TRMT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)5.45871977
2formation of translation preinitiation complex (GO:0001731)4.86220234
3ribosomal small subunit assembly (GO:0000028)4.82263261
4DNA strand elongation involved in DNA replication (GO:0006271)4.57221793
5DNA unwinding involved in DNA replication (GO:0006268)4.55331723
6DNA replication initiation (GO:0006270)4.48176118
7viral transcription (GO:0019083)4.47402289
8telomere maintenance via semi-conservative replication (GO:0032201)4.38836829
9translational termination (GO:0006415)4.36437957
10IMP biosynthetic process (GO:0006188)4.35773376
11folic acid-containing compound biosynthetic process (GO:0009396)4.35444212
12DNA deamination (GO:0045006)4.34323434
13DNA strand elongation (GO:0022616)4.34304379
14nucleobase biosynthetic process (GO:0046112)4.28864412
15translational elongation (GO:0006414)4.12225293
16ribosomal large subunit biogenesis (GO:0042273)4.10296781
17ribosome biogenesis (GO:0042254)4.06003524
18translational initiation (GO:0006413)3.97201948
19ribonucleoprotein complex biogenesis (GO:0022613)3.95747087
20ribosomal small subunit biogenesis (GO:0042274)3.94946840
21mitotic nuclear envelope disassembly (GO:0007077)3.87241504
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.83176507
23proline biosynthetic process (GO:0006561)3.75315785
24negative regulation of erythrocyte differentiation (GO:0045647)3.75158533
25telomere maintenance via recombination (GO:0000722)3.75106763
26protein localization to kinetochore (GO:0034501)3.74517818
27DNA replication-dependent nucleosome organization (GO:0034723)3.73758627
28DNA replication-dependent nucleosome assembly (GO:0006335)3.73758627
29purine nucleobase biosynthetic process (GO:0009113)3.72026240
30telomere maintenance via telomere lengthening (GO:0010833)3.70783449
31IMP metabolic process (GO:0046040)3.66294048
32pseudouridine synthesis (GO:0001522)3.62437571
33ribosome assembly (GO:0042255)3.61869256
34nuclear pore organization (GO:0006999)3.59757960
35membrane disassembly (GO:0030397)3.59738052
36nuclear envelope disassembly (GO:0051081)3.59738052
37rRNA processing (GO:0006364)3.58672744
38DNA replication checkpoint (GO:0000076)3.54781038
39viral mRNA export from host cell nucleus (GO:0046784)3.50273180
40negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.49038937
41rRNA metabolic process (GO:0016072)3.48283261
42mitotic metaphase plate congression (GO:0007080)3.48235874
43spliceosomal tri-snRNP complex assembly (GO:0000244)3.47391969
44regulation of translational fidelity (GO:0006450)3.47024341
45mitotic recombination (GO:0006312)3.46460538
46DNA duplex unwinding (GO:0032508)3.45630146
47DNA geometric change (GO:0032392)3.44526641
48SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.42974914
49pentose-phosphate shunt (GO:0006098)3.42846853
50cellular protein complex disassembly (GO:0043624)3.42662917
51Golgi transport vesicle coating (GO:0048200)3.38586337
52COPI coating of Golgi vesicle (GO:0048205)3.38586337
53protein maturation by protein folding (GO:0022417)3.37314710
54nucleotide-excision repair, DNA gap filling (GO:0006297)3.34966273
55viral life cycle (GO:0019058)3.33230196
56protein targeting to ER (GO:0045047)3.30090797
57regulation of nuclear cell cycle DNA replication (GO:0033262)3.28884171
58pre-miRNA processing (GO:0031054)3.28734473
59cotranslational protein targeting to membrane (GO:0006613)3.28610318
60negative regulation of RNA splicing (GO:0033119)3.25359646
61protein complex disassembly (GO:0043241)3.24698181
62regulation of mammary gland epithelial cell proliferation (GO:0033599)3.24280577
63peptidyl-arginine N-methylation (GO:0035246)3.23272863
64peptidyl-arginine methylation (GO:0018216)3.23272863
65spliceosomal snRNP assembly (GO:0000387)3.22960720
66regulation of gene silencing by RNA (GO:0060966)3.21450312
67regulation of posttranscriptional gene silencing (GO:0060147)3.21450312
68regulation of gene silencing by miRNA (GO:0060964)3.21450312
69protein localization to chromosome, centromeric region (GO:0071459)3.20755447
70deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.19975575
71heterochromatin organization (GO:0070828)3.19506552
72regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.19387255
73regulation of translational termination (GO:0006449)3.18756365
74rRNA transcription (GO:0009303)3.17636574
75nuclear pore complex assembly (GO:0051292)3.16775793
76establishment of protein localization to endoplasmic reticulum (GO:0072599)3.13453674
77UV protection (GO:0009650)3.13360850
78peptidyl-arginine omega-N-methylation (GO:0035247)3.13091391
79folic acid metabolic process (GO:0046655)3.11940277
80translesion synthesis (GO:0019985)3.11915875
81negative regulation of B cell apoptotic process (GO:0002903)3.11114058
82histone H4-K12 acetylation (GO:0043983)3.10328619
83macromolecular complex disassembly (GO:0032984)3.06006099
84nuclear-transcribed mRNA catabolic process (GO:0000956)3.05943340
85regulation of spindle organization (GO:0090224)3.05605157
86histone arginine methylation (GO:0034969)3.05538121
87protein localization to endoplasmic reticulum (GO:0070972)3.04920135
88cellular hyperosmotic response (GO:0071474)3.04507360
89regulation of histone H3-K9 methylation (GO:0051570)3.04441967
