TSGA10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)9.23321753
2axonemal dynein complex assembly (GO:0070286)8.73432214
3epithelial cilium movement (GO:0003351)8.59625758
4sperm motility (GO:0030317)8.36061832
5acrosome assembly (GO:0001675)8.10124740
6cilium movement (GO:0003341)8.01407362
7multicellular organism reproduction (GO:0032504)7.83234215
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.80380344
9motile cilium assembly (GO:0044458)7.75281931
10acrosome reaction (GO:0007340)7.34072777
11cell wall macromolecule catabolic process (GO:0016998)7.32507315
12cell wall macromolecule metabolic process (GO:0044036)7.32507315
13plasma membrane fusion (GO:0045026)7.24702811
14piRNA metabolic process (GO:0034587)7.09338521
15sperm-egg recognition (GO:0035036)7.08456743
16regulation of cilium movement (GO:0003352)6.63962223
17male meiosis (GO:0007140)6.40207676
18spermatid development (GO:0007286)6.36359044
19cell-cell recognition (GO:0009988)6.28158466
20reproduction (GO:0000003)6.20016085
21binding of sperm to zona pellucida (GO:0007339)6.19336111
22synaptonemal complex organization (GO:0070193)5.38250603
23single fertilization (GO:0007338)5.33918432
24protein localization to cilium (GO:0061512)5.25271246
25ventricular system development (GO:0021591)5.23252772
26DNA methylation involved in gamete generation (GO:0043046)5.08000667
27synaptonemal complex assembly (GO:0007130)4.93046407
28sperm capacitation (GO:0048240)4.75630129
29negative regulation of inclusion body assembly (GO:0090084)4.61784637
30intraciliary transport (GO:0042073)4.60738591
31calcium ion-dependent exocytosis (GO:0017156)4.55804360
32fertilization (GO:0009566)4.49461725
33male meiosis I (GO:0007141)4.43654091
34axoneme assembly (GO:0035082)4.29068047
35microtubule depolymerization (GO:0007019)4.25391841
36cellular ketone body metabolic process (GO:0046950)4.16810754
37* spermatogenesis (GO:0007283)4.13742724
38* male gamete generation (GO:0048232)4.12535810
39microtubule severing (GO:0051013)3.98347787
40protein polyglutamylation (GO:0018095)3.87892637
41cilium organization (GO:0044782)3.87050539
42regulation of microtubule-based movement (GO:0060632)3.86094536
43* gamete generation (GO:0007276)3.83859391
44cell recognition (GO:0008037)3.81596680
45cilium assembly (GO:0042384)3.81117905
46one-carbon compound transport (GO:0019755)3.80423761
47ketone body metabolic process (GO:1902224)3.74848075
48regulation of inclusion body assembly (GO:0090083)3.70159159
49photoreceptor cell maintenance (GO:0045494)3.69207759
50germ cell development (GO:0007281)3.65528815
51cellular process involved in reproduction in multicellular organism (GO:0022412)3.65166984
52rRNA catabolic process (GO:0016075)3.60661009
53chromosome organization involved in meiosis (GO:0070192)3.53322882
54polyol catabolic process (GO:0046174)3.51241388
55protein targeting to Golgi (GO:0000042)3.47736635
56meiotic nuclear division (GO:0007126)3.47200562
57spermatid nucleus differentiation (GO:0007289)3.42658096
58cellular component assembly involved in morphogenesis (GO:0010927)3.36168624
59* cell projection assembly (GO:0030031)3.34914072
60microtubule-based movement (GO:0007018)3.33854662
61cilium morphogenesis (GO:0060271)3.33743700
62meiosis I (GO:0007127)3.33423074
63retinal cone cell development (GO:0046549)3.30489337
64retrograde transport, vesicle recycling within Golgi (GO:0000301)3.30236235
65centriole assembly (GO:0098534)3.29094701
66left/right pattern formation (GO:0060972)3.20754127
67ionotropic glutamate receptor signaling pathway (GO:0035235)3.20169362
68seminiferous tubule development (GO:0072520)3.12580671
69organic cation transport (GO:0015695)3.11869762
70neuron cell-cell adhesion (GO:0007158)3.08770311
71rRNA methylation (GO:0031167)3.05431192
72protein localization to Golgi apparatus (GO:0034067)3.02354257
73synapsis (GO:0007129)2.99573941
74meiotic cell cycle (GO:0051321)2.99361766
75presynaptic membrane assembly (GO:0097105)2.98960733
76membrane depolarization during action potential (GO:0086010)2.98512744
77* multicellular organismal reproductive process (GO:0048609)2.97910508
78lactate metabolic process (GO:0006089)2.96809462
79determination of left/right symmetry (GO:0007368)2.94534914
80protein localization to synapse (GO:0035418)2.93837775
81calcium ion import (GO:0070509)2.90877480
82protein K11-linked deubiquitination (GO:0035871)2.89850149
83primary alcohol catabolic process (GO:0034310)2.89180888
84genitalia morphogenesis (GO:0035112)2.88105252
85vitamin transmembrane transport (GO:0035461)2.87814694
86centriole replication (GO:0007099)2.86091161
87smoothened signaling pathway (GO:0007224)2.83862497
88monoubiquitinated protein deubiquitination (GO:0035520)2.82348833
89rRNA modification (GO:0000154)2.81694392
90retinal rod cell development (GO:0046548)2.79417248
91determination of bilateral symmetry (GO:0009855)2.77899275
92single strand break repair (GO:0000012)2.77390228
93neural tube formation (GO:0001841)2.76730154
94regulation of hexokinase activity (GO:1903299)2.76665904
95regulation of glucokinase activity (GO:0033131)2.76665904
96glutathione derivative metabolic process (GO:1901685)2.75554350
97glutathione derivative biosynthetic process (GO:1901687)2.75554350
98mitochondrion degradation (GO:0000422)2.74585455
