 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.02633017 |
| 16 | negative regulation of interleukin-12 production (GO:0032695) | 3.98592119 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.91420187 |
| 18 | T cell migration (GO:0072678) | 3.90183463 |
| 19 | response to hydroperoxide (GO:0033194) | 3.88086771 |
| 20 | cellular extravasation (GO:0045123) | 3.85706958 |
| 21 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.83691300 |
| 22 | response to peptidoglycan (GO:0032494) | 3.83243149 |
| 23 | B cell proliferation (GO:0042100) | 3.80892057 |
| 24 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.75028072 |
| 25 | positive regulation of B cell differentiation (GO:0045579) | 3.73802281 |
| 26 | B cell receptor signaling pathway (GO:0050853) | 3.66442539 |
| 27 | detection of other organism (GO:0098543) | 3.62346102 |
| 28 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.61269941 |
| 29 | B cell mediated immunity (GO:0019724) | 3.57892692 |
| 30 | type I interferon signaling pathway (GO:0060337) | 3.53023902 |
| 31 | cellular response to type I interferon (GO:0071357) | 3.53023902 |
| 32 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.52239123 |
| 33 | detection of bacterium (GO:0016045) | 3.49680848 |
| 34 | response to type I interferon (GO:0034340) | 3.48680824 |
| 35 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.48562638 |
| 36 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.48562638 |
| 37 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.48548364 |
| 38 | T cell homeostasis (GO:0043029) | 3.44666181 |
| 39 | macrophage activation involved in immune response (GO:0002281) | 3.44657533 |
| 40 | myeloid cell activation involved in immune response (GO:0002275) | 3.44402075 |
| 41 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.42286372 |
| 42 | germinal center formation (GO:0002467) | 3.40955349 |
| 43 | positive regulation by symbiont of host defense response (GO:0052509) | 3.40429326 |
| 44 | modulation by symbiont of host defense response (GO:0052031) | 3.40429326 |
| 45 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.40429326 |
| 46 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.40429326 |
| 47 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.40429326 |
| 48 | modulation by symbiont of host immune response (GO:0052553) | 3.40429326 |
| 49 | neutrophil activation (GO:0042119) | 3.35159890 |
| 50 | granulocyte activation (GO:0036230) | 3.35032124 |
| 51 | regulation of gamma-delta T cell activation (GO:0046643) | 3.34806799 |
| 52 | positive regulation of type 2 immune response (GO:0002830) | 3.30317239 |
| 53 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.24258949 |
| 54 | leukocyte aggregation (GO:0070486) | 3.16409722 |
| 55 | positive regulation of T-helper cell differentiation (GO:0045624) | 3.16122016 |
| 56 | regulation of antigen processing and presentation (GO:0002577) | 3.14106904 |
| 57 | leukocyte degranulation (GO:0043299) | 3.13099471 |
| 58 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.10417098 |
| 59 | positive thymic T cell selection (GO:0045059) | 3.09875792 |
| 60 | regulation of B cell differentiation (GO:0045577) | 3.09236918 |
| 61 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.06376211 |
| 62 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.06265890 |
| 63 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.06251698 |
| 64 | regulation of type 2 immune response (GO:0002828) | 3.05539764 |
| 65 | regulation of regulatory T cell differentiation (GO:0045589) | 3.04394655 |
| 66 | regulation of T cell apoptotic process (GO:0070232) | 3.01754517 |
| 67 | negative thymic T cell selection (GO:0045060) | 3.01382245 |
| 68 | mast cell activation (GO:0045576) | 3.00957624 |
| 69 | negative regulation of T cell mediated immunity (GO:0002710) | 3.00886579 |
| 70 | regulation of T-helper cell differentiation (GO:0045622) | 2.97644688 |
| 71 | T cell differentiation in thymus (GO:0033077) | 2.96950366 |
| 72 | lymphocyte homeostasis (GO:0002260) | 2.96566703 |
| 73 | negative regulation of type 2 immune response (GO:0002829) | 2.96466528 |
| 74 | positive regulation of antigen processing and presentation (GO:0002579) | 2.95444249 |
