TSGA13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1omega-hydroxylase P450 pathway (GO:0097267)7.47312549
2presynaptic membrane assembly (GO:0097105)5.05464206
3pyrimidine ribonucleoside catabolic process (GO:0046133)4.99369775
4nucleoside diphosphate catabolic process (GO:0009134)4.63813442
5protein-cofactor linkage (GO:0018065)4.62012292
6behavioral response to nicotine (GO:0035095)4.54798181
7postsynaptic membrane organization (GO:0001941)4.40033352
8L-fucose catabolic process (GO:0042355)4.25600658
9fucose catabolic process (GO:0019317)4.25600658
10L-fucose metabolic process (GO:0042354)4.25600658
11presynaptic membrane organization (GO:0097090)4.15076179
12amino sugar catabolic process (GO:0046348)4.12270407
13protein heterotetramerization (GO:0051290)4.00267390
14response to pheromone (GO:0019236)3.91134097
15mesenchymal cell differentiation involved in renal system development (GO:2001012)3.78607830
16mesenchymal cell differentiation involved in kidney development (GO:0072161)3.78607830
17pyrimidine nucleotide catabolic process (GO:0006244)3.71330506
18regulation of timing of cell differentiation (GO:0048505)3.70876354
19short-term memory (GO:0007614)3.69252095
20response to folic acid (GO:0051593)3.63396567
21water-soluble vitamin biosynthetic process (GO:0042364)3.60417454
22cell wall macromolecule catabolic process (GO:0016998)3.56452276
23cell wall macromolecule metabolic process (GO:0044036)3.56452276
24DNA ligation (GO:0006266)3.56323128
25regulation of development, heterochronic (GO:0040034)3.56076751
26facial nerve structural organization (GO:0021612)3.55328687
27positive regulation of protein kinase C signaling (GO:0090037)3.52746551
28mannosylation (GO:0097502)3.51404525
29negative regulation of leukocyte chemotaxis (GO:0002689)3.51063003
30dopamine transport (GO:0015872)3.48210895
31regulation of pigment cell differentiation (GO:0050932)3.46406603
32piRNA metabolic process (GO:0034587)3.44497740
33cranial nerve morphogenesis (GO:0021602)3.41584978
34N-acetylneuraminate metabolic process (GO:0006054)3.41358798
35DNA deamination (GO:0045006)3.35437405
36sulfation (GO:0051923)3.33247467
37androgen biosynthetic process (GO:0006702)3.32436929
38melanin metabolic process (GO:0006582)3.32003367
39superoxide anion generation (GO:0042554)3.31625533
40indolalkylamine metabolic process (GO:0006586)3.29885877
41negative regulation of telomere maintenance (GO:0032205)3.26352495
42detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.25797060
43acrosome assembly (GO:0001675)3.25706621
44epithelial cilium movement (GO:0003351)3.24320705
45regulation of neurotransmitter uptake (GO:0051580)3.23930520
46mesonephros development (GO:0001823)3.22723241
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.21438358
48tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.21438358
49tryptophan catabolic process (GO:0006569)3.21434642
50indole-containing compound catabolic process (GO:0042436)3.21434642
51indolalkylamine catabolic process (GO:0046218)3.21434642
52kynurenine metabolic process (GO:0070189)3.20891041
53DNA double-strand break processing (GO:0000729)3.20396495
54multicellular organism reproduction (GO:0032504)3.19445053
55platelet dense granule organization (GO:0060155)3.19133786
56response to peptidoglycan (GO:0032494)3.17463554
57male meiosis (GO:0007140)3.17378346
58arginine metabolic process (GO:0006525)3.16440597
59negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)3.14552665
60protein complex biogenesis (GO:0070271)3.12422400
61cellular ketone body metabolic process (GO:0046950)3.11349626
62positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.11253797
63regulation of hexokinase activity (GO:1903299)3.08799924
64regulation of glucokinase activity (GO:0033131)3.08799924
65preassembly of GPI anchor in ER membrane (GO:0016254)3.06253458
66reflex (GO:0060004)3.05931938
67neuronal action potential (GO:0019228)3.02639700
68negative regulation of mast cell activation (GO:0033004)3.02370213
69cilium movement (GO:0003341)2.99064628
70viral transcription (GO:0019083)2.97338128
71cytochrome complex assembly (GO:0017004)2.97029890
72centriole assembly (GO:0098534)2.95674636
73oligosaccharide catabolic process (GO:0009313)2.95581890
74amine catabolic process (GO:0009310)2.95395629
75cellular biogenic amine catabolic process (GO:0042402)2.95395629
76cell differentiation involved in metanephros development (GO:0072202)2.95182953
77retinal cone cell development (GO:0046549)2.95098130
78cilium or flagellum-dependent cell motility (GO:0001539)2.93009941
79mitochondrial respiratory chain complex assembly (GO:0033108)2.91493208
80regulation of interleukin-6 biosynthetic process (GO:0045408)2.91191233
81tryptophan metabolic process (GO:0006568)2.90794120
82establishment of protein localization to mitochondrial membrane (GO:0090151)2.89577815
83mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.89486320
84mitochondrial respiratory chain complex I assembly (GO:0032981)2.89486320
85NADH dehydrogenase complex assembly (GO:0010257)2.89486320
86respiratory chain complex IV assembly (GO:0008535)2.89093726
87negative regulation of execution phase of apoptosis (GO:1900118)2.88460128
88ketone body metabolic process (GO:1902224)2.88028247
89axonemal dynein complex assembly (GO:0070286)2.87698587
90negative regulation of transcription by competitive promoter binding (GO:0010944)2.86936808
91generation of neurons (GO:0048699)2.84426426
92positive regulation of uterine smooth muscle contraction (GO:0070474)2.82054141
93DNA methylation involved in gamete generation (GO:0043046)2.82011999
94kidney morphogenesis (GO:0060993)2.81745994
95reciprocal DNA recombination (GO:0035825)2.81436834
96reciprocal meiotic recombination (GO:0007131)2.81436834
97negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80787879
98dendritic cell chemotaxis (GO:0002407)2.80484046
99specification of organ identity (GO:0010092)2.80479927
100transmission of nerve impulse (GO:0019226)2.79693007