99nucleoside diphosphate phosphorylation (GO:0006165)2.73467328
100regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.72249179
101presynaptic membrane organization (GO:0097090)2.71986789
102phosphatidylethanolamine biosynthetic process (GO:0006646)2.70493383
103base-excision repair, AP site formation (GO:0006285)2.70377441
104specification of symmetry (GO:0009799)2.70170355
105glutamate receptor signaling pathway (GO:0007215)2.69650525
106positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.68957338
107regulation of protein glycosylation (GO:0060049)2.67276320
108phosphatidylethanolamine metabolic process (GO:0046337)2.66488620
109negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.65075370
110regulation of meiosis I (GO:0060631)2.65066895
111mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.64667231
112establishment of protein localization to Golgi (GO:0072600)2.64069025
113diterpenoid biosynthetic process (GO:0016102)2.62376800
114nonmotile primary cilium assembly (GO:0035058)2.61655772
115pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.60532052
116lateral ventricle development (GO:0021670)2.60455888
117startle response (GO:0001964)2.58904849
118synaptic transmission, glutamatergic (GO:0035249)2.58591938
119GTP biosynthetic process (GO:0006183)2.57195672
120microtubule polymerization or depolymerization (GO:0031109)2.56600308
121retinoic acid metabolic process (GO:0042573)2.56191182
122vocalization behavior (GO:0071625)2.55785374
123reciprocal DNA recombination (GO:0035825)2.50557056
124reciprocal meiotic recombination (GO:0007131)2.50557056
125regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.50351817
126response to nitrosative stress (GO:0051409)2.49175879
127regulation of protein polyubiquitination (GO:1902914)2.47101961
128detection of light stimulus involved in sensory perception (GO:0050962)2.46947565
129detection of light stimulus involved in visual perception (GO:0050908)2.46947565
130spinal cord motor neuron differentiation (GO:0021522)2.46021141
131cytoplasmic microtubule organization (GO:0031122)2.45652617
132leukotriene biosynthetic process (GO:0019370)2.44990224
133membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.44134496
134ethanol metabolic process (GO:0006067)2.43429692
135inositol phosphate catabolic process (GO:0071545)2.43111074
136neuron-neuron synaptic transmission (GO:0007270)2.42823192
137organelle assembly (GO:0070925)2.42150304
138intra-S DNA damage checkpoint (GO:0031573)2.41062338
139cellular extravasation (GO:0045123)2.40215447
140inositol phosphate dephosphorylation (GO:0046855)2.40082403
141phosphorylated carbohydrate dephosphorylation (GO:0046838)2.40082403
142regulation of glutamate receptor signaling pathway (GO:1900449)2.40015588
143left/right axis specification (GO:0070986)2.37328602
144microtubule bundle formation (GO:0001578)2.37135146
145negative regulation of organelle assembly (GO:1902116)2.35153551
146multicellular organismal development (GO:0007275)2.33503338
147cilium or flagellum-dependent cell motility (GO:0001539)11.6637945

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.61705688
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.16295702
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.65885343
4GBX2_23144817_ChIP-Seq_PC3_Human3.02974386
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.02270105
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.56872396
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.50549054
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.33855453
9TAF15_26573619_Chip-Seq_HEK293_Human2.27168614
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.22529540
11* FLI1_27457419_Chip-Seq_LIVER_Mouse2.14153491
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12159637
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.07281301
14EWS_26573619_Chip-Seq_HEK293_Human2.04261504
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.03146743
16VDR_22108803_ChIP-Seq_LS180_Human1.91302522
17REST_21632747_ChIP-Seq_MESCs_Mouse1.89829787
18* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88934406
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.86907471
20* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.86674790
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.79396612
22SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74643247
23ZNF274_21170338_ChIP-Seq_K562_Hela1.71293809
24SMAD4_21799915_ChIP-Seq_A2780_Human1.70748451
25* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.68312382
26RNF2_27304074_Chip-Seq_NSC_Mouse1.62349760
27* NANOG_18555785_Chip-Seq_ESCs_Mouse1.59967675
28FUS_26573619_Chip-Seq_HEK293_Human1.59791089
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.58896091
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.58719754
31P300_19829295_ChIP-Seq_ESCs_Human1.56701446
32TCF4_22108803_ChIP-Seq_LS180_Human1.52157977
33ER_23166858_ChIP-Seq_MCF-7_Human1.51349930
34POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.49598951
35TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49598951
36* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.49015596
37FOXA1_27270436_Chip-Seq_PROSTATE_Human1.46705700
38FOXA1_25329375_ChIP-Seq_VCAP_Human1.46705700
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.46393543
40NR3C1_21868756_ChIP-Seq_MCF10A_Human1.46180536
