TRMT6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.70712080
2DNA replication initiation (GO:0006270)4.66077774
3DNA replication checkpoint (GO:0000076)4.62735917
4DNA strand elongation (GO:0022616)4.50346479
5DNA unwinding involved in DNA replication (GO:0006268)4.48650884
6telomere maintenance via semi-conservative replication (GO:0032201)4.33687456
7nucleobase biosynthetic process (GO:0046112)4.32385806
8ribosome assembly (GO:0042255)4.28741547
9maturation of SSU-rRNA (GO:0030490)4.25813541
10formation of translation preinitiation complex (GO:0001731)4.22344928
11CENP-A containing nucleosome assembly (GO:0034080)4.08964725
12chromatin remodeling at centromere (GO:0031055)4.07383087
13telomere maintenance via recombination (GO:0000722)4.06124237
14ribosome biogenesis (GO:0042254)4.00770034
15purine nucleobase biosynthetic process (GO:0009113)4.00355342
16establishment of integrated proviral latency (GO:0075713)3.91155344
17ribonucleoprotein complex biogenesis (GO:0022613)3.89860987
18nuclear pore organization (GO:0006999)3.89355753
19ribosomal large subunit biogenesis (GO:0042273)3.87683633
20mitotic recombination (GO:0006312)3.85992020
21pseudouridine synthesis (GO:0001522)3.85149919
22mitotic metaphase plate congression (GO:0007080)3.77168383
23ribosomal small subunit biogenesis (GO:0042274)3.75418873
24negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.72244024
25negative regulation of ligase activity (GO:0051352)3.72244024
26termination of RNA polymerase III transcription (GO:0006386)3.71846372
27transcription elongation from RNA polymerase III promoter (GO:0006385)3.71846372
28rRNA processing (GO:0006364)3.70171202
29mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.67451430
30ribosomal small subunit assembly (GO:0000028)3.65529619
31nuclear pore complex assembly (GO:0051292)3.63908290
32DNA deamination (GO:0045006)3.63160430
33telomere maintenance via telomere lengthening (GO:0010833)3.63141922
34IMP biosynthetic process (GO:0006188)3.62581307
35protein localization to kinetochore (GO:0034501)3.62053367
36establishment of protein localization to mitochondrial membrane (GO:0090151)3.59492395
37rRNA metabolic process (GO:0016072)3.57815899
38transcription from mitochondrial promoter (GO:0006390)3.57398632
39rRNA methylation (GO:0031167)3.56245849
40mitotic nuclear envelope disassembly (GO:0007077)3.47698302
41DNA replication-independent nucleosome organization (GO:0034724)3.46013283
42DNA replication-independent nucleosome assembly (GO:0006336)3.46013283
43spliceosomal snRNP assembly (GO:0000387)3.42805471
44DNA replication-dependent nucleosome assembly (GO:0006335)3.42554416
45DNA replication-dependent nucleosome organization (GO:0034723)3.42554416
46rRNA modification (GO:0000154)3.42213817
47proteasome assembly (GO:0043248)3.41369790
48mitochondrial RNA metabolic process (GO:0000959)3.40891954
49regulation of nuclear cell cycle DNA replication (GO:0033262)3.40046471
50nucleotide-excision repair, DNA gap filling (GO:0006297)3.39091862
51regulation of mitochondrial translation (GO:0070129)3.35420851
52transcription elongation from RNA polymerase I promoter (GO:0006362)3.35164345
53regulation of helicase activity (GO:0051095)3.34768047
54mitotic sister chromatid segregation (GO:0000070)3.34432215
55positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.33918688
56histone exchange (GO:0043486)3.33523386
57metaphase plate congression (GO:0051310)3.32800846
58regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.29042088
59spliceosomal complex assembly (GO:0000245)3.28750812
60regulation of cellular amino acid metabolic process (GO:0006521)3.28254752
61non-recombinational repair (GO:0000726)3.27069212
62double-strand break repair via nonhomologous end joining (GO:0006303)3.27069212
63signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25306471
64signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25306471
65signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25306471
66DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.25160648
67folic acid-containing compound biosynthetic process (GO:0009396)3.24766361
68signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.24688188
69intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.24688188
70kinetochore organization (GO:0051383)3.24096359
71signal transduction involved in DNA damage checkpoint (GO:0072422)3.22642930
72signal transduction involved in DNA integrity checkpoint (GO:0072401)3.22642930
73termination of RNA polymerase I transcription (GO:0006363)3.21632824
74translational termination (GO:0006415)3.21345175
75chaperone-mediated protein transport (GO:0072321)3.21243821
76pore complex assembly (GO:0046931)3.20753767
77positive regulation of ligase activity (GO:0051351)3.19974467
78regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.17160474
79regulation of mitotic spindle checkpoint (GO:1903504)3.17067464
80regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.17067464
81viral transcription (GO:0019083)3.16678149
82transcription-coupled nucleotide-excision repair (GO:0006283)3.16623831
83viral mRNA export from host cell nucleus (GO:0046784)3.16019795
84mitotic chromosome condensation (GO:0007076)3.15566738
85spindle checkpoint (GO:0031577)3.15540197
86signal transduction involved in cell cycle checkpoint (GO:0072395)3.14792092
87mismatch repair (GO:0006298)3.14655264
88membrane disassembly (GO:0030397)3.14295638
89nuclear envelope disassembly (GO:0051081)3.14295638
90mitotic spindle checkpoint (GO:0071174)3.12994476
91mitotic sister chromatid cohesion (GO:0007064)3.10824405
92IMP metabolic process (GO:0046040)3.10389155
93regulation of ubiquitin-protein transferase activity (GO:0051438)3.10105200
94establishment of chromosome localization (GO:0051303)3.09363462
95protein targeting to mitochondrion (GO:0006626)3.09332265
96negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.08436778
97* translational initiation (GO:0006413)3.07732775
98regulation of translational termination (GO:0006449)3.07223122
99cell cycle G1/S phase transition (GO:0044843)3.06021787
100G1/S transition of mitotic cell cycle (GO:0000082)3.06021787
101tRNA aminoacylation for protein translation (GO:0006418)3.05877671
102negative regulation of mitotic sister chromatid separation (GO:2000816)3.05169290
103negative regulation of sister chromatid segregation (GO:0033046)3.05169290
104negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.05169290
105negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.05169290
106negative regulation of mitotic sister chromatid segregation (GO:0033048)3.05169290
107SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.05112286
108DNA damage response, detection of DNA damage (GO:0042769)3.04865924
109establishment of viral latency (GO:0019043)3.03792441
1107-methylguanosine mRNA capping (GO:0006370)3.03709432
111tRNA aminoacylation (GO:0043039)3.03196621
112amino acid activation (GO:0043038)3.03196621
113negative regulation of chromosome segregation (GO:0051985)3.02870379
114cotranslational protein targeting to membrane (GO:0006613)3.02269592
115anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.02207130
116cellular component biogenesis (GO:0044085)3.02088700
117regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.01861670
118sister chromatid segregation (GO:0000819)3.01851362
119RNA capping (GO:0036260)3.01845112
1207-methylguanosine RNA capping (GO:0009452)3.01845112
121meiotic chromosome segregation (GO:0045132)3.01777712
122transcription from RNA polymerase I promoter (GO:0006360)3.01122288
123exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.00934752
124positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.00749654
125DNA geometric change (GO:0032392)3.00525687
126DNA duplex unwinding (GO:0032508)3.00017621
127RNA-dependent DNA replication (GO:0006278)2.99560957
128translation (GO:0006412)2.99507645
129DNA-templated transcription, termination (GO:0006353)2.98439844
130protein targeting to ER (GO:0045047)2.98115608
131positive regulation of chromosome segregation (GO:0051984)2.94491897
132somatic hypermutation of immunoglobulin genes (GO:0016446)2.94254031
133somatic diversification of immune receptors via somatic mutation (GO:0002566)2.94254031
134kinetochore assembly (GO:0051382)2.93525028
135RNA splicing, via transesterification reactions (GO:0000375)2.93254250
136nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.92724182
137maturation of 5.8S rRNA (GO:0000460)2.92432491
138* ncRNA processing (GO:0034470)2.92009407
139attachment of spindle microtubules to kinetochore (GO:0008608)2.91634091
140mRNA splicing, via spliceosome (GO:0000398)2.89577802
141RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.89577802
142translational elongation (GO:0006414)2.87111919
143protein localization to chromosome, centromeric region (GO:0071459)2.86902123
144* ncRNA metabolic process (GO:0034660)2.85741975
145telomere organization (GO:0032200)2.85047263

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.27033316
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.44743118
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.93798018
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.75798501
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.70881116
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.61510571
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.29046142
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.26566295
9* ETS1_20019798_ChIP-Seq_JURKAT_Human3.14574391
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.03702307
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.98814745
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.98582286
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.93169588
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.89452569
