Rank | Gene Set | Z-score |
---|---|---|
1 | epithelial cilium movement (GO:0003351) | 9.92210114 |
2 | motile cilium assembly (GO:0044458) | 9.72791526 |
3 | reproduction (GO:0000003) | 9.69591114 |
4 | spermatid development (GO:0007286) | 9.63798458 |
5 | axonemal dynein complex assembly (GO:0070286) | 9.50189901 |
6 | cilium or flagellum-dependent cell motility (GO:0001539) | 8.95068512 |
7 | regulation of cilium movement (GO:0003352) | 8.43971822 |
8 | cilium movement (GO:0003341) | 8.03754796 |
9 | single fertilization (GO:0007338) | 7.49067469 |
10 | sperm capacitation (GO:0048240) | 7.48342706 |
11 | response to pheromone (GO:0019236) | 7.46516268 |
12 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 7.37034553 |
13 | protein targeting to Golgi (GO:0000042) | 7.36560652 |
14 | microtubule depolymerization (GO:0007019) | 7.25187727 |
15 | piRNA metabolic process (GO:0034587) | 7.22431638 |
16 | negative regulation of inclusion body assembly (GO:0090084) | 7.21379832 |
17 | establishment of protein localization to Golgi (GO:0072600) | 7.05702019 |
18 | male meiosis (GO:0007140) | 6.94861126 |
19 | synaptonemal complex organization (GO:0070193) | 6.91046620 |
20 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 6.88808830 |
21 | rRNA methylation (GO:0031167) | 6.84409846 |
22 | spermatogenesis (GO:0007283) | 6.80636781 |
23 | male gamete generation (GO:0048232) | 6.77955237 |
24 | synaptonemal complex assembly (GO:0007130) | 6.69360580 |
25 | centriole replication (GO:0007099) | 6.65141560 |
26 | organic cation transport (GO:0015695) | 6.59826968 |
27 | fertilization (GO:0009566) | 6.26124302 |
28 | gamete generation (GO:0007276) | 6.22460616 |
29 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 5.92186740 |
30 | regulation of inclusion body assembly (GO:0090083) | 5.91600797 |
31 | calcium ion-dependent exocytosis (GO:0017156) | 5.76609314 |
32 | rRNA modification (GO:0000154) | 5.70689943 |
33 | spermatid nucleus differentiation (GO:0007289) | 5.56829643 |
34 | phosphatidylethanolamine metabolic process (GO:0046337) | 5.45968575 |
35 | germ cell development (GO:0007281) | 5.37761580 |
36 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 5.33433146 |
37 | glycerol ether metabolic process (GO:0006662) | 5.26862041 |
38 | protein localization to Golgi apparatus (GO:0034067) | 5.23117994 |
39 | ventricular system development (GO:0021591) | 5.10702609 |
40 | regulation of centriole replication (GO:0046599) | 5.08978778 |
41 | regulation of microtubule-based movement (GO:0060632) | 5.07392109 |
42 | cell recognition (GO:0008037) | 5.04818374 |
43 | chromosome condensation (GO:0030261) | 4.98083886 |
44 | multicellular organismal reproductive process (GO:0048609) | 4.88387304 |
45 | ether metabolic process (GO:0018904) | 4.86348354 |
46 | male meiosis I (GO:0007141) | 4.76620024 |
47 | positive regulation of Rab GTPase activity (GO:0032851) | 4.75150152 |
48 | regulation of Rab GTPase activity (GO:0032313) | 4.75150152 |
49 | DNA packaging (GO:0006323) | 4.70627922 |
50 | DNA methylation involved in gamete generation (GO:0043046) | 4.70277657 |
51 | cellular ketone body metabolic process (GO:0046950) | 4.56618322 |
52 | chromosome organization involved in meiosis (GO:0070192) | 4.52259339 |
53 | microtubule severing (GO:0051013) | 4.40915741 |
54 | meiotic nuclear division (GO:0007126) | 4.33408505 |
55 | sexual reproduction (GO:0019953) | 4.29128894 |
56 | left/right pattern formation (GO:0060972) | 4.26458294 |
57 | single strand break repair (GO:0000012) | 4.24804900 |
58 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.15791472 |
59 | ketone body metabolic process (GO:1902224) | 4.01276262 |
60 | multicellular organismal development (GO:0007275) | 4.00631674 |
61 | glomerular visceral epithelial cell development (GO:0072015) | 4.00425722 |
62 | seminiferous tubule development (GO:0072520) | 3.99618193 |
63 | histone H3-K9 demethylation (GO:0033169) | 3.98638637 |
64 | chaperone-mediated protein complex assembly (GO:0051131) | 3.95072111 |
65 | microtubule polymerization or depolymerization (GO:0031109) | 3.94571437 |
66 | microtubule nucleation (GO:0007020) | 3.93116303 |
67 | regulation of transcription involved in cell fate commitment (GO:0060850) | 3.85991928 |
68 | glomerular epithelial cell development (GO:0072310) | 3.77885519 |
69 | meiosis I (GO:0007127) | 3.74527058 |
70 | sequestering of actin monomers (GO:0042989) | 3.73891681 |
71 | multicellular organismal movement (GO:0050879) | 3.72796508 |
72 | musculoskeletal movement (GO:0050881) | 3.72796508 |
73 | protein polyglutamylation (GO:0018095) | 3.52136004 |
74 | regulation of meiosis I (GO:0060631) | 3.51837850 |
75 | cellular response to pH (GO:0071467) | 3.50514254 |
76 | response to acidic pH (GO:0010447) | 3.48113195 |
77 | nuclear pore complex assembly (GO:0051292) | 3.40455108 |
78 | protein refolding (GO:0042026) | 3.37950805 |
79 | negative regulation of Rho protein signal transduction (GO:0035024) | 3.35997406 |
80 | meiotic cell cycle (GO:0051321) | 3.34421184 |
81 | cerebral cortex neuron differentiation (GO:0021895) | 3.32080505 |
82 | negative regulation of histone methylation (GO:0031061) | 3.30410401 |
83 | protein K11-linked deubiquitination (GO:0035871) | 3.28161783 |
84 | regulation of spindle checkpoint (GO:0090231) | 3.20278491 |
85 | genitalia morphogenesis (GO:0035112) | 3.15733238 |
86 | protein localization to cilium (GO:0061512) | 3.14566631 |
87 | coenzyme catabolic process (GO:0009109) | 3.13531961 |
88 | membrane protein intracellular domain proteolysis (GO:0031293) | 3.10526848 |
89 | nucleus organization (GO:0006997) | 3.06948618 |
90 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.04905223 |
91 | regulation of histone H3-K9 methylation (GO:0051570) | 3.04209618 |
92 | regulation of interleukin-13 production (GO:0032656) | 3.04063057 |
93 | DNA conformation change (GO:0071103) | 3.00423474 |
94 | amino-acid betaine transport (GO:0015838) | 3.00365599 |
95 | carnitine transport (GO:0015879) | 3.00365599 |
96 | peptidyl-threonine dephosphorylation (GO:0035970) | 2.97576530 |
97 | regulation of female gonad development (GO:2000194) | 2.97355896 |
98 | protein-DNA complex disassembly (GO:0032986) | 2.96173818 |
99 | nucleosome disassembly (GO:0006337) | 2.96173818 |
100 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.93459656 |
101 | homeostasis of number of cells within a tissue (GO:0048873) | 2.93080928 |
102 | glycolytic process (GO:0006096) | 2.91384702 |
103 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.90514458 |
