

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | branching involved in prostate gland morphogenesis (GO:0060442) | 8.00010912 |
| 2 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 7.42872734 |
| 3 | piRNA metabolic process (GO:0034587) | 6.82341395 |
| 4 | negative regulation of cell killing (GO:0031342) | 5.86875713 |
| 5 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.86875713 |
| 6 | cellular response to interleukin-15 (GO:0071350) | 5.42307793 |
| 7 | negative T cell selection (GO:0043383) | 5.30310733 |
| 8 | negative regulation of stress fiber assembly (GO:0051497) | 5.15470185 |
| 9 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 5.11536730 |
| 10 | negative thymic T cell selection (GO:0045060) | 5.08974610 |
| 11 | positive regulation of macrophage cytokine production (GO:0060907) | 5.02139206 |
| 12 | prostate gland epithelium morphogenesis (GO:0060740) | 5.00189197 |
| 13 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 4.89117053 |
| 14 | DNA methylation involved in gamete generation (GO:0043046) | 4.84921175 |
| 15 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.84525009 |
| 16 | positive thymic T cell selection (GO:0045059) | 4.77492962 |
| 17 | opsonization (GO:0008228) | 4.72840923 |
| 18 | artery development (GO:0060840) | 4.72120482 |
| 19 | positive T cell selection (GO:0043368) | 4.65924029 |
| 20 | biotin metabolic process (GO:0006768) | 4.54910849 |
| 21 | regulation of receptor binding (GO:1900120) | 4.54469207 |
| 22 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 4.47180350 |
| 23 | response to testosterone (GO:0033574) | 4.45323322 |
| 24 | response to interleukin-15 (GO:0070672) | 4.42807983 |
| 25 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 4.39614776 |
| 26 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.36216953 |
| 27 | positive regulation of steroid hormone secretion (GO:2000833) | 4.29377933 |
| 28 | positive regulation of granulocyte differentiation (GO:0030854) | 4.28640228 |
| 29 | thymic T cell selection (GO:0045061) | 4.27214058 |
| 30 | mitotic cell cycle arrest (GO:0071850) | 4.04740063 |
| 31 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.97944362 |
| 32 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.93519169 |
| 33 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.90299880 |
| 34 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.90299880 |
| 35 | regulation of protein polyubiquitination (GO:1902914) | 3.89098969 |
| 36 | myeloid leukocyte mediated immunity (GO:0002444) | 3.88404468 |
| 37 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.88241714 |
| 38 | sex differentiation (GO:0007548) | 3.79308141 |
| 39 | Golgi to endosome transport (GO:0006895) | 3.78135258 |
| 40 | regulation of transcription from RNA polymerase III promoter (GO:0006359) | 3.76198077 |
| 41 | epithelial cell maturation (GO:0002070) | 3.75085263 |
| 42 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.74295981 |
| 43 | cytidine metabolic process (GO:0046087) | 3.72746410 |
| 44 | cytidine catabolic process (GO:0006216) | 3.72746410 |
| 45 | cytidine deamination (GO:0009972) | 3.72746410 |
| 46 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.72394669 |
| 47 | T cell selection (GO:0045058) | 3.72205360 |
| 48 | mitochondrion degradation (GO:0000422) | 3.71069342 |
| 49 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.67139676 |
| 50 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.65832901 |
| 51 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.65269812 |
| 52 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.61132624 |
| 53 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.57927531 |
| 54 | DNA deamination (GO:0045006) | 3.54576121 |
| 55 | positive regulation of cell killing (GO:0031343) | 3.53453059 |
| 56 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.50644045 |
| 57 | negative regulation of DNA repair (GO:0045738) | 3.46718225 |
| 58 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.41451606 |
| 59 | histone H3-K4 trimethylation (GO:0080182) | 3.41048645 |
| 60 | regulation of cell killing (GO:0031341) | 3.39941193 |
| 61 | androgen receptor signaling pathway (GO:0030521) | 3.39700897 |
| 62 | activated T cell proliferation (GO:0050798) | 3.33313419 |
| 63 | regulation of ARF protein signal transduction (GO:0032012) | 3.26932685 |