| 75 | negative T cell selection (GO:0043383) | 2.95222435 |
| 76 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.93604195 |
| 77 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.91866679 |
| 78 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.88478007 |
| 79 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.88350212 |
| 80 | regulation of interferon-alpha production (GO:0032647) | 2.84434912 |
| 81 | lymphocyte proliferation (GO:0046651) | 2.83874419 |
| 82 | detection of external biotic stimulus (GO:0098581) | 2.83708282 |
| 83 | mononuclear cell proliferation (GO:0032943) | 2.83141725 |
| 84 | regulation of mast cell activation (GO:0033003) | 2.82812928 |
| 85 | positive regulation of isotype switching (GO:0045830) | 2.82589989 |
| 86 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.82588738 |
| 87 | regulation of T cell tolerance induction (GO:0002664) | 2.82162090 |
| 88 | negative regulation of leukocyte apoptotic process (GO:2000107) | 2.80695532 |
| 89 | positive regulation of mast cell activation (GO:0033005) | 2.80512871 |
| 90 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.80465220 |
| 91 | defense response to protozoan (GO:0042832) | 2.79811824 |
| 92 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.79496910 |
| 93 | regulation of mast cell degranulation (GO:0043304) | 2.77878788 |
| 94 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.77666598 |
| 95 | adaptive immune response (GO:0002250) | 2.75901413 |
| 96 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.75886159 |
| 97 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.74857091 |
| 98 | dendritic cell chemotaxis (GO:0002407) | 2.73836943 |
| 99 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.73169647 |
| 100 | activated T cell proliferation (GO:0050798) | 2.73119089 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.43066128 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.63779925 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.63551520 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.55308800 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.15268622 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.56706311 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.44136678 |
| 8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.37571669 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.36295512 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.32675017 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.03633181 |
| 12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.88045479 |
| 13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.82510943 |
| 14 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.81715663 |
| 15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.78699027 |
| 16 | MYB_26560356_Chip-Seq_TH2_Human | 2.66108859 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.62783527 |
| 18 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.61086755 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.60194790 |
| 20 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.48570415 |
| 21 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.46727243 |
| 22 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.46607302 |
| 23 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.46491695 |
| 24 | SPI1_23127762_ChIP-Seq_K562_Human | 2.44699347 |
| 25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.37439705 |
| 26 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.35793558 |
| 27 | MYC_22102868_ChIP-Seq_BL_Human | 2.33659543 |
| 28 | GATA1_22025678_ChIP-Seq_K562_Human | 2.27726526 |
| 29 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.21200470 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.18671907 |
| 31 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 2.16226369 |
| 32 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.15993691 |
| 33 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.15540907 |
| 34 | MYB_26560356_Chip-Seq_TH1_Human | 2.14604565 |
| 35 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.09821899 |
| 36 | MAF_26560356_Chip-Seq_TH1_Human | 2.08895307 |