104 | GTP biosynthetic process (GO:0006183) | 2.89282248 |
105 | centrosome duplication (GO:0051298) | 2.85472722 |
106 | polyamine biosynthetic process (GO:0006596) | 2.83658522 |
107 | interferon-gamma secretion (GO:0072643) | 2.82329074 |
108 | carnitine transmembrane transport (GO:1902603) | 2.81629468 |
109 | alditol metabolic process (GO:0019400) | 2.79230312 |
110 | meiotic cell cycle process (GO:1903046) | 2.78063422 |
111 | axoneme assembly (GO:0035082) | 2.77420862 |
112 | cilium organization (GO:0044782) | 2.74365502 |
113 | RNA localization (GO:0006403) | 2.73520699 |
114 | positive regulation of macrophage activation (GO:0043032) | 2.73411604 |
115 | polyol catabolic process (GO:0046174) | 2.72769275 |
116 | centriole assembly (GO:0098534) | 2.68441507 |
117 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.66766279 |
118 | cilium assembly (GO:0042384) | 2.66003381 |
119 | mitotic sister chromatid cohesion (GO:0007064) | 2.62674861 |
120 | synapsis (GO:0007129) | 2.61798551 |
121 | microtubule-based movement (GO:0007018) | 2.61343183 |
122 | protein depolymerization (GO:0051261) | 2.60982321 |
123 | RNA destabilization (GO:0050779) | 2.60040533 |
124 | cellular component assembly involved in morphogenesis (GO:0010927) | 2.58672875 |
125 | regulation of cilium assembly (GO:1902017) | 2.57113671 |
126 | chromatin silencing (GO:0006342) | 2.54417907 |
127 | UTP biosynthetic process (GO:0006228) | 2.53836222 |
128 | peptidyl-glutamic acid modification (GO:0018200) | 2.50923857 |
129 | cilium morphogenesis (GO:0060271) | 2.49111592 |
130 | intraciliary transport (GO:0042073) | 2.40994206 |
131 | gene silencing by RNA (GO:0031047) | 2.39577264 |
132 | negative regulation of skeletal muscle tissue development (GO:0048642) | 2.37838922 |
133 | sperm motility (GO:0030317) | 14.3749733 |
134 | cell wall macromolecule catabolic process (GO:0016998) | 13.6149489 |
135 | cell wall macromolecule metabolic process (GO:0044036) | 13.6149489 |
136 | fusion of sperm to egg plasma membrane (GO:0007342) | 13.4742255 |
137 | acrosome reaction (GO:0007340) | 12.3064907 |
138 | sperm-egg recognition (GO:0035036) | 11.5616764 |
139 | multicellular organism reproduction (GO:0032504) | 11.2400889 |
140 | acrosome assembly (GO:0001675) | 10.7435941 |
141 | cell-cell recognition (GO:0009988) | 10.3368141 |
142 | plasma membrane fusion (GO:0045026) | 10.2729980 |
143 | binding of sperm to zona pellucida (GO:0007339) | 10.2226271 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 8.71266538 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.69787885 |
3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.63350085 |
4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.02062325 |
5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.45148759 |
6 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 3.18615102 |
7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.10381885 |
8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.85751880 |
9 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.63269611 |
10 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.61695666 |
11 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.56720481 |
12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.35950971 |
13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.18317982 |
14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.17845793 |
15 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 2.07449449 |
16 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 2.05454220 |
17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.97066097 |
18 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.96300729 |
19 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.95671112 |
20 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.94768818 |
21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.93757023 |
22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.90051005 |
23 | ERA_21632823_ChIP-Seq_H3396_Human | 1.85360755 |
24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.85151205 |
25 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.79773796 |
26 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.77582556 |
27 | * FUS_26573619_Chip-Seq_HEK293_Human | 1.77216848 |
28 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.77161549 |
29 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.76588049 |
30 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.76241988 |
31 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.73107896 |
32 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.71874578 |
33 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.70532982 |
34 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.69219481 |
35 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.66678322 |
36 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.61468131 |
37 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.60720813 |
38 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.60353610 |
39 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.58814270 |
40 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.58758373 |
41 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.58688188 |
42 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.57923785 |
43 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.57321383 |
44 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.57209227 |
45 | AR_25329375_ChIP-Seq_VCAP_Human | 1.56911669 |
46 | * FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55625698 |
47 | KDM2B_26808549_Chip-Seq_REH_Human | 1.54100914 |
48 | * GATA3_21867929_ChIP-Seq_CD8_Mouse | 1.52863513 |
49 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.50598615 |
50 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.50054967 |
51 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.48158494 |
52 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.47223998 |
53 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.46797835 |
54 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.46465107 |
55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.46028952 |
56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.46028952 |
57 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.44952390 |
58 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.44513014 |
59 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.43965149 |
60 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.42565309 |
61 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.40844760 |
