TRIM56

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.69542842
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.69542842
3positive regulation of gamma-delta T cell activation (GO:0046645)5.28153233
4antigen processing and presentation of endogenous antigen (GO:0019883)5.24049302
5regulation of gamma-delta T cell differentiation (GO:0045586)4.52334573
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.33450777
7regulation of gamma-delta T cell activation (GO:0046643)4.23998458
8cellular response to exogenous dsRNA (GO:0071360)4.13435928
9positive thymic T cell selection (GO:0045059)3.91244430
10positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.71745359
11regulation of interleukin-12 biosynthetic process (GO:0045075)3.55236338
12positive regulation of histone deacetylation (GO:0031065)3.44027932
13regulation of interferon-beta biosynthetic process (GO:0045357)3.40356417
14mannose metabolic process (GO:0006013)3.36271061
15JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.23991479
16germinal center formation (GO:0002467)3.22728543
17cellular response to type I interferon (GO:0071357)3.21263795
18* response to type I interferon (GO:0034340)3.21263795
19type I interferon signaling pathway (GO:0060337)3.21263795
20positive regulation of natural killer cell differentiation (GO:0032825)3.18420474
21positive T cell selection (GO:0043368)3.16840965
22positive regulation of interferon-alpha production (GO:0032727)3.12723546
23macrophage activation involved in immune response (GO:0002281)3.10988197
24negative T cell selection (GO:0043383)3.04541845
25positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.03783189
26thymic T cell selection (GO:0045061)2.98859909
27regulation of interferon-alpha production (GO:0032647)2.97346275
28striated muscle atrophy (GO:0014891)2.96214693
29negative thymic T cell selection (GO:0045060)2.93892274
30CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.91071725
31detection of bacterium (GO:0016045)2.90802391
32detection of other organism (GO:0098543)2.88508118
33positive regulation of defense response to virus by host (GO:0002230)2.88057106
34hepatocyte apoptotic process (GO:0097284)2.87080385
35T cell selection (GO:0045058)2.86799451
36antigen processing and presentation via MHC class Ib (GO:0002475)2.85548688
37interferon-gamma secretion (GO:0072643)2.83242821
38positive regulation of fatty acid beta-oxidation (GO:0032000)2.83012426
39regulation of type I interferon-mediated signaling pathway (GO:0060338)2.81009094
40positive regulation of B cell differentiation (GO:0045579)2.80402139
41regulation of MHC class I biosynthetic process (GO:0045343)2.79030453
42growth hormone receptor signaling pathway (GO:0060396)2.72978703
43response to interleukin-15 (GO:0070672)2.71667378
44positive regulation of CREB transcription factor activity (GO:0032793)2.70920126
45interferon-gamma production (GO:0032609)2.69503670
46definitive hemopoiesis (GO:0060216)2.68843143
47regulation of dendritic cell antigen processing and presentation (GO:0002604)2.65233327
48negative regulation of lymphocyte mediated immunity (GO:0002707)2.65173267
49regulation of necroptotic process (GO:0060544)2.64934067
50negative regulation of erythrocyte differentiation (GO:0045647)2.64337684
51leukocyte aggregation (GO:0070486)2.63425270
52regulation of T cell tolerance induction (GO:0002664)2.63275081
53negative regulation of T cell mediated immunity (GO:0002710)2.63186175
54detection of external biotic stimulus (GO:0098581)2.62045094
55regulation of B cell differentiation (GO:0045577)2.61245290
56negative regulation of innate immune response (GO:0045824)2.57844485
57regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.57831858
58regulation of natural killer cell differentiation (GO:0032823)2.56690371
59response to protozoan (GO:0001562)2.55295860
60response to peptidoglycan (GO:0032494)2.55139993
61T-helper 1 type immune response (GO:0042088)2.53551736
62response to interferon-alpha (GO:0035455)2.52653065
63positive regulation of protein deacetylation (GO:0090312)2.51706922
64defense response to protozoan (GO:0042832)2.51146392
65interferon-gamma-mediated signaling pathway (GO:0060333)2.51073133
66positive regulation of antigen processing and presentation (GO:0002579)2.50698677
67negative regulation of cell killing (GO:0031342)2.50254454
68negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.50254454
69response to muramyl dipeptide (GO:0032495)2.50037361
70B cell receptor signaling pathway (GO:0050853)2.49658256
71regulation of B cell receptor signaling pathway (GO:0050855)2.49220383
72regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.48887036
73detection of molecule of bacterial origin (GO:0032490)2.47489401
74response to host (GO:0075136)2.47223305
75response to host defenses (GO:0052200)2.47223305
76response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.47223305
77cellular response to zinc ion (GO:0071294)2.46980170
78regulation of antigen processing and presentation (GO:0002577)2.45854707
79regulation of response to interferon-gamma (GO:0060330)2.44565621
80negative regulation of viral genome replication (GO:0045071)2.43446749
