TRIM14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies and its function has not been determined. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.92082693
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.92082693
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.40573602
4antigen processing and presentation of endogenous antigen (GO:0019883)6.18091257
5negative regulation of cell killing (GO:0031342)4.77975519
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.77975519
7positive regulation of gamma-delta T cell activation (GO:0046645)4.59208003
8antigen processing and presentation via MHC class Ib (GO:0002475)4.32004536
9regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.13216319
10regulation of B cell receptor signaling pathway (GO:0050855)3.87594420
11response to type I interferon (GO:0034340)3.83371298
12cellular response to type I interferon (GO:0071357)3.83032740
13type I interferon signaling pathway (GO:0060337)3.83032740
14positive regulation by symbiont of host defense response (GO:0052509)3.77196502
15modulation by symbiont of host defense response (GO:0052031)3.77196502
16modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.77196502
17modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.77196502
18positive regulation by organism of defense response of other organism involved in symbiotic interact3.77196502
19modulation by symbiont of host immune response (GO:0052553)3.77196502
20regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.76115399
21regulation of dendritic cell antigen processing and presentation (GO:0002604)3.66391689
22positive thymic T cell selection (GO:0045059)3.64891409
23positive regulation of interferon-alpha production (GO:0032727)3.62403833
24interferon-gamma production (GO:0032609)3.50690861
25regulation of interferon-alpha production (GO:0032647)3.47010995
26T cell migration (GO:0072678)3.43774703
27negative regulation of T cell mediated immunity (GO:0002710)3.42003755
28positive regulation of humoral immune response (GO:0002922)3.40419197
29positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.39526158
30positive regulation of antigen processing and presentation (GO:0002579)3.38742384
31negative regulation of interleukin-12 production (GO:0032695)3.34773949
32thymic T cell selection (GO:0045061)3.31391876
33positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.30522869
34T cell selection (GO:0045058)3.29821452
35negative regulation of lymphocyte mediated immunity (GO:0002707)3.26271738
36positive regulation of B cell differentiation (GO:0045579)3.22330899
37regulation of gamma-delta T cell activation (GO:0046643)3.20771329
38B cell mediated immunity (GO:0019724)3.19930622
39positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.17000719
40tryptophan catabolic process (GO:0006569)3.16897665
41indole-containing compound catabolic process (GO:0042436)3.16897665
42indolalkylamine catabolic process (GO:0046218)3.16897665
43negative regulation of erythrocyte differentiation (GO:0045647)3.15475316
44immunoglobulin mediated immune response (GO:0016064)3.12793465
45detection of external biotic stimulus (GO:0098581)3.09969067
46regulation of gamma-delta T cell differentiation (GO:0045586)3.09862272
47positive T cell selection (GO:0043368)3.06831565
48regulation of T cell tolerance induction (GO:0002664)3.06426762
49response to interferon-alpha (GO:0035455)3.06083114
50complement activation, alternative pathway (GO:0006957)3.03210783
51regulation of interferon-beta biosynthetic process (GO:0045357)3.02100536
52negative T cell selection (GO:0043383)3.01876217
53tolerance induction (GO:0002507)3.00428749
54response to host immune response (GO:0052572)2.98992605
55response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.98992605
56response to interferon-beta (GO:0035456)2.97401061
57regulation of alpha-beta T cell proliferation (GO:0046640)2.97196418
58negative regulation of leukocyte mediated immunity (GO:0002704)2.96190136
59tryptophan metabolic process (GO:0006568)2.95674033
60leukocyte aggregation (GO:0070486)2.94884315
61cellular response to interferon-beta (GO:0035458)2.94369016
62interferon-gamma-mediated signaling pathway (GO:0060333)2.93457135
63positive regulation of granulocyte differentiation (GO:0030854)2.91120101
64aromatic amino acid family catabolic process (GO:0009074)2.90613108
65regulation of antigen processing and presentation (GO:0002577)2.90037908
66positive regulation of interferon-beta production (GO:0032728)2.88578361
67triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.87154057
68regulation of B cell differentiation (GO:0045577)2.86879620
69cellular response to interleukin-15 (GO:0071350)2.86420899
70defense response to protozoan (GO:0042832)2.86169460
71regulation of RIG-I signaling pathway (GO:0039535)2.85807518
72mature B cell differentiation (GO:0002335)2.85606044