62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39635018 |
63 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.39212539 |
64 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.39142836 |
65 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.39015034 |
66 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.38057877 |
67 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 1.37619724 |
68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.37301641 |
69 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.37097920 |
70 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.36834579 |
71 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.36369369 |
72 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.35621357 |
73 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.35111686 |
74 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.33882353 |
75 | P68_20966046_ChIP-Seq_HELA_Human | 1.33766532 |
76 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.33321031 |
77 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.33241746 |
78 | * CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.32532973 |
79 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.32293666 |
80 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.31825947 |
81 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.31673833 |
82 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.31583619 |
83 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.31533601 |
84 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.31134647 |
85 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.30949552 |
86 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.30304118 |
87 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.27661957 |
88 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.26760272 |
89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.26688107 |
90 | CEBPB_22108803_ChIP-Seq_LS180_Human | 1.24516862 |
91 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.23795349 |
92 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.23330923 |
93 | P300_27268052_Chip-Seq_Bcells_Human | 1.23178610 |
94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.22837687 |
95 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22774979 |
96 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.22724118 |
97 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.21013151 |
98 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 1.20520427 |
99 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.20343135 |
100 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.20309426 |
101 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.20175046 |
102 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.19402723 |
103 | GF1_26923725_Chip-Seq_HPCs_Mouse | 1.18893301 |
104 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.18451957 |
105 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.17585229 |
106 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.17145971 |
107 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.16749582 |
108 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.16654564 |
109 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.15156212 |
110 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.14679917 |
111 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14229429 |
112 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.13921417 |
113 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.13875131 |
114 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12675826 |
115 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 1.12605900 |
116 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.12234443 |
117 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.11922932 |
118 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.11487277 |
119 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.10958230 |
120 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10640463 |
121 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.10537683 |
122 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 1.10485480 |
123 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.10110279 |
124 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.08953613 |
125 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.07683040 |
126 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.07638567 |
127 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.07584802 |
128 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07584802 |
129 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.07454836 |
130 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.07432857 |
131 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.06852776 |
132 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06303196 |
133 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06303196 |
134 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05803735 |
135 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.05800622 |
136 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.05078843 |
137 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.05043969 |
138 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.04967357 |
139 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.04375196 |
140 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.04333300 |
141 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.04246218 |
142 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.04066867 |
143 | NFYB_21822215_ChIP-Seq_K562_Human | 1.04066731 |
144 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.03724602 |
145 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.03573712 |
146 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 1.02941939 |
147 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.02630384 |
148 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.02477417 |
149 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02140876 |
150 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.02118380 |
151 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.02091761 |
152 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01516450 |
153 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.01458083 |
154 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.01069149 |
155 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.00197101 |
156 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00130486 |
157 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.99848162 |
158 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.99349422 |
