TRMT10B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)5.12388122
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.59388751
3behavioral response to nicotine (GO:0035095)4.53123227
4proteasome assembly (GO:0043248)4.49158460
5maturation of SSU-rRNA (GO:0030490)4.46076660
6L-fucose catabolic process (GO:0042355)4.45705608
7fucose catabolic process (GO:0019317)4.45705608
8L-fucose metabolic process (GO:0042354)4.45705608
9ribosomal small subunit assembly (GO:0000028)4.45596121
10energy coupled proton transport, down electrochemical gradient (GO:0015985)4.37927349
11ATP synthesis coupled proton transport (GO:0015986)4.37927349
12mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.03806992
13mitochondrial respiratory chain complex I assembly (GO:0032981)4.03806992
14NADH dehydrogenase complex assembly (GO:0010257)4.03806992
15chaperone-mediated protein transport (GO:0072321)3.97958564
16cullin deneddylation (GO:0010388)3.96222509
17kinetochore assembly (GO:0051382)3.95905149
18establishment of integrated proviral latency (GO:0075713)3.92012606
19kinetochore organization (GO:0051383)3.85887030
207-methylguanosine mRNA capping (GO:0006370)3.82366428
21protein deneddylation (GO:0000338)3.81603985
22protein complex biogenesis (GO:0070271)3.78239656
23viral transcription (GO:0019083)3.76331879
24mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.76014772
25RNA capping (GO:0036260)3.71734173
267-methylguanosine RNA capping (GO:0009452)3.71734173
27translational termination (GO:0006415)3.71272702
28response to pheromone (GO:0019236)3.70472338
29transcription elongation from RNA polymerase III promoter (GO:0006385)3.69696536
30termination of RNA polymerase III transcription (GO:0006386)3.69696536
31ribosomal large subunit biogenesis (GO:0042273)3.68655107
32indolalkylamine metabolic process (GO:0006586)3.65846778
33protein-cofactor linkage (GO:0018065)3.62847647
34negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.62751448
35platelet dense granule organization (GO:0060155)3.61195694
36transcription elongation from RNA polymerase I promoter (GO:0006362)3.60122486
37mitochondrial respiratory chain complex assembly (GO:0033108)3.59091997
38nucleobase biosynthetic process (GO:0046112)3.58563262
39cotranslational protein targeting to membrane (GO:0006613)3.57673061
40DNA deamination (GO:0045006)3.57596686
41ribonucleoprotein complex biogenesis (GO:0022613)3.57168696
42SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.54415325
43epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.52261131
44tryptophan catabolic process (GO:0006569)3.49949974
45indole-containing compound catabolic process (GO:0042436)3.49949974
46indolalkylamine catabolic process (GO:0046218)3.49949974
47CENP-A containing nucleosome assembly (GO:0034080)3.49317105
48protein targeting to ER (GO:0045047)3.48613138
49positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.45745654
50purine nucleobase biosynthetic process (GO:0009113)3.43456904
51preassembly of GPI anchor in ER membrane (GO:0016254)3.41957133
52detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.41871104
53mannosylation (GO:0097502)3.40510461
54chromatin remodeling at centromere (GO:0031055)3.39125092
55regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.38439551
56anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.38125485
57termination of RNA polymerase I transcription (GO:0006363)3.36769612
58cellular component biogenesis (GO:0044085)3.34507170
59regulation of cellular amino acid metabolic process (GO:0006521)3.33793635
60water-soluble vitamin biosynthetic process (GO:0042364)3.33591980
61translational elongation (GO:0006414)3.33454815
62protein localization to endoplasmic reticulum (GO:0070972)3.33077930
63negative regulation of ligase activity (GO:0051352)3.32926741
64negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.32926741
65regulation of mitochondrial translation (GO:0070129)3.31759574
66transcription from RNA polymerase I promoter (GO:0006360)3.31627358
67establishment of protein localization to endoplasmic reticulum (GO:0072599)3.30549006
68negative regulation of telomere maintenance (GO:0032205)3.29727293
69rRNA modification (GO:0000154)3.29267948
70epithelial cilium movement (GO:0003351)3.26380111
71cellular ketone body metabolic process (GO:0046950)3.25394705
72GTP biosynthetic process (GO:0006183)3.24145645
73cytochrome complex assembly (GO:0017004)3.24118215
74tryptophan metabolic process (GO:0006568)3.22743817
75DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.22299339
76respiratory chain complex IV assembly (GO:0008535)3.22200764
77translation (GO:0006412)3.21881081
78spliceosomal complex assembly (GO:0000245)3.20556739
79nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.20407356
80kynurenine metabolic process (GO:0070189)3.20135315
81exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.20126515
82respiratory electron transport chain (GO:0022904)3.19169992
83axoneme assembly (GO:0035082)3.19138033
84establishment of protein localization to mitochondrial membrane (GO:0090151)3.18298888
85cellular protein complex disassembly (GO:0043624)3.17415288
86piRNA metabolic process (GO:0034587)3.17303503
87signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.17285784
88intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.17285784
89protein targeting to mitochondrion (GO:0006626)3.17118043
90regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.16786223
91signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.16014038
92signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.16014038
93signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.16014038
94electron transport chain (GO:0022900)3.14508984
95transcription-coupled nucleotide-excision repair (GO:0006283)3.13336849