| 37 | UTX_26944678_Chip-Seq_JUKART_Human | 2.03788468 |
| 38 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.93257270 |
| 39 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.90194310 |
| 40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.87841541 |
| 41 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.87364870 |
| 42 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.85133614 |
| 43 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.72885186 |
| 44 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.68981186 |
| 45 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.59453429 |
| 46 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57327389 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55959338 |
| 48 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.53835535 |
| 49 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.53217444 |
| 50 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.50040224 |
| 51 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.48361222 |
| 52 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.48318801 |
| 53 | MAF_26560356_Chip-Seq_TH2_Human | 1.45685680 |
| 54 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.45601999 |
| 55 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.41819569 |
| 56 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.41097106 |
| 57 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.39653643 |
| 58 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.38338101 |
| 59 | GATA1_19941826_ChIP-Seq_K562_Human | 1.35849291 |
| 60 | GATA3_26560356_Chip-Seq_TH2_Human | 1.34050525 |
| 61 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.33158439 |
| 62 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.33140671 |
| 63 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.31682720 |
| 64 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.25534460 |
| 65 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21213570 |
| 66 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.21035680 |
| 67 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.16279294 |
| 68 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14051151 |
| 69 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12980878 |
| 70 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.12537523 |
| 71 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.11253749 |
| 72 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.10370920 |
| 73 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06522398 |
| 74 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04240712 |
| 75 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.03804511 |
| 76 | GATA2_19941826_ChIP-Seq_K562_Human | 1.01825723 |
| 77 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.01156366 |
| 78 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.00534557 |
| 79 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.99409670 |
| 80 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98682717 |
| 81 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.98189799 |
| 82 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.95976884 |
| 83 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95972304 |
| 84 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.94941481 |
| 85 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.92641064 |
| 86 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.91781393 |
| 87 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.89378970 |
| 88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88276346 |
| 89 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.84627764 |
| 90 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.82378895 |
| 91 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.81087072 |
| 92 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.80953915 |
| 93 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.79770863 |
| 94 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.78823032 |
| 95 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.76797485 |
| 96 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.75577588 |
| 97 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.74654757 |