73negative thymic T cell selection (GO:0045060)2.85174373
74regulation of tolerance induction (GO:0002643)2.84553606
75regulation of T cell mediated cytotoxicity (GO:0001914)2.83602201
76lipopolysaccharide-mediated signaling pathway (GO:0031663)2.83148500
77negative regulation of innate immune response (GO:0045824)2.79693143
78respiratory burst (GO:0045730)2.79440399
79JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.77088866
80protein carboxylation (GO:0018214)2.76486887
81peptidyl-glutamic acid carboxylation (GO:0017187)2.76486887
82regulation of T-helper 1 cell differentiation (GO:0045625)2.76062980
83myeloid cell activation involved in immune response (GO:0002275)2.75836190
84positive regulation of alpha-beta T cell proliferation (GO:0046641)2.74956247
85germinal center formation (GO:0002467)2.73589025
86response to interleukin-15 (GO:0070672)2.72992305
87myeloid dendritic cell activation (GO:0001773)2.72925566
88B cell receptor signaling pathway (GO:0050853)2.72896062
89CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.72304537
90T-helper cell differentiation (GO:0042093)2.72304537
91response to peptidoglycan (GO:0032494)2.71196041
92regulation of interleukin-12 biosynthetic process (GO:0045075)2.70943462
93fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.70126103
94response to host (GO:0075136)2.69362767
95response to host defenses (GO:0052200)2.69362767
96response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.69362767
97regulation of interleukin-2 biosynthetic process (GO:0045076)2.68659485
98cellular response to interferon-gamma (GO:0071346)2.68399988
99urea metabolic process (GO:0019627)2.68228860
100urea cycle (GO:0000050)2.68228860
101detection of biotic stimulus (GO:0009595)2.68216544
102NAD biosynthetic process (GO:0009435)2.68066747
103regulation of type I interferon-mediated signaling pathway (GO:0060338)2.67355433
104negative regulation of cytokine production involved in immune response (GO:0002719)2.67334646
105mature B cell differentiation involved in immune response (GO:0002313)2.67152209
106regulation of protein activation cascade (GO:2000257)2.66321317
107positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.65900741
108negative regulation of viral genome replication (GO:0045071)2.64499725
109NIK/NF-kappaB signaling (GO:0038061)2.64176168
110neutrophil activation involved in immune response (GO:0002283)2.63382125
111kynurenine metabolic process (GO:0070189)2.62696115
112positive regulation of immunoglobulin mediated immune response (GO:0002891)2.62398566
113positive regulation of B cell mediated immunity (GO:0002714)2.62398566
114cellular extravasation (GO:0045123)2.62040385
115response to protozoan (GO:0001562)2.61946155
116interferon-gamma secretion (GO:0072643)2.61664235
117detection of other organism (GO:0098543)2.60645167
118detection of bacterium (GO:0016045)2.59816380
119myeloid dendritic cell differentiation (GO:0043011)2.59813864
120mast cell activation (GO:0045576)2.59050308
121erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.58316434
122L-phenylalanine catabolic process (GO:0006559)2.58316434
123regulation of humoral immune response (GO:0002920)2.58242107
124response to muramyl dipeptide (GO:0032495)2.58142549
125regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.57074602
126lymph node development (GO:0048535)2.56888528
127positive regulation of type 2 immune response (GO:0002830)2.56470484
128regulation of natural killer cell mediated immunity (GO:0002715)2.56202095
129regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.56202095
130Peyers patch development (GO:0048541)2.55882086
131mucosal-associated lymphoid tissue development (GO:0048537)2.55882086
132positive regulation of T cell mediated cytotoxicity (GO:0001916)2.54653310
133cellular response to exogenous dsRNA (GO:0071360)2.54483161
134macrophage activation involved in immune response (GO:0002281)2.53443169
135negative regulation of myeloid cell apoptotic process (GO:0033033)2.53082784
136bile acid biosynthetic process (GO:0006699)2.52892285

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.89150170
2IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.78118747
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.63062577
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.39366846
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.33518024
6EGR1_23403033_ChIP-Seq_LIVER_Mouse4.14452257
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.07721328
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.70001074
9MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.08280858
10STAT4_19710469_ChIP-ChIP_TH1__Mouse3.01314021
11IRF8_27001747_Chip-Seq_BMDM_Mouse2.97297216
12* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.92003555
13* RXR_22158963_ChIP-Seq_LIVER_Mouse2.86586632
14SCL_19346495_ChIP-Seq_HPC-7_Human2.84505691
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.83378061