159 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98570542 |
160 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.98272718 |
161 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.97803950 |
162 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.96187412 |
163 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.96084591 |
164 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.94577471 |
165 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.94424618 |
166 | TBL1_22424771_ChIP-Seq_293T_Human | 0.93607283 |
167 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.93525410 |
168 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.93225786 |
169 | * JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.92748613 |
170 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.92079854 |
171 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.89647544 |
172 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.89228632 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003698_abnormal_male_reproductive | 6.04167749 |
2 | MP0001929_abnormal_gametogenesis | 5.48871018 |
3 | MP0008877_abnormal_DNA_methylation | 3.86529025 |
4 | MP0003718_maternal_effect | 3.64190148 |
5 | MP0002210_abnormal_sex_determination | 3.40137841 |
6 | MP0001348_abnormal_lacrimal_gland | 3.32043936 |
7 | MP0002161_abnormal_fertility/fecundity | 3.26780474 |
8 | MP0001145_abnormal_male_reproductive | 2.90412282 |
9 | MP0005670_abnormal_white_adipose | 2.82289479 |
10 | MP0000653_abnormal_sex_gland | 2.50496265 |
11 | MP0000678_abnormal_parathyroid_gland | 2.44524519 |
12 | MP0002653_abnormal_ependyma_morphology | 2.16123814 |
13 | MP0005410_abnormal_fertilization | 16.2101928 |
14 | MP0003646_muscle_fatigue | 1.97855895 |
15 | MP0005379_endocrine/exocrine_gland_phen | 1.80909558 |
16 | MP0002138_abnormal_hepatobiliary_system | 1.73212222 |
17 | MP0002132_abnormal_respiratory_system | 1.69234412 |
18 | MP0005623_abnormal_meninges_morphology | 1.60388310 |
19 | MP0001486_abnormal_startle_reflex | 1.52344049 |
20 | MP0005395_other_phenotype | 1.51434223 |
21 | MP0003329_amyloid_beta_deposits | 1.49874261 |
22 | MP0005310_abnormal_salivary_gland | 1.48848171 |
23 | MP0002282_abnormal_trachea_morphology | 1.48775173 |
24 | MP0001485_abnormal_pinna_reflex | 1.48413548 |
25 | MP0004233_abnormal_muscle_weight | 1.34896160 |
26 | MP0002160_abnormal_reproductive_system | 1.32357399 |
27 | MP0002249_abnormal_larynx_morphology | 1.31704971 |
28 | MP0005647_abnormal_sex_gland | 1.18204896 |
29 | MP0002234_abnormal_pharynx_morphology | 1.15268267 |
30 | MP0001963_abnormal_hearing_physiology | 1.13404007 |
31 | MP0001765_abnormal_ion_homeostasis | 1.09000936 |
32 | MP0001984_abnormal_olfaction | 1.05832371 |
33 | MP0002127_abnormal_cardiovascular_syste | 1.03892368 |
34 | MP0002735_abnormal_chemical_nociception | 1.03284488 |
35 | MP0006292_abnormal_olfactory_placode | 1.02286371 |
36 | MP0008789_abnormal_olfactory_epithelium | 1.01196157 |
37 | MP0003878_abnormal_ear_physiology | 1.00253781 |
38 | MP0005377_hearing/vestibular/ear_phenot | 1.00253781 |
39 | MP0004859_abnormal_synaptic_plasticity | 0.97080644 |
40 | MP0009053_abnormal_anal_canal | 0.94888468 |
41 | MP0003077_abnormal_cell_cycle | 0.94244211 |
42 | MP0000026_abnormal_inner_ear | 0.89577622 |
43 | MP0002102_abnormal_ear_morphology | 0.88580937 |
44 | MP0009046_muscle_twitch | 0.87519418 |
45 | MP0004510_myositis | 0.82456418 |
46 | MP0005394_taste/olfaction_phenotype | 0.81344785 |
47 | MP0005499_abnormal_olfactory_system | 0.81344785 |
48 | MP0002229_neurodegeneration | 0.80703567 |
49 | MP0002139_abnormal_hepatobiliary_system | 0.79113960 |
50 | MP0000604_amyloidosis | 0.77700815 |
51 | MP0005248_abnormal_Harderian_gland | 0.76377206 |
52 | MP0008058_abnormal_DNA_repair | 0.73956829 |
53 | MP0008995_early_reproductive_senescence | 0.73721369 |
54 | MP0009697_abnormal_copulation | 0.72345179 |
55 | MP0002067_abnormal_sensory_capabilities | 0.72244422 |
56 | MP0005666_abnormal_adipose_tissue | 0.67767351 |
57 | MP0001666_abnormal_nutrient_absorption | 0.67713589 |
58 | MP0001986_abnormal_taste_sensitivity | 0.67662235 |
59 | MP0003011_delayed_dark_adaptation | 0.65978226 |
60 | MP0003115_abnormal_respiratory_system | 0.64360928 |
61 | MP0000955_abnormal_spinal_cord | 0.63345015 |
62 | MP0000049_abnormal_middle_ear | 0.63009183 |
63 | MP0005389_reproductive_system_phenotype | 0.61742529 |
64 | MP0005636_abnormal_mineral_homeostasis | 0.61384188 |
65 | MP0000681_abnormal_thyroid_gland | 0.60441002 |
66 | MP0008875_abnormal_xenobiotic_pharmacok | 0.59217623 |
67 | MP0002272_abnormal_nervous_system | 0.58886218 |
68 | MP0004085_abnormal_heartbeat | 0.58347138 |
69 | MP0001764_abnormal_homeostasis | 0.57770463 |
70 | MP0002733_abnormal_thermal_nociception | 0.57257002 |
71 | MP0003119_abnormal_digestive_system | 0.57125971 |
72 | MP0003252_abnormal_bile_duct | 0.56579754 |
73 | MP0005375_adipose_tissue_phenotype | 0.56456710 |
74 | MP0002557_abnormal_social/conspecific_i | 0.56364088 |
75 | MP0005167_abnormal_blood-brain_barrier | 0.52119184 |
76 | MP0000685_abnormal_immune_system | 0.51528332 |
77 | MP0002909_abnormal_adrenal_gland | 0.50253722 |
78 | MP0002736_abnormal_nociception_after | 0.50175501 |
79 | MP0008569_lethality_at_weaning | 0.49085837 |
80 | MP0003879_abnormal_hair_cell | 0.47649682 |
81 | MP0001879_abnormal_lymphatic_vessel | 0.45353525 |
82 | MP0001905_abnormal_dopamine_level | 0.45234483 |
83 | MP0000751_myopathy | 0.45022662 |
84 | MP0005253_abnormal_eye_physiology | 0.44838712 |
85 | MP0005083_abnormal_biliary_tract | 0.43288745 |
86 | MP0000003_abnormal_adipose_tissue | 0.42676179 |
87 | MP0003693_abnormal_embryo_hatching | 0.42449898 |
88 | MP0005551_abnormal_eye_electrophysiolog | 0.42348750 |
89 | MP0000534_abnormal_ureter_morphology | 0.41647985 |
90 | MP0000566_synostosis | 0.40941301 |
91 | MP0010307_abnormal_tumor_latency | 0.40918306 |
92 | MP0009250_abnormal_appendicular_skeleto | 0.40562374 |
93 | MP0005423_abnormal_somatic_nervous | 0.39926778 |
94 | MP0002734_abnormal_mechanical_nocicepti | 0.39831973 |
95 | MP0009745_abnormal_behavioral_response | 0.39465679 |
96 | MP0000358_abnormal_cell_content/ | 0.38047091 |
97 | MP0003942_abnormal_urinary_system | 0.38016146 |
98 | MP0005408_hypopigmentation | 0.37743478 |
99 | MP0001835_abnormal_antigen_presentation | 0.37698410 |
100 | MP0003699_abnormal_female_reproductive | 0.37437384 |
101 | MP0002405_respiratory_system_inflammati | 0.37267917 |
102 | MP0002269_muscular_atrophy | 0.36870869 |