101auditory receptor cell stereocilium organization (GO:0060088)2.78321336
102neural tube formation (GO:0001841)2.78292962
103gamma-aminobutyric acid transport (GO:0015812)2.77910647
104regulation of interleukin-8 secretion (GO:2000482)2.77569387
105protein K11-linked deubiquitination (GO:0035871)2.76493275
106cranial nerve structural organization (GO:0021604)2.75630107
107detection of light stimulus involved in visual perception (GO:0050908)2.75444854
108detection of light stimulus involved in sensory perception (GO:0050962)2.75444854
109forebrain neuron development (GO:0021884)2.74723002
110adaptation of signaling pathway (GO:0023058)2.71677418
111melanin biosynthetic process (GO:0042438)2.71631612
112rRNA catabolic process (GO:0016075)2.70497931
113translational termination (GO:0006415)2.69440795
114regulation of male gonad development (GO:2000018)2.69379951
115glycerophospholipid catabolic process (GO:0046475)2.69265922
116ribosomal small subunit assembly (GO:0000028)2.66912160
117mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.66829032
118G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.65436350
119regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.64801532
120regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.64801532
121regulation of meiosis I (GO:0060631)2.64664556
122somite rostral/caudal axis specification (GO:0032525)2.64111669
123pattern specification involved in kidney development (GO:0061004)2.63990272
124axoneme assembly (GO:0035082)2.63597879
125sympathetic nervous system development (GO:0048485)2.63458973
126cAMP catabolic process (GO:0006198)2.63289829
127photoreceptor cell maintenance (GO:0045494)2.63124958
128recombinational repair (GO:0000725)2.63064485
129RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.62529595
130developmental pigmentation (GO:0048066)2.62065648
131sperm capacitation (GO:0048240)2.61997600
132regulation of inositol phosphate biosynthetic process (GO:0010919)2.61117251
133GTP biosynthetic process (GO:0006183)2.61050359
134photoreceptor cell development (GO:0042461)2.60412395
135double-strand break repair via homologous recombination (GO:0000724)2.57823576
136ribosomal large subunit biogenesis (GO:0042273)2.57786187
137neuronal action potential propagation (GO:0019227)2.57658694
138indole-containing compound metabolic process (GO:0042430)2.56692417
139protein localization to cilium (GO:0061512)2.55620851
140ribosomal small subunit biogenesis (GO:0042274)2.55584937
141phosphatidylinositol acyl-chain remodeling (GO:0036149)2.55250047
142GPI anchor metabolic process (GO:0006505)2.54901807
143negative regulation of heart rate (GO:0010459)2.54791802
144cyclic nucleotide catabolic process (GO:0009214)2.54159266
145regulation of action potential (GO:0098900)2.53551919
146RNA destabilization (GO:0050779)2.53354054
147meiosis I (GO:0007127)2.53093881
148positive regulation of protein homodimerization activity (GO:0090073)2.51520269
149proteasome assembly (GO:0043248)2.51313644
150isoprenoid biosynthetic process (GO:0008299)2.50752882
151ubiquinone biosynthetic process (GO:0006744)2.50541537
152mature B cell differentiation (GO:0002335)2.50100277
153SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.49897653
154activated T cell proliferation (GO:0050798)2.49864474
155cornea development in camera-type eye (GO:0061303)2.48949755
156inner ear receptor stereocilium organization (GO:0060122)2.48376294
157adenosine metabolic process (GO:0046085)2.47543433
158nonmotile primary cilium assembly (GO:0035058)2.46847686
159female gonad development (GO:0008585)2.46318833
160sperm motility (GO:0030317)2.46276398
161cotranslational protein targeting to membrane (GO:0006613)2.44415688
162regulation of protein kinase C signaling (GO:0090036)2.43922155
163negative regulation of membrane potential (GO:0045837)2.43292998
164protein targeting to ER (GO:0045047)2.43220193
165nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.43188813
166behavioral response to ethanol (GO:0048149)2.41455990
167replication fork processing (GO:0031297)2.41440119
168viral genome replication (GO:0019079)2.41102238
169ubiquinone metabolic process (GO:0006743)2.40881690
170serotonin receptor signaling pathway (GO:0007210)2.40421679
171lymphoid progenitor cell differentiation (GO:0002320)2.40228573
172DNA damage response, detection of DNA damage (GO:0042769)2.40097726
173motile cilium assembly (GO:0044458)2.40061319
174acrosome reaction (GO:0007340)2.39404409
175cilium morphogenesis (GO:0060271)2.39364676
176sphingoid metabolic process (GO:0046519)2.38651637
177primary amino compound metabolic process (GO:1901160)2.38636124
178N-acetylglucosamine metabolic process (GO:0006044)2.38476019
179GMP metabolic process (GO:0046037)2.38414708
180positive regulation of monocyte chemotaxis (GO:0090026)2.38399796
181epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.38386686
182embryonic digestive tract morphogenesis (GO:0048557)2.35895293
183secondary metabolite biosynthetic process (GO:0044550)2.32351224
184positive regulation of calcium ion import (GO:0090280)2.31444523
185protein localization to endoplasmic reticulum (GO:0070972)2.26833588
186establishment of protein localization to endoplasmic reticulum (GO:0072599)2.26004355
187regulation of uterine smooth muscle contraction (GO:0070472)2.25881270
188spermatid nucleus differentiation (GO:0007289)2.25630620
189positive regulation of synaptic transmission, GABAergic (GO:0032230)2.25334778
190dendritic cell migration (GO:0036336)2.25046588
191reproduction (GO:0000003)2.24172572
192cellular response to exogenous dsRNA (GO:0071360)2.22690542

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.02207045
2ZNF274_21170338_ChIP-Seq_K562_Hela4.34602872
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.22031213
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.78940914
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.98508817
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.93755293
7GBX2_23144817_ChIP-Seq_PC3_Human2.87442309