90somatic diversification of immune receptors via somatic mutation (GO:0002566)3.02837518
91somatic hypermutation of immunoglobulin genes (GO:0016446)3.02837518
92mitotic sister chromatid segregation (GO:0000070)3.00839067
933-UTR-mediated mRNA stabilization (GO:0070935)3.00625219
94NADPH regeneration (GO:0006740)3.00152197
95metaphase plate congression (GO:0051310)2.96836826
96histone H2A acetylation (GO:0043968)2.96801342
97negative regulation of mRNA metabolic process (GO:1903312)2.95522537
98rRNA modification (GO:0000154)2.95492712
99tRNA aminoacylation for protein translation (GO:0006418)2.93118388
100nucleotide salvage (GO:0043173)2.92483619
101RNA catabolic process (GO:0006401)2.91765135
102GDP-mannose metabolic process (GO:0019673)2.91659908
103establishment of integrated proviral latency (GO:0075713)2.91354247
104mRNA catabolic process (GO:0006402)2.89967080
105negative regulation of histone methylation (GO:0031061)2.89643212
106mitochondrial DNA metabolic process (GO:0032042)2.89573969
107negative regulation of mRNA processing (GO:0050686)2.89165265
108nuclear envelope organization (GO:0006998)2.86682318
109RNA splicing, via transesterification reactions (GO:0000375)2.86333327
110mitotic G1 DNA damage checkpoint (GO:0031571)2.86309005
111RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.86178211
112mRNA splicing, via spliceosome (GO:0000398)2.86178211
113telomere organization (GO:0032200)2.86015046
114telomere maintenance (GO:0000723)2.84589761
115base-excision repair (GO:0006284)2.83676663
116amino acid activation (GO:0043038)2.83170617
117tRNA aminoacylation (GO:0043039)2.83170617
118termination of RNA polymerase II transcription (GO:0006369)2.82672706
119nucleosome disassembly (GO:0006337)2.82339755
120protein-DNA complex disassembly (GO:0032986)2.82339755
121DNA topological change (GO:0006265)2.81856942
122translation (GO:0006412)2.81522994
123* ncRNA processing (GO:0034470)2.80652150
124nuclear envelope reassembly (GO:0031468)2.79990748
125mitotic nuclear envelope reassembly (GO:0007084)2.79990748
126dosage compensation (GO:0007549)2.79688269
127transcription-coupled nucleotide-excision repair (GO:0006283)2.79332772
128mitochondrial RNA metabolic process (GO:0000959)2.79266377
129mitotic chromosome condensation (GO:0007076)2.77920070
130negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.77119317
131pinocytosis (GO:0006907)2.77061366
132glucose catabolic process (GO:0006007)2.76793468
133transcription from mitochondrial promoter (GO:0006390)2.74536891
134apoptotic process involved in morphogenesis (GO:0060561)2.73052256
135snRNA metabolic process (GO:0016073)2.72937434
136establishment of viral latency (GO:0019043)2.70123846
137nucleobase-containing small molecule interconversion (GO:0015949)2.69873081
138negative regulation of cell size (GO:0045792)2.59537237
139pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.59269286
140pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.59075936
141protein complex localization (GO:0031503)2.57342229
142pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.55356308
143protein export from nucleus (GO:0006611)2.53786926
144cellular response to interleukin-4 (GO:0071353)2.51965091
145pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.50375141
146regulation of mitochondrial translation (GO:0070129)2.49583707
147ncRNA 3-end processing (GO:0043628)2.46229643
148pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.45046921
149mannose metabolic process (GO:0006013)2.44874576
150NIK/NF-kappaB signaling (GO:0038061)2.44652066
151snRNA processing (GO:0016180)2.43765204
152purine nucleotide salvage (GO:0032261)2.42310002
153positive regulation of B cell differentiation (GO:0045579)2.41176699
154pentose metabolic process (GO:0019321)2.40460319
155retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.40308483

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.47667302
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.27800592
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.67780293
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.44555082
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.30363251
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.07292500
7MYC_18358816_ChIP-ChIP_MESCs_Mouse2.80154853
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78399149
9* ETS1_20019798_ChIP-Seq_JURKAT_Human2.59259044
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.57926953
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.46902531
12MYC_22102868_ChIP-Seq_BL_Human2.40667366
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.37709673
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.35552950
15XRN2_22483619_ChIP-Seq_HELA_Human2.30180632
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.17474328
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.12803087
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.08378260
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.08314418
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.07522519
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.02140898
22CIITA_25753668_ChIP-Seq_RAJI_Human1.92937308
23SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.92409146
24CREB1_15753290_ChIP-ChIP_HEK293T_Human1.91669186
