

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | detection of molecule of bacterial origin (GO:0032490) | 5.99207679 |
| 2 | microglial cell activation (GO:0001774) | 5.38549380 |
| 3 | modulation by symbiont of host immune response (GO:0052553) | 5.14365679 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.14365679 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 5.14365679 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.14365679 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.14365679 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.14365679 |
| 9 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.06217046 |
| 10 | macrophage activation involved in immune response (GO:0002281) | 4.96635086 |
| 11 | response to peptidoglycan (GO:0032494) | 4.61806487 |
| 12 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.56897303 |
| 13 | regulation of hypersensitivity (GO:0002883) | 4.39686777 |
| 14 | macrophage activation (GO:0042116) | 4.38899340 |
| 15 | cellular response to ethanol (GO:0071361) | 4.38864023 |
| 16 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.38707903 |
| 17 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.19531407 |
| 18 | dosage compensation (GO:0007549) | 4.18022594 |
| 19 | detection of external biotic stimulus (GO:0098581) | 4.17408560 |
| 20 | cellular extravasation (GO:0045123) | 3.96085526 |
| 21 | mature B cell differentiation involved in immune response (GO:0002313) | 3.95948180 |
| 22 | response to muramyl dipeptide (GO:0032495) | 3.93673033 |
| 23 | hepatocyte apoptotic process (GO:0097284) | 3.90439317 |
| 24 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.78890100 |
| 25 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.74708506 |
| 26 | response to host immune response (GO:0052572) | 3.74708506 |
| 27 | determination of adult lifespan (GO:0008340) | 3.69560254 |
| 28 | myeloid leukocyte mediated immunity (GO:0002444) | 3.67711382 |
| 29 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.67431739 |
| 30 | neutrophil mediated immunity (GO:0002446) | 3.67208005 |
| 31 | histone mRNA catabolic process (GO:0071044) | 3.64801175 |
| 32 | myeloid cell activation involved in immune response (GO:0002275) | 3.61049047 |
| 33 | detection of biotic stimulus (GO:0009595) | 3.60796709 |
| 34 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.57558063 |
| 35 | negative regulation of interleukin-12 production (GO:0032695) | 3.57400899 |
| 36 | detection of other organism (GO:0098543) | 3.53495457 |
| 37 | response to host (GO:0075136) | 3.50208492 |
| 38 | response to host defenses (GO:0052200) | 3.50208492 |
| 39 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.50208492 |
| 40 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.49660670 |
| 41 | T-helper cell differentiation (GO:0042093) | 3.49660670 |
| 42 | neutrophil activation involved in immune response (GO:0002283) | 3.46824883 |
| 43 | negative regulation of inclusion body assembly (GO:0090084) | 3.45596035 |
| 44 | nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) | 3.43394375 |
| 45 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.35760437 |
| 46 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.33442368 |
| 47 | positive regulation of B cell differentiation (GO:0045579) | 3.32988268 |
| 48 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.28753087 |
| 49 | mature B cell differentiation (GO:0002335) | 3.28032598 |
| 50 | establishment of protein localization to Golgi (GO:0072600) | 3.25603676 |
| 51 | protein targeting to Golgi (GO:0000042) | 3.25355335 |
| 52 | regulation of gamma-delta T cell activation (GO:0046643) | 3.23992201 |
| 53 | peptide catabolic process (GO:0043171) | 3.23036895 |
| 54 | positive regulation of granulocyte differentiation (GO:0030854) | 3.22895487 |
| 55 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.21148343 |
| 56 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.17517752 |
| 57 | regulation of mast cell degranulation (GO:0043304) | 3.13606085 |
| 58 | I-kappaB phosphorylation (GO:0007252) | 3.12714619 |
| 59 | B cell receptor signaling pathway (GO:0050853) | 3.10321187 |
| 60 | negative regulation of DNA repair (GO:0045738) | 3.08721727 |
| 61 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.05275300 |
| 62 | histone H3-K4 trimethylation (GO:0080182) | 3.04611419 |