41KDM2B_26808549_Chip-Seq_REH_Human1.46029172
42* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45870764
43MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.45644574
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44562822
45AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43824623
46TAL1_26923725_Chip-Seq_HPCs_Mouse1.41580376
47SMAD4_21741376_ChIP-Seq_EPCs_Human1.41337792
48EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.40877386
49* P53_22387025_ChIP-Seq_ESCs_Mouse1.40262143
50TCF4_23295773_ChIP-Seq_U87_Human1.40013254
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39445164
52SOX2_19829295_ChIP-Seq_ESCs_Human1.39048555
53NANOG_19829295_ChIP-Seq_ESCs_Human1.39048555
54TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.38028532
55* TP53_22573176_ChIP-Seq_HFKS_Human1.37426184
56* NFE2_27457419_Chip-Seq_LIVER_Mouse1.37348251
57FOXA1_21572438_ChIP-Seq_LNCaP_Human1.36530230
58* RUNX2_22187159_ChIP-Seq_PCA_Human1.36273094
59KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.36234555
60CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36005713
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.35906290
62FOXM1_26456572_ChIP-Seq_MCF-7_Human1.35370649
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.35201018
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33416497
65SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.33369007
66* CMYC_18555785_Chip-Seq_ESCs_Mouse1.32407739
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30807342
68CDX2_22108803_ChIP-Seq_LS180_Human1.30161107
69PCGF2_27294783_Chip-Seq_NPCs_Mouse1.29794704
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28532185
71STAT3_23295773_ChIP-Seq_U87_Human1.28438380
72* ETV1_20927104_ChIP-Seq_GIST48_Human1.26760495
73* E2F1_18555785_Chip-Seq_ESCs_Mouse1.26408800
74HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.26235717
75CBP_20019798_ChIP-Seq_JUKART_Human1.25711753
76IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25711753
77* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.25658174
78* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.24696084
79PRDM14_20953172_ChIP-Seq_ESCs_Human1.24258571
80PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.23910317
81FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.23354757
82* P300_18555785_Chip-Seq_ESCs_Mouse1.23248799
83KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23107145
84BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23057210
85FLI1_21867929_ChIP-Seq_TH2_Mouse1.22733489
86AR_20517297_ChIP-Seq_VCAP_Human1.21692201
87* STAT3_18555785_Chip-Seq_ESCs_Mouse1.19877325
88CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19862062
89* EZH2_27294783_Chip-Seq_NPCs_Mouse1.19462099
90RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.19039552
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18468172
92SUZ12_27294783_Chip-Seq_ESCs_Mouse1.18359929
93EZH2_27294783_Chip-Seq_ESCs_Mouse1.17687501
94* SOX2_18555785_Chip-Seq_ESCs_Mouse1.16681654
95* OCT4_18555785_Chip-Seq_ESCs_Mouse1.16647744
96EZH2_27304074_Chip-Seq_ESCs_Mouse1.16517881
97AR_25329375_ChIP-Seq_VCAP_Human1.16019986
98PHF8_20622853_ChIP-Seq_HELA_Human1.15949265
99CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.15762325
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15122577
101IGF1R_20145208_ChIP-Seq_DFB_Human1.14898834
102* RBPJ_21746931_ChIP-Seq_IB4_Human1.14745840
103JARID2_20064375_ChIP-Seq_MESCs_Mouse1.14634843
104GATA1_26923725_Chip-Seq_HPCs_Mouse1.14484044
105MTF2_20144788_ChIP-Seq_MESCs_Mouse1.14103262
106TBL1_22424771_ChIP-Seq_293T_Human1.14063334
107* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13873408
108ERG_20517297_ChIP-Seq_VCAP_Human1.13818115
109NCOR_22424771_ChIP-Seq_293T_Human1.13030203
110REST_18959480_ChIP-ChIP_MESCs_Mouse1.12978879
111NFYB_21822215_ChIP-Seq_K562_Human1.12904843
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11776335
113AHR_22903824_ChIP-Seq_MCF-7_Human1.11178959
114BCAT_22108803_ChIP-Seq_LS180_Human1.11104013
115SOX9_26525672_Chip-Seq_HEART_Mouse1.11017453
116SMRT_27268052_Chip-Seq_Bcells_Human1.09947181
117ELK4_26923725_Chip-Seq_MESODERM_Mouse1.09814929
118RNF2_27304074_Chip-Seq_ESCs_Mouse1.09791880
119GATA3_21878914_ChIP-Seq_MCF-7_Human1.09194813
120* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08553046
121SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.07238571
122ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06788742
123HNFA_21074721_ChIP-Seq_CACO-2_Human1.06202226
124SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.05447514
125* PU1_27457419_Chip-Seq_LIVER_Mouse1.05107963
126GABP_17652178_ChIP-ChIP_JURKAT_Human1.04783472
127NFYA_21822215_ChIP-Seq_K562_Human1.03285916
128* KLF4_18555785_Chip-Seq_ESCs_Mouse1.03255733
129* NMYC_18555785_Chip-Seq_ESCs_Mouse1.02790655
130* CRX_20693478_ChIP-Seq_RETINA_Mouse1.02762949
131MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.02156759
132DROSHA_22980978_ChIP-Seq_HELA_Human1.01948300
133* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01896764
134* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01793012
135CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.01766366
136* CBX2_22325352_ChIP-Seq_293T-Rex_Human1.01616067
137ARNT_22903824_ChIP-Seq_MCF-7_Human1.01474234