81regulation of interferon-beta production (GO:0032648)2.42735087
82positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.42360629
83natural killer cell differentiation (GO:0001779)2.41533647
84negative regulation of fatty acid transport (GO:2000192)2.41451317
85modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.40874487
86modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.40874487
87positive regulation by organism of defense response of other organism involved in symbiotic interact2.40874487
88modulation by symbiont of host immune response (GO:0052553)2.40874487
89positive regulation by symbiont of host defense response (GO:0052509)2.40874487
90modulation by symbiont of host defense response (GO:0052031)2.40874487
91response to host immune response (GO:0052572)2.40128683
92response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.40128683
93negative regulation of interleukin-6 production (GO:0032715)2.40016886
94immunoglobulin mediated immune response (GO:0016064)2.39091511
95tolerance induction (GO:0002507)2.38943720
96response to laminar fluid shear stress (GO:0034616)2.38157067
97negative regulation of leukocyte mediated immunity (GO:0002704)2.37739135
98microglial cell activation (GO:0001774)2.37734325
99positive regulation of T cell mediated cytotoxicity (GO:0001916)2.36946116
100negative regulation of interleukin-12 production (GO:0032695)2.36145834
101regulation of extracellular matrix disassembly (GO:0010715)2.35417215
102skeletal muscle adaptation (GO:0043501)2.35252910
103T cell migration (GO:0072678)2.34912499
104regulation of T cell mediated cytotoxicity (GO:0001914)2.34402541
105leukocyte cell-cell adhesion (GO:0007159)2.33839985
106regulation of fatty acid beta-oxidation (GO:0031998)2.33777769
107valine metabolic process (GO:0006573)2.32576871
108cellular response to growth hormone stimulus (GO:0071378)2.32364656
109positive regulation of humoral immune response (GO:0002922)2.32326063
110positive regulation of protein kinase C signaling (GO:0090037)2.31425140
111regulation of endothelial cell chemotaxis (GO:2001026)2.31390391
112negative regulation of phagocytosis (GO:0050765)2.30686920
113regulation of alpha-beta T cell proliferation (GO:0046640)2.30471776
114regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.30255739
115positive regulation of fatty acid oxidation (GO:0046321)2.30227460
116regulation of histone deacetylation (GO:0031063)2.30027120
117detection of biotic stimulus (GO:0009595)2.29919966
118T cell costimulation (GO:0031295)2.29884671
119cellular response to virus (GO:0098586)2.28492652
120regulation of cholesterol storage (GO:0010885)2.27504400
121positive regulation of tolerance induction (GO:0002645)2.26751947
122cellular extravasation (GO:0045123)2.26596064
123lymphocyte costimulation (GO:0031294)2.24694155
124positive regulation of granulocyte differentiation (GO:0030854)2.23679367
125histone H3-K36 demethylation (GO:0070544)2.23417547
126regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.23264992
127lymph node development (GO:0048535)2.23255973
128negative regulation of bone resorption (GO:0045779)2.22746385
129megakaryocyte development (GO:0035855)2.22461201
130T cell homeostasis (GO:0043029)2.21610876
131lymphocyte homeostasis (GO:0002260)2.21306484
132angiogenesis involved in wound healing (GO:0060055)2.21291203
133low-density lipoprotein particle clearance (GO:0034383)2.19566143
134positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.18590617
135JAK-STAT cascade (GO:0007259)2.17476885
136vascular endothelial growth factor signaling pathway (GO:0038084)2.17331187
137positive regulation of interferon-beta production (GO:0032728)2.16523186
138NIK/NF-kappaB signaling (GO:0038061)2.15852496
139regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.15118058
140negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.14900308
141cytoplasmic mRNA processing body assembly (GO:0033962)2.14737661
142negative regulation of B cell proliferation (GO:0030889)2.13826832
143establishment of endothelial barrier (GO:0061028)2.13586772
144positive regulation of macrophage differentiation (GO:0045651)2.12832783
145antigen receptor-mediated signaling pathway (GO:0050851)2.12589780
146embryonic hemopoiesis (GO:0035162)2.12544468
147negative regulation of stress fiber assembly (GO:0051497)2.12481146
148cellular response to interferon-alpha (GO:0035457)2.11838100
149regulation of tolerance induction (GO:0002643)2.10649902
150negative regulation of granulocyte differentiation (GO:0030853)2.07934877
151natural killer cell activation (GO:0030101)2.07134505
152regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.05554436

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.87046234
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.42509057
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.99781837
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.56663139
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.14959916
6GATA1_22025678_ChIP-Seq_K562_Human3.10786641
7* IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.78168169
