TRIAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.48694270
2DNA deamination (GO:0045006)5.15981805
3proteasome assembly (GO:0043248)5.11786658
4ribosomal small subunit biogenesis (GO:0042274)4.68983259
5viral transcription (GO:0019083)4.66777046
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.56960321
7transcription elongation from RNA polymerase III promoter (GO:0006385)4.53953392
8termination of RNA polymerase III transcription (GO:0006386)4.53953392
9translational termination (GO:0006415)4.53743740
10cotranslational protein targeting to membrane (GO:0006613)4.49158805
11chromatin remodeling at centromere (GO:0031055)4.47901512
12protein targeting to ER (GO:0045047)4.45033005
13negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.43662470
14CENP-A containing nucleosome assembly (GO:0034080)4.43576370
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.39075950
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:4.38344575
17maturation of SSU-rRNA (GO:0030490)4.35656686
18establishment of integrated proviral latency (GO:0075713)4.34835023
19regulation of cellular amino acid metabolic process (GO:0006521)4.33946934
20protein localization to endoplasmic reticulum (GO:0070972)4.29790701
21positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.22243320
22establishment of protein localization to endoplasmic reticulum (GO:0072599)4.21876244
23antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)4.21581024
24mitotic metaphase plate congression (GO:0007080)4.18432927
25energy coupled proton transport, down electrochemical gradient (GO:0015985)4.14139027
26ATP synthesis coupled proton transport (GO:0015986)4.14139027
27translational elongation (GO:0006414)4.06249980
28regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.05717522
297-methylguanosine mRNA capping (GO:0006370)4.02345412
30negative regulation of ligase activity (GO:0051352)4.00909569
31negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.00909569
32* DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.00386829
33ribosomal large subunit biogenesis (GO:0042273)3.96467145
34anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.94949410
35regulation of mitochondrial translation (GO:0070129)3.93767690
36formation of translation preinitiation complex (GO:0001731)3.93022433
37chaperone-mediated protein transport (GO:0072321)3.92309118
38ribosome assembly (GO:0042255)3.92203058
39translation (GO:0006412)3.91979261
407-methylguanosine RNA capping (GO:0009452)3.91722950
41RNA capping (GO:0036260)3.91722950
42* intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.90916015
43* signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.90916015
44* signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.90098363
45* signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.90098363
46* signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.90098363
47translational initiation (GO:0006413)3.86387565
48protein deneddylation (GO:0000338)3.85243660
49* signal transduction involved in DNA integrity checkpoint (GO:0072401)3.77140784
50* signal transduction involved in DNA damage checkpoint (GO:0072422)3.77140784
51L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.76636694
52viral life cycle (GO:0019058)3.75906782
53exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.75647630
54cullin deneddylation (GO:0010388)3.73252169
55nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.72606419
56* signal transduction involved in cell cycle checkpoint (GO:0072395)3.72089311
57histone exchange (GO:0043486)3.70453287
58deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.70382988
59positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.62763974
60cellular protein complex disassembly (GO:0043624)3.61725013
61metaphase plate congression (GO:0051310)3.61616406
62protein neddylation (GO:0045116)3.55975730
63antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.54238080
64DNA replication checkpoint (GO:0000076)3.51398163
65spliceosomal snRNP assembly (GO:0000387)3.50995757
66positive regulation of ligase activity (GO:0051351)3.47992619
67DNA replication-independent nucleosome organization (GO:0034724)3.47423485
68DNA replication-independent nucleosome assembly (GO:0006336)3.47423485
69DNA double-strand break processing (GO:0000729)3.42662426
70rRNA modification (GO:0000154)3.41646435
71establishment of viral latency (GO:0019043)3.40624993
72protein localization to kinetochore (GO:0034501)3.39524665
73DNA strand elongation (GO:0022616)3.36845315
74ribonucleoprotein complex biogenesis (GO:0022613)3.36630316
75nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.35533911
76attachment of spindle microtubules to kinetochore (GO:0008608)3.35131587
77IMP biosynthetic process (GO:0006188)3.35090703
78purine nucleobase biosynthetic process (GO:0009113)3.33950741
79DNA catabolic process, exonucleolytic (GO:0000738)3.32483644
80L-methionine biosynthetic process (GO:0071265)3.31991932
81amino acid salvage (GO:0043102)3.31991932
82L-methionine salvage (GO:0071267)3.31991932
83peptidyl-histidine modification (GO:0018202)3.27703023
84GDP-mannose metabolic process (GO:0019673)3.27673284