103 | MP0003950_abnormal_plasma_membrane | 0.36822785 |
104 | MP0004036_abnormal_muscle_relaxation | 0.36313497 |
105 | MP0000470_abnormal_stomach_morphology | 0.36258222 |
106 | MP0000230_abnormal_systemic_arterial | 0.36059472 |
107 | MP0003866_abnormal_defecation | 0.35755426 |
108 | MP0002928_abnormal_bile_duct | 0.35218512 |
109 | MP0003633_abnormal_nervous_system | 0.34874790 |
110 | MP0001968_abnormal_touch/_nociception | 0.34471891 |
111 | MP0001501_abnormal_sleep_pattern | 0.34455269 |
112 | MP0004742_abnormal_vestibular_system | 0.34184598 |
113 | MP0001970_abnormal_pain_threshold | 0.34103432 |
114 | MP0001324_abnormal_eye_pigmentation | 0.32525216 |
115 | MP0000516_abnormal_urinary_system | 0.31738564 |
116 | MP0005367_renal/urinary_system_phenotyp | 0.31738564 |
117 | MP0003137_abnormal_impulse_conducting | 0.31185893 |
118 | MP0003045_fibrosis | 0.31112310 |
119 | MP0006072_abnormal_retinal_apoptosis | 0.31093761 |
120 | MP0000015_abnormal_ear_pigmentation | 0.31085560 |
121 | MP0001119_abnormal_female_reproductive | 0.30320255 |
122 | MP0005645_abnormal_hypothalamus_physiol | 0.29633036 |
123 | MP0010094_abnormal_chromosome_stability | 0.29239821 |
124 | MP0006082_CNS_inflammation | 0.28972753 |
125 | MP0002971_abnormal_brown_adipose | 0.28266397 |
126 | MP0001293_anophthalmia | 0.26783380 |
127 | MP0003111_abnormal_nucleus_morphology | 0.26005862 |
128 | MP0004019_abnormal_vitamin_homeostasis | 0.25296586 |
129 | MP0003959_abnormal_lean_body | 0.24982623 |
130 | MP0009115_abnormal_fat_cell | 0.24904338 |
131 | MP0010352_gastrointestinal_tract_polyps | 0.24688976 |
132 | MP0005535_abnormal_body_temperature | 0.24631331 |
133 | MP0006036_abnormal_mitochondrial_physio | 0.24545667 |
134 | MP0001545_abnormal_hematopoietic_system | 0.24149392 |
135 | MP0005397_hematopoietic_system_phenotyp | 0.24149392 |
136 | MP0004133_heterotaxia | 0.24014055 |
137 | MP0005391_vision/eye_phenotype | 0.22902057 |
138 | MP0003861_abnormal_nervous_system | 0.22546213 |
139 | MP0001440_abnormal_grooming_behavior | 0.22132480 |
140 | MP0000569_abnormal_digit_pigmentation | 0.21996056 |
141 | MP0003631_nervous_system_phenotype | 0.21404305 |
142 | MP0002169_no_abnormal_phenotype | 0.21374223 |
143 | MP0009278_abnormal_bone_marrow | 0.21366097 |
144 | MP0002873_normal_phenotype | 0.21063385 |
145 | MP0005503_abnormal_tendon_morphology | 0.20547293 |
146 | MP0004811_abnormal_neuron_physiology | 0.19565299 |
147 | MP0002152_abnormal_brain_morphology | 0.19501582 |
148 | MP0002572_abnormal_emotion/affect_behav | 0.18658099 |
149 | MP0003936_abnormal_reproductive_system | 0.18445488 |
150 | MP0003632_abnormal_nervous_system | 0.18266617 |
151 | MP0005451_abnormal_body_composition | 0.17087603 |
152 | MP0002693_abnormal_pancreas_physiology | 0.16938411 |
153 | MP0002108_abnormal_muscle_morphology | 0.16613711 |
154 | MP0002822_catalepsy | 0.15609169 |
155 | MP0009780_abnormal_chondrocyte_physiolo | 0.15349094 |
156 | MP0003786_premature_aging | 0.15339833 |
157 | MP0002295_abnormal_pulmonary_circulatio | 0.15126160 |
158 | MP0002109_abnormal_limb_morphology | 0.15097488 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal respiratory epithelium morphology (HP:0012253) | 9.14511422 |
2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 9.14511422 |
3 | Abnormal respiratory motile cilium physiology (HP:0012261) | 9.07792643 |
4 | Severe visual impairment (HP:0001141) | 7.57787230 |
5 | Abnormal ciliary motility (HP:0012262) | 7.29959808 |
6 | Rhinitis (HP:0012384) | 7.20666667 |
7 | Chronic bronchitis (HP:0004469) | 6.79218613 |
8 | Infertility (HP:0000789) | 6.64408812 |
9 | Nasal polyposis (HP:0100582) | 6.63150461 |
10 | Chronic hepatic failure (HP:0100626) | 5.43223607 |
11 | Abnormality of the nasal mucosa (HP:0000433) | 5.40382258 |
12 | Attenuation of retinal blood vessels (HP:0007843) | 4.70669603 |
13 | Bronchitis (HP:0012387) | 4.68310359 |
14 | Male infertility (HP:0003251) | 4.66758264 |
15 | Bony spicule pigmentary retinopathy (HP:0007737) | 4.63622625 |
16 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 4.55818639 |
17 | Bronchiectasis (HP:0002110) | 4.51621018 |
18 | Hyperkalemia (HP:0002153) | 4.47781084 |
19 | Resting tremor (HP:0002322) | 4.36249060 |
20 | Cone-rod dystrophy (HP:0000548) | 4.29577570 |
21 | Abnormality of macular pigmentation (HP:0008002) | 3.95707542 |
22 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 3.85996985 |
23 | Abnormal spermatogenesis (HP:0008669) | 3.83492488 |
24 | Nephronophthisis (HP:0000090) | 3.72946564 |
25 | Progressive sensorineural hearing impairment (HP:0000408) | 3.39498918 |
26 | Facial shape deformation (HP:0011334) | 3.39463808 |
27 | Potter facies (HP:0002009) | 3.39463808 |
28 | Truncal obesity (HP:0001956) | 3.36605483 |
29 | Recurrent otitis media (HP:0000403) | 3.35557256 |
30 | Recurrent sinusitis (HP:0011108) | 3.34994075 |
31 | Hypoalphalipoproteinemia (HP:0003233) | 3.33486655 |
32 | Hypoplasia of the thymus (HP:0000778) | 3.28455689 |
33 | Recurrent bronchitis (HP:0002837) | 3.27704856 |
34 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.26035490 |
35 | Menstrual irregularities (HP:0000858) | 3.23373374 |
36 | Enlarged epiphyses (HP:0010580) | 3.20633751 |
37 | Osteomalacia (HP:0002749) | 3.15034409 |
38 | Postural instability (HP:0002172) | 2.95498863 |
39 | Hypoplastic ischia (HP:0003175) | 2.92573435 |
40 | Abnormality of dental color (HP:0011073) | 2.87017645 |
41 | Progressive cerebellar ataxia (HP:0002073) | 2.86538759 |
42 | Amelogenesis imperfecta (HP:0000705) | 2.86346633 |
43 | Abnormality of the renal medulla (HP:0100957) | 2.81480038 |
44 | Portal hypertension (HP:0001409) | 2.81407635 |
45 | Generalized aminoaciduria (HP:0002909) | 2.81221987 |
46 | Renovascular hypertension (HP:0100817) | 2.80353300 |
47 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.71333872 |
48 | Impulsivity (HP:0100710) | 2.68753151 |
49 | Abnormality of the ischium (HP:0003174) | 2.59428809 |
50 | Abnormality of the hepatic vasculature (HP:0006707) | 2.56946562 |
51 | Tubulointerstitial nephritis (HP:0001970) | 2.52366712 |
52 | Hypophosphatemic rickets (HP:0004912) | 2.50066153 |
53 | Abnormality of potassium homeostasis (HP:0011042) | 2.46449956 |
54 | Abnormal urine output (HP:0012590) | 2.45946067 |
55 | Medial flaring of the eyebrow (HP:0010747) | 2.44080890 |
56 | Azoospermia (HP:0000027) | 2.42546453 |
57 | Unilateral renal agenesis (HP:0000122) | 2.40553594 |
58 | Horizontal nystagmus (HP:0000666) | 2.38542572 |
59 | Cholecystitis (HP:0001082) | 2.38534448 |