25NANOG_18555785_ChIP-Seq_MESCs_Mouse1.90995712
26* VDR_23849224_ChIP-Seq_CD4+_Human1.85445030
27THAP11_20581084_ChIP-Seq_MESCs_Mouse1.83293891
28LXR_22292898_ChIP-Seq_THP-1_Human1.82764938
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80254657
30ELK3_25401928_ChIP-Seq_HUVEC_Human1.80106263
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79697614
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.77079850
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.77010882
34* TTF2_22483619_ChIP-Seq_HELA_Human1.75813330
35* FOXP3_21729870_ChIP-Seq_TREG_Human1.75491524
36E2F1_21310950_ChIP-Seq_MCF-7_Human1.74776882
37ZNF263_19887448_ChIP-Seq_K562_Human1.73800159
38GABP_19822575_ChIP-Seq_HepG2_Human1.72922648
39KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.69367595
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.69347912
41DCP1A_22483619_ChIP-Seq_HELA_Human1.68455273
42NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.68036231
43CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.66322269
44PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.65961163
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.65305958
46YY1_21170310_ChIP-Seq_MESCs_Mouse1.64204722
47VDR_21846776_ChIP-Seq_THP-1_Human1.61513913
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60848037
49POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.58348415
50STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55062263
51AR_21909140_ChIP-Seq_LNCAP_Human1.49892114
52NOTCH1_21737748_ChIP-Seq_TLL_Human1.49132640
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.48287465
54KDM5A_27292631_Chip-Seq_BREAST_Human1.48101986
55TP63_17297297_ChIP-ChIP_HaCaT_Human1.47230416
56* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46869935
57TET1_21451524_ChIP-Seq_MESCs_Mouse1.46086927
58* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44771826
59* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.40962305
60NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.38272278
61P68_20966046_ChIP-Seq_HELA_Human1.38237103
62MAF_26560356_Chip-Seq_TH2_Human1.38018014
63RACK7_27058665_Chip-Seq_MCF-7_Human1.37344687
64DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.36794050
65KDM2B_26808549_Chip-Seq_SUP-B15_Human1.36755318
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36515001
67KDM2B_26808549_Chip-Seq_DND41_Human1.35837985
68THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.34750016
69ELF1_20517297_ChIP-Seq_JURKAT_Human1.33817998
70* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33758095
71PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31880400
72KLF4_18555785_ChIP-Seq_MESCs_Mouse1.30971804
73HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.30703235
74* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.30256376
75UTX_26944678_Chip-Seq_JUKART_Human1.30154396
76KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.24885143
77KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.24885143
78KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.24885143
79* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.23493955
80TFEB_21752829_ChIP-Seq_HELA_Human1.23216229
81RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23089086
82E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.22082401
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22038045
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.21712109
85NCOR1_26117541_ChIP-Seq_K562_Human1.21018633
86VDR_24763502_ChIP-Seq_THP-1_Human1.19813704
87RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.18575067
88ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18223577
89PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18123273
90CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17850133
91HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.17081631
92SA1_27219007_Chip-Seq_ERYTHROID_Human1.16359611
93ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.15341223
94BP1_19119308_ChIP-ChIP_Hs578T_Human1.15296559
95CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.14674248
96CTCF_27219007_Chip-Seq_ERYTHROID_Human1.14598579
97TP63_19390658_ChIP-ChIP_HaCaT_Human1.14227656
98RUNX1_22412390_ChIP-Seq_EML_Mouse1.13622194
99KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.13620176
100CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.13214040
101FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12953036
102GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12062176
103SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11789290
104KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10690340
105MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.10670803
106* SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.09839202
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.08118192
108MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.07225165
109* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06660467
110CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.05339320
111CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05171902
112PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05024633
113* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.04837574
114HOXB4_20404135_ChIP-ChIP_EML_Mouse1.03561316
115NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.03536494
