

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 8.19675637 |
| 2 | definitive hemopoiesis (GO:0060216) | 7.55910448 |
| 3 | negative regulation of erythrocyte differentiation (GO:0045647) | 6.24679270 |
| 4 | viral transcription (GO:0019083) | 5.71907924 |
| 5 | translational termination (GO:0006415) | 5.43843752 |
| 6 | response to interferon-alpha (GO:0035455) | 5.33483637 |
| 7 | blood vessel maturation (GO:0001955) | 5.24980072 |
| 8 | platelet dense granule organization (GO:0060155) | 5.20638493 |
| 9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.13538013 |
| 10 | maturation of SSU-rRNA (GO:0030490) | 4.85614577 |
| 11 | response to interferon-beta (GO:0035456) | 4.76745281 |
| 12 | translational elongation (GO:0006414) | 4.64191410 |
| 13 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.39531629 |
| 14 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.37502588 |
| 15 | phospholipid scrambling (GO:0017121) | 4.32223503 |
| 16 | mature B cell differentiation involved in immune response (GO:0002313) | 4.31712794 |
| 17 | protein targeting to ER (GO:0045047) | 4.25460282 |
| 18 | ribosomal small subunit biogenesis (GO:0042274) | 4.24600733 |
| 19 | barbed-end actin filament capping (GO:0051016) | 4.23227158 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 4.22204283 |
| 21 | heparin metabolic process (GO:0030202) | 4.09488333 |
| 22 | heparin biosynthetic process (GO:0030210) | 4.09488333 |
| 23 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.04619998 |
| 24 | protein localization to endoplasmic reticulum (GO:0070972) | 3.97591996 |
| 25 | viral life cycle (GO:0019058) | 3.97236306 |
| 26 | endosome to melanosome transport (GO:0035646) | 3.96990700 |
| 27 | endosome to pigment granule transport (GO:0043485) | 3.96990700 |
| 28 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.93245286 |
| 29 | cellular protein complex disassembly (GO:0043624) | 3.86958299 |
| 30 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.78338264 |
| 31 | semaphorin-plexin signaling pathway (GO:0071526) | 3.68151278 |
| 32 | positive regulation of extracellular matrix organization (GO:1903055) | 3.64015108 |
| 33 | phagocytosis, recognition (GO:0006910) | 3.58346607 |
| 34 | COPI coating of Golgi vesicle (GO:0048205) | 3.57393238 |
| 35 | Golgi transport vesicle coating (GO:0048200) | 3.57393238 |
| 36 | desmosome organization (GO:0002934) | 3.52321815 |
| 37 | negative regulation of viral entry into host cell (GO:0046597) | 3.49464200 |
| 38 | nodal signaling pathway (GO:0038092) | 3.48436724 |
| 39 | protein retention in ER lumen (GO:0006621) | 3.48053085 |
| 40 | basement membrane organization (GO:0071711) | 3.45698371 |
| 41 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.43836600 |
| 42 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.43836600 |
| 43 | protein localization to endosome (GO:0036010) | 3.40129916 |
| 44 | translational initiation (GO:0006413) | 3.38014188 |
| 45 | regulation of extracellular matrix disassembly (GO:0010715) | 3.38013534 |
| 46 | protein complex disassembly (GO:0043241) | 3.37015564 |
| 47 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.34951580 |
| 48 | regulation of extracellular matrix organization (GO:1903053) | 3.34061481 |
| 49 | regulation of natural killer cell differentiation (GO:0032823) | 3.33322250 |
| 50 | regulation of cholesterol biosynthetic process (GO:0045540) | 3.27082221 |
| 51 | megakaryocyte development (GO:0035855) | 3.23509611 |
| 52 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.21804234 |
| 53 | Peyers patch development (GO:0048541) | 3.21804234 |
| 54 | facial nerve structural organization (GO:0021612) | 3.21626239 |
| 55 | secretory granule organization (GO:0033363) | 3.20387923 |
| 56 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.17128192 |
| 57 | regulation of early endosome to late endosome transport (GO:2000641) | 3.05390506 |
| 58 | regulation of cholesterol homeostasis (GO:2000188) | 3.04711837 |
| 59 | macromolecular complex disassembly (GO:0032984) | 3.03446282 |
| 60 | adhesion of symbiont to host (GO:0044406) | 3.00383941 |
| 61 | protein targeting to membrane (GO:0006612) | 3.00051532 |
| 62 | positive regulation of respiratory burst (GO:0060267) | 2.99415997 |
| 63 | regulation of apoptotic cell clearance (GO:2000425) | 2.97692958 |
| 64 | lymph node development (GO:0048535) | 2.96475235 |
| 65 | low-density lipoprotein particle clearance (GO:0034383) | 2.94636763 |
| 66 | glycosphingolipid catabolic process (GO:0046479) | 2.93717627 |
| 67 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.92723584 |
| 68 | purine-containing compound salvage (GO:0043101) | 2.92361193 |
| 69 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 2.90939283 |
| 70 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.87781766 |
| 71 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.87351391 |
| 72 | regulation of macrophage chemotaxis (GO:0010758) | 2.86975337 |
| 73 | cell volume homeostasis (GO:0006884) | 2.86296044 |
| 74 | regulation of viral entry into host cell (GO:0046596) | 2.85400473 |
| 75 | endothelial cell chemotaxis (GO:0035767) | 2.83294566 |
| 76 | epithelial cell-cell adhesion (GO:0090136) | 2.82468891 |
| 77 | mature B cell differentiation (GO:0002335) | 2.82209905 |
| 78 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.81813093 |
| 79 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.81112737 |
| 80 | protein heterotrimerization (GO:0070208) | 2.78950885 |
| 81 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.78950657 |
| 82 | negative regulation of stress fiber assembly (GO:0051497) | 2.78863084 |
| 83 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.78301821 |
| 84 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.77506022 |
| 85 | adenosine receptor signaling pathway (GO:0001973) | 2.76944980 |
| 86 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.74752409 |
| 87 | regulation of integrin activation (GO:0033623) | 2.72515132 |
| 88 | chondroitin sulfate catabolic process (GO:0030207) | 2.72311694 |
| 89 | skin morphogenesis (GO:0043589) | 2.72099982 |
| 90 | response to thyroid hormone (GO:0097066) | 2.71893834 |
| 91 | cell-cell junction maintenance (GO:0045217) | 2.70718349 |
| 92 | embryonic hemopoiesis (GO:0035162) | 2.69809561 |
| 93 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.69361043 |
| 94 | cell-substrate junction assembly (GO:0007044) | 2.69354972 |
| 95 | glycolipid catabolic process (GO:0019377) | 2.68374400 |
| 96 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 2.68063633 |
| 97 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.67324693 |
| 98 | negative regulation of viral genome replication (GO:0045071) | 2.66704583 |
| 99 | execution phase of apoptosis (GO:0097194) | 2.66290921 |
| 100 | NIK/NF-kappaB signaling (GO:0038061) | 2.65401057 |
| 101 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.65370905 |
| 102 | apoptotic cell clearance (GO:0043277) | 2.65252073 |