| 98 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.74474940 |
| 99 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.71752423 |
| 100 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.69453625 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.25432232 |
| 2 | MP0003303_peritoneal_inflammation | 3.94222714 |
| 3 | MP0009278_abnormal_bone_marrow | 3.92569991 |
| 4 | MP0005451_abnormal_body_composition | 3.92171453 |
| 5 | MP0005671_abnormal_response_to | 3.66597446 |
| 6 | MP0009785_altered_susceptibility_to | 3.46898458 |
| 7 | MP0002132_abnormal_respiratory_system | 3.42366600 |
| 8 | MP0003436_decreased_susceptibility_to | 3.25542665 |
| 9 | MP0003724_increased_susceptibility_to | 3.23383232 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 3.11618593 |
| 11 | MP0000685_abnormal_immune_system | 2.99820768 |
| 12 | MP0005387_immune_system_phenotype | 2.97684679 |
| 13 | MP0001790_abnormal_immune_system | 2.97684679 |
| 14 | MP0005000_abnormal_immune_tolerance | 2.90803622 |
| 15 | MP0001800_abnormal_humoral_immune | 2.90197613 |
| 16 | MP0004947_skin_inflammation | 2.83467046 |
| 17 | MP0005464_abnormal_platelet_physiology | 2.82308834 |
| 18 | MP0002419_abnormal_innate_immunity | 2.44794445 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.43170417 |
| 20 | MP0002723_abnormal_immune_serum | 2.39541674 |
| 21 | MP0002166_altered_tumor_susceptibility | 2.38826130 |
| 22 | MP0005025_abnormal_response_to | 2.37973367 |
| 23 | MP0001545_abnormal_hematopoietic_system | 2.34171200 |
| 24 | MP0005397_hematopoietic_system_phenotyp | 2.34171200 |
| 25 | MP0010155_abnormal_intestine_physiology | 2.23555416 |
| 26 | MP0002420_abnormal_adaptive_immunity | 2.16459734 |
| 27 | MP0001819_abnormal_immune_cell | 2.14362978 |
| 28 | MP0006082_CNS_inflammation | 2.13983000 |
| 29 | MP0002398_abnormal_bone_marrow | 1.94760864 |
| 30 | MP0003763_abnormal_thymus_physiology | 1.93684155 |
| 31 | MP0002006_tumorigenesis | 1.89850717 |
| 32 | MP0005058_abnormal_lysosome_morphology | 1.87597497 |
| 33 | MP0003300_gastrointestinal_ulcer | 1.82136546 |
| 34 | MP0002876_abnormal_thyroid_physiology | 1.80899591 |
| 35 | MP0002405_respiratory_system_inflammati | 1.78015330 |
| 36 | MP0000716_abnormal_immune_system | 1.77378725 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.63034027 |
| 38 | MP0001533_abnormal_skeleton_physiology | 1.60855624 |
| 39 | MP0001849_ear_inflammation | 1.56932299 |
| 40 | MP0000689_abnormal_spleen_morphology | 1.55347448 |
| 41 | MP0002722_abnormal_immune_system | 1.53134161 |
| 42 | MP0003172_abnormal_lysosome_physiology | 1.48225690 |
| 43 | MP0002429_abnormal_blood_cell | 1.44762390 |
| 44 | MP0009764_decreased_sensitivity_to | 1.43688944 |
| 45 | MP0002998_abnormal_bone_remodeling | 1.39574336 |
| 46 | MP0008004_abnormal_stomach_pH | 1.38444304 |
| 47 | MP0000703_abnormal_thymus_morphology | 1.35741558 |
| 48 | MP0002933_joint_inflammation | 1.32855476 |
| 49 | MP0004510_myositis | 1.32085851 |
| 50 | MP0009333_abnormal_splenocyte_physiolog | 1.31575641 |
| 51 | MP0008469_abnormal_protein_level | 1.25176475 |
| 52 | MP0000343_altered_response_to | 1.14738815 |
| 53 | MP0001853_heart_inflammation | 1.11847669 |
| 54 | MP0003828_pulmonary_edema | 1.11431347 |
| 55 | MP0002396_abnormal_hematopoietic_system | 1.10106397 |
| 56 | MP0004808_abnormal_hematopoietic_stem | 1.05713330 |
| 57 | MP0000490_abnormal_crypts_of | 1.03695810 |
| 58 | MP0001663_abnormal_digestive_system | 1.03551772 |
| 59 | MP0003075_altered_response_to | 1.01525681 |
| 60 | MP0000465_gastrointestinal_hemorrhage | 0.97972056 |
| 61 | MP0000604_amyloidosis | 0.93123674 |
| 62 | MP0010094_abnormal_chromosome_stability | 0.92817227 |
| 63 | MP0000858_altered_metastatic_potential | 0.91080607 |
| 64 | MP0005310_abnormal_salivary_gland | 0.89197991 |
| 65 | MP0009840_abnormal_foam_cell | 0.89031347 |
| 66 | MP0003448_altered_tumor_morphology | 0.88288448 |
| 67 | MP0001879_abnormal_lymphatic_vessel | 0.84992550 |
| 68 | MP0003656_abnormal_erythrocyte_physiolo | 0.83769512 |
| 69 | MP0000249_abnormal_blood_vessel | 0.78087740 |
| 70 | MP0002009_preneoplasia | 0.77513193 |