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.75922763
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.75363515
10CBX2_27304074_Chip-Seq_ESCs_Mouse2.71396780
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.61035266
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.40518932
13BMI1_23680149_ChIP-Seq_NPCS_Mouse2.39224259
14SUZ12_27294783_Chip-Seq_NPCs_Mouse2.29745753
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.28233004
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.26711758
17JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23015110
18NFE2_27457419_Chip-Seq_LIVER_Mouse2.22949599
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.11434951
20PCGF2_27294783_Chip-Seq_NPCs_Mouse2.07206573
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.05582104
22EWS_26573619_Chip-Seq_HEK293_Human2.03421379
23FUS_26573619_Chip-Seq_HEK293_Human2.00683906
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.00141215
25RNF2_27304074_Chip-Seq_NSC_Mouse1.96879591
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.94047862
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.87756803
28SUZ12_18555785_Chip-Seq_ESCs_Mouse1.85440631
29EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.85340418
30EZH2_27294783_Chip-Seq_NPCs_Mouse1.84309477
31P53_22387025_ChIP-Seq_ESCs_Mouse1.81008074
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.79704038
33STAT3_18555785_Chip-Seq_ESCs_Mouse1.78494673
34P300_18555785_Chip-Seq_ESCs_Mouse1.78242380
35NMYC_18555785_Chip-Seq_ESCs_Mouse1.77546717
36EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.76742277
37SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.76495683
38RUNX1_27457419_Chip-Seq_LIVER_Mouse1.74667950
39E2F1_18555785_Chip-Seq_ESCs_Mouse1.74526568
40TP53_22573176_ChIP-Seq_HFKS_Human1.74214537
41NANOG_18555785_Chip-Seq_ESCs_Mouse1.73935210
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.73292511
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.73155448
44GABP_17652178_ChIP-ChIP_JURKAT_Human1.72699999
45JARID2_20075857_ChIP-Seq_MESCs_Mouse1.72152382
46CDX2_19796622_ChIP-Seq_MESCs_Mouse1.71804887
47NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.70272184
48TAF15_26573619_Chip-Seq_HEK293_Human1.70222130
49SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.69319396
50CBP_20019798_ChIP-Seq_JUKART_Human1.63905395
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.63905395
52CMYC_18555785_Chip-Seq_ESCs_Mouse1.59641029
53SOX2_18555785_Chip-Seq_ESCs_Mouse1.58229880
54OCT4_18555785_Chip-Seq_ESCs_Mouse1.57881385
55RNF2_18974828_ChIP-Seq_MESCs_Mouse1.57318345
56EZH2_18974828_ChIP-Seq_MESCs_Mouse1.57318345
57SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.55879451
58SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.55052959
59ESRRB_18555785_Chip-Seq_ESCs_Mouse1.54994054
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54545186
61KLF4_18555785_Chip-Seq_ESCs_Mouse1.54225465
62BCAT_22108803_ChIP-Seq_LS180_Human1.54030721
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.53160841
64* EZH2_27294783_Chip-Seq_ESCs_Mouse1.53136804
65CTCF_18555785_Chip-Seq_ESCs_Mouse1.51882851
66ZFX_18555785_Chip-Seq_ESCs_Mouse1.50981020
67AR_25329375_ChIP-Seq_VCAP_Human1.50045006
68POU5F1_16153702_ChIP-ChIP_HESCs_Human1.50028488
69FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.49902063
70PU1_27457419_Chip-Seq_LIVER_Mouse1.49653501
71VDR_22108803_ChIP-Seq_LS180_Human1.49367210
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47666798
73MYC_18940864_ChIP-ChIP_HL60_Human1.47648394
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.47051366
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.46472166
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.45551872
77IGF1R_20145208_ChIP-Seq_DFB_Human1.45467096
78SMAD1_18555785_Chip-Seq_ESCs_Mouse1.43962240
79CRX_20693478_ChIP-Seq_RETINA_Mouse1.43952309
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43907634
81AR_21572438_ChIP-Seq_LNCaP_Human1.40367021
82SMAD_19615063_ChIP-ChIP_OVARY_Human1.40052691
83POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39820582
84SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.39158605
85TAL1_26923725_Chip-Seq_HPCs_Mouse1.38677959
86ER_23166858_ChIP-Seq_MCF-7_Human1.37355440
87* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.37127581
88* FOXA1_25329375_ChIP-Seq_VCAP_Human1.37100243
89* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.37100243
90EST1_17652178_ChIP-ChIP_JURKAT_Human1.37017715
91* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34995565
92TCF4_22108803_ChIP-Seq_LS180_Human1.33650502
93P300_19829295_ChIP-Seq_ESCs_Human1.33593813
94STAT3_23295773_ChIP-Seq_U87_Human1.33454130
95GATA3_21878914_ChIP-Seq_MCF-7_Human1.32919840
96TCF4_23295773_ChIP-Seq_U87_Human1.32252007
97RNF2_27304074_Chip-Seq_ESCs_Mouse1.31954805
98CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31694910
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31215335
100SALL1_21062744_ChIP-ChIP_HESCs_Human1.30352711
101IKZF1_21737484_ChIP-ChIP_HCT116_Human1.29306890
102IRF8_22096565_ChIP-ChIP_GC-B_Human1.29162160
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29035208
104CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25728779
105OCT4_21477851_ChIP-Seq_ESCs_Mouse1.24470872
106NCOR_22424771_ChIP-Seq_293T_Human1.24275774
107REST_21632747_ChIP-Seq_MESCs_Mouse1.24089402
108SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.23649422
109* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.23404944
110SOX2_19829295_ChIP-Seq_ESCs_Human1.22971838
111NANOG_19829295_ChIP-Seq_ESCs_Human1.22971838
112CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21156892
113* RUNX2_22187159_ChIP-Seq_PCA_Human1.20120354
114NR3C1_21868756_ChIP-Seq_MCF10A_Human1.19998735
115PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18794836
116VDR_23849224_ChIP-Seq_CD4+_Human1.17728400
117CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16959322
118IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.16750967