| 103 | virion attachment to host cell (GO:0019062) | 2.63024474 |
| 104 | adhesion of symbiont to host cell (GO:0044650) | 2.63024474 |
| 105 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.62479146 |
| 106 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2.61709421 |
| 107 | positive regulation of pseudopodium assembly (GO:0031274) | 2.60353289 |
| 108 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.59916758 |
| 109 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.59608192 |
| 110 | UV protection (GO:0009650) | 2.59577806 |
| 111 | erythrocyte maturation (GO:0043249) | 2.58833447 |
| 112 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.58168329 |
| 113 | stress fiber assembly (GO:0043149) | 2.58152361 |
| 114 | angiogenesis involved in wound healing (GO:0060055) | 2.56667860 |
| 115 | mRNA catabolic process (GO:0006402) | 2.56258739 |
| 116 | hyaluronan catabolic process (GO:0030214) | 2.55820441 |
| 117 | positive regulation of receptor recycling (GO:0001921) | 2.55668983 |
| 118 | renal filtration (GO:0097205) | 2.55352522 |
| 119 | negative regulation of granulocyte differentiation (GO:0030853) | 2.53340085 |
| 120 | mRNA transcription (GO:0009299) | 2.52517469 |
| 121 | positive regulation of odontogenesis (GO:0042482) | 2.52303848 |
| 122 | glial cell migration (GO:0008347) | 2.52043225 |
| 123 | oligosaccharide catabolic process (GO:0009313) | 2.49963182 |
| 124 | regulation of cholesterol esterification (GO:0010872) | 2.49716402 |
| 125 | atrioventricular valve morphogenesis (GO:0003181) | 2.49399934 |
| 126 | activation of Rac GTPase activity (GO:0032863) | 2.48950517 |
| 127 | positive regulation of osteoblast proliferation (GO:0033690) | 2.47436461 |
| 128 | negative regulation of protein autophosphorylation (GO:0031953) | 2.45845566 |
| 129 | galactose catabolic process (GO:0019388) | 2.45701989 |
| 130 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.45419843 |
| 131 | keratan sulfate catabolic process (GO:0042340) | 2.45357417 |
| 132 | regulation of cholesterol storage (GO:0010885) | 2.45072431 |
| 133 | smooth muscle tissue development (GO:0048745) | 2.44848651 |
| 134 | phagocytosis, engulfment (GO:0006911) | 2.44468180 |
| 135 | regulation of cholesterol metabolic process (GO:0090181) | 2.43719886 |
| 136 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 2.43666113 |
| 137 | positive regulation of triglyceride lipase activity (GO:0061365) | 2.43058942 |
| 138 | positive regulation of lipoprotein lipase activity (GO:0051006) | 2.43058942 |
| 139 | positive regulation of DNA biosynthetic process (GO:2000573) | 2.42833329 |
| 140 | amino sugar catabolic process (GO:0046348) | 2.41948444 |
| 141 | apoptotic process involved in morphogenesis (GO:0060561) | 2.40898111 |
| 142 | embryonic process involved in female pregnancy (GO:0060136) | 2.40693704 |
| 143 | negative regulation of bone mineralization (GO:0030502) | 2.40414955 |
| 144 | membrane raft organization (GO:0031579) | 2.40355862 |
| 145 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 2.40332807 |
| 146 | negative regulation of response to reactive oxygen species (GO:1901032) | 2.39759731 |
| 147 | negative regulation of biomineral tissue development (GO:0070168) | 2.39547774 |
| 148 | hemidesmosome assembly (GO:0031581) | 2.39422243 |
| 149 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 2.39370041 |
| 150 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.39004321 |
| 151 | activation of MAPKKK activity (GO:0000185) | 2.38631290 |
| 152 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.38576185 |
| 153 | valine metabolic process (GO:0006573) | 2.38450234 |
| 154 | gland morphogenesis (GO:0022612) | 2.38126990 |
| 155 | regulation of superoxide anion generation (GO:0032928) | 2.38063159 |
| 156 | GDP-mannose metabolic process (GO:0019673) | 2.37840160 |
| 157 | collagen fibril organization (GO:0030199) | 2.37750496 |
| 158 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.37452766 |
| 159 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.37452766 |
| 160 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.37265317 |
| 161 | Rho protein signal transduction (GO:0007266) | 2.36862252 |
| 162 | mannose metabolic process (GO:0006013) | 2.36849756 |
| 163 | cytokine production involved in immune response (GO:0002367) | 2.36270764 |
| 164 | adherens junction assembly (GO:0034333) | 2.36150512 |
| 165 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.35221999 |
| 166 | platelet aggregation (GO:0070527) | 2.34692535 |
| 167 | lipopolysaccharide metabolic process (GO:0008653) | 2.32913299 |
| 168 | pinocytosis (GO:0006907) | 2.32338039 |
| 169 | fibroblast migration (GO:0010761) | 2.32253458 |
| 170 | response to type I interferon (GO:0034340) | 2.31354866 |
| 171 | regulation of gamma-delta T cell activation (GO:0046643) | 2.30998118 |
| 172 | interleukin-1-mediated signaling pathway (GO:0070498) | 2.30879154 |
| 173 | chondroitin sulfate biosynthetic process (GO:0030206) | 2.30665659 |
| 174 | embryo implantation (GO:0007566) | 2.29973296 |
| 175 | proline biosynthetic process (GO:0006561) | 2.29814228 |
| 176 | cellular response to cadmium ion (GO:0071276) | 2.29263255 |
| 177 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.28472974 |
| 178 | endothelial cell morphogenesis (GO:0001886) | 2.26980243 |
| 179 | regulation of pseudopodium assembly (GO:0031272) | 2.26718562 |
| 180 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.26037649 |
| 181 | surfactant homeostasis (GO:0043129) | 2.25802882 |
| 182 | focal adhesion assembly (GO:0048041) | 2.24768475 |
| 183 | cell-substrate adherens junction assembly (GO:0007045) | 2.24768475 |
| 184 | plasma lipoprotein particle clearance (GO:0034381) | 2.23885596 |
| 185 | complement activation, classical pathway (GO:0006958) | 2.23570711 |
| 186 | endothelium development (GO:0003158) | 2.22506448 |
| 187 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.21879566 |
| 188 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 2.21645889 |
| 189 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.20788383 |
| 190 | peptide catabolic process (GO:0043171) | 2.20444815 |
| 191 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.18180167 |
| 192 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.16920209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.91415765 |
| 2 | SCL_19346495_ChIP-Seq_HPC-7_Human | 4.60218803 |
| 3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.03575557 |
| 4 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.81104744 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.65473759 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.63425343 |
| 7 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.59782138 |
| 8 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.50072460 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.40491367 |
| 10 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.38028735 |
| 11 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.37906296 |
| 12 | MYC_22102868_ChIP-Seq_BL_Human | 2.34942764 |