138PIAS1_25552417_ChIP-Seq_VCAP_Human1.01368177

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.58522477
2MP0008877_abnormal_DNA_methylation4.56665384
3MP0003698_abnormal_male_reproductive3.81131382
4MP0001929_abnormal_gametogenesis3.32506903
5MP0003880_abnormal_central_pattern3.15581412
6MP0004859_abnormal_synaptic_plasticity3.10003846
7MP0008875_abnormal_xenobiotic_pharmacok2.90008452
8MP0002736_abnormal_nociception_after2.43450117
9MP0001968_abnormal_touch/_nociception2.43093456
10MP0009046_muscle_twitch2.42205835
11MP0003195_calcinosis2.39329992
12MP0003635_abnormal_synaptic_transmissio2.35199788
13MP0001188_hyperpigmentation2.32656492
14MP0002735_abnormal_chemical_nociception2.26783046
15MP0002210_abnormal_sex_determination2.24826993
16MP0002653_abnormal_ependyma_morphology2.22353091
17MP0001984_abnormal_olfaction2.19048765
18MP0004270_analgesia2.16085174
19MP0009745_abnormal_behavioral_response2.09732194
20MP0004133_heterotaxia2.05387940
21MP0005423_abnormal_somatic_nervous2.04537722
22MP0002161_abnormal_fertility/fecundity2.00936267
23MP0002909_abnormal_adrenal_gland2.00818543
24MP0002572_abnormal_emotion/affect_behav1.94776903
25MP0002063_abnormal_learning/memory/cond1.92650735
26MP0003718_maternal_effect1.87781206
27MP0002064_seizures1.87131837
28MP0003787_abnormal_imprinting1.85508052
29MP0001145_abnormal_male_reproductive1.83954424
30MP0002272_abnormal_nervous_system1.80475810
31MP0002928_abnormal_bile_duct1.79931906
32MP0010386_abnormal_urinary_bladder1.72220272
33MP0000653_abnormal_sex_gland1.69160153
34MP0001486_abnormal_startle_reflex1.68110555
35MP0000778_abnormal_nervous_system1.67831644
36MP0001986_abnormal_taste_sensitivity1.64146955
37MP0004019_abnormal_vitamin_homeostasis1.63385232
38MP0005646_abnormal_pituitary_gland1.62531261
39MP0003183_abnormal_peptide_metabolism1.62232619
40MP0002277_abnormal_respiratory_mucosa1.58875244
41MP0008872_abnormal_physiological_respon1.58695138
42MP0002132_abnormal_respiratory_system1.57734946
43MP0001485_abnormal_pinna_reflex1.56877139
44MP0005084_abnormal_gallbladder_morpholo1.56791081
45MP0002734_abnormal_mechanical_nocicepti1.55354595
46MP0008789_abnormal_olfactory_epithelium1.55290388
47MP0002837_dystrophic_cardiac_calcinosis1.54119851
48MP0002067_abnormal_sensory_capabilities1.54031748
49MP0003136_yellow_coat_color1.52984315
50MP0005551_abnormal_eye_electrophysiolog1.42916522
51MP0000569_abnormal_digit_pigmentation1.41692348
52MP0001440_abnormal_grooming_behavior1.41238714
53MP0003283_abnormal_digestive_organ1.40294010
54MP0005377_hearing/vestibular/ear_phenot1.36088949
55MP0003878_abnormal_ear_physiology1.36088949
56MP0002160_abnormal_reproductive_system1.32748615
57MP0005220_abnormal_exocrine_pancreas1.31399819
58MP0001529_abnormal_vocalization1.31048398
59MP0000013_abnormal_adipose_tissue1.27340994
60MP0003252_abnormal_bile_duct1.26448466
61MP0000372_irregular_coat_pigmentation1.25719041
62MP0001501_abnormal_sleep_pattern1.25641868
63MP0001944_abnormal_pancreas_morphology1.22894503
64MP0002557_abnormal_social/conspecific_i1.22878012
65MP0003011_delayed_dark_adaptation1.19760904
66MP0005085_abnormal_gallbladder_physiolo1.18714647
67MP0005408_hypopigmentation1.17457454
68MP0002102_abnormal_ear_morphology1.17351411
69MP0002822_catalepsy1.17020136
70MP0005623_abnormal_meninges_morphology1.15549596
71MP0002184_abnormal_innervation1.15392471
72MP0004811_abnormal_neuron_physiology1.14999298
73MP0001970_abnormal_pain_threshold1.14170843
74MP0005409_darkened_coat_color1.13542206
75MP0009780_abnormal_chondrocyte_physiolo1.12969979
76MP0008569_lethality_at_weaning1.12912517
77MP0000955_abnormal_spinal_cord1.12316933
78MP0002693_abnormal_pancreas_physiology1.11468245
79MP0001756_abnormal_urination1.11258230
80MP0006276_abnormal_autonomic_nervous1.11121685
81MP0005636_abnormal_mineral_homeostasis1.11086667
82MP0002733_abnormal_thermal_nociception1.10736430
83MP0000383_abnormal_hair_follicle1.10489288
84MP0006072_abnormal_retinal_apoptosis1.10363529
85MP0005332_abnormal_amino_acid1.09682524
86MP0005310_abnormal_salivary_gland1.08541070
87MP0006036_abnormal_mitochondrial_physio1.07561374
88MP0002882_abnormal_neuron_morphology1.07430967
89MP0005394_taste/olfaction_phenotype1.04173180
90MP0005499_abnormal_olfactory_system1.04173180
91MP0005395_other_phenotype1.03343150
92MP0005253_abnormal_eye_physiology1.02228805
93MP0002163_abnormal_gland_morphology0.99762316
94MP0001764_abnormal_homeostasis0.98433160
95MP0005367_renal/urinary_system_phenotyp0.97456033
96MP0000516_abnormal_urinary_system0.97456033
97MP0000427_abnormal_hair_cycle0.95601288
98MP0004036_abnormal_muscle_relaxation0.95476267
99MP0001765_abnormal_ion_homeostasis0.95186673
100MP0003879_abnormal_hair_cell0.94984556
101MP0003646_muscle_fatigue0.94468860
102MP0004147_increased_porphyrin_level0.93596222
103MP0001502_abnormal_circadian_rhythm0.92944165
104MP0010678_abnormal_skin_adnexa0.91232916
105MP0004924_abnormal_behavior0.91204820
106MP0005386_behavior/neurological_phenoty0.91204820
107MP0002876_abnormal_thyroid_physiology0.90862652
108MP0005171_absent_coat_pigmentation0.90547248
109MP0005645_abnormal_hypothalamus_physiol0.89810147
110MP0002152_abnormal_brain_morphology0.88692200
111MP0005670_abnormal_white_adipose0.88639096
112MP0002229_neurodegeneration0.87410758
113MP0002638_abnormal_pupillary_reflex0.87064603
