TRIM46

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.21233701
2synaptic vesicle maturation (GO:0016188)5.88343958
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.64742873
4locomotory exploration behavior (GO:0035641)5.63844471
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.54875510
6vocalization behavior (GO:0071625)5.53377103
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.45400774
8response to pheromone (GO:0019236)5.42198668
9synaptic vesicle exocytosis (GO:0016079)5.21288107
10regulation of glutamate receptor signaling pathway (GO:1900449)5.16693676
11synaptic vesicle docking involved in exocytosis (GO:0016081)5.08292092
12protein localization to synapse (GO:0035418)5.07200118
13regulation of synaptic vesicle exocytosis (GO:2000300)4.92070210
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.89500921
15neuron cell-cell adhesion (GO:0007158)4.84827687
16glutamate secretion (GO:0014047)4.82685753
17regulation of synapse structural plasticity (GO:0051823)4.74496957
18exploration behavior (GO:0035640)4.67276939
19nucleobase catabolic process (GO:0046113)4.61846247
20regulation of neuronal synaptic plasticity (GO:0048168)4.61093950
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.54226489
22layer formation in cerebral cortex (GO:0021819)4.51152384
23regulation of synaptic vesicle transport (GO:1902803)4.45067820
24synaptic transmission, glutamatergic (GO:0035249)4.34838333
25dendritic spine morphogenesis (GO:0060997)4.29588929
26glutamate receptor signaling pathway (GO:0007215)4.28153850
27neurotransmitter secretion (GO:0007269)4.27233628
28presynaptic membrane organization (GO:0097090)4.24854463
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.22438145
30neurotransmitter-gated ion channel clustering (GO:0072578)4.13973562
31neuron recognition (GO:0008038)4.03452342
32neuron-neuron synaptic transmission (GO:0007270)4.00032541
33negative regulation of synaptic transmission, GABAergic (GO:0032229)3.97672019
34neuronal action potential propagation (GO:0019227)3.97424397
35axonal fasciculation (GO:0007413)3.90291294
36regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.89640942
37long-term memory (GO:0007616)3.89235293
38positive regulation of membrane potential (GO:0045838)3.88404273
39postsynaptic membrane organization (GO:0001941)3.82658201
40positive regulation of synaptic transmission, GABAergic (GO:0032230)3.82146620
41positive regulation of synapse maturation (GO:0090129)3.81900971
42auditory behavior (GO:0031223)3.81739954
43regulation of excitatory postsynaptic membrane potential (GO:0060079)3.80402402
44establishment of mitochondrion localization (GO:0051654)3.80254815
45acrosome reaction (GO:0007340)3.79190639
46proline transport (GO:0015824)3.75033476
47regulation of dendritic spine morphogenesis (GO:0061001)3.72145270
48protein polyglutamylation (GO:0018095)3.69679099
49regulation of postsynaptic membrane potential (GO:0060078)3.65656272
50behavioral response to nicotine (GO:0035095)3.63151858
51dendrite morphogenesis (GO:0048813)3.61955854
52positive regulation of neurotransmitter secretion (GO:0001956)3.61328109
53regulation of synaptic plasticity (GO:0048167)3.56007127
54membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.55597060
55regulation of vesicle fusion (GO:0031338)3.50816247
56cell migration in hindbrain (GO:0021535)3.49653451
57positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.46359107
58positive regulation of neurotransmitter transport (GO:0051590)3.45936117
59gamma-aminobutyric acid transport (GO:0015812)3.45671375
60neurofilament cytoskeleton organization (GO:0060052)3.43494216
61response to auditory stimulus (GO:0010996)3.43025217
62transmission of nerve impulse (GO:0019226)3.41659883
63activation of protein kinase A activity (GO:0034199)3.41082258
64regulation of synaptic transmission, glutamatergic (GO:0051966)3.40617907
65sperm motility (GO:0030317)3.40609508
66regulation of neurotransmitter secretion (GO:0046928)3.39114385
67prepulse inhibition (GO:0060134)3.38577141
68G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.38288477
69calcium ion-dependent exocytosis (GO:0017156)3.38003397
70neuromuscular process controlling balance (GO:0050885)3.36521031
71neurotransmitter transport (GO:0006836)3.35091788
72single strand break repair (GO:0000012)3.32032757
73positive regulation of dendritic spine development (GO:0060999)3.28928685
74alanine transport (GO:0032328)3.28557052
75long-term synaptic potentiation (GO:0060291)3.24103291
76synaptic vesicle endocytosis (GO:0048488)3.24096994
77dopamine receptor signaling pathway (GO:0007212)3.23887179
78central nervous system projection neuron axonogenesis (GO:0021952)3.22790871
79behavioral response to ethanol (GO:0048149)3.19149481
80neuronal ion channel clustering (GO:0045161)3.18358648
81membrane hyperpolarization (GO:0060081)3.17825493
82learning (GO:0007612)3.17136979
83regulation of neurotransmitter levels (GO:0001505)3.17050320