60 | Abnormal gallbladder physiology (HP:0012438) | 2.38534448 |
61 | Abnormality of the costochondral junction (HP:0000919) | 2.35355975 |
62 | Tubular atrophy (HP:0000092) | 2.29232322 |
63 | Gonadotropin excess (HP:0000837) | 2.25563882 |
64 | Intellectual disability, moderate (HP:0002342) | 2.25340953 |
65 | Subcapsular cataract (HP:0000523) | 2.21941385 |
66 | Increased purine levels (HP:0004368) | 2.21397257 |
67 | Hyperuricemia (HP:0002149) | 2.21397257 |
68 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.18824477 |
69 | Myokymia (HP:0002411) | 2.17494649 |
70 | Progressive hearing impairment (HP:0001730) | 2.16210513 |
71 | Abnormality of midbrain morphology (HP:0002418) | 2.15333351 |
72 | Molar tooth sign on MRI (HP:0002419) | 2.15333351 |
73 | Abnormality of the aortic arch (HP:0012303) | 2.09754821 |
74 | Tubulointerstitial abnormality (HP:0001969) | 2.07678876 |
75 | Dyschromatopsia (HP:0007641) | 2.06538681 |
76 | Optic nerve hypoplasia (HP:0000609) | 2.03823378 |
77 | Focal segmental glomerulosclerosis (HP:0000097) | 2.03197785 |
78 | Heterotopia (HP:0002282) | 2.02765914 |
79 | Absent/shortened dynein arms (HP:0200106) | 13.2772883 |
80 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 13.2772883 |
81 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 12.4250137 |
82 | Ventricular tachycardia (HP:0004756) | 1.98938925 |
83 | Polyuria (HP:0000103) | 1.96866526 |
84 | Congenital sensorineural hearing impairment (HP:0008527) | 1.91749510 |
85 | Hyponatremia (HP:0002902) | 1.90510654 |
86 | Abdominal situs inversus (HP:0003363) | 1.88030191 |
87 | Abnormality of abdominal situs (HP:0011620) | 1.88030191 |
88 | Short femoral neck (HP:0100864) | 1.87651692 |
89 | Abnormality of the parathyroid morphology (HP:0011766) | 1.86243172 |
90 | Spastic tetraparesis (HP:0001285) | 1.85614385 |
91 | Choroideremia (HP:0001139) | 1.83370385 |
92 | Congenital malformation of the right heart (HP:0011723) | 1.83348286 |
93 | Double outlet right ventricle (HP:0001719) | 1.83348286 |
94 | Recurrent pneumonia (HP:0006532) | 1.82617468 |
95 | Fibular hypoplasia (HP:0003038) | 1.82482944 |
96 | Decreased central vision (HP:0007663) | 1.81420416 |
97 | Photophobia (HP:0000613) | 1.79911694 |
98 | Type 2 muscle fiber atrophy (HP:0003554) | 1.79621543 |
99 | Widely patent fontanelles and sutures (HP:0004492) | 1.77556160 |
100 | Chronic sinusitis (HP:0011109) | 1.76062068 |
101 | Stomatitis (HP:0010280) | 1.75933444 |
102 | Anterior segment dysgenesis (HP:0007700) | 1.75919222 |
103 | Metaphyseal cupping (HP:0003021) | 1.75481399 |
104 | Sandal gap (HP:0001852) | 1.73054350 |
105 | Bile duct proliferation (HP:0001408) | 1.72561319 |
106 | Abnormal biliary tract physiology (HP:0012439) | 1.72561319 |
107 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.69230774 |
108 | Increased IgM level (HP:0003496) | 1.67367911 |
109 | Renal Fanconi syndrome (HP:0001994) | 1.65637288 |
110 | Short ribs (HP:0000773) | 1.65570917 |
111 | Epiphyseal dysplasia (HP:0002656) | 1.65263976 |
112 | Abnormality of the neuromuscular junction (HP:0003398) | 1.65075354 |
113 | Fatigable weakness (HP:0003473) | 1.65075354 |
114 | Asymmetric septal hypertrophy (HP:0001670) | 1.61114797 |
115 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.60501301 |
116 | Tubulointerstitial fibrosis (HP:0005576) | 1.60182364 |
117 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.60088734 |
118 | Absent epiphyses (HP:0010577) | 1.60088734 |
119 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.59812470 |
120 | Stage 5 chronic kidney disease (HP:0003774) | 1.59595253 |
121 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.59588797 |
122 | Glomerulosclerosis (HP:0000096) | 1.58789537 |
123 | Hypoalbuminemia (HP:0003073) | 1.58669423 |
124 | Abnormal albumin level (HP:0012116) | 1.58669423 |
125 | Postaxial foot polydactyly (HP:0001830) | 1.57602574 |
126 | Easy fatigability (HP:0003388) | 1.56539677 |
127 | Sensory axonal neuropathy (HP:0003390) | 1.52673980 |
128 | Neurofibrillary tangles (HP:0002185) | 1.51790114 |
129 | Metaphyseal dysplasia (HP:0100255) | 1.48229260 |
130 | Supernumerary spleens (HP:0009799) | 1.48133255 |
131 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.47305967 |
132 | Renal dysplasia (HP:0000110) | 1.45882307 |
133 | Muscle fiber atrophy (HP:0100295) | 1.45564685 |
134 | Gait imbalance (HP:0002141) | 1.43916225 |
135 | Abnormality of the renal cortex (HP:0011035) | 1.42987608 |
136 | Congenital primary aphakia (HP:0007707) | 1.42023568 |
137 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.41763101 |
138 | Hemorrhage of the eye (HP:0011885) | 1.41759682 |
139 | Bundle branch block (HP:0011710) | 1.41543085 |
140 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.40325621 |
141 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.40166094 |
142 | Abnormality of femoral epiphyses (HP:0006499) | 1.40166094 |
143 | Polydipsia (HP:0001959) | 1.39139315 |
144 | Abnormal drinking behavior (HP:0030082) | 1.39139315 |
145 | Short thorax (HP:0010306) | 1.38692102 |
146 | Short tibia (HP:0005736) | 1.38581573 |
147 | Bell-shaped thorax (HP:0001591) | 1.36871017 |
148 | Abnormality of renal excretion (HP:0011036) | 1.36799884 |
149 | Congenital hepatic fibrosis (HP:0002612) | 1.35239851 |
150 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.33949094 |
151 | Postaxial hand polydactyly (HP:0001162) | 1.33480374 |
152 | Irregular vertebral endplates (HP:0003301) | 1.33316277 |
153 | Abnormality of the femoral head (HP:0003368) | 1.26275181 |
154 | Mild short stature (HP:0003502) | 1.25935756 |
155 | Amyotrophic lateral sclerosis (HP:0007354) | 1.25135359 |
156 | Flattened epiphyses (HP:0003071) | 1.24986725 |
157 | Cerebellar dysplasia (HP:0007033) | 1.24216133 |
158 | Loss of speech (HP:0002371) | 1.23757861 |
159 | Oculomotor apraxia (HP:0000657) | 1.21671177 |
160 | Weak cry (HP:0001612) | 1.20126505 |
161 | Hypercholesterolemia (HP:0003124) | 1.19237405 |
162 | Abnormality of permanent molar morphology (HP:0011071) | 1.18738243 |
163 | Abnormality of the dental root (HP:0006486) | 1.18738243 |
164 | Taurodontia (HP:0000679) | 1.18738243 |
165 | Nephrogenic diabetes insipidus (HP:0009806) | 1.18055437 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PDK3 | 7.83187829 |
2 | PDK4 | 7.83187829 |
3 | TESK1 | 6.85020233 |
4 | PDK2 | 5.26899431 |
5 | PRKD3 | 5.26701391 |
6 | ICK | 4.24858313 |
7 | INSRR | 4.12116622 |
8 | BRD4 | 3.66605071 |
9 | PLK2 | 3.47579249 |
10 | MAP4K2 | 2.84412206 |
11 | WNK4 | 2.67824200 |
12 | STK39 | 2.26291327 |
13 | PTK2B | 1.74548341 |