| 64 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.22865689 |
| 65 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.21485160 |
| 66 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.19834489 |
| 67 | positive regulation of defense response to virus by host (GO:0002230) | 3.17735992 |
| 68 | adenosine metabolic process (GO:0046085) | 3.17118117 |
| 69 | regulation of gamma-delta T cell activation (GO:0046643) | 3.17056938 |
| 70 | negative regulation of T cell mediated immunity (GO:0002710) | 3.15470175 |
| 71 | regulation of regulatory T cell differentiation (GO:0045589) | 3.15301848 |
| 72 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.14537992 |
| 73 | adaptation of signaling pathway (GO:0023058) | 3.14451898 |
| 74 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.14095182 |
| 75 | alpha-beta T cell differentiation (GO:0046632) | 3.06305839 |
| 76 | positive regulation of fibroblast migration (GO:0010763) | 3.06256734 |
| 77 | T-helper cell differentiation (GO:0042093) | 3.06222908 |
| 78 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.06222908 |
| 79 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.03003345 |
| 80 | mast cell activation (GO:0045576) | 3.02035150 |
| 81 | regulation of RIG-I signaling pathway (GO:0039535) | 3.01935710 |
| 82 | regulation of macrophage cytokine production (GO:0010935) | 3.00904855 |
| 83 | positive regulation by host of viral transcription (GO:0043923) | 2.99777376 |
| 84 | leukocyte aggregation (GO:0070486) | 2.96886477 |
| 85 | positive regulation of T cell chemotaxis (GO:0010820) | 2.91961090 |
| 86 | regulation of T cell chemotaxis (GO:0010819) | 2.91961090 |
| 87 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.91651774 |
| 88 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.90511426 |
| 89 | cellular response to interleukin-4 (GO:0071353) | 2.90288723 |
| 90 | cellular response to nicotine (GO:0071316) | 2.87737328 |
| 91 | pharyngeal system development (GO:0060037) | 2.81062522 |
| 92 | gene silencing by RNA (GO:0031047) | 2.78101292 |
| 93 | positive regulation of cytokine production involved in immune response (GO:0002720) | 2.76858919 |
| 94 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.76693028 |
| 95 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.76693028 |
| 96 | T cell differentiation involved in immune response (GO:0002292) | 2.76693028 |
| 97 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.76625480 |
| 98 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 2.73839818 |
| 99 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.70329441 |
| 100 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.69905929 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.25124902 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.49136243 |
| 3 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 4.21790236 |
| 4 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 3.09744993 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.06771273 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.05282573 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.99004158 |
| 8 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.92989786 |
| 9 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 2.84285680 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.77261912 |
| 11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.55657195 |
| 12 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.54117430 |
| 13 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.49894306 |
| 14 | MYC_22102868_ChIP-Seq_BL_Human | 2.47063824 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.45895575 |
| 16 | ERG_20517297_ChIP-Seq_VCAP_Human | 2.42251249 |
| 17 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.37541651 |
| 18 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.31503880 |
| 19 | UTX_26944678_Chip-Seq_JUKART_Human | 2.29001096 |
| 20 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.18606524 |
| 21 | MYB_26560356_Chip-Seq_TH1_Human | 2.17431927 |
| 22 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.09422887 |
| 23 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.08027771 |
| 24 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 2.04089598 |
| 25 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.01170289 |