84behavioral fear response (GO:0001662)3.16689898
85behavioral defense response (GO:0002209)3.16689898
86regulation of dendritic spine development (GO:0060998)3.16370002
87negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.16156129
88positive regulation of dendritic spine morphogenesis (GO:0061003)3.16055627
89nonmotile primary cilium assembly (GO:0035058)3.15726634
90membrane depolarization (GO:0051899)3.15354675
91epithelial cilium movement (GO:0003351)3.14633364
92G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.14331417
93response to histamine (GO:0034776)3.13694898
94innervation (GO:0060384)3.13136728
95regulation of microtubule-based movement (GO:0060632)3.13072674
96adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.12862500
97membrane depolarization during action potential (GO:0086010)3.11944752
98cerebellar Purkinje cell differentiation (GO:0021702)3.11915221
99regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11539457
100regulation of neurotransmitter transport (GO:0051588)3.11411630
101negative regulation of microtubule polymerization (GO:0031115)3.11288029
102regulation of cilium movement (GO:0003352)3.09842606
103mechanosensory behavior (GO:0007638)3.08759127
104cellular potassium ion homeostasis (GO:0030007)3.07992726
105dendritic spine organization (GO:0097061)3.07754951
106presynaptic membrane assembly (GO:0097105)3.06737718
107cell communication by electrical coupling (GO:0010644)3.06297042
108synapse assembly (GO:0007416)3.04362424
109positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.03453026
110fear response (GO:0042596)3.00815816
111intraspecies interaction between organisms (GO:0051703)2.99669913
112social behavior (GO:0035176)2.99669913
113vesicle transport along microtubule (GO:0047496)2.99125497
114regulation of glutamate secretion (GO:0014048)2.99018778
115regulation of synaptic transmission (GO:0050804)2.96609738
116positive regulation of synapse assembly (GO:0051965)2.96379009
117positive regulation of synaptic transmission (GO:0050806)2.96274242
118pyrimidine nucleobase catabolic process (GO:0006208)2.95426269
119establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.95024116
120mitochondrion transport along microtubule (GO:0047497)2.95024116
121gamma-aminobutyric acid signaling pathway (GO:0007214)2.94285025
122startle response (GO:0001964)2.92047639
123spinal cord development (GO:0021510)2.85161643
124neuromuscular synaptic transmission (GO:0007274)2.85035791
125regulation of feeding behavior (GO:0060259)2.80901510
126negative regulation of cytosolic calcium ion concentration (GO:0051481)2.80749003
127substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.80178261
128substrate-independent telencephalic tangential migration (GO:0021826)2.80178261
129protein localization to cilium (GO:0061512)2.79227465
130appendage development (GO:0048736)2.70577919
131limb development (GO:0060173)2.70577919
132positive regulation of mitochondrial fission (GO:0090141)2.69182720
133regulation of synapse maturation (GO:0090128)2.68357198
134calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.68316866
135behavioral response to cocaine (GO:0048148)2.66245057
136brain morphogenesis (GO:0048854)2.65388157
137epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.62178769
138regulation of synaptic transmission, GABAergic (GO:0032228)2.61292484
139regulation of respiratory system process (GO:0044065)2.60090207

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.79471877
2GBX2_23144817_ChIP-Seq_PC3_Human3.41829370
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.17233669
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.13738966
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.04813696
6REST_21632747_ChIP-Seq_MESCs_Mouse2.91073342
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.81020313
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.77836720
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.75438271
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.75438271
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.74829581
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.64767761
13SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.60393472
14DROSHA_22980978_ChIP-Seq_HELA_Human2.59777477
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.56710068
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52196310
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51733736
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.46477290
19* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.44746645
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.43815529
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.40671219
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.38035980
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.34810631
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.29582157
25EED_16625203_ChIP-ChIP_MESCs_Mouse2.24822987
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.24774410