119SMAD4_21741376_ChIP-Seq_EPCs_Human1.16311713
120LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16230883
121LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.15522891
122HOXB7_26014856_ChIP-Seq_BT474_Human1.15522450
123SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.14123744
124FLI1_21867929_ChIP-Seq_TH2_Mouse1.11991892
125AR_20517297_ChIP-Seq_VCAP_Human1.11542087
126MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10554330
127IRF1_19129219_ChIP-ChIP_H3396_Human1.10083246
128PRDM14_20953172_ChIP-Seq_ESCs_Human1.08427596
129ELK1_19687146_ChIP-ChIP_HELA_Human1.08421937
130IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.08390669
131SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.07948445
132CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.07250355
133SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07053365
134AUTS2_25519132_ChIP-Seq_293T-REX_Human1.06715703
135RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06513336
136KDM2B_26808549_Chip-Seq_REH_Human1.05122205
137SMAD3_21741376_ChIP-Seq_EPCs_Human1.05113818
138KAP1_22055183_ChIP-Seq_ESCs_Mouse1.04120658
139* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03057866
140PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.02655051
141ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.01536420
142CTBP1_25329375_ChIP-Seq_LNCAP_Human1.01485989
143EGR1_23403033_ChIP-Seq_LIVER_Mouse1.01233462
144PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01099807
145CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00976103
146FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99246598
147TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98581474
148MYC_19829295_ChIP-Seq_ESCs_Human0.98472081
149NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97012582
150MTF2_20144788_ChIP-Seq_MESCs_Mouse0.96044780
151IRF8_21731497_ChIP-ChIP_J774_Mouse0.92675368
152PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.89599871
153* STAT1_17558387_ChIP-Seq_HELA_Human0.88707752
154TP53_18474530_ChIP-ChIP_U2OS_Human0.88659093
155PIAS1_25552417_ChIP-Seq_VCAP_Human0.87939935
156SMAD4_21799915_ChIP-Seq_A2780_Human0.87723301
157TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87062259
158POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87062259
159ETV2_25802403_ChIP-Seq_MESCs_Mouse0.86883775
160GATA3_21867929_ChIP-Seq_CD8_Mouse0.86743080
161PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.86078936

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.82160427
2MP0001188_hyperpigmentation4.47853620
3MP0005409_darkened_coat_color4.45443502
4MP0009379_abnormal_foot_pigmentation4.15043343
5MP0006292_abnormal_olfactory_placode3.93231580
6MP0008877_abnormal_DNA_methylation3.38964012
7MP0004381_abnormal_hair_follicle3.36121297
8MP0003195_calcinosis2.82046669
9MP0000566_synostosis2.74559060
10MP0005174_abnormal_tail_pigmentation2.64753588
11MP0000015_abnormal_ear_pigmentation2.62532367
12MP0002102_abnormal_ear_morphology2.52886391
13MP0003724_increased_susceptibility_to2.52040108
14MP0001986_abnormal_taste_sensitivity2.45850681
15MP0008872_abnormal_physiological_respon2.39203518
16MP0002837_dystrophic_cardiac_calcinosis2.34061813
17MP0006072_abnormal_retinal_apoptosis2.33833474
18MP0000372_irregular_coat_pigmentation2.17353718
19MP0003283_abnormal_digestive_organ2.09135356
20MP0002277_abnormal_respiratory_mucosa2.03687669
21MP0003880_abnormal_central_pattern2.00357054
22MP0008875_abnormal_xenobiotic_pharmacok1.95245914
23MP0003787_abnormal_imprinting1.94890526
24MP0001501_abnormal_sleep_pattern1.93311062
25MP0008260_abnormal_autophagy1.90333898
26MP0002876_abnormal_thyroid_physiology1.89965553
27MP0005171_absent_coat_pigmentation1.89072546
28MP0000569_abnormal_digit_pigmentation1.88834979
29MP0004885_abnormal_endolymph1.86561008
30MP0002736_abnormal_nociception_after1.86185789
31MP0004043_abnormal_pH_regulation1.73575133
32MP0001485_abnormal_pinna_reflex1.72288819
33MP0004133_heterotaxia1.66386635
34MP0002272_abnormal_nervous_system1.63323196
35MP0005410_abnormal_fertilization1.58143658
36MP0003315_abnormal_perineum_morphology1.56349577
37MP0003938_abnormal_ear_development1.53024763
38MP0002160_abnormal_reproductive_system1.51086467
39MP0002148_abnormal_hypersensitivity_rea1.50491312
40MP0002095_abnormal_skin_pigmentation1.49596371
41MP0002638_abnormal_pupillary_reflex1.49386502
42MP0001529_abnormal_vocalization1.48714479
43MP0002653_abnormal_ependyma_morphology1.47953485
44MP0009785_altered_susceptibility_to1.45738611
45MP0002138_abnormal_hepatobiliary_system1.43157968
46MP0003011_delayed_dark_adaptation1.42231574
47MP0001835_abnormal_antigen_presentation1.39982529
48MP0002064_seizures1.39979997
49MP0002249_abnormal_larynx_morphology1.39011075
50MP0000049_abnormal_middle_ear1.38826339
51MP0002177_abnormal_outer_ear1.37508070
52MP0003646_muscle_fatigue1.35974630
53MP0002938_white_spotting1.33102899
54MP0001984_abnormal_olfaction1.29981271
55MP0006276_abnormal_autonomic_nervous1.29567292
56MP0004145_abnormal_muscle_electrophysio1.26873446
57MP0000681_abnormal_thyroid_gland1.26431664
58MP0005257_abnormal_intraocular_pressure1.26307003
59MP0005167_abnormal_blood-brain_barrier1.24704042
60MP0005084_abnormal_gallbladder_morpholo1.24390014
61MP0000026_abnormal_inner_ear1.24365951
62MP0002572_abnormal_emotion/affect_behav1.22422079
63MP0002909_abnormal_adrenal_gland1.22142090
64MP0000427_abnormal_hair_cycle1.21817719
65MP0001968_abnormal_touch/_nociception1.21505385
66MP0005075_abnormal_melanosome_morpholog1.20671720
67MP0001919_abnormal_reproductive_system1.20665851
68MP0001764_abnormal_homeostasis1.19442784
69MP0001502_abnormal_circadian_rhythm1.19408293
70MP0002132_abnormal_respiratory_system1.18567857
71MP0002928_abnormal_bile_duct1.14809366
72MP0002751_abnormal_autonomic_nervous1.14640948
73MP0004742_abnormal_vestibular_system1.13630587
74MP0005386_behavior/neurological_phenoty1.12412335
75MP0004924_abnormal_behavior1.12412335
76MP0004147_increased_porphyrin_level1.11936082