114MP0002066_abnormal_motor_capabilities/c0.86148688
115MP0003633_abnormal_nervous_system0.86145200
116MP0003890_abnormal_embryonic-extraembry0.86037014
117MP0003121_genomic_imprinting0.85894656
118MP0005075_abnormal_melanosome_morpholog0.85301266
119MP0003631_nervous_system_phenotype0.85051746
120MP0001963_abnormal_hearing_physiology0.84590031
121MP0010329_abnormal_lipoprotein_level0.84514115
122MP0001324_abnormal_eye_pigmentation0.84257019
123MP0006292_abnormal_olfactory_placode0.83620544
124MP0005174_abnormal_tail_pigmentation0.83266012
125MP0000015_abnormal_ear_pigmentation0.83113630
126MP0003122_maternal_imprinting0.82863095
127MP0004742_abnormal_vestibular_system0.82637513
128MP0002752_abnormal_somatic_nervous0.81697150
129MP0005365_abnormal_bile_salt0.80954761
130MP0001905_abnormal_dopamine_level0.77663527
131MP0004043_abnormal_pH_regulation0.73567489
132MP0000631_abnormal_neuroendocrine_gland0.73493535
133MP0003634_abnormal_glial_cell0.73335674
134MP0004134_abnormal_chest_morphology0.72144679
135MP0008995_early_reproductive_senescence0.71469724
136MP0004885_abnormal_endolymph0.68257830
137MP0003632_abnormal_nervous_system0.67889701
138MP0004142_abnormal_muscle_tone0.67070439
139MP0005195_abnormal_posterior_eye0.66963922
140MP0005389_reproductive_system_phenotype0.63739607
141MP0008058_abnormal_DNA_repair0.62934904
142MP0000920_abnormal_myelination0.61995786
143MP0003861_abnormal_nervous_system0.60326750
144MP0005379_endocrine/exocrine_gland_phen0.59462609
145MP0005647_abnormal_sex_gland0.58972657
146MP0002234_abnormal_pharynx_morphology0.57857870
147MP0004145_abnormal_muscle_electrophysio0.56252177
148MP0000026_abnormal_inner_ear0.55545552
149MP0002282_abnormal_trachea_morphology0.55207377

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.11310884
2Abnormal respiratory motile cilium morphology (HP:0005938)7.58520253
3Abnormal respiratory epithelium morphology (HP:0012253)7.58520253
4Abnormal ciliary motility (HP:0012262)7.24315732
5Rhinitis (HP:0012384)6.58381393
6Chronic bronchitis (HP:0004469)5.19011569
7Infertility (HP:0000789)4.47640147
8Nephronophthisis (HP:0000090)4.09348438
9Bronchiectasis (HP:0002110)3.60746353
10Nasal polyposis (HP:0100582)3.57442525
11Medial flaring of the eyebrow (HP:0010747)3.54665672
12Cerebellar dysplasia (HP:0007033)3.40982549
13Type II lissencephaly (HP:0007260)3.40873329
14Abnormality of midbrain morphology (HP:0002418)3.24659959
15Molar tooth sign on MRI (HP:0002419)3.24659959
16Abnormality of the renal medulla (HP:0100957)3.19488204
17Tubulointerstitial nephritis (HP:0001970)3.09761991
18Gait imbalance (HP:0002141)2.92099722
19Bronchitis (HP:0012387)2.84922107
20Focal motor seizures (HP:0011153)2.84536640
21Anterior segment dysgenesis (HP:0007700)2.80409956
22Congenital primary aphakia (HP:0007707)2.78921207
23Abnormality of the nasal mucosa (HP:0000433)2.71986617
24Bundle branch block (HP:0011710)2.70895740
25Abnormal rod and cone electroretinograms (HP:0008323)2.67150520
26Nephrogenic diabetes insipidus (HP:0009806)2.59129405
27Buphthalmos (HP:0000557)2.58244575
28Pancreatic fibrosis (HP:0100732)2.54290314
29Recurrent sinusitis (HP:0011108)2.50407981
30Chronic hepatic failure (HP:0100626)2.41229376
31Male pseudohermaphroditism (HP:0000037)2.37186117
32Anencephaly (HP:0002323)2.33800292
33Attenuation of retinal blood vessels (HP:0007843)2.32587148
34Postaxial foot polydactyly (HP:0001830)2.30292411
35True hermaphroditism (HP:0010459)2.29134512
36Progressive inability to walk (HP:0002505)2.28169682
37Furrowed tongue (HP:0000221)2.26084844
38Recurrent otitis media (HP:0000403)2.25054671
39Epileptic encephalopathy (HP:0200134)2.24439573
40Progressive cerebellar ataxia (HP:0002073)2.21674690
41Genital tract atresia (HP:0001827)2.21623347
42Aplasia/Hypoplasia of the brainstem (HP:0007362)2.21366355
43Hypoplasia of the brainstem (HP:0002365)2.21366355
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.20706605
45Bile duct proliferation (HP:0001408)2.20582578
46Abnormal biliary tract physiology (HP:0012439)2.20582578
47Supernumerary spleens (HP:0009799)2.19996097
48Male infertility (HP:0003251)2.19702713
49Bony spicule pigmentary retinopathy (HP:0007737)2.17879986
50Sclerocornea (HP:0000647)2.16638586
51Gaze-evoked nystagmus (HP:0000640)2.16028480
52Retinal dysplasia (HP:0007973)2.14975898
53Postaxial hand polydactyly (HP:0001162)2.14400028
54Febrile seizures (HP:0002373)2.14055593
55Fibular hypoplasia (HP:0003038)2.12268993
56Poor coordination (HP:0002370)2.10747034
57Vaginal atresia (HP:0000148)2.09448373
58Congenital hepatic fibrosis (HP:0002612)2.09447253
59Abnormality of macular pigmentation (HP:0008002)2.08845493
60Abnormality of the lower motor neuron (HP:0002366)2.06562351
61Decreased circulating renin level (HP:0003351)2.05588558
62Hyperactive renin-angiotensin system (HP:0000841)2.05226922
63Hyperventilation (HP:0002883)2.04428096
64Gonadotropin excess (HP:0000837)2.02822217
65Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.3449061
66Dynein arm defect of respiratory motile cilia (HP:0012255)10.0970449
67Absent/shortened dynein arms (HP:0200106)10.0970449
68Aplasia/Hypoplasia of the lens (HP:0008063)1.99961042
69Tubulointerstitial abnormality (HP:0001969)1.96509961
70Abnormality of the dental root (HP:0006486)1.94590510