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.73968675
17* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.70686267
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.70362764
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.63353690
20GATA1_22025678_ChIP-Seq_K562_Human2.48638600
21RUNX_20019798_ChIP-Seq_JUKART_Human2.33226722
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.29129203
23MYB_21317192_ChIP-Seq_ERMYB_Mouse2.26360242
24CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.25409287
25FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.18532744
26* LXR_22158963_ChIP-Seq_LIVER_Mouse2.17587061
27MYB_26560356_Chip-Seq_TH2_Human2.10757773
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.08554065
29* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.99317514
30FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.97355331
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.93576869
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.92496152
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.87847211
34MYB_26560356_Chip-Seq_TH1_Human1.86947478
35NOTCH1_21737748_ChIP-Seq_TLL_Human1.84820726
36STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.83041396
37MAF_26560356_Chip-Seq_TH1_Human1.82845003
38SPI1_23547873_ChIP-Seq_NB4_Human1.82316242
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.80400529
40BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.79973394
41* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.71032679
42* LXR_22292898_ChIP-Seq_THP-1_Human1.70546358
43KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.70248134
44KDM2B_26808549_Chip-Seq_SUP-B15_Human1.67061804
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.64362727
46ELF1_17652178_ChIP-ChIP_JURKAT_Human1.63349718
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.61750531
48LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.59423712
49LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.58590325
50KDM2B_26808549_Chip-Seq_DND41_Human1.58285357
51* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.54136629
52ELK3_25401928_ChIP-Seq_HUVEC_Human1.54010573
53GATA2_22383799_ChIP-Seq_G1ME_Mouse1.53482910
54MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.52592778
55ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49335148
56PU_27001747_Chip-Seq_BMDM_Mouse1.48238440
57NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.46133457
58VDR_24763502_ChIP-Seq_THP-1_Human1.43660825
59* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.40313650
60PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.39640743
61TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38875016
62E2F7_22180533_ChIP-Seq_HELA_Human1.38296823
63UTX_26944678_Chip-Seq_JUKART_Human1.37926258
64E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35882448
65VDR_21846776_ChIP-Seq_THP-1_Human1.34749329
66BCL6_27268052_Chip-Seq_Bcells_Human1.32471777
67BCOR_27268052_Chip-Seq_Bcells_Human1.28863874
68GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.26452814
69VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.25220493
70EGR1_19374776_ChIP-ChIP_THP-1_Human1.24210394
71GATA3_27048872_Chip-Seq_THYMUS_Human1.24192316
72GATA1_19941826_ChIP-Seq_K562_Human1.23965506
73* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.21954599
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20930125
75TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.19953706
76CIITA_25753668_ChIP-Seq_RAJI_Human1.19380641
77NCOR1_26117541_ChIP-Seq_K562_Human1.18187101
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.16021189
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.15265015
80CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12331662
81RACK7_27058665_Chip-Seq_MCF-7_Human1.12235062
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.11322965
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10750125
84P68_20966046_ChIP-Seq_HELA_Human1.09967531
85GATA3_26560356_Chip-Seq_TH2_Human1.09544327
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.09242552
87GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07440800
88HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06896592
89SPI1_23127762_ChIP-Seq_K562_Human1.06476651
90TP63_17297297_ChIP-ChIP_HaCaT_Human1.04763745
91GATA1_19941827_ChIP-Seq_MEL_Mouse1.03374555
92VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01934482
93MAF_26560356_Chip-Seq_TH2_Human1.01319503
94* MYC_22102868_ChIP-Seq_BL_Human1.00022647
95SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98897919
96* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98056399
97NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.96940357
98KDM2B_26808549_Chip-Seq_JURKAT_Human0.96289848
99PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95646556
100TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94799106