| 13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.15963332 |
| 14 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.14170774 |
| 15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.12781340 |
| 16 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.11629449 |
| 17 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.08162173 |
| 18 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.06086784 |
| 19 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.03467053 |
| 20 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99609257 |
| 21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.98133827 |
| 22 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.96611766 |
| 23 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.93962260 |
| 24 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.91418670 |
| 25 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.88450511 |
| 26 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.87361430 |
| 27 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.84563403 |
| 28 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.78396252 |
| 29 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.74556200 |
| 30 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.73411832 |
| 31 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.73371463 |
| 32 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.73054106 |
| 33 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.68408488 |
| 34 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.68341993 |
| 35 | KDM2B_26808549_Chip-Seq_K562_Human | 1.67453874 |
| 36 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.66440271 |
| 37 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.66427545 |
| 38 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.63298880 |
| 39 | GATA1_22025678_ChIP-Seq_K562_Human | 1.62895419 |
| 40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.62547402 |
| 41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.62320278 |
| 42 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.61751103 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60361936 |
| 44 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.59667071 |
| 45 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.59288371 |
| 46 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.58915155 |
| 47 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.57043562 |
| 48 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.56454364 |
| 49 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.53961263 |
| 50 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.53244672 |
| 51 | * MAF_26560356_Chip-Seq_TH1_Human | 1.52861878 |
| 52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.52421460 |
| 53 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.52171739 |
| 54 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.51785192 |
| 55 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.51119073 |
| 56 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.51095945 |
| 57 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.49208003 |
| 58 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.47453704 |
| 59 | * P68_20966046_ChIP-Seq_HELA_Human | 1.46539779 |
| 60 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.46225465 |
| 61 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.44824046 |
| 62 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.44116388 |
| 63 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.42512323 |
| 64 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.41601109 |
| 65 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.41408349 |
| 66 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.39411208 |
| 67 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39108124 |
| 68 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.38966592 |
| 69 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.36726611 |
| 70 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.35691256 |
| 71 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.34853225 |
| 72 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.33910826 |
| 73 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.33896884 |
| 74 | GATA1_19941826_ChIP-Seq_K562_Human | 1.32970337 |
| 75 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.32257658 |
| 76 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.32161492 |
| 77 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.32006735 |
| 78 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.31226418 |
| 79 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.30782896 |
| 80 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.30574340 |
| 81 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.30369224 |
| 82 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.30182878 |
| 83 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.29674610 |
| 84 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.29449956 |
| 85 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.28116325 |
| 86 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.27633098 |
| 87 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.27451593 |
| 88 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.26832824 |
| 89 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.26291636 |
| 90 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.25705957 |
| 91 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.23654590 |
| 92 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.23449774 |
| 93 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.23352808 |
| 94 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.21301386 |
| 95 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.21291261 |
| 96 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.20338392 |
| 97 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.19925749 |
| 98 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.19504791 |
| 99 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.18575095 |
| 100 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.18575095 |
| 101 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.18450706 |
| 102 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.18410414 |
| 103 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.16677158 |
| 104 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.15852464 |
| 105 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.15365243 |
| 106 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.14835410 |
| 107 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.13947063 |
| 108 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.13403979 |
| 109 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.12954509 |
| 110 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.12103218 |
| 111 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.12084519 |
| 112 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.12039722 |
| 113 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.11817198 |