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.73327817
9ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.69038679
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.66141980
11* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.58955175
12MYC_22102868_ChIP-Seq_BL_Human2.43508819
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.42670351
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.40041373
15IRF8_21731497_ChIP-ChIP_J774_Mouse2.38709801
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.36615029
17NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.35485076
18STAT6_21828071_ChIP-Seq_BEAS2B_Human2.33999073
19RUNX_20019798_ChIP-Seq_JUKART_Human2.32422031
20SCL_19346495_ChIP-Seq_HPC-7_Human2.32299734
21IRF8_27001747_Chip-Seq_BMDM_Mouse2.30889070
22FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.19727256
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.17733687
24PPARA_22158963_ChIP-Seq_LIVER_Mouse2.16962988
25RXR_22158963_ChIP-Seq_LIVER_Mouse2.14831463
26* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.12778469
27MAF_26560356_Chip-Seq_TH1_Human2.11153134
28MYB_21317192_ChIP-Seq_ERMYB_Mouse2.06477906
29MYB_26560356_Chip-Seq_TH2_Human2.05016144
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.02572117
31ESR2_21235772_ChIP-Seq_MCF-7_Human1.96791886
32STAT4_19710469_ChIP-ChIP_TH1__Mouse1.95564860
33PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.94896817
34LXR_22158963_ChIP-Seq_LIVER_Mouse1.93518233
35* VDR_21846776_ChIP-Seq_THP-1_Human1.92784869
36BRD4_27068464_Chip-Seq_AML-cells_Mouse1.89318367
37* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.89028220
38* TCF7_22412390_ChIP-Seq_EML_Mouse1.87115780
39MYB_26560356_Chip-Seq_TH1_Human1.86193484
40UTX_26944678_Chip-Seq_JUKART_Human1.85348635
41LXR_22292898_ChIP-Seq_THP-1_Human1.77654234
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.74173636
43* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.71419711
44STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.71104375
45DROSHA_22980978_ChIP-Seq_HELA_Human1.68202246
46EGR1_23403033_ChIP-Seq_LIVER_Mouse1.65558677
47ESR1_21235772_ChIP-Seq_MCF-7_Human1.64683867
48ESR1_20079471_ChIP-ChIP_T-47D_Human1.62378739
49GATA1_19941826_ChIP-Seq_K562_Human1.61466309
50KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.61289002
51* VDR_24763502_ChIP-Seq_THP-1_Human1.60700529
52CLOCK_20551151_ChIP-Seq_293T_Human1.59083973
53RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.56120971
54* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.55310320
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52925379
56ELK3_25401928_ChIP-Seq_HUVEC_Human1.52481002
57* GATA2_21666600_ChIP-Seq_HMVEC_Human1.50739627
58* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.50648755
59RUNX1_22412390_ChIP-Seq_EML_Mouse1.49897836
60KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.49489151
61* RUNX1_27514584_Chip-Seq_MCF-7_Human1.45539989
62ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.44579919
63RACK7_27058665_Chip-Seq_MCF-7_Human1.43840641
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40182207
65SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.40058071
66KDM2B_26808549_Chip-Seq_SUP-B15_Human1.39451031
67KDM2B_26808549_Chip-Seq_DND41_Human1.39293352
68SPI1_23127762_ChIP-Seq_K562_Human1.38845174
69RARG_19884340_ChIP-ChIP_MEFs_Mouse1.37948461
70GATA1_19941827_ChIP-Seq_MEL_Mouse1.37167960
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.36837115
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.34679204
73SMAD_19615063_ChIP-ChIP_OVARY_Human1.34425284
74FOXO3_23340844_ChIP-Seq_DLD1_Human1.32965729
75GATA3_27048872_Chip-Seq_THYMUS_Human1.31617133
76* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.31579496
77* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.31214973
78VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.30918460
79* GATA2_19941826_ChIP-Seq_K562_Human1.30306995
80EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30045980
81NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.28889931
82* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.28798558
83TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.27643619
84PU_27001747_Chip-Seq_BMDM_Mouse1.25629860
85SMC4_20622854_ChIP-Seq_HELA_Human1.24313544
86TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.24075876
87SPI1_23547873_ChIP-Seq_NB4_Human1.24065063
88BCOR_27268052_Chip-Seq_Bcells_Human1.21936175
89GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21309010
90* P68_20966046_ChIP-Seq_HELA_Human1.19059992
91THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.18170287
92MAF_26560356_Chip-Seq_TH2_Human1.17934323
93BCL6_27268052_Chip-Seq_Bcells_Human1.16737298
94FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.15581570
95NCOR1_26117541_ChIP-Seq_K562_Human1.13250931
96TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12154909
97GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10452717
98AHR_22903824_ChIP-Seq_MCF-7_Human1.09949348
99P63_26484246_Chip-Seq_KERATINOCYTES_Human1.09862109
100* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.08822861
101FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.08721874