| 71 | MP0003191_abnormal_cellular_cholesterol | 0.77359889 |
| 72 | MP0009763_increased_sensitivity_to | 0.76973054 |
| 73 | MP0002332_abnormal_exercise_endurance | 0.75836091 |
| 74 | MP0005167_abnormal_blood-brain_barrier | 0.74021800 |
| 75 | MP0008260_abnormal_autophagy | 0.72345259 |
| 76 | MP0005166_decreased_susceptibility_to | 0.72080623 |
| 77 | MP0001851_eye_inflammation | 0.72054087 |
| 78 | MP0003183_abnormal_peptide_metabolism | 0.69812206 |
| 79 | MP0002095_abnormal_skin_pigmentation | 0.68620306 |
| 80 | MP0003866_abnormal_defecation | 0.66491025 |
| 81 | MP0009765_abnormal_xenobiotic_induced | 0.65527924 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.63231765 |
| 83 | MP0003795_abnormal_bone_structure | 0.62667930 |
| 84 | MP0003690_abnormal_glial_cell | 0.62501088 |
| 85 | MP0005381_digestive/alimentary_phenotyp | 0.60170128 |
| 86 | MP0005164_abnormal_response_to | 0.59957097 |
| 87 | MP0003091_abnormal_cell_migration | 0.59859929 |
| 88 | MP0005390_skeleton_phenotype | 0.57042279 |
| 89 | MP0003453_abnormal_keratinocyte_physiol | 0.56702582 |
| 90 | MP0004883_abnormal_blood_vessel | 0.56396723 |
| 91 | MP0004084_abnormal_cardiac_muscle | 0.53043347 |
| 92 | MP0008057_abnormal_DNA_replication | 0.52548032 |
| 93 | MP0003806_abnormal_nucleotide_metabolis | 0.49751617 |
| 94 | MP0002138_abnormal_hepatobiliary_system | 0.49412015 |
| 95 | MP0003045_fibrosis | 0.47130371 |
| 96 | MP0001191_abnormal_skin_condition | 0.45493789 |
| 97 | MP0001873_stomach_inflammation | 0.44142386 |
| 98 | MP0000920_abnormal_myelination | 0.44030500 |
| 99 | MP0001243_abnormal_dermal_layer | 0.41421663 |
| 100 | MP0000015_abnormal_ear_pigmentation | 0.40455873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of B cell number (HP:0010975) | 9.13046018 |
| 2 | Panhypogammaglobulinemia (HP:0003139) | 8.47137740 |
| 3 | Hypoplasia of the thymus (HP:0000778) | 8.25637570 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 8.04227448 |
| 5 | T lymphocytopenia (HP:0005403) | 7.02706807 |
| 6 | Combined immunodeficiency (HP:0005387) | 6.99806475 |
| 7 | Thyroiditis (HP:0100646) | 6.88353415 |
| 8 | Hypoproteinemia (HP:0003075) | 6.35030603 |
| 9 | Abnormality of T cell number (HP:0011839) | 6.08725240 |
| 10 | Eosinophilia (HP:0001880) | 5.77912049 |
| 11 | Granulocytopenia (HP:0001913) | 5.21586374 |
| 12 | Recurrent viral infections (HP:0004429) | 5.07561953 |
| 13 | Recurrent fungal infections (HP:0002841) | 4.58138301 |
| 14 | Abnormality of eosinophils (HP:0001879) | 4.36191378 |
| 15 | Meningitis (HP:0001287) | 4.30460023 |
| 16 | Erythroderma (HP:0001019) | 3.95505653 |
| 17 | Agammaglobulinemia (HP:0004432) | 3.94624389 |
| 18 | IgG deficiency (HP:0004315) | 3.94034405 |
| 19 | Leukocytosis (HP:0001974) | 3.92118835 |
| 20 | Abnormality of T cells (HP:0002843) | 3.65849835 |
| 21 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 3.52487405 |
| 22 | Stomatitis (HP:0010280) | 3.36460827 |
| 23 | Recurrent bacterial skin infections (HP:0005406) | 3.31361206 |
| 24 | Recurrent abscess formation (HP:0002722) | 3.28905815 |
| 25 | Sepsis (HP:0100806) | 3.20597110 |
| 26 | Abnormality of macrophages (HP:0004311) | 3.18572510 |
| 27 | Myositis (HP:0100614) | 3.12698514 |
| 28 | Retrobulbar optic neuritis (HP:0100654) | 3.12330792 |
| 29 | Optic neuritis (HP:0100653) | 3.12330792 |
| 30 | Eczematoid dermatitis (HP:0000976) | 3.09109024 |
| 31 | Abnormality of glycolipid metabolism (HP:0010969) | 3.08431407 |
| 32 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.08431407 |
| 33 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.08431407 |
| 34 | Orchitis (HP:0100796) | 3.05461417 |
| 35 | Prolonged bleeding time (HP:0003010) | 2.94699501 |
| 36 | Cellulitis (HP:0100658) | 2.91300928 |
| 37 | Purpura (HP:0000979) | 2.78624526 |
| 38 | Spontaneous hematomas (HP:0007420) | 2.78040475 |
| 39 | Petechiae (HP:0000967) | 2.75203982 |
| 40 | Abnormality of the thymus (HP:0000777) | 2.73178533 |
| 41 | Encephalitis (HP:0002383) | 2.59232968 |
| 42 | Keratoconjunctivitis sicca (HP:0001097) | 2.58437328 |
| 43 | Recurrent bronchitis (HP:0002837) | 2.55959087 |
| 44 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.52414244 |