| 114 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.11462926 |
| 115 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.11209712 |
| 116 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.09337481 |
| 117 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.08612736 |
| 118 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.08593601 |
| 119 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.08237791 |
| 120 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07447025 |
| 121 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.07443676 |
| 122 | * CTCF_21964334_Chip-Seq_Bcells_Human | 1.06905820 |
| 123 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.06669743 |
| 124 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.06652751 |
| 125 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06433450 |
| 126 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.04904654 |
| 127 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.03358917 |
| 128 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02407821 |
| 129 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.02392493 |
| 130 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.02080864 |
| 131 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.01845515 |
| 132 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.01800426 |
| 133 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.01458656 |
| 134 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.01301004 |
| 135 | MYB_26560356_Chip-Seq_TH1_Human | 1.01185996 |
| 136 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00834607 |
| 137 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.99802637 |
| 138 | GATA2_19941826_ChIP-Seq_K562_Human | 0.99701399 |
| 139 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.99211200 |
| 140 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.99087835 |
| 141 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.98927897 |
| 142 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.98337883 |
| 143 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.97587514 |
| 144 | SPI1_23127762_ChIP-Seq_K562_Human | 0.97483033 |
| 145 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.96773509 |
| 146 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.96174513 |
| 147 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.96174513 |
| 148 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.95142313 |
| 149 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.95105879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009840_abnormal_foam_cell | 3.87141798 |
| 2 | MP0003279_aneurysm | 3.03762151 |
| 3 | MP0008438_abnormal_cutaneous_collagen | 2.95031138 |
| 4 | MP0010368_abnormal_lymphatic_system | 2.85912547 |
| 5 | MP0003453_abnormal_keratinocyte_physiol | 2.49640832 |
| 6 | MP0004510_myositis | 2.49462954 |
| 7 | MP0009278_abnormal_bone_marrow | 2.44671226 |
| 8 | MP0010234_abnormal_vibrissa_follicle | 2.37817998 |
| 9 | MP0004808_abnormal_hematopoietic_stem | 2.37108964 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.36621050 |
| 11 | MP0003191_abnormal_cellular_cholesterol | 2.22681630 |
| 12 | MP0001958_emphysema | 2.21852078 |
| 13 | MP0006054_spinal_hemorrhage | 2.12307571 |
| 14 | MP0002396_abnormal_hematopoietic_system | 2.06889612 |
| 15 | MP0000465_gastrointestinal_hemorrhage | 2.06560727 |
| 16 | MP0003075_altered_response_to | 2.05917769 |
| 17 | MP0003724_increased_susceptibility_to | 2.05887263 |
| 18 | MP0005397_hematopoietic_system_phenotyp | 2.03378703 |
| 19 | MP0001545_abnormal_hematopoietic_system | 2.03378703 |
| 20 | MP0005409_darkened_coat_color | 2.00718541 |
| 21 | MP0002254_reproductive_system_inflammat | 2.00513099 |
| 22 | MP0003329_amyloid_beta_deposits | 1.97617012 |
| 23 | MP0002139_abnormal_hepatobiliary_system | 1.96000987 |
| 24 | MP0002933_joint_inflammation | 1.93304833 |
| 25 | MP0005503_abnormal_tendon_morphology | 1.90360713 |
| 26 | MP0005464_abnormal_platelet_physiology | 1.90193997 |
| 27 | MP0004084_abnormal_cardiac_muscle | 1.90120002 |
| 28 | MP0005257_abnormal_intraocular_pressure | 1.89940891 |
| 29 | MP0003566_abnormal_cell_adhesion | 1.87227630 |
| 30 | MP0005275_abnormal_skin_tensile | 1.82793860 |
| 31 | MP0004272_abnormal_basement_membrane | 1.79005028 |
| 32 | MP0003172_abnormal_lysosome_physiology | 1.78758870 |
| 33 | MP0000604_amyloidosis | 1.78644865 |
| 34 | MP0003828_pulmonary_edema | 1.76325990 |
| 35 | MP0005360_urolithiasis | 1.74315898 |
| 36 | MP0003705_abnormal_hypodermis_morpholog | 1.73466581 |
| 37 | MP0004858_abnormal_nervous_system | 1.69080863 |
| 38 | MP0000685_abnormal_immune_system | 1.68810842 |
| 39 | MP0008260_abnormal_autophagy | 1.61455995 |
| 40 | MP0000678_abnormal_parathyroid_gland | 1.59288675 |
| 41 | MP0000858_altered_metastatic_potential | 1.59075091 |
| 42 | MP0005023_abnormal_wound_healing | 1.58764416 |
| 43 | MP0003303_peritoneal_inflammation | 1.58033106 |
| 44 | MP0000767_abnormal_smooth_muscle | 1.57955362 |
| 45 | MP0001851_eye_inflammation | 1.57640374 |
| 46 | MP0005167_abnormal_blood-brain_barrier | 1.56839990 |
| 47 | MP0005451_abnormal_body_composition | 1.55590179 |
| 48 | MP0001879_abnormal_lymphatic_vessel | 1.54705274 |
| 49 | MP0003690_abnormal_glial_cell | 1.54518876 |
| 50 | MP0005365_abnormal_bile_salt | 1.49180209 |
| 51 | MP0003283_abnormal_digestive_organ | 1.41816772 |
| 52 | MP0001873_stomach_inflammation | 1.40981893 |
| 53 | MP0000751_myopathy | 1.39964562 |
| 54 | MP0000343_altered_response_to | 1.38776513 |
| 55 | MP0002796_impaired_skin_barrier | 1.38035519 |
| 56 | MP0005076_abnormal_cell_differentiation | 1.36244205 |
| 57 | MP0003634_abnormal_glial_cell | 1.35700206 |
| 58 | MP0005166_decreased_susceptibility_to | 1.34869898 |
| 59 | MP0001835_abnormal_antigen_presentation | 1.32971963 |
| 60 | MP0002249_abnormal_larynx_morphology | 1.30538925 |
| 61 | MP0005670_abnormal_white_adipose | 1.28271517 |
| 62 | MP0002998_abnormal_bone_remodeling | 1.27598461 |
| 63 | MP0005058_abnormal_lysosome_morphology | 1.26015560 |
| 64 | MP0000003_abnormal_adipose_tissue | 1.24051944 |
| 65 | MP0003941_abnormal_skin_development | 1.23296184 |
| 66 | MP0000749_muscle_degeneration | 1.22906922 |
| 67 | MP0000920_abnormal_myelination | 1.22176690 |
| 68 | MP0003300_gastrointestinal_ulcer | 1.20277979 |
| 69 | MP0004036_abnormal_muscle_relaxation | 1.18198341 |
| 70 | MP0005595_abnormal_vascular_smooth | 1.17986737 |
| 71 | MP0001216_abnormal_epidermal_layer | 1.17364378 |
| 72 | MP0002060_abnormal_skin_morphology | 1.17134851 |
| 73 | MP0002896_abnormal_bone_mineralization | 1.15990569 |
| 74 | MP0005508_abnormal_skeleton_morphology | 1.13606144 |
| 75 | MP0001849_ear_inflammation | 1.13534531 |
| 76 | MP0003448_altered_tumor_morphology | 1.12522895 |
| 77 | MP0000467_abnormal_esophagus_morphology | 1.11570087 |
| 78 | MP0005025_abnormal_response_to | 1.11390579 |
| 79 | MP0001533_abnormal_skeleton_physiology | 1.11173051 |
| 80 | MP0009785_altered_susceptibility_to | 1.10965310 |