101GATA2_21666600_ChIP-Seq_HMVEC_Human0.93557751
102CTCF_27219007_Chip-Seq_ERYTHROID_Human0.93131613
103* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92946167
104SA1_27219007_Chip-Seq_ERYTHROID_Human0.92840194
105SMC4_20622854_ChIP-Seq_HELA_Human0.92002577
106P300_27268052_Chip-Seq_Bcells_Human0.90317558
107GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89215636
108VDR_24787735_ChIP-Seq_THP-1_Human0.89015242
109GATA2_19941826_ChIP-Seq_K562_Human0.88233761
110TCF7_22412390_ChIP-Seq_EML_Mouse0.85113035
111TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.83966803
112FLI1_27457419_Chip-Seq_LIVER_Mouse0.81281235
113RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.80368458
114PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77684199
115PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.73069172
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.72298791
117NFE2_27457419_Chip-Seq_LIVER_Mouse0.71347863
118ETS1_22383799_ChIP-Seq_G1ME_Mouse0.69915650
119PU.1_20513432_ChIP-Seq_Bcells_Mouse0.67783309
120KAP1_22055183_ChIP-Seq_ESCs_Mouse0.67649599
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.66200214
122PCGF2_27294783_Chip-Seq_NPCs_Mouse0.66191760
123SUZ12_27294783_Chip-Seq_NPCs_Mouse0.65815143
124* RXRA_24833708_ChIP-Seq_LIVER_Mouse0.65691889
125NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.64860485
126SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.60996208
127THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.60936775

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.95101243
2MP0009785_altered_susceptibility_to3.31603619
3MP0002139_abnormal_hepatobiliary_system3.15395273
4MP0005671_abnormal_response_to3.10662901
5MP0005360_urolithiasis3.01555934
6MP0003436_decreased_susceptibility_to2.91201560
7MP0000685_abnormal_immune_system2.88852480
8MP0005387_immune_system_phenotype2.67025059
9MP0001790_abnormal_immune_system2.67025059
10MP0001800_abnormal_humoral_immune2.65790432
11MP0005025_abnormal_response_to2.61746802
12MP0005000_abnormal_immune_tolerance2.47015844
13MP0005085_abnormal_gallbladder_physiolo2.46609240
14MP0005365_abnormal_bile_salt2.42932210
15MP0002419_abnormal_innate_immunity2.36876658
16MP0002723_abnormal_immune_serum2.35793624
17MP0002148_abnormal_hypersensitivity_rea2.35071894
18MP0002452_abnormal_antigen_presenting2.32402431
19MP0003724_increased_susceptibility_to2.26331619
20MP0003763_abnormal_thymus_physiology2.25216958
21MP0006082_CNS_inflammation2.23063966
22MP0005464_abnormal_platelet_physiology2.18250380
23MP0001819_abnormal_immune_cell2.10318146
24MP0002420_abnormal_adaptive_immunity2.10150255
25MP0002166_altered_tumor_susceptibility1.93305371
26MP0008875_abnormal_xenobiotic_pharmacok1.88957951
27MP0009840_abnormal_foam_cell1.87366436
28MP0001853_heart_inflammation1.79445392
29MP0010155_abnormal_intestine_physiology1.78696744
30MP0002398_abnormal_bone_marrow1.78365606
31MP0002006_tumorigenesis1.77025986
32MP0008469_abnormal_protein_level1.77010237
33MP0004381_abnormal_hair_follicle1.74806158
34MP0001845_abnormal_inflammatory_respons1.74791780
35MP0000716_abnormal_immune_system1.74115897
36MP0002138_abnormal_hepatobiliary_system1.72012699
37MP0009764_decreased_sensitivity_to1.70930837
38MP0004510_myositis1.63885172
39MP0000689_abnormal_spleen_morphology1.62185889
40MP0004947_skin_inflammation1.61854278
41MP0003252_abnormal_bile_duct1.59509184
42MP0002405_respiratory_system_inflammati1.57643065
43MP0005174_abnormal_tail_pigmentation1.51964895
44MP0002722_abnormal_immune_system1.48705809
45MP0010329_abnormal_lipoprotein_level1.47516673
46MP0005075_abnormal_melanosome_morpholog1.44570605
47MP0001873_stomach_inflammation1.43740363
48MP0002429_abnormal_blood_cell1.42298906
49MP0002396_abnormal_hematopoietic_system1.41811355
50MP0003191_abnormal_cellular_cholesterol1.40860979
51MP0009278_abnormal_bone_marrow1.40198076
52MP0009763_increased_sensitivity_to1.39992371
53MP0003806_abnormal_nucleotide_metabolis1.39212047
54MP0000609_abnormal_liver_physiology1.38417204
55MP0005310_abnormal_salivary_gland1.38376221
56MP0009333_abnormal_splenocyte_physiolog1.34218677
57MP0002009_preneoplasia1.31191759
58MP0003866_abnormal_defecation1.31026765
59MP0003300_gastrointestinal_ulcer1.30801977
60MP0003303_peritoneal_inflammation1.27957752
61MP0005058_abnormal_lysosome_morphology1.27344178
62MP0001533_abnormal_skeleton_physiology1.26649494
63MP0005083_abnormal_biliary_tract1.15600835
64MP0001545_abnormal_hematopoietic_system1.15523517
65MP0005397_hematopoietic_system_phenotyp1.15523517
66MP0001666_abnormal_nutrient_absorption1.14340718
67MP0001764_abnormal_homeostasis1.11624412
68MP0003868_abnormal_feces_composition1.07698552
69MP0000015_abnormal_ear_pigmentation1.06922281
70MP0000703_abnormal_thymus_morphology1.05791998
71MP0001663_abnormal_digestive_system1.05460134
72MP0009765_abnormal_xenobiotic_induced1.04403848