96detection of light stimulus involved in sensory perception (GO:0050962)3.13232738
97detection of light stimulus involved in visual perception (GO:0050908)3.13232738
98establishment of protein localization to mitochondrion (GO:0072655)3.12559262
99rRNA processing (GO:0006364)3.10997282
100establishment of viral latency (GO:0019043)3.10737618
101signal transduction involved in DNA damage checkpoint (GO:0072422)3.10432892
102signal transduction involved in DNA integrity checkpoint (GO:0072401)3.10432892
103RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.10181338
104tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.10181338
105transcription initiation from RNA polymerase I promoter (GO:0006361)3.10024139
106ketone body metabolic process (GO:1902224)3.09338667
107signal transduction involved in cell cycle checkpoint (GO:0072395)3.08017555
108translational initiation (GO:0006413)3.06944408
109spliceosomal snRNP assembly (GO:0000387)3.05698700
110guanosine-containing compound biosynthetic process (GO:1901070)3.04634826
111positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.03794634
112ribosome biogenesis (GO:0042254)3.00721008
113neural tube formation (GO:0001841)3.00416222
114rRNA metabolic process (GO:0016072)2.99371205
115histone exchange (GO:0043486)2.98228608
116intra-S DNA damage checkpoint (GO:0031573)2.98160342
117positive regulation of ligase activity (GO:0051351)2.97820226
118viral life cycle (GO:0019058)2.96750614
119regulation of nuclear cell cycle DNA replication (GO:0033262)2.96594278
120cytidine deamination (GO:0009972)2.95310092
121cytidine metabolic process (GO:0046087)2.95310092
122cytidine catabolic process (GO:0006216)2.95310092
123nonmotile primary cilium assembly (GO:0035058)2.94546101
124UTP biosynthetic process (GO:0006228)2.93794160
125microtubule polymerization or depolymerization (GO:0031109)2.92660981
126protein polyglutamylation (GO:0018095)2.91796133
127negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.91464548
128negative regulation of translation, ncRNA-mediated (GO:0040033)2.91464548
129regulation of translation, ncRNA-mediated (GO:0045974)2.91464548
130microtubule depolymerization (GO:0007019)2.89913578
131behavioral response to ethanol (GO:0048149)2.89415514
132nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.89234637
133DNA replication-independent nucleosome organization (GO:0034724)2.89169334
134DNA replication-independent nucleosome assembly (GO:0006336)2.89169334
135protein neddylation (GO:0045116)2.88610391
136maturation of 5.8S rRNA (GO:0000460)2.88270527
137ribosome assembly (GO:0042255)2.87885450
138regulation of cilium movement (GO:0003352)2.86914411
139transcription elongation from RNA polymerase II promoter (GO:0006368)2.85734515
140protein localization to mitochondrion (GO:0070585)2.84734881
141positive regulation of defense response to virus by host (GO:0002230)2.80714312
142somite development (GO:0061053)2.78652880
143inositol phosphate catabolic process (GO:0071545)2.77813347
144GPI anchor metabolic process (GO:0006505)2.76068323
145cilium morphogenesis (GO:0060271)2.74885691
146negative regulation of mast cell activation (GO:0033004)2.72845225
147DNA demethylation (GO:0080111)2.72294109
148cilium movement (GO:0003341)2.71461199
149L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.71169225
150photoreceptor cell maintenance (GO:0045494)2.69208082
151ubiquinone biosynthetic process (GO:0006744)2.68610587
152dopamine transport (GO:0015872)2.67957916
153protein localization to cilium (GO:0061512)2.67151506
154indole-containing compound metabolic process (GO:0042430)2.64864769
155negative regulation of DNA-dependent DNA replication (GO:2000104)2.60704216
156pyrimidine ribonucleoside catabolic process (GO:0046133)2.59521310
157regulation of glucokinase activity (GO:0033131)2.58898057
158regulation of hexokinase activity (GO:1903299)2.58898057
159cilium organization (GO:0044782)2.58593398
160reciprocal DNA recombination (GO:0035825)2.58034386
161reciprocal meiotic recombination (GO:0007131)2.58034386
162recombinational repair (GO:0000725)2.57208435
163double-strand break repair via homologous recombination (GO:0000724)2.56829937
164regulation of action potential (GO:0098900)2.56139921
165replication fork processing (GO:0031297)2.52734791
166DNA methylation involved in gamete generation (GO:0043046)2.51176795
167cilium assembly (GO:0042384)2.49439568
168cellular biogenic amine catabolic process (GO:0042402)2.49323367
169amine catabolic process (GO:0009310)2.49323367
170cornea development in camera-type eye (GO:0061303)2.48479998
171phosphorylated carbohydrate dephosphorylation (GO:0046838)2.47374461
172inositol phosphate dephosphorylation (GO:0046855)2.47374461
173centriole replication (GO:0007099)2.47147519
174neuronal action potential (GO:0019228)2.47101596
175photoreceptor cell development (GO:0042461)2.45136327
176amino acid salvage (GO:0043102)2.44894737
177L-methionine salvage (GO:0071267)2.44894737
178L-methionine biosynthetic process (GO:0071265)2.44894737
179ubiquinone metabolic process (GO:0006743)2.43744443
180positive regulation of oligodendrocyte differentiation (GO:0048714)2.43657174
181pseudouridine synthesis (GO:0001522)2.43267387
182positive regulation of fatty acid transport (GO:2000193)2.42475934
183adaptation of signaling pathway (GO:0023058)2.41331381
184S-adenosylmethionine metabolic process (GO:0046500)2.41013041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.67508619
2EST1_17652178_ChIP-ChIP_JURKAT_Human3.99660788
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.96968151
4ZNF274_21170338_ChIP-Seq_K562_Hela3.94024432
5E2F7_22180533_ChIP-Seq_HELA_Human3.92643349
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.85368748