| 26 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.97169176 |
| 27 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.96429310 |
| 28 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.94253599 |
| 29 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.92735232 |
| 30 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.85901662 |
| 31 | MAF_26560356_Chip-Seq_TH1_Human | 1.84555686 |
| 32 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.82028303 |
| 33 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.80798339 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.78331723 |
| 35 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.76343845 |
| 36 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.71273630 |
| 37 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70317375 |
| 38 | MAF_26560356_Chip-Seq_TH2_Human | 1.69791471 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.65748975 |
| 40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.65107904 |
| 41 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.63138049 |
| 42 | SPI1_23127762_ChIP-Seq_K562_Human | 1.62506696 |
| 43 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.61364459 |
| 44 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.60564497 |
| 45 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.59015687 |
| 46 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.54880403 |
| 47 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.54594586 |
| 48 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.54430101 |
| 49 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.54195804 |
| 50 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.53130844 |
| 51 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.51185757 |
| 52 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49085890 |
| 53 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.46718164 |
| 54 | AR_20517297_ChIP-Seq_VCAP_Human | 1.45399213 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.43169568 |
| 56 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41918392 |
| 57 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.40963887 |
| 58 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.40674039 |
| 59 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.38800393 |
| 60 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.38679429 |
| 61 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34281445 |
| 62 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.29769176 |
| 63 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.18149031 |
| 64 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.16140353 |
| 65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16057759 |
| 66 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13807348 |
| 67 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.12702367 |
| 68 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.12419920 |
| 69 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.11614913 |
| 70 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.08353864 |
| 71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06883887 |
| 72 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.02545782 |
| 73 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.00841489 |
| 74 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00411231 |
| 75 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.99230435 |
| 76 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.98743067 |
| 77 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.98207913 |
| 78 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.97608864 |
| 79 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.94205598 |
| 80 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.93921707 |
| 81 | P68_20966046_ChIP-Seq_HELA_Human | 0.93411574 |
| 82 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.93145415 |
| 83 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.92415777 |
| 84 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91931791 |
| 85 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.91236930 |
| 86 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.90094148 |
| 87 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88671208 |
| 88 | P300_27268052_Chip-Seq_Bcells_Human | 0.88590644 |
| 89 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.88375774 |