73MP0000490_abnormal_crypts_of1.03345664
74MP0002132_abnormal_respiratory_system1.02469476
75MP0003075_altered_response_to1.02067998
76MP0005319_abnormal_enzyme/_coenzyme1.01099533
77MP0004808_abnormal_hematopoietic_stem1.00929749
78MP0005451_abnormal_body_composition1.00496062
79MP0000465_gastrointestinal_hemorrhage0.99023812
80MP0003045_fibrosis0.98692312
81MP0004019_abnormal_vitamin_homeostasis0.97191730
82MP0003172_abnormal_lysosome_physiology0.95586697
83MP0009697_abnormal_copulation0.94420678
84MP0005076_abnormal_cell_differentiation0.94001482
85MP0003195_calcinosis0.93594297
86MP0003186_abnormal_redox_activity0.92962600
87MP0002933_joint_inflammation0.91803146
88MP0004264_abnormal_extraembryonic_tissu0.91658533
89MP0002998_abnormal_bone_remodeling0.89569513
90MP0001851_eye_inflammation0.89413533
91MP0000858_altered_metastatic_potential0.89150095
92MP0005332_abnormal_amino_acid0.87969633
93MP0003656_abnormal_erythrocyte_physiolo0.87704614
94MP0005584_abnormal_enzyme/coenzyme_acti0.87165577
95MP0000598_abnormal_liver_morphology0.86428981
96MP0002118_abnormal_lipid_homeostasis0.85858621
97MP0003448_altered_tumor_morphology0.85380431
98MP0008260_abnormal_autophagy0.83742438
99MP0003453_abnormal_keratinocyte_physiol0.79900857
100MP0004883_abnormal_blood_vessel0.78703838
101MP0001986_abnormal_taste_sensitivity0.75744400
102MP0005647_abnormal_sex_gland0.75334392
103MP0003183_abnormal_peptide_metabolism0.74168662
104MP0002928_abnormal_bile_duct0.73130438
105MP0005166_decreased_susceptibility_to0.72922184
106MP0005164_abnormal_response_to0.71633992
107MP0009643_abnormal_urine_homeostasis0.71433752
108MP0002136_abnormal_kidney_physiology0.69542713
109MP0010234_abnormal_vibrissa_follicle0.69093926
110MP0009642_abnormal_blood_homeostasis0.69062178
111MP0000604_amyloidosis0.67245507
112MP0002095_abnormal_skin_pigmentation0.66515000
113MP0004858_abnormal_nervous_system0.66164710
114MP0002019_abnormal_tumor_incidence0.66055750
115MP0000477_abnormal_intestine_morphology0.65025002
116MP0000371_diluted_coat_color0.64960314
117MP0005381_digestive/alimentary_phenotyp0.62085411
118MP0000249_abnormal_blood_vessel0.61922858
119MP0005390_skeleton_phenotype0.61688541
120MP0010307_abnormal_tumor_latency0.58751261

Predicted human phenotypes

RankGene SetZ-score
1Chronic otitis media (HP:0000389)4.29319168
2Recurrent gram-negative bacterial infections (HP:0005420)4.27318830
3Joint hemorrhage (HP:0005261)4.22046607
4Recurrent abscess formation (HP:0002722)4.04892782
5Elevated erythrocyte sedimentation rate (HP:0003565)4.02657758
6Myositis (HP:0100614)4.02382075
7Eczematoid dermatitis (HP:0000976)3.96599436
8Prolonged partial thromboplastin time (HP:0003645)3.93356322
9Recurrent bacterial skin infections (HP:0005406)3.92279102
10Retrobulbar optic neuritis (HP:0100654)3.69743505
11Optic neuritis (HP:0100653)3.69743505
12Orchitis (HP:0100796)3.65949698
13Gingival bleeding (HP:0000225)3.48067780
14Recurrent fungal infections (HP:0002841)3.42333419
15Increased IgE level (HP:0003212)3.36736790
16Recurrent viral infections (HP:0004429)3.23522159
17Recurrent skin infections (HP:0001581)3.23428096
18Complement deficiency (HP:0004431)3.19801146
19Autoimmune thrombocytopenia (HP:0001973)3.16126502
20Vasculitis (HP:0002633)3.13911047
21Nasal polyposis (HP:0100582)3.13204676
22Recurrent bronchitis (HP:0002837)3.11987063
23Meningitis (HP:0001287)3.10331438
24Recurrent cutaneous fungal infections (HP:0011370)3.08456230
25Chronic mucocutaneous candidiasis (HP:0002728)3.08456230
26Systemic lupus erythematosus (HP:0002725)3.07117538
27Intrahepatic cholestasis (HP:0001406)3.06994006
28Abnormal delayed hypersensitivity skin test (HP:0002963)3.04576420
29Stomatitis (HP:0010280)2.96287808
30Epistaxis (HP:0000421)2.93195782
31Mediastinal lymphadenopathy (HP:0100721)2.92022575
32Gastrointestinal stroma tumor (HP:0100723)2.87265535
33Abnormality of macrophages (HP:0004311)2.81403390
34Abnormality of monocarboxylic acid metabolism (HP:0010996)2.80889722
35Prolonged bleeding time (HP:0003010)2.80087108
36Autoimmune hemolytic anemia (HP:0001890)2.79600350
37IgM deficiency (HP:0002850)2.79584894
38Deep venous thrombosis (HP:0002625)2.78324812
39Encephalitis (HP:0002383)2.73834724
40Abnormality of T cell number (HP:0011839)2.73260035
41Abnormality of aromatic amino acid family metabolism (HP:0004338)2.71849886
42Agammaglobulinemia (HP:0004432)2.70910737
43Keratoconjunctivitis sicca (HP:0001097)2.69960713
44Inflammation of the large intestine (HP:0002037)2.68479083
45T lymphocytopenia (HP:0005403)2.68190887
46Vacuolated lymphocytes (HP:0001922)2.67634753
47Abnormality of the fingertips (HP:0001211)2.63234687
48Menorrhagia (HP:0000132)2.62929529
49Arterial thrombosis (HP:0004420)2.62716200
50Abnormality of the nasal mucosa (HP:0000433)2.62133515
51Abnormality of the common coagulation pathway (HP:0010990)2.61241928
52Abnormality of T cells (HP:0002843)2.59501521