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.11546062
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.01686973
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.91249892
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.74088161
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.67478129
32AR_21572438_ChIP-Seq_LNCaP_Human1.65743259
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63645208
34ZNF274_21170338_ChIP-Seq_K562_Hela1.57382829
35RBPJ_22232070_ChIP-Seq_NCS_Mouse1.57232474
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.54178752
37VDR_22108803_ChIP-Seq_LS180_Human1.51858313
38FUS_26573619_Chip-Seq_HEK293_Human1.46159712
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46059940
40RING1B_27294783_Chip-Seq_ESCs_Mouse1.45831482
41SMAD4_21799915_ChIP-Seq_A2780_Human1.43557520
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39988802
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38129940
44DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35536264
45RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.34142833
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.31605155
47CBP_20019798_ChIP-Seq_JUKART_Human1.28389588
48IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28389588
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26402484
50* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.25508141
51TAF15_26573619_Chip-Seq_HEK293_Human1.24858174
52SOX2_21211035_ChIP-Seq_LN229_Gbm1.23808583
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.23103890
54RING1B_27294783_Chip-Seq_NPCs_Mouse1.22166350
55NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22063781
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.20307091
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.20286602
58AR_19668381_ChIP-Seq_PC3_Human1.19683303
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19434437
60P300_19829295_ChIP-Seq_ESCs_Human1.19105214
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17081273
62* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.16927502
63MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16507085
64TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15024690
65KDM2B_26808549_Chip-Seq_K562_Human1.14282693
66AR_25329375_ChIP-Seq_VCAP_Human1.14086954
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13793398
68WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13697007
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.13342384
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13100177
71EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.12853204
72P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12670244
73RNF2_27304074_Chip-Seq_NSC_Mouse1.11887348
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09361756
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06807473
76ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06577838
77STAT3_23295773_ChIP-Seq_U87_Human1.06036576
78RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05229582
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02082740
80SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02035799
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.01768776
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00752211
83YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00729531
84VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99842002
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99639128
86ARNT_22903824_ChIP-Seq_MCF-7_Human0.99239214
87TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98538832
88OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98397442
89TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98368178
90OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98324888
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98099864
92KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97585130
93IGF1R_20145208_ChIP-Seq_DFB_Human0.97274961
94AHR_22903824_ChIP-Seq_MCF-7_Human0.96963833
95SALL1_21062744_ChIP-ChIP_HESCs_Human0.96743078
96GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94260887
97TCF4_23295773_ChIP-Seq_U87_Human0.93239572
98ER_23166858_ChIP-Seq_MCF-7_Human0.93178637
99* CTCF_27219007_Chip-Seq_Bcells_Human0.93152759
100ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93035979
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91775249
102TET1_21490601_ChIP-Seq_MESCs_Mouse0.91615676
103SMAD3_21741376_ChIP-Seq_ESCs_Human0.91296398
104WDR5_24793694_ChIP-Seq_LNCAP_Human0.91137481
105TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91125453
106GATA1_26923725_Chip-Seq_HPCs_Mouse0.91068693
107SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90760640
108ZFP281_27345836_Chip-Seq_ESCs_Mouse0.90578070
109ERA_21632823_ChIP-Seq_H3396_Human0.90575547
110RUNX2_22187159_ChIP-Seq_PCA_Human0.90559931
111CDX2_19796622_ChIP-Seq_MESCs_Mouse0.89395385
112HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.89325503