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87460997
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.80332637
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79681477
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.71997452
19VDR_23849224_ChIP-Seq_CD4+_Human2.58254661
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.54449245
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.50238232
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.35612854
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35490884
24* XRN2_22483619_ChIP-Seq_HELA_Human2.30560953
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.28839903
26ELK1_19687146_ChIP-ChIP_HELA_Human2.19878016
27FOXP3_21729870_ChIP-Seq_TREG_Human2.14231554
28THAP11_20581084_ChIP-Seq_MESCs_Mouse2.13343606
29DCP1A_22483619_ChIP-Seq_HELA_Human2.09010422
30E2F1_21310950_ChIP-Seq_MCF-7_Human2.05039251
31MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98422637
32E2F1_18555785_ChIP-Seq_MESCs_Mouse1.97952932
33* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.97341008
34GABP_19822575_ChIP-Seq_HepG2_Human1.95810485
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.94334092
36MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93573191
37TTF2_22483619_ChIP-Seq_HELA_Human1.93222639
38YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88810136
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.87371341
40AR_21909140_ChIP-Seq_LNCAP_Human1.86984820
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.86466704
42* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.82150338
43MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.80891728
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75915955
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74393157
46SRF_21415370_ChIP-Seq_HL-1_Mouse1.64400158
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.60367108
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.60140496
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.59806027
50CIITA_25753668_ChIP-Seq_RAJI_Human1.58863499
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.51046081
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49429834
53CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.49304935
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.46401178
55KDM5A_27292631_Chip-Seq_BREAST_Human1.44517638
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.44348183
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41019784
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35772743
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.35031773
60SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.29059592
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26073394
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.24811970
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23812053
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21207160
65CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.20742849
66ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.16187437
67E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15244439
68TFEB_21752829_ChIP-Seq_HELA_Human1.14759515
69MYC_18940864_ChIP-ChIP_HL60_Human1.13266037
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.10133625
71* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10003342
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06081666
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.03771762
74HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01626154
75CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99230301
76TP63_19390658_ChIP-ChIP_HaCaT_Human0.97973314
77CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95914803
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95202008
79GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94951240
80SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.94642988
81IRF1_19129219_ChIP-ChIP_H3396_Human0.94267120
82MYC_22102868_ChIP-Seq_BL_Human0.93326937
83POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92457786
84* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92151407
85KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90945938
86SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.90130248
87* SPI1_23547873_ChIP-Seq_NB4_Human0.87359218
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.85254948
89SOX2_18555785_ChIP-Seq_MESCs_Mouse0.83935630
90ELF5_23300383_ChIP-Seq_T47D_Human0.83341269
91CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83282609
92NANOG_16153702_ChIP-ChIP_HESCs_Human0.82582052
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82123222
94SALL1_21062744_ChIP-ChIP_HESCs_Human0.79968454
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.78380063
96DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.77778643
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.74576258