53Pustule (HP:0200039)2.57897001
54Malnutrition (HP:0004395)2.56722182
55Pulmonary embolism (HP:0002204)2.56339533
56Granulocytopenia (HP:0001913)2.54977740
57Panhypogammaglobulinemia (HP:0003139)2.54479357
58Xanthomatosis (HP:0000991)2.54313923
59Hyperlipoproteinemia (HP:0010980)2.51762787
60Gastrointestinal inflammation (HP:0004386)2.49736236
61Abnormality of the prostate (HP:0008775)2.49046049
62Abnormality of complement system (HP:0005339)2.46894809
63Abnormality of T cell physiology (HP:0011840)2.46796425
64Abnormality of pyrimidine metabolism (HP:0004353)2.46203984
65Gingivitis (HP:0000230)2.45979080
66Keratoconjunctivitis (HP:0001096)2.45368866
67Colitis (HP:0002583)2.44624211
68Chronic diarrhea (HP:0002028)2.43667519
69Periodontitis (HP:0000704)2.43456078
70Chronic sinusitis (HP:0011109)2.43426496
71Spontaneous hematomas (HP:0007420)2.42296977
72Myocardial infarction (HP:0001658)2.40626779
73Cellulitis (HP:0100658)2.40273217
74Increased cerebral lipofuscin (HP:0011813)2.39970388
75Hypobetalipoproteinemia (HP:0003563)2.39014490
76Abnormality of B cell number (HP:0010975)2.38877671
77Recurrent sinusitis (HP:0011108)2.38604179
78Glomerulonephritis (HP:0000099)2.38513366
79Chronic obstructive pulmonary disease (HP:0006510)2.37020045
80Obstructive lung disease (HP:0006536)2.37020045
81Joint swelling (HP:0001386)2.36608829
82Reduced antithrombin III activity (HP:0001976)2.36521426
83Chest pain (HP:0100749)2.35930520
84Thrombophlebitis (HP:0004418)2.34273964
85Hypergammaglobulinemia (HP:0010702)2.34238012
86Severe combined immunodeficiency (HP:0004430)2.33497208
87Pulmonary infiltrates (HP:0002113)2.32010801
88Hemoptysis (HP:0002105)2.29163491
89Increased neuronal autofluorescent lipopigment (HP:0002074)2.28375240
90Conjugated hyperbilirubinemia (HP:0002908)2.24994756
91Emphysema (HP:0002097)2.24310341
92Osteomyelitis (HP:0002754)2.23914435
93Dysostosis multiplex (HP:0000943)2.23745437
94Increased serum ferritin (HP:0003281)2.22614032
95Increased IgM level (HP:0003496)2.22227785
96Verrucae (HP:0200043)2.19679602
97Papilloma (HP:0012740)2.19679602
98IgG deficiency (HP:0004315)2.19400354
99Hypertensive crisis (HP:0100735)2.19019535
100Petechiae (HP:0000967)2.16248530
101Skin rash (HP:0000988)2.16054477
102Thrombocytosis (HP:0001894)2.14787577
103Abnormality of the pleura (HP:0002103)2.14136178
104Gastrointestinal infarctions (HP:0005244)2.11497727
105Microcytic anemia (HP:0001935)2.10867802
106Abnormal platelet function (HP:0011869)2.10671435
107Impaired platelet aggregation (HP:0003540)2.10671435
108Hemorrhage of the eye (HP:0011885)2.10575950
109Gangrene (HP:0100758)2.10090264
110Hypoplasia of the thymus (HP:0000778)2.09921137
111B lymphocytopenia (HP:0010976)2.09719493
112Anorexia (HP:0002039)2.08705196
113Lymphopenia (HP:0001888)2.05567936
114Skin ulcer (HP:0200042)2.05514252
115Hypochromic anemia (HP:0001931)2.05348209
116Cheilitis (HP:0100825)2.04904036
117Urticaria (HP:0001025)2.04600703
118Thyroid-stimulating hormone excess (HP:0002925)2.03859780
119Vascular calcification (HP:0004934)2.02458158
120Abnormality of cells of the lymphoid lineage (HP:0012140)2.02455842
121Purpura (HP:0000979)2.02222946
122Fat malabsorption (HP:0002630)2.01175715
123Abnormality of liposaccharide metabolism (HP:0010968)2.00984954
124Abnormality of glycosphingolipid metabolism (HP:0004343)2.00984954
125Abnormality of glycolipid metabolism (HP:0010969)2.00984954
126Basal ganglia calcification (HP:0002135)2.00887971
127Abnormality of iron homeostasis (HP:0011031)2.00364377
128Combined immunodeficiency (HP:0005387)1.99488561
129Leukocytosis (HP:0001974)1.99343272
130Eosinophilia (HP:0001880)1.99253423
131Epidermoid cyst (HP:0200040)1.98142892
132Loss of speech (HP:0002371)1.96690596
133Sepsis (HP:0100806)1.94722286
134Fatigue (HP:0012378)1.91182284
135Abnormality of glycosaminoglycan metabolism (HP:0004371)1.90874595

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.97066767
2TXK3.41931959
3TYK23.23070073
4MAP3K143.20076760
5IKBKE3.01814464
6PRPF4B2.88393852
7IRAK32.87417207
8IRAK42.79630581
9JAK32.66459129
10FGFR42.48431023
11TBK12.40055459
12BLK2.38732465
13KIT2.35634793
14TAOK32.30220474
15JAK12.12367500
16IKBKB1.94370743
17BTK1.86161510
18TEC1.84918614
19ZAP701.83457372
20ERN11.81013669
21SMG11.70485255
22TRIB31.65374474
23NME21.64620288
24SYK1.53133155
25TLK11.47356544
26CDK121.47302372
27STK161.45600707
28ITK1.44413790
29MAP3K101.42008522
30ZAK1.39572576
31RIPK41.38378461
32PIM11.37499599
33MAP3K131.35324336
34TGFBR21.34846822
35CSF1R1.33749006
36LCK1.29264826
37HCK1.26338298
38TESK21.26024452
39FLT31.23626064
40GRK61.18021270
41LYN1.17674676
42TAOK11.15486875
43NLK1.15348357
44FGFR31.14914069
45CHUK1.14470493
46CSK1.13603132
47EEF2K1.12189027
48STK101.08916259
49IRAK11.08479814
50MAP2K31.06645999
51EIF2AK21.05202556
52MKNK21.03224052
53MAP3K11.02647091
54JAK21.01476989
55EPHA31.00796964