| 63 | nuclear pore complex assembly (GO:0051292) | 3.02225857 |
| 64 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.99975664 |
| 65 | definitive hemopoiesis (GO:0060216) | 2.98793022 |
| 66 | iron ion import (GO:0097286) | 2.98330119 |
| 67 | positive regulation of microtubule polymerization (GO:0031116) | 2.98013584 |
| 68 | negative regulation of granulocyte differentiation (GO:0030853) | 2.94812674 |
| 69 | germ cell migration (GO:0008354) | 2.94393104 |
| 70 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.92623985 |
| 71 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872) | 2.91240652 |
| 72 | regulation of beta-amyloid formation (GO:1902003) | 2.90567761 |
| 73 | regulation of mast cell activation (GO:0033003) | 2.89248027 |
| 74 | embryonic process involved in female pregnancy (GO:0060136) | 2.89192730 |
| 75 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.88776095 |
| 76 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.88776095 |
| 77 | T cell differentiation involved in immune response (GO:0002292) | 2.88776095 |
| 78 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.85227061 |
| 79 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.85227061 |
| 80 | detection of bacterium (GO:0016045) | 2.82874730 |
| 81 | positive regulation of chemokine secretion (GO:0090197) | 2.81227006 |
| 82 | cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) | 2.80156055 |
| 83 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.78697835 |
| 84 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.78580298 |
| 85 | positive regulation of mast cell degranulation (GO:0043306) | 2.76431839 |
| 86 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.76431839 |
| 87 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.76416365 |
| 88 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.76047276 |
| 89 | regulation of macrophage cytokine production (GO:0010935) | 2.73561223 |
| 90 | regulation of granulocyte differentiation (GO:0030852) | 2.72849108 |
| 91 | leukocyte activation involved in immune response (GO:0002366) | 2.72005823 |
| 92 | cell activation involved in immune response (GO:0002263) | 2.72005823 |
| 93 | protein K11-linked deubiquitination (GO:0035871) | 2.70724567 |
| 94 | neural tube formation (GO:0001841) | 2.69717468 |
| 95 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.68046870 |
| 96 | regulation of leukocyte degranulation (GO:0043300) | 2.67471978 |
| 97 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2.67449549 |
| 98 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.67271206 |
| 99 | T cell activation involved in immune response (GO:0002286) | 2.65206193 |
| 100 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.64859684 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.09190527 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.91261767 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.74927278 |
| 4 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.34273535 |
| 5 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 3.08270866 |
| 6 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.96378983 |
| 7 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.78360184 |
| 8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.74280408 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.73483108 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.72584830 |
| 11 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.64515156 |
| 12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.63389024 |
| 13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.58972004 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.45093324 |
| 15 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.44361156 |
| 16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.34653790 |
| 17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.24999375 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.21004759 |
| 19 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.20739373 |
| 20 | MYB_26560356_Chip-Seq_TH2_Human | 2.13526207 |
| 21 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.13042342 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.09024580 |
| 23 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.01947317 |
| 24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.98387153 |