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.74570534
99NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.73940284
100* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73176328
101* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73133162
102KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.73099428
103KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.73099428
104KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.73099428
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.72888343
106TBX5_21415370_ChIP-Seq_HL-1_Mouse0.71904171
107PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.71433278
108DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.71174155
109TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.70791583
110TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.69128174
111CHD1_26751641_Chip-Seq_LNCaP_Human0.68353074
112EWS_26573619_Chip-Seq_HEK293_Human0.68088809
113CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.66160150

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.67797294
2MP0003693_abnormal_embryo_hatching5.76628069
3MP0010094_abnormal_chromosome_stability4.83996805
4MP0004957_abnormal_blastocyst_morpholog4.36078079
5MP0003111_abnormal_nucleus_morphology4.23799955
6MP0008058_abnormal_DNA_repair4.04662360
7MP0003077_abnormal_cell_cycle3.93644847
8MP0008877_abnormal_DNA_methylation3.01529308
9MP0008932_abnormal_embryonic_tissue2.85645470
10MP0003941_abnormal_skin_development2.50020766
11MP0003123_paternal_imprinting2.41287883
12MP0008007_abnormal_cellular_replicative2.38591664
13MP0001730_embryonic_growth_arrest2.34551609
14MP0003786_premature_aging2.30056084
15MP0000350_abnormal_cell_proliferation2.18091378
16MP0002396_abnormal_hematopoietic_system2.00362624
17MP0006036_abnormal_mitochondrial_physio1.85620437
18MP0006292_abnormal_olfactory_placode1.72941081
19MP0003890_abnormal_embryonic-extraembry1.67115233
20MP0003718_maternal_effect1.64581166
21MP0000372_irregular_coat_pigmentation1.56865134
22MP0005380_embryogenesis_phenotype1.53632157
23MP0001672_abnormal_embryogenesis/_devel1.53632157
24MP0001697_abnormal_embryo_size1.53470545
25MP0009333_abnormal_splenocyte_physiolog1.51556359
26MP0006035_abnormal_mitochondrial_morpho1.50852409
27MP0005075_abnormal_melanosome_morpholog1.50539958
28MP0003763_abnormal_thymus_physiology1.45792638
29MP0000313_abnormal_cell_death1.45689743
30MP0000490_abnormal_crypts_of1.40171011
31MP0002080_prenatal_lethality1.38523785
32MP0003121_genomic_imprinting1.37990705
33MP0010234_abnormal_vibrissa_follicle1.36139669
34MP0000015_abnormal_ear_pigmentation1.34682664
35MP0003984_embryonic_growth_retardation1.33925205
36MP0010307_abnormal_tumor_latency1.28340240
37MP0002085_abnormal_embryonic_tissue1.27531877
38MP0002088_abnormal_embryonic_growth/wei1.27373139
39MP0010352_gastrointestinal_tract_polyps1.26733009
40MP0002210_abnormal_sex_determination1.23778000
41MP0002102_abnormal_ear_morphology1.22649304
42MP0002019_abnormal_tumor_incidence1.22142656
43MP0002796_impaired_skin_barrier1.21880528
44MP0001853_heart_inflammation1.18990439
45MP0002084_abnormal_developmental_patter1.17088511
46MP0002160_abnormal_reproductive_system1.15570682
47MP0000703_abnormal_thymus_morphology1.12624480
48MP0005501_abnormal_skin_physiology1.09534638
49MP0002398_abnormal_bone_marrow1.08647755
50MP0004808_abnormal_hematopoietic_stem1.08361998
51MP0001145_abnormal_male_reproductive1.07790349
52MP0002132_abnormal_respiratory_system1.04698629
53MP0002086_abnormal_extraembryonic_tissu1.03807937
54MP0005174_abnormal_tail_pigmentation1.03692991
55MP0005451_abnormal_body_composition1.02418203
56MP0005171_absent_coat_pigmentation1.01887219
57MP0009697_abnormal_copulation0.99738394
58MP0004197_abnormal_fetal_growth/weight/0.98572906
59MP0001929_abnormal_gametogenesis0.98148354
60MP0003315_abnormal_perineum_morphology0.98051248
61MP0003806_abnormal_nucleotide_metabolis0.92950140
62MP0005389_reproductive_system_phenotype0.92819340
63MP0002751_abnormal_autonomic_nervous0.91241656
64MP0002006_tumorigenesis0.91164668
65MP0002722_abnormal_immune_system0.90994843
66MP0002095_abnormal_skin_pigmentation0.90933288
67MP0003567_abnormal_fetal_cardiomyocyte0.90793291
68MP0001529_abnormal_vocalization0.88734534
69MP0001216_abnormal_epidermal_layer0.87876213
70MP0000653_abnormal_sex_gland0.87435210
71MP0002938_white_spotting0.86380184
72MP0000689_abnormal_spleen_morphology0.84546147
73MP0005408_hypopigmentation0.84128687
74MP0001293_anophthalmia0.83379233
75MP0000762_abnormal_tongue_morphology0.81882236
76MP0002429_abnormal_blood_cell0.79332264
77MP0002163_abnormal_gland_morphology0.78965674
78MP0008789_abnormal_olfactory_epithelium0.78149928
79MP0001881_abnormal_mammary_gland0.77998697
80MP0000579_abnormal_nail_morphology0.77933825
81MP0000627_abnormal_mammary_gland0.77371098
82MP0003950_abnormal_plasma_membrane0.76188496