85rRNA methylation (GO:0031167)3.27506118
86DNA ligation (GO:0006266)3.24970967
87RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24783325
88tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24783325
89signal peptide processing (GO:0006465)3.24191528
90DNA damage response, detection of DNA damage (GO:0042769)3.22731392
91mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.22167720
92guanosine-containing compound biosynthetic process (GO:1901070)3.21245036
93protein targeting to mitochondrion (GO:0006626)3.20451632
94transcription from mitochondrial promoter (GO:0006390)3.18443392
95cellular component biogenesis (GO:0044085)3.15914898
96nucleobase biosynthetic process (GO:0046112)3.15850217
97regulation of cellular amine metabolic process (GO:0033238)3.15409838
98establishment of protein localization to mitochondrial membrane (GO:0090151)3.14755575
99respiratory chain complex IV assembly (GO:0008535)3.14699095
100protein complex biogenesis (GO:0070271)3.14615596
101transcription from RNA polymerase I promoter (GO:0006360)3.12716819
102respiratory electron transport chain (GO:0022904)3.10860924
103establishment of protein localization to mitochondrion (GO:0072655)3.10782066
104maturation of 5.8S rRNA (GO:0000460)3.09954514
105rRNA processing (GO:0006364)3.08984686
106oxidative phosphorylation (GO:0006119)3.08561080
107transcription-coupled nucleotide-excision repair (GO:0006283)3.08283162
108mitochondrial respiratory chain complex I assembly (GO:0032981)3.08197621
109NADH dehydrogenase complex assembly (GO:0010257)3.08197621
110mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.08197621
111regulation of ubiquitin-protein transferase activity (GO:0051438)3.08002835
112histone mRNA metabolic process (GO:0008334)3.07577596
113nucleobase-containing small molecule interconversion (GO:0015949)3.06988247
114iron-sulfur cluster assembly (GO:0016226)3.06551924
115metallo-sulfur cluster assembly (GO:0031163)3.06551924
116tRNA aminoacylation (GO:0043039)3.05826340
117amino acid activation (GO:0043038)3.05826340
118protein localization to mitochondrion (GO:0070585)3.05152776
119termination of RNA polymerase I transcription (GO:0006363)3.04654162
120tRNA aminoacylation for protein translation (GO:0006418)3.04038603
121DNA replication-dependent nucleosome organization (GO:0034723)3.03280977
122DNA replication-dependent nucleosome assembly (GO:0006335)3.03280977
123electron transport chain (GO:0022900)3.02921635
124mitochondrial respiratory chain complex assembly (GO:0033108)3.01973730
125kinetochore organization (GO:0051383)3.01797148
126telomere maintenance via semi-conservative replication (GO:0032201)3.01033163
127telomere maintenance via recombination (GO:0000722)3.01013190
128* positive regulation of cell cycle arrest (GO:0071158)3.00842798
129DNA strand elongation involved in DNA replication (GO:0006271)3.00646335
130transcription elongation from RNA polymerase I promoter (GO:0006362)3.00084735
131inner mitochondrial membrane organization (GO:0007007)2.98730991
132regulation of ligase activity (GO:0051340)2.98044191
133G1/S transition of mitotic cell cycle (GO:0000082)2.97749509
134cell cycle G1/S phase transition (GO:0044843)2.97749509
135GTP biosynthetic process (GO:0006183)2.96603436
136pseudouridine synthesis (GO:0001522)2.96577779
137rRNA metabolic process (GO:0016072)2.95769759
138protein targeting to membrane (GO:0006612)2.94323716

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.70175928
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.55017516
3* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.14267260
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.10444899
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.78020714
6* ETS1_20019798_ChIP-Seq_JURKAT_Human3.68748929
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.66920395
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.56218490
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.50284831
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.24690142
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.22140001
12E2F7_22180533_ChIP-Seq_HELA_Human3.05636196
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91810099
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.82692647
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.78551287
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.76790482
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.74543568
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.70794936
19* VDR_23849224_ChIP-Seq_CD4+_Human2.67882330
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53589453
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.50124013
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.44985949
23* DCP1A_22483619_ChIP-Seq_HELA_Human2.32825834
24FOXM1_23109430_ChIP-Seq_U2OS_Human2.29722303
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.29279338
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.25092879
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.13813223
28FOXP3_21729870_ChIP-Seq_TREG_Human2.13418188
29* XRN2_22483619_ChIP-Seq_HELA_Human2.13157729