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03419131
117BCOR_27268052_Chip-Seq_Bcells_Human1.03204678
118* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02253813
119BRD4_27068464_Chip-Seq_AML-cells_Mouse1.01877534
120SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01336828
121SRF_21415370_ChIP-Seq_HL-1_Mouse1.00757858
122CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00470135
123ELK1_19687146_ChIP-ChIP_HELA_Human0.99960789
124BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97380769
125CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95900594
126TCF3_18692474_ChIP-Seq_MEFs_Mouse0.95491730
127YY1_22570637_ChIP-Seq_MALME-3M_Human0.93491406
128* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91391489
129TCF7_22412390_ChIP-Seq_EML_Mouse0.90039786
130OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89667534
131TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.88995470
132NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.88254178
133ESR1_15608294_ChIP-ChIP_MCF-7_Human0.87873557
134MAF_26560356_Chip-Seq_TH1_Human0.86372829
135FOXP1_21924763_ChIP-Seq_HESCs_Human0.86272419
136PHF8_20622854_ChIP-Seq_HELA_Human0.84912516
137SPI1_23547873_ChIP-Seq_NB4_Human0.84622013

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.11271096
2MP0003111_abnormal_nucleus_morphology4.87570380
3MP0010094_abnormal_chromosome_stability4.48436288
4MP0004957_abnormal_blastocyst_morpholog4.08440660
5MP0003077_abnormal_cell_cycle3.93432960
6MP0008058_abnormal_DNA_repair3.43519696
7MP0008057_abnormal_DNA_replication3.27871288
8MP0002396_abnormal_hematopoietic_system3.13775449
9MP0005451_abnormal_body_composition2.93853107
10MP0008007_abnormal_cellular_replicative2.86458700
11MP0005058_abnormal_lysosome_morphology2.77205739
12MP0010352_gastrointestinal_tract_polyps2.45253693
13MP0001730_embryonic_growth_arrest2.39173197
14MP0008260_abnormal_autophagy2.35931327
15MP0003786_premature_aging2.29705076
16MP0008877_abnormal_DNA_methylation2.22662388
17MP0000350_abnormal_cell_proliferation2.21150241
18MP0008932_abnormal_embryonic_tissue2.17169622
19MP0003436_decreased_susceptibility_to2.14624721
20MP0004808_abnormal_hematopoietic_stem2.08792007
21MP0003123_paternal_imprinting2.01078563
22MP0000490_abnormal_crypts_of1.94746494
23MP0003172_abnormal_lysosome_physiology1.94263589
24MP0004185_abnormal_adipocyte_glucose1.92279414
25MP0002877_abnormal_melanocyte_morpholog1.88310564
26MP0010307_abnormal_tumor_latency1.82277475
27MP0001672_abnormal_embryogenesis/_devel1.76646560
28MP0005380_embryogenesis_phenotype1.76646560
29MP0001697_abnormal_embryo_size1.72156779
30MP0002080_prenatal_lethality1.71804130
31MP0000313_abnormal_cell_death1.66872875
32MP0001545_abnormal_hematopoietic_system1.66000625
33MP0005397_hematopoietic_system_phenotyp1.66000625
34MP0003763_abnormal_thymus_physiology1.63990727
35MP0005464_abnormal_platelet_physiology1.63695140
36MP0003191_abnormal_cellular_cholesterol1.63397830
37MP0005075_abnormal_melanosome_morpholog1.62080397
38MP0004133_heterotaxia1.61872545
39MP0002085_abnormal_embryonic_tissue1.60504040
40MP0002019_abnormal_tumor_incidence1.56683920
41MP0004197_abnormal_fetal_growth/weight/1.56530007
42MP0002084_abnormal_developmental_patter1.56309010
43MP0003984_embryonic_growth_retardation1.54400443
44MP0009278_abnormal_bone_marrow1.53477927
45MP0000678_abnormal_parathyroid_gland1.53263801
46MP0002796_impaired_skin_barrier1.53099910
47MP0002088_abnormal_embryonic_growth/wei1.51527559
48MP0000703_abnormal_thymus_morphology1.51141544
49MP0002086_abnormal_extraembryonic_tissu1.48025826
50MP0009333_abnormal_splenocyte_physiolog1.44036774
51MP0009840_abnormal_foam_cell1.40202597
52MP0004233_abnormal_muscle_weight1.40171745
53MP0006292_abnormal_olfactory_placode1.37112560
54MP0003303_peritoneal_inflammation1.34125817
55MP0002722_abnormal_immune_system1.33234082
56MP0002398_abnormal_bone_marrow1.33211355
57MP0002210_abnormal_sex_determination1.31684178
58MP0001661_extended_life_span1.30858431
59MP0004858_abnormal_nervous_system1.30687196
60MP0004947_skin_inflammation1.30164143
61MP0000689_abnormal_spleen_morphology1.30088354
62MP0003453_abnormal_keratinocyte_physiol1.27336228
63MP0006036_abnormal_mitochondrial_physio1.24808412
64MP0005000_abnormal_immune_tolerance1.24407327
65MP0003806_abnormal_nucleotide_metabolis1.23707175
66MP0005174_abnormal_tail_pigmentation1.21953515
67MP0000003_abnormal_adipose_tissue1.20015948
68MP0001145_abnormal_male_reproductive1.19318548
69MP0001835_abnormal_antigen_presentation1.17327804
70MP0001293_anophthalmia1.17083775
71MP0003567_abnormal_fetal_cardiomyocyte1.15888736
72MP0005076_abnormal_cell_differentiation1.15877737
73MP0002653_abnormal_ependyma_morphology1.12199143
74MP0001929_abnormal_gametogenesis1.11190535
75MP0000358_abnormal_cell_content/1.11041254
76MP0002723_abnormal_immune_serum1.08595990
77MP0010030_abnormal_orbit_morphology1.08432048
78MP0005666_abnormal_adipose_tissue1.08333426
79MP0003890_abnormal_embryonic-extraembry1.06533521
80MP0002160_abnormal_reproductive_system1.05199840
81MP0003119_abnormal_digestive_system1.04619206
82MP0005025_abnormal_response_to1.03987630
83MP0002060_abnormal_skin_morphology1.03092079
84MP0002429_abnormal_blood_cell1.02282701
85MP0002419_abnormal_innate_immunity1.02266959