71Taurodontia (HP:0000679)1.94590510
72Abnormality of permanent molar morphology (HP:0011071)1.94590510
73Prostate neoplasm (HP:0100787)1.91364120
74Lissencephaly (HP:0001339)1.89987854
75Aplasia/Hypoplasia of the tongue (HP:0010295)1.89958596
76Tubular atrophy (HP:0000092)1.85840711
77Abnormality of molar (HP:0011077)1.85057656
78Abnormality of molar morphology (HP:0011070)1.85057656
79Intestinal atresia (HP:0011100)1.85001384
80Hyperkalemia (HP:0002153)1.82534169
81Amyotrophic lateral sclerosis (HP:0007354)1.81332431
82Chronic sinusitis (HP:0011109)1.81049410
83Chronic otitis media (HP:0000389)1.80991977
84Inability to walk (HP:0002540)1.80801211
85Genetic anticipation (HP:0003743)1.79305477
86Abnormality of the dental pulp (HP:0006479)1.77496651
87Atonic seizures (HP:0010819)1.76925467
88Focal seizures (HP:0007359)1.76923607
89Oculomotor apraxia (HP:0000657)1.76273193
90Abnormality of ocular smooth pursuit (HP:0000617)1.75778135
91Pachygyria (HP:0001302)1.75076993
92Median cleft lip (HP:0000161)1.74704262
93Ketoacidosis (HP:0001993)1.72022661
94Abnormal spermatogenesis (HP:0008669)1.70577592
95Aplasia/Hypoplasia of the spleen (HP:0010451)1.66972533
96Congenital stationary night blindness (HP:0007642)1.65733983
97Cystic liver disease (HP:0006706)1.64102463
98Widely spaced teeth (HP:0000687)1.63481092
99Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.61966068
100Degeneration of the lateral corticospinal tracts (HP:0002314)1.61966068
101Mitochondrial inheritance (HP:0001427)1.61756271
102Asplenia (HP:0001746)1.60745453
103Stage 5 chronic kidney disease (HP:0003774)1.60396783
104Left ventricular hypertrophy (HP:0001712)1.59882019
105Hypokalemic alkalosis (HP:0001949)1.59801385
106Retinitis pigmentosa (HP:0000510)1.59517334
107Polydipsia (HP:0001959)1.59331723
108Abnormal drinking behavior (HP:0030082)1.59331723
109Impaired smooth pursuit (HP:0007772)1.59320197
110Specific learning disability (HP:0001328)1.58634460
111Severe visual impairment (HP:0001141)1.57580744
112Pancreatic cysts (HP:0001737)1.57013374
113Abolished electroretinogram (ERG) (HP:0000550)1.56011653
114Absent speech (HP:0001344)1.55254063
115Occipital encephalocele (HP:0002085)1.53313409
116Abnormality of the renal cortex (HP:0011035)1.51602892
117Acute necrotizing encephalopathy (HP:0006965)1.51193221
118Abnormal hair whorl (HP:0010721)1.51073560
119Hemiparesis (HP:0001269)1.50964422
120Progressive macrocephaly (HP:0004481)1.50941830
121Polyuria (HP:0000103)1.49255237
122Choroideremia (HP:0001139)1.49134354
123Meningocele (HP:0002435)1.48226966
124Disproportionate short-trunk short stature (HP:0003521)1.47726264
125Hepatic necrosis (HP:0002605)1.46650528
126Congenital glaucoma (HP:0001087)1.46498387
127Abnormality of dentin (HP:0010299)1.46363961
128Lipid accumulation in hepatocytes (HP:0006561)1.45205914
129Preaxial hand polydactyly (HP:0001177)1.44692399
130Hepatocellular necrosis (HP:0001404)1.42843960
131Decreased central vision (HP:0007663)1.42247018
132Short ribs (HP:0000773)1.42125494
133Abnormality of renal resorption (HP:0011038)1.42100747
134Recurrent bronchitis (HP:0002837)1.41963184
135Hyperaldosteronism (HP:0000859)1.40510828
136Abnormality of renin-angiotensin system (HP:0000847)1.39711133
137Hypoplasia of the fovea (HP:0007750)1.39345407
138Aplasia/Hypoplasia of the fovea (HP:0008060)1.39345407
139Abnormality of renal excretion (HP:0011036)1.38488918
140Ketosis (HP:0001946)1.38417961
1413-Methylglutaconic aciduria (HP:0003535)1.38021323
142Increased CSF lactate (HP:0002490)1.37913242
143Prominent nasal bridge (HP:0000426)1.37357509
144Methylmalonic acidemia (HP:0002912)1.36807381
145Renal Fanconi syndrome (HP:0001994)1.36450836

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.31478017
2PDK36.31478017
3MST44.31646511
4PIK3CG4.31233114
5PDK23.83298524
6CASK3.37313472
7EPHA42.57463422
8PRKD32.50650863
9MAP4K22.48215563
10NTRK32.25542937
11PNCK2.23021953
12MAP2K72.21199469
13PTK2B1.85099670
14RIPK41.74199432
15TNIK1.72883887
16NUAK11.71597196
17TESK11.63845064
18MARK11.59658689
19GRK11.59170923
20STK38L1.55255621
21MAP3K41.53960243
22AKT31.51863325
23STK391.51776791
24CCNB11.51213632
25WNK41.50856485
26ZAK1.49717477
27ACVR1B1.42897896
28NTRK21.39280824
29CDK191.35355144
30ICK1.28497077
31STK241.27051750
32ADRBK21.25234269
33MAPK151.18725908
34MAP3K21.17411754
35PLK21.16163645
36MAPK131.16152801
37MUSK1.15102971
38PRPF4B1.14177566
39SGK21.13526854
40MINK11.11381212
41BMPR1B1.10640443
42STK381.07553544
43SGK2230.96718722
44SGK4940.96718722
45WNK10.93898875
46STK160.93407542
47FRK0.92884136
48NLK0.90429374
49NME10.89438975
50TEC0.89312783
51TAOK30.88463659
52WNK30.88250044
53VRK10.85589903
54YES10.85102643
55TLK10.83388374
56PBK0.83047640
57MARK20.82527224
58KIT0.81337614
59PIK3CA0.79765076
60BRSK20.78075511
61MAP2K40.77911192
62SIK30.76569592
63PDK10.75043832
64TRIM280.74798218
65MAP3K120.74593919
66CAMK1G0.74483011
67CSNK1G10.71352536
68PRKCG0.69307553
69CAMK2A0.66506199
70PAK30.66504895
71BLK0.65925939
72CSNK1G20.65600138
73CLK10.65590776
74TNK20.64172197
75BRAF0.62532533
76PLK10.62313220
77CDK30.62069412
78SGK30.59957348
79ADRBK10.58902694
80PLK40.58347209
81DAPK20.58094099
82OXSR10.56318067
83TRPM70.56067497
84BMPR20.53544795
85FES0.53468108
86CSNK1G30.52646175
87PRKG10.52083186
88INSRR0.52055796
89CDK50.50408450
90TXK0.49157438