102* TP63_22573176_ChIP-Seq_HFKS_Human1.08200753
103PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06102698
104ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05530114
105SOX2_27498859_Chip-Seq_STOMACH_Mouse1.05376075
106BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.05313819
107* KDM2B_26808549_Chip-Seq_K562_Human1.04452490
108ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02826258
109LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.02440463
110RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01928784
111TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01893340
112* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.01493664
113* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.01493664
114CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01491119
115* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.01144348
116GATA6_25053715_ChIP-Seq_YYC3_Human1.01060293
117SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00900688
118* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.98591882
119E2F7_22180533_ChIP-Seq_HELA_Human0.97550156
120KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96825570
121LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.95986841
122* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.95920107
123E2F1_20622854_ChIP-Seq_HELA_Human0.94369765
124STAT1_20625510_ChIP-Seq_HELA_Human0.94029402
125SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93555052
126KDM2B_26808549_Chip-Seq_JURKAT_Human0.93461660
127GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92686421
128* CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.92396868
129VDR_24787735_ChIP-Seq_THP-1_Human0.91754566
130CREB1_26743006_Chip-Seq_LNCaP_Human0.91393612
131CTCF_27219007_Chip-Seq_ERYTHROID_Human0.90963714
132ELF1_20517297_ChIP-Seq_JURKAT_Human0.90897414
133TBX20_22080862_ChIP-Seq_HEART_Mouse0.90521752
134TBX20_22328084_ChIP-Seq_HEART_Mouse0.90521752
135CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88125928
136FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.87786550

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003300_gastrointestinal_ulcer3.03851609
2MP0002166_altered_tumor_susceptibility2.61907969
3MP0001835_abnormal_antigen_presentation2.60870348
4MP0000685_abnormal_immune_system2.45192568
5MP0003303_peritoneal_inflammation2.32144924
6MP0005387_immune_system_phenotype2.27658798
7MP0001790_abnormal_immune_system2.27658798
8MP0003436_decreased_susceptibility_to2.14056091
9MP0003763_abnormal_thymus_physiology2.10371251
10MP0001800_abnormal_humoral_immune2.05819733
11MP0005671_abnormal_response_to1.97683751
12MP0002006_tumorigenesis1.96416365
13MP0010352_gastrointestinal_tract_polyps1.96312497
14MP0003724_increased_susceptibility_to1.96299712
15MP0009785_altered_susceptibility_to1.85961315
16MP0004947_skin_inflammation1.84840861
17MP0004381_abnormal_hair_follicle1.83208843
18MP0003705_abnormal_hypodermis_morpholog1.81565205
19MP0005000_abnormal_immune_tolerance1.78872559
20MP0005025_abnormal_response_to1.76453958
21MP0002452_abnormal_antigen_presenting1.76328514
22MP0010155_abnormal_intestine_physiology1.71096941
23MP0005464_abnormal_platelet_physiology1.68707071
24MP0002723_abnormal_immune_serum1.68463245
25MP0009278_abnormal_bone_marrow1.68012911
26MP0005360_urolithiasis1.65163534
27MP0002420_abnormal_adaptive_immunity1.61832837
28MP0001819_abnormal_immune_cell1.60845425
29MP0004808_abnormal_hematopoietic_stem1.59578302
30MP0001873_stomach_inflammation1.58160937
31MP0002398_abnormal_bone_marrow1.57624652
32MP0003172_abnormal_lysosome_physiology1.55281620
33MP0006054_spinal_hemorrhage1.55020245
34MP0002419_abnormal_innate_immunity1.51599091
35MP0001545_abnormal_hematopoietic_system1.50967645
36MP0005397_hematopoietic_system_phenotyp1.50967645
37MP0003566_abnormal_cell_adhesion1.50255807
38MP0002138_abnormal_hepatobiliary_system1.49671654
39MP0003191_abnormal_cellular_cholesterol1.48885925
40MP0002396_abnormal_hematopoietic_system1.48630458
41MP0002405_respiratory_system_inflammati1.44738980
42MP0003252_abnormal_bile_duct1.44395097
43MP0010234_abnormal_vibrissa_follicle1.44159368
44MP0002877_abnormal_melanocyte_morpholog1.43892449
45MP0003183_abnormal_peptide_metabolism1.41457971
46MP0000716_abnormal_immune_system1.39111574
47MP0002139_abnormal_hepatobiliary_system1.38788110
48MP0003656_abnormal_erythrocyte_physiolo1.36733401
49MP0001845_abnormal_inflammatory_respons1.34900545
50MP0002722_abnormal_immune_system1.34118136
51MP0000689_abnormal_spleen_morphology1.33454390
52MP0001853_heart_inflammation1.31954620
53MP0002132_abnormal_respiratory_system1.30418303
54MP0004883_abnormal_blood_vessel1.29980074
55MP0002148_abnormal_hypersensitivity_rea1.28692096
56MP0005023_abnormal_wound_healing1.27586709
57MP0005365_abnormal_bile_salt1.27350745
58MP0003279_aneurysm1.27280428
59MP0005164_abnormal_response_to1.26559892
60MP0010368_abnormal_lymphatic_system1.24982804
61MP0001879_abnormal_lymphatic_vessel1.24176755
62MP0001958_emphysema1.24051995
63MP0008438_abnormal_cutaneous_collagen1.22169131
64MP0001533_abnormal_skeleton_physiology1.20855533