86MP0002254_reproductive_system_inflammat1.00201581
87MP0008995_early_reproductive_senescence0.99857737
88MP0000371_diluted_coat_color0.99301056
89MP0003718_maternal_effect0.97277314
90MP0003283_abnormal_digestive_organ0.95303002
91MP0005375_adipose_tissue_phenotype0.95090067
92MP0000465_gastrointestinal_hemorrhage0.94655897
93MP0002405_respiratory_system_inflammati0.93525111
94MP0002148_abnormal_hypersensitivity_rea0.92037297
95MP0005384_cellular_phenotype0.92004880
96MP0000653_abnormal_sex_gland0.91686059
97MP0005023_abnormal_wound_healing0.88715172
98MP0005621_abnormal_cell_physiology0.88233029
99MP0000716_abnormal_immune_system0.87912636
100MP0002089_abnormal_postnatal_growth/wei0.87784190
101MP0002132_abnormal_respiratory_system0.84433336
102MP0002111_abnormal_tail_morphology0.83998137
103MP0000858_altered_metastatic_potential0.81576723
104MP0009931_abnormal_skin_appearance0.79635364
105MP0002075_abnormal_coat/hair_pigmentati0.79448125
106MP0000477_abnormal_intestine_morphology0.78674029
107MP0000685_abnormal_immune_system0.78411188
108MP0005330_cardiomyopathy0.78403304
109MP0001849_ear_inflammation0.78108553
110MP0001800_abnormal_humoral_immune0.77799209
111MP0003121_genomic_imprinting0.76820680
112MP0005389_reproductive_system_phenotype0.76659550
113MP0005387_immune_system_phenotype0.75777565
114MP0001790_abnormal_immune_system0.75777565
115MP0008770_decreased_survivor_rate0.75427799
116MP0005671_abnormal_response_to0.73898982
117MP0001915_intracranial_hemorrhage0.73232233
118MP0001216_abnormal_epidermal_layer0.73226266
119MP0000428_abnormal_craniofacial_morphol0.73203671
120MP0003941_abnormal_skin_development0.72044091
121MP0010234_abnormal_vibrissa_follicle0.71937318
122MP0001873_stomach_inflammation0.71085896
123MP0002269_muscular_atrophy0.70415316
124MP0003566_abnormal_cell_adhesion0.68206993
125MP0005501_abnormal_skin_physiology0.67957235
126MP0003705_abnormal_hypodermis_morpholog0.66043413
127MP0003698_abnormal_male_reproductive0.65039800
128MP0006035_abnormal_mitochondrial_morpho0.64041251
129MP0001348_abnormal_lacrimal_gland0.63577731
130MP0000537_abnormal_urethra_morphology0.62881417
131MP0001119_abnormal_female_reproductive0.62740705
132MP0001853_heart_inflammation0.61007357
133MP0002452_abnormal_antigen_presenting0.60901559
134MP0001919_abnormal_reproductive_system0.60479595
135MP0002092_abnormal_eye_morphology0.60330992
136MP0002420_abnormal_adaptive_immunity0.59526169
137MP0009672_abnormal_birth_weight0.58609770
138MP0001819_abnormal_immune_cell0.57887206
139MP0002095_abnormal_skin_pigmentation0.57833424
140MP0002161_abnormal_fertility/fecundity0.55393941

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.77561634
2Abnormality of cells of the erythroid lineage (HP:0012130)4.70583077
3Abnormal number of erythroid precursors (HP:0012131)4.44568538
4Birth length less than 3rd percentile (HP:0003561)4.39826377
5Selective tooth agenesis (HP:0001592)4.05363252
6Ependymoma (HP:0002888)3.81041347
7Oral leukoplakia (HP:0002745)3.49149802
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.48908178
9Aplastic anemia (HP:0001915)3.48135543
10Chromsome breakage (HP:0040012)3.41362867
11Ragged-red muscle fibers (HP:0003200)3.39698338
12Absent thumb (HP:0009777)3.32732001
13Breast hypoplasia (HP:0003187)3.29593552
14Rough bone trabeculation (HP:0100670)3.22986200
15Pallor (HP:0000980)3.20443444
16Supernumerary spleens (HP:0009799)3.05523784
17Colon cancer (HP:0003003)3.04101718
18Basal cell carcinoma (HP:0002671)2.98165587
19Medulloblastoma (HP:0002885)2.94114110
20Myelodysplasia (HP:0002863)2.93691529
21Macrocytic anemia (HP:0001972)2.92268074
22Patellar aplasia (HP:0006443)2.85774129
23Hypertensive crisis (HP:0100735)2.84231288
24Squamous cell carcinoma (HP:0002860)2.84050054
25Meckel diverticulum (HP:0002245)2.82205241
26Abnormality of DNA repair (HP:0003254)2.81245881
27Abnormality of the preputium (HP:0100587)2.81146572
28Degeneration of anterior horn cells (HP:0002398)2.80249203
29Abnormality of the anterior horn cell (HP:0006802)2.80249203
30Poikiloderma (HP:0001029)2.73884045
31Abnormality of the ileum (HP:0001549)2.72615295
32Centrally nucleated skeletal muscle fibers (HP:0003687)2.72163217
33Colitis (HP:0002583)2.70069976
34Agammaglobulinemia (HP:0004432)2.66804202
35Bone marrow hypocellularity (HP:0005528)2.66742200
36Progressive external ophthalmoplegia (HP:0000590)2.65594609
37Aplasia/Hypoplasia of the patella (HP:0006498)2.63732536
38Neoplasm of the pancreas (HP:0002894)2.61721359
39Carpal bone hypoplasia (HP:0001498)2.61383488
40Trismus (HP:0000211)2.60482185
41Microretrognathia (HP:0000308)2.60319609
42Premature graying of hair (HP:0002216)2.59301328
43Abnormality of chromosome stability (HP:0003220)2.58479207
44Abnormal number of incisors (HP:0011064)2.54819093
45Cellulitis (HP:0100658)2.52677298
46Recurrent viral infections (HP:0004429)2.52525186
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.52007476
48J-shaped sella turcica (HP:0002680)2.49499328
49Gastrointestinal inflammation (HP:0004386)2.48168211
50Abnormal gallbladder physiology (HP:0012438)2.47882037
51Cholecystitis (HP:0001082)2.47882037
52Thrombocytosis (HP:0001894)2.47016227
53Distal lower limb amyotrophy (HP:0008944)2.45097869
54Panhypogammaglobulinemia (HP:0003139)2.44248137