77MP0009250_abnormal_appendicular_skeleto1.10790901
78MP0002733_abnormal_thermal_nociception1.09390492
79MP0005645_abnormal_hypothalamus_physiol1.06887044
80MP0000383_abnormal_hair_follicle1.06831076
81MP0004215_abnormal_myocardial_fiber1.05271191
82MP0005000_abnormal_immune_tolerance1.05167728
83MP0003635_abnormal_synaptic_transmissio1.04012545
84MP0000631_abnormal_neuroendocrine_gland1.03419066
85MP0005671_abnormal_response_to1.03253889
86MP0000613_abnormal_salivary_gland1.02172316
87MP0002693_abnormal_pancreas_physiology1.01947698
88MP0002009_preneoplasia1.01719482
89MP0001970_abnormal_pain_threshold1.00565178
90MP0005195_abnormal_posterior_eye1.00275222
91MP0005332_abnormal_amino_acid1.00131661
92MP0002557_abnormal_social/conspecific_i0.99731197
93MP0002163_abnormal_gland_morphology0.99665416
94MP0004142_abnormal_muscle_tone0.98603536
95MP0003121_genomic_imprinting0.98432249
96MP0003786_premature_aging0.96378451
97MP0005025_abnormal_response_to0.96150122
98MP0005220_abnormal_exocrine_pancreas0.94677935
99MP0002735_abnormal_chemical_nociception0.92187059
100MP0000230_abnormal_systemic_arterial0.91946070
101MP0002063_abnormal_learning/memory/cond0.91784279
102MP0003941_abnormal_skin_development0.91735062
103MP0005389_reproductive_system_phenotype0.90861896
104MP0005379_endocrine/exocrine_gland_phen0.89654430
105MP0003436_decreased_susceptibility_to0.89566700
106MP0003698_abnormal_male_reproductive0.88084370
107MP0003303_peritoneal_inflammation0.87836592
108MP0003763_abnormal_thymus_physiology0.86851755
109MP0001486_abnormal_startle_reflex0.86705016
110MP0003878_abnormal_ear_physiology0.86373134
111MP0005377_hearing/vestibular/ear_phenot0.86373134
112MP0010329_abnormal_lipoprotein_level0.86093326
113MP0008995_early_reproductive_senescence0.85549041
114MP0002752_abnormal_somatic_nervous0.85387785
115MP0002229_neurodegeneration0.84712095
116MP0005448_abnormal_energy_balance0.84202101
117MP0002419_abnormal_innate_immunity0.83906403
118MP0002210_abnormal_sex_determination0.83880086
119MP0008775_abnormal_heart_ventricle0.83806388
120MP0001944_abnormal_pancreas_morphology0.83699366
121MP0003385_abnormal_body_wall0.82964605
122MP0001963_abnormal_hearing_physiology0.82529908
123MP0002067_abnormal_sensory_capabilities0.82435500
124MP0001324_abnormal_eye_pigmentation0.82029017
125MP0008789_abnormal_olfactory_epithelium0.79850456
126MP0000778_abnormal_nervous_system0.79276922
127MP0001663_abnormal_digestive_system0.78385749
128MP0003252_abnormal_bile_duct0.78346389
129MP0005085_abnormal_gallbladder_physiolo0.77667321
130MP0001346_abnormal_lacrimal_gland0.77039305
131MP0009046_muscle_twitch0.76133563
132MP0002234_abnormal_pharynx_morphology0.75575076
133MP0001664_abnormal_digestion0.74426895
134MP0005646_abnormal_pituitary_gland0.74189049
135MP0001186_pigmentation_phenotype0.74018995
136MP0009745_abnormal_behavioral_response0.72623529
137MP0002723_abnormal_immune_serum0.71893187
138MP0002452_abnormal_antigen_presenting0.71752489
139MP0010386_abnormal_urinary_bladder0.71458084
140MP0001800_abnormal_humoral_immune0.71444042
141MP0000490_abnormal_crypts_of0.70116592
142MP0003718_maternal_effect0.69392228
143MP0009764_decreased_sensitivity_to0.69379199
144MP0001819_abnormal_immune_cell0.68718203
145MP0002420_abnormal_adaptive_immunity0.67131044
146MP0005253_abnormal_eye_physiology0.66371723
147MP0005595_abnormal_vascular_smooth0.66150320
148MP0000579_abnormal_nail_morphology0.65406426
149MP0005387_immune_system_phenotype0.65030781
150MP0001790_abnormal_immune_system0.65030781
151MP0008058_abnormal_DNA_repair0.64793572
152MP0005381_digestive/alimentary_phenotyp0.64727882
153MP0001905_abnormal_dopamine_level0.64371898
154MP0001929_abnormal_gametogenesis0.64310635
155MP0009333_abnormal_splenocyte_physiolog0.62656131
156MP0005165_increased_susceptibility_to0.61824397
157MP0005551_abnormal_eye_electrophysiolog0.61520933
158MP0003879_abnormal_hair_cell0.60943290

Predicted human phenotypes

RankGene SetZ-score
1Type II lissencephaly (HP:0007260)5.31707469
2Congenital stationary night blindness (HP:0007642)4.25670507
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.91397256
4Reduced antithrombin III activity (HP:0001976)3.89941132
5Retinal dysplasia (HP:0007973)3.89896611
6Type I transferrin isoform profile (HP:0003642)3.77934880
7Dynein arm defect of respiratory motile cilia (HP:0012255)3.77515815
8Absent/shortened dynein arms (HP:0200106)3.77515815
9Abnormality of midbrain morphology (HP:0002418)3.57339444
10Molar tooth sign on MRI (HP:0002419)3.57339444
11Abnormal ciliary motility (HP:0012262)3.40597070
12Sex reversal (HP:0012245)3.37275331
13Abnormal sex determination (HP:0012244)3.37275331
14Abolished electroretinogram (ERG) (HP:0000550)3.08035552
15Abnormality of the renal cortex (HP:0011035)3.07407929
16Abnormal respiratory motile cilium physiology (HP:0012261)3.04034659
17Abnormal respiratory epithelium morphology (HP:0012253)2.98458848
18Abnormal respiratory motile cilium morphology (HP:0005938)2.98458848
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.95836232
20Chromosomal breakage induced by crosslinking agents (HP:0003221)2.94321020
21Optic nerve hypoplasia (HP:0000609)2.91124668
22Pendular nystagmus (HP:0012043)2.90078474
23Lissencephaly (HP:0001339)2.82475990
24Cerebellar dysplasia (HP:0007033)2.77085738
25Reticulocytopenia (HP:0001896)2.76388616
263-Methylglutaconic aciduria (HP:0003535)2.76209304
27Aplasia/Hypoplasia of the sacrum (HP:0008517)2.74433222
28Dry hair (HP:0011359)2.74384779
29Polydipsia (HP:0001959)2.73868568
30Abnormal drinking behavior (HP:0030082)2.73868568
31Abnormality of secondary sexual hair (HP:0009888)2.70570524
32Abnormality of the axillary hair (HP:0100134)2.70570524
33Large for gestational age (HP:0001520)2.69025061
34Inability to walk (HP:0002540)2.63822294
35Thyroid-stimulating hormone excess (HP:0002925)2.63770119
36Abnormal rod and cone electroretinograms (HP:0008323)2.61671974
37Congenital sensorineural hearing impairment (HP:0008527)2.59888925