| 45 | Autoimmune hemolytic anemia (HP:0001890) | 2.48011212 |
| 46 | Epistaxis (HP:0000421) | 2.45556732 |
| 47 | Chronic sinusitis (HP:0011109) | 2.40641560 |
| 48 | Mediastinal lymphadenopathy (HP:0100721) | 2.35354214 |
| 49 | Keratoconjunctivitis (HP:0001096) | 2.35175081 |
| 50 | Chronic obstructive pulmonary disease (HP:0006510) | 2.31874921 |
| 51 | Obstructive lung disease (HP:0006536) | 2.31874921 |
| 52 | Vasculitis (HP:0002633) | 2.25339748 |
| 53 | Increased cerebral lipofuscin (HP:0011813) | 2.24352044 |
| 54 | Abnormal platelet volume (HP:0011876) | 2.22718853 |
| 55 | Dysostosis multiplex (HP:0000943) | 2.21216596 |
| 56 | Vacuolated lymphocytes (HP:0001922) | 2.21105861 |
| 57 | Lymphoma (HP:0002665) | 2.19801771 |
| 58 | Increased IgM level (HP:0003496) | 2.18439641 |
| 59 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.15238556 |
| 60 | Gingival bleeding (HP:0000225) | 2.10462950 |
| 61 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.08570764 |
| 62 | Recurrent skin infections (HP:0001581) | 2.08163071 |
| 63 | Osteomyelitis (HP:0002754) | 2.05896363 |
| 64 | Verrucae (HP:0200043) | 2.05005326 |
| 65 | Papilloma (HP:0012740) | 2.05005326 |
| 66 | Recurrent pneumonia (HP:0006532) | 2.03480465 |
| 67 | Autoimmune thrombocytopenia (HP:0001973) | 2.03073523 |
| 68 | B lymphocytopenia (HP:0010976) | 10.0047425 |
| 69 | Hematochezia (HP:0002573) | 1.99560516 |
| 70 | Increased mean platelet volume (HP:0011877) | 1.98898292 |
| 71 | Gastrointestinal infarctions (HP:0005244) | 1.95575563 |
| 72 | Pulmonary infiltrates (HP:0002113) | 1.91977996 |
| 73 | Increased IgE level (HP:0003212) | 1.91667896 |
| 74 | Conjunctival telangiectasia (HP:0000524) | 1.91353857 |
| 75 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.88951741 |
| 76 | Abnormality of the prostate (HP:0008775) | 1.85960356 |
| 77 | Arterial thrombosis (HP:0004420) | 1.85706998 |
| 78 | Loss of speech (HP:0002371) | 1.85698418 |
| 79 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.81800589 |
| 80 | Hemoptysis (HP:0002105) | 1.79885925 |
| 81 | Hepatosplenomegaly (HP:0001433) | 1.76101534 |
| 82 | Pulmonary embolism (HP:0002204) | 1.72211947 |
| 83 | Menorrhagia (HP:0000132) | 1.68000394 |
| 84 | Recurrent cutaneous fungal infections (HP:0011370) | 1.67725614 |
| 85 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.67725614 |
| 86 | Hypergammaglobulinemia (HP:0010702) | 1.66410798 |
| 87 | Inflammation of the large intestine (HP:0002037) | 1.64197830 |
| 88 | Chronic diarrhea (HP:0002028) | 1.62759561 |
| 89 | Gangrene (HP:0100758) | 1.62707043 |
| 90 | Acute lymphatic leukemia (HP:0006721) | 1.60916308 |
| 91 | Urticaria (HP:0001025) | 1.57645319 |
| 92 | Gastrointestinal inflammation (HP:0004386) | 1.54655732 |
| 93 | Chest pain (HP:0100749) | 1.54148461 |
| 94 | Acute hepatic failure (HP:0006554) | 1.53985578 |
| 95 | Chronic otitis media (HP:0000389) | 1.53829047 |
| 96 | Colitis (HP:0002583) | 1.53707198 |
| 97 | Recurrent lower respiratory tract infections (HP:0002783) | 1.52206861 |
| 98 | Amaurosis fugax (HP:0100576) | 1.52181222 |
| 99 | Lymphopenia (HP:0001888) | 1.51251587 |
| 100 | Pruritus (HP:0000989) | 1.50942433 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.26198143 |
| 2 | MAP4K1 | 3.31564419 |
| 3 | MAP3K14 | 3.19561760 |
| 4 | MAP3K13 | 3.06466149 |
| 5 | TAOK3 | 2.63026613 |
| 6 | BLK | 2.47917747 |
| 7 | TXK | 2.38918274 |
| 8 | TYK2 | 2.31822921 |
| 9 | IRAK4 | 2.23123143 |
| 10 | ERN1 | 2.20886476 |
| 11 | FES | 2.18260815 |
| 12 | BTK | 2.16567197 |
| 13 | PIK3CG | 2.12776820 |
| 14 | SYK | 2.05925504 |
| 15 | MAP2K3 | 2.04533157 |
| 16 | CSF1R | 1.90993088 |
| 17 | PRPF4B | 1.89842085 |
| 18 | CSK | 1.84613377 |
| 19 | ZAP70 | 1.83105713 |
| 20 | IRAK3 | 1.79671091 |
| 21 | SIK3 | 1.72409662 |
| 22 | TBK1 | 1.71779030 |
| 23 | IKBKB | 1.69319901 |
| 24 | GRK7 | 1.68190416 |
| 25 | KIT | 1.66680423 |
| 26 | TAOK2 | 1.66174331 |
| 27 | LYN | 1.62364533 |
| 28 | IKBKE | 1.62067924 |
| 29 | TEC | 1.59030140 |
| 30 | EIF2AK3 | 1.54309407 |
| 31 | MARK3 | 1.52153731 |
| 32 | TAOK1 | 1.51992538 |
| 33 | MAP3K3 | 1.51611098 |
| 34 | MATK | 1.47450975 |
| 35 | HCK | 1.47335339 |
| 36 | JAK3 | 1.46365876 |