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.64019726
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.52404751
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.34255651
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.31518193
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.22125925
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.09716790
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.05200661
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97362847
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.80040431
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.53853672
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.48763392
18HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.41274187
19VDR_23849224_ChIP-Seq_CD4+_Human2.39242471
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.36754786
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.33396383
22MYC_18358816_ChIP-ChIP_MESCs_Mouse2.32999854
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.23088934
24THAP11_20581084_ChIP-Seq_MESCs_Mouse2.20392182
25MYC_19030024_ChIP-ChIP_MESCs_Mouse2.16128234
26FOXP3_21729870_ChIP-Seq_TREG_Human2.10604177
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.01293052
28ELK1_19687146_ChIP-ChIP_HELA_Human2.00483403
29PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92014411
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.90741969
31P300_19829295_ChIP-Seq_ESCs_Human1.89473059
32FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.85235594
33EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.84579557
34SRF_21415370_ChIP-Seq_HL-1_Mouse1.84444949
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.83034837
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80998708
37XRN2_22483619_ChIP-Seq_HELA_Human1.79362302
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78373367
39DCP1A_22483619_ChIP-Seq_HELA_Human1.77808930
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75857865
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72492207
42TTF2_22483619_ChIP-Seq_HELA_Human1.71144388
43IGF1R_20145208_ChIP-Seq_DFB_Human1.70687109
44EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.69839499
45FUS_26573619_Chip-Seq_HEK293_Human1.67720308
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67685292
47GABP_19822575_ChIP-Seq_HepG2_Human1.67625367
48TP53_22573176_ChIP-Seq_HFKS_Human1.67014132
49NELFA_20434984_ChIP-Seq_ESCs_Mouse1.66485252
50IRF1_19129219_ChIP-ChIP_H3396_Human1.66269644
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60990891
52VDR_22108803_ChIP-Seq_LS180_Human1.60435686
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.60419857
54FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60392617
55MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.58286165
56POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.57090169
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46365128
58BCAT_22108803_ChIP-Seq_LS180_Human1.45652753
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44802979
60EWS_26573619_Chip-Seq_HEK293_Human1.41227116
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41008221
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40681576
63IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37742094
64CBP_20019798_ChIP-Seq_JUKART_Human1.37742094
65MYC_18940864_ChIP-ChIP_HL60_Human1.37577182
66SOX2_19829295_ChIP-Seq_ESCs_Human1.37353129
67NANOG_19829295_ChIP-Seq_ESCs_Human1.37353129
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.37340685
69SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35973019
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32757579
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32757579
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32492267
73STAT3_23295773_ChIP-Seq_U87_Human1.32146031
74PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31598395
75AR_21909140_ChIP-Seq_LNCAP_Human1.31452046
76ZFP57_27257070_Chip-Seq_ESCs_Mouse1.31107556
77FOXA1_27270436_Chip-Seq_PROSTATE_Human1.30016359
78FOXA1_25329375_ChIP-Seq_VCAP_Human1.30016359
79AR_25329375_ChIP-Seq_VCAP_Human1.29477655
80PCGF2_27294783_Chip-Seq_ESCs_Mouse1.27685810
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27528674
82SMAD4_21799915_ChIP-Seq_A2780_Human1.27011802
83MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26859584
84ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.26686630
85PIAS1_25552417_ChIP-Seq_VCAP_Human1.26372875
86GBX2_23144817_ChIP-Seq_PC3_Human1.26365462
87EZH2_27294783_Chip-Seq_NPCs_Mouse1.26232304
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25989787
89TCF4_23295773_ChIP-Seq_U87_Human1.24663149
90FLI1_27457419_Chip-Seq_LIVER_Mouse1.24610877
91TAF15_26573619_Chip-Seq_HEK293_Human1.22813973
92RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22596257
93PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22150799
94GATA3_21878914_ChIP-Seq_MCF-7_Human1.21140357
95SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.21109595
96NR3C1_21868756_ChIP-Seq_MCF10A_Human1.20556533
97ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19739162
98TCF4_22108803_ChIP-Seq_LS180_Human1.17118395
99FOXA1_21572438_ChIP-Seq_LNCaP_Human1.16502550
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.16484636
101AR_20517297_ChIP-Seq_VCAP_Human1.16127711
102BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15553418
103SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14441373
104EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.13265642
105SALL1_21062744_ChIP-ChIP_HESCs_Human1.12812577
106NCOR_22424771_ChIP-Seq_293T_Human1.11643285
107POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11554204
108SMAD3_21741376_ChIP-Seq_EPCs_Human1.10737000
109HOXB7_26014856_ChIP-Seq_BT474_Human1.08664806
110NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.07593622
111TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06815904
112RUNX2_22187159_ChIP-Seq_PCA_Human1.06345690
113CBX2_27304074_Chip-Seq_ESCs_Mouse1.05438076
114KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.05372825
115POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05157766
116EZH2_22144423_ChIP-Seq_EOC_Human1.03599555
117PRDM14_20953172_ChIP-Seq_ESCs_Human1.03333549
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03174885
119CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03147585
120KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02692722
121NANOG_18555785_ChIP-Seq_MESCs_Mouse1.02658066
122CRX_20693478_ChIP-Seq_RETINA_Mouse1.02414754
123REST_21632747_ChIP-Seq_MESCs_Mouse1.01584495
124EGR1_23403033_ChIP-Seq_LIVER_Mouse1.00944597
125GATA3_26560356_Chip-Seq_TH2_Human1.00185842
126AR_21572438_ChIP-Seq_LNCaP_Human0.99844855
127FLI1_21867929_ChIP-Seq_TH2_Mouse0.99512653
128P53_22387025_ChIP-Seq_ESCs_Mouse0.99206255
129EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97743757
130E2F1_21310950_ChIP-Seq_MCF-7_Human0.96589424
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96404113
132OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96076831
133NANOG_18555785_Chip-Seq_ESCs_Mouse0.95391473
134SMAD4_21741376_ChIP-Seq_EPCs_Human0.94163291
135FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.93352612
136KDM5A_27292631_Chip-Seq_BREAST_Human0.92063190
137ELK1_22589737_ChIP-Seq_MCF10A_Human0.91683620
138ERG_20887958_ChIP-Seq_HPC-7_Mouse0.90912805
139TP63_19390658_ChIP-ChIP_HaCaT_Human0.90723184
140SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90437185
141HTT_18923047_ChIP-ChIP_STHdh_Human0.89832942
142CIITA_25753668_ChIP-Seq_RAJI_Human0.89637012
143BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88467193
144NOTCH1_21737748_ChIP-Seq_TLL_Human0.87718259
145SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.85971978
146POU5F1_16153702_ChIP-ChIP_HESCs_Human0.85562974
147CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.84779100
148KAP1_22055183_ChIP-Seq_ESCs_Mouse0.84653763
149CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.84315856
150ER_23166858_ChIP-Seq_MCF-7_Human0.84133615
151CTBP1_25329375_ChIP-Seq_LNCAP_Human0.82549185
152RNF2_27304074_Chip-Seq_NSC_Mouse0.82205535
153ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81395146
154SOX17_20123909_ChIP-Seq_XEN_Mouse0.79728224
155CTBP2_25329375_ChIP-Seq_LNCAP_Human0.78943216
156FOXM1_23109430_ChIP-Seq_U2OS_Human0.77980261
157NFE2_27457419_Chip-Seq_LIVER_Mouse0.77426927
158TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.77325962
159GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76552714
160RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.74736579

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.53055189
2MP0001188_hyperpigmentation3.52203042
3MP0003693_abnormal_embryo_hatching3.40264305
4MP0000569_abnormal_digit_pigmentation2.97361584
5MP0003195_calcinosis2.91899376
6MP0010094_abnormal_chromosome_stability2.86835899
7MP0008877_abnormal_DNA_methylation2.79227749
8MP0001529_abnormal_vocalization2.78186328
9MP0004957_abnormal_blastocyst_morpholog2.68195487
10MP0008058_abnormal_DNA_repair2.68009474
11MP0003111_abnormal_nucleus_morphology2.61302181
12MP0008057_abnormal_DNA_replication2.55426109
13MP0003880_abnormal_central_pattern2.54800744
14MP0005645_abnormal_hypothalamus_physiol2.32385447
15MP0002735_abnormal_chemical_nociception2.26803587
16MP0003718_maternal_effect2.26218956
17MP0001905_abnormal_dopamine_level2.20312339
18MP0003077_abnormal_cell_cycle2.18795870
19MP0002736_abnormal_nociception_after2.13864382
20MP0001968_abnormal_touch/_nociception2.04483116
21MP0004147_increased_porphyrin_level2.03319165
22MP0002734_abnormal_mechanical_nocicepti1.99522256
23MP0001986_abnormal_taste_sensitivity1.96337834
24MP0008875_abnormal_xenobiotic_pharmacok1.89908767
25MP0005174_abnormal_tail_pigmentation1.83357742
26MP0003786_premature_aging1.77901917
27MP0008932_abnormal_embryonic_tissue1.76935978
28MP0003123_paternal_imprinting1.76923652
29MP0004270_analgesia1.75831489
30MP0005253_abnormal_eye_physiology1.75157590
31MP0006292_abnormal_olfactory_placode1.74488031
32MP0003646_muscle_fatigue1.74226196
33MP0002837_dystrophic_cardiac_calcinosis1.70189504
34MP0006036_abnormal_mitochondrial_physio1.67987344
35MP0002638_abnormal_pupillary_reflex1.66535175
36MP0008007_abnormal_cellular_replicative1.62857088
37MP0005409_darkened_coat_color1.62566992
38MP0005084_abnormal_gallbladder_morpholo1.61326143
39MP0003121_genomic_imprinting1.60620770
40MP0002163_abnormal_gland_morphology1.58033599
41MP0002272_abnormal_nervous_system1.54172405
42MP0000427_abnormal_hair_cycle1.52606155
43MP0006276_abnormal_autonomic_nervous1.48682956
44MP0001984_abnormal_olfaction1.47761527
45MP0005410_abnormal_fertilization1.47261456
46MP0008995_early_reproductive_senescence1.47219840
47MP0000631_abnormal_neuroendocrine_gland1.46985937
48MP0004885_abnormal_endolymph1.46798326
49MP0003950_abnormal_plasma_membrane1.45812769
50MP0001929_abnormal_gametogenesis1.45317719
51MP0003122_maternal_imprinting1.44623715
52MP0009745_abnormal_behavioral_response1.42349595
53MP0003787_abnormal_imprinting1.41549989
54MP0004142_abnormal_muscle_tone1.41511990
55MP0005379_endocrine/exocrine_gland_phen1.41387519
56MP0003011_delayed_dark_adaptation1.39378455
57MP0004043_abnormal_pH_regulation1.39180381
58MP0002095_abnormal_skin_pigmentation1.37543187
59MP0002234_abnormal_pharynx_morphology1.37095648
60MP0002928_abnormal_bile_duct1.36215853
61MP0001501_abnormal_sleep_pattern1.33730074
62MP0002210_abnormal_sex_determination1.30817898
63MP0001440_abnormal_grooming_behavior1.29901409