38Absent rod-and cone-mediated responses on ERG (HP:0007688)2.58947974
39Optic disc pallor (HP:0000543)2.58512355
40Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.58456806
41Chronic obstructive pulmonary disease (HP:0006510)2.58185456
42Obstructive lung disease (HP:0006536)2.58185456
43Attenuation of retinal blood vessels (HP:0007843)2.57958456
44Stomatitis (HP:0010280)2.56336979
45Hypoplasia of the fovea (HP:0007750)2.53844802
46Aplasia/Hypoplasia of the fovea (HP:0008060)2.53844802
47Hyperventilation (HP:0002883)2.53430291
48Chromsome breakage (HP:0040012)2.52646972
49Acute necrotizing encephalopathy (HP:0006965)2.51427705
50Methylmalonic acidemia (HP:0002912)2.51154303
51Abnormality of the phalanges of the hallux (HP:0010057)2.50287489
52Clubbing of toes (HP:0100760)2.49819274
53Renal cortical cysts (HP:0000803)2.48564549
54True hermaphroditism (HP:0010459)2.48488131
55Nonprogressive disorder (HP:0003680)2.43363792
56Hypothermia (HP:0002045)2.42538757
57Renal Fanconi syndrome (HP:0001994)2.41350026
58Progressive macrocephaly (HP:0004481)2.38665609
59Short tibia (HP:0005736)2.38277590
60Anterior segment dysgenesis (HP:0007700)2.37656761
61Aplasia/Hypoplasia of the tibia (HP:0005772)2.36111161
62Capillary hemangiomas (HP:0005306)2.35792755
63Septo-optic dysplasia (HP:0100842)2.35567372
64Tubular atrophy (HP:0000092)2.35163102
65Meckel diverticulum (HP:0002245)2.32871507
66Abnormality of the preputium (HP:0100587)2.31873785
67Cystic liver disease (HP:0006706)2.30455062
68Absent septum pellucidum (HP:0001331)2.30370856
69Aplasia/Hypoplasia of the uvula (HP:0010293)2.28681806
70Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.28330415
71Increased CSF lactate (HP:0002490)2.27950775
72Congenital, generalized hypertrichosis (HP:0004540)2.27780014
73Abnormality of renal resorption (HP:0011038)2.27618901
74Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.27408092
75Abnormality of alanine metabolism (HP:0010916)2.27408092
76Hyperalaninemia (HP:0003348)2.27408092
77Acute encephalopathy (HP:0006846)2.27152785
78Sclerocornea (HP:0000647)2.26844180
79Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.26405441
80Abnormal protein N-linked glycosylation (HP:0012347)2.26405441
81Abnormal protein glycosylation (HP:0012346)2.26405441
82Abnormal glycosylation (HP:0012345)2.26405441
83Methylmalonic aciduria (HP:0012120)2.25428153
84Meningitis (HP:0001287)2.25018590
85Triphalangeal thumb (HP:0001199)2.24894432
86Progressive inability to walk (HP:0002505)2.24642322
87Abnormality of the ileum (HP:0001549)2.23861738
88Increased hepatocellular lipid droplets (HP:0006565)2.23722974
89Polyuria (HP:0000103)2.22232896
90Abnormal biliary tract physiology (HP:0012439)2.20855340
91Bile duct proliferation (HP:0001408)2.20855340
92Increased corneal curvature (HP:0100692)2.19155248
93Keratoconus (HP:0000563)2.19155248
94Gaze-evoked nystagmus (HP:0000640)2.19118383
95Decreased electroretinogram (ERG) amplitude (HP:0000654)2.18925648
96Hepatic necrosis (HP:0002605)2.18784666
97Stage 5 chronic kidney disease (HP:0003774)2.18530207
98Supernumerary spleens (HP:0009799)2.17604211
99Aplasia/hypoplasia of the uterus (HP:0008684)2.17596506
100Furrowed tongue (HP:0000221)2.17502911
101Abnormality of the septum pellucidum (HP:0007375)2.17223130
102Dyschromatopsia (HP:0007641)2.15595899
103Agitation (HP:0000713)2.15030233
104Hepatocellular necrosis (HP:0001404)2.14955465
105Abnormality of magnesium homeostasis (HP:0004921)2.14864041
106Decreased central vision (HP:0007663)2.14734024
107Amelogenesis imperfecta (HP:0000705)2.14661581
108Hypoplasia of the radius (HP:0002984)2.14628807
109Chronic hepatic failure (HP:0100626)2.13659438
110Ketoacidosis (HP:0001993)2.13504919
111Broad-based gait (HP:0002136)2.09434853
112Abnormal mitochondria in muscle tissue (HP:0008316)2.09259287
113Absent thumb (HP:0009777)2.08443821
114Microvesicular hepatic steatosis (HP:0001414)2.06247721
115Pachygyria (HP:0001302)2.05571739
116Focal motor seizures (HP:0011153)2.04616985
117Partial agenesis of the corpus callosum (HP:0001338)2.04543821
118Recurrent cutaneous fungal infections (HP:0011370)2.04030079
119Chronic mucocutaneous candidiasis (HP:0002728)2.04030079
120Hemiparesis (HP:0001269)2.02354689
121Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.01346501
122Nephronophthisis (HP:0000090)2.01276632
123Rhinitis (HP:0012384)2.00412300
124Tubulointerstitial nephritis (HP:0001970)1.99628991
125Oligodactyly (hands) (HP:0001180)1.98585892
126Gait imbalance (HP:0002141)1.98310223
127Aplasia/Hypoplasia of the tongue (HP:0010295)1.98277380
128Median cleft lip (HP:0000161)1.95861059
129Duplicated collecting system (HP:0000081)1.94637912
130Exertional dyspnea (HP:0002875)1.94566566
131Basal ganglia calcification (HP:0002135)1.94329297
132Abnormality of the renal collecting system (HP:0004742)1.94125930
133Aplasia cutis congenita (HP:0001057)1.94075876
134Retrobulbar optic neuritis (HP:0100654)1.93181291
135Optic neuritis (HP:0100653)1.93181291
136Pancreatic fibrosis (HP:0100732)1.93036648
137Medial flaring of the eyebrow (HP:0010747)1.92995494
138Stomach cancer (HP:0012126)1.91977013
139Patchy hypopigmentation of hair (HP:0011365)1.91922408
140Progressive microcephaly (HP:0000253)1.90792722
141Fair hair (HP:0002286)1.89660909
142Concave nail (HP:0001598)1.89489548
143Hypoproteinemia (HP:0003075)1.89373245
144Abnormality of the renal medulla (HP:0100957)1.89256402
145Hypomagnesemia (HP:0002917)1.88756994
146Congenital primary aphakia (HP:0007707)1.88329948
147Ketosis (HP:0001946)1.87562688
148Severe muscular hypotonia (HP:0006829)1.87150482
149Male pseudohermaphroditism (HP:0000037)1.86971986
150Pancreatic cysts (HP:0001737)1.86093180
151Absent speech (HP:0001344)1.86025433
152Nephrogenic diabetes insipidus (HP:0009806)1.84639099
153Recurrent abscess formation (HP:0002722)1.84536979
154White forelock (HP:0002211)1.83565994
155Congenital hepatic fibrosis (HP:0002612)1.83362819
156Renal dysplasia (HP:0000110)1.82640430
157Split foot (HP:0001839)1.81956525