| 90 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.87750298 |
| 91 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.87577234 |
| 92 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.86783702 |
| 93 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.84785778 |
| 94 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.84113656 |
| 95 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.83276051 |
| 96 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.82848921 |
| 97 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82731146 |
| 98 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.82649575 |
| 99 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.82635267 |
| 100 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.82533172 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002009_preneoplasia | 8.24438062 |
| 2 | MP0000537_abnormal_urethra_morphology | 7.17817212 |
| 3 | MP0002166_altered_tumor_susceptibility | 5.92307227 |
| 4 | MP0003315_abnormal_perineum_morphology | 5.50363497 |
| 5 | MP0004145_abnormal_muscle_electrophysio | 4.75483178 |
| 6 | MP0002006_tumorigenesis | 4.34133399 |
| 7 | MP0005310_abnormal_salivary_gland | 3.38514399 |
| 8 | MP0002234_abnormal_pharynx_morphology | 3.10787897 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 2.66289968 |
| 10 | MP0005671_abnormal_response_to | 2.55708680 |
| 11 | MP0000516_abnormal_urinary_system | 2.49878921 |
| 12 | MP0005367_renal/urinary_system_phenotyp | 2.49878921 |
| 13 | MP0000538_abnormal_urinary_bladder | 2.23021143 |
| 14 | MP0003763_abnormal_thymus_physiology | 2.16526142 |
| 15 | MP0001873_stomach_inflammation | 2.12706232 |
| 16 | MP0001919_abnormal_reproductive_system | 2.00584517 |
| 17 | MP0005451_abnormal_body_composition | 1.84533103 |
| 18 | MP0008961_abnormal_basal_metabolism | 1.83743084 |
| 19 | MP0001835_abnormal_antigen_presentation | 1.76263983 |
| 20 | MP0003283_abnormal_digestive_organ | 1.60902724 |
| 21 | MP0004185_abnormal_adipocyte_glucose | 1.44961579 |
| 22 | MP0005647_abnormal_sex_gland | 1.38022790 |
| 23 | MP0005387_immune_system_phenotype | 1.29858182 |
| 24 | MP0001790_abnormal_immune_system | 1.29858182 |
| 25 | MP0001800_abnormal_humoral_immune | 1.29111899 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.27136108 |
| 27 | MP0005000_abnormal_immune_tolerance | 1.25800916 |
| 28 | MP0002822_catalepsy | 1.25787195 |
| 29 | MP0003724_increased_susceptibility_to | 1.23791944 |
| 30 | MP0005187_abnormal_penis_morphology | 1.18640318 |
| 31 | MP0002723_abnormal_immune_serum | 1.17910860 |
| 32 | MP0004381_abnormal_hair_follicle | 1.15457923 |
| 33 | MP0002420_abnormal_adaptive_immunity | 1.14086475 |
| 34 | MP0002398_abnormal_bone_marrow | 1.13510314 |
| 35 | MP0000703_abnormal_thymus_morphology | 1.12987477 |
| 36 | MP0001819_abnormal_immune_cell | 1.12310513 |
| 37 | MP0000685_abnormal_immune_system | 1.09151883 |
| 38 | MP0005025_abnormal_response_to | 1.09134148 |
| 39 | MP0006082_CNS_inflammation | 1.07370709 |
| 40 | MP0001348_abnormal_lacrimal_gland | 1.06999829 |
| 41 | MP0002909_abnormal_adrenal_gland | 1.03241765 |
| 42 | MP0002405_respiratory_system_inflammati | 1.02991755 |
| 43 | MP0002277_abnormal_respiratory_mucosa | 1.01382102 |
| 44 | MP0004858_abnormal_nervous_system | 1.00382223 |
| 45 | MP0004036_abnormal_muscle_relaxation | 0.99817166 |
| 46 | MP0000716_abnormal_immune_system | 0.97688890 |
| 47 | MP0002693_abnormal_pancreas_physiology | 0.96504882 |
| 48 | MP0002452_abnormal_antigen_presenting | 0.94494111 |
| 49 | MP0003866_abnormal_defecation | 0.94426375 |
| 50 | MP0006276_abnormal_autonomic_nervous | 0.92283257 |
| 51 | MP0003436_decreased_susceptibility_to | 0.91842686 |
| 52 | MP0003045_fibrosis | 0.90540634 |
| 53 | MP0002722_abnormal_immune_system | 0.87348974 |
| 54 | MP0005646_abnormal_pituitary_gland | 0.86060255 |
| 55 | MP0002876_abnormal_thyroid_physiology | 0.85958244 |
| 56 | MP0002396_abnormal_hematopoietic_system | 0.85794726 |
| 57 | MP0003787_abnormal_imprinting | 0.85234163 |
| 58 | MP0002148_abnormal_hypersensitivity_rea | 0.84954817 |
| 59 | MP0000689_abnormal_spleen_morphology | 0.84224328 |
| 60 | MP0003879_abnormal_hair_cell | 0.76855952 |
| 61 | MP0003448_altered_tumor_morphology | 0.74464879 |
| 62 | MP0009333_abnormal_splenocyte_physiolog | 0.73804734 |
| 63 | MP0004947_skin_inflammation | 0.72956615 |