65MP0002429_abnormal_blood_cell1.20539385
66MP0004043_abnormal_pH_regulation1.18745965
67MP0004510_myositis1.18559440
68MP0003045_fibrosis1.17886109
69MP0000703_abnormal_thymus_morphology1.17412783
70MP0000609_abnormal_liver_physiology1.16415146
71MP0006082_CNS_inflammation1.16117187
72MP0001663_abnormal_digestive_system1.16078730
73MP0005076_abnormal_cell_differentiation1.15379421
74MP0005670_abnormal_white_adipose1.15216652
75MP0000465_gastrointestinal_hemorrhage1.14240528
76MP0008469_abnormal_protein_level1.14223022
77MP0003866_abnormal_defecation1.10831813
78MP0009333_abnormal_splenocyte_physiolog1.10307911
79MP0000678_abnormal_parathyroid_gland1.09749947
80MP0009840_abnormal_foam_cell1.07488790
81MP0005503_abnormal_tendon_morphology1.07360996
82MP0003453_abnormal_keratinocyte_physiol1.06137942
83MP0003828_pulmonary_edema1.03860445
84MP0009764_decreased_sensitivity_to1.02592357
85MP0002933_joint_inflammation1.01901350
86MP0005451_abnormal_body_composition0.99663942
87MP0003195_calcinosis0.98849090
88MP0000858_altered_metastatic_potential0.98645475
89MP0002998_abnormal_bone_remodeling0.98416645
90MP0010307_abnormal_tumor_latency0.98253699
91MP0010329_abnormal_lipoprotein_level0.97084946
92MP0009115_abnormal_fat_cell0.96100857
93MP0005085_abnormal_gallbladder_physiolo0.95992412
94MP0002168_other_aberrant_phenotype0.95033551
95MP0005390_skeleton_phenotype0.94928885
96MP0003091_abnormal_cell_migration0.94777956
97MP0002928_abnormal_bile_duct0.93218105
98MP0000383_abnormal_hair_follicle0.91917402
99MP0003448_altered_tumor_morphology0.91635863
100MP0000767_abnormal_smooth_muscle0.91240928
101MP0009643_abnormal_urine_homeostasis0.90405713
102MP0000490_abnormal_crypts_of0.90214267
103MP0002060_abnormal_skin_morphology0.89813563
104MP0002136_abnormal_kidney_physiology0.89628924
105MP0002254_reproductive_system_inflammat0.89205671
106MP0001666_abnormal_nutrient_absorption0.88355763
107MP0004858_abnormal_nervous_system0.87444334
108MP0005083_abnormal_biliary_tract0.87303852
109MP0004185_abnormal_adipocyte_glucose0.86273371
110MP0009763_increased_sensitivity_to0.86039572
111MP0005666_abnormal_adipose_tissue0.85310890
112MP0002009_preneoplasia0.84539912
113MP0004130_abnormal_muscle_cell0.83471245
114MP0001851_eye_inflammation0.81542504
115MP0001765_abnormal_ion_homeostasis0.80805286
116MP0000598_abnormal_liver_morphology0.80733808
117MP0001348_abnormal_lacrimal_gland0.80001698
118MP0005058_abnormal_lysosome_morphology0.79848743
119MP0005381_digestive/alimentary_phenotyp0.77995098
120MP0000470_abnormal_stomach_morphology0.77697818
121MP0005275_abnormal_skin_tensile0.77650011
122MP0008961_abnormal_basal_metabolism0.77648290
123MP0005310_abnormal_salivary_gland0.77614495
124MP0005409_darkened_coat_color0.76545167
125MP0000249_abnormal_blood_vessel0.75964687
126MP0005375_adipose_tissue_phenotype0.74426377
127MP0005167_abnormal_blood-brain_barrier0.72334666
128MP0001664_abnormal_digestion0.72213004
129MP0000371_diluted_coat_color0.71517908

Predicted human phenotypes

RankGene SetZ-score
1Recurrent viral infections (HP:0004429)3.46836729
2Autoimmune thrombocytopenia (HP:0001973)3.41697892
3Eczematoid dermatitis (HP:0000976)3.35241808
4T lymphocytopenia (HP:0005403)3.31492357
5Abnormality of the fingertips (HP:0001211)3.26369123
6Recurrent fungal infections (HP:0002841)3.24397405
7Abnormality of T cell number (HP:0011839)3.21700793
8Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.20776620
9Spontaneous hematomas (HP:0007420)3.09736869
10Retrobulbar optic neuritis (HP:0100654)3.02043061
11Optic neuritis (HP:0100653)3.02043061
12Chronic otitis media (HP:0000389)2.96019395
13Clumsiness (HP:0002312)2.94655446
14Pustule (HP:0200039)2.91325805
15Colitis (HP:0002583)2.90749047
16Increased neuronal autofluorescent lipopigment (HP:0002074)2.89380184
17Recurrent bronchitis (HP:0002837)2.88599053
18Abnormal delayed hypersensitivity skin test (HP:0002963)2.87806144
19Hematochezia (HP:0002573)2.86847292
20Genetic anticipation (HP:0003743)2.82109349
21Myocardial infarction (HP:0001658)2.81202497
22Inflammation of the large intestine (HP:0002037)2.79786979
23Abnormality of the nasal mucosa (HP:0000433)2.74264673
24Aortic aneurysm (HP:0004942)2.71027304
25Polycythemia (HP:0001901)2.68064201
26Increased cerebral lipofuscin (HP:0011813)2.66104365
27Gastrointestinal inflammation (HP:0004386)2.63333687
28Prolonged bleeding time (HP:0003010)2.63326923
29Abnormality of T cells (HP:0002843)2.60545625
30Abnormal platelet volume (HP:0011876)2.58980515
31Nasal polyposis (HP:0100582)2.58689455
32Recurrent cutaneous fungal infections (HP:0011370)2.57673058
33Chronic mucocutaneous candidiasis (HP:0002728)2.57673058
34Cellulitis (HP:0100658)2.57190288
35Agammaglobulinemia (HP:0004432)2.55216725
36Interstitial pulmonary disease (HP:0006530)2.52388189
37Gingival bleeding (HP:0000225)2.52355348
38Malnutrition (HP:0004395)2.51599243
39Panhypogammaglobulinemia (HP:0003139)2.49782022
40Recurrent abscess formation (HP:0002722)2.47769756
41Obstructive sleep apnea (HP:0002870)2.46166706
42Periodontitis (HP:0000704)2.44250403
43Cerebral aneurysm (HP:0004944)2.44134977
44Poikilocytosis (HP:0004447)2.43923996