55Achilles tendon contracture (HP:0001771)2.41780273
56Duplicated collecting system (HP:0000081)2.39601438
57Tracheoesophageal fistula (HP:0002575)2.39226773
58Fatigue (HP:0012378)2.38917695
59Rhabdomyosarcoma (HP:0002859)2.38787880
60Progressive muscle weakness (HP:0003323)2.38608861
61Acute lymphatic leukemia (HP:0006721)2.38048816
62Agnosia (HP:0010524)2.38027656
63Glioma (HP:0009733)2.37008151
6411 pairs of ribs (HP:0000878)2.36363353
65Absent radius (HP:0003974)2.36253897
66Seborrheic dermatitis (HP:0001051)2.34642016
67Hyperacusis (HP:0010780)2.32599083
68Asplenia (HP:0001746)2.32366949
69Spinal muscular atrophy (HP:0007269)2.30770002
70Increased nuchal translucency (HP:0010880)2.30598725
71Premature ovarian failure (HP:0008209)2.29463769
72Small intestinal stenosis (HP:0012848)2.28153797
73Duodenal stenosis (HP:0100867)2.28153797
74Abnormality of the astrocytes (HP:0100707)2.27834520
75Astrocytoma (HP:0009592)2.27834520
76Impulsivity (HP:0100710)2.26717227
77Hepatosplenomegaly (HP:0001433)2.26372502
78Vertebral compression fractures (HP:0002953)2.23897511
79Abnormal trabecular bone morphology (HP:0100671)2.22758511
80Increased serum ferritin (HP:0003281)2.22448583
81Cellular immunodeficiency (HP:0005374)2.21005259
82Lymphoma (HP:0002665)2.20225031
83Abnormality of pyrimidine metabolism (HP:0004353)2.19929856
84Long palpebral fissure (HP:0000637)2.19520950
85Abnormality of the carotid arteries (HP:0005344)2.19520262
86Sloping forehead (HP:0000340)2.19369047
87Broad distal phalanx of finger (HP:0009836)2.18448490
88Abnormality of the lower motor neuron (HP:0002366)2.15834749
89Cerebral hypomyelination (HP:0006808)2.15660248
90Neoplasm of the oral cavity (HP:0100649)2.15449900
91Absent forearm bone (HP:0003953)2.15184773
92Aplasia involving forearm bones (HP:0009822)2.15184773
93Abnormality of reticulocytes (HP:0004312)2.11080838
94Horseshoe kidney (HP:0000085)2.10058113
95Neoplasm of striated muscle (HP:0009728)2.09908376
96Obstructive lung disease (HP:0006536)2.09244758
97Chronic obstructive pulmonary disease (HP:0006510)2.09244758
98Reticulocytosis (HP:0001923)2.09174478
99Abnormality of the Achilles tendon (HP:0005109)2.08147531
100Broad face (HP:0000283)2.07811826
101Biconcave vertebral bodies (HP:0004586)2.07679195
102Petechiae (HP:0000967)2.06203969
103Aplasia/Hypoplasia of the spleen (HP:0010451)2.06035419
104Abnormality of the renal collecting system (HP:0004742)2.05813615
105Prominent nose (HP:0000448)2.04925196
106Increased IgE level (HP:0003212)2.03354356
107Rhabdomyolysis (HP:0003201)2.03105494
108Abnormality of the duodenum (HP:0002246)2.02828279
109Abnormality of the thoracic spine (HP:0100711)2.01619282
110Pancytopenia (HP:0001876)2.01028670
111Truncus arteriosus (HP:0001660)2.00258602
112Inflammation of the large intestine (HP:0002037)1.99311932
113Microvesicular hepatic steatosis (HP:0001414)1.98524975
114Amaurosis fugax (HP:0100576)1.96398794
115Myopathic facies (HP:0002058)1.96041424
116Short thumb (HP:0009778)1.95608849
117Entropion (HP:0000621)1.95479267
118Ectopic kidney (HP:0000086)1.94122224
119Ureteral duplication (HP:0000073)1.93326871
120Testicular atrophy (HP:0000029)1.93252555
121Tongue fasciculations (HP:0001308)1.92010201
122IgM deficiency (HP:0002850)1.91110428
123Aplasia/Hypoplasia of the thymus (HP:0010515)1.91029269
124Insomnia (HP:0100785)1.90890536
125Abnormality of the labia minora (HP:0012880)1.90478453
126Increased neuronal autofluorescent lipopigment (HP:0002074)1.90245764
127Thoracic kyphosis (HP:0002942)1.90239401
128Increased cerebral lipofuscin (HP:0011813)1.89033076
129High pitched voice (HP:0001620)1.87903673
130Breech presentation (HP:0001623)1.87097869
131Cleft eyelid (HP:0000625)1.85167051
132Ulnar bowing (HP:0003031)1.85132940
133Proximal placement of thumb (HP:0009623)1.83788816
134Multiple enchondromatosis (HP:0005701)1.83537672
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.83256684
136Polygenic inheritance (HP:0010982)1.82668224
137Slender long bone (HP:0003100)1.82441256
138Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.81994619
139Aplasia/Hypoplasia of the sacrum (HP:0008517)1.81969012
140Cafe-au-lait spot (HP:0000957)1.80972543
141Abdominal situs inversus (HP:0003363)1.80707030
142Abnormality of abdominal situs (HP:0011620)1.80707030
143Clubbing of toes (HP:0100760)1.78003474
144Abnormality of the umbilical cord (HP:0010881)1.77973565
145Triphalangeal thumb (HP:0001199)1.77256184
146Abnormality of the columella (HP:0009929)1.76681618
147Orthostatic hypotension (HP:0001278)1.76537717
148Gastrointestinal dysmotility (HP:0002579)1.76072222
149Deep palmar crease (HP:0006191)1.75971588
150Easy fatigability (HP:0003388)1.74176240
151Premature skin wrinkling (HP:0100678)1.74023357
152Abnormality of the tricuspid valve (HP:0001702)1.74018592
153Increased connective tissue (HP:0009025)1.71355992
154Eczematoid dermatitis (HP:0000976)1.70620658
155Dysautonomia (HP:0002459)1.70373413
156Upper motor neuron abnormality (HP:0002127)1.68403808
157Generalized amyotrophy (HP:0003700)1.67859507
158Stridor (HP:0010307)1.66361471
159Granulocytopenia (HP:0001913)1.65901230
160Viral hepatitis (HP:0006562)1.65216983
161Villous atrophy (HP:0011473)1.64873395
162Abnormality of small intestinal villus morphology (HP:0011472)1.64873395