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89165864
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88073679
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88073679
116PIAS1_25552417_ChIP-Seq_VCAP_Human0.87623125
117SMAD4_21741376_ChIP-Seq_EPCs_Human0.86868252
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.86375267
119SMAD4_21741376_ChIP-Seq_HESCs_Human0.86071997
120KDM2B_26808549_Chip-Seq_REH_Human0.86056546
121PRDM14_20953172_ChIP-Seq_ESCs_Human0.85102845
122FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.84979189
123CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84743846
124MYC_19829295_ChIP-Seq_ESCs_Human0.84316036
125GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83910772
126JUN_21703547_ChIP-Seq_K562_Human0.82004312
127SMAD_19615063_ChIP-ChIP_OVARY_Human0.81625080
128SMAD3_21741376_ChIP-Seq_HESCs_Human0.80283981
129TP53_20018659_ChIP-ChIP_R1E_Mouse0.79452805

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.67429431
2MP0003880_abnormal_central_pattern4.69857484
3MP0003635_abnormal_synaptic_transmissio4.18853709
4MP0004270_analgesia3.75142621
5MP0002063_abnormal_learning/memory/cond3.40913786
6MP0002822_catalepsy3.37397457
7MP0009745_abnormal_behavioral_response3.37056407
8MP0001968_abnormal_touch/_nociception3.11077263
9MP0005423_abnormal_somatic_nervous3.10807621
10MP0002064_seizures2.96864901
11MP0002572_abnormal_emotion/affect_behav2.83155464
12MP0002734_abnormal_mechanical_nocicepti2.63698767
13MP0009046_muscle_twitch2.60948558
14MP0002735_abnormal_chemical_nociception2.51129822
15MP0002736_abnormal_nociception_after2.39227701
16MP0002272_abnormal_nervous_system2.39101560
17MP0001486_abnormal_startle_reflex2.37453740
18MP0002733_abnormal_thermal_nociception2.21157177
19MP0001501_abnormal_sleep_pattern2.10485980
20MP0000778_abnormal_nervous_system2.09351693
21MP0001440_abnormal_grooming_behavior2.06519755
22MP0001970_abnormal_pain_threshold2.01951647
23MP0004858_abnormal_nervous_system2.00088134
24MP0008877_abnormal_DNA_methylation1.98416713
25MP0005410_abnormal_fertilization1.97651243
26MP0002184_abnormal_innervation1.95681219
27MP0004811_abnormal_neuron_physiology1.91198593
28MP0006276_abnormal_autonomic_nervous1.89776171
29MP0002557_abnormal_social/conspecific_i1.89263062
30MP0002909_abnormal_adrenal_gland1.88376153
31MP0009780_abnormal_chondrocyte_physiolo1.86953082
32MP0008569_lethality_at_weaning1.86407877
33MP0002067_abnormal_sensory_capabilities1.84949113
34MP0004924_abnormal_behavior1.72314709
35MP0005386_behavior/neurological_phenoty1.72314709
36MP0003329_amyloid_beta_deposits1.71498778
37MP0003787_abnormal_imprinting1.68915530
38MP0001986_abnormal_taste_sensitivity1.66938164
39MP0005645_abnormal_hypothalamus_physiol1.63132571
40MP0000955_abnormal_spinal_cord1.60635188
41MP0001529_abnormal_vocalization1.57928290
42MP0001984_abnormal_olfaction1.55616969
43MP0003879_abnormal_hair_cell1.53147937
44MP0005646_abnormal_pituitary_gland1.48924046
45MP0004133_heterotaxia1.44270886
46MP0002882_abnormal_neuron_morphology1.43835888
47MP0002653_abnormal_ependyma_morphology1.43341418
48MP0003122_maternal_imprinting1.40846432
49MP0001905_abnormal_dopamine_level1.39074431
50MP0002066_abnormal_motor_capabilities/c1.37651623
51MP0004885_abnormal_endolymph1.37063957
52MP0001502_abnormal_circadian_rhythm1.36649922
53MP0008789_abnormal_olfactory_epithelium1.36042710
54MP0000049_abnormal_middle_ear1.31363567
55MP0001188_hyperpigmentation1.28833504
56MP0003698_abnormal_male_reproductive1.19814285
57MP0002152_abnormal_brain_morphology1.18794780
58MP0000569_abnormal_digit_pigmentation1.18177362
59MP0005377_hearing/vestibular/ear_phenot1.15788910
60MP0003878_abnormal_ear_physiology1.15788910
61MP0004142_abnormal_muscle_tone1.14482247
62MP0003633_abnormal_nervous_system1.12927257
63MP0006072_abnormal_retinal_apoptosis1.12223716
64MP0000026_abnormal_inner_ear1.12174246
65MP0005253_abnormal_eye_physiology1.10558269
66MP0010386_abnormal_urinary_bladder1.07460487
67MP0003119_abnormal_digestive_system1.05674011
68MP0003938_abnormal_ear_development1.02733896
69MP0003011_delayed_dark_adaptation1.02503351
70MP0003283_abnormal_digestive_organ1.00827320
71MP0002069_abnormal_eating/drinking_beha0.99104229
72MP0008961_abnormal_basal_metabolism0.96944405
73MP0003631_nervous_system_phenotype0.96187679
74MP0000631_abnormal_neuroendocrine_gland0.94678790
75MP0000751_myopathy0.90512868
76MP0005394_taste/olfaction_phenotype0.89985396
77MP0005499_abnormal_olfactory_system0.89985396
78MP0008995_early_reproductive_senescence0.89190828
79MP0008872_abnormal_physiological_respon0.87206418
80MP0000013_abnormal_adipose_tissue0.85017091
81MP0004085_abnormal_heartbeat0.83559986
82MP0001485_abnormal_pinna_reflex0.83089503
83MP0001177_atelectasis0.81506573
84MP0004742_abnormal_vestibular_system0.78477142
85MP0008874_decreased_physiological_sensi0.78329304
86MP0002229_neurodegeneration0.77996173
87MP0001929_abnormal_gametogenesis0.76761563
88MP0005409_darkened_coat_color0.75568177