| 64 | MP0002429_abnormal_blood_cell | 0.72151123 |
| 65 | MP0001853_heart_inflammation | 0.70981215 |
| 66 | MP0009785_altered_susceptibility_to | 0.69746037 |
| 67 | MP0010155_abnormal_intestine_physiology | 0.66600351 |
| 68 | MP0002638_abnormal_pupillary_reflex | 0.65546513 |
| 69 | MP0005076_abnormal_cell_differentiation | 0.65517509 |
| 70 | MP0002419_abnormal_innate_immunity | 0.65031489 |
| 71 | MP0005167_abnormal_blood-brain_barrier | 0.63992097 |
| 72 | MP0002735_abnormal_chemical_nociception | 0.63933072 |
| 73 | MP0000747_muscle_weakness | 0.62891359 |
| 74 | MP0001845_abnormal_inflammatory_respons | 0.62230851 |
| 75 | MP0005220_abnormal_exocrine_pancreas | 0.59088981 |
| 76 | MP0005666_abnormal_adipose_tissue | 0.57326279 |
| 77 | MP0005448_abnormal_energy_balance | 0.57235989 |
| 78 | MP0000627_abnormal_mammary_gland | 0.57087543 |
| 79 | MP0001501_abnormal_sleep_pattern | 0.56822157 |
| 80 | MP0001765_abnormal_ion_homeostasis | 0.56610719 |
| 81 | MP0000920_abnormal_myelination | 0.54952942 |
| 82 | MP0004510_myositis | 0.53750885 |
| 83 | MP0002019_abnormal_tumor_incidence | 0.51091832 |
| 84 | MP0003011_delayed_dark_adaptation | 0.50720591 |
| 85 | MP0000613_abnormal_salivary_gland | 0.49991840 |
| 86 | MP0005464_abnormal_platelet_physiology | 0.49956396 |
| 87 | MP0001764_abnormal_homeostasis | 0.48668545 |
| 88 | MP0004808_abnormal_hematopoietic_stem | 0.47442052 |
| 89 | MP0003705_abnormal_hypodermis_morpholog | 0.45228461 |
| 90 | MP0001664_abnormal_digestion | 0.44047741 |
| 91 | MP0009053_abnormal_anal_canal | 0.43697365 |
| 92 | MP0001944_abnormal_pancreas_morphology | 0.43644128 |
| 93 | MP0002653_abnormal_ependyma_morphology | 0.43065674 |
| 94 | MP0002160_abnormal_reproductive_system | 0.42788280 |
| 95 | MP0010234_abnormal_vibrissa_follicle | 0.42254306 |
| 96 | MP0008469_abnormal_protein_level | 0.41570752 |
| 97 | MP0005636_abnormal_mineral_homeostasis | 0.40880223 |
| 98 | MP0002163_abnormal_gland_morphology | 0.39942745 |
| 99 | MP0001145_abnormal_male_reproductive | 0.38767976 |
| 100 | MP0003303_peritoneal_inflammation | 0.37838508 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Testicular atrophy (HP:0000029) | 9.13132486 |
| 2 | Prostate neoplasm (HP:0100787) | 8.52554234 |
| 3 | Abnormality of the axillary hair (HP:0100134) | 7.51485453 |
| 4 | Abnormality of secondary sexual hair (HP:0009888) | 7.51485453 |
| 5 | Calf muscle hypertrophy (HP:0008981) | 7.42591337 |
| 6 | Gonadotropin excess (HP:0000837) | 6.87805168 |
| 7 | Muscle hypertrophy of the lower extremities (HP:0008968) | 6.53334955 |
| 8 | Abnormality of the prostate (HP:0008775) | 5.64817322 |
| 9 | Azoospermia (HP:0000027) | 5.23237659 |
| 10 | Abnormality of the 1st metacarpal (HP:0010009) | 5.11346227 |
| 11 | Short 1st metacarpal (HP:0010034) | 4.88206675 |
| 12 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 4.88206675 |
| 13 | Abnormal tarsal ossification (HP:0008369) | 4.63410359 |
| 14 | Abnormal spermatogenesis (HP:0008669) | 4.62517529 |
| 15 | T lymphocytopenia (HP:0005403) | 4.43891475 |
| 16 | Abnormality of T cell number (HP:0011839) | 4.32305334 |
| 17 | Testicular neoplasm (HP:0010788) | 4.19086288 |
| 18 | Septate vagina (HP:0001153) | 3.99091130 |
| 19 | Short phalanx of the thumb (HP:0009660) | 3.88894694 |
| 20 | Abnormality of carpal bone ossification (HP:0006257) | 3.79080143 |
| 21 | Abnormal foot bone ossification (HP:0010675) | 3.67302067 |
| 22 | Abnormality of male internal genitalia (HP:0000022) | 3.63083872 |
| 23 | Autoimmune hemolytic anemia (HP:0001890) | 3.26070124 |
| 24 | Ureteral stenosis (HP:0000071) | 3.21508168 |
| 25 | Bifid scrotum (HP:0000048) | 3.19946171 |
| 26 | Abnormal hand bone ossification (HP:0010660) | 3.12256749 |
| 27 | Bulbar palsy (HP:0001283) | 3.10906640 |
| 28 | Hyperpituitarism (HP:0010514) | 3.08526876 |
| 29 | Ureteral obstruction (HP:0006000) | 3.07277844 |
| 30 | Abnormality of T cells (HP:0002843) | 3.00139605 |
| 31 | Abnormal ossification of hand bones (HP:0005921) | 2.90599242 |
| 32 | Severe combined immunodeficiency (HP:0004430) | 2.89032632 |
| 33 | Aplastic anemia (HP:0001915) | 2.81822464 |
| 34 | Absent hair (HP:0002298) | 2.76008593 |
| 35 | Abnormality of the parathyroid morphology (HP:0011766) | 2.75027299 |
| 36 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 2.73129322 |
| 37 | 11 pairs of ribs (HP:0000878) | 2.67801364 |