30NELFA_20434984_ChIP-Seq_ESCs_Mouse2.11794668
31ELK1_19687146_ChIP-ChIP_HELA_Human2.10660871
32GABP_19822575_ChIP-Seq_HepG2_Human2.10420010
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.01154762
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.99733489
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.95189846
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.94770750
37HOXB4_20404135_ChIP-ChIP_EML_Mouse1.84512693
38E2F4_17652178_ChIP-ChIP_JURKAT_Human1.76299861
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76195391
40* TTF2_22483619_ChIP-Seq_HELA_Human1.76133056
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.72371703
42IRF8_21731497_ChIP-ChIP_J774_Mouse1.69703022
43KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.69119346
44FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.68346158
45* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.65266276
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.58869213
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.55058168
48ELK1_22589737_ChIP-Seq_MCF10A_Human1.53949106
49* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.52925456
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52593464
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.48437388
52* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.44926366
53* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.43717931
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43304551
55CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.42778711
56IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.39531200
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.38724969
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.30809802
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.30181566
60* SPI1_23547873_ChIP-Seq_NB4_Human1.29757863
61EWS_26573619_Chip-Seq_HEK293_Human1.27373775
62NANOG_16153702_ChIP-ChIP_HESCs_Human1.27260457
63CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.27200314
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.26013587
65ZNF274_21170338_ChIP-Seq_K562_Hela1.25794473
66ZFX_18555785_ChIP-Seq_MESCs_Mouse1.25700330
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25056770
68IRF8_22096565_ChIP-ChIP_GC-B_Human1.23185034
69TFEB_21752829_ChIP-Seq_HELA_Human1.20825866
70YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15542253
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.14805839
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13166940
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11873129
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10242406
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.09277999
76SOX2_16153702_ChIP-ChIP_HESCs_Human1.08512164
77MYC_18940864_ChIP-ChIP_HL60_Human1.08083520
78FUS_26573619_Chip-Seq_HEK293_Human1.07702228
79MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.07387278
80CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.05549061
81* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.04172684
82HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.04029065
83BP1_19119308_ChIP-ChIP_Hs578T_Human1.02679562
84CIITA_25753668_ChIP-Seq_RAJI_Human1.01616829
85FLI1_27457419_Chip-Seq_LIVER_Mouse0.99676296
86KDM5A_27292631_Chip-Seq_BREAST_Human0.97281848
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97186839
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97038721
89STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96826822
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96268088
91STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95561520
92POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.94815991
93FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93619526
94KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92139188
95VDR_22108803_ChIP-Seq_LS180_Human0.91564025
96* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91055264
97* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.90674541
98CTCF_18555785_ChIP-Seq_MESCs_Mouse0.90591331
99AR_21909140_ChIP-Seq_LNCAP_Human0.89446491
100* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.89323949
101HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88204011
102* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87022663
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.86988070
104E2F1_21310950_ChIP-Seq_MCF-7_Human0.86173818
105* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.84717285
106EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.84698415
107NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.82912652
108NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81893326
109STAT4_19710469_ChIP-ChIP_TH1__Mouse0.81788361
110SOX17_20123909_ChIP-Seq_XEN_Mouse0.81253417
111ELF5_23300383_ChIP-Seq_T47D_Human0.80837595
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.80767746
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.79534272
114* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.77465035
115SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77165725
116PU.1_20513432_ChIP-Seq_Bcells_Mouse0.77130756
117IRF1_19129219_ChIP-ChIP_H3396_Human0.75861529
118PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.75666906
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.73331955
120TP63_19390658_ChIP-ChIP_HaCaT_Human0.72207546
121KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.70726788
122PCGF2_27294783_Chip-Seq_ESCs_Mouse0.66924023
123NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.65312249
124EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.64651045

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.84686005
2MP0003186_abnormal_redox_activity2.98451564
3MP0004957_abnormal_blastocyst_morpholog2.97863900
4MP0006292_abnormal_olfactory_placode2.72507457
5MP0003806_abnormal_nucleotide_metabolis2.68197552
6MP0009379_abnormal_foot_pigmentation2.67576386
7MP0008260_abnormal_autophagy2.64692348
8MP0003718_maternal_effect2.63113449
9MP0008789_abnormal_olfactory_epithelium2.50284410
10MP0001835_abnormal_antigen_presentation2.44495496
11MP0010094_abnormal_chromosome_stability2.43239159
12MP0005058_abnormal_lysosome_morphology2.42145400
13MP0005451_abnormal_body_composition2.41342968
14MP0008058_abnormal_DNA_repair2.35104909
15MP0002132_abnormal_respiratory_system2.24857917
16MP0009333_abnormal_splenocyte_physiolog2.20907617
17MP0008877_abnormal_DNA_methylation2.18445821
18MP0006036_abnormal_mitochondrial_physio2.16636545
19MP0009785_altered_susceptibility_to2.15009094
20MP0003111_abnormal_nucleus_morphology2.13574255
21MP0002148_abnormal_hypersensitivity_rea2.12271377
22MP0003077_abnormal_cell_cycle2.11019725
23MP0009840_abnormal_foam_cell2.03773526
24MP0002277_abnormal_respiratory_mucosa2.00067850
25MP0001986_abnormal_taste_sensitivity1.95530403
26MP0001293_anophthalmia1.90149288
27MP0008007_abnormal_cellular_replicative1.83549600
28MP0008932_abnormal_embryonic_tissue1.81711561
29MP0003724_increased_susceptibility_to1.78647113
30MP0002396_abnormal_hematopoietic_system1.71288276
31MP0005671_abnormal_response_to1.70534122
32MP0001542_abnormal_bone_strength1.66590729
33MP0004147_increased_porphyrin_level1.65639937
34MP0002938_white_spotting1.64768446
35MP0002102_abnormal_ear_morphology1.64518831
36MP0005499_abnormal_olfactory_system1.64085475
37MP0005394_taste/olfaction_phenotype1.64085475
38MP0006035_abnormal_mitochondrial_morpho1.63333585
39MP0001764_abnormal_homeostasis1.62971719
40MP0003656_abnormal_erythrocyte_physiolo1.61018759
41MP0003786_premature_aging1.60431582
42MP0005025_abnormal_response_to1.57456559
43MP0005000_abnormal_immune_tolerance1.55580129
44MP0006072_abnormal_retinal_apoptosis1.52412162
45MP0000858_altered_metastatic_potential1.47121575
46MP0003195_calcinosis1.46783160
47MP0002419_abnormal_innate_immunity1.45739004
48MP0005075_abnormal_melanosome_morpholog1.41618538
49MP0003436_decreased_susceptibility_to1.38788681
50MP0001697_abnormal_embryo_size1.37949234
51MP0004782_abnormal_surfactant_physiolog1.34813438
52MP0005174_abnormal_tail_pigmentation1.33287907
53MP0004381_abnormal_hair_follicle1.30949842
54MP0000015_abnormal_ear_pigmentation1.30796466
55MP0002723_abnormal_immune_serum1.30072678
56MP0009697_abnormal_copulation1.29920462
57MP0002452_abnormal_antigen_presenting1.29295295
58MP0005083_abnormal_biliary_tract1.28069802
59MP0000358_abnormal_cell_content/1.27503743
60MP0002420_abnormal_adaptive_immunity1.27106532
61MP0001819_abnormal_immune_cell1.26523446
62MP0010030_abnormal_orbit_morphology1.25522652
63MP0000490_abnormal_crypts_of1.25365586
64MP0005367_renal/urinary_system_phenotyp1.24456115
65MP0000516_abnormal_urinary_system1.24456115
66MP0003937_abnormal_limbs/digits/tail_de1.20952516
67MP0008469_abnormal_protein_level1.19456490
68MP0001672_abnormal_embryogenesis/_devel1.19249519
69MP0005380_embryogenesis_phenotype1.19249519
70MP0001853_heart_inflammation1.19018001
71MP0003763_abnormal_thymus_physiology1.18981995
72MP0005408_hypopigmentation1.18667994
73MP0001529_abnormal_vocalization1.18606053
74MP0002085_abnormal_embryonic_tissue1.18376988
75MP0002233_abnormal_nose_morphology1.18069336
76MP0000372_irregular_coat_pigmentation1.17606447
77MP0002234_abnormal_pharynx_morphology1.17368720
78MP0003890_abnormal_embryonic-extraembry1.17268424
79MP0002876_abnormal_thyroid_physiology1.17209413
80MP0002693_abnormal_pancreas_physiology1.17126928
81MP0001800_abnormal_humoral_immune1.16588577
82MP0003567_abnormal_fetal_cardiomyocyte1.15762979
83MP0000689_abnormal_spleen_morphology1.15045824
84MP0002210_abnormal_sex_determination1.13753470
85MP0000685_abnormal_immune_system1.12862044
86MP0005084_abnormal_gallbladder_morpholo1.12717519
87MP0003121_genomic_imprinting1.12357959
88MP0006082_CNS_inflammation1.12266157
89MP0002090_abnormal_vision1.11761237
90MP0002398_abnormal_bone_marrow1.10866358
91MP0002095_abnormal_skin_pigmentation1.10793442
92MP0005636_abnormal_mineral_homeostasis1.10449291
93MP0002080_prenatal_lethality1.09917732
94MP0000049_abnormal_middle_ear1.08867917
95MP0001845_abnormal_inflammatory_respons1.08413022
96MP0002084_abnormal_developmental_patter1.08077460
97MP0001286_abnormal_eye_development1.07241682
98MP0002722_abnormal_immune_system1.07222609
99MP0003221_abnormal_cardiomyocyte_apopto1.06944513
100MP0010386_abnormal_urinary_bladder1.06593260