89MP0005535_abnormal_body_temperature0.74173032
90MP0005084_abnormal_gallbladder_morpholo0.73944784
91MP0002752_abnormal_somatic_nervous0.73818468
92MP0003861_abnormal_nervous_system0.73775007
93MP0003123_paternal_imprinting0.73328152
94MP0010234_abnormal_vibrissa_follicle0.73296618
95MP0003075_altered_response_to0.73026222
96MP0005670_abnormal_white_adipose0.72887309
97MP0003634_abnormal_glial_cell0.72099599
98MP0005195_abnormal_posterior_eye0.71671577
99MP0002638_abnormal_pupillary_reflex0.71224953
100MP0006292_abnormal_olfactory_placode0.70580380
101MP0002938_white_spotting0.68744268
102MP0001963_abnormal_hearing_physiology0.68086911
103MP0001664_abnormal_digestion0.66920746
104MP0003632_abnormal_nervous_system0.66337115
105MP0003136_yellow_coat_color0.66127382
106MP0002234_abnormal_pharynx_morphology0.65653219
107MP0000604_amyloidosis0.65221381
108MP0002210_abnormal_sex_determination0.64609963
109MP0002161_abnormal_fertility/fecundity0.64250738
110MP0001943_abnormal_respiration0.59261186
111MP0003137_abnormal_impulse_conducting0.59059209
112MP0005551_abnormal_eye_electrophysiolog0.58981484
113MP0002751_abnormal_autonomic_nervous0.57603152
114MP0002876_abnormal_thyroid_physiology0.57555977
115MP0005187_abnormal_penis_morphology0.56554487
116MP0010769_abnormal_survival0.56389857
117MP0002102_abnormal_ear_morphology0.56130951
118MP0001299_abnormal_eye_distance/0.56010677
119MP0001348_abnormal_lacrimal_gland0.54672120
120MP0002082_postnatal_lethality0.54609637
121MP0010770_preweaning_lethality0.54609637
122MP0004145_abnormal_muscle_electrophysio0.53955169
123MP0003121_genomic_imprinting0.53721131
124MP0010768_mortality/aging0.53092614
125MP0003956_abnormal_body_size0.51064844
126MP0002090_abnormal_vision0.50137392
127MP0004510_myositis0.49999330

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.15934383
2Focal motor seizures (HP:0011153)6.82741445
3Focal seizures (HP:0007359)5.56040701
4Visual hallucinations (HP:0002367)4.91631981
5Epileptic encephalopathy (HP:0200134)4.57126732
6Atonic seizures (HP:0010819)3.99353668
7Febrile seizures (HP:0002373)3.98727470
8Progressive cerebellar ataxia (HP:0002073)3.91626744
9Ankle clonus (HP:0011448)3.87608453
10Supranuclear gaze palsy (HP:0000605)3.84100159
11Broad-based gait (HP:0002136)3.58251582
12Absence seizures (HP:0002121)3.57934826
13Action tremor (HP:0002345)3.37736148
14Generalized tonic-clonic seizures (HP:0002069)3.35225791
15Poor eye contact (HP:0000817)3.34347113
16Dialeptic seizures (HP:0011146)3.33271331
17Mutism (HP:0002300)3.30589279
18Impaired vibration sensation in the lower limbs (HP:0002166)3.29269798
19Abnormality of the lower motor neuron (HP:0002366)3.25937213
20Amblyopia (HP:0000646)3.20772041
21Truncal ataxia (HP:0002078)3.14870121
22Anxiety (HP:0000739)3.07819602
23Papilledema (HP:0001085)3.05355521
24Nephronophthisis (HP:0000090)3.05252130
25Limb dystonia (HP:0002451)3.04848441
26Depression (HP:0000716)3.02408573
27Abnormal eating behavior (HP:0100738)3.00690386
28Torticollis (HP:0000473)2.99643507
29Hyperventilation (HP:0002883)2.97026960
30Urinary bladder sphincter dysfunction (HP:0002839)2.96780651
31Gaze-evoked nystagmus (HP:0000640)2.90446472
32Abnormal social behavior (HP:0012433)2.89775408
33Impaired social interactions (HP:0000735)2.89775408
34Pancreatic fibrosis (HP:0100732)2.88874313
35Stereotypic behavior (HP:0000733)2.81532233
36Focal dystonia (HP:0004373)2.80875040
37Pancreatic cysts (HP:0001737)2.77816332
38Urinary urgency (HP:0000012)2.76487279
39Drooling (HP:0002307)2.73694625
40Excessive salivation (HP:0003781)2.73694625
41Spastic gait (HP:0002064)2.68914790
42Retinal dysplasia (HP:0007973)2.68881108
43Hemiparesis (HP:0001269)2.68667545
44Dysdiadochokinesis (HP:0002075)2.67671101
45Medial flaring of the eyebrow (HP:0010747)2.65753122
46Epileptiform EEG discharges (HP:0011182)2.62506478
47Progressive inability to walk (HP:0002505)2.62075760
48Molar tooth sign on MRI (HP:0002419)2.60266767
49Abnormality of midbrain morphology (HP:0002418)2.60266767
50True hermaphroditism (HP:0010459)2.59109911
51Polyphagia (HP:0002591)2.58492608
52Dysmetria (HP:0001310)2.57274089
53EEG with generalized epileptiform discharges (HP:0011198)2.56475201
54Congenital stationary night blindness (HP:0007642)2.56160871
55Cerebral inclusion bodies (HP:0100314)2.53716048
56Impaired smooth pursuit (HP:0007772)2.52785894
57Craniofacial dystonia (HP:0012179)2.52634776
58Genetic anticipation (HP:0003743)2.51950093
59Postural instability (HP:0002172)2.49628475
60Amyotrophic lateral sclerosis (HP:0007354)2.49514017
61Hypsarrhythmia (HP:0002521)2.48676966
62Congenital primary aphakia (HP:0007707)2.46750860
63Pachygyria (HP:0001302)2.44162485
64Agitation (HP:0000713)2.42878465
65Neurofibrillary tangles (HP:0002185)2.42863812
66Bradykinesia (HP:0002067)2.40024776
67Abnormal rod and cone electroretinograms (HP:0008323)2.39501370
68Abnormality of the renal medulla (HP:0100957)2.39234926
69Megalencephaly (HP:0001355)2.38569711