| 25 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.97506023 |
| 26 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.96204753 |
| 27 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.95206528 |
| 28 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.94019818 |
| 29 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.90463083 |
| 30 | MYB_26560356_Chip-Seq_TH1_Human | 1.85408082 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.79978397 |
| 32 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.76241506 |
| 33 | SPI1_23127762_ChIP-Seq_K562_Human | 1.71475755 |
| 34 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.69320385 |
| 35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.60630650 |
| 36 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.59485496 |
| 37 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.58111407 |
| 38 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.56910295 |
| 39 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.55393480 |
| 40 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.52029720 |
| 41 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.49049913 |
| 42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.48899375 |
| 43 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.47651954 |
| 44 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.47618371 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.46476952 |
| 46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.39409645 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37714367 |
| 48 | GATA1_22025678_ChIP-Seq_K562_Human | 1.37626995 |
| 49 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.35325988 |
| 50 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.33996714 |
| 51 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.33468691 |
| 52 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.33088949 |
| 53 | TP53_16413492_ChIP-PET_HCT116_Human | 1.32713706 |
| 54 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.32272533 |
| 55 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.29628401 |
| 56 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27978205 |
| 57 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.23766473 |
| 58 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21230455 |
| 59 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.20119344 |
| 60 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.19589878 |
| 61 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.18323578 |
| 62 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16702650 |
| 63 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.16459242 |
| 64 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.15940780 |
| 65 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.15648710 |
| 66 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.11383518 |
| 67 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07456906 |
| 68 | CJUN_26792858_Chip-Seq_BT549_Human | 1.05920324 |
| 69 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.05128910 |
| 70 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.03802537 |
| 71 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.02339847 |
| 72 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00226350 |
| 73 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00144706 |
| 74 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.00144706 |
| 75 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.99686388 |
| 76 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.99517696 |
| 77 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.99049119 |
| 78 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98579306 |
| 79 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.98101386 |
| 80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97123296 |
| 81 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96279542 |
| 82 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.95084616 |
| 83 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.93954414 |
| 84 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.93744200 |
| 85 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.92794565 |
| 86 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.90989651 |
| 87 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.90513440 |