101MP0002638_abnormal_pupillary_reflex1.06565618
102MP0002429_abnormal_blood_cell1.05064883
103MP0002405_respiratory_system_inflammati1.04321920
104MP0002019_abnormal_tumor_incidence1.03880536
105MP0000716_abnormal_immune_system1.03455526
106MP0003011_delayed_dark_adaptation1.01920906
107MP0003941_abnormal_skin_development1.01717785
108MP0002736_abnormal_nociception_after1.01522002
109MP0001929_abnormal_gametogenesis1.00647872
110MP0002163_abnormal_gland_morphology0.99422706
111MP0003119_abnormal_digestive_system0.97273951
112MP0003984_embryonic_growth_retardation0.96687444
113MP0001145_abnormal_male_reproductive0.96609458
114MP0002796_impaired_skin_barrier0.96439523
115MP0003315_abnormal_perineum_morphology0.96012489
116MP0000653_abnormal_sex_gland0.95170197
117MP0005387_immune_system_phenotype0.94610188
118MP0001790_abnormal_immune_system0.94610188
119MP0002160_abnormal_reproductive_system0.94556010
120MP0005464_abnormal_platelet_physiology0.94236985
121MP0002697_abnormal_eye_size0.94141138
122MP0002088_abnormal_embryonic_growth/wei0.93836641
123MP0003950_abnormal_plasma_membrane0.93827103
124MP0004133_heterotaxia0.93822241
125MP0010307_abnormal_tumor_latency0.91459864
126MP0009672_abnormal_birth_weight0.91291698
127MP0002751_abnormal_autonomic_nervous0.90169337
128MP0000537_abnormal_urethra_morphology0.89866221
129MP0008995_early_reproductive_senescence0.86022356
130MP0009643_abnormal_urine_homeostasis0.85852927
131MP0008057_abnormal_DNA_replication0.85782147
132MP0003136_yellow_coat_color0.85290968
133MP0005253_abnormal_eye_physiology0.84936546
134MP0002111_abnormal_tail_morphology0.84300870
135MP0000313_abnormal_cell_death0.82663913
136MP0001485_abnormal_pinna_reflex0.82339293
137MP0000343_altered_response_to0.82249478
138MP0005397_hematopoietic_system_phenotyp0.81888364
139MP0001545_abnormal_hematopoietic_system0.81888364
140MP0004197_abnormal_fetal_growth/weight/0.80271563
141MP0005310_abnormal_salivary_gland0.80231172
142MP0000749_muscle_degeneration0.79910135
143MP0005379_endocrine/exocrine_gland_phen0.79467656
144MP0002282_abnormal_trachea_morphology0.78884620
145MP0001984_abnormal_olfaction0.78230935
146MP0005389_reproductive_system_phenotype0.77940214
147MP0005332_abnormal_amino_acid0.76926627
148MP0006054_spinal_hemorrhage0.76578486
149MP0000350_abnormal_cell_proliferation0.76334279
150MP0000647_abnormal_sebaceous_gland0.76061762
151MP0001730_embryonic_growth_arrest0.75303124
152MP0003123_paternal_imprinting0.74619432
153MP0001119_abnormal_female_reproductive0.73760684
154MP0009764_decreased_sensitivity_to0.73367042
155MP0003755_abnormal_palate_morphology0.73333004
156MP0001346_abnormal_lacrimal_gland0.70378935
157MP0005391_vision/eye_phenotype0.68523687
158MP0002254_reproductive_system_inflammat0.65777566
159MP0005395_other_phenotype0.64964398
160MP0009053_abnormal_anal_canal0.64789795
161MP0001919_abnormal_reproductive_system0.64613196

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.60313069
2Acute necrotizing encephalopathy (HP:0006965)4.45795335
3Abnormal number of erythroid precursors (HP:0012131)4.39542322
4Mitochondrial inheritance (HP:0001427)4.14455359
5Abnormal mitochondria in muscle tissue (HP:0008316)4.13399737
6Vacuolated lymphocytes (HP:0001922)4.11325383
7Hepatocellular necrosis (HP:0001404)3.97396527
8Hepatic necrosis (HP:0002605)3.86695884
9Acute encephalopathy (HP:0006846)3.77760832
10Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.72713718
11Decreased activity of mitochondrial respiratory chain (HP:0008972)3.72713718
12Increased CSF lactate (HP:0002490)3.63944051
133-Methylglutaconic aciduria (HP:0003535)3.63296141
14Reticulocytopenia (HP:0001896)3.51021494
15Progressive macrocephaly (HP:0004481)3.49205577
16Increased hepatocellular lipid droplets (HP:0006565)3.20779771
17Macrocytic anemia (HP:0001972)3.18274960
18Birth length less than 3rd percentile (HP:0003561)3.15175717
19Colon cancer (HP:0003003)3.09677093
20Lipid accumulation in hepatocytes (HP:0006561)3.07565735
21Abnormality of the labia minora (HP:0012880)3.07030863
22Type I transferrin isoform profile (HP:0003642)3.06824311
23Increased serum lactate (HP:0002151)3.05654554
24Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.99288845
25Meckel diverticulum (HP:0002245)2.87097371
26Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.86155967
27Abnormality of glycolysis (HP:0004366)2.85974680
28Increased serum pyruvate (HP:0003542)2.85974680
29Chromosomal breakage induced by crosslinking agents (HP:0003221)2.83537713
30Abnormality of methionine metabolism (HP:0010901)2.80017709
31Abnormality of placental membranes (HP:0011409)2.77875910
32Amniotic constriction ring (HP:0009775)2.77875910
33Chromsome breakage (HP:0040012)2.77657734
34Respiratory failure (HP:0002878)2.76427720
35Lactic acidosis (HP:0003128)2.75915644
36Cerebral hypomyelination (HP:0006808)2.74958060
37Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.74167836
38Abnormality of the ileum (HP:0001549)2.72523369
39Exertional dyspnea (HP:0002875)2.71408749
40Renal Fanconi syndrome (HP:0001994)2.70568500
41Pallor (HP:0000980)2.66131191
42Nausea (HP:0002018)2.62813371