70Genital tract atresia (HP:0001827)2.38154561
71Nephrogenic diabetes insipidus (HP:0009806)2.36809962
72Obstructive sleep apnea (HP:0002870)2.36663253
73Vaginal atresia (HP:0000148)2.36254629
74Abnormality of the corticospinal tract (HP:0002492)2.31578495
75Diplopia (HP:0000651)2.31127060
76Abnormality of binocular vision (HP:0011514)2.31127060
77Severe visual impairment (HP:0001141)2.29975360
78Chronic hepatic failure (HP:0100626)2.26816440
79Bony spicule pigmentary retinopathy (HP:0007737)2.24944655
80Lower limb muscle weakness (HP:0007340)2.21093926
81Attenuation of retinal blood vessels (HP:0007843)2.20944385
82Type II lissencephaly (HP:0007260)2.19580779
83Insomnia (HP:0100785)2.18487499
84Abnormality of the labia minora (HP:0012880)2.18337024
85Pointed chin (HP:0000307)2.17673061
86Annular pancreas (HP:0001734)2.16285744
87Insidious onset (HP:0003587)2.15159479
88Termporal pattern (HP:0011008)2.15159479
89Scanning speech (HP:0002168)2.15152400
90Fetal akinesia sequence (HP:0001989)2.14911373
91Abnormality of ocular smooth pursuit (HP:0000617)2.13358155
92Cortical dysplasia (HP:0002539)2.10172957
93Hypoventilation (HP:0002791)2.09947638
94Pendular nystagmus (HP:0012043)2.08649984
95Cystic liver disease (HP:0006706)2.08358116
96Failure to thrive in infancy (HP:0001531)2.07090153
97Spastic tetraplegia (HP:0002510)2.06316402
98Protruding tongue (HP:0010808)2.05219249
99Optic nerve hypoplasia (HP:0000609)2.04719665
100Apathy (HP:0000741)2.02035486
101Hemiplegia (HP:0002301)2.01493455
102Exotropia (HP:0000577)2.01423431
103Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.01277368
104Occipital encephalocele (HP:0002085)2.00867266
105Lower limb amyotrophy (HP:0007210)2.00523517
106Inappropriate behavior (HP:0000719)2.00517121
107Absent speech (HP:0001344)2.00445702
108Intestinal atresia (HP:0011100)2.00093891
109Sclerocornea (HP:0000647)1.99498332
110Sleep apnea (HP:0010535)1.97510604
111Anencephaly (HP:0002323)1.97382697
112Inability to walk (HP:0002540)1.96770288
113Clonus (HP:0002169)1.96226943
114Hypoplasia of the brainstem (HP:0002365)1.96162546
115Aplasia/Hypoplasia of the brainstem (HP:0007362)1.96162546
116Intention tremor (HP:0002080)1.95436742
117Abnormal respiratory epithelium morphology (HP:0012253)1.94687245
118Abnormal respiratory motile cilium morphology (HP:0005938)1.94687245
119Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.93974511
120Impaired vibratory sensation (HP:0002495)1.93964300
121Abnormality of macular pigmentation (HP:0008002)1.93496061
122Poor coordination (HP:0002370)1.93259663
123Ventricular fibrillation (HP:0001663)1.92254656
124Anophthalmia (HP:0000528)1.90714904
125Esotropia (HP:0000565)1.89388143
126Pheochromocytoma (HP:0002666)1.88328785
127Gait imbalance (HP:0002141)1.88059478
128Lissencephaly (HP:0001339)1.86015700
129Psychosis (HP:0000709)1.83917559
130Optic nerve coloboma (HP:0000588)1.83446146
131Specific learning disability (HP:0001328)1.83222044
132Incomplete penetrance (HP:0003829)1.82685983
133Anosmia (HP:0000458)1.82294091
134Renal dysplasia (HP:0000110)1.82293940
135Lower limb asymmetry (HP:0100559)1.82172401
136Akinesia (HP:0002304)1.81880549
137Abnormal EKG (HP:0003115)1.80260777
138Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.79763750
139Poor suck (HP:0002033)1.78843846
140Morphological abnormality of the middle ear (HP:0008609)1.77919809
141Rapidly progressive (HP:0003678)1.77481264
142Status epilepticus (HP:0002133)1.76778758
143Neuronal loss in central nervous system (HP:0002529)1.76713387
144Hypoplasia of the corpus callosum (HP:0002079)1.75681930
145Degeneration of the lateral corticospinal tracts (HP:0002314)1.74917751
146Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.74917751
147Cerebral hypomyelination (HP:0006808)1.74668509
148Abnormal hair whorl (HP:0010721)1.74329666
149Narrow forehead (HP:0000341)1.74283968
150Dynein arm defect of respiratory motile cilia (HP:0012255)1.72813139
151Absent/shortened dynein arms (HP:0200106)1.72813139
152Abnormality of the aortic arch (HP:0012303)1.70214756
153Morphological abnormality of the pyramidal tract (HP:0002062)1.69858036
154Postaxial hand polydactyly (HP:0001162)1.68520638
155Keratoconus (HP:0000563)1.67006400
156Increased corneal curvature (HP:0100692)1.67006400
157Abnormal biliary tract physiology (HP:0012439)1.66443428

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.76200600
2EPHA44.40628549
3MARK14.21706945
4MAP3K94.13241545
5MAP3K42.71377371
6MINK12.69558954
7DAPK22.66975782
8MAP2K72.64904647
9MAP4K22.52894965
10NTRK22.35992760
11PRKD32.29970979
12TNIK2.28458487
13BMPR1B2.22631134
14INSRR2.08940524
15KSR22.01877966
16PAK61.94849602
17KSR11.81911836
18SIK21.79767516
19MAPK131.79217717
20CAMKK11.73927658
21DAPK11.62707950
22MAP3K121.61959358
23MAP2K41.60617990
24CASK1.59749535
25CDK51.56005806
26ARAF1.55876375
27NTRK11.51455857
28BCR1.49726717
29FRK1.42515957
30RIPK41.33312133
31TRIM281.27119088
32ADRBK21.25948210