91STK30.48401453
92SGK10.48239625
93DYRK30.47800179
94CAMK2B0.46810063
95PRKAA20.46605919
96DAPK10.46497238
97PAK60.46111317
98CAMK1D0.45874621
99HIPK20.45043984
100IRAK10.44872763
101RPS6KA40.44374146
102NEK60.44298084
103ERBB40.44295011
104GRK50.43306051
105PRKCI0.43259024
106FER0.42728740
107PKN10.42536914
108ATM0.42437190
109RPS6KA50.42153449
110PINK10.42152160
111KSR10.41717354
112DYRK20.41295188
113BRD40.40185302
114PRKCH0.39665921
115FGFR20.38946889
116MYLK0.36698932
117ITK0.36166222
118PLK30.35652779
119BCR0.35348417
120CSNK1E0.35204400
121DYRK1A0.35172272
122ERBB20.35131175
123IKBKB0.35056132
124CSNK1D0.34334042
125MKNK20.33828457
126CAMK10.33585153
127CSNK1A10.33385720
128IRAK20.32265728
129MAP3K140.32119971
130PHKG20.31592651
131PHKG10.31592651
132ERBB30.30174268
133PRKCE0.29985544
134CDK180.29936119
135RPS6KB10.29443752
136CSF1R0.29339088
137CAMKK10.29241772
138PDPK10.28278960
139UHMK10.28087646
140PRKD20.27488307
141CDK150.24746983
142PRKCQ0.24682883
143PRKCB0.23126978
144PRKACB0.21771995
145CAMK2D0.21472925
146CDK11A0.21249951
147CAMKK20.21036063
148PASK0.20877204
149STK110.20779262
150SIK20.20456280
151PRKACA0.20245712

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.20138792
2Nicotine addiction_Homo sapiens_hsa050333.12126932
3Maturity onset diabetes of the young_Homo sapiens_hsa049503.10946392
4Oxidative phosphorylation_Homo sapiens_hsa001902.64297027
5Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.61391406
6Protein export_Homo sapiens_hsa030602.46314036
7Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.43804920
8Amphetamine addiction_Homo sapiens_hsa050312.39205627
9Chemical carcinogenesis_Homo sapiens_hsa052042.34606193
10Circadian entrainment_Homo sapiens_hsa047132.30429949
11Synaptic vesicle cycle_Homo sapiens_hsa047212.22601076
12Glutamatergic synapse_Homo sapiens_hsa047242.21017379
13Long-term potentiation_Homo sapiens_hsa047202.19762061
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.19005787
15Vitamin B6 metabolism_Homo sapiens_hsa007502.16161773
16Butanoate metabolism_Homo sapiens_hsa006502.14487278
17Olfactory transduction_Homo sapiens_hsa047402.07764796
18Caffeine metabolism_Homo sapiens_hsa002322.07741971
19Morphine addiction_Homo sapiens_hsa050321.98631734
20Taste transduction_Homo sapiens_hsa047421.95694583
21Parkinsons disease_Homo sapiens_hsa050121.94507484
22Regulation of autophagy_Homo sapiens_hsa041401.87094702
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.84051792
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.82236818
25Renin secretion_Homo sapiens_hsa049241.80752547
26Collecting duct acid secretion_Homo sapiens_hsa049661.80648810
27beta-Alanine metabolism_Homo sapiens_hsa004101.76865937
28GABAergic synapse_Homo sapiens_hsa047271.76725941
29Insulin secretion_Homo sapiens_hsa049111.70424529
30Dorso-ventral axis formation_Homo sapiens_hsa043201.67980336
31Carbohydrate digestion and absorption_Homo sapiens_hsa049731.66768561
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.65641810
33Histidine metabolism_Homo sapiens_hsa003401.64791287
34Retinol metabolism_Homo sapiens_hsa008301.64370216
35Calcium signaling pathway_Homo sapiens_hsa040201.56129885
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.54931192
37Dopaminergic synapse_Homo sapiens_hsa047281.53319332
38Peroxisome_Homo sapiens_hsa041461.49837175
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46780961
40Homologous recombination_Homo sapiens_hsa034401.44719346
41Glucagon signaling pathway_Homo sapiens_hsa049221.44027137
42Tryptophan metabolism_Homo sapiens_hsa003801.43696949
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.43355078
44Oocyte meiosis_Homo sapiens_hsa041141.41032211
45Phototransduction_Homo sapiens_hsa047441.39959048
46Alzheimers disease_Homo sapiens_hsa050101.39248100
47Type II diabetes mellitus_Homo sapiens_hsa049301.39214854
48Aldosterone synthesis and secretion_Homo sapiens_hsa049251.38602630
49Tyrosine metabolism_Homo sapiens_hsa003501.38423636
50Serotonergic synapse_Homo sapiens_hsa047261.34581382
51Cholinergic synapse_Homo sapiens_hsa047251.34424789
52Steroid hormone biosynthesis_Homo sapiens_hsa001401.33881601
53Salivary secretion_Homo sapiens_hsa049701.33675540
54Fatty acid degradation_Homo sapiens_hsa000711.33448467
55Cocaine addiction_Homo sapiens_hsa050301.33313775
56Oxytocin signaling pathway_Homo sapiens_hsa049211.32171604
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.30325305
58Nitrogen metabolism_Homo sapiens_hsa009101.28233361
59ABC transporters_Homo sapiens_hsa020101.27872003
60cAMP signaling pathway_Homo sapiens_hsa040241.27150333
61Glutathione metabolism_Homo sapiens_hsa004801.26428701
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.26089713
63Inositol phosphate metabolism_Homo sapiens_hsa005621.21669401
64Fanconi anemia pathway_Homo sapiens_hsa034601.20011983
65Phenylalanine metabolism_Homo sapiens_hsa003601.19480354
66cGMP-PKG signaling pathway_Homo sapiens_hsa040221.16892459
67Long-term depression_Homo sapiens_hsa047301.15787317
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.15786354
69Basal transcription factors_Homo sapiens_hsa030221.15355843
70RNA degradation_Homo sapiens_hsa030181.14917820
71RNA polymerase_Homo sapiens_hsa030201.13469513
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12738668
73Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.12150404
74Estrogen signaling pathway_Homo sapiens_hsa049151.12026895
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11614851
76Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.10740621
77Fatty acid biosynthesis_Homo sapiens_hsa000611.09915880
78Pyruvate metabolism_Homo sapiens_hsa006201.08951822
79Gastric acid secretion_Homo sapiens_hsa049711.08120450
80Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.05999736
81Arachidonic acid metabolism_Homo sapiens_hsa005901.04112494
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01787554
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99653439
84Axon guidance_Homo sapiens_hsa043600.99037537
85Proteasome_Homo sapiens_hsa030500.98389594
86Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.98094234
87Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.96208846
88Primary bile acid biosynthesis_Homo sapiens_hsa001200.92754572
89Purine metabolism_Homo sapiens_hsa002300.91657261
90Cardiac muscle contraction_Homo sapiens_hsa042600.88607364
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.88077338
92Huntingtons disease_Homo sapiens_hsa050160.88073199
93ErbB signaling pathway_Homo sapiens_hsa040120.87688382
94Vibrio cholerae infection_Homo sapiens_hsa051100.83707611
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.83540778
96Ether lipid metabolism_Homo sapiens_hsa005650.81639764
97Metabolic pathways_Homo sapiens_hsa011000.78703310
98Glioma_Homo sapiens_hsa052140.78056267
99Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76522079
100Linoleic acid metabolism_Homo sapiens_hsa005910.74308403
101Selenocompound metabolism_Homo sapiens_hsa004500.72996973
102Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72613888
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.71123619
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70431914
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69474909
106B cell receptor signaling pathway_Homo sapiens_hsa046620.67136181
107Ovarian steroidogenesis_Homo sapiens_hsa049130.66470195
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64814756
109Mineral absorption_Homo sapiens_hsa049780.64653381
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64494919
111VEGF signaling pathway_Homo sapiens_hsa043700.64457066
112Circadian rhythm_Homo sapiens_hsa047100.64076486
113Choline metabolism in cancer_Homo sapiens_hsa052310.62816056
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.62542891
115Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62252510
116Rheumatoid arthritis_Homo sapiens_hsa053230.61202857
117Ras signaling pathway_Homo sapiens_hsa040140.59104864
118Wnt signaling pathway_Homo sapiens_hsa043100.58925247
119MAPK signaling pathway_Homo sapiens_hsa040100.57584255
120Glycerolipid metabolism_Homo sapiens_hsa005610.57251577
121Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55833526
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54329152
123Mismatch repair_Homo sapiens_hsa034300.53185771
124Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.52917811
125Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52713561
126Gap junction_Homo sapiens_hsa045400.52455553
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52393166
128Nucleotide excision repair_Homo sapiens_hsa034200.52303114
129GnRH signaling pathway_Homo sapiens_hsa049120.51361439
130Asthma_Homo sapiens_hsa053100.51233800
131Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51175292
132Endometrial cancer_Homo sapiens_hsa052130.50927882
133Propanoate metabolism_Homo sapiens_hsa006400.48454987
134Fatty acid metabolism_Homo sapiens_hsa012120.48043816
135Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.47544858
136Glycerophospholipid metabolism_Homo sapiens_hsa005640.47276473
137Melanogenesis_Homo sapiens_hsa049160.46735829
138Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46570905
139mRNA surveillance pathway_Homo sapiens_hsa030150.46334506
140Pancreatic secretion_Homo sapiens_hsa049720.45862981
141Phospholipase D signaling pathway_Homo sapiens_hsa040720.45609287
142Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44407234
143Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44103293
144Melanoma_Homo sapiens_hsa052180.43661493
145Intestinal immune network for IgA production_Homo sapiens_hsa046720.43645037
146Renal cell carcinoma_Homo sapiens_hsa052110.42185918
147Sulfur metabolism_Homo sapiens_hsa009200.41930355
148Fatty acid elongation_Homo sapiens_hsa000620.41370553
149Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41035446
150Sphingolipid metabolism_Homo sapiens_hsa006000.40917095
151SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39108065
152Type I diabetes mellitus_Homo sapiens_hsa049400.38840770
153Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37150650
154Endocytosis_Homo sapiens_hsa041440.37006215
155Hedgehog signaling pathway_Homo sapiens_hsa043400.36963156
156Non-homologous end-joining_Homo sapiens_hsa034500.35813342
157Thyroid hormone synthesis_Homo sapiens_hsa049180.35742139
158Folate biosynthesis_Homo sapiens_hsa007900.33719333
159Cysteine and methionine metabolism_Homo sapiens_hsa002700.31497282
160Starch and sucrose metabolism_Homo sapiens_hsa005000.26761174

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