45Broad face (HP:0000283)2.43160489
46Elevated erythrocyte sedimentation rate (HP:0003565)2.41635894
47Dynein arm defect of respiratory motile cilia (HP:0012255)2.41422745
48Absent/shortened dynein arms (HP:0200106)2.41422745
49Increased mean platelet volume (HP:0011877)2.37023126
50Epistaxis (HP:0000421)2.35341546
51Abnormality of macrophages (HP:0004311)2.34683887
52Myositis (HP:0100614)2.32412594
53Increased IgE level (HP:0003212)2.31281327
54Abnormality of B cell number (HP:0010975)2.31209479
55B lymphocytopenia (HP:0010976)2.31209479
56Pulmonary infiltrates (HP:0002113)2.30014393
57Recurrent bacterial skin infections (HP:0005406)2.29454861
58Acanthocytosis (HP:0001927)2.28754043
59Esophageal varix (HP:0002040)2.23349131
60IgM deficiency (HP:0002850)2.22162899
61Recurrent gram-negative bacterial infections (HP:0005420)2.21310000
62Vasculitis (HP:0002633)2.20820705
63Recurrent sinusitis (HP:0011108)2.18758797
64Abnormality of T cell physiology (HP:0011840)2.17872883
65Impaired platelet aggregation (HP:0003540)2.15779943
66Abnormal platelet function (HP:0011869)2.15779943
67Osteolytic defects of the phalanges of the hand (HP:0009771)2.15448816
68Osteolytic defects of the hand bones (HP:0009699)2.15448816
69Thrombocytosis (HP:0001894)2.13450572
70Meningitis (HP:0001287)2.13221407
71Keratoconjunctivitis sicca (HP:0001097)2.12999168
72Recurrent skin infections (HP:0001581)2.12951528
73Eosinophilia (HP:0001880)2.12690240
74Papilloma (HP:0012740)2.12582039
75Verrucae (HP:0200043)2.12582039
76Encephalitis (HP:0002383)2.12030276
77Stomatitis (HP:0010280)2.11453137
78Arterial thrombosis (HP:0004420)2.11271017
79Emphysema (HP:0002097)2.10201033
80Menorrhagia (HP:0000132)2.09784606
81Mitral stenosis (HP:0001718)2.08800246
82Cheilitis (HP:0100825)2.04767230
83Deep venous thrombosis (HP:0002625)2.04375152
84Petechiae (HP:0000967)2.04074955
85Keratoconjunctivitis (HP:0001096)2.02092748
86Osteomyelitis (HP:0002754)2.00685545
87Decreased circulating renin level (HP:0003351)1.99377732
88Persistence of primary teeth (HP:0006335)1.98667413
89Lymphopenia (HP:0001888)1.98216284
90IgA deficiency (HP:0002720)1.96828296
91Abnormality of the common coagulation pathway (HP:0010990)1.96780140
92Thyroiditis (HP:0100646)1.96424872
93Severe combined immunodeficiency (HP:0004430)1.95148400
94Aneurysm (HP:0002617)1.94081059
95Restrictive lung disease (HP:0002091)1.93743787
96Aortic dissection (HP:0002647)1.93111932
97Combined immunodeficiency (HP:0005387)1.92785587
98Tetraparesis (HP:0002273)1.92191901
99Gastrointestinal stroma tumor (HP:0100723)1.92025138
100Gingivitis (HP:0000230)1.91423401
101Autoimmune hemolytic anemia (HP:0001890)1.91410660
102Dysostosis multiplex (HP:0000943)1.90751390
103Abnormality of cells of the lymphoid lineage (HP:0012140)1.89333248
104Leukocytosis (HP:0001974)1.89179994
105Chronic diarrhea (HP:0002028)1.88840726
106Urinary glycosaminoglycan excretion (HP:0003541)1.86093189
107Mucopolysacchariduria (HP:0008155)1.86093189
108Hypoplasia of the thymus (HP:0000778)1.85873962
109Granulocytopenia (HP:0001913)1.85455729
110Joint hemorrhage (HP:0005261)1.84741853
111Abnormality of mucopolysaccharide metabolism (HP:0011020)1.84405514
112Abnormality of polysaccharide metabolism (HP:0011012)1.84405514
113Abnormality of glycosaminoglycan metabolism (HP:0004371)1.84405514
114J-shaped sella turcica (HP:0002680)1.84084425
115Mitral valve prolapse (HP:0001634)1.82375372
116Bronchitis (HP:0012387)1.81415551
117Gastrointestinal infarctions (HP:0005244)1.80926788
118Orchitis (HP:0100796)1.79704055
119Microcytic anemia (HP:0001935)1.79431193
120Peritonitis (HP:0002586)1.77118564
121Thin bony cortex (HP:0002753)1.76799931
122Bronchiectasis (HP:0002110)1.75205275
123Abnormal ciliary motility (HP:0012262)1.74354081
124Bronchomalacia (HP:0002780)1.74228910
125Increased density of long bones (HP:0006392)1.74036256
126Hemorrhage of the eye (HP:0011885)1.73320820
127Aortic regurgitation (HP:0001659)1.73293402
128Abnormal respiratory motile cilium morphology (HP:0005938)1.72675232
129Abnormal respiratory epithelium morphology (HP:0012253)1.72675232
130Abnormality of the pleura (HP:0002103)1.72399482
131Subacute progressive viral hepatitis (HP:0006572)1.72147670
132Abnormality of the pericardium (HP:0001697)1.72087551
133Rectal prolapse (HP:0002035)1.71867640
134Obstructive lung disease (HP:0006536)1.71821325
135Chronic obstructive pulmonary disease (HP:0006510)1.71821325
136Cervical subluxation (HP:0003308)1.71322207
137Hemoptysis (HP:0002105)1.70536420
138Pulmonary embolism (HP:0002204)1.70006779
139Hypochromic anemia (HP:0001931)1.69708155
140Skin ulcer (HP:0200042)1.69517795
141Mediastinal lymphadenopathy (HP:0100721)1.68872270
142Dilatation of the ascending aorta (HP:0005111)1.68335073
143Chronic sinusitis (HP:0011109)1.67986975
144Polygenic inheritance (HP:0010982)1.67400098
145Abnormality of the endocardium (HP:0004306)1.66047473
146Hyperacusis (HP:0010780)1.65827311
147Protruding tongue (HP:0010808)1.64232868

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.31917800
2ERN12.82007045
3FGFR42.70917514
4TYK22.39045515
5TRIB32.23546677
6JAK32.22535025