56STK41.00417875
57BCKDK0.97142005
58HIPK20.96886193
59TAOK20.96700182
60FES0.94125949
61CDC42BPA0.93477370
62MAP3K20.92689574
63RIPK10.92666478
64PIM20.91714912
65INSRR0.90025142
66YES10.89666295
67SIK10.84698729
68SCYL20.84192066
69MST40.79826073
70PRKD20.78800410
71MAPK110.78781194
72SIK30.78558234
73EPHB10.78028997
74PRKCQ0.77900943
75MST1R0.76124898
76CDK40.75581585
77FGR0.73487797
78KDR0.71930476
79TNK20.71177441
80GRK70.68399377
81MAP3K120.67450181
82PDPK10.64781357
83ICK0.62109193
84NEK90.61657567
85LRRK20.61600055
86PIK3CG0.61457845
87MATK0.61200987
88MAPK40.60793313
89RPS6KL10.59808425
90RPS6KC10.59808425
91ADRBK20.58239598
92BMPR20.56564654
93KSR20.56523411
94CAMK1D0.55588135
95CDK60.54740468
96TNIK0.54020071
97RPS6KA60.53674338
98MAPKAPK30.52883759
99MAP2K20.52849795
100CLK10.52786312
101CAMKK20.50955181
102MAPKAPK20.49855199
103RPS6KA50.49402067
104SIK20.48177656
105PTK60.47219763
106NUAK10.46146176
107RPS6KA40.43551220
108MELK0.43361546
109IRAK20.41895384
110MAP3K80.41748423
111PRKCD0.40058528
112ABL10.39884149
113MARK30.39857752
114CAMKK10.38663111
115MAP2K60.38602605
116STK240.38265513
117MARK20.37279413
118WNK40.37088282
119EIF2AK30.35783805
120PRKAA20.35442197
121MAPK70.35288862
122CDK90.34397860
123TRPM70.33779586
124PBK0.33083226
125MAP3K110.32430947
126EGFR0.31384507
127BMPR1B0.29931111
128VRK10.29767734
129PKN10.29707494
130GRK10.28787458
131IGF1R0.28417783
132PDK10.27692531
133SGK20.27031409
134MAP3K30.24009196
135ACVR1B0.23494270

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.04565126
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.92384589
3Primary immunodeficiency_Homo sapiens_hsa053402.74154010
4Complement and coagulation cascades_Homo sapiens_hsa046102.43870248
5Caffeine metabolism_Homo sapiens_hsa002322.39384256
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.25286124
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.21604258
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.17947501
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.13629566
10Measles_Homo sapiens_hsa051622.12059692
11Allograft rejection_Homo sapiens_hsa053302.03348727
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.01112281
13Leishmaniasis_Homo sapiens_hsa051401.94296887
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.90313007
15Systemic lupus erythematosus_Homo sapiens_hsa053221.82842317
16Graft-versus-host disease_Homo sapiens_hsa053321.82370557
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.75124806
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.74659021
19ABC transporters_Homo sapiens_hsa020101.64994931
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.62409935
21Osteoclast differentiation_Homo sapiens_hsa043801.49641791
22Peroxisome_Homo sapiens_hsa041461.42307299
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.42164999
24Herpes simplex infection_Homo sapiens_hsa051681.40942409
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.39988791
26Tryptophan metabolism_Homo sapiens_hsa003801.38938434
27B cell receptor signaling pathway_Homo sapiens_hsa046621.38200588
28Antigen processing and presentation_Homo sapiens_hsa046121.36947029
29Hematopoietic cell lineage_Homo sapiens_hsa046401.33132392
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.32612369
31Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.31850139
32Influenza A_Homo sapiens_hsa051641.30017759
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.29394387
34Fatty acid degradation_Homo sapiens_hsa000711.28633330
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.28022927
36Chemical carcinogenesis_Homo sapiens_hsa052041.24717702
37Histidine metabolism_Homo sapiens_hsa003401.24377207
38Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.23638676
39Cyanoamino acid metabolism_Homo sapiens_hsa004601.22745983
40Arginine biosynthesis_Homo sapiens_hsa002201.21652994
41Steroid hormone biosynthesis_Homo sapiens_hsa001401.20468542
42Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.16127747
43Other glycan degradation_Homo sapiens_hsa005111.13636233
44Autoimmune thyroid disease_Homo sapiens_hsa053201.13381969
45Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.12528101
46Pertussis_Homo sapiens_hsa051331.08621036
47Malaria_Homo sapiens_hsa051441.08081558
48Retinol metabolism_Homo sapiens_hsa008301.07781334
49T cell receptor signaling pathway_Homo sapiens_hsa046601.07756315
50Legionellosis_Homo sapiens_hsa051341.07338727
51Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.04324998
52TNF signaling pathway_Homo sapiens_hsa046681.04114340
53Nitrogen metabolism_Homo sapiens_hsa009101.02885679
54beta-Alanine metabolism_Homo sapiens_hsa004101.00421995
55Asthma_Homo sapiens_hsa053100.99168481
56PPAR signaling pathway_Homo sapiens_hsa033200.98783820
57Hepatitis C_Homo sapiens_hsa051600.93678997
58Toxoplasmosis_Homo sapiens_hsa051450.91651205
59Tuberculosis_Homo sapiens_hsa051520.90732936