43Breast hypoplasia (HP:0003187)2.62111696
44Abnormality of macrophages (HP:0004311)2.62051514
45Cerebral edema (HP:0002181)2.61622810
46Increased intramyocellular lipid droplets (HP:0012240)2.58653621
47Exercise intolerance (HP:0003546)2.57660943
48Abnormality of the preputium (HP:0100587)2.55731447
49Rough bone trabeculation (HP:0100670)2.54159334
50Abnormality of chromosome stability (HP:0003220)2.50877030
51Aplasia/Hypoplasia of the uvula (HP:0010293)2.47791648
52Methylmalonic acidemia (HP:0002912)2.40544755
53Respiratory difficulties (HP:0002880)2.40092356
54Poor head control (HP:0002421)2.39768912
55Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.39584798
56Abnormality of alanine metabolism (HP:0010916)2.39584798
57Hyperalaninemia (HP:0003348)2.39584798
58Increased muscle lipid content (HP:0009058)2.38919409
59Abnormality of serum amino acid levels (HP:0003112)2.38774742
60Congenital ichthyosiform erythroderma (HP:0007431)2.35941826
61IgM deficiency (HP:0002850)2.35735834
62Aplastic anemia (HP:0001915)2.34910967
63Abnormal lung lobation (HP:0002101)2.32402967
64Multiple enchondromatosis (HP:0005701)2.32277846
65Sparse eyelashes (HP:0000653)2.32102943
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.31520499
67Abnormal protein N-linked glycosylation (HP:0012347)2.31520499
68Abnormal protein glycosylation (HP:0012346)2.31520499
69Abnormal glycosylation (HP:0012345)2.31520499
70Leukodystrophy (HP:0002415)2.30601771
71Muscle fiber atrophy (HP:0100295)2.29683583
72Abnormality of aspartate family amino acid metabolism (HP:0010899)2.27329586
73Methylmalonic aciduria (HP:0012120)2.26232663
74CNS demyelination (HP:0007305)2.26048720
75Aplasia/Hypoplasia of the sacrum (HP:0008517)2.23800807
76Reduced antithrombin III activity (HP:0001976)2.21634239
77Degeneration of anterior horn cells (HP:0002398)2.21584994
78Abnormality of the anterior horn cell (HP:0006802)2.21584994
79Type 2 muscle fiber atrophy (HP:0003554)2.21193498
80Microvesicular hepatic steatosis (HP:0001414)2.18954042
81Recurrent abscess formation (HP:0002722)2.17791475
82Abnormal trabecular bone morphology (HP:0100671)2.13128626
83Lethargy (HP:0001254)2.08151792
84Triphalangeal thumb (HP:0001199)2.06202128
85Absent thumb (HP:0009777)2.05857384
86Duodenal stenosis (HP:0100867)2.05386612
87Small intestinal stenosis (HP:0012848)2.05386612
88Petechiae (HP:0000967)2.03438220
89Hepatosplenomegaly (HP:0001433)2.02981930
90Generalized aminoaciduria (HP:0002909)2.02452133
91Secondary amenorrhea (HP:0000869)2.02323986
92Microretrognathia (HP:0000308)2.01037262
93Hypoplastic pelvis (HP:0008839)2.00715152
94Death in infancy (HP:0001522)1.98931867
95Congenital, generalized hypertrichosis (HP:0004540)1.98927166
96Stenosis of the external auditory canal (HP:0000402)1.98839768
97Carpal bone hypoplasia (HP:0001498)1.98537762
98Oral leukoplakia (HP:0002745)1.98231823
99Megaloblastic anemia (HP:0001889)1.96736360
100Hypothermia (HP:0002045)1.96302553
101Neoplasm of the adrenal gland (HP:0100631)1.95492543
102Glycosuria (HP:0003076)1.95030312
103Abnormality of urine glucose concentration (HP:0011016)1.95030312
104Progressive external ophthalmoplegia (HP:0000590)1.92446085
105Abnormal hemoglobin (HP:0011902)1.91828926
106Parakeratosis (HP:0001036)1.91480779
107Sensory axonal neuropathy (HP:0003390)1.91312669
108Abnormality of the heme biosynthetic pathway (HP:0010472)1.89970034
109Pancytopenia (HP:0001876)1.89167548
110Abnormality of the duodenum (HP:0002246)1.88766873
111Progressive neurologic deterioration (HP:0002344)1.86355873
112Optic disc pallor (HP:0000543)1.86160017
113Beaking of vertebral bodies (HP:0004568)1.84994401
114Abnormality of serine family amino acid metabolism (HP:0010894)1.84350381
115Abnormality of glycine metabolism (HP:0010895)1.84350381
116Recurrent bacterial skin infections (HP:0005406)1.82778595
117Systemic lupus erythematosus (HP:0002725)1.81944701
118Prolonged neonatal jaundice (HP:0006579)1.81022423
119Abnormality of the axillary hair (HP:0100134)1.80704522
120Abnormality of secondary sexual hair (HP:0009888)1.80704522
121Myelodysplasia (HP:0002863)1.80442973
122Abnormality of renal resorption (HP:0011038)1.78881237
123Sloping forehead (HP:0000340)1.78734593
124Hyperglycinemia (HP:0002154)1.78283942
125Gliosis (HP:0002171)1.77840094
126Abnormalities of placenta or umbilical cord (HP:0001194)1.77793884
127Horseshoe kidney (HP:0000085)1.77169498
128Septo-optic dysplasia (HP:0100842)1.77045645
129Hyperglycinuria (HP:0003108)1.76662618
130Premature ovarian failure (HP:0008209)1.76060788
131Hyperinsulinemic hypoglycemia (HP:0000825)1.75851045
132Thrombocytosis (HP:0001894)1.74752112
133CNS hypomyelination (HP:0003429)1.74629906
134Aplasia/Hypoplasia involving the musculature (HP:0001460)1.74609345
135Abnormality of dicarboxylic acid metabolism (HP:0010995)1.74411124
136Dicarboxylic aciduria (HP:0003215)1.74411124
137Median cleft lip (HP:0000161)1.72633558
138Emotional lability (HP:0000712)1.72538741
139Elevated erythrocyte sedimentation rate (HP:0003565)1.72473067
140Irregular epiphyses (HP:0010582)1.71707773
141Spastic diplegia (HP:0001264)1.71030847

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.17897633