| 38 | Flat acetabular roof (HP:0003180) | 2.61538762 |
| 39 | Growth hormone excess (HP:0000845) | 2.48189989 |
| 40 | Joint swelling (HP:0001386) | 2.46215757 |
| 41 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.38387046 |
| 42 | Abnormality of the calf musculature (HP:0001430) | 2.38077540 |
| 43 | Autoimmune thrombocytopenia (HP:0001973) | 2.36697647 |
| 44 | IgG deficiency (HP:0004315) | 2.29790020 |
| 45 | Recurrent fungal infections (HP:0002841) | 2.22788538 |
| 46 | Menstrual irregularities (HP:0000858) | 2.22617496 |
| 47 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.15856115 |
| 48 | Recurrent cutaneous fungal infections (HP:0011370) | 2.15856115 |
| 49 | Renal cortical cysts (HP:0000803) | 2.15813457 |
| 50 | Combined immunodeficiency (HP:0005387) | 2.11330261 |
| 51 | Hypoplasia of the thymus (HP:0000778) | 2.08802244 |
| 52 | Seborrheic dermatitis (HP:0001051) | 2.07555855 |
| 53 | Abnormality of the fingertips (HP:0001211) | 2.06657859 |
| 54 | Impaired smooth pursuit (HP:0007772) | 2.04980770 |
| 55 | Encephalitis (HP:0002383) | 2.03668145 |
| 56 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.01884503 |
| 57 | Spontaneous abortion (HP:0005268) | 1.99885322 |
| 58 | Abnormality of eosinophils (HP:0001879) | 1.97928526 |
| 59 | Gaze-evoked nystagmus (HP:0000640) | 1.97454746 |
| 60 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.96498227 |
| 61 | Recurrent viral infections (HP:0004429) | 1.94615197 |
| 62 | Gastrointestinal inflammation (HP:0004386) | 1.91864589 |
| 63 | Dysdiadochokinesis (HP:0002075) | 1.91746924 |
| 64 | Abnormality of T cell physiology (HP:0011840) | 1.88489349 |
| 65 | Dysmetric saccades (HP:0000641) | 1.82750871 |
| 66 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.82017153 |
| 67 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.81188612 |
| 68 | Thyroiditis (HP:0100646) | 1.80534832 |
| 69 | Female pseudohermaphroditism (HP:0010458) | 1.77769730 |
| 70 | Obstructive lung disease (HP:0006536) | 1.77492792 |
| 71 | Chronic obstructive pulmonary disease (HP:0006510) | 1.77492792 |
| 72 | Leukocytosis (HP:0001974) | 1.77405937 |
| 73 | Chronic diarrhea (HP:0002028) | 1.77328590 |
| 74 | Mediastinal lymphadenopathy (HP:0100721) | 1.75970281 |
| 75 | Microretrognathia (HP:0000308) | 1.73578624 |
| 76 | Deep palmar crease (HP:0006191) | 1.71759749 |
| 77 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.70679648 |
| 78 | Spontaneous hematomas (HP:0007420) | 1.70002547 |
| 79 | Neoplasm of the adrenal cortex (HP:0100641) | 1.69907727 |
| 80 | Abnormality of the 2nd finger (HP:0004100) | 1.67412428 |
| 81 | Broad face (HP:0000283) | 1.66589024 |
| 82 | Recurrent bronchitis (HP:0002837) | 1.64799251 |
| 83 | Stomatitis (HP:0010280) | 1.62795274 |
| 84 | Male pseudohermaphroditism (HP:0000037) | 1.62714823 |
| 85 | Radial bowing (HP:0002986) | 1.62708453 |
| 86 | Erectile abnormalities (HP:0100639) | 1.59776846 |
| 87 | Meningitis (HP:0001287) | 1.58387906 |
| 88 | Hypoproteinemia (HP:0003075) | 1.57467613 |
| 89 | Lower limb hyperreflexia (HP:0002395) | 1.56856586 |
| 90 | Gastrointestinal infarctions (HP:0005244) | 1.54274680 |
| 91 | Infertility (HP:0000789) | 1.53763060 |
| 92 | Vasculitis (HP:0002633) | 1.52177832 |
| 93 | Hyperthyroidism (HP:0000836) | 1.50658710 |
| 94 | Optic neuritis (HP:0100653) | 1.49391810 |
| 95 | Retrobulbar optic neuritis (HP:0100654) | 1.49391810 |
| 96 | Myokymia (HP:0002411) | 1.47966142 |
| 97 | Eczematoid dermatitis (HP:0000976) | 1.47764076 |
| 98 | Short 5th finger (HP:0009237) | 1.47626767 |
| 99 | Anorexia (HP:0002039) | 1.46887586 |
| 100 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.45133560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TNK2 | 8.20729541 |
| 2 | TAOK1 | 5.54514390 |
| 3 | CAMK1D | 5.10526213 |
| 4 | CAMK1G | 3.71884527 |
| 5 | FER | 3.53055921 |
| 6 | TESK2 | 3.20485027 |
| 7 | PIM2 | 3.19989829 |
| 8 | TXK | 2.80223973 |
| 9 | ARAF | 2.47709842 |
| 10 | MAP4K1 | 2.08208909 |
| 11 | MARK2 | 2.03940229 |
| 12 | RIPK4 | 2.00852349 |
| 13 | AKT3 | 1.99574001 |
| 14 | PRKD2 | 1.97089231 |
| 15 | RAF1 | 1.69598469 |
| 16 | ACVR1B | 1.69424602 |
| 17 | FES | 1.61527258 |
| 18 | TRIB3 | 1.55094860 |
| 19 | PRKCI | 1.36015081 |
| 20 | IRAK2 | 1.32794039 |
| 21 | MAP3K11 | 1.31985759 |
| 22 | IRAK3 | 1.06165251 |