83MP0006072_abnormal_retinal_apoptosis0.75972458
84MP0004133_heterotaxia0.75442722
85MP0003136_yellow_coat_color0.74577579
86MP0005384_cellular_phenotype0.73567899
87MP0003937_abnormal_limbs/digits/tail_de0.73419472
88MP0002060_abnormal_skin_morphology0.72445139
89MP0005671_abnormal_response_to0.72141563
90MP0002638_abnormal_pupillary_reflex0.72009148
91MP0005084_abnormal_gallbladder_morpholo0.70478248
92MP0000716_abnormal_immune_system0.70326832
93MP0003119_abnormal_digestive_system0.69049854
94MP0005395_other_phenotype0.68072217
95MP0000358_abnormal_cell_content/0.67625867
96MP0008995_early_reproductive_senescence0.67345481
97MP0005266_abnormal_metabolism0.67244954
98MP0008260_abnormal_autophagy0.66990997
99MP0001286_abnormal_eye_development0.66937722
100MP0001119_abnormal_female_reproductive0.65824478
101MP0001485_abnormal_pinna_reflex0.65322247
102MP0005621_abnormal_cell_physiology0.64357300
103MP0001188_hyperpigmentation0.63501952
104MP0002420_abnormal_adaptive_immunity0.60375153
105MP0010678_abnormal_skin_adnexa0.60172649
106MP0003195_calcinosis0.59579196
107MP0002697_abnormal_eye_size0.58704407
108MP0003186_abnormal_redox_activity0.58183333
109MP0002148_abnormal_hypersensitivity_rea0.57959571
110MP0001819_abnormal_immune_cell0.57873958
111MP0010030_abnormal_orbit_morphology0.57739721
112MP0002009_preneoplasia0.57198772
113MP0009703_decreased_birth_body0.56948641
114MP0001186_pigmentation_phenotype0.56513033
115MP0005397_hematopoietic_system_phenotyp0.56203388
116MP0001545_abnormal_hematopoietic_system0.56203388
117MP0002269_muscular_atrophy0.55330900
118MP0002075_abnormal_coat/hair_pigmentati0.54340999
119MP0003938_abnormal_ear_development0.53823983
120MP0009672_abnormal_birth_weight0.53587563
121MP0008873_increased_physiological_sensi0.53366867
122MP0001919_abnormal_reproductive_system0.53034013
123MP0003699_abnormal_female_reproductive0.52899608
124MP0001905_abnormal_dopamine_level0.52802430
125MP0003936_abnormal_reproductive_system0.52205410
126MP0002111_abnormal_tail_morphology0.51949605
127MP0006054_spinal_hemorrhage0.51847844
128MP0002405_respiratory_system_inflammati0.51834434
129MP0003221_abnormal_cardiomyocyte_apopto0.51559852
130MP0001727_abnormal_embryo_implantation0.51420265
131MP0005410_abnormal_fertilization0.51395364
132MP0002723_abnormal_immune_serum0.51257693
133MP0002877_abnormal_melanocyte_morpholog0.51241906

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.49375843
2Chromsome breakage (HP:0040012)4.81226997
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.63332699
4Acute necrotizing encephalopathy (HP:0006965)4.28795118
5Abnormal mitochondria in muscle tissue (HP:0008316)3.94226317
6Reticulocytopenia (HP:0001896)3.75984922
7Breast hypoplasia (HP:0003187)3.70296863
8Acute encephalopathy (HP:0006846)3.67996614
9Abnormality of cells of the erythroid lineage (HP:0012130)3.65965065
10Cerebral hypomyelination (HP:0006808)3.53534906
11Progressive macrocephaly (HP:0004481)3.51727651
12Abnormal number of erythroid precursors (HP:0012131)3.48522616
13Increased CSF lactate (HP:0002490)3.45848360
14Agnosia (HP:0010524)3.45447544
15Mitochondrial inheritance (HP:0001427)3.38752789
16Abnormality of chromosome stability (HP:0003220)3.37400485
17Abnormality of the preputium (HP:0100587)3.32000031
18Premature graying of hair (HP:0002216)3.26317495
19Oral leukoplakia (HP:0002745)3.10361942
20Meckel diverticulum (HP:0002245)3.09977084
21Duplicated collecting system (HP:0000081)3.04715178
22Rough bone trabeculation (HP:0100670)3.01453796
23Aplasia/Hypoplasia of the uvula (HP:0010293)2.98874292
24Aplastic anemia (HP:0001915)2.97111105
25Abnormality of methionine metabolism (HP:0010901)2.92720776
26Cerebral edema (HP:0002181)2.92598524
27Abnormality of the ileum (HP:0001549)2.90740392
28Abnormality of the renal collecting system (HP:0004742)2.89738367
29Renal Fanconi syndrome (HP:0001994)2.88965236
30Type I transferrin isoform profile (HP:0003642)2.86048678
31Multiple enchondromatosis (HP:0005701)2.84580178
32Microvesicular hepatic steatosis (HP:0001414)2.81233157
33Increased intramyocellular lipid droplets (HP:0012240)2.80832644
34Increased serum pyruvate (HP:0003542)2.78317531
35Bone marrow hypocellularity (HP:0005528)2.75935677
36Selective tooth agenesis (HP:0001592)2.74582223
37Amniotic constriction ring (HP:0009775)2.69674546
38Abnormality of placental membranes (HP:0011409)2.69674546
39Absent radius (HP:0003974)2.69636983
40Absent thumb (HP:0009777)2.68155275
41Patellar aplasia (HP:0006443)2.66365356
42Abnormality of the anterior horn cell (HP:0006802)2.66142220
43Degeneration of anterior horn cells (HP:0002398)2.66142220
44Macrocytic anemia (HP:0001972)2.65408729
45Colon cancer (HP:0003003)2.64765355
46Abnormality of glycolysis (HP:0004366)2.59025035
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.58121840
48Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.58121840
49Aplasia involving forearm bones (HP:0009822)2.58026785