| 88 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.89140396 |
| 89 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.88887286 |
| 90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.88875402 |
| 91 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.88167909 |
| 92 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.87858356 |
| 93 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.87084017 |
| 94 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.86911966 |
| 95 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.85500485 |
| 96 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.84235752 |
| 97 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.84235752 |
| 98 | GATA2_19941826_ChIP-Seq_K562_Human | 0.83141331 |
| 99 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.83012568 |
| 100 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.81946430 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002009_preneoplasia | 3.59895412 |
| 2 | MP0000569_abnormal_digit_pigmentation | 3.36982686 |
| 3 | MP0002166_altered_tumor_susceptibility | 3.21034023 |
| 4 | MP0002396_abnormal_hematopoietic_system | 3.08011575 |
| 5 | MP0003724_increased_susceptibility_to | 2.97208457 |
| 6 | MP0000465_gastrointestinal_hemorrhage | 2.81663256 |
| 7 | MP0008057_abnormal_DNA_replication | 2.78329168 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.76690884 |
| 9 | MP0008260_abnormal_autophagy | 2.56568912 |
| 10 | MP0003828_pulmonary_edema | 2.54225952 |
| 11 | MP0003656_abnormal_erythrocyte_physiolo | 2.42729575 |
| 12 | MP0002419_abnormal_innate_immunity | 2.22827599 |
| 13 | MP0003436_decreased_susceptibility_to | 2.18443913 |
| 14 | MP0002006_tumorigenesis | 2.08603006 |
| 15 | MP0005464_abnormal_platelet_physiology | 1.95224753 |
| 16 | MP0003950_abnormal_plasma_membrane | 1.93944604 |
| 17 | MP0003763_abnormal_thymus_physiology | 1.89269157 |
| 18 | MP0003300_gastrointestinal_ulcer | 1.88588611 |
| 19 | MP0008438_abnormal_cutaneous_collagen | 1.85481622 |
| 20 | MP0000685_abnormal_immune_system | 1.73531411 |
| 21 | MP0008007_abnormal_cellular_replicative | 1.73252744 |
| 22 | MP0005410_abnormal_fertilization | 1.72360564 |
| 23 | MP0001800_abnormal_humoral_immune | 1.69759157 |
| 24 | MP0010307_abnormal_tumor_latency | 1.68184745 |
| 25 | MP0002723_abnormal_immune_serum | 1.65411111 |
| 26 | MP0005025_abnormal_response_to | 1.64513276 |
| 27 | MP0003191_abnormal_cellular_cholesterol | 1.62467303 |
| 28 | MP0002452_abnormal_antigen_presenting | 1.60657396 |
| 29 | MP0004883_abnormal_blood_vessel | 1.59768306 |
| 30 | MP0004808_abnormal_hematopoietic_stem | 1.59504575 |
| 31 | MP0003172_abnormal_lysosome_physiology | 1.59262762 |
| 32 | MP0005397_hematopoietic_system_phenotyp | 1.57755672 |
| 33 | MP0001545_abnormal_hematopoietic_system | 1.57755672 |
| 34 | MP0005310_abnormal_salivary_gland | 1.52377501 |
| 35 | MP0001819_abnormal_immune_cell | 1.47131986 |
| 36 | MP0002420_abnormal_adaptive_immunity | 1.46163674 |
| 37 | MP0002405_respiratory_system_inflammati | 1.45697689 |
| 38 | MP0001879_abnormal_lymphatic_vessel | 1.44634910 |
| 39 | MP0005000_abnormal_immune_tolerance | 1.43636210 |
| 40 | MP0005671_abnormal_response_to | 1.42969550 |
| 41 | MP0003303_peritoneal_inflammation | 1.42257586 |
| 42 | MP0000015_abnormal_ear_pigmentation | 1.39574678 |
| 43 | MP0002998_abnormal_bone_remodeling | 1.38926091 |
| 44 | MP0002398_abnormal_bone_marrow | 1.37853924 |
| 45 | MP0003221_abnormal_cardiomyocyte_apopto | 1.32364953 |
| 46 | MP0002722_abnormal_immune_system | 1.30609139 |
| 47 | MP0005076_abnormal_cell_differentiation | 1.30469972 |
| 48 | MP0001986_abnormal_taste_sensitivity | 1.29543075 |
| 49 | MP0002332_abnormal_exercise_endurance | 1.29482459 |
| 50 | MP0009785_altered_susceptibility_to | 1.29235254 |
| 51 | MP0010368_abnormal_lymphatic_system | 1.29188520 |
| 52 | MP0009697_abnormal_copulation | 1.26628292 |
| 53 | MP0001851_eye_inflammation | 1.26566413 |
| 54 | MP0000604_amyloidosis | 1.25453201 |
| 55 | MP0005164_abnormal_response_to | 1.23496765 |
| 56 | MP0000716_abnormal_immune_system | 1.20552575 |
| 57 | MP0001915_intracranial_hemorrhage | 1.18892117 |
| 58 | MP0000689_abnormal_spleen_morphology | 1.18601069 |
| 59 | MP0004947_skin_inflammation | 1.18337979 |
| 60 | MP0003279_aneurysm | 1.17477137 |
| 61 | MP0000371_diluted_coat_color | 1.16309675 |