64MP0002733_abnormal_thermal_nociception1.29207483
65MP0009046_muscle_twitch1.28440381
66MP0003698_abnormal_male_reproductive1.28007489
67MP0002064_seizures1.27283354
68MP0002572_abnormal_emotion/affect_behav1.26778797
69MP0001970_abnormal_pain_threshold1.25686043
70MP0006035_abnormal_mitochondrial_morpho1.21389242
71MP0000372_irregular_coat_pigmentation1.19070724
72MP0008260_abnormal_autophagy1.18261503
73MP0001485_abnormal_pinna_reflex1.18045390
74MP0002160_abnormal_reproductive_system1.16437626
75MP0002876_abnormal_thyroid_physiology1.15681626
76MP0006072_abnormal_retinal_apoptosis1.14740331
77MP0002938_white_spotting1.14527348
78MP0003806_abnormal_nucleotide_metabolis1.13149859
79MP0000653_abnormal_sex_gland1.11677501
80MP0001145_abnormal_male_reproductive1.11531638
81MP0002067_abnormal_sensory_capabilities1.11446494
82MP0003635_abnormal_synaptic_transmissio1.10975947
83MP0001486_abnormal_startle_reflex1.10542562
84MP0005671_abnormal_response_to1.06510241
85MP0002822_catalepsy1.05429190
86MP0002751_abnormal_autonomic_nervous1.05373620
87MP0009697_abnormal_copulation1.04009495
88MP0004924_abnormal_behavior1.00802492
89MP0005386_behavior/neurological_phenoty1.00802492
90MP0002102_abnormal_ear_morphology1.00682852
91MP0005408_hypopigmentation0.98306420
92MP0005389_reproductive_system_phenotype0.97764161
93MP0000383_abnormal_hair_follicle0.97595964
94MP0005423_abnormal_somatic_nervous0.96540147
95MP0001324_abnormal_eye_pigmentation0.96422785
96MP0002132_abnormal_respiratory_system0.96406212
97MP0005195_abnormal_posterior_eye0.96291616
98MP0002063_abnormal_learning/memory/cond0.95569175
99MP0005377_hearing/vestibular/ear_phenot0.95412089
100MP0003878_abnormal_ear_physiology0.95412089
101MP0001764_abnormal_homeostasis0.92422280
102MP0003315_abnormal_perineum_morphology0.92410234
103MP0001963_abnormal_hearing_physiology0.91799014
104MP0005075_abnormal_melanosome_morpholog0.89729321
105MP0003136_yellow_coat_color0.89175641
106MP0002184_abnormal_innervation0.88739133
107MP0003252_abnormal_bile_duct0.88339520
108MP0001730_embryonic_growth_arrest0.87379663
109MP0003186_abnormal_redox_activity0.86528930
110MP0002277_abnormal_respiratory_mucosa0.86439170
111MP0010386_abnormal_urinary_bladder0.84473651
112MP0002161_abnormal_fertility/fecundity0.83801731
113MP0005171_absent_coat_pigmentation0.81963869
114MP0001293_anophthalmia0.80127555
115MP0000778_abnormal_nervous_system0.78420207
116MP0003879_abnormal_hair_cell0.78154496
117MP0002557_abnormal_social/conspecific_i0.77695723
118MP0000015_abnormal_ear_pigmentation0.77395382
119MP0002138_abnormal_hepatobiliary_system0.77096509
120MP0000313_abnormal_cell_death0.76830049
121MP0000647_abnormal_sebaceous_gland0.75881713
122MP0002653_abnormal_ependyma_morphology0.75489292
123MP0005646_abnormal_pituitary_gland0.75184266
124MP0004133_heterotaxia0.74067169
125MP0009764_decreased_sensitivity_to0.73612662
126MP0002229_neurodegeneration0.72096311
127MP0002752_abnormal_somatic_nervous0.71510910
128MP0002693_abnormal_pancreas_physiology0.71434231
129MP0005551_abnormal_eye_electrophysiolog0.71383206
130MP0004742_abnormal_vestibular_system0.71347159
131MP0008872_abnormal_physiological_respon0.71115839
132MP0001919_abnormal_reproductive_system0.69463486
133MP0001727_abnormal_embryo_implantation0.68783929
134MP0004145_abnormal_muscle_electrophysio0.68766913
135MP0000026_abnormal_inner_ear0.67624260
136MP0008789_abnormal_olfactory_epithelium0.67125283
137MP0000230_abnormal_systemic_arterial0.66484703

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.52096567
2Abnormality of midbrain morphology (HP:0002418)4.14372041
3Molar tooth sign on MRI (HP:0002419)4.14372041
4Mitochondrial inheritance (HP:0001427)4.09887711
5Abnormal mitochondria in muscle tissue (HP:0008316)4.04314999
6Increased CSF lactate (HP:0002490)4.02423889
7True hermaphroditism (HP:0010459)4.00170333
8Progressive macrocephaly (HP:0004481)3.88321085
9Hepatocellular necrosis (HP:0001404)3.84025384
10Nephronophthisis (HP:0000090)3.72340940
11Congenital stationary night blindness (HP:0007642)3.71099612
12Acute encephalopathy (HP:0006846)3.61293913
13Birth length less than 3rd percentile (HP:0003561)3.53958564
14Type II lissencephaly (HP:0007260)3.34116070
15Abnormality of glycolysis (HP:0004366)3.29624463
16Increased serum pyruvate (HP:0003542)3.29624463
17Reticulocytopenia (HP:0001896)3.28040982
18Abnormal hair whorl (HP:0010721)3.23880981
19Abnormality of the renal cortex (HP:0011035)3.20730641
20Abnormality of the renal medulla (HP:0100957)3.19772028
21Chronic hepatic failure (HP:0100626)3.17938352
22Hepatic necrosis (HP:0002605)3.17433873
23Increased hepatocellular lipid droplets (HP:0006565)3.06367797
24Breast hypoplasia (HP:0003187)3.02013545
25Focal motor seizures (HP:0011153)3.00007868
26Increased serum lactate (HP:0002151)2.98238337
27Cerebral hypomyelination (HP:0006808)2.94662685
28Decreased activity of mitochondrial respiratory chain (HP:0008972)2.92155672
29Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.92155672
30Medial flaring of the eyebrow (HP:0010747)2.89752830
31Abnormality of cells of the erythroid lineage (HP:0012130)2.81296282
323-Methylglutaconic aciduria (HP:0003535)2.79799744
33Facial cleft (HP:0002006)2.76782908
34CNS hypomyelination (HP:0003429)2.76329886
35Attenuation of retinal blood vessels (HP:0007843)2.76072265
36Cystic liver disease (HP:0006706)2.73806133
37Abolished electroretinogram (ERG) (HP:0000550)2.70915607
38Abnormal drinking behavior (HP:0030082)2.70313807
39Polydipsia (HP:0001959)2.70313807
40Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.69640651
41Absent thumb (HP:0009777)2.69347176
42Leukodystrophy (HP:0002415)2.64544919
43Lipid accumulation in hepatocytes (HP:0006561)2.61966313
44Sensory axonal neuropathy (HP:0003390)2.61964222