| 23 | BRAF | 1.05922459 |
| 24 | ILK | 1.04934048 |
| 25 | CAMKK2 | 1.03739849 |
| 26 | CSK | 1.02798219 |
| 27 | GRK7 | 0.96007133 |
| 28 | EEF2K | 0.91448561 |
| 29 | PRKD3 | 0.89792726 |
| 30 | CDK7 | 0.89078638 |
| 31 | SMG1 | 0.87974154 |
| 32 | NLK | 0.85299237 |
| 33 | TESK1 | 0.81905646 |
| 34 | ERN1 | 0.80515199 |
| 35 | RPS6KA4 | 0.79790176 |
| 36 | ITK | 0.76377525 |
| 37 | TEC | 0.72281229 |
| 38 | MATK | 0.67534491 |
| 39 | LRRK2 | 0.63928322 |
| 40 | TAOK3 | 0.60418792 |
| 41 | IRAK4 | 0.59226076 |
| 42 | PIM1 | 0.58372359 |
| 43 | CDK12 | 0.57677792 |
| 44 | BTK | 0.56866708 |
| 45 | KDR | 0.53354974 |
| 46 | NUAK1 | 0.52670536 |
| 47 | GRK6 | 0.52478369 |
| 48 | STK11 | 0.51428746 |
| 49 | CSF1R | 0.50032038 |
| 50 | BCR | 0.49000631 |
| 51 | MAP2K2 | 0.48967947 |
| 52 | AURKA | 0.48627547 |
| 53 | MAP2K3 | 0.47443246 |
| 54 | JAK1 | 0.47337655 |
| 55 | CAMKK1 | 0.46062550 |
| 56 | CAMK1 | 0.45912479 |
| 57 | BMPR2 | 0.45409402 |
| 58 | MAP3K3 | 0.45249008 |
| 59 | PDK1 | 0.43885954 |
| 60 | TAOK2 | 0.42784157 |
| 61 | STK10 | 0.42597549 |
| 62 | CDK3 | 0.42164041 |
| 63 | LCK | 0.41359333 |
| 64 | BCKDK | 0.39983612 |
| 65 | MAPKAPK3 | 0.37956557 |
| 66 | MTOR | 0.36409261 |
| 67 | PRKD1 | 0.35435603 |
| 68 | MOS | 0.35210273 |
| 69 | PRKAA2 | 0.35185568 |
| 70 | SYK | 0.34582911 |
| 71 | FGR | 0.34567298 |
| 72 | DAPK1 | 0.34061926 |
| 73 | MAP2K6 | 0.31816719 |
| 74 | TGFBR2 | 0.30682576 |
| 75 | LYN | 0.30514471 |
| 76 | BLK | 0.30104176 |
| 77 | SGK223 | 0.29986040 |
| 78 | SGK494 | 0.29986040 |
| 79 | SIK2 | 0.28921427 |
| 80 | HCK | 0.28151843 |
| 81 | ZAP70 | 0.25158527 |
| 82 | BRSK2 | 0.25095649 |
| 83 | SGK3 | 0.24088154 |
| 84 | MARK3 | 0.23075104 |
| 85 | PDPK1 | 0.23066070 |
| 86 | PRKCQ | 0.22902445 |
| 87 | DAPK2 | 0.22512358 |
| 88 | GRK5 | 0.21359505 |
| 89 | IRAK1 | 0.20849346 |
| 90 | SGK2 | 0.19878264 |
| 91 | IKBKE | 0.19485896 |
| 92 | YES1 | 0.19039898 |
| 93 | MAPK8 | 0.17713292 |
| 94 | MAPK11 | 0.17246068 |
| 95 | PRKCZ | 0.17154765 |
| 96 | SIK3 | 0.16633861 |
| 97 | PRKAA1 | 0.16513019 |
| 98 | MAP3K14 | 0.16410079 |
| 99 | PDGFRB | 0.15378619 |
| 100 | CLK1 | 0.15240294 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 5.78500921 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.94645160 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.66979122 |
| 4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.55388866 |
| 5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.77010280 |
| 6 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.69970948 |
| 7 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.48582178 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.19496757 |
| 9 | Prostate cancer_Homo sapiens_hsa05215 | 2.15833383 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.13477870 |
| 11 | Measles_Homo sapiens_hsa05162 | 1.76490610 |
| 12 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.72588513 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.71898515 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57613159 |
| 15 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.47694964 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.34438432 |
| 17 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.30179357 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.28588103 |
| 19 | Thyroid cancer_Homo sapiens_hsa05216 | 1.22589991 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21639822 |
| 21 | Platelet activation_Homo sapiens_hsa04611 | 1.21479945 |
| 22 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.17557878 |
| 23 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.16593056 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.14174920 |
| 25 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.12460425 |
| 26 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.11088769 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.10897685 |
| 28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.10860426 |
| 29 | Colorectal cancer_Homo sapiens_hsa05210 | 1.06349937 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.03857813 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.03012093 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.02376797 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 0.99696267 |
| 34 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.97760109 |