158Agammaglobulinemia (HP:0004432)1.81527057
159Increased serum lactate (HP:0002151)1.81499555
160Mitochondrial inheritance (HP:0001427)1.81130571
161Abnormality of the pons (HP:0007361)1.81082444
162Tachypnea (HP:0002789)1.80952984
163Duplication of thumb phalanx (HP:0009942)1.80879711
164Abnormality of B cell number (HP:0010975)1.80832495
165Hyperglycinuria (HP:0003108)1.78561047
166Hypoplasia of the pons (HP:0012110)1.77797736
167Hypoplasia of the uterus (HP:0000013)1.77355515
168Abnormality of vitamin B metabolism (HP:0004340)1.75800278
169Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.74508295
170Clumsiness (HP:0002312)1.74111277
171Abnormal urine output (HP:0012590)1.73839366
172Biliary tract neoplasm (HP:0100574)1.73321572
173Hyperglycinemia (HP:0002154)1.73310845
174Progressive cerebellar ataxia (HP:0002073)1.71847550
175Abnormality of the vitreous humor (HP:0004327)1.71586285

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK6.29172285
2FRK4.85802544
3MKNK24.10573620
4NME23.72963002
5TLK13.63334463
6TNIK3.33263951
7MAP4K23.22380100
8IRAK32.77662585
9CLK12.56374849
10BLK2.30166670
11IRAK42.29990022
12MKNK12.24262122
13ACVR1B2.20666983
14PRPF4B2.19914472
15WNK32.15533718
16STK162.04061056
17TAOK31.95779140
18MAPK131.81026514
19IRAK11.78076989
20TXK1.72191649
21FES1.71246079
22MAP2K71.65476138
23NLK1.64806157
24TGFBR11.53271049
25YES11.53095980
26SRPK11.48497713
27MUSK1.47663522
28PRKD21.47441135
29BRSK21.47203724
30TEC1.42816896
31TRIM281.38155059
32CDK191.38077439
33IRAK21.36661714
34ADRBK21.35925946
35DAPK21.31874061
36PLK21.28871440
37MAP3K141.26318018
38TIE11.26233835
39EIF2AK21.25274262
40BMPR1B1.24587654
41PIM21.23068784
42PHKG11.18642610
43PHKG21.18642610
44BCKDK1.16279608
45FGFR21.15854475
46VRK21.15338608
47MAP3K41.14965069
48PTK2B1.12502739
49BMPR21.11145200
50EIF2AK31.09904637
51RIPK41.08553357
52INSRR1.03904432
53GRK71.02018892
54PNCK1.01659493
55PAK31.00963777
56NTRK20.96645277
57PLK30.92745543
58MAPKAPK30.90388053
59NEK60.87604954
60NTRK30.87284205
61EPHB20.86561850
62STK390.86117496
63VRK10.85836404
64ERBB30.84823873
65MARK10.84736190
66PBK0.83917182
67CDK30.83445272
68ZAK0.81975698
69PRKCG0.81513637
70IKBKB0.79596519
71IKBKE0.77330481
72CSNK1G10.76970438
73CSNK1G30.76920929
74BTK0.75679500
75MAP3K120.75326492
76CSNK1G20.75207324
77BRAF0.73081754
78GRK10.73033459
79CSK0.72817222
80MAPK150.71615116
81TSSK60.67390811
82LYN0.63140633
83PIK3CG0.62475872
84ITK0.62333216
85EIF2AK10.60832463
86PINK10.60540896
87WNK40.60056741
88CAMK10.58125547
89PLK40.57881286
90BCR0.57490834
91TRPM70.56576076
92PRKCQ0.56395998
93AKT30.53556530
94TNK20.53518421
95PKN10.51752061
96MAPK110.51646622
97MAPK120.51518888
98HIPK20.49669438
99STK380.49313483
100CAMKK20.48735145
101CSNK1A1L0.48564330
102DYRK20.48247888
103PRKG20.47188835
104PASK0.45585364
105NUAK10.45152181
106MAPKAPK50.45067244
107CDK80.44926631
108FER0.44602794
109KIT0.43855319
110STK38L0.43076303
111STK110.42301594
112SIK20.40771394
113MST40.39912110
114CSNK1A10.39295173
115FLT30.39266391
116ADRBK10.39257870
117TAF10.39161043
118CAMK2B0.38519871
119PRKCE0.37309445
120SYK0.36375921
121MAPK40.36185713
122PRKCZ0.35545194
123WNK10.35232547
124GRK50.34964557
125CSF1R0.34759134
126OBSCN0.34649860
127CHUK0.34275299
128CAMK2A0.33424597
129MINK10.33104614
130RPS6KA50.33086923
131LCK0.32964174
132PRKCA0.32670270
133PIM10.32010919
134FGR0.31790532
135PIK3CA0.31576852
136NEK90.31544482
137PRKAA10.31437796
138CSNK1D0.30975667
139TYRO30.30534718
140UHMK10.29788501
141PRKACA0.29190133
142IGF1R0.29014389
143CDK90.28649722
144PRKCI0.28521006
145MAP2K60.27065319
146PRKG10.25289420
147CDK70.25047703
148HCK0.25040288
149OXSR10.24133585
150TBK10.24127795
151DYRK30.24077217
152CSNK2A10.22679312
153PRKCD0.21846742
154NME10.20607211
155DYRK1A0.20147375

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.71730016
2Fanconi anemia pathway_Homo sapiens_hsa034602.70957434
3Homologous recombination_Homo sapiens_hsa034402.57797014
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.43668432
5Butanoate metabolism_Homo sapiens_hsa006502.40215421
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.37455857
7Nitrogen metabolism_Homo sapiens_hsa009102.32658498
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.23347521
9Protein export_Homo sapiens_hsa030602.04710489
10Graft-versus-host disease_Homo sapiens_hsa053322.04270982
11Selenocompound metabolism_Homo sapiens_hsa004502.01039685
12Arachidonic acid metabolism_Homo sapiens_hsa005902.00549546
13Other glycan degradation_Homo sapiens_hsa005111.97846769
14Oxidative phosphorylation_Homo sapiens_hsa001901.96491114
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.90470656
16Phototransduction_Homo sapiens_hsa047441.88882833
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.84464279
18Intestinal immune network for IgA production_Homo sapiens_hsa046721.75939877
19Allograft rejection_Homo sapiens_hsa053301.75516492
20Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.70735748
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.70703244
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69102600
23Basal transcription factors_Homo sapiens_hsa030221.62765343
24Tryptophan metabolism_Homo sapiens_hsa003801.62476291
25Autoimmune thyroid disease_Homo sapiens_hsa053201.62092941
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.55774850
27One carbon pool by folate_Homo sapiens_hsa006701.53731477
28Proteasome_Homo sapiens_hsa030501.52060464
29Sphingolipid metabolism_Homo sapiens_hsa006001.48351903
30RNA polymerase_Homo sapiens_hsa030201.44033597
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.41841445
32Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.41172805
33Propanoate metabolism_Homo sapiens_hsa006401.40745907
34Asthma_Homo sapiens_hsa053101.39137757
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.32374662
36Ether lipid metabolism_Homo sapiens_hsa005651.28792880
37Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.28556494
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27616614