45Cerebellar dysplasia (HP:0007033)2.61565102
46Macrocytic anemia (HP:0001972)2.60206825
47Degeneration of the lateral corticospinal tracts (HP:0002314)2.58175417
48Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.58175417
49Microvesicular hepatic steatosis (HP:0001414)2.52312655
50Renal cortical cysts (HP:0000803)2.52038757
51Abnormal number of erythroid precursors (HP:0012131)2.51393718
52Abnormality of the anterior horn cell (HP:0006802)2.51110309
53Degeneration of anterior horn cells (HP:0002398)2.51110309
54Bile duct proliferation (HP:0001408)2.49528209
55Abnormal biliary tract physiology (HP:0012439)2.49528209
56Tubular atrophy (HP:0000092)2.48699175
57Optic disc pallor (HP:0000543)2.48376513
58Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.46805230
59Respiratory failure (HP:0002878)2.45539825
60Pancreatic fibrosis (HP:0100732)2.45111488
61Renal Fanconi syndrome (HP:0001994)2.41168029
62Sclerocornea (HP:0000647)2.38305746
63Lissencephaly (HP:0001339)2.38046257
64Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.36577327
65Inability to walk (HP:0002540)2.34711296
66Parakeratosis (HP:0001036)2.31924830
67Lactic acidosis (HP:0003128)2.31345359
68Hypothermia (HP:0002045)2.30124226
69Supernumerary spleens (HP:0009799)2.25951231
70Pendular nystagmus (HP:0012043)2.24002882
71Abnormal rod and cone electroretinograms (HP:0008323)2.22362151
72Short tibia (HP:0005736)2.22303976
73Median cleft lip (HP:0000161)2.20376697
74Aplasia/Hypoplasia of the tongue (HP:0010295)2.19002201
75Decreased central vision (HP:0007663)2.18435007
76Chromosomal breakage induced by crosslinking agents (HP:0003221)2.18207057
77Chromsome breakage (HP:0040012)2.18115373
78Exercise intolerance (HP:0003546)2.17460674
79Abnormality of the labia minora (HP:0012880)2.16880733
80Gait imbalance (HP:0002141)2.15796489
81Methylmalonic acidemia (HP:0002912)2.15584841
82Abnormality of the pons (HP:0007361)2.15035082
83Congenital hepatic fibrosis (HP:0002612)2.14735713
84Atonic seizures (HP:0010819)2.13281111
85Aplasia/Hypoplasia of the tibia (HP:0005772)2.12790882
86Progressive inability to walk (HP:0002505)2.11115331
87Congenital, generalized hypertrichosis (HP:0004540)2.08688992
88Large for gestational age (HP:0001520)2.08587908
89Hypoplasia of the pons (HP:0012110)2.08427407
90Congenital primary aphakia (HP:0007707)2.08167837
91Gaze-evoked nystagmus (HP:0000640)2.07885448
92Pallor (HP:0000980)2.07257884
93Duplicated collecting system (HP:0000081)2.06535560
94Dynein arm defect of respiratory motile cilia (HP:0012255)2.06246241
95Absent/shortened dynein arms (HP:0200106)2.06246241
96Polyuria (HP:0000103)2.05091521
97Anencephaly (HP:0002323)2.03425276
98Retinal dysplasia (HP:0007973)2.03375052
99Cerebral edema (HP:0002181)2.02633063
100Male pseudohermaphroditism (HP:0000037)2.01983522
101Abnormality of alanine metabolism (HP:0010916)2.01971639
102Hyperalaninemia (HP:0003348)2.01971639
103Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.01971639
104Nephrogenic diabetes insipidus (HP:0009806)2.01011743
105Cleft eyelid (HP:0000625)2.00304397
106Postaxial foot polydactyly (HP:0001830)1.98933105
107Furrowed tongue (HP:0000221)1.97280355
108Abnormality of placental membranes (HP:0011409)1.96451897
109Amniotic constriction ring (HP:0009775)1.96451897
110Abnormal respiratory motile cilium morphology (HP:0005938)1.96024169
111Abnormal respiratory epithelium morphology (HP:0012253)1.96024169
112Aplasia/Hypoplasia of the sacrum (HP:0008517)1.95583763
113Occipital encephalocele (HP:0002085)1.95300134
114CNS demyelination (HP:0007305)1.94326527
115Stomach cancer (HP:0012126)1.93169348
116Methylmalonic aciduria (HP:0012120)1.92599217
117Broad-based gait (HP:0002136)1.90948594
118Abnormality of the preputium (HP:0100587)1.90506898
119Emotional lability (HP:0000712)1.89795672
120Absent eyebrow (HP:0002223)1.89794638
121Pancreatic cysts (HP:0001737)1.88948126
122Abnormal spermatogenesis (HP:0008669)1.88930982
123Decreased electroretinogram (ERG) amplitude (HP:0000654)1.88599889
124Keratoconus (HP:0000563)1.85799426
125Increased corneal curvature (HP:0100692)1.85799426
126Abnormality of the corticospinal tract (HP:0002492)1.85572784
127Poor suck (HP:0002033)1.84476962
128Type I transferrin isoform profile (HP:0003642)1.84414155
129Patellar aplasia (HP:0006443)1.82517185
130Respiratory difficulties (HP:0002880)1.82429864
131Hypoplastic pelvis (HP:0008839)1.81143741
132Abnormal ciliary motility (HP:0012262)1.80649954
133Impulsivity (HP:0100710)1.79916400
134Bony spicule pigmentary retinopathy (HP:0007737)1.79249918
135Optic nerve hypoplasia (HP:0000609)1.79143229
136Genital tract atresia (HP:0001827)1.79059194
137Concave nail (HP:0001598)1.78568179
138Vaginal atresia (HP:0000148)1.78404643
139Stomatitis (HP:0010280)1.77807681
140Pachygyria (HP:0001302)1.77410475
141Trismus (HP:0000211)1.76961937
142Myokymia (HP:0002411)1.75817635
143Hypoplasia of the radius (HP:0002984)1.74456753
144Intestinal atresia (HP:0011100)1.74337554
145Postaxial hand polydactyly (HP:0001162)1.73853212
146Decreased circulating renin level (HP:0003351)1.73164820
147Absent radius (HP:0003974)1.72605747
148Constricted visual fields (HP:0001133)1.72341025
149Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72267552
150Tongue fasciculations (HP:0001308)1.72144630
151Increased intramyocellular lipid droplets (HP:0012240)1.72057636
152Meckel diverticulum (HP:0002245)1.71902635
153Limb dystonia (HP:0002451)1.70992813
154Absent rod-and cone-mediated responses on ERG (HP:0007688)1.70880423
155Hypoplasia of the capital femoral epiphysis (HP:0003090)1.69964593
156Aplasia/Hypoplasia of the patella (HP:0006498)1.69768560
157Abnormal lung lobation (HP:0002101)1.69446684
158Hemiparesis (HP:0001269)1.69176638