163Pointed chin (HP:0000307)1.64533149
164Death in infancy (HP:0001522)1.63121258
165Secondary amenorrhea (HP:0000869)1.62968187
166Difficulty climbing stairs (HP:0003551)1.61771330
167Distal lower limb muscle weakness (HP:0009053)1.59997819
168Abnormality of oral frenula (HP:0000190)1.59476225
169Lower limb amyotrophy (HP:0007210)1.58504721
170Abnormality of lateral ventricle (HP:0030047)1.58266236
171Ankyloglossia (HP:0010296)1.57866684
172Distal upper limb amyotrophy (HP:0007149)1.57063681
173Upper limb amyotrophy (HP:0009129)1.57063681
174Purpura (HP:0000979)1.56363595
175Mediastinal lymphadenopathy (HP:0100721)1.56263258
176Flared metaphyses (HP:0003015)1.55050896
177Increased muscle lipid content (HP:0009058)1.54873481
178Hyperthyroidism (HP:0000836)1.53759979
179Prolonged bleeding time (HP:0003010)1.53396232

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.17466221
2SMG13.69761646
3WEE13.56307381
4CDC73.16327359
5EEF2K3.15946105
6NEK22.77591120
7CDK122.61616515
8PRPF4B2.58378759
9TTK2.34595569
10RPS6KB22.31974477
11STK162.31090693
12EPHA22.31065922
13VRK22.19095529
14TSSK62.10934982
15MAP3K102.07059014
16SRPK12.02787130
17NEK11.98364451
18CDK71.84347467
19EIF2AK11.83485643
20MAP4K11.81850336
21NME21.76233081
22ATR1.73773186
23PASK1.73265358
24BRD41.71810412
25PLK11.69404452
26SIK11.56313799
27STK101.52144774
28DYRK31.49577960
29TLK11.49576922
30ZAK1.46819202
31PLK41.46584414
32TGFBR11.40800413
33PKN21.40472348
34ERN11.39704688
35MAP3K81.34425048
36CDK41.33686335
37FLT31.30523433
38ACVR1B1.28518836
39PAK41.27243840
40ARAF1.26746473
41AURKB1.23601961
42CHEK11.21094683
43MAP3K111.18445177
44RPS6KA41.17800378
45MAP3K131.17515486
46MAP2K31.16908514
47CHEK21.16536478
48TBK11.16256021
49IRAK31.12337763
50SCYL21.10091918
51TTN1.07371185
52AURKA1.07176179
53MST1R1.06567272
54BMX1.04381380
55MAP3K141.01568979
56MAPKAPK31.00489494
57PIM10.99529957
58TESK20.99271447
59GRK60.97192166
60ALK0.96696569
61FGFR40.95869755
62MAPK110.95170078
63VRK10.94367076
64NME10.91352150
65CDK20.90872804
66PLK30.87435200
67BRSK20.87037368
68PIM20.85321373
69MKNK10.85063508
70PRKD30.83699452
71BRSK10.83421506
72ZAP700.82773627
73IRAK20.82551322
74TRIB30.82224765
75LRRK20.81633138
76PRKCI0.81432259
77PDK20.81259422
78BLK0.81232617
79BCKDK0.80349452
80FES0.79991396
81MTOR0.78240492
82TYK20.76416321
83TAOK20.75856593
84SIK30.75315860
85STK40.74987739
86CDK60.74503736
87SIK20.73421801
88EIF2AK30.73108042
89ATM0.72735452
90BRAF0.72045806
91MKNK20.71736752
92RIPK40.71018660
93BTK0.65880707
94AKT20.65328044
95CDK90.63754875
96PBK0.63385479
97PNCK0.61833515
98PAK10.61687931
99KIT0.61508270
100CSNK2A20.61202507
101CDK80.59928663
102MAP3K10.59299554
103TNK20.58440390
104PTK60.58171024
105CDK10.52998459
106DAPK10.52429330
107EPHB10.50295661
108ICK0.49628903
109MAPK120.47886658
110KDR0.47649670
111RAF10.47535098
112ILK0.46119879
113IRAK40.45989934
114IKBKB0.45844301
115PRKD20.45548701
116CSNK2A10.44547905
117CSNK1E0.44428441
118MATK0.43129550
119RPS6KC10.42752316
120RPS6KL10.42752316
121TAOK10.41510184
122CSF1R0.40602843
123HCK0.39842424
124SYK0.38786447
125PDPK10.38140087
126ABL20.37824772
127PAK20.37710542
128MARK20.37410230
129CDK190.36754376
130YES10.36017337
131CLK10.33324503
132MAP2K60.33044597
133MAP3K30.32687564
134PRKDC0.32586837
135JAK30.31134686
136PDK40.29726415
137PDK30.29726415
138TESK10.26620976
139MAP2K20.26561108
140RPS6KA50.26040526
141RPS6KA10.25103062
142MAPK140.24731610

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.91204702
2Mismatch repair_Homo sapiens_hsa034304.25081297
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.81606348
4Ribosome_Homo sapiens_hsa030103.69451291
5One carbon pool by folate_Homo sapiens_hsa006703.33046688
6Spliceosome_Homo sapiens_hsa030403.30816592
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.17751087
8Base excision repair_Homo sapiens_hsa034103.16320260
9RNA transport_Homo sapiens_hsa030133.15698965
10Homologous recombination_Homo sapiens_hsa034402.87578767
11Nucleotide excision repair_Homo sapiens_hsa034202.74863559
12RNA polymerase_Homo sapiens_hsa030202.69095651
13Proteasome_Homo sapiens_hsa030502.54343510
14Cell cycle_Homo sapiens_hsa041102.31995865
15Pyrimidine metabolism_Homo sapiens_hsa002402.29492186
16Fanconi anemia pathway_Homo sapiens_hsa034602.24466416
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82796773
18mRNA surveillance pathway_Homo sapiens_hsa030151.82699349
19RNA degradation_Homo sapiens_hsa030181.67462347
20Non-homologous end-joining_Homo sapiens_hsa034501.66384598
21p53 signaling pathway_Homo sapiens_hsa041151.55672203
22Basal transcription factors_Homo sapiens_hsa030221.37974288
23Cyanoamino acid metabolism_Homo sapiens_hsa004601.28839802
24Epstein-Barr virus infection_Homo sapiens_hsa051691.21744607
25Purine metabolism_Homo sapiens_hsa002301.14263743
26Biosynthesis of amino acids_Homo sapiens_hsa012301.12897556
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.12797596
28Sulfur relay system_Homo sapiens_hsa041221.02591231
29Systemic lupus erythematosus_Homo sapiens_hsa053221.00699860
30Selenocompound metabolism_Homo sapiens_hsa004501.00496915
31Viral carcinogenesis_Homo sapiens_hsa052031.00104004
32Pentose phosphate pathway_Homo sapiens_hsa000300.96516172