| 35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.96848644 |
| 36 | Renin secretion_Homo sapiens_hsa04924 | 0.93309617 |
| 37 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.91262361 |
| 38 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.90742471 |
| 39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.90449540 |
| 40 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.89294195 |
| 41 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.89141270 |
| 42 | Ribosome_Homo sapiens_hsa03010 | 0.87117736 |
| 43 | Endometrial cancer_Homo sapiens_hsa05213 | 0.83540852 |
| 44 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.83363408 |
| 45 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.81072303 |
| 46 | Leishmaniasis_Homo sapiens_hsa05140 | 0.77189151 |
| 47 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.76457190 |
| 48 | Long-term potentiation_Homo sapiens_hsa04720 | 0.75556752 |
| 49 | Hepatitis B_Homo sapiens_hsa05161 | 0.75350772 |
| 50 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.75277948 |
| 51 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.73278910 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.72556411 |
| 53 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.69455022 |
| 54 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.68795900 |
| 55 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.67450827 |
| 56 | RNA polymerase_Homo sapiens_hsa03020 | 0.66770847 |
| 57 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.66396108 |
| 58 | Endocytosis_Homo sapiens_hsa04144 | 0.66094781 |
| 59 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.65290454 |
| 60 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64955899 |
| 61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.64595755 |
| 62 | Influenza A_Homo sapiens_hsa05164 | 0.64585030 |
| 63 | Hepatitis C_Homo sapiens_hsa05160 | 0.64069946 |
| 64 | Salmonella infection_Homo sapiens_hsa05132 | 0.64021402 |
| 65 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.63493041 |
| 66 | Lysine degradation_Homo sapiens_hsa00310 | 0.63461301 |
| 67 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.63400009 |
| 68 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.63300026 |
| 69 | Malaria_Homo sapiens_hsa05144 | 0.61497437 |
| 70 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.61346734 |
| 71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.61287558 |
| 72 | Insulin resistance_Homo sapiens_hsa04931 | 0.60623794 |
| 73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60188485 |
| 74 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.58587930 |
| 75 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.58377892 |
| 76 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.56737396 |
| 77 | Tuberculosis_Homo sapiens_hsa05152 | 0.55752672 |
| 78 | Peroxisome_Homo sapiens_hsa04146 | 0.55589776 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53072977 |
| 80 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52452196 |
| 81 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.51452746 |
| 82 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50864374 |
| 83 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.50714189 |
| 84 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.49078786 |
| 85 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.48729166 |
| 86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47747766 |
| 87 | HTLV-I infection_Homo sapiens_hsa05166 | 0.46718749 |
| 88 | RNA degradation_Homo sapiens_hsa03018 | 0.44083220 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.43587777 |
| 90 | Nicotine addiction_Homo sapiens_hsa05033 | 0.42579628 |
| 91 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.42014426 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41921063 |
| 93 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.40652323 |
| 94 | Spliceosome_Homo sapiens_hsa03040 | 0.39711979 |
| 95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.39246474 |
| 96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.38980467 |
| 97 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.35440367 |
| 98 | Pathways in cancer_Homo sapiens_hsa05200 | 0.35153662 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34476352 |
| 100 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.34072685 |