7TBK12.18788735
8RIPK42.17522928
9IKBKE2.17001198
10MAP3K102.10197949
11JAK12.08854991
12TXK2.03620405
13STK102.02370867
14TAOK32.01387974
15FGFR31.99858470
16SIK11.99533156
17TGFBR21.97299845
18MAP3K141.95186490
19EEF2K1.94087237
20MAPK151.78742216
21CDC42BPA1.77951962
22PKN21.76107364
23TTN1.67342166
24ZAP701.66603374
25TNK21.62168694
26CDK121.54844790
27EPHB11.47091383
28PRPF4B1.45851838
29KIT1.43930197
30PTK61.43293875
31ITK1.40895826
32RIPK11.40744657
33LRRK21.39364193
34NLK1.38652270
35CAMK1D1.35652901
36EPHA31.33956435
37GRK61.33656206
38SMG11.32411751
39ACVR1B1.26694126
40MAPKAPK31.26461956
41BTK1.25529569
42CSK1.24795776
43IKBKB1.24351455
44CHUK1.19306954
45MARK21.19180194
46MAP2K31.18132223
47FRK1.18043527
48TEC1.15527083
49TIE11.13229812
50PIM11.08583044
51STK41.07645634
52TRPM71.07148847
53EPHA21.07043274
54CDK61.07043001
55HCK1.06682153
56RPS6KA41.06040134
57SYK1.04702785
58KDR1.03305791
59FLT30.99225829
60NEK90.98463990
61IRAK30.98093448
62LCK0.97795192
63JAK20.97265550
64IRAK40.97199503
65MARK30.95655266
66CAMK1G0.93711319
67MAP3K30.92400872
68MAP2K60.91635600
69CSF1R0.91488812
70MAPK70.89591607
71AKT30.89113221
72PTK2B0.88828614
73MAP3K70.87238603
74PDGFRA0.85128822
75PDGFRB0.84722488
76HIPK20.81920442
77TLK10.81724908
78PDPK10.79159105
79BLK0.78929648
80STK380.78520527
81TGFBR10.75691638
82MAP3K10.74169494
83RPS6KC10.73801996
84RPS6KL10.73801996
85MAP3K60.73568596
86PIK3CG0.73134720
87IRAK10.72441776
88STK30.71902401
89INSRR0.70461918
90MST40.69637356
91TAOK10.69008843
92PRKCH0.68902834
93DMPK0.68849968
94PDK10.68830387
95FES0.68805287
96RPS6KA20.68590568
97MAPK110.67932553
98NUAK10.67435579
99DYRK1B0.65771579
100ICK0.65345032
101CDK90.63448107
102SIK20.63253418
103LYN0.62416739
104WNK10.62338510
105SGK30.61867224
106CDK40.59081732
107PRKAA20.57363228
108ADRBK20.57103365
109PRKCQ0.55378245
110MTOR0.54835557
111MATK0.54789249
112RET0.54345441
113PIK3CA0.54203318
114MST1R0.52887626
115LATS10.52698988
116WNK40.52677086
117MAPK120.50843588
118BMX0.49380979
119MAP3K130.47074823
120CAMKK10.46962910
121PRKD10.46604436
122PRKD20.46177461
123SGK20.45996580
124EGFR0.44712246
125PTK20.44101404
126FGFR20.43342456
127ABL10.42323437
128MAP3K80.41847900
129RPS6KB20.41766760
130PIM20.38274601
131MELK0.37915821
132RPS6KA60.37037948
133PAK20.36048641
134MAPKAPK20.35483155
135IGF1R0.35094972

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.91384853
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.23887423
3Leishmaniasis_Homo sapiens_hsa051402.09933813
4Measles_Homo sapiens_hsa051622.05198753
5Hematopoietic cell lineage_Homo sapiens_hsa046401.92528243
6B cell receptor signaling pathway_Homo sapiens_hsa046621.91684269
7Autoimmune thyroid disease_Homo sapiens_hsa053201.88601317
8Osteoclast differentiation_Homo sapiens_hsa043801.86014685
9Caffeine metabolism_Homo sapiens_hsa002321.84957132
10Staphylococcus aureus infection_Homo sapiens_hsa051501.84867560
11Intestinal immune network for IgA production_Homo sapiens_hsa046721.80502301
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.78179765
13Antigen processing and presentation_Homo sapiens_hsa046121.67113147
14RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.62721372
15Toxoplasmosis_Homo sapiens_hsa051451.61761195
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.57221276
17Jak-STAT signaling pathway_Homo sapiens_hsa046301.52822175
18Asthma_Homo sapiens_hsa053101.50622289
19T cell receptor signaling pathway_Homo sapiens_hsa046601.49002272
20Chronic myeloid leukemia_Homo sapiens_hsa052201.46151186
21Malaria_Homo sapiens_hsa051441.43068645
22Leukocyte transendothelial migration_Homo sapiens_hsa046701.40364701
23ABC transporters_Homo sapiens_hsa020101.39075698
24Influenza A_Homo sapiens_hsa051641.36749056
25Herpes simplex infection_Homo sapiens_hsa051681.35540038
26Small cell lung cancer_Homo sapiens_hsa052221.34038415
27Acute myeloid leukemia_Homo sapiens_hsa052211.33707578
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.32172712
29Lysine degradation_Homo sapiens_hsa003101.31379489
30TNF signaling pathway_Homo sapiens_hsa046681.30850456
31AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.28159289
32Type I diabetes mellitus_Homo sapiens_hsa049401.26755354
33Complement and coagulation cascades_Homo sapiens_hsa046101.25402364
34Insulin resistance_Homo sapiens_hsa049311.24333795
35Hepatitis B_Homo sapiens_hsa051611.21962551
36Viral myocarditis_Homo sapiens_hsa054161.21693184
37Hepatitis C_Homo sapiens_hsa051601.15791370
38Pancreatic cancer_Homo sapiens_hsa052121.15440457
39Apoptosis_Homo sapiens_hsa042101.15177223
40NOD-like receptor signaling pathway_Homo sapiens_hsa046211.13899337
41Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.13702801
42Platelet activation_Homo sapiens_hsa046111.11138157
43Pertussis_Homo sapiens_hsa051331.04959711
44African trypanosomiasis_Homo sapiens_hsa051431.02978281
45Primary bile acid biosynthesis_Homo sapiens_hsa001201.02403970
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.00724619
47Fatty acid degradation_Homo sapiens_hsa000711.00356829
48Adipocytokine signaling pathway_Homo sapiens_hsa049200.99946964