| 81 | MP0005623_abnormal_meninges_morphology | 1.09990333 |
| 82 | MP0005375_adipose_tissue_phenotype | 1.09478293 |
| 83 | MP0001853_heart_inflammation | 1.09281795 |
| 84 | MP0005501_abnormal_skin_physiology | 1.08896502 |
| 85 | MP0003183_abnormal_peptide_metabolism | 1.08865356 |
| 86 | MP0005390_skeleton_phenotype | 1.08834162 |
| 87 | MP0002128_abnormal_blood_circulation | 1.08565193 |
| 88 | MP0004185_abnormal_adipocyte_glucose | 1.06814809 |
| 89 | MP0001915_intracranial_hemorrhage | 1.06379520 |
| 90 | MP0002419_abnormal_innate_immunity | 1.04985549 |
| 91 | MP0003806_abnormal_nucleotide_metabolis | 1.04450198 |
| 92 | MP0000689_abnormal_spleen_morphology | 1.03588157 |
| 93 | MP0002452_abnormal_antigen_presenting | 1.02945557 |
| 94 | MP0003943_abnormal_hepatobiliary_system | 1.02667706 |
| 95 | MP0002234_abnormal_pharynx_morphology | 1.02058925 |
| 96 | MP0000762_abnormal_tongue_morphology | 1.01321161 |
| 97 | MP0003878_abnormal_ear_physiology | 1.01094530 |
| 98 | MP0005377_hearing/vestibular/ear_phenot | 1.01094530 |
| 99 | MP0010030_abnormal_orbit_morphology | 1.01014238 |
| 100 | MP0003436_decreased_susceptibility_to | 1.00938166 |
| 101 | MP0000750_abnormal_muscle_regeneration | 1.00935281 |
| 102 | MP0010630_abnormal_cardiac_muscle | 1.00193933 |
| 103 | MP0003795_abnormal_bone_structure | 0.98598039 |
| 104 | MP0000681_abnormal_thyroid_gland | 0.96076213 |
| 105 | MP0010155_abnormal_intestine_physiology | 0.95465461 |
| 106 | MP0004947_skin_inflammation | 0.94794137 |
| 107 | MP0005174_abnormal_tail_pigmentation | 0.93258770 |
| 108 | MP0002113_abnormal_skeleton_development | 0.92843190 |
| 109 | MP0002877_abnormal_melanocyte_morpholog | 0.92220689 |
| 110 | MP0002138_abnormal_hepatobiliary_system | 0.91427683 |
| 111 | MP0003091_abnormal_cell_migration | 0.91005650 |
| 112 | MP0000747_muscle_weakness | 0.90982867 |
| 113 | MP0002420_abnormal_adaptive_immunity | 0.89946391 |
| 114 | MP0001614_abnormal_blood_vessel | 0.89820275 |
| 115 | MP0001819_abnormal_immune_cell | 0.89796848 |
| 116 | MP0002398_abnormal_bone_marrow | 0.88936987 |
| 117 | MP0002723_abnormal_immune_serum | 0.88601728 |
| 118 | MP0002722_abnormal_immune_system | 0.88330517 |
| 119 | MP0010352_gastrointestinal_tract_polyps | 0.88143592 |
| 120 | MP0009384_cardiac_valve_regurgitation | 0.87823516 |
| 121 | MP0002282_abnormal_trachea_morphology | 0.87405297 |
| 122 | MP0009780_abnormal_chondrocyte_physiolo | 0.86940118 |
| 123 | MP0005330_cardiomyopathy | 0.86801687 |
| 124 | MP0000579_abnormal_nail_morphology | 0.86529647 |
| 125 | MP0000013_abnormal_adipose_tissue | 0.86296602 |
| 126 | MP0000163_abnormal_cartilage_morphology | 0.84892996 |
| 127 | MP0005164_abnormal_response_to | 0.84866899 |
| 128 | MP0000490_abnormal_crypts_of | 0.84728428 |
| 129 | MP0002089_abnormal_postnatal_growth/wei | 0.84365643 |
| 130 | MP0005165_increased_susceptibility_to | 0.84309021 |
| 131 | MP0002148_abnormal_hypersensitivity_rea | 0.84293427 |
| 132 | MP0006082_CNS_inflammation | 0.83178795 |
| 133 | MP0005666_abnormal_adipose_tissue | 0.82967233 |
| 134 | MP0000733_abnormal_muscle_development | 0.81937898 |
| 135 | MP0004130_abnormal_muscle_cell | 0.80547606 |
| 136 | MP0008004_abnormal_stomach_pH | 0.80231654 |
| 137 | MP0003950_abnormal_plasma_membrane | 0.79501996 |
| 138 | MP0002429_abnormal_blood_cell | 0.79317501 |
| 139 | MP0008775_abnormal_heart_ventricle | 0.79234435 |
| 140 | MP0001544_abnormal_cardiovascular_syste | 0.78404066 |
| 141 | MP0005385_cardiovascular_system_phenoty | 0.78404066 |
| 142 | MP0000249_abnormal_blood_vessel | 0.78219685 |
| 143 | MP0000716_abnormal_immune_system | 0.78152240 |
| 144 | MP0009333_abnormal_splenocyte_physiolog | 0.77664473 |
| 145 | MP0001800_abnormal_humoral_immune | 0.77352015 |
| 146 | MP0004233_abnormal_muscle_weight | 0.77344128 |
| 147 | MP0001542_abnormal_bone_strength | 0.76830933 |
| 148 | MP0006138_congestive_heart_failure | 0.73517496 |
| 149 | MP0008874_decreased_physiological_sensi | 0.69399182 |
| 150 | MP0002098_abnormal_vibrissa_morphology | 0.68647993 |
| 151 | MP0009931_abnormal_skin_appearance | 0.67872955 |
| 152 | MP0000566_synostosis | 0.66874657 |
| 153 | MP0004019_abnormal_vitamin_homeostasis | 0.65978655 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protrusio acetabuli (HP:0003179) | 5.36489273 |
| 2 | Thrombocytosis (HP:0001894) | 4.54955087 |
| 3 | Systemic lupus erythematosus (HP:0002725) | 4.35174060 |
| 4 | Abnormality of glycolipid metabolism (HP:0010969) | 4.20793544 |
| 5 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.20793544 |
| 6 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.20793544 |
| 7 | Premature rupture of membranes (HP:0001788) | 3.93530697 |
| 8 | Prolonged bleeding time (HP:0003010) | 3.71948612 |
| 9 | Cervical subluxation (HP:0003308) | 3.57007626 |
| 10 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.50919915 |
| 11 | Nuclear cataract (HP:0100018) | 3.50360531 |
| 12 | Dysostosis multiplex (HP:0000943) | 3.44005968 |
| 13 | Ankle contracture (HP:0006466) | 3.39081958 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.35696683 |
| 15 | Neurofibrillary tangles (HP:0002185) | 3.32136428 |
| 16 | Axonal loss (HP:0003447) | 3.25962784 |
| 17 | Complement deficiency (HP:0004431) | 3.23547032 |
| 18 | Abnormality of complement system (HP:0005339) | 3.20975688 |
| 19 | Aortic aneurysm (HP:0004942) | 3.19451109 |
| 20 | Increased connective tissue (HP:0009025) | 3.17927713 |
| 21 | Aortic dissection (HP:0002647) | 3.13331335 |
| 22 | Beaking of vertebral bodies (HP:0004568) | 3.12182078 |
| 23 | Broad metatarsal (HP:0001783) | 3.10200385 |
| 24 | Impaired platelet aggregation (HP:0003540) | 3.03193172 |
| 25 | Abnormal platelet function (HP:0011869) | 3.03193172 |
| 26 | Glomerulonephritis (HP:0000099) | 2.95095079 |
| 27 | Radial bowing (HP:0002986) | 2.92079760 |
| 28 | Spinal rigidity (HP:0003306) | 2.90354383 |
| 29 | Hyperacusis (HP:0010780) | 2.87182519 |
| 30 | Nonprogressive disorder (HP:0003680) | 2.86985164 |
| 31 | Deep venous thrombosis (HP:0002625) | 2.83986831 |
| 32 | Biconcave vertebral bodies (HP:0004586) | 2.81216811 |
| 33 | Type 1 muscle fiber predominance (HP:0003803) | 2.78515520 |
| 34 | Atrophic scars (HP:0001075) | 2.77804560 |
| 35 | Neonatal short-limb short stature (HP:0008921) | 2.75680974 |
| 36 | Vertebral compression fractures (HP:0002953) | 2.74508450 |
| 37 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.73693990 |
| 38 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.73693990 |
| 39 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.73693990 |
| 40 | Cerebral inclusion bodies (HP:0100314) | 2.72793876 |
| 41 | Mucopolysacchariduria (HP:0008155) | 2.72623887 |
| 42 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.72623887 |
| 43 | Achilles tendon contracture (HP:0001771) | 2.71266828 |
| 44 | Reticulocytopenia (HP:0001896) | 2.61120187 |
| 45 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.59542899 |
| 46 | Loss of speech (HP:0002371) | 2.59066163 |