33STK161.25673612
34GRK51.22432975
35PNCK1.20900232
36UHMK11.20783717
37PHKG21.19597968
38PHKG11.19597968
39CAMKK21.19003885
40FES1.18883662
41PRPF4B1.17291307
42TYRO31.16135691
43PLK21.15860862
44PRKCG1.09575093
45PLK41.08970948
46MAP3K21.08782216
47GRK11.07504388
48FGFR21.06629480
49STK381.04594815
50TAOK11.04543585
51CDK190.99142043
52MARK20.98863254
53EPHA30.98653365
54CAMK10.98614502
55TESK10.91425415
56LATS20.90868064
57CDK180.90679635
58MAPK150.90213343
59CDK150.87912448
60CAMK2A0.87766601
61SGK4940.87270312
62SGK2230.87270312
63MUSK0.86346190
64MAP3K130.86188814
65WNK40.85281700
66CDK140.83343625
67PKN10.82650480
68RET0.81324091
69CSNK1G30.79273045
70CDK11A0.78678833
71PAK30.77871387
72ERBB30.77626254
73DYRK1B0.76698086
74RAF10.76642603
75PRKCH0.76445279
76DYRK1A0.75605219
77DDR20.74228652
78STK110.73128188
79CSNK1G20.71771966
80SGK20.71354072
81EPHB20.71273513
82PTK2B0.69574841
83CAMK2B0.68922437
84OXSR10.68651828
85RPS6KA20.65851201
86CAMK1G0.65083222
87DYRK20.64896071
88CSNK1A1L0.63078549
89CSNK1G10.60249423
90AKT30.59851702
91SGK30.59108868
92MAP3K10.59096561
93ZAK0.58316833
94PRKCZ0.57746614
95DYRK30.57332063
96CAMK1D0.56372295
97SGK10.55697121
98SIK30.55675502
99BCKDK0.52422335
100CDC42BPA0.51990237
101CAMK40.51755077
102LMTK20.50592849
103ALK0.49279741
104PRKG10.47165883
105FER0.45992600
106BMPR20.45223587
107ADRBK10.44770494
108PRKACA0.44406624
109DAPK30.44258199
110PRKCE0.43601544
111PRKAA10.43420972
112FYN0.42766983
113RPS6KA40.41288138
114PDK10.40969943
115RPS6KA30.40922973
116FGR0.40717661
117WNK30.40363600
118ERBB20.40172292
119PRKD20.38836976
120PDPK10.38705066
121MAP2K10.38463506
122PINK10.38325550
123CSNK1D0.37613342
124BRAF0.37308459
125TLK10.35592682
126CSNK1A10.35396970
127MAPK100.34597923
128NME10.34197595
129MAP3K60.33986298
130RIPK10.32510332
131MAP2K60.31782421
132MKNK20.30934380
133LIMK10.30602611
134CDK30.30586401
135BRSK10.29598304
136PRKCB0.29210512
137TNK20.27903247
138MAPK80.27209346
139CAMK2D0.26840517
140MAPK90.26158607

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.57189823
2Synaptic vesicle cycle_Homo sapiens_hsa047213.19454784
3Olfactory transduction_Homo sapiens_hsa047402.80556439
4Circadian entrainment_Homo sapiens_hsa047132.79646276
5Long-term potentiation_Homo sapiens_hsa047202.72168370
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.61085148
7GABAergic synapse_Homo sapiens_hsa047272.61084024
8Glutamatergic synapse_Homo sapiens_hsa047242.58024415
9Amphetamine addiction_Homo sapiens_hsa050312.55469097
10Morphine addiction_Homo sapiens_hsa050322.48979185
11Dopaminergic synapse_Homo sapiens_hsa047282.31564337
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.27735972
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.20276534
14Cholinergic synapse_Homo sapiens_hsa047252.03965383
15Insulin secretion_Homo sapiens_hsa049112.01705147
16Salivary secretion_Homo sapiens_hsa049701.99647057
17Cocaine addiction_Homo sapiens_hsa050301.92076425
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.88264475
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84807032
20Taste transduction_Homo sapiens_hsa047421.83204997
21Gastric acid secretion_Homo sapiens_hsa049711.75113076
22Serotonergic synapse_Homo sapiens_hsa047261.72874053
23Renin secretion_Homo sapiens_hsa049241.70041626
24Oxytocin signaling pathway_Homo sapiens_hsa049211.68994358
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.68799686
26Long-term depression_Homo sapiens_hsa047301.66373846
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.61815223
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.56802291
29Calcium signaling pathway_Homo sapiens_hsa040201.54192134
30GnRH signaling pathway_Homo sapiens_hsa049121.52838475
31Oxidative phosphorylation_Homo sapiens_hsa001901.52770643
32Butanoate metabolism_Homo sapiens_hsa006501.52487346
33Gap junction_Homo sapiens_hsa045401.46221110
34Axon guidance_Homo sapiens_hsa043601.38700442
35Parkinsons disease_Homo sapiens_hsa050121.31818344
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.30864275
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25941955
38Glioma_Homo sapiens_hsa052141.25691114
39Collecting duct acid secretion_Homo sapiens_hsa049661.25063124
40cAMP signaling pathway_Homo sapiens_hsa040241.24611731
41Estrogen signaling pathway_Homo sapiens_hsa049151.22553195
42Type II diabetes mellitus_Homo sapiens_hsa049301.17398722
43Ether lipid metabolism_Homo sapiens_hsa005651.16196812
44ErbB signaling pathway_Homo sapiens_hsa040121.14613538
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.13353830
46Melanogenesis_Homo sapiens_hsa049161.12411566
47Steroid biosynthesis_Homo sapiens_hsa001001.07186301
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05409671
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04490576
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04324543
51Fatty acid biosynthesis_Homo sapiens_hsa000610.99847466
52Linoleic acid metabolism_Homo sapiens_hsa005910.98777451