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.95548158
34Herpes simplex infection_Homo sapiens_hsa051680.94236988
35Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91406672
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.88437148
37Pancreatic cancer_Homo sapiens_hsa052120.87358332
38VEGF signaling pathway_Homo sapiens_hsa043700.87317171
39Glycosaminoglycan degradation_Homo sapiens_hsa005310.87117384
40Notch signaling pathway_Homo sapiens_hsa043300.86843363
41HTLV-I infection_Homo sapiens_hsa051660.85779330
42Antigen processing and presentation_Homo sapiens_hsa046120.84268020
43Oocyte meiosis_Homo sapiens_hsa041140.80840688
44Primary immunodeficiency_Homo sapiens_hsa053400.79438976
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78364600
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.76400727
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73183893
48Fructose and mannose metabolism_Homo sapiens_hsa000510.70794069
49Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69274916
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.67002205
51Acute myeloid leukemia_Homo sapiens_hsa052210.62553981
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61056034
53Thyroid cancer_Homo sapiens_hsa052160.58810839
54Galactose metabolism_Homo sapiens_hsa000520.57941663
55Toll-like receptor signaling pathway_Homo sapiens_hsa046200.57851018
56Apoptosis_Homo sapiens_hsa042100.57783790
57Prion diseases_Homo sapiens_hsa050200.57247312
58Small cell lung cancer_Homo sapiens_hsa052220.55593833
59Viral myocarditis_Homo sapiens_hsa054160.55318053
60Leishmaniasis_Homo sapiens_hsa051400.54947485
61MicroRNAs in cancer_Homo sapiens_hsa052060.54496362
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.53604611
63Central carbon metabolism in cancer_Homo sapiens_hsa052300.52507257
64Osteoclast differentiation_Homo sapiens_hsa043800.52460055
65Lysine degradation_Homo sapiens_hsa003100.52015540
66Legionellosis_Homo sapiens_hsa051340.51816716
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51281936
68Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50095666
69Chronic myeloid leukemia_Homo sapiens_hsa052200.48972128
70NF-kappa B signaling pathway_Homo sapiens_hsa040640.48090622
71Lysosome_Homo sapiens_hsa041420.47581044
72Basal cell carcinoma_Homo sapiens_hsa052170.47121384
73Folate biosynthesis_Homo sapiens_hsa007900.46989524
74Colorectal cancer_Homo sapiens_hsa052100.46776286
75Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46712060
76Toxoplasmosis_Homo sapiens_hsa051450.44391751
77Shigellosis_Homo sapiens_hsa051310.44335622
78Salmonella infection_Homo sapiens_hsa051320.44223097
79N-Glycan biosynthesis_Homo sapiens_hsa005100.42522437
80Carbon metabolism_Homo sapiens_hsa012000.42046116
81HIF-1 signaling pathway_Homo sapiens_hsa040660.41415853
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41305479
83Measles_Homo sapiens_hsa051620.38581095
84Hepatitis C_Homo sapiens_hsa051600.38195503
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37108486
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36603379
87Pyruvate metabolism_Homo sapiens_hsa006200.36476989
88Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36454433
89TNF signaling pathway_Homo sapiens_hsa046680.35326336
90Hepatitis B_Homo sapiens_hsa051610.35047479
91Fatty acid elongation_Homo sapiens_hsa000620.34718164
92Glioma_Homo sapiens_hsa052140.34654003
93Bladder cancer_Homo sapiens_hsa052190.33676250
94Hippo signaling pathway_Homo sapiens_hsa043900.33671661
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33652115
96Alcoholism_Homo sapiens_hsa050340.32293126
97mTOR signaling pathway_Homo sapiens_hsa041500.32137331
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31750875
99Insulin signaling pathway_Homo sapiens_hsa049100.31024688
100Influenza A_Homo sapiens_hsa051640.30956357
101B cell receptor signaling pathway_Homo sapiens_hsa046620.30372932
102Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30260428
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.25298147
104Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.23775110
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.22393253
106Hedgehog signaling pathway_Homo sapiens_hsa043400.21501357
107Pathways in cancer_Homo sapiens_hsa052000.21349422
108RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.20136674
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19989878
110Thyroid hormone signaling pathway_Homo sapiens_hsa049190.18992540
111Non-small cell lung cancer_Homo sapiens_hsa052230.18923210
112NOD-like receptor signaling pathway_Homo sapiens_hsa046210.17753604
113TGF-beta signaling pathway_Homo sapiens_hsa043500.17237334
114Hematopoietic cell lineage_Homo sapiens_hsa046400.15802063
115Other glycan degradation_Homo sapiens_hsa005110.13683874
116Neurotrophin signaling pathway_Homo sapiens_hsa047220.13347709
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.13053046
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.12465704
119Glutathione metabolism_Homo sapiens_hsa004800.11646234
120Vitamin B6 metabolism_Homo sapiens_hsa007500.11603857
121T cell receptor signaling pathway_Homo sapiens_hsa046600.10809328
122Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.10361194

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