14 | STK38 | 1.68327185 |
15 | DYRK1B | 1.66996579 |
16 | TESK2 | 1.66476001 |
17 | PNCK | 1.59656352 |
18 | MST1R | 1.46408774 |
19 | CDK7 | 1.40315549 |
20 | MET | 1.39895600 |
21 | NEK2 | 1.31225202 |
22 | KSR2 | 1.22777934 |
23 | PDK1 | 1.13014044 |
24 | MAP3K13 | 0.98642688 |
25 | WNK1 | 0.83707667 |
26 | CAMK1D | 0.77789407 |
27 | DYRK3 | 0.75281167 |
28 | AKT3 | 0.73886525 |
29 | IRAK1 | 0.72862445 |
30 | MAP3K12 | 0.66927513 |
31 | RIPK4 | 0.66332648 |
32 | PDPK1 | 0.65394644 |
33 | TTK | 0.64335562 |
34 | TIE1 | 0.64033239 |
35 | MAPK15 | 0.62276781 |
36 | LMTK2 | 0.58776398 |
37 | CAMK1 | 0.58721822 |
38 | PASK | 0.58609976 |
39 | LATS2 | 0.56443378 |
40 | SIK2 | 0.56148925 |
41 | PBK | 0.55604168 |
42 | TYRO3 | 0.55304002 |
43 | LATS1 | 0.54969473 |
44 | PRKAA2 | 0.53304451 |
45 | MAP2K6 | 0.53119425 |
46 | CHEK2 | 0.51969492 |
47 | MAP3K8 | 0.50913544 |
48 | CDK2 | 0.50108695 |
49 | MAP2K2 | 0.49465702 |
50 | STK38L | 0.49323098 |
51 | MUSK | 0.48844520 |
52 | ROCK1 | 0.46079918 |
53 | CDK1 | 0.44844814 |
54 | STK3 | 0.43057585 |
55 | PIK3CG | 0.41810859 |
56 | MAP3K2 | 0.40901192 |
57 | OXSR1 | 0.40812729 |
58 | MAPK1 | 0.40513236 |
59 | BRSK1 | 0.40397812 |
60 | RPS6KA2 | 0.40361907 |
61 | NTRK3 | 0.39329265 |
62 | CDK3 | 0.37783098 |
63 | BRAF | 0.37000579 |
64 | BMPR1B | 0.36904818 |
65 | UHMK1 | 0.36725495 |
66 | MOS | 0.36604414 |
67 | PRKCG | 0.36004557 |
68 | AURKA | 0.35501827 |
69 | CCNB1 | 0.34841366 |
70 | NTRK2 | 0.34734874 |
71 | PAK1 | 0.34689767 |
72 | CAMK1G | 0.33839499 |
73 | EIF2AK1 | 0.33300776 |
74 | SGK494 | 0.32002142 |
75 | SGK223 | 0.32002142 |
76 | IRAK2 | 0.31626390 |
77 | SGK1 | 0.30729801 |
78 | CDK19 | 0.30567106 |
79 | PLK4 | 0.30077876 |
80 | EEF2K | 0.28625824 |
81 | CDK9 | 0.27395476 |
82 | PRKG2 | 0.27168512 |
83 | MAP3K10 | 0.27091611 |
84 | CAMKK1 | 0.26767307 |
85 | CAMK4 | 0.26310717 |
86 | PAK4 | 0.25878182 |
87 | CSF1R | 0.25760494 |
88 | MAP3K4 | 0.25653412 |
89 | PINK1 | 0.25422016 |
90 | CHEK1 | 0.25021942 |
91 | ZAP70 | 0.24908874 |
92 | CDK4 | 0.24429924 |
93 | PRKCQ | 0.23771262 |
94 | MAP4K1 | 0.23255512 |
95 | TXK | 0.22703542 |
96 | LIMK1 | 0.22349943 |
97 | TNIK | 0.21095211 |
98 | ARAF | 0.20636555 |
99 | MAPK10 | 0.19750627 |
100 | PRKAA1 | 0.19551087 |
101 | PIM2 | 0.19258245 |
102 | MAPK14 | 0.18696289 |
103 | TAOK1 | 0.18515404 |
104 | MTOR | 0.18366638 |
105 | TAOK3 | 0.17852254 |
106 | MAP3K9 | 0.17060212 |
107 | ATM | 0.16831595 |
108 | PAK2 | 0.16151745 |
109 | MARK2 | 0.15971044 |
110 | WNK3 | 0.15937147 |
111 | MAPK11 | 0.15921600 |
112 | PRKCB | 0.13510921 |
113 | BRSK2 | 0.12652450 |
114 | PRKACB | 0.12519151 |
115 | AKT1 | 0.12325498 |
116 | MAPKAPK5 | 0.11992272 |
117 | SGK2 | 0.11780655 |
118 | PLK1 | 0.11734627 |
119 | PKN1 | 0.11598367 |
120 | RPS6KC1 | 0.11596851 |
121 | RPS6KL1 | 0.11596851 |
122 | PTK6 | 0.11039724 |
123 | MAP3K5 | 0.10991351 |
124 | NEK6 | 0.10968567 |
125 | PRKG1 | 0.10786244 |
126 | BLK | 0.10623576 |
127 | MARK1 | 0.10447751 |
128 | CLK1 | 0.10180630 |
129 | RPS6KA6 | 0.10137104 |
130 | NUAK1 | 0.09876401 |
131 | ATR | 0.09866886 |
132 | PRKCZ | 0.09590008 |
133 | CAMK2A | 0.08647189 |
134 | WEE1 | 0.08431670 |
135 | CDK15 | 0.08418963 |
136 | MAP3K11 | 0.08418439 |
137 | MAP3K1 | 0.08408796 |
138 | PRKCA | 0.07112862 |
139 | CSNK2A1 | 0.06946919 |
140 | BUB1 | 0.06929909 |
141 | CDK11A | 0.06484508 |
142 | PRKCD | 0.05639239 |
143 | CDK18 | 0.05545744 |
144 | CSNK1D | 0.05538787 |
145 | STK11 | 0.05349355 |
146 | RPS6KB1 | 0.05288804 |
147 | YES1 | 0.04940740 |
148 | MYLK | 0.03639062 |
149 | PRKACG | 0.03609073 |
150 | RPS6KA1 | 0.03534669 |
151 | DDR2 | 0.03368985 |
152 | MAPK8 | 0.03229280 |
153 | CDK12 | 0.03021642 |
154 | CSNK2A2 | 0.02660874 |
155 | GSK3B | 0.02563925 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 6.85619609 |
2 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 4.94558975 |
3 | Olfactory transduction_Homo sapiens_hsa04740 | 4.17498380 |
4 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 4.10191416 |
5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.06055439 |
6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.04850276 |
7 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.91775735 |
8 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.86179323 |
9 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.78811229 |
10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.49892409 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.41295447 |
12 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 2.40792135 |
13 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 2.32270181 |
14 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.31394441 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.14658784 |
16 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.95942200 |
17 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.94415033 |
18 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.88898378 |
19 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.82648922 |
20 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.80759389 |
21 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.80292925 |
22 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.79097574 |
23 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.63781544 |
24 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.60554445 |
25 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.52764144 |
26 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.52626616 |
27 | Mineral absorption_Homo sapiens_hsa04978 | 1.52494283 |
28 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.52468190 |
29 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.51983775 |
30 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.50248785 |
31 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.46731825 |
32 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.46004401 |
33 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.45757539 |
34 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.43601623 |
35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.43472656 |
36 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.42962646 |
37 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.42128304 |
38 | Phototransduction_Homo sapiens_hsa04744 | 1.37844203 |
39 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.35280251 |
40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.29367400 |
41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.24097787 |
42 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.23822520 |