39Hematopoietic cell lineage_Homo sapiens_hsa046401.26220076
40Parkinsons disease_Homo sapiens_hsa050121.26094667
41Primary immunodeficiency_Homo sapiens_hsa053401.22996305
42Huntingtons disease_Homo sapiens_hsa050161.22977085
43Peroxisome_Homo sapiens_hsa041461.22414786
44Collecting duct acid secretion_Homo sapiens_hsa049661.18676993
45Measles_Homo sapiens_hsa051621.15411969
46Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.14977575
47RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14826442
48Taste transduction_Homo sapiens_hsa047421.14756196
49Malaria_Homo sapiens_hsa051441.14330080
50Caffeine metabolism_Homo sapiens_hsa002321.13918020
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.13609583
52Olfactory transduction_Homo sapiens_hsa047401.13562004
53DNA replication_Homo sapiens_hsa030301.11475594
54Nicotine addiction_Homo sapiens_hsa050331.11470302
55Alzheimers disease_Homo sapiens_hsa050101.10934814
56Purine metabolism_Homo sapiens_hsa002301.10144892
57Linoleic acid metabolism_Homo sapiens_hsa005911.09838601
58RNA degradation_Homo sapiens_hsa030181.09090025
59Rheumatoid arthritis_Homo sapiens_hsa053231.08541401
60Pyrimidine metabolism_Homo sapiens_hsa002401.02832476
61Chemical carcinogenesis_Homo sapiens_hsa052041.00182284
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.98201396
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.94629846
64Sulfur metabolism_Homo sapiens_hsa009200.92859177
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.90737499
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.90455865
67Morphine addiction_Homo sapiens_hsa050320.90001344
68Insulin secretion_Homo sapiens_hsa049110.89380287
69Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88910238
70Fat digestion and absorption_Homo sapiens_hsa049750.87763049
71Sulfur relay system_Homo sapiens_hsa041220.87262142
72Primary bile acid biosynthesis_Homo sapiens_hsa001200.86243366
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85984060
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.85292545
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84171521
76Type I diabetes mellitus_Homo sapiens_hsa049400.80342035
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79744196
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.79307873
79Salivary secretion_Homo sapiens_hsa049700.76943583
80Spliceosome_Homo sapiens_hsa030400.75759143
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75465216
82Retinol metabolism_Homo sapiens_hsa008300.75297789
83Circadian rhythm_Homo sapiens_hsa047100.74229602
84Basal cell carcinoma_Homo sapiens_hsa052170.72701713
85Nucleotide excision repair_Homo sapiens_hsa034200.71309789
86Glycerolipid metabolism_Homo sapiens_hsa005610.71197502
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.71182936
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71059537
89Pertussis_Homo sapiens_hsa051330.70824937
90Circadian entrainment_Homo sapiens_hsa047130.70722051
91Serotonergic synapse_Homo sapiens_hsa047260.69931925
92African trypanosomiasis_Homo sapiens_hsa051430.69923491
93Leishmaniasis_Homo sapiens_hsa051400.68563982
94Wnt signaling pathway_Homo sapiens_hsa043100.68456617
95Non-homologous end-joining_Homo sapiens_hsa034500.68259540
96Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.67914567
97beta-Alanine metabolism_Homo sapiens_hsa004100.67875379
98Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.67722518
99ABC transporters_Homo sapiens_hsa020100.66996846
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.66829365
101Herpes simplex infection_Homo sapiens_hsa051680.65744107
102Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.64021049
103Pentose and glucuronate interconversions_Homo sapiens_hsa000400.61743486
104Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61415556
105GABAergic synapse_Homo sapiens_hsa047270.61360754
106Antigen processing and presentation_Homo sapiens_hsa046120.60016221
107Fatty acid elongation_Homo sapiens_hsa000620.58444554
108Mineral absorption_Homo sapiens_hsa049780.56658450
109p53 signaling pathway_Homo sapiens_hsa041150.56108238
110Base excision repair_Homo sapiens_hsa034100.53246483
111Mismatch repair_Homo sapiens_hsa034300.51947134
112Fatty acid degradation_Homo sapiens_hsa000710.51637315
113Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.50752852
114Glutamatergic synapse_Homo sapiens_hsa047240.48742266
115Cocaine addiction_Homo sapiens_hsa050300.47769668
116Staphylococcus aureus infection_Homo sapiens_hsa051500.46874690
117Thyroid cancer_Homo sapiens_hsa052160.46752878
118Cardiac muscle contraction_Homo sapiens_hsa042600.45340930
119Vitamin digestion and absorption_Homo sapiens_hsa049770.44623293
120Melanoma_Homo sapiens_hsa052180.44350068
121Tuberculosis_Homo sapiens_hsa051520.43677670
122Salmonella infection_Homo sapiens_hsa051320.41009049
123Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40876662
124Histidine metabolism_Homo sapiens_hsa003400.40024076
125Phagosome_Homo sapiens_hsa041450.39480456
126Long-term depression_Homo sapiens_hsa047300.38916079
127Regulation of autophagy_Homo sapiens_hsa041400.38430979
128Influenza A_Homo sapiens_hsa051640.36271658
129Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.35947817
130Melanogenesis_Homo sapiens_hsa049160.35371973
131Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34514406
132Metabolic pathways_Homo sapiens_hsa011000.34431628
133Systemic lupus erythematosus_Homo sapiens_hsa053220.34323217
134Ovarian steroidogenesis_Homo sapiens_hsa049130.34022563
135Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33569518
136Calcium signaling pathway_Homo sapiens_hsa040200.33535068
137Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33513819
138N-Glycan biosynthesis_Homo sapiens_hsa005100.33408871
139Dopaminergic synapse_Homo sapiens_hsa047280.33129403
140Fatty acid metabolism_Homo sapiens_hsa012120.33015153
141Dorso-ventral axis formation_Homo sapiens_hsa043200.32531791

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