| 37 | BMPR2 | 1.42975436 |
| 38 | FGR | 1.38583895 |
| 39 | JAK1 | 1.34404931 |
| 40 | LCK | 1.25025507 |
| 41 | NLK | 1.24541198 |
| 42 | GRK6 | 1.24339357 |
| 43 | TGFBR2 | 1.20848479 |
| 44 | ITK | 1.20747801 |
| 45 | MAP3K11 | 1.19891884 |
| 46 | TNK2 | 1.15375014 |
| 47 | MAP3K10 | 1.15338109 |
| 48 | STK10 | 1.10982903 |
| 49 | JAK2 | 1.09938593 |
| 50 | PIM2 | 1.07100834 |
| 51 | CLK1 | 0.99746875 |
| 52 | PIM1 | 0.98274143 |
| 53 | TYRO3 | 0.91756296 |
| 54 | FLT3 | 0.87746898 |
| 55 | MAP3K5 | 0.82907276 |
| 56 | MAP3K1 | 0.80440138 |
| 57 | MAPKAPK3 | 0.80004193 |
| 58 | IRAK1 | 0.77238526 |
| 59 | PDK1 | 0.76320719 |
| 60 | FGFR3 | 0.70501904 |
| 61 | CHUK | 0.68607495 |
| 62 | TESK2 | 0.68445939 |
| 63 | ADRBK2 | 0.67560445 |
| 64 | MAPK12 | 0.65114633 |
| 65 | MET | 0.64810095 |
| 66 | MARK2 | 0.64769203 |
| 67 | SCYL2 | 0.64756013 |
| 68 | MOS | 0.58924284 |
| 69 | MAPK4 | 0.56462492 |
| 70 | BMPR1B | 0.56304361 |
| 71 | CDC42BPA | 0.56039665 |
| 72 | RPS6KL1 | 0.55525153 |
| 73 | RPS6KC1 | 0.55525153 |
| 74 | TGFBR1 | 0.54779655 |
| 75 | IRAK2 | 0.54538711 |
| 76 | PRKCQ | 0.54205799 |
| 77 | HIPK2 | 0.52542742 |
| 78 | CAMKK2 | 0.51752737 |
| 79 | CDK6 | 0.50932959 |
| 80 | MAPK7 | 0.50744562 |
| 81 | YES1 | 0.50727169 |
| 82 | CDK4 | 0.50598090 |
| 83 | BMX | 0.49701597 |
| 84 | MAP3K7 | 0.48323261 |
| 85 | FYN | 0.45861720 |
| 86 | RPS6KB1 | 0.45312175 |
| 87 | SIK2 | 0.44609826 |
| 88 | RPS6KA6 | 0.44587150 |
| 89 | CDK12 | 0.44407173 |
| 90 | MAPK11 | 0.41900710 |
| 91 | MELK | 0.39215630 |
| 92 | PDPK1 | 0.39023810 |
| 93 | RET | 0.35434655 |
| 94 | STK11 | 0.33492265 |
| 95 | MAP3K8 | 0.32915673 |
| 96 | ABL1 | 0.32381462 |
| 97 | DYRK1B | 0.32278353 |
| 98 | CDK9 | 0.29329124 |
| 99 | PRKD2 | 0.29141941 |
| 100 | ARAF | 0.28458542 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.68949348 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 2.87920297 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.78131242 |
| 4 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.59234404 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.53291447 |
| 6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.45569561 |
| 7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.44531417 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.37580901 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.31969056 |
| 10 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.24484829 |
| 11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.19018930 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.16775643 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.07868710 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.05895989 |
| 15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.02183902 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.02135228 |
| 17 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.84733540 |
| 18 | Other glycan degradation_Homo sapiens_hsa00511 | 1.83691567 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.82323674 |
| 20 | Malaria_Homo sapiens_hsa05144 | 1.78698524 |
| 21 | Tuberculosis_Homo sapiens_hsa05152 | 1.75999892 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.73749885 |
| 23 | Measles_Homo sapiens_hsa05162 | 1.73359657 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.66537150 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.62423994 |
| 26 | Viral myocarditis_Homo sapiens_hsa05416 | 1.60574970 |
| 27 | Influenza A_Homo sapiens_hsa05164 | 1.59182802 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.51864387 |
| 29 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.51192668 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.50091975 |
| 31 | Legionellosis_Homo sapiens_hsa05134 | 1.48489081 |
| 32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.47413228 |
| 33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.46874267 |
| 34 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.38234800 |
| 35 | Lysosome_Homo sapiens_hsa04142 | 1.35101343 |
| 36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.34469939 |
| 37 | Platelet activation_Homo sapiens_hsa04611 | 1.28908690 |