| 62 | MP0009764_decreased_sensitivity_to | 1.15890377 |
| 63 | MP0003186_abnormal_redox_activity | 1.15571266 |
| 64 | MP0003091_abnormal_cell_migration | 1.14110570 |
| 65 | MP0005409_darkened_coat_color | 1.12932728 |
| 66 | MP0001533_abnormal_skeleton_physiology | 1.12488881 |
| 67 | MP0000749_muscle_degeneration | 1.11262125 |
| 68 | MP0006082_CNS_inflammation | 1.09084044 |
| 69 | MP0000703_abnormal_thymus_morphology | 1.07287626 |
| 70 | MP0001845_abnormal_inflammatory_respons | 1.06323477 |
| 71 | MP0000249_abnormal_blood_vessel | 1.05431450 |
| 72 | MP0002429_abnormal_blood_cell | 1.04718430 |
| 73 | MP0005387_immune_system_phenotype | 1.01601032 |
| 74 | MP0001790_abnormal_immune_system | 1.01601032 |
| 75 | MP0009115_abnormal_fat_cell | 0.98880221 |
| 76 | MP0005174_abnormal_tail_pigmentation | 0.91726388 |
| 77 | MP0002933_joint_inflammation | 0.90161332 |
| 78 | MP0005275_abnormal_skin_tensile | 0.89438316 |
| 79 | MP0003690_abnormal_glial_cell | 0.85884014 |
| 80 | MP0001853_heart_inflammation | 0.85129371 |
| 81 | MP0004381_abnormal_hair_follicle | 0.83830612 |
| 82 | MP0009763_increased_sensitivity_to | 0.83121377 |
| 83 | MP0002971_abnormal_brown_adipose | 0.81539807 |
| 84 | MP0002019_abnormal_tumor_incidence | 0.81040591 |
| 85 | MP0005647_abnormal_sex_gland | 0.79571908 |
| 86 | MP0004484_altered_response_of | 0.78994761 |
| 87 | MP0005376_homeostasis/metabolism_phenot | 0.78434973 |
| 88 | MP0003011_delayed_dark_adaptation | 0.78369459 |
| 89 | MP0010352_gastrointestinal_tract_polyps | 0.76774151 |
| 90 | MP0000733_abnormal_muscle_development | 0.76271736 |
| 91 | MP0003329_amyloid_beta_deposits | 0.73505637 |
| 92 | MP0003077_abnormal_cell_cycle | 0.73497720 |
| 93 | MP0008469_abnormal_protein_level | 0.72518815 |
| 94 | MP0001984_abnormal_olfaction | 0.71120383 |
| 95 | MP0003866_abnormal_defecation | 0.70954449 |
| 96 | MP0003075_altered_response_to | 0.70866429 |
| 97 | MP0008873_increased_physiological_sensi | 0.69693442 |
| 98 | MP0005621_abnormal_cell_physiology | 0.69266969 |
| 99 | MP0000858_altered_metastatic_potential | 0.68875801 |
| 100 | MP0006054_spinal_hemorrhage | 0.67202390 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Conjunctival telangiectasia (HP:0000524) | 4.60347964 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 4.41334562 |
| 3 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 4.23499256 |
| 4 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 4.17251621 |
| 5 | Spondylolisthesis (HP:0003302) | 3.95518113 |
| 6 | Recurrent abscess formation (HP:0002722) | 3.87543510 |
| 7 | Colitis (HP:0002583) | 3.67728416 |
| 8 | Spinal cord lesions (HP:0100561) | 3.63828701 |
| 9 | Syringomyelia (HP:0003396) | 3.63828701 |
| 10 | Mediastinal lymphadenopathy (HP:0100721) | 3.41073063 |
| 11 | Recurrent fungal infections (HP:0002841) | 3.38813844 |
| 12 | Glomerulonephritis (HP:0000099) | 3.38766466 |
| 13 | Papillary thyroid carcinoma (HP:0002895) | 3.36908266 |
| 14 | Eczematoid dermatitis (HP:0000976) | 3.36784290 |
| 15 | Recurrent cutaneous fungal infections (HP:0011370) | 3.30486331 |
| 16 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.30486331 |
| 17 | Retrobulbar optic neuritis (HP:0100654) | 3.21562896 |
| 18 | Optic neuritis (HP:0100653) | 3.21562896 |
| 19 | IgM deficiency (HP:0002850) | 3.20308026 |
| 20 | Recurrent skin infections (HP:0001581) | 3.09433681 |
| 21 | Gastrointestinal infarctions (HP:0005244) | 3.08704181 |
| 22 | T lymphocytopenia (HP:0005403) | 2.97843598 |
| 23 | Gingivitis (HP:0000230) | 2.96908396 |
| 24 | Arterial tortuosity (HP:0005116) | 2.91814761 |
| 25 | Upper motor neuron abnormality (HP:0002127) | 2.90270374 |
| 26 | Abnormality of T cell number (HP:0011839) | 2.88102661 |
| 27 | Acute myeloid leukemia (HP:0004808) | 2.84052441 |
| 28 | Eosinophilia (HP:0001880) | 2.76931149 |
| 29 | Spinal muscular atrophy (HP:0007269) | 2.76831432 |
| 30 | Arterial thrombosis (HP:0004420) | 2.75890251 |
| 31 | Resting tremor (HP:0002322) | 2.70640958 |
| 32 | Orchitis (HP:0100796) | 2.69875195 |
| 33 | Osteomyelitis (HP:0002754) | 2.67092762 |
| 34 | Hypoplasia of the thymus (HP:0000778) | 2.64581426 |
| 35 | Complement deficiency (HP:0004431) | 2.63699566 |
| 36 | Spontaneous hematomas (HP:0007420) | 2.59712658 |
| 37 | Myositis (HP:0100614) | 2.56912284 |