60Vitamin digestion and absorption_Homo sapiens_hsa049770.87724839
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85743859
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.85383129
63Non-small cell lung cancer_Homo sapiens_hsa052230.83882632
64Chronic myeloid leukemia_Homo sapiens_hsa052200.83293732
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81685131
66Epstein-Barr virus infection_Homo sapiens_hsa051690.81653172
67Selenocompound metabolism_Homo sapiens_hsa004500.80621485
68Starch and sucrose metabolism_Homo sapiens_hsa005000.80179636
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79730189
70Pancreatic cancer_Homo sapiens_hsa052120.77859008
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.76259133
72Leukocyte transendothelial migration_Homo sapiens_hsa046700.75106292
73Apoptosis_Homo sapiens_hsa042100.74066510
74Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.74041961
75One carbon pool by folate_Homo sapiens_hsa006700.73104335
76Phagosome_Homo sapiens_hsa041450.70467996
77Hepatitis B_Homo sapiens_hsa051610.68937342
78Fructose and mannose metabolism_Homo sapiens_hsa000510.68922783
79Renin-angiotensin system_Homo sapiens_hsa046140.68877418
80Type I diabetes mellitus_Homo sapiens_hsa049400.68841206
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67677368
82African trypanosomiasis_Homo sapiens_hsa051430.67188230
83VEGF signaling pathway_Homo sapiens_hsa043700.67046744
84Pentose phosphate pathway_Homo sapiens_hsa000300.66899363
85Folate biosynthesis_Homo sapiens_hsa007900.64993357
86Lysine degradation_Homo sapiens_hsa003100.64953381
87Platelet activation_Homo sapiens_hsa046110.63955144
88Chemokine signaling pathway_Homo sapiens_hsa040620.62881789
89Phenylalanine metabolism_Homo sapiens_hsa003600.61272884
90HTLV-I infection_Homo sapiens_hsa051660.61173381
91Fatty acid metabolism_Homo sapiens_hsa012120.59902936
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59423674
93Insulin resistance_Homo sapiens_hsa049310.58131486
94Salmonella infection_Homo sapiens_hsa051320.57857116
95Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56878686
96Acute myeloid leukemia_Homo sapiens_hsa052210.53712740
97Sulfur relay system_Homo sapiens_hsa041220.51398841
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49306931
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48721431
100Rheumatoid arthritis_Homo sapiens_hsa053230.47848067
101Tyrosine metabolism_Homo sapiens_hsa003500.47705121
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.47628940
103Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46748866
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.46702884
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46279966
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.45601543
107Arachidonic acid metabolism_Homo sapiens_hsa005900.45149155
108Lysosome_Homo sapiens_hsa041420.42205088
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41813367
110Viral carcinogenesis_Homo sapiens_hsa052030.41101334
111Fatty acid elongation_Homo sapiens_hsa000620.40199769
112Prolactin signaling pathway_Homo sapiens_hsa049170.38239167
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.37737909
114Fat digestion and absorption_Homo sapiens_hsa049750.37685504
115Shigellosis_Homo sapiens_hsa051310.37176374
116Renal cell carcinoma_Homo sapiens_hsa052110.35411152
117Viral myocarditis_Homo sapiens_hsa054160.35184540
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.35056754
119Bladder cancer_Homo sapiens_hsa052190.34703087
120SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33942276
121p53 signaling pathway_Homo sapiens_hsa041150.32947109
122Bile secretion_Homo sapiens_hsa049760.32550252
123Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.32187586
124Notch signaling pathway_Homo sapiens_hsa043300.31019131
125Steroid biosynthesis_Homo sapiens_hsa001000.30932106
126Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30809900
127Galactose metabolism_Homo sapiens_hsa000520.30698446
128Linoleic acid metabolism_Homo sapiens_hsa005910.30513133
129Endocytosis_Homo sapiens_hsa041440.30169347
130mTOR signaling pathway_Homo sapiens_hsa041500.30055172
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.29118257
132Choline metabolism in cancer_Homo sapiens_hsa052310.27009939
133Prostate cancer_Homo sapiens_hsa052150.24702293
134alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.24684254
135FoxO signaling pathway_Homo sapiens_hsa040680.24568113
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23238881
137Inositol phosphate metabolism_Homo sapiens_hsa005620.22869365
138Thyroid cancer_Homo sapiens_hsa052160.21947393
139Endometrial cancer_Homo sapiens_hsa052130.21371574
140Prion diseases_Homo sapiens_hsa050200.21290623
141Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21290130

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