2STK164.13170298
3NME24.01001704
4BUB13.95039026
5EIF2AK13.37942155
6PIM22.98191539
7ARAF2.68079139
8WEE12.60459345
9EIF2AK32.28122731
10TRIM282.27084876
11NUAK12.12887319
12MAP3K122.01013219
13BLK1.97320486
14VRK11.95716360
15MST41.84014971
16TAF11.73286183
17PLK41.71429403
18ACVR1B1.70083416
19BRAF1.64787445
20NME11.62908185
21BCKDK1.60872211
22BRSK21.57463869
23IRAK31.56418002
24ABL21.44648354
25CCNB11.41740517
26MAPKAPK31.40507032
27BMPR21.37909883
28TSSK61.35696861
29CASK1.31348741
30CDK81.31085918
31PDK21.30448082
32DYRK21.25401660
33BMPR1B1.23855663
34WNK31.20271487
35SRPK11.18847828
36TNIK1.16846274
37CDK191.15046813
38DYRK31.14169452
39MAP4K21.12477147
40IRAK41.10627698
41AURKA1.08456207
42PLK21.08173360
43MAP3K111.07709443
44GRK51.06509395
45EPHA21.01167834
46MUSK1.00290231
47ERBB40.97913938
48ZAK0.97279502
49ATR0.97170111
50TESK20.94263099
51MYLK0.92525878
52TEC0.91776867
53RPS6KB20.91562514
54BCR0.89784732
55SCYL20.88258547
56ZAP700.86288549
57PAK40.85139479
58PLK10.83906178
59PLK30.83750287
60GRK70.83424293
61MAP3K30.82992422
62KDR0.82021804
63CSNK1G10.81736484
64CSNK1G30.81735383
65MAP3K140.81042694
66TBK10.80842077
67MAP4K10.80510538
68TLK10.76779325
69TYK20.76467263
70NEK90.74090749
71PASK0.73845258
72TESK10.73161489
73RPS6KA40.72971280
74PRKCI0.71961945
75PBK0.70894491
76MAP2K30.70088740
77STK40.68463567
78CSNK2A10.67579613
79AURKB0.67344373
80CDK70.67278026
81STK240.66907352
82STK30.65852313
83RIPK40.65759214
84CSNK1G20.65526101
85IKBKB0.65041653
86OXSR10.64468707
87EIF2AK20.64443634
88SYK0.63380530
89PIM10.63188210
90TGFBR10.63069247
91LIMK10.62624741
92ATM0.62487857
93STK38L0.62424063
94CHEK10.62331950
95ERBB30.61107943
96KIT0.60439741
97STK390.60136907
98NLK0.59879712
99CSNK2A20.59186970
100BRSK10.58535131
101AKT30.56632455
102ALK0.56360157
103MKNK10.55586371
104ILK0.55419214
105PAK10.55028474
106CSNK1A1L0.54117381
107MAP3K50.53960725
108DAPK10.53824676
109TXK0.49968045
110MAP3K60.49204552
111GRK10.47298607
112NEK20.44490367
113ADRBK20.44490130
114RAF10.43733075
115MAP2K60.43363935
116DAPK30.41771807
117LYN0.41337192
118FGFR10.40812881
119STK100.40501202
120MAP3K80.39709553
121TTK0.38780285
122BTK0.37600656
123CDC70.37131882
124TIE10.36474041
125MAP2K20.36009056
126NEK10.34708066
127MOS0.34042045
128INSRR0.33567800
129YES10.33106235
130CHEK20.33020808
131CSNK1E0.32936543
132MKNK20.32918002
133PRKCD0.32480431
134RPS6KA50.32013665
135AKT20.30893317
136CDK10.26466650
137CDK20.25897871
138PRKCG0.25373372
139CDK90.24778894
140FLT30.22854390

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.12697810
2Ribosome_Homo sapiens_hsa030104.63591167
3RNA polymerase_Homo sapiens_hsa030204.02950547
4Protein export_Homo sapiens_hsa030603.20565352
5Oxidative phosphorylation_Homo sapiens_hsa001903.17028514
6DNA replication_Homo sapiens_hsa030302.78780516
7Pyrimidine metabolism_Homo sapiens_hsa002402.62767866
8Parkinsons disease_Homo sapiens_hsa050122.53893063
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.33259989
10Mismatch repair_Homo sapiens_hsa034302.19596357
11Homologous recombination_Homo sapiens_hsa034402.14000779
12Folate biosynthesis_Homo sapiens_hsa007902.12688318
13Huntingtons disease_Homo sapiens_hsa050162.00306194
14Nucleotide excision repair_Homo sapiens_hsa034201.89308035
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.83272643
16Vitamin B6 metabolism_Homo sapiens_hsa007501.73101937
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.71611231
18Alzheimers disease_Homo sapiens_hsa050101.70433779
19Spliceosome_Homo sapiens_hsa030401.70429083
20Base excision repair_Homo sapiens_hsa034101.69660650
21RNA transport_Homo sapiens_hsa030131.64523063
22Propanoate metabolism_Homo sapiens_hsa006401.62516769
23Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.61985623
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.49507370
25Basal transcription factors_Homo sapiens_hsa030221.40631801
26Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38247126
27Purine metabolism_Homo sapiens_hsa002301.33547179
28Non-homologous end-joining_Homo sapiens_hsa034501.32150807
29Other glycan degradation_Homo sapiens_hsa005111.31007925
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.27972408
31Regulation of autophagy_Homo sapiens_hsa041401.27361242
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.24125491
33Glutathione metabolism_Homo sapiens_hsa004801.12171114
34RNA degradation_Homo sapiens_hsa030181.09586271
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09264918
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.08638827
37Collecting duct acid secretion_Homo sapiens_hsa049661.06414871
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.05563537
39Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.05501549
40Epstein-Barr virus infection_Homo sapiens_hsa051691.03839579
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03581017
42Sulfur relay system_Homo sapiens_hsa041221.02244732
43Cell cycle_Homo sapiens_hsa041100.97211411
44Fanconi anemia pathway_Homo sapiens_hsa034600.96946060
45mRNA surveillance pathway_Homo sapiens_hsa030150.91937282
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87009969