| 38 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.25901049 |
| 39 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.25092497 |
| 40 | Pertussis_Homo sapiens_hsa05133 | 1.19794367 |
| 41 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.19419686 |
| 42 | Hepatitis B_Homo sapiens_hsa05161 | 1.17283202 |
| 43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.16329238 |
| 44 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.13333551 |
| 45 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.11889262 |
| 46 | Hepatitis C_Homo sapiens_hsa05160 | 1.06677394 |
| 47 | Phagosome_Homo sapiens_hsa04145 | 1.06531800 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.03109171 |
| 49 | Shigellosis_Homo sapiens_hsa05131 | 1.02237714 |
| 50 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.98685219 |
| 51 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.97952339 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.90572184 |
| 53 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.87261445 |
| 54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.86870390 |
| 55 | Salmonella infection_Homo sapiens_hsa05132 | 0.85966862 |
| 56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.84636099 |
| 57 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.84092245 |
| 58 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.82488780 |
| 59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.77929474 |
| 60 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.74930912 |
| 61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.72357759 |
| 62 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.71319852 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.66823902 |
| 64 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.65216603 |
| 65 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.65126144 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62760556 |
| 67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.61719800 |
| 68 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.61071377 |
| 69 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59474290 |
| 70 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.57364740 |
| 71 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.56800688 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.52116126 |
| 73 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.48417644 |
| 74 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48008453 |
| 75 | Endocytosis_Homo sapiens_hsa04144 | 0.47505213 |
| 76 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.46077955 |
| 77 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.45741071 |
| 78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.45467499 |
| 79 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.43914388 |
| 80 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.43580524 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.42256555 |
| 82 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.41747350 |
| 83 | Amoebiasis_Homo sapiens_hsa05146 | 0.39788353 |
| 84 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.38969205 |
| 85 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.37978003 |
| 86 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.34869037 |
| 87 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.31164092 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29581662 |
| 89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28949792 |
| 90 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.27733618 |
| 91 | Insulin resistance_Homo sapiens_hsa04931 | 0.27680163 |
| 92 | Prostate cancer_Homo sapiens_hsa05215 | 0.26647678 |
| 93 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.26603479 |
| 94 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.25903185 |
| 95 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.24446610 |
| 96 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.23822974 |
| 97 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.21966453 |
| 98 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.20777831 |
| 99 | Bladder cancer_Homo sapiens_hsa05219 | 0.20170030 |
| 100 | Colorectal cancer_Homo sapiens_hsa05210 | 0.19449787 |