| 47 | Abnormality of the Achilles tendon (HP:0005109) | 2.58174372 |
| 48 | Short nail (HP:0001799) | 2.56601979 |
| 49 | Abnormality of the nasal mucosa (HP:0000433) | 2.55684017 |
| 50 | Epistaxis (HP:0000421) | 2.53981647 |
| 51 | Upper limb amyotrophy (HP:0009129) | 2.53587551 |
| 52 | Distal upper limb amyotrophy (HP:0007149) | 2.53587551 |
| 53 | Type 2 muscle fiber atrophy (HP:0003554) | 2.51004580 |
| 54 | Muscle fiber atrophy (HP:0100295) | 2.50330217 |
| 55 | Distal lower limb amyotrophy (HP:0008944) | 2.49252824 |
| 56 | Peritonitis (HP:0002586) | 2.46925594 |
| 57 | Increased cerebral lipofuscin (HP:0011813) | 2.45521643 |
| 58 | Follicular hyperkeratosis (HP:0007502) | 2.44320963 |
| 59 | Hemorrhage of the eye (HP:0011885) | 2.43814622 |
| 60 | Asymmetric septal hypertrophy (HP:0001670) | 2.43059178 |
| 61 | Fragile skin (HP:0001030) | 2.42586365 |
| 62 | Menorrhagia (HP:0000132) | 2.40907401 |
| 63 | Abnormality of skull ossification (HP:0002703) | 2.40057378 |
| 64 | Soft skin (HP:0000977) | 2.38668093 |
| 65 | Increased variability in muscle fiber diameter (HP:0003557) | 2.36237072 |
| 66 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.33486223 |
| 67 | Joint stiffness (HP:0001387) | 2.31741969 |
| 68 | Bruising susceptibility (HP:0000978) | 2.30163931 |
| 69 | J-shaped sella turcica (HP:0002680) | 2.29812200 |
| 70 | Cerebral aneurysm (HP:0004944) | 2.27684739 |
| 71 | Diaphragmatic weakness (HP:0009113) | 2.26239692 |
| 72 | Abnormality of the acetabulum (HP:0003170) | 2.26208712 |
| 73 | Vacuolated lymphocytes (HP:0001922) | 2.24909753 |
| 74 | Obstructive sleep apnea (HP:0002870) | 2.24712175 |
| 75 | Bowing of the arm (HP:0006488) | 2.22960483 |
| 76 | Bowed forearm bones (HP:0003956) | 2.22960483 |
| 77 | Entropion (HP:0000621) | 2.22861921 |
| 78 | Xanthomatosis (HP:0000991) | 2.21568886 |
| 79 | Stridor (HP:0010307) | 2.19651999 |
| 80 | Ulnar bowing (HP:0003031) | 2.16738249 |
| 81 | Ovoid vertebral bodies (HP:0003300) | 2.16365552 |
| 82 | Hematochezia (HP:0002573) | 2.14492065 |
| 83 | Decreased skull ossification (HP:0004331) | 2.12930879 |
| 84 | Spontaneous hematomas (HP:0007420) | 2.08071679 |
| 85 | Interstitial pulmonary disease (HP:0006530) | 2.07889389 |
| 86 | Hyperparathyroidism (HP:0000843) | 2.06592588 |
| 87 | Flat acetabular roof (HP:0003180) | 2.06541801 |
| 88 | Generalized amyotrophy (HP:0003700) | 2.06004768 |
| 89 | Aplastic anemia (HP:0001915) | 2.05107259 |
| 90 | Distal lower limb muscle weakness (HP:0009053) | 2.04977461 |
| 91 | Fatigue (HP:0012378) | 2.03376471 |
| 92 | Nephritis (HP:0000123) | 2.02727248 |
| 93 | Aneurysm (HP:0002617) | 2.02314898 |
| 94 | Myocardial infarction (HP:0001658) | 2.01983425 |
| 95 | Insomnia (HP:0100785) | 2.01890593 |
| 96 | Striae distensae (HP:0001065) | 2.01881018 |
| 97 | Weak cry (HP:0001612) | 2.00953498 |
| 98 | Spinal cord lesions (HP:0100561) | 2.00893779 |
| 99 | Syringomyelia (HP:0003396) | 2.00893779 |
| 100 | Bulbar palsy (HP:0001283) | 2.00185493 |
| 101 | Polygenic inheritance (HP:0010982) | 1.99085560 |
| 102 | Supranuclear gaze palsy (HP:0000605) | 1.98924723 |
| 103 | Lumbar hyperlordosis (HP:0002938) | 1.98885556 |
| 104 | Petechiae (HP:0000967) | 1.98693222 |
| 105 | Difficulty climbing stairs (HP:0003551) | 1.98233995 |
| 106 | Thin bony cortex (HP:0002753) | 1.97853908 |
| 107 | Broad face (HP:0000283) | 1.97792176 |
| 108 | Coxa vara (HP:0002812) | 1.97498855 |
| 109 | Abnormality of the neuromuscular junction (HP:0003398) | 1.95565453 |
| 110 | Fatigable weakness (HP:0003473) | 1.95565453 |
| 111 | Dilatation of the ascending aorta (HP:0005111) | 1.94477944 |
| 112 | Ulnar deviation of the wrist (HP:0003049) | 1.94460172 |
| 113 | Lipoatrophy (HP:0100578) | 1.93788954 |
| 114 | Vascular tortuosity (HP:0004948) | 1.93724566 |
| 115 | Wormian bones (HP:0002645) | 1.93526196 |
| 116 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.92585304 |
| 117 | Natal tooth (HP:0000695) | 1.91857659 |
| 118 | Mitral valve prolapse (HP:0001634) | 1.91086675 |
| 119 | Thoracic kyphosis (HP:0002942) | 1.90400328 |
| 120 | Amyloidosis (HP:0011034) | 1.90131178 |
| 121 | Neonatal death (HP:0003811) | 1.90002910 |
| 122 | Osteolytic defects of the hand bones (HP:0009699) | 1.89740224 |
| 123 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.89740224 |
| 124 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.89546492 |
| 125 | Limb-girdle muscle atrophy (HP:0003797) | 1.89487464 |
| 126 | Malnutrition (HP:0004395) | 1.88032223 |
| 127 | Purpura (HP:0000979) | 1.87943541 |
| 128 | Mesangial abnormality (HP:0001966) | 1.86923103 |
| 129 | Pallor (HP:0000980) | 1.86080186 |
| 130 | Alopecia of scalp (HP:0002293) | 1.85739106 |
| 131 | Mitral regurgitation (HP:0001653) | 1.84642900 |
| 132 | Right ventricular cardiomyopathy (HP:0011663) | 1.84242660 |
| 133 | Shallow orbits (HP:0000586) | 1.83572567 |
| 134 | Acanthosis nigricans (HP:0000956) | 1.82725292 |
| 135 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.82637558 |
| 136 | Congenital, generalized hypertrichosis (HP:0004540) | 1.82242465 |
| 137 | Blue sclerae (HP:0000592) | 1.82032301 |
| 138 | Bone pain (HP:0002653) | 1.81638472 |
| 139 | Hand muscle atrophy (HP:0009130) | 1.79549579 |
| 140 | Arterial thrombosis (HP:0004420) | 1.79167910 |
| 141 | Prolonged neonatal jaundice (HP:0006579) | 1.78813465 |
| 142 | Cellulitis (HP:0100658) | 1.78450798 |
| 143 | Advanced eruption of teeth (HP:0006288) | 1.78252697 |
| 144 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.77914795 |
| 145 | Easy fatigability (HP:0003388) | 1.77890487 |
| 146 | Myositis (HP:0100614) | 1.77760076 |
| 147 | Pulmonary artery stenosis (HP:0004415) | 1.77648395 |
| 148 | Arterial tortuosity (HP:0005116) | 1.77356875 |
| 149 | Enlarged penis (HP:0000040) | 1.76842285 |
| 150 | Elbow flexion contracture (HP:0002987) | 1.76802803 |
| 151 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.76453450 |
| 152 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.75709653 |
| 153 | Bladder diverticulum (HP:0000015) | 1.74097480 |
| 154 | Muscle fiber splitting (HP:0003555) | 1.71340988 |
| 155 | Upper motor neuron abnormality (HP:0002127) | 1.71028890 |
| 156 | Ventricular tachycardia (HP:0004756) | 1.70807389 |
| 157 | Mitral stenosis (HP:0001718) | 1.67969930 |
| 158 | Thick nail (HP:0001805) | 1.66596571 |
| 159 | Lower limb amyotrophy (HP:0007210) | 1.66118133 |
| 160 | Hypertriglyceridemia (HP:0002155) | 1.65815170 |
| 161 | Neuronal loss in central nervous system (HP:0002529) | 1.65311124 |
| 162 | Abnormality of the thoracic spine (HP:0100711) | 1.65196674 |
| 163 | Apathy (HP:0000741) | 1.64789681 |
| 164 | Abnormality of carpal bone ossification (HP:0006257) | 1.64623420 |
| 165 | Hypercholesterolemia (HP:0003124) | 1.64519569 |
| 166 | Diminished motivation (HP:0000745) | 1.62271559 |
| 167 | Paraparesis (HP:0002385) | 1.62250112 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST1R | 4.70430508 |
| 2 | TRIB3 | 3.84206562 |
| 3 | NME2 | 3.81168635 |
| 4 | TIE1 | 3.78305904 |