159Thyroiditis (HP:0100646)1.67750552
160Rough bone trabeculation (HP:0100670)1.66860867
161Hyperglycinuria (HP:0003108)1.66856700
162Abnormality of the renal collecting system (HP:0004742)1.66457730
16311 pairs of ribs (HP:0000878)1.66010737
164Tubulointerstitial nephritis (HP:0001970)1.64923150
165Hyperventilation (HP:0002883)1.64834492
166Exertional dyspnea (HP:0002875)1.64757592
167Sloping forehead (HP:0000340)1.64432808
168Abnormal urine output (HP:0012590)1.63756682
169Thyroid-stimulating hormone excess (HP:0002925)1.63041919

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.72481162
2STK163.61074994
3PLK43.02032482
4MAP4K22.98383143
5WNK32.90070681
6CASK2.78068701
7NUAK12.72433640
8TAOK32.66439722
9MAP3K122.65904940
10SRPK12.54651432
11TSSK62.37488733
12NME12.29653306
13TNIK2.24408428
14VRK12.22003300
15WEE12.18207589
16CCNB11.98085607
17CDC71.98065690
18FRK1.94633417
19PINK11.84164243
20CDK191.79592226
21EIF2AK31.77830660
22INSRR1.76621258
23EIF2AK11.73514436
24PNCK1.65319212
25VRK21.61484824
26ZAK1.61414732
27TRIM281.61291387
28PLK31.60729465
29MAP2K71.53439427
30AKT31.51088657
31OXSR11.49904979
32MAP3K21.42658524
33BCKDK1.40129413
34PLK21.38308797
35STK391.37418913
36MAPK131.35755423
37MKNK11.35204158
38MKNK21.28594192
39DAPK21.25233655
40MAP3K31.23569362
41PLK11.22819575
42TTK1.15310442
43PAK31.14187505
44PASK1.13953240
45BCR1.12614453
46CHEK21.12596991
47PIK3CA1.11553752
48ACVR1B1.10798325
49BRSK21.10107570
50YES11.09425501
51TESK21.04461167
52PBK1.04064952
53PDK41.02776766
54PDK31.02776766
55NEK61.02739025
56FGFR21.02409071
57TGFBR11.01050999
58BMPR21.01049766
59DYRK20.98472440
60MARK10.94460147
61AURKA0.91011377
62STK38L0.90971196
63TLK10.88189007
64IKBKB0.87323164
65MAP3K40.85024950
66NME20.84979837
67KIT0.82597675
68BMPR1B0.82540636
69DAPK10.78320271
70PRKCE0.78060391
71ADRBK20.77170038
72BRSK10.77003846
73MAPK150.76312808
74CAMKK20.75327929
75BRAF0.74706378
76AURKB0.74193000
77PRPF4B0.73719082
78GRK70.73384617
79PIK3CG0.71158687
80TNK20.70785540
81MUSK0.70355989
82ATR0.69947937
83CDK80.69085117
84UHMK10.67382100
85MAP2K60.66474329
86GRK10.66152650
87EIF2AK20.65800770
88CSNK2A20.65627313
89TAF10.65536248
90CSNK1G20.64926749
91MST40.64243357
92CSNK1G30.62784448
93CSNK2A10.62627566
94CAMK2B0.62397357
95CSNK1G10.62303927
96PRKCQ0.60885672
97GRK50.59477695
98RPS6KA50.57207065
99PKN10.56641463
100NEK20.55450140
101TEC0.55135961
102GRK60.54203223
103IKBKE0.54005273
104TXK0.52537054
105CSNK1A1L0.51038036
106PTK2B0.50748051
107MINK10.49806776
108CHEK10.49597103
109NTRK30.49284151
110CLK10.49221587
111PHKG10.48963516
112PHKG20.48963516
113PDK20.48816814
114MAP4K10.47046094
115ITK0.46992925
116MAPKAPK50.46889703
117CDK30.46232458
118DYRK30.46217322
119CAMK10.46006613
120STK110.45216001
121SYK0.44210383
122RPS6KB10.43863825
123NLK0.42923273
124MYLK0.42570334
125TIE10.42100214
126CDK10.41534755
127ATM0.41416866
128SIK20.41066264
129CHUK0.40737654
130PRKACA0.40437460
131PRKCI0.40403603
132STK40.40368362
133WNK40.40291793
134MAPKAPK30.40003357
135PRKCG0.38009555
136CDK20.37814784
137CDK140.36897372
138MARK30.35842794
139LYN0.35384909
140ADRBK10.35246345
141ERBB30.34779488
142NTRK20.34232044
143SGK2230.34155910
144SGK4940.34155910
145CDK180.33648566
146PIM10.33421916
147DAPK30.32977744
148EPHA40.32611577
149CAMK2A0.32611128
150FES0.31803762
151MELK0.31395512
152CSNK1D0.30766746

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.38934337
2Ribosome_Homo sapiens_hsa030104.19309955
3RNA polymerase_Homo sapiens_hsa030203.78496778
4Oxidative phosphorylation_Homo sapiens_hsa001903.71471442
5Protein export_Homo sapiens_hsa030603.11913025
6Parkinsons disease_Homo sapiens_hsa050123.02448225
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.92609631
8Mismatch repair_Homo sapiens_hsa034302.71681809
9DNA replication_Homo sapiens_hsa030302.65528815
10Spliceosome_Homo sapiens_hsa030402.55218871
11Huntingtons disease_Homo sapiens_hsa050162.48411566
12Nucleotide excision repair_Homo sapiens_hsa034202.39491904
13Basal transcription factors_Homo sapiens_hsa030222.39180667
14Homologous recombination_Homo sapiens_hsa034402.28722095
15Pyrimidine metabolism_Homo sapiens_hsa002402.22881489
16Butanoate metabolism_Homo sapiens_hsa006502.19265667
17Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.17362803
18Alzheimers disease_Homo sapiens_hsa050102.12283858
19Nitrogen metabolism_Homo sapiens_hsa009102.07634028
20RNA transport_Homo sapiens_hsa030132.01755338
21Non-homologous end-joining_Homo sapiens_hsa034501.99864746
22Fanconi anemia pathway_Homo sapiens_hsa034601.86400481
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.82896628
24Selenocompound metabolism_Homo sapiens_hsa004501.76929297
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.76881834
26Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.72931833
27RNA degradation_Homo sapiens_hsa030181.72700720
28Caffeine metabolism_Homo sapiens_hsa002321.67172101
29Collecting duct acid secretion_Homo sapiens_hsa049661.65381775
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.60808953
31Base excision repair_Homo sapiens_hsa034101.60648926
32Tryptophan metabolism_Homo sapiens_hsa003801.59891539
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.58069108
34Cell cycle_Homo sapiens_hsa041101.57064974
35Purine metabolism_Homo sapiens_hsa002301.46133641
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.45450904
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.33679732
38Propanoate metabolism_Homo sapiens_hsa006401.32799727
39Nicotine addiction_Homo sapiens_hsa050331.27700806
40SNARE interactions in vesicular transport_Homo sapiens_hsa041301.25543620
41Vitamin B6 metabolism_Homo sapiens_hsa007501.22513768
42Peroxisome_Homo sapiens_hsa041461.20459645
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.19055845
44Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.13662331
45Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09211218
46Chemical carcinogenesis_Homo sapiens_hsa052041.07183710
47Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.07062469
48One carbon pool by folate_Homo sapiens_hsa006701.06573407
49mRNA surveillance pathway_Homo sapiens_hsa030151.06311566
50Asthma_Homo sapiens_hsa053101.04757615
51Vibrio cholerae infection_Homo sapiens_hsa051101.04512755
52Cardiac muscle contraction_Homo sapiens_hsa042600.99428063
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.99176006
54Oocyte meiosis_Homo sapiens_hsa041140.96586024
55Synaptic vesicle cycle_Homo sapiens_hsa047210.92802604
56Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.86563640
57Graft-versus-host disease_Homo sapiens_hsa053320.86224640
58Fatty acid elongation_Homo sapiens_hsa000620.86087797
59Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.82684754
60ABC transporters_Homo sapiens_hsa020100.80888998
61Epstein-Barr virus infection_Homo sapiens_hsa051690.80449550
62Allograft rejection_Homo sapiens_hsa053300.79045421
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77930879
64Retinol metabolism_Homo sapiens_hsa008300.77014354
65Phototransduction_Homo sapiens_hsa047440.76818452
66Regulation of autophagy_Homo sapiens_hsa041400.72717199
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64125682
68Metabolic pathways_Homo sapiens_hsa011000.62977291
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.61233394
70Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.60405496
71beta-Alanine metabolism_Homo sapiens_hsa004100.60322304
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60129438
73Ovarian steroidogenesis_Homo sapiens_hsa049130.59139186
74Taste transduction_Homo sapiens_hsa047420.58136122
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.58048032
76Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57808907
77Insulin secretion_Homo sapiens_hsa049110.56652752
78p53 signaling pathway_Homo sapiens_hsa041150.56258228
79Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56125112
80Folate biosynthesis_Homo sapiens_hsa007900.55404387
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55108982
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54366080
83Sphingolipid metabolism_Homo sapiens_hsa006000.54276808
84Pyruvate metabolism_Homo sapiens_hsa006200.53929519
85Ether lipid metabolism_Homo sapiens_hsa005650.53874521
86Serotonergic synapse_Homo sapiens_hsa047260.52698165
87Sulfur relay system_Homo sapiens_hsa041220.50514564
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.49316716
89Amphetamine addiction_Homo sapiens_hsa050310.48704712
90Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.48240448
91Glycerolipid metabolism_Homo sapiens_hsa005610.48218250
92Rheumatoid arthritis_Homo sapiens_hsa053230.47801289
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47680132
94Sulfur metabolism_Homo sapiens_hsa009200.46769371
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.45525834
96Linoleic acid metabolism_Homo sapiens_hsa005910.44167759
97Steroid biosynthesis_Homo sapiens_hsa001000.43698230
98Calcium signaling pathway_Homo sapiens_hsa040200.43254256
99Long-term depression_Homo sapiens_hsa047300.43193218
100Arachidonic acid metabolism_Homo sapiens_hsa005900.41569081
101Pentose phosphate pathway_Homo sapiens_hsa000300.41199938
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40961767
103Salivary secretion_Homo sapiens_hsa049700.40348189
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39361549
105Alcoholism_Homo sapiens_hsa050340.39300761
106Long-term potentiation_Homo sapiens_hsa047200.38839064
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.37170158
108Morphine addiction_Homo sapiens_hsa050320.37040606
109Autoimmune thyroid disease_Homo sapiens_hsa053200.36295629
110Glutamatergic synapse_Homo sapiens_hsa047240.35210648
111NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34957354
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34654935
113Systemic lupus erythematosus_Homo sapiens_hsa053220.33909861
114Dopaminergic synapse_Homo sapiens_hsa047280.33071485
115Circadian rhythm_Homo sapiens_hsa047100.31044385
116Olfactory transduction_Homo sapiens_hsa047400.28597147
117Phagosome_Homo sapiens_hsa041450.28304299
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.25990370
119Fatty acid degradation_Homo sapiens_hsa000710.24993170
120GABAergic synapse_Homo sapiens_hsa047270.23436889
121Vitamin digestion and absorption_Homo sapiens_hsa049770.22725129
122Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.21451184
123Cocaine addiction_Homo sapiens_hsa050300.21377973
124Glutathione metabolism_Homo sapiens_hsa004800.20184569
125Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.18803562
126Tyrosine metabolism_Homo sapiens_hsa003500.18275479
127Cyanoamino acid metabolism_Homo sapiens_hsa004600.18000060
128Fructose and mannose metabolism_Homo sapiens_hsa000510.17416461
129Type I diabetes mellitus_Homo sapiens_hsa049400.16174812
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15729635
131Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.11461712
132Circadian entrainment_Homo sapiens_hsa047130.11173844
133Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.11024526
134alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.10588212
135Drug metabolism - other enzymes_Homo sapiens_hsa009830.07404522
136Arginine and proline metabolism_Homo sapiens_hsa003300.06653940
137Thyroid cancer_Homo sapiens_hsa052160.03838440
138Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.01845427
139Primary immunodeficiency_Homo sapiens_hsa053400.01332377

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