50Absent forearm bone (HP:0003953)2.58026785
51Hepatocellular necrosis (HP:0001404)2.57326460
52Sparse eyelashes (HP:0000653)2.57269832
53Medulloblastoma (HP:0002885)2.57072108
54Respiratory difficulties (HP:0002880)2.56971614
55Myelodysplasia (HP:0002863)2.54523326
56Small intestinal stenosis (HP:0012848)2.51281618
57Duodenal stenosis (HP:0100867)2.51281618
58Exercise intolerance (HP:0003546)2.47718199
59Carpal bone hypoplasia (HP:0001498)2.47571498
60Aplasia/Hypoplasia of the patella (HP:0006498)2.46424111
61Lactic acidosis (HP:0003128)2.45164856
62Asplenia (HP:0001746)2.44441996
63Hepatic necrosis (HP:0002605)2.42948763
64Increased hepatocellular lipid droplets (HP:0006565)2.42723628
65Reduced antithrombin III activity (HP:0001976)2.41712912
66Stenosis of the external auditory canal (HP:0000402)2.41294763
67Cleft eyelid (HP:0000625)2.41001874
68Horseshoe kidney (HP:0000085)2.39695328
69Abnormal lung lobation (HP:0002101)2.38129208
70Pallor (HP:0000980)2.35358332
71Progressive muscle weakness (HP:0003323)2.34863747
72Sloping forehead (HP:0000340)2.34855493
73Aplasia/Hypoplasia of the spleen (HP:0010451)2.32906217
74Rhabdomyosarcoma (HP:0002859)2.31598804
75Ectopic kidney (HP:0000086)2.30319480
76Leukodystrophy (HP:0002415)2.26970702
77Aplasia/hypoplasia of the uterus (HP:0008684)2.25517467
78Methylmalonic acidemia (HP:0002912)2.25328759
79Impulsivity (HP:0100710)2.22545968
8011 pairs of ribs (HP:0000878)2.21245475
81Abnormality of the labia minora (HP:0012880)2.21079224
82Aplasia/Hypoplasia of the sacrum (HP:0008517)2.20673570
83Cutaneous melanoma (HP:0012056)2.20135239
84Lymphoma (HP:0002665)2.19932039
85Abnormal trabecular bone morphology (HP:0100671)2.19605008
86Ependymoma (HP:0002888)2.18926567
87CNS hypomyelination (HP:0003429)2.17750743
88Nephroblastoma (Wilms tumor) (HP:0002667)2.17572019
89Cellular immunodeficiency (HP:0005374)2.17148849
90Hypoplasia of the uterus (HP:0000013)2.15549591
91Tracheoesophageal fistula (HP:0002575)2.14781425
92Abnormality of aspartate family amino acid metabolism (HP:0010899)2.14033208
93Embryonal renal neoplasm (HP:0011794)2.11720635
94Glossoptosis (HP:0000162)2.11266876
95Increased muscle lipid content (HP:0009058)2.10035771
963-Methylglutaconic aciduria (HP:0003535)2.09937367
97Abnormality of the duodenum (HP:0002246)2.09822611
98IgM deficiency (HP:0002850)2.09427453
99Abnormality of alanine metabolism (HP:0010916)2.09276379
100Hyperalaninemia (HP:0003348)2.09276379
101Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.09276379
102Exertional dyspnea (HP:0002875)2.08346685
103Progressive external ophthalmoplegia (HP:0000590)2.07672041
104Neoplasm of the pancreas (HP:0002894)2.07044329
105Abnormal number of incisors (HP:0011064)2.06665803
106Secondary amenorrhea (HP:0000869)2.04886047
107Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02981515
108Pancreatic cysts (HP:0001737)2.01955257
109Atresia of the external auditory canal (HP:0000413)2.01915118
110Increased serum lactate (HP:0002151)2.01545932
111Pancytopenia (HP:0001876)2.01178981
112Upper limb muscle weakness (HP:0003484)2.00684820
113Premature ovarian failure (HP:0008209)2.00534143
114Respiratory failure (HP:0002878)1.99945556
115Triphalangeal thumb (HP:0001199)1.99676003
116Megaloblastic anemia (HP:0001889)1.98089627
117Ureteral duplication (HP:0000073)1.97569389
118Trismus (HP:0000211)1.97523302
119Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.96458485
120Facial cleft (HP:0002006)1.96302580
121Abnormalities of placenta or umbilical cord (HP:0001194)1.96040193
122Abnormality of serum amino acid levels (HP:0003112)1.95987074
123Pulmonary fibrosis (HP:0002206)1.95236495
124Basal cell carcinoma (HP:0002671)1.94135971
125Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.92956553
126Abnormal protein N-linked glycosylation (HP:0012347)1.92956553
127Abnormal protein glycosylation (HP:0012346)1.92956553
128Abnormal glycosylation (HP:0012345)1.92956553
129Lipid accumulation in hepatocytes (HP:0006561)1.91422150
130Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.91306052
131Supernumerary spleens (HP:0009799)1.91205969
132Microretrognathia (HP:0000308)1.90213043
133Postnatal microcephaly (HP:0005484)1.90098179
134Gonadotropin excess (HP:0000837)1.88260980
135Short thumb (HP:0009778)1.88091506
136Volvulus (HP:0002580)1.87890788
137Abnormality of the carotid arteries (HP:0005344)1.87401628
138Squamous cell carcinoma (HP:0002860)1.87294873
139Tongue fasciculations (HP:0001308)1.86733022
140Neoplasm of the adrenal gland (HP:0100631)1.86687004
141Thrombocytosis (HP:0001894)1.86505667
142Abnormal spermatogenesis (HP:0008669)1.86224403
143Hypoplasia of the capital femoral epiphysis (HP:0003090)1.84779024
144Amaurosis fugax (HP:0100576)1.82315141
145Clubbing of toes (HP:0100760)1.81995254
146Proximal placement of thumb (HP:0009623)1.81575821
147Sensory axonal neuropathy (HP:0003390)1.80753976