| 5 | TGFBR2 | 3.70472530 |
| 6 | MAP2K3 | 3.34250908 |
| 7 | MAP3K3 | 3.13135484 |
| 8 | TGFBR1 | 3.04287256 |
| 9 | MUSK | 3.04052557 |
| 10 | TESK1 | 2.60321386 |
| 11 | EEF2K | 2.60307835 |
| 12 | PKN2 | 2.50992823 |
| 13 | KIT | 2.41889165 |
| 14 | ERN1 | 2.25206300 |
| 15 | MET | 2.19429828 |
| 16 | TTN | 2.17535563 |
| 17 | MAP4K1 | 2.07916246 |
| 18 | ICK | 1.98196826 |
| 19 | LMTK2 | 1.96730930 |
| 20 | PRPF4B | 1.81575931 |
| 21 | SMG1 | 1.72156009 |
| 22 | JAK3 | 1.70601579 |
| 23 | LRRK2 | 1.55358193 |
| 24 | RPS6KB2 | 1.52740759 |
| 25 | CAMKK2 | 1.51485783 |
| 26 | MYLK | 1.50559681 |
| 27 | RIPK1 | 1.47853216 |
| 28 | EPHB2 | 1.47830539 |
| 29 | PRKG2 | 1.47246674 |
| 30 | CDK19 | 1.46533326 |
| 31 | NTRK1 | 1.42937277 |
| 32 | MAPKAPK5 | 1.42087399 |
| 33 | TESK2 | 1.42065289 |
| 34 | MAP3K11 | 1.41016192 |
| 35 | ARAF | 1.39040795 |
| 36 | EPHA3 | 1.37962526 |
| 37 | PRKD2 | 1.34643774 |
| 38 | ABL2 | 1.29744811 |
| 39 | PRKD3 | 1.28323715 |
| 40 | KDR | 1.27932066 |
| 41 | DYRK3 | 1.26798530 |
| 42 | LIMK1 | 1.24423375 |
| 43 | EPHB1 | 1.23076904 |
| 44 | PIM2 | 1.20275808 |
| 45 | RPS6KA4 | 1.19070401 |
| 46 | ILK | 1.18309113 |
| 47 | MAPKAPK3 | 1.17747847 |
| 48 | BTK | 1.13319170 |
| 49 | TAOK2 | 1.12191579 |
| 50 | CDC42BPA | 1.09986473 |
| 51 | TBK1 | 1.07502864 |
| 52 | PAK2 | 1.07026456 |
| 53 | BCKDK | 1.05620561 |
| 54 | PTK6 | 1.03260106 |
| 55 | SCYL2 | 1.02370364 |
| 56 | PAK4 | 0.98735496 |
| 57 | LATS2 | 0.96746962 |
| 58 | CAMK1D | 0.95631046 |
| 59 | MATK | 0.95388811 |
| 60 | MAPK15 | 0.91837907 |
| 61 | FLT3 | 0.90668533 |
| 62 | IKBKB | 0.85514968 |
| 63 | TRPM7 | 0.85513857 |
| 64 | DDR2 | 0.85174229 |
| 65 | CSF1R | 0.83790240 |
| 66 | MOS | 0.81049190 |
| 67 | ZAP70 | 0.79493897 |
| 68 | ERBB4 | 0.77817820 |
| 69 | CAMK2G | 0.76322775 |
| 70 | MAP3K6 | 0.75929949 |
| 71 | NLK | 0.74743019 |
| 72 | FGFR4 | 0.74551215 |
| 73 | MAP2K2 | 0.72914025 |
| 74 | SIK1 | 0.72814565 |
| 75 | MAP3K13 | 0.71669899 |
| 76 | IKBKE | 0.70559728 |
| 77 | MTOR | 0.69926038 |
| 78 | HIPK2 | 0.69695451 |
| 79 | TEC | 0.68672945 |
| 80 | MARK2 | 0.66519372 |
| 81 | TYK2 | 0.66013622 |
| 82 | PDPK1 | 0.64709183 |
| 83 | DMPK | 0.63688903 |
| 84 | CAMK1 | 0.61998139 |
| 85 | PTK2 | 0.61726870 |
| 86 | MAPK12 | 0.61048170 |
| 87 | PIK3CA | 0.60582141 |
| 88 | PBK | 0.60555500 |
| 89 | ROCK2 | 0.59778192 |
| 90 | TYRO3 | 0.59215470 |
| 91 | EPHA2 | 0.58460478 |
| 92 | BMX | 0.57971773 |
| 93 | RPS6KA6 | 0.57601421 |
| 94 | HCK | 0.57402732 |
| 95 | RPS6KC1 | 0.55563132 |
| 96 | RPS6KL1 | 0.55563132 |
| 97 | ROCK1 | 0.55038310 |
| 98 | CDK8 | 0.54993327 |
| 99 | MAPK4 | 0.54078961 |
| 100 | TAOK1 | 0.53612612 |
| 101 | MKNK1 | 0.51715697 |
| 102 | PDGFRB | 0.51431545 |
| 103 | FER | 0.49994711 |
| 104 | ACVR1B | 0.49742707 |
| 105 | MAPKAPK2 | 0.48866298 |
| 106 | MAP3K14 | 0.48090418 |
| 107 | MAPK11 | 0.47251159 |
| 108 | CAMK2B | 0.47183269 |
| 109 | CAMKK1 | 0.47088164 |
| 110 | DAPK3 | 0.45737704 |
| 111 | CDK12 | 0.45363902 |
| 112 | KSR2 | 0.43369008 |
| 113 | CAMK2D | 0.43303756 |
| 114 | SYK | 0.43073620 |
| 115 | TNK2 | 0.42682807 |
| 116 | SIK3 | 0.41200470 |
| 117 | PRKCH | 0.40721937 |
| 118 | PDGFRA | 0.39591335 |
| 119 | IRAK3 | 0.39486263 |
| 120 | MAP3K2 | 0.38532270 |
| 121 | NEK9 | 0.38366549 |
| 122 | MAP2K6 | 0.38185873 |
| 123 | MAP3K8 | 0.38038394 |
| 124 | MAPK7 | 0.37948499 |
| 125 | MAP3K1 | 0.37594479 |
| 126 | RPS6KA2 | 0.37409130 |
| 127 | PHKG1 | 0.37367663 |
| 128 | PHKG2 | 0.37367663 |
| 129 | PRKD1 | 0.37294975 |
| 130 | DAPK1 | 0.37115226 |
| 131 | PDK2 | 0.36002905 |
| 132 | BRAF | 0.35573941 |
| 133 | IRAK4 | 0.35288999 |
| 134 | RET | 0.34164626 |
| 135 | CDK9 | 0.33841380 |
| 136 | CAMK4 | 0.33736460 |
| 137 | CSK | 0.32752341 |
| 138 | SRC | 0.32373537 |
| 139 | GSK3A | 0.30889909 |
| 140 | CDK7 | 0.30547380 |
| 141 | PIM1 | 0.30374430 |
| 142 | FGFR3 | 0.30037688 |
| 143 | RPS6KA5 | 0.29831323 |
| 144 | GRK7 | 0.29613086 |
| 145 | PIK3CG | 0.29018995 |
| 146 | MAPK3 | 0.28367032 |
| 147 | CDK6 | 0.27675315 |
| 148 | CAMK1G | 0.27201184 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.86067549 |
| 2 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 3.13847879 |
| 3 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.91741916 |
| 4 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.35336125 |
| 5 | Platelet activation_Homo sapiens_hsa04611 | 2.32144661 |
| 6 | Prion diseases_Homo sapiens_hsa05020 | 2.30527120 |
| 7 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.12650345 |
| 8 | Focal adhesion_Homo sapiens_hsa04510 | 2.02218474 |
| 9 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.93633622 |
| 10 | Malaria_Homo sapiens_hsa05144 | 1.85887832 |
| 11 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.72520015 |
| 12 | Galactose metabolism_Homo sapiens_hsa00052 | 1.58753824 |
| 13 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.55893569 |
| 14 | Other glycan degradation_Homo sapiens_hsa00511 | 1.54519936 |
| 15 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.54143867 |
| 16 | Leishmaniasis_Homo sapiens_hsa05140 | 1.53948473 |
| 17 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.51395033 |
| 18 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.46263255 |
| 19 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.45891492 |
| 20 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.45096544 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.44495749 |
| 22 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.37638946 |
| 23 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.33481863 |
| 24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.32757186 |
| 25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.32008266 |
| 26 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.30921584 |
| 27 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.30448542 |
| 28 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.30341043 |
| 29 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.29658413 |
| 30 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.28831007 |
| 31 | Shigellosis_Homo sapiens_hsa05131 | 1.27632465 |
| 32 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.26488186 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.25665052 |
| 34 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.24667281 |
| 35 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.24166912 |
| 36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.20731692 |
| 37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.19163182 |
| 38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.18877270 |
| 39 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.18794053 |
| 40 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.18165064 |
| 41 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.17721801 |
| 42 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.16695493 |
| 43 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.15183583 |
| 44 | Measles_Homo sapiens_hsa05162 | 1.14195763 |