43 | Asthma_Homo sapiens_hsa05310 | 1.13344269 |
44 | Huntingtons disease_Homo sapiens_hsa05016 | 1.10361176 |
45 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.08458576 |
46 | Carbon metabolism_Homo sapiens_hsa01200 | 1.08408763 |
47 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.07677717 |
48 | Allograft rejection_Homo sapiens_hsa05330 | 1.05366718 |
49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03881682 |
50 | Nicotine addiction_Homo sapiens_hsa05033 | 1.03579334 |
51 | Morphine addiction_Homo sapiens_hsa05032 | 1.01611435 |
52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.01274048 |
53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00882877 |
54 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.00119102 |
55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.99541385 |
56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.99358328 |
57 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.98875758 |
58 | Purine metabolism_Homo sapiens_hsa00230 | 0.97260124 |
59 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.93459565 |
60 | Renin secretion_Homo sapiens_hsa04924 | 0.93100289 |
61 | Influenza A_Homo sapiens_hsa05164 | 0.90975747 |
62 | Bile secretion_Homo sapiens_hsa04976 | 0.89454071 |
63 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.85188467 |
64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82938965 |
65 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.82648337 |
66 | Insulin secretion_Homo sapiens_hsa04911 | 0.81639859 |
67 | ABC transporters_Homo sapiens_hsa02010 | 0.80335855 |
68 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.79374152 |
69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.78340700 |
70 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77456899 |
71 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.74381370 |
72 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.73764236 |
73 | Taste transduction_Homo sapiens_hsa04742 | 0.73615094 |
74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72848833 |
75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70579982 |
76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.68494823 |
77 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.65754358 |
78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.65218426 |
79 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.64980419 |
80 | Other glycan degradation_Homo sapiens_hsa00511 | 0.64979173 |
81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60672940 |
82 | Cell cycle_Homo sapiens_hsa04110 | 0.60109372 |
83 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.59235674 |
84 | RNA transport_Homo sapiens_hsa03013 | 0.59076070 |
85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.58011240 |
86 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.57477484 |
87 | Salivary secretion_Homo sapiens_hsa04970 | 0.57111560 |
88 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.57076116 |
89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.56643881 |
90 | Long-term potentiation_Homo sapiens_hsa04720 | 0.55967616 |
91 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.54928025 |
92 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54289302 |
93 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.53175335 |
94 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52252622 |
95 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.52026759 |
96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51593904 |
97 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.51588275 |
98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51434679 |
99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49152303 |
100 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.48196578 |
101 | Legionellosis_Homo sapiens_hsa05134 | 0.47934779 |
102 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.46711036 |
103 | Base excision repair_Homo sapiens_hsa03410 | 0.44696508 |
104 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.44038066 |
105 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43022672 |
106 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.41428129 |
107 | GABAergic synapse_Homo sapiens_hsa04727 | 0.41266348 |
108 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39977225 |
109 | Cocaine addiction_Homo sapiens_hsa05030 | 0.38538657 |
110 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.37878578 |
111 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37854240 |
112 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.37428661 |
113 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.35872759 |
114 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.35669695 |
115 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.35497678 |
116 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.35472972 |
117 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.35270674 |
118 | Malaria_Homo sapiens_hsa05144 | 0.32226003 |
119 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31806216 |
120 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.31261330 |
121 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.31116746 |
122 | Circadian entrainment_Homo sapiens_hsa04713 | 0.31080544 |
123 | Tight junction_Homo sapiens_hsa04530 | 0.30623759 |
124 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.30364877 |
125 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.30302110 |
126 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.30224201 |
127 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.28764147 |
128 | Endocytosis_Homo sapiens_hsa04144 | 0.27947331 |
129 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.27463440 |
130 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.27110830 |
131 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.25400579 |
132 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.24065348 |
133 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22570758 |
134 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.22439833 |
135 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.21743833 |
136 | Adherens junction_Homo sapiens_hsa04520 | 0.21734128 |
137 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.21665017 |
138 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.18967852 |
139 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.18369848 |
140 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.18277613 |
141 | Alcoholism_Homo sapiens_hsa05034 | 0.15004747 |
142 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.14182860 |