53Huntingtons disease_Homo sapiens_hsa050160.97802462
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.96505858
55cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94486472
56Selenocompound metabolism_Homo sapiens_hsa004500.94356655
57Vibrio cholerae infection_Homo sapiens_hsa051100.91991556
58Oocyte meiosis_Homo sapiens_hsa041140.91319467
59Cardiac muscle contraction_Homo sapiens_hsa042600.90845369
60Hedgehog signaling pathway_Homo sapiens_hsa043400.90355564
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.88675409
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.86715721
63Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84496583
64Vascular smooth muscle contraction_Homo sapiens_hsa042700.84119332
65Protein export_Homo sapiens_hsa030600.82246294
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81943718
67Regulation of autophagy_Homo sapiens_hsa041400.80445169
68Basal cell carcinoma_Homo sapiens_hsa052170.78772983
69Choline metabolism in cancer_Homo sapiens_hsa052310.76699782
70MAPK signaling pathway_Homo sapiens_hsa040100.76167064
71Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75945550
72Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75784869
73VEGF signaling pathway_Homo sapiens_hsa043700.75709227
74Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.75419824
75Pancreatic secretion_Homo sapiens_hsa049720.74469411
76Dorso-ventral axis formation_Homo sapiens_hsa043200.74401748
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.72783670
78Phototransduction_Homo sapiens_hsa047440.72749418
79Thyroid hormone synthesis_Homo sapiens_hsa049180.71684337
80Alcoholism_Homo sapiens_hsa050340.71658948
81Basal transcription factors_Homo sapiens_hsa030220.71635997
82Dilated cardiomyopathy_Homo sapiens_hsa054140.69076833
83Endometrial cancer_Homo sapiens_hsa052130.67541619
84RNA polymerase_Homo sapiens_hsa030200.66448591
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64579281
86Hippo signaling pathway_Homo sapiens_hsa043900.63773021
87Ras signaling pathway_Homo sapiens_hsa040140.62222810
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62050010
89Rap1 signaling pathway_Homo sapiens_hsa040150.60101089
90Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59162670
91Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58404589
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58312709
93Glucagon signaling pathway_Homo sapiens_hsa049220.57847543
94Non-small cell lung cancer_Homo sapiens_hsa052230.56062604
95Type I diabetes mellitus_Homo sapiens_hsa049400.54217321
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.53014278
97Prion diseases_Homo sapiens_hsa050200.52350500
98Wnt signaling pathway_Homo sapiens_hsa043100.52189241
99Circadian rhythm_Homo sapiens_hsa047100.51745640
100Endocytosis_Homo sapiens_hsa041440.51071875
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50688419
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.50454330
103Colorectal cancer_Homo sapiens_hsa052100.50022038
104mTOR signaling pathway_Homo sapiens_hsa041500.48702236
105Renal cell carcinoma_Homo sapiens_hsa052110.48659497
106Insulin signaling pathway_Homo sapiens_hsa049100.47404434
107Fanconi anemia pathway_Homo sapiens_hsa034600.45742627
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44046632
109Alzheimers disease_Homo sapiens_hsa050100.42862697
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41958026
111Fatty acid metabolism_Homo sapiens_hsa012120.41721809
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40540261
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39984535
114Prolactin signaling pathway_Homo sapiens_hsa049170.39388851
115Chemokine signaling pathway_Homo sapiens_hsa040620.38715393
116Inositol phosphate metabolism_Homo sapiens_hsa005620.36987794
117Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35556471
118RNA degradation_Homo sapiens_hsa030180.35548332
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35307899
120Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.34662404
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33289399
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31739591
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.30921996
124ABC transporters_Homo sapiens_hsa020100.29955146
125Nitrogen metabolism_Homo sapiens_hsa009100.29627200
126Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28618639
127Ovarian steroidogenesis_Homo sapiens_hsa049130.27645403
128Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.27257263
129Bile secretion_Homo sapiens_hsa049760.26387308
130beta-Alanine metabolism_Homo sapiens_hsa004100.25933331
131Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25519767
132Tryptophan metabolism_Homo sapiens_hsa003800.25458463
133Vitamin B6 metabolism_Homo sapiens_hsa007500.24508510
134Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.24245450
135African trypanosomiasis_Homo sapiens_hsa051430.23591395

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