47Lysosome_Homo sapiens_hsa041420.86026085
48Pentose phosphate pathway_Homo sapiens_hsa000300.85025204
49Vibrio cholerae infection_Homo sapiens_hsa051100.83398035
50Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82038235
51Arachidonic acid metabolism_Homo sapiens_hsa005900.81714020
52Legionellosis_Homo sapiens_hsa051340.81223560
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80514507
54p53 signaling pathway_Homo sapiens_hsa041150.78856258
55Metabolic pathways_Homo sapiens_hsa011000.75371505
56One carbon pool by folate_Homo sapiens_hsa006700.73428111
57Rheumatoid arthritis_Homo sapiens_hsa053230.71474202
58Fatty acid elongation_Homo sapiens_hsa000620.69347332
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67036857
60Oocyte meiosis_Homo sapiens_hsa041140.66971275
61Fructose and mannose metabolism_Homo sapiens_hsa000510.66283063
62Cysteine and methionine metabolism_Homo sapiens_hsa002700.66226163
63Sphingolipid metabolism_Homo sapiens_hsa006000.65307997
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64909861
65Butanoate metabolism_Homo sapiens_hsa006500.64692248
66Antigen processing and presentation_Homo sapiens_hsa046120.64265659
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62665006
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61786573
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.60413172
70Phagosome_Homo sapiens_hsa041450.59606730
71Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57925909
72Sulfur metabolism_Homo sapiens_hsa009200.56230621
73Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.55984465
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.53411306
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.52168379
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51529498
77Fatty acid metabolism_Homo sapiens_hsa012120.50114337
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48624322
79Caffeine metabolism_Homo sapiens_hsa002320.47836515
80Staphylococcus aureus infection_Homo sapiens_hsa051500.47606208
81N-Glycan biosynthesis_Homo sapiens_hsa005100.47401299
82Carbon metabolism_Homo sapiens_hsa012000.46886098
83Fatty acid degradation_Homo sapiens_hsa000710.45055321
84Linoleic acid metabolism_Homo sapiens_hsa005910.43699495
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.41182727
86Peroxisome_Homo sapiens_hsa041460.40680979
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40367686
88Steroid biosynthesis_Homo sapiens_hsa001000.40149370
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.39961596
90Shigellosis_Homo sapiens_hsa051310.39716171
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.39431733
92Selenocompound metabolism_Homo sapiens_hsa004500.38595782
93Tryptophan metabolism_Homo sapiens_hsa003800.38005175
94Pertussis_Homo sapiens_hsa051330.37236091
95Primary immunodeficiency_Homo sapiens_hsa053400.37110081
96Phototransduction_Homo sapiens_hsa047440.36868573
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36824244
98Histidine metabolism_Homo sapiens_hsa003400.36372321
99Galactose metabolism_Homo sapiens_hsa000520.35921254
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32916133
101Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.32378041
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30623421
103Cardiac muscle contraction_Homo sapiens_hsa042600.30304708
104Vitamin digestion and absorption_Homo sapiens_hsa049770.30049075
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28936433
106TGF-beta signaling pathway_Homo sapiens_hsa043500.28529809
107Biosynthesis of amino acids_Homo sapiens_hsa012300.28251094
108Hematopoietic cell lineage_Homo sapiens_hsa046400.28064808
109Retinol metabolism_Homo sapiens_hsa008300.26409003
110Phenylalanine metabolism_Homo sapiens_hsa003600.26029623
111Arginine and proline metabolism_Homo sapiens_hsa003300.25908337
112Nitrogen metabolism_Homo sapiens_hsa009100.24398238
113Apoptosis_Homo sapiens_hsa042100.24319287
114Pyruvate metabolism_Homo sapiens_hsa006200.24020060
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22932391
116Chemical carcinogenesis_Homo sapiens_hsa052040.21898389
117Systemic lupus erythematosus_Homo sapiens_hsa053220.21813997
118Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21709613
119beta-Alanine metabolism_Homo sapiens_hsa004100.21249400
120Herpes simplex infection_Homo sapiens_hsa051680.21115227
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.20521527
122Graft-versus-host disease_Homo sapiens_hsa053320.19286678
123Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.19231235
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.13357947
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.11968028
126Tyrosine metabolism_Homo sapiens_hsa003500.11954281
127Hippo signaling pathway_Homo sapiens_hsa043900.11501923
128Basal cell carcinoma_Homo sapiens_hsa052170.11074572
129Fat digestion and absorption_Homo sapiens_hsa049750.10094746
130Arginine biosynthesis_Homo sapiens_hsa002200.09475383
131Wnt signaling pathway_Homo sapiens_hsa043100.09077354
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.08896678

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