| 38 | Recurrent viral infections (HP:0004429) | 2.55359784 |
| 39 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.52788348 |
| 40 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.52261329 |
| 41 | Granulocytopenia (HP:0001913) | 2.51566087 |
| 42 | Inflammation of the large intestine (HP:0002037) | 2.49171869 |
| 43 | Hemoptysis (HP:0002105) | 2.45433493 |
| 44 | Postural instability (HP:0002172) | 2.41553399 |
| 45 | Mucosal telangiectasiae (HP:0100579) | 2.40591176 |
| 46 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.36222507 |
| 47 | Abnormal platelet function (HP:0011869) | 2.32325812 |
| 48 | Impaired platelet aggregation (HP:0003540) | 2.32325812 |
| 49 | Systemic lupus erythematosus (HP:0002725) | 2.32145981 |
| 50 | Chronic diarrhea (HP:0002028) | 2.31412429 |
| 51 | Vascular tortuosity (HP:0004948) | 2.28246586 |
| 52 | Gastrointestinal inflammation (HP:0004386) | 2.27800540 |
| 53 | Subacute progressive viral hepatitis (HP:0006572) | 2.26613357 |
| 54 | Periodontitis (HP:0000704) | 2.26059770 |
| 55 | Absent frontal sinuses (HP:0002688) | 2.25754275 |
| 56 | Abnormality of the frontal sinuses (HP:0002687) | 2.25742755 |
| 57 | Fatigue (HP:0012378) | 2.24139271 |
| 58 | Abnormality of the prostate (HP:0008775) | 2.24038347 |
| 59 | Narrow palate (HP:0000189) | 2.23754391 |
| 60 | Tubulointerstitial nephritis (HP:0001970) | 2.22890611 |
| 61 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.22619034 |
| 62 | Epistaxis (HP:0000421) | 2.21823697 |
| 63 | Abnormality of eosinophils (HP:0001879) | 2.20280994 |
| 64 | Cerebral aneurysm (HP:0004944) | 2.16687139 |
| 65 | Prostate neoplasm (HP:0100787) | 2.15180248 |
| 66 | Delayed closure of the anterior fontanelle (HP:0001476) | 2.14710965 |
| 67 | Cheilitis (HP:0100825) | 2.14604248 |
| 68 | Difficulty running (HP:0009046) | 2.14192793 |
| 69 | Keratoconjunctivitis sicca (HP:0001097) | 2.13340022 |
| 70 | Thickened helices (HP:0000391) | 2.11371559 |
| 71 | Leukocytosis (HP:0001974) | 2.09419703 |
| 72 | Glucose intolerance (HP:0000833) | 2.09393539 |
| 73 | Viral hepatitis (HP:0006562) | 2.09206970 |
| 74 | Metaphyseal dysplasia (HP:0100255) | 2.08893597 |
| 75 | Thyroiditis (HP:0100646) | 2.08793786 |
| 76 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.05306810 |
| 77 | Short middle phalanx of the 5th finger (HP:0004220) | 2.05092787 |
| 78 | Gingival bleeding (HP:0000225) | 2.04798665 |
| 79 | Anorexia (HP:0002039) | 2.04417787 |
| 80 | Autoimmune hemolytic anemia (HP:0001890) | 2.01693763 |
| 81 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.00568463 |
| 82 | Amyotrophic lateral sclerosis (HP:0007354) | 1.98186860 |
| 83 | Abnormality of T cells (HP:0002843) | 1.96513478 |
| 84 | Peritonitis (HP:0002586) | 1.92850579 |
| 85 | Chest pain (HP:0100749) | 1.92731313 |
| 86 | Keratoconjunctivitis (HP:0001096) | 1.91272518 |
| 87 | Glomerulopathy (HP:0100820) | 1.87936117 |
| 88 | Myocardial infarction (HP:0001658) | 1.84014983 |
| 89 | Thyroid carcinoma (HP:0002890) | 1.83772122 |
| 90 | IgA deficiency (HP:0002720) | 1.83659609 |
| 91 | Meningitis (HP:0001287) | 1.83085731 |
| 92 | Abnormality of the peritoneum (HP:0002585) | 1.82385834 |
| 93 | Abnormality of complement system (HP:0005339) | 1.78940169 |
| 94 | Cellulitis (HP:0100658) | 1.78364097 |
| 95 | Scanning speech (HP:0002168) | 1.76688658 |
| 96 | Nephritis (HP:0000123) | 1.73794282 |
| 97 | Pulmonary embolism (HP:0002204) | 1.73444971 |
| 98 | Amyloidosis (HP:0011034) | 1.72821070 |
| 99 | Abnormal glucose tolerance (HP:0001952) | 1.72466620 |
| 100 | Broad ribs (HP:0000885) | 1.69506270 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TGFBR2 | 3.72000887 |
| 2 | FES | 3.16284268 |
| 3 | BLK | 2.75000654 |
| 4 | PIK3CG | 2.65714375 |
| 5 | AKT3 | 2.48049673 |
| 6 | EIF2AK3 | 2.35964828 |
| 7 | MAP3K14 | 2.27557496 |
| 8 | ZAK | 2.21077473 |
| 9 | TXK | 2.20916043 |
| 10 | CDK8 | 2.14910264 |
| 11 | IKBKE | 2.13181131 |
| 12 | BMPR2 | 1.93761412 |
| 13 | CSF1R | 1.89325428 |
| 14 | CDK6 | 1.78243973 |
| 15 | KIT | 1.74574828 |
| 16 | FRK | 1.68201305 |
| 17 | JAK1 | 1.64749675 |
| 18 | TEC | 1.63925067 |
| 19 | MAP3K13 | 1.59595445 |
| 20 | JAK3 | 1.54573701 |
| 21 | MOS | 1.51745282 |
| 22 | PIM1 | 1.51599435 |
| 23 | RIPK4 | 1.50707814 |
| 24 | TIE1 | 1.42566761 |
| 25 | TNK2 | 1.42041747 |