| 45 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.12797993 |
| 46 | Pertussis_Homo sapiens_hsa05133 | 1.12690914 |
| 47 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.10826747 |
| 48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.09926191 |
| 49 | Bile secretion_Homo sapiens_hsa04976 | 1.09083306 |
| 50 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.08611805 |
| 51 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.08179182 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 1.08007495 |
| 53 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.07495269 |
| 54 | Amoebiasis_Homo sapiens_hsa05146 | 1.06849173 |
| 55 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.06059818 |
| 56 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.05169938 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.05114537 |
| 58 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.04857287 |
| 59 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.04156732 |
| 60 | Hepatitis B_Homo sapiens_hsa05161 | 1.02402567 |
| 61 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.02223757 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99838500 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.98668924 |
| 64 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.98275949 |
| 65 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.95370065 |
| 66 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.94876798 |
| 67 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93944967 |
| 68 | Histidine metabolism_Homo sapiens_hsa00340 | 0.93581822 |
| 69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.92840153 |
| 70 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.91948764 |
| 71 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.90386567 |
| 72 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.90122129 |
| 73 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.89585735 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.89366020 |
| 75 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.88948803 |
| 76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.85531972 |
| 77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.85492053 |
| 78 | Hepatitis C_Homo sapiens_hsa05160 | 0.84370208 |
| 79 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.83812905 |
| 80 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.83635574 |
| 81 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.83328232 |
| 82 | Salmonella infection_Homo sapiens_hsa05132 | 0.82489999 |
| 83 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.82310673 |
| 84 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.81942198 |
| 85 | Endocytosis_Homo sapiens_hsa04144 | 0.81158802 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.79168753 |
| 87 | Insulin resistance_Homo sapiens_hsa04931 | 0.78928918 |
| 88 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.76278538 |
| 89 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76270105 |
| 90 | Pathways in cancer_Homo sapiens_hsa05200 | 0.72117044 |
| 91 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.67141918 |
| 92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.66870099 |
| 93 | Glioma_Homo sapiens_hsa05214 | 0.66699000 |
| 94 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.66328352 |
| 95 | Legionellosis_Homo sapiens_hsa05134 | 0.65383765 |
| 96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.65261338 |
| 97 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.65134723 |
| 98 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.64735712 |
| 99 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.64325210 |
| 100 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.63867900 |
| 101 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.63044747 |
| 102 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.62942640 |
| 103 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.62903261 |
| 104 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.62611784 |
| 105 | Phagosome_Homo sapiens_hsa04145 | 0.62073720 |
| 106 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.62071011 |
| 107 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.61487532 |
| 108 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.61098255 |
| 109 | Bladder cancer_Homo sapiens_hsa05219 | 0.60459986 |
| 110 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.58453987 |
| 111 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.57539546 |
| 112 | Influenza A_Homo sapiens_hsa05164 | 0.56439104 |
| 113 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.55651610 |
| 114 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.55339238 |
| 115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.55179292 |
| 116 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.55110299 |
| 117 | Lysosome_Homo sapiens_hsa04142 | 0.55004945 |
| 118 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54362320 |
| 119 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.53300523 |
| 120 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.52944827 |
| 121 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.52707635 |
| 122 | Carbon metabolism_Homo sapiens_hsa01200 | 0.52678755 |
| 123 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.52493574 |
| 124 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51780352 |
| 125 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.50445190 |
| 126 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50127750 |
| 127 | Viral myocarditis_Homo sapiens_hsa05416 | 0.49890050 |
| 128 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.49878858 |
| 129 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.49102893 |
| 130 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.48433114 |
| 131 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48255831 |
| 132 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.48213664 |
| 133 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.46100073 |
| 134 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45364183 |
| 135 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44412110 |
| 136 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.41838868 |
| 137 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.38875105 |
| 138 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.38438930 |
| 139 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.38065711 |
| 140 | Endometrial cancer_Homo sapiens_hsa05213 | 0.36269400 |
| 141 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.36070321 |
| 142 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.35887653 |
| 143 | Tuberculosis_Homo sapiens_hsa05152 | 0.33777786 |
| 144 | RNA degradation_Homo sapiens_hsa03018 | 0.32697475 |
| 145 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.32518399 |
| 146 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.32325302 |
| 147 | Adherens junction_Homo sapiens_hsa04520 | 0.31901805 |
| 148 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.31846734 |