49PPAR signaling pathway_Homo sapiens_hsa033200.97521836
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.96861594
51VEGF signaling pathway_Homo sapiens_hsa043700.96598115
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96462830
53Dorso-ventral axis formation_Homo sapiens_hsa043200.96062474
54Legionellosis_Homo sapiens_hsa051340.94954019
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.94225360
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.94153657
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.94130841
58Tuberculosis_Homo sapiens_hsa051520.92785500
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.92187238
60Prolactin signaling pathway_Homo sapiens_hsa049170.91180607
61Chemokine signaling pathway_Homo sapiens_hsa040620.89153330
62Tryptophan metabolism_Homo sapiens_hsa003800.88879779
63Pentose and glucuronate interconversions_Homo sapiens_hsa000400.88290203
64Allograft rejection_Homo sapiens_hsa053300.87822257
65Linoleic acid metabolism_Homo sapiens_hsa005910.85118073
66Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84714190
67Focal adhesion_Homo sapiens_hsa045100.84201253
68Graft-versus-host disease_Homo sapiens_hsa053320.82705807
69Adherens junction_Homo sapiens_hsa045200.82304746
70Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.82099986
71ECM-receptor interaction_Homo sapiens_hsa045120.80764102
72Amoebiasis_Homo sapiens_hsa051460.79534933
73Nitrogen metabolism_Homo sapiens_hsa009100.77112474
74Proteoglycans in cancer_Homo sapiens_hsa052050.76703837
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76690904
76Cyanoamino acid metabolism_Homo sapiens_hsa004600.75268134
77Viral carcinogenesis_Homo sapiens_hsa052030.74678653
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73367560
79Phospholipase D signaling pathway_Homo sapiens_hsa040720.73021626
80Prostate cancer_Homo sapiens_hsa052150.72484710
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72047775
82HTLV-I infection_Homo sapiens_hsa051660.71052434
83Choline metabolism in cancer_Homo sapiens_hsa052310.70291658
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69431172
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.69166294
86Lysosome_Homo sapiens_hsa041420.67509040
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.66470855
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65648379
89FoxO signaling pathway_Homo sapiens_hsa040680.65284045
90MicroRNAs in cancer_Homo sapiens_hsa052060.65228554
91Maturity onset diabetes of the young_Homo sapiens_hsa049500.64680752
92Arachidonic acid metabolism_Homo sapiens_hsa005900.63940979
93Shigellosis_Homo sapiens_hsa051310.63576116
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63443652
95Starch and sucrose metabolism_Homo sapiens_hsa005000.63396737
96Notch signaling pathway_Homo sapiens_hsa043300.63025797
97Non-small cell lung cancer_Homo sapiens_hsa052230.61754908
98Histidine metabolism_Homo sapiens_hsa003400.61597921
99GnRH signaling pathway_Homo sapiens_hsa049120.61048214
100Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60269451
101Other glycan degradation_Homo sapiens_hsa005110.60063492
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.59983177
103MAPK signaling pathway_Homo sapiens_hsa040100.59440505
104Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58718574
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58585446
106Renal cell carcinoma_Homo sapiens_hsa052110.57835601
107Bile secretion_Homo sapiens_hsa049760.56844971
108Ovarian steroidogenesis_Homo sapiens_hsa049130.55179738
109Glycerolipid metabolism_Homo sapiens_hsa005610.55113217
110Rheumatoid arthritis_Homo sapiens_hsa053230.55049782
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54712038
112Salmonella infection_Homo sapiens_hsa051320.52004708
113Selenocompound metabolism_Homo sapiens_hsa004500.51577915
114Bladder cancer_Homo sapiens_hsa052190.51350394
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.49367768
116Fat digestion and absorption_Homo sapiens_hsa049750.48992807
117Arginine biosynthesis_Homo sapiens_hsa002200.48961135
118Vitamin digestion and absorption_Homo sapiens_hsa049770.48516697
119Type II diabetes mellitus_Homo sapiens_hsa049300.47636410
120HIF-1 signaling pathway_Homo sapiens_hsa040660.44768531
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43699449
122Systemic lupus erythematosus_Homo sapiens_hsa053220.43479280
123p53 signaling pathway_Homo sapiens_hsa041150.42793626
124Estrogen signaling pathway_Homo sapiens_hsa049150.42490526
125Chemical carcinogenesis_Homo sapiens_hsa052040.42363056
126Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41619529
127Renin-angiotensin system_Homo sapiens_hsa046140.40714731
128Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40634516
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.40580630
130Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40221708
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.39366128
132Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38902587
133mTOR signaling pathway_Homo sapiens_hsa041500.38263219
134Ether lipid metabolism_Homo sapiens_hsa005650.38027145

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