| 26 | BTK | 1.39609444 |
| 27 | GRK6 | 1.38966752 |
| 28 | FLT3 | 1.38119281 |
| 29 | SRPK1 | 1.37578024 |
| 30 | STK4 | 1.28623294 |
| 31 | NEK9 | 1.26118247 |
| 32 | RAF1 | 1.25631755 |
| 33 | MAP3K3 | 1.24932720 |
| 34 | SCYL2 | 1.24489309 |
| 35 | TYK2 | 1.22442792 |
| 36 | EIF2AK2 | 1.20379723 |
| 37 | SYK | 1.18575595 |
| 38 | MAP2K3 | 1.15658729 |
| 39 | MAP3K2 | 1.11943718 |
| 40 | EIF2AK1 | 1.09768183 |
| 41 | CSK | 1.08712149 |
| 42 | BRD4 | 1.04987804 |
| 43 | CAMK1G | 1.04906668 |
| 44 | IRAK1 | 1.02628593 |
| 45 | IKBKB | 1.02478930 |
| 46 | LYN | 1.01281784 |
| 47 | MAP4K1 | 1.00199670 |
| 48 | FGR | 0.98410941 |
| 49 | FGFR3 | 0.97468571 |
| 50 | MAPK7 | 0.97277654 |
| 51 | TBK1 | 0.97086487 |
| 52 | NEK6 | 0.96989239 |
| 53 | CDK3 | 0.96973274 |
| 54 | GRK7 | 0.96872270 |
| 55 | TRPM7 | 0.96043343 |
| 56 | HCK | 0.94017247 |
| 57 | JAK2 | 0.90504980 |
| 58 | PKN1 | 0.86704887 |
| 59 | PDK1 | 0.86571347 |
| 60 | PDK2 | 0.86141215 |
| 61 | LCK | 0.86060941 |
| 62 | YES1 | 0.84053701 |
| 63 | TLK1 | 0.83923090 |
| 64 | NUAK1 | 0.80163725 |
| 65 | STK10 | 0.78953080 |
| 66 | IRAK4 | 0.77734649 |
| 67 | EGFR | 0.77440656 |
| 68 | CAMK1D | 0.74266118 |
| 69 | RPS6KA5 | 0.73418960 |
| 70 | MAP3K7 | 0.70813468 |
| 71 | DYRK1B | 0.68796667 |
| 72 | STK38 | 0.67528751 |
| 73 | MAPK11 | 0.66511521 |
| 74 | SGK2 | 0.64619387 |
| 75 | CCNB1 | 0.64396650 |
| 76 | ZAP70 | 0.62333416 |
| 77 | SGK3 | 0.62298179 |
| 78 | BMPR1B | 0.56565178 |
| 79 | CDK9 | 0.56054999 |
| 80 | ITK | 0.54221557 |
| 81 | TAOK3 | 0.53832656 |
| 82 | MARK3 | 0.50086943 |
| 83 | DMPK | 0.47999748 |
| 84 | PLK2 | 0.47960715 |
| 85 | MAP3K12 | 0.47608341 |
| 86 | EPHA3 | 0.45566241 |
| 87 | MAP3K6 | 0.45440382 |
| 88 | RPS6KB2 | 0.45288365 |
| 89 | TESK2 | 0.45227455 |
| 90 | ABL1 | 0.44089180 |
| 91 | CAMK4 | 0.42338942 |
| 92 | PRKAA2 | 0.41598291 |
| 93 | STK16 | 0.41581877 |
| 94 | MAPK4 | 0.41046349 |
| 95 | RET | 0.40908269 |
| 96 | LATS1 | 0.39753635 |
| 97 | IRAK2 | 0.37271716 |
| 98 | MTOR | 0.35324739 |
| 99 | WNK1 | 0.35049766 |
| 100 | PDPK1 | 0.34703797 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.01481254 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.68732819 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.50961177 |
| 4 | Legionellosis_Homo sapiens_hsa05134 | 2.47364676 |
| 5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.42418008 |
| 6 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.14451480 |
| 7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.08470721 |
| 8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.04105368 |
| 9 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.91727794 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.85896724 |
| 11 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.73805749 |
| 12 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.68331707 |
| 13 | Measles_Homo sapiens_hsa05162 | 1.68224311 |
| 14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.62657587 |
| 15 | Tuberculosis_Homo sapiens_hsa05152 | 1.60878409 |
| 16 | Other glycan degradation_Homo sapiens_hsa00511 | 1.58294113 |
| 17 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.53003760 |
| 18 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.47522578 |
| 19 | Influenza A_Homo sapiens_hsa05164 | 1.46270406 |
| 20 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.44887267 |
| 21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.44596257 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.42141417 |
| 23 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.41861099 |
| 24 | Hepatitis B_Homo sapiens_hsa05161 | 1.41366799 |
| 25 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.40173408 |
| 26 | Pertussis_Homo sapiens_hsa05133 | 1.39894064 |
| 27 | Alcoholism_Homo sapiens_hsa05034 | 1.37802563 |
| 28 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.36746626 |
| 29 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.36509571 |
| 30 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.36207031 |
| 31 | Platelet activation_Homo sapiens_hsa04611 | 1.35435402 |
| 32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.33648384 |
| 33 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.30498058 |
| 34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.29142950 |
| 35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.25326328 |