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.28165043
2CDC74.27437963
3BUB13.98209578
4SRPK13.14142185
5TSSK62.92578150
6VRK22.83209437
7BRSK22.72084573
8STK162.56631951
9EIF2AK12.55492107
10PRPF4B2.27544105
11EIF2AK32.26735091
12VRK12.22612797
13NME22.18968337
14TTK2.06660701
15ACVR1B1.99050849
16NUAK11.88695155
17PLK11.87324679
18NEK21.86124448
19PASK1.84201974
20TRIM281.81683791
21TLK11.79214867
22MKNK11.76832036
23PLK31.75077888
24BRSK11.61829649
25PLK41.59422444
26CDK121.59032649
27MKNK21.58439623
28ATR1.57238562
29CDK71.50757892
30TAF11.39063839
31CHEK21.34465637
32CLK11.33737497
33MST41.33688982
34AURKB1.29412744
35STK38L1.27868681
36DYRK31.27166071
37TESK21.26987529
38CCNB11.26552449
39PNCK1.21724938
40MAP3K121.20770954
41CHEK11.19533710
42STK241.17978403
43AURKA1.17959245
44ARAF1.17146108
45MAP3K91.14648488
46PBK1.14271204
47CDK81.12767531
48NME11.11924673
49CDK41.11654282
50PDK21.05139861
51BCR1.04180198
52RPS6KB21.03555282
53MST1R1.02833187
54MELK1.00880986
55CDK190.99679720
56ERBB30.98574169
57EPHA20.97911812
58BRD40.97862020
59ZAK0.96783522
60STK40.93309691
61PIM20.93127322
62IRAK40.92195833
63CSNK2A20.89098364
64NEK60.87976759
65NEK10.87806117
66ATM0.87687076
67ERBB40.86802873
68MAP3K80.83386895
69PRKCI0.82013489
70TAOK20.81819700
71CDK20.81758386
72SCYL20.80468178
73RPS6KA40.79437658
74TNIK0.79429622
75IRAK30.74556769
76CSNK2A10.72581135
77PIM10.69330553
78BRAF0.66836907
79CDK10.65822378
80RPS6KA50.65249515
81STK100.64371814
82EIF2AK20.62356843
83UHMK10.59691402
84CDK90.59211116
85DMPK0.57967303
86ALK0.56764264
87CSNK1E0.55080818
88MAP4K10.54542066
89PAK10.54066816
90RAF10.49866100
91PAK40.46806649
92AKT30.46697748
93TEC0.46420791
94CSNK1G10.45669311
95SIK30.44340459
96TESK10.42458847
97LATS10.42143222
98DAPK10.41974280
99ABL20.41628479
100AKT20.41571551
101PRKDC0.41204312
102LMTK20.39380631
103CSNK1G30.39158678
104MOS0.38962237
105BMPR20.38257536
106CDK180.37867201
107ILK0.36253516
108FLT30.35048011
109PLK20.34572394
110CAMKK20.34482048
111BMPR1B0.34198789
112DYRK20.33834699
113TGFBR10.33823535
114MAP3K140.33725692
115YES10.32474531
116MAP3K130.32305100
117CDK11A0.31578424
118CDK150.31571251
119TXK0.30581982
120CDK60.30219510
121BTK0.30172746
122CDK140.30017579
123LIMK10.29927815
124MET0.28746950
125MAPK140.28724523
126GRK60.26498619
127CASK0.26425953
128CSNK1G20.26361972
129STK30.26074531

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.60879303
2Mismatch repair_Homo sapiens_hsa034304.39216160
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.09356147
4RNA polymerase_Homo sapiens_hsa030203.82169982
5Proteasome_Homo sapiens_hsa030503.58254412
6Ribosome_Homo sapiens_hsa030103.42174650
7Spliceosome_Homo sapiens_hsa030403.32820857
8Homologous recombination_Homo sapiens_hsa034403.11580211
9RNA transport_Homo sapiens_hsa030133.06258455
10Base excision repair_Homo sapiens_hsa034102.65895491
11Nucleotide excision repair_Homo sapiens_hsa034202.64681747
12Pyrimidine metabolism_Homo sapiens_hsa002402.55494902
13Cell cycle_Homo sapiens_hsa041102.49185962
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.41775533
15One carbon pool by folate_Homo sapiens_hsa006702.34136362
16Fanconi anemia pathway_Homo sapiens_hsa034602.31603430
17Non-homologous end-joining_Homo sapiens_hsa034502.30802359
18Protein export_Homo sapiens_hsa030602.12541242
19Basal transcription factors_Homo sapiens_hsa030222.12319727
20RNA degradation_Homo sapiens_hsa030182.00731495
21mRNA surveillance pathway_Homo sapiens_hsa030151.84267691
22Purine metabolism_Homo sapiens_hsa002301.50861151
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.43992302
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42300148
25p53 signaling pathway_Homo sapiens_hsa041151.22966939
26Epstein-Barr virus infection_Homo sapiens_hsa051691.22846057
27Pyruvate metabolism_Homo sapiens_hsa006201.01600432
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93803411
29Oocyte meiosis_Homo sapiens_hsa041140.91002636
30Oxidative phosphorylation_Homo sapiens_hsa001900.90994632
31Parkinsons disease_Homo sapiens_hsa050120.87362066
32Sulfur metabolism_Homo sapiens_hsa009200.86425182
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.85941611
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.85153781
35Antigen processing and presentation_Homo sapiens_hsa046120.84059271
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83661500
37Huntingtons disease_Homo sapiens_hsa050160.82768452
38Herpes simplex infection_Homo sapiens_hsa051680.79676452
39Fatty acid elongation_Homo sapiens_hsa000620.78394444
40Propanoate metabolism_Homo sapiens_hsa006400.77460239
41Systemic lupus erythematosus_Homo sapiens_hsa053220.77337709
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75023198
43Steroid biosynthesis_Homo sapiens_hsa001000.74701983
44Viral carcinogenesis_Homo sapiens_hsa052030.73972869
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72265574