| 36 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.23664034 |
| 37 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.22841884 |
| 38 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.20194878 |
| 39 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.13249915 |
| 40 | Phagosome_Homo sapiens_hsa04145 | 1.11312969 |
| 41 | Malaria_Homo sapiens_hsa05144 | 1.09083662 |
| 42 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.04397210 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03121046 |
| 44 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.03035405 |
| 45 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.00273128 |
| 46 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.98714709 |
| 47 | Apoptosis_Homo sapiens_hsa04210 | 0.97054540 |
| 48 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.86316799 |
| 49 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.85298005 |
| 50 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.85294598 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.84855345 |
| 52 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.84470333 |
| 53 | Asthma_Homo sapiens_hsa05310 | 0.84273085 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.83989694 |
| 55 | Circadian rhythm_Homo sapiens_hsa04710 | 0.82173336 |
| 56 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.82136928 |
| 57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.81540316 |
| 58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.79047674 |
| 59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.78651555 |
| 60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76354514 |
| 61 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.74514016 |
| 62 | DNA replication_Homo sapiens_hsa03030 | 0.74508013 |
| 63 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.73635958 |
| 64 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.73026814 |
| 65 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.72400470 |
| 66 | Glioma_Homo sapiens_hsa05214 | 0.71402140 |
| 67 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67868802 |
| 68 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.65946607 |
| 69 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.64985905 |
| 70 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.64799507 |
| 71 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.64362888 |
| 72 | Allograft rejection_Homo sapiens_hsa05330 | 0.63774401 |
| 73 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.63134298 |
| 74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.61707093 |
| 75 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61587297 |
| 76 | Prostate cancer_Homo sapiens_hsa05215 | 0.61517416 |
| 77 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.60620420 |
| 78 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.60550756 |
| 79 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59031046 |
| 80 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.58486882 |
| 81 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.54686555 |
| 82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54137384 |
| 83 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.54131895 |
| 84 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.53985101 |
| 85 | Prion diseases_Homo sapiens_hsa05020 | 0.52957139 |
| 86 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.52247854 |
| 87 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51543759 |
| 88 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.50392092 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.49965603 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48743459 |
| 91 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.46481980 |
| 92 | Amoebiasis_Homo sapiens_hsa05146 | 0.46244290 |
| 93 | Lysine degradation_Homo sapiens_hsa00310 | 0.46238177 |
| 94 | HTLV-I infection_Homo sapiens_hsa05166 | 0.44733935 |
| 95 | Mismatch repair_Homo sapiens_hsa03430 | 0.44151272 |
| 96 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43954858 |
| 97 | Hepatitis C_Homo sapiens_hsa05160 | 0.41421324 |
| 98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.41308657 |
| 99 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.40934414 |
| 100 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.40479203 |