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69291584
47Carbon metabolism_Homo sapiens_hsa012000.68474761
48Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63294831
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.60541713
50Type I diabetes mellitus_Homo sapiens_hsa049400.60209232
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59594964
52Primary immunodeficiency_Homo sapiens_hsa053400.59102504
53Vitamin B6 metabolism_Homo sapiens_hsa007500.56562179
54N-Glycan biosynthesis_Homo sapiens_hsa005100.55445839
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.54895553
56Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.52853151
57HTLV-I infection_Homo sapiens_hsa051660.52833267
58Sulfur relay system_Homo sapiens_hsa041220.52560847
59Allograft rejection_Homo sapiens_hsa053300.49922708
60Folate biosynthesis_Homo sapiens_hsa007900.48692519
61Regulation of autophagy_Homo sapiens_hsa041400.46436565
62Drug metabolism - other enzymes_Homo sapiens_hsa009830.43628236
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43561924
64Pentose phosphate pathway_Homo sapiens_hsa000300.43380011
65Legionellosis_Homo sapiens_hsa051340.43118101
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.41752934
67Graft-versus-host disease_Homo sapiens_hsa053320.40223022
68Alzheimers disease_Homo sapiens_hsa050100.39899555
69Thyroid cancer_Homo sapiens_hsa052160.39189873
70Alcoholism_Homo sapiens_hsa050340.38574829
71Autoimmune thyroid disease_Homo sapiens_hsa053200.38411804
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37036516
73Measles_Homo sapiens_hsa051620.35785980
74Asthma_Homo sapiens_hsa053100.33199986
75Cardiac muscle contraction_Homo sapiens_hsa042600.31402805
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31401061
77Selenocompound metabolism_Homo sapiens_hsa004500.30653875
78Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29944901
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.29909997
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.29745673
81MicroRNAs in cancer_Homo sapiens_hsa052060.28226596
82Shigellosis_Homo sapiens_hsa051310.27804613
83Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27297689
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.25441373
85Hepatitis B_Homo sapiens_hsa051610.24071333
86Glutathione metabolism_Homo sapiens_hsa004800.23700413
87Metabolic pathways_Homo sapiens_hsa011000.23600313
88Collecting duct acid secretion_Homo sapiens_hsa049660.23051716
89Maturity onset diabetes of the young_Homo sapiens_hsa049500.22514123
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.21575716
91Biosynthesis of amino acids_Homo sapiens_hsa012300.21042092
92Colorectal cancer_Homo sapiens_hsa052100.20926508
93Arachidonic acid metabolism_Homo sapiens_hsa005900.20180181
94Vibrio cholerae infection_Homo sapiens_hsa051100.20146180
95Peroxisome_Homo sapiens_hsa041460.19849003
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16624583
97TGF-beta signaling pathway_Homo sapiens_hsa043500.16562411
98Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.16433077
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.15679597
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.15633646
101Hematopoietic cell lineage_Homo sapiens_hsa046400.15240620
102Apoptosis_Homo sapiens_hsa042100.13446592
103Sphingolipid metabolism_Homo sapiens_hsa006000.12763570
104RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.12478649
105Hippo signaling pathway_Homo sapiens_hsa043900.12177212
106Phagosome_Homo sapiens_hsa041450.11279707
107Small cell lung cancer_Homo sapiens_hsa052220.11236842
108Wnt signaling pathway_Homo sapiens_hsa043100.11054709
109Bladder cancer_Homo sapiens_hsa052190.10978886
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.10758808
111Influenza A_Homo sapiens_hsa051640.09612502
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.08623198
113T cell receptor signaling pathway_Homo sapiens_hsa046600.07986434
114Basal cell carcinoma_Homo sapiens_hsa052170.07792806
115Pathways in cancer_Homo sapiens_hsa052000.07709595
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.07008723
117Arginine biosynthesis_Homo sapiens_hsa002200.06738565
118Other glycan degradation_Homo sapiens_hsa005110.06374869
119Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.06336018
120Linoleic acid metabolism_Homo sapiens_hsa005910.04846240
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.04641690
122Galactose metabolism_Homo sapiens_hsa000520.03143244
123Fructose and mannose metabolism_Homo sapiens_hsa000510.02995696
124Circadian rhythm_Homo sapiens_hsa047100.01592517
125Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.01061144
126Arginine and proline metabolism_Homo sapiens_hsa00330-0.0094307
127Lysine degradation_Homo sapiens_hsa00310-0.0058233
128Phototransduction_Homo sapiens_hsa04744-0.0029077

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »