TSNAXIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome reaction (GO:0007340)9.99709150
2binding of sperm to zona pellucida (GO:0007339)9.65495540
3cell wall macromolecule metabolic process (GO:0044036)9.60547155
4cell wall macromolecule catabolic process (GO:0016998)9.60547155
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.46132674
6cell-cell recognition (GO:0009988)9.42301966
7plasma membrane fusion (GO:0045026)9.37277735
8piRNA metabolic process (GO:0034587)9.01137082
9spermatid development (GO:0007286)8.91300287
10regulation of cilium movement (GO:0003352)8.84469805
11reproduction (GO:0000003)8.48760376
12male meiosis (GO:0007140)8.18710154
13synaptonemal complex organization (GO:0070193)7.60912266
14synaptonemal complex assembly (GO:0007130)7.24032841
15single fertilization (GO:0007338)7.17889251
16ventricular system development (GO:0021591)6.94901505
17sperm capacitation (GO:0048240)6.76411183
18negative regulation of inclusion body assembly (GO:0090084)6.43712389
19fertilization (GO:0009566)6.14430904
20* spermatogenesis (GO:0007283)5.82941611
21* male gamete generation (GO:0048232)5.80722425
22microtubule severing (GO:0051013)5.68538450
23DNA methylation involved in gamete generation (GO:0043046)5.58365185
24male meiosis I (GO:0007141)5.54393753
25axoneme assembly (GO:0035082)5.47127877
26* gamete generation (GO:0007276)5.33824015
27regulation of inclusion body assembly (GO:0090083)5.21237208
28regulation of microtubule-based movement (GO:0060632)5.17574452
29germ cell development (GO:0007281)5.03915220
30organic cation transport (GO:0015695)5.02780431
31chromosome organization involved in meiosis (GO:0070192)5.00943418
32cellular process involved in reproduction in multicellular organism (GO:0022412)4.98457117
33primary alcohol catabolic process (GO:0034310)4.96186448
34microtubule depolymerization (GO:0007019)4.93087080
35protein localization to cilium (GO:0061512)4.89492002
36intraciliary transport (GO:0042073)4.83581882
37meiotic nuclear division (GO:0007126)4.73955248
38cell recognition (GO:0008037)4.57005604
39meiosis I (GO:0007127)4.55289923
40calcium ion-dependent exocytosis (GO:0017156)4.50317182
41seminiferous tubule development (GO:0072520)4.43470073
42vitamin transmembrane transport (GO:0035461)4.43073576
43left/right pattern formation (GO:0060972)4.32387002
44GTP biosynthetic process (GO:0006183)4.23095498
45nucleoside diphosphate phosphorylation (GO:0006165)4.23012437
46* multicellular organismal reproductive process (GO:0048609)4.19937634
47protein polyglutamylation (GO:0018095)4.18367273
48meiotic cell cycle (GO:0051321)4.16327688
49cell projection assembly (GO:0030031)4.14940434
50ethanol metabolic process (GO:0006067)4.13679668
51diterpenoid biosynthetic process (GO:0016102)4.10414627
52microtubule polymerization or depolymerization (GO:0031109)4.02733944
53cilium organization (GO:0044782)4.02244279
54microtubule-based movement (GO:0007018)3.97133522
55spermatid nucleus differentiation (GO:0007289)3.93139834
56left/right axis specification (GO:0070986)3.88918354
57cilium assembly (GO:0042384)3.81595836
58cilium morphogenesis (GO:0060271)3.80589281
59UTP biosynthetic process (GO:0006228)3.78279921
60lung epithelium development (GO:0060428)3.76893049
61one-carbon compound transport (GO:0019755)3.71828849
62negative regulation of T cell differentiation in thymus (GO:0033085)3.68819895
63genitalia morphogenesis (GO:0035112)3.68348519
64cellular component assembly involved in morphogenesis (GO:0010927)3.57689963
65monoubiquitinated protein deubiquitination (GO:0035520)3.56492816
66smoothened signaling pathway (GO:0007224)3.54583445
67establishment of tissue polarity (GO:0007164)3.52185173
68establishment of planar polarity (GO:0001736)3.52185173
69glomerular epithelial cell development (GO:0072310)3.52147476
70nonmotile primary cilium assembly (GO:0035058)3.48449511
71establishment of monopolar cell polarity (GO:0061162)3.46961820
72establishment or maintenance of monopolar cell polarity (GO:0061339)3.46961820
73chaperone-mediated protein complex assembly (GO:0051131)3.44156740
74UTP metabolic process (GO:0046051)3.43475443
75glycerol ether metabolic process (GO:0006662)3.41017502
76gene silencing by RNA (GO:0031047)3.39167206
77establishment of apical/basal cell polarity (GO:0035089)3.38261286
78determination of left/right symmetry (GO:0007368)3.38204624
79* multicellular organismal development (GO:0007275)3.31735761
80determination of bilateral symmetry (GO:0009855)3.22142531
81chromosome condensation (GO:0030261)3.21441564
82negative regulation of organelle assembly (GO:1902116)3.18658774
83ethanol oxidation (GO:0006069)3.15730158
84microtubule bundle formation (GO:0001578)3.15544569
85lateral sprouting from an epithelium (GO:0060601)3.14844136
86protein refolding (GO:0042026)3.14811063
87ether metabolic process (GO:0018904)3.14456112
88specification of symmetry (GO:0009799)3.14215686
89cytoplasmic microtubule organization (GO:0031122)3.12684386
90DNA packaging (GO:0006323)3.12556867
91centriole assembly (GO:0098534)3.06407018
92regulation of protein polyubiquitination (GO:1902914)3.03048515
93guanosine-containing compound biosynthetic process (GO:1901070)3.01911214
94terpenoid biosynthetic process (GO:0016114)3.01179519
95regulation of interleukin-5 production (GO:0032674)3.00183789
96meiotic cell cycle process (GO:1903046)2.99451927
97response to xenobiotic stimulus (GO:0009410)2.96314543
98negative regulation of B cell mediated immunity (GO:0002713)2.96143576
99negative regulation of immunoglobulin mediated immune response (GO:0002890)2.96143576
100pyrimidine-containing compound transmembrane transport (GO:0072531)2.96077879
101regulation of spindle checkpoint (GO:0090231)2.95752413
102synapsis (GO:0007129)2.94867239
103lateral ventricle development (GO:0021670)2.94456304
104positive regulation of smoothened signaling pathway (GO:0045880)2.94105329
105lactate metabolic process (GO:0006089)2.92859061
106retinal rod cell development (GO:0046548)2.92833619
107centriole replication (GO:0007099)2.92204890
108regulation of centriole replication (GO:0046599)2.91838598
109regulation of interleukin-13 production (GO:0032656)2.89433500
110tolerance induction (GO:0002507)2.88781582
111retinoic acid metabolic process (GO:0042573)2.88616829
112regulation of collateral sprouting (GO:0048670)2.87086521
113microtubule-based process (GO:0007017)2.82668236
114alditol metabolic process (GO:0019400)2.79849873
115amino-acid betaine transport (GO:0015838)2.79556102
116carnitine transport (GO:0015879)2.79556102
117embryonic camera-type eye development (GO:0031076)2.76223528
118CTP metabolic process (GO:0046036)2.75088485
119CTP biosynthetic process (GO:0006241)2.75088485
120carnitine transmembrane transport (GO:1902603)2.74797073
121organelle assembly (GO:0070925)2.73814963
122regulation of meiosis I (GO:0060631)2.73581530
123limb development (GO:0060173)2.73413469
124appendage development (GO:0048736)2.73413469
125cerebral cortex neuron differentiation (GO:0021895)2.72728580
126apical protein localization (GO:0045176)2.72038387
127single strand break repair (GO:0000012)2.71973422
128heart looping (GO:0001947)2.67425640
129glycolytic process (GO:0006096)2.67242203
130photoreceptor cell maintenance (GO:0045494)2.65773690
131protein K11-linked deubiquitination (GO:0035871)2.65261593
132polyol catabolic process (GO:0046174)2.62620388
133peptidyl-glutamic acid modification (GO:0018200)2.59338654
134regulation of smoothened signaling pathway (GO:0008589)2.56592448
135nucleus organization (GO:0006997)2.54371864
136mitotic sister chromatid cohesion (GO:0007064)2.53587864
137embryonic heart tube morphogenesis (GO:0003143)2.51346005
138asymmetric protein localization (GO:0008105)2.46321796
139central nervous system myelination (GO:0022010)2.45763654
140axon ensheathment in central nervous system (GO:0032291)2.45763654
141camera-type eye morphogenesis (GO:0048593)2.45682498
142carnitine metabolic process (GO:0009437)2.42747805
143brain morphogenesis (GO:0048854)2.42081029
144negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.38579257
145retinol metabolic process (GO:0042572)2.37524471
146phosphatidylethanolamine biosynthetic process (GO:0006646)2.36366345
147ear development (GO:0043583)2.35850436
148embryonic body morphogenesis (GO:0010172)2.29595568
149CDP-diacylglycerol biosynthetic process (GO:0016024)2.29503361
150negative regulation of humoral immune response (GO:0002921)2.28637526
151regulation of cilium assembly (GO:1902017)2.26988934
152regulation of autophagic vacuole assembly (GO:2000785)2.25729212
153primary alcohol metabolic process (GO:0034308)2.24815531
154exogenous drug catabolic process (GO:0042738)2.23089710
155phosphatidylcholine biosynthetic process (GO:0006656)2.20837796
156cilium or flagellum-dependent cell motility (GO:0001539)15.5179213
157axonemal dynein complex assembly (GO:0070286)13.1374142
158fusion of sperm to egg plasma membrane (GO:0007342)12.3126373
159sperm motility (GO:0030317)12.1666726
160epithelial cilium movement (GO:0003351)11.1440819
161cilium movement (GO:0003341)11.1116138
162acrosome assembly (GO:0001675)10.8295901
163sperm-egg recognition (GO:0035036)10.5272750
164motile cilium assembly (GO:0044458)10.4354128
165multicellular organism reproduction (GO:0032504)10.3203019

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.04905912
2EZH2_22144423_ChIP-Seq_EOC_Human4.91880599
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.80893003
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.25549355
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.88848686
6DROSHA_22980978_ChIP-Seq_HELA_Human2.87685531
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.58452682
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.31504147
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.23116040
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.21477789
11EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.09735450
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.0678785
13PCGF2_27294783_Chip-Seq_ESCs_Mouse1.99766936
14EZH2_27294783_Chip-Seq_ESCs_Mouse1.98984612
15CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.97305375
16CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.91358734
17ZNF274_21170338_ChIP-Seq_K562_Hela1.87726583
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85761831
19ELK4_26923725_Chip-Seq_MESODERM_Mouse1.82291524
20VDR_22108803_ChIP-Seq_LS180_Human1.79711395
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.78228230
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.73884550
23WDR5_24793694_ChIP-Seq_LNCAP_Human1.69588208
24KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.67177648
25SMC4_20622854_ChIP-Seq_HELA_Human1.66539691
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.66517681
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64517415
28TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.64309116
29KAP1_22055183_ChIP-Seq_ESCs_Mouse1.62307933
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.54605105
31FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.54556959
32SOX2_22085726_ChIP-Seq_NPCs_Mouse1.54225339
33CTCF_27219007_Chip-Seq_Bcells_Human1.54076843
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.52946210
35STAT1_17558387_ChIP-Seq_HELA_Human1.52826074
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52813388
37TAL1_26923725_Chip-Seq_HPCs_Mouse1.51856107
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.51585285
39NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48673842
40JARID2_20075857_ChIP-Seq_MESCs_Mouse1.48057040
41SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.47630379
42MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.46729488
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.46665661
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.44567634
45GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.43216283
46IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40080837
47CBP_20019798_ChIP-Seq_JUKART_Human1.40080837
48FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39027141
49SUZ12_27294783_Chip-Seq_NPCs_Mouse1.38557508
50EED_16625203_ChIP-ChIP_MESCs_Mouse1.38214819
51AHR_22903824_ChIP-Seq_MCF-7_Human1.38034831
52* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.36326818
53GATA3_21867929_ChIP-Seq_CD8_Mouse1.35227000
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.33919913
55BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33348159
56ARNT_22903824_ChIP-Seq_MCF-7_Human1.32905655
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32767764
58MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32757796
59P68_20966046_ChIP-Seq_HELA_Human1.31148843
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.30106636
61ERG_21242973_ChIP-ChIP_JURKAT_Human1.27981057
62TP63_22573176_ChIP-Seq_HFKS_Human1.27860155
63PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.27421646
64IGF1R_20145208_ChIP-Seq_DFB_Human1.26487753
65RNF2_27304074_Chip-Seq_NSC_Mouse1.26106705
66P53_21459846_ChIP-Seq_SAOS-2_Human1.25999059
67RNF2_27304074_Chip-Seq_ESCs_Mouse1.25360379
68KDM2B_26808549_Chip-Seq_REH_Human1.25091364
69FLI1_21867929_ChIP-Seq_TH2_Mouse1.25044936
70ELF1_20517297_ChIP-Seq_JURKAT_Human1.24693759
71LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.23359507
72ERA_21632823_ChIP-Seq_H3396_Human1.23037185
73GF1_26923725_Chip-Seq_HPCs_Mouse1.22528838
74TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.21563608
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20535708
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19562173
77TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19562173
78REST_21632747_ChIP-Seq_MESCs_Mouse1.19452654
79EZH2_27304074_Chip-Seq_ESCs_Mouse1.18656969
80CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17229799
81SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.17152691
82MTF2_20144788_ChIP-Seq_MESCs_Mouse1.17074912
83RUNX1_27514584_Chip-Seq_MCF-7_Human1.16212284
84ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.16211103
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.14882517
86SMAD4_21799915_ChIP-Seq_A2780_Human1.14015557
87CTCF_20526341_ChIP-Seq_ESCs_Human1.13709008
88CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13203761
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.12891155
90SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.12703841
91SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.11937130
92CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11918023
93CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11688303
94OCT4_18555785_Chip-Seq_ESCs_Mouse1.11379379
95RNF2_18974828_ChIP-Seq_MESCs_Mouse1.11184937
96EZH2_18974828_ChIP-Seq_MESCs_Mouse1.11184937
97PHF8_20622854_ChIP-Seq_HELA_Human1.11056407
98TDRD3_21172665_ChIP-Seq_MCF-7_Human1.10899663
99SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.10797429
100SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.10633132
101ZFP57_27257070_Chip-Seq_ESCs_Mouse1.10582408
102NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10521882
103CRX_20693478_ChIP-Seq_RETINA_Mouse1.10411413
104EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10208099
105GATA3_21867929_ChIP-Seq_TH1_Mouse1.09312812
106SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.09068708
107SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.08987613
108ERG_20517297_ChIP-Seq_VCAP_Human1.08805235
109P53_22387025_ChIP-Seq_ESCs_Mouse1.07554640
110MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07463807
111CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06491168
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06410314
113EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06169714
114STAT1_20625510_ChIP-Seq_HELA_Human1.05381944
115ETV1_20927104_ChIP-Seq_GIST48_Human1.05201411
116DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05189626
117PHF8_20622853_ChIP-Seq_HELA_Human1.04048292
118RAD21_21589869_ChIP-Seq_MESCs_Mouse1.03696666
119EZH2_27294783_Chip-Seq_NPCs_Mouse1.03467851
120RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.03173755
121JARID2_20064375_ChIP-Seq_MESCs_Mouse1.02761888
122RUNX1_26923725_Chip-Seq_HPCs_Mouse1.02169624
123OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01906101
124P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01418046
125FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01266929
126TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00341482
127P300_18555785_Chip-Seq_ESCs_Mouse1.00216908
128RUNX2_22187159_ChIP-Seq_PCA_Human0.99725504
129GBX2_23144817_ChIP-Seq_PC3_Human0.99679063
130CMYC_18555785_Chip-Seq_ESCs_Mouse0.98819859
131SPI1_26923725_Chip-Seq_HPCs_Mouse0.98510448
132TP53_18474530_ChIP-ChIP_U2OS_Human0.98252025
133ESRRB_18555785_Chip-Seq_ESCs_Mouse0.97985009
134KLF4_18555785_Chip-Seq_ESCs_Mouse0.96837458
135KLF5_25053715_ChIP-Seq_YYC3_Human0.96192677
136STAT3_18555785_Chip-Seq_ESCs_Mouse0.95970422
137YY1_22570637_ChIP-Seq_MALME-3M_Human0.95528669
138EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95351231
139* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94422640
140HNFA_21074721_ChIP-Seq_CACO-2_Human0.94186567
141CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.94154625
142EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94029083
143SOX2_21211035_ChIP-Seq_LN229_Human0.94027996
144SMAD3_21741376_ChIP-Seq_EPCs_Human0.93886935
145MYC_19829295_ChIP-Seq_ESCs_Human0.93881478
146SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.93797312
147RING1B_27294783_Chip-Seq_ESCs_Mouse0.93540536
148* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.92630162
149PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.92496238
150SMAD4_21741376_ChIP-Seq_EPCs_Human0.92366813
151E2F1_20622854_ChIP-Seq_HELA_Human0.92184124
152FOXM1_26456572_ChIP-Seq_MCF-7_Human0.91987571
153AR_21572438_ChIP-Seq_LNCaP_Human0.91368344
154AR_19668381_ChIP-Seq_PC3_Human0.91036210
155SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90983646
156PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.90638423
157TBL1_22424771_ChIP-Seq_293T_Human0.90258647
158NFYB_21822215_ChIP-Seq_K562_Human0.90171907
159TP63_23658742_ChIP-Seq_EP156T_Human0.90160217
160EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.89911690
161GF1B_26923725_Chip-Seq_HPCs_Mouse0.89721807
162ESET_19884257_ChIP-Seq_ESCs_Mouse0.89569835
163FOXA1_25329375_ChIP-Seq_VCAP_Human0.88959677
164FOXA1_27270436_Chip-Seq_PROSTATE_Human0.88959677
165SOX9_26525672_Chip-Seq_HEART_Mouse0.88632485
166ER_23166858_ChIP-Seq_MCF-7_Human0.88306373
167PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87518087
168MYC_27129775_Chip-Seq_CORNEA_Mouse0.87195101
169CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86906656
170PU1_27457419_Chip-Seq_LIVER_Mouse0.86813551
171LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.86129318
172E2F1_18555785_Chip-Seq_ESCs_Mouse0.86013687
173TCF4_23295773_ChIP-Seq_U87_Human0.85862378

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.94136982
2MP0001929_abnormal_gametogenesis5.42836108
3MP0008877_abnormal_DNA_methylation4.62993054
4MP0002653_abnormal_ependyma_morphology3.96195084
5MP0008875_abnormal_xenobiotic_pharmacok3.77908489
6MP0002210_abnormal_sex_determination3.74182009
7MP0002161_abnormal_fertility/fecundity3.22306702
8MP0001145_abnormal_male_reproductive3.12678298
9MP0008789_abnormal_olfactory_epithelium3.02571732
10MP0010030_abnormal_orbit_morphology2.99607401
11MP0000566_synostosis2.95376224
12MP0000653_abnormal_sex_gland2.74829112
13MP0005623_abnormal_meninges_morphology2.51530948
14MP0002160_abnormal_reproductive_system2.48162369
15MP0002249_abnormal_larynx_morphology2.36810813
16MP0005499_abnormal_olfactory_system2.31309591
17MP0005394_taste/olfaction_phenotype2.31309591
18MP0004043_abnormal_pH_regulation2.25904759
19MP0005670_abnormal_white_adipose2.12091839
20MP0001984_abnormal_olfaction2.08677561
21MP0009780_abnormal_chondrocyte_physiolo2.05556869
22MP0002638_abnormal_pupillary_reflex2.04527468
23MP0004885_abnormal_endolymph2.02104430
24MP0005410_abnormal_fertilization14.8818149
25MP0005083_abnormal_biliary_tract1.94235093
26MP0001485_abnormal_pinna_reflex1.90535514
27MP0005248_abnormal_Harderian_gland1.84761738
28MP0002277_abnormal_respiratory_mucosa1.77229866
29MP0008057_abnormal_DNA_replication1.74290648
30MP0005647_abnormal_sex_gland1.73978496
31MP0002735_abnormal_chemical_nociception1.63955088
32MP0008058_abnormal_DNA_repair1.57967414
33MP0002734_abnormal_mechanical_nocicepti1.57219438
34MP0009379_abnormal_foot_pigmentation1.55134784
35MP0000778_abnormal_nervous_system1.53696881
36MP0004859_abnormal_synaptic_plasticity1.49825244
37MP0000026_abnormal_inner_ear1.49084424
38MP0002282_abnormal_trachea_morphology1.46843389
39MP0000049_abnormal_middle_ear1.40215941
40MP0002822_catalepsy1.37908064
41MP0005389_reproductive_system_phenotype1.32936976
42MP0003646_muscle_fatigue1.31944348
43MP0005423_abnormal_somatic_nervous1.28662722
44MP0000955_abnormal_spinal_cord1.27796346
45MP0008995_early_reproductive_senescence1.27509292
46MP0009046_muscle_twitch1.24989591
47MP0002233_abnormal_nose_morphology1.24514934
48MP0001346_abnormal_lacrimal_gland1.23360211
49MP0000631_abnormal_neuroendocrine_gland1.19996635
50MP0002928_abnormal_bile_duct1.19666466
51MP0000678_abnormal_parathyroid_gland1.15033515
52MP0003938_abnormal_ear_development1.12774311
53MP0000383_abnormal_hair_follicle1.12027827
54MP0003878_abnormal_ear_physiology1.11671264
55MP0005377_hearing/vestibular/ear_phenot1.11671264
56MP0001970_abnormal_pain_threshold1.10147786
57MP0001963_abnormal_hearing_physiology1.09179470
58MP0001486_abnormal_startle_reflex1.07966490
59MP0001502_abnormal_circadian_rhythm1.07200992
60MP0004133_heterotaxia1.06736168
61MP0008004_abnormal_stomach_pH1.05742033
62MP0001529_abnormal_vocalization1.05024790
63MP0002168_other_aberrant_phenotype1.02893885
64MP0002909_abnormal_adrenal_gland1.01094106
65MP0001765_abnormal_ion_homeostasis1.00783750
66MP0002572_abnormal_emotion/affect_behav0.99872363
67MP0003011_delayed_dark_adaptation0.97322752
68MP0009745_abnormal_behavioral_response0.96140062
69MP0003937_abnormal_limbs/digits/tail_de0.95798064
70MP0003136_yellow_coat_color0.93921888
71MP0010094_abnormal_chromosome_stability0.93452801
72MP0001299_abnormal_eye_distance/0.91539650
73MP0003122_maternal_imprinting0.90845206
74MP0003950_abnormal_plasma_membrane0.89136653
75MP0002116_abnormal_craniofacial_bone0.88108829
76MP0006276_abnormal_autonomic_nervous0.87313752
77MP0002557_abnormal_social/conspecific_i0.85251825
78MP0005395_other_phenotype0.84832173
79MP0003880_abnormal_central_pattern0.84351191
80MP0002272_abnormal_nervous_system0.83945902
81MP0000534_abnormal_ureter_morphology0.83239256
82MP0003786_premature_aging0.82996228
83MP0002882_abnormal_neuron_morphology0.82622186
84MP0002736_abnormal_nociception_after0.82356502
85MP0001968_abnormal_touch/_nociception0.81681628
86MP0003635_abnormal_synaptic_transmissio0.80321108
87MP0002063_abnormal_learning/memory/cond0.80020627
88MP0004233_abnormal_muscle_weight0.79297669
89MP0005409_darkened_coat_color0.78993753
90MP0009384_cardiac_valve_regurgitation0.78062167
91MP0009053_abnormal_anal_canal0.76804272
92MP0002064_seizures0.75506528
93MP0006292_abnormal_olfactory_placode0.75345906
94MP0008007_abnormal_cellular_replicative0.72736017
95MP0005171_absent_coat_pigmentation0.70041268
96MP0001849_ear_inflammation0.68977378
97MP0005551_abnormal_eye_electrophysiolog0.68931541
98MP0002067_abnormal_sensory_capabilities0.67217962
99MP0001879_abnormal_lymphatic_vessel0.66742990
100MP0000358_abnormal_cell_content/0.62572637
101MP0002733_abnormal_thermal_nociception0.62535037
102MP0002234_abnormal_pharynx_morphology0.60322064
103MP0001545_abnormal_hematopoietic_system0.55052138
104MP0005397_hematopoietic_system_phenotyp0.55052138
105MP0003699_abnormal_female_reproductive0.54732456
106MP0004134_abnormal_chest_morphology0.53886193
107MP0005253_abnormal_eye_physiology0.51976616
108MP0001293_anophthalmia0.51974838
109MP0002102_abnormal_ear_morphology0.50373169
110MP0001119_abnormal_female_reproductive0.49534915
111MP0003115_abnormal_respiratory_system0.48587947
112MP0005636_abnormal_mineral_homeostasis0.48556962
113MP0005391_vision/eye_phenotype0.46438700
114MP0001324_abnormal_eye_pigmentation0.45717930
115MP0003943_abnormal_hepatobiliary_system0.44776601
116MP0001851_eye_inflammation0.38376058
117MP0009115_abnormal_fat_cell0.38029808
118MP0005666_abnormal_adipose_tissue0.37298194
119MP0002132_abnormal_respiratory_system0.35690904
120MP0003861_abnormal_nervous_system0.35377189
121MP0004808_abnormal_hematopoietic_stem0.34598207
122MP0002405_respiratory_system_inflammati0.34522966
123MP0003111_abnormal_nucleus_morphology0.33536294
124MP0003942_abnormal_urinary_system0.33336741
125MP0004036_abnormal_muscle_relaxation0.33213890
126MP0001727_abnormal_embryo_implantation0.32853593
127MP0002152_abnormal_brain_morphology0.32245268
128MP0003329_amyloid_beta_deposits0.31458320
129MP0002092_abnormal_eye_morphology0.30273477
130MP0001873_stomach_inflammation0.29150811
131MP0003633_abnormal_nervous_system0.28996456
132MP0004019_abnormal_vitamin_homeostasis0.28479588
133MP0006072_abnormal_retinal_apoptosis0.27939546
134MP0009278_abnormal_bone_marrow0.27679432
135MP0010307_abnormal_tumor_latency0.26585412
136MP0004811_abnormal_neuron_physiology0.26230845
137MP0005195_abnormal_posterior_eye0.26214465
138MP0000569_abnormal_digit_pigmentation0.24789174
139MP0003045_fibrosis0.24343145
140MP0002133_abnormal_respiratory_system0.23781697
141MP0005388_respiratory_system_phenotype0.23781697
142MP0002269_muscular_atrophy0.23296642
143MP0002084_abnormal_developmental_patter0.22552279
144MP0001730_embryonic_growth_arrest0.21977700
145MP0000313_abnormal_cell_death0.21408376
146MP0002229_neurodegeneration0.21234834
147MP0001764_abnormal_homeostasis0.20891640
148MP0003634_abnormal_glial_cell0.20564471
149MP0001919_abnormal_reproductive_system0.20083767
150MP0003631_nervous_system_phenotype0.19873403
151MP0002109_abnormal_limb_morphology0.18744029
152MP0002295_abnormal_pulmonary_circulatio0.17942775
153MP0002752_abnormal_somatic_nervous0.17798408
154MP0005646_abnormal_pituitary_gland0.17438796
155MP0002169_no_abnormal_phenotype0.16807919
156MP0003936_abnormal_reproductive_system0.16669037
157MP0002873_normal_phenotype0.16469031
158MP0003948_abnormal_gas_homeostasis0.15772841
159MP0002108_abnormal_muscle_morphology0.14953808
160MP0004742_abnormal_vestibular_system0.14163604
161MP0000427_abnormal_hair_cycle0.14135740
162MP0003879_abnormal_hair_cell0.14042473
163MP0010368_abnormal_lymphatic_system0.13956493
164MP0004145_abnormal_muscle_electrophysio0.13823065
165MP0000001_mammalian_phenotype0.13720178

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.31906424
2Abnormal respiratory epithelium morphology (HP:0012253)9.31906424
3Abnormal ciliary motility (HP:0012262)9.14824050
4Rhinitis (HP:0012384)8.74200909
5Chronic bronchitis (HP:0004469)7.46089608
6Nasal polyposis (HP:0100582)6.39643153
7Infertility (HP:0000789)6.14775284
8Abnormality of the nasal mucosa (HP:0000433)5.24882684
9Bronchiectasis (HP:0002110)5.13373939
10Male infertility (HP:0003251)4.55839310
11Bronchitis (HP:0012387)4.45789690
12Nephronophthisis (HP:0000090)4.01391060
13Recurrent sinusitis (HP:0011108)3.52575982
14Recurrent otitis media (HP:0000403)3.28462340
15Atelectasis (HP:0100750)3.16306099
16Tubulointerstitial nephritis (HP:0001970)3.10066153
17Abnormality of the renal medulla (HP:0100957)3.03209947
18Medial flaring of the eyebrow (HP:0010747)2.81645435
19Molar tooth sign on MRI (HP:0002419)2.77264451
20Abnormality of midbrain morphology (HP:0002418)2.77264451
21Abnormality of the lower motor neuron (HP:0002366)2.68971461
22Supernumerary spleens (HP:0009799)2.53839802
23Pancreatic fibrosis (HP:0100732)2.52187910
24Recurrent bronchitis (HP:0002837)2.45589744
25Postaxial foot polydactyly (HP:0001830)2.45214734
26Abnormal spermatogenesis (HP:0008669)2.42207958
27Chronic otitis media (HP:0000389)2.33614858
28True hermaphroditism (HP:0010459)2.32615614
29Tubulointerstitial abnormality (HP:0001969)2.31505916
30Bile duct proliferation (HP:0001408)2.29695770
31Abnormal biliary tract physiology (HP:0012439)2.29695770
32Fibular hypoplasia (HP:0003038)2.27793608
33Abnormality of dentin (HP:0010299)2.21119654
34Congenital hepatic fibrosis (HP:0002612)2.20642400
35Tubular atrophy (HP:0000092)2.18432015
36Sclerocornea (HP:0000647)2.16605616
37Chronic sinusitis (HP:0011109)2.15280941
38Amyotrophic lateral sclerosis (HP:0007354)2.10471090
39Gonadotropin excess (HP:0000837)2.05694002
40Cystic liver disease (HP:0006706)2.05373542
41Hyperactive renin-angiotensin system (HP:0000841)2.02878533
42Occipital encephalocele (HP:0002085)2.02650645
43Abnormality of permanent molar morphology (HP:0011071)2.02324927
44Abnormality of the dental root (HP:0006486)2.02324927
45Taurodontia (HP:0000679)2.02324927
46Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.9075693
47Absent/shortened dynein arms (HP:0200106)11.8377124
48Dynein arm defect of respiratory motile cilia (HP:0012255)11.8377124
49Abnormal respiratory motile cilium physiology (HP:0012261)10.7310353
50Congenital primary aphakia (HP:0007707)1.92465982
51Aplasia/Hypoplasia of the tongue (HP:0010295)1.92395746
52Gait imbalance (HP:0002141)1.91986927
53Oculomotor apraxia (HP:0000657)1.91239475
54Abnormality of molar (HP:0011077)1.90925810
55Abnormality of molar morphology (HP:0011070)1.90925810
56Median cleft lip (HP:0000161)1.89981324
57Stage 5 chronic kidney disease (HP:0003774)1.85530689
58Aplasia/Hypoplasia of the spleen (HP:0010451)1.84491637
59Asplenia (HP:0001746)1.84239267
60Abnormality of the dental pulp (HP:0006479)1.83886027
61Impulsivity (HP:0100710)1.79332995
62Facial cleft (HP:0002006)1.78219779
63Azoospermia (HP:0000027)1.77633560
64Postaxial hand polydactyly (HP:0001162)1.73211143
65Broad distal phalanx of finger (HP:0009836)1.72696631
66Nephrogenic diabetes insipidus (HP:0009806)1.68594759
67Short ribs (HP:0000773)1.67927448
68Pancreatic cysts (HP:0001737)1.67896824
69Tubulointerstitial fibrosis (HP:0005576)1.62371752
70Hypoplasia of the capital femoral epiphysis (HP:0003090)1.59798474
71Impaired proprioception (HP:0010831)1.56001168
72Septo-optic dysplasia (HP:0100842)1.54790127
73Short nail (HP:0001799)1.53333378
74Furrowed tongue (HP:0000221)1.50832852
75Abnormal drinking behavior (HP:0030082)1.48788965
76Polydipsia (HP:0001959)1.48788965
77Abnormality of the renal cortex (HP:0011035)1.48054118
78Upper motor neuron abnormality (HP:0002127)1.47937356
79Male pseudohermaphroditism (HP:0000037)1.47219537
80Aplasia/Hypoplasia of the lens (HP:0008063)1.46679642
81Dyschromatopsia (HP:0007641)1.46211572
82Renal salt wasting (HP:0000127)1.46162076
83Genital tract atresia (HP:0001827)1.46144764
84Poor coordination (HP:0002370)1.45216671
85Renal dysplasia (HP:0000110)1.41621466
86Vaginal atresia (HP:0000148)1.39970795
87Anophthalmia (HP:0000528)1.39033840
88Hyperkalemia (HP:0002153)1.39006222
89Microglossia (HP:0000171)1.38879279
90Short thorax (HP:0010306)1.37717620
91Aplasia/Hypoplasia of the fibula (HP:0006492)1.37304730
92Nephropathy (HP:0000112)1.36443496
93Degeneration of the lateral corticospinal tracts (HP:0002314)1.36192283
94Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.36192283
95Absent frontal sinuses (HP:0002688)1.35238497
96Spastic tetraparesis (HP:0001285)1.33801353
97Bell-shaped thorax (HP:0001591)1.32459524
98J-shaped sella turcica (HP:0002680)1.32385440
99Chronic hepatic failure (HP:0100626)1.28175234
100Short femoral neck (HP:0100864)1.27175136
101Holoprosencephaly (HP:0001360)1.26750381
102Absent epiphyses (HP:0010577)1.26457806
103Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.26457806
104Decreased central vision (HP:0007663)1.26269398
105Narrow forehead (HP:0000341)1.25482023
106Decreased circulating renin level (HP:0003351)1.24903135
107Abnormality of renal excretion (HP:0011036)1.23762531
108Retinitis pigmentosa (HP:0000510)1.23575532
109Aganglionic megacolon (HP:0002251)1.23561125
11011 pairs of ribs (HP:0000878)1.22569524
111Heterotopia (HP:0002282)1.21850321
112Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.21800084
113Cone-rod dystrophy (HP:0000548)1.21403376
114Specific learning disability (HP:0001328)1.21147638
115Anencephaly (HP:0002323)1.20914534
116Maternal diabetes (HP:0009800)1.20840773
117Multicystic kidney dysplasia (HP:0000003)1.19974407
118Hyperaldosteronism (HP:0000859)1.18024530
119Broad foot (HP:0001769)1.17500330
120Preaxial hand polydactyly (HP:0001177)1.17479503
121Abnormal gallbladder physiology (HP:0012438)1.15713061
122Cholecystitis (HP:0001082)1.15713061
123Prominent nasal bridge (HP:0000426)1.13949093
124Abnormality of macular pigmentation (HP:0008002)1.11263466
125Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.10376137
126Abnormality of the middle phalanges of the toes (HP:0010183)1.08492827
127Intellectual disability, moderate (HP:0002342)1.08000379
128Abnormality of chloride homeostasis (HP:0011422)1.06344963

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.51981178
2PDK48.51981178
3PDK25.46484940
4TESK14.79751905
5PRKD33.80126794
6PNCK3.42451193
7ICK3.39688478
8MST43.31533200
9EPHA22.64317876
10MAPK152.62756692
11PTK2B2.61655419
12WNK42.35811456
13STK392.28829638
14NEK21.72128731
15BCR1.55650078
16EPHA41.52709675
17MAP3K41.49019907
18STK381.46096409
19PLK21.41208591
20NEK91.38810953
21EPHB21.35369589
22STK241.32351581
23WEE11.24418027
24NME11.19640512
25EEF2K1.17142930
26INSRR1.12404145
27EPHB11.12067037
28EPHA31.09764175
29DYRK1B1.06124287
30MAPK131.05256611
31WNK11.00380974
32MARK10.99910725
33TLK10.97187723
34WNK30.94552445
35ERBB20.89565084
36MAP4K20.89318826
37PDK10.87916461
38MAP3K20.87345396
39DYRK30.87230645
40DYRK20.85652541
41PASK0.84272180
42TYRO30.82658251
43STK30.82233682
44NTRK30.79539172
45STK38L0.79444511
46DYRK1A0.77316341
47LRRK20.76018761
48TSSK60.75160074
49CDK190.75041719
50CCNB10.72969743
51TTK0.69047838
52PRKCI0.68049277
53CAMK1G0.67681998
54CDC70.67504806
55TNIK0.66114727
56PINK10.64414051
57OXSR10.64198175
58MAP3K70.62546484
59BRSK20.59596897
60CAMKK20.56184047
61CHEK20.56016679
62SGK10.55646957
63IRAK10.55468199
64MAPKAPK50.55408376
65GRK10.55079167
66CASK0.54386240
67MET0.52824175
68SMG10.51857288
69MAP2K40.50258701
70MINK10.49469060
71SGK2230.47418539
72SGK4940.47418539
73PRKCG0.47167044
74CHEK10.46381666
75LMTK20.45603370
76ROCK10.45402038
77ATR0.44453717
78PIM20.43875408
79MAPKAPK30.43009652
80MUSK0.42919986
81UHMK10.42814420
82MAP3K110.42333168
83TESK20.40258690
84ADRBK20.38563422
85NTRK20.38216155
86DMPK0.38094162
87PRKCH0.35996570
88CAMK10.35400523
89PAK10.35382253
90CSNK1G20.35042140
91ERBB30.33534883
92ATM0.33240835
93CDK50.31997112
94PAK60.31418528
95PTK20.31351980
96PDPK10.31153164
97BMX0.30852297
98PRKCD0.30415074
99CAMKK10.30237055
100AKT20.28077363
101NTRK10.26970259
102RET0.26823435
103FGFR20.26811800
104BRSK10.26736818
105PLK40.26597908
106DDR20.26307786
107MAP2K60.26143719
108PLK10.25290845
109PAK20.25288256
110RIPK40.24799418
111NLK0.23809982
112PRKCE0.23808703
113RPS6KB10.21960182
114PBK0.21743476
115PRKAA10.20802653
116CDC42BPA0.20160686
117MTOR0.19991762
118NEK60.19646016
119CDK30.19262343
120AURKA0.16480083
121STK100.15512799
122BRAF0.14162624
123CDK120.13987863
124IRAK20.12151605
125RPS6KA10.09855364
126PRKCZ0.08608841
127CSNK2A10.08493567
128PRKCQ0.08462142
129PRKG20.07604823
130PRKDC0.07480636
131BMPR20.06883602
132PRKACG0.06811541
133CDK10.06704649
134MAPK80.06615834
135STK160.06501024
136GSK3B0.05165967
137RPS6KA20.04774018
138PRKG10.04434282
139CDK20.03611557
140CSNK2A20.03536752
141MARK20.03409865
142CDK150.02466015
143MAP2K70.02350754
144GSK3A0.01584112
145CSK0.01154791
146RPS6KA30.00864064
147PAK40.00508394
148CDK180.00433389
149CAMK2A0.00308725
150STK110.00139432
151CDK11A0.00022097
152EGFR-0.0212218
153PRKACA-0.0183780
154MAPK10-0.0140429
155CSF1R-0.0128301
156PRKCA-0.0120039
157BMPR1B-0.0115075
158MAPK1-0.0019404
159PRKCB-0.0016580
160CSNK1D-0.0015422

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.02007058
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.10324557
3Pyruvate metabolism_Homo sapiens_hsa006203.93220870
4Phenylalanine metabolism_Homo sapiens_hsa003603.61851311
5Fatty acid biosynthesis_Homo sapiens_hsa000613.40750453
6Histidine metabolism_Homo sapiens_hsa003403.25480927
7Propanoate metabolism_Homo sapiens_hsa006403.11889358
8Fanconi anemia pathway_Homo sapiens_hsa034602.80352644
9beta-Alanine metabolism_Homo sapiens_hsa004102.76908415
10Tyrosine metabolism_Homo sapiens_hsa003502.72697723
11Glucagon signaling pathway_Homo sapiens_hsa049222.69558628
12Basal transcription factors_Homo sapiens_hsa030222.65910191
13alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.49848328
14Linoleic acid metabolism_Homo sapiens_hsa005912.40536925
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.32565450
16Pentose phosphate pathway_Homo sapiens_hsa000302.29152522
17Huntingtons disease_Homo sapiens_hsa050162.28116696
18Dorso-ventral axis formation_Homo sapiens_hsa043202.25519338
19Selenocompound metabolism_Homo sapiens_hsa004502.06661661
20Glycerolipid metabolism_Homo sapiens_hsa005611.95835916
21Oocyte meiosis_Homo sapiens_hsa041141.92301441
22Carbohydrate digestion and absorption_Homo sapiens_hsa049731.73552829
23PPAR signaling pathway_Homo sapiens_hsa033201.69725757
24Nicotine addiction_Homo sapiens_hsa050331.69720369
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.69367374
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.68216094
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.67047058
28Amphetamine addiction_Homo sapiens_hsa050311.59620927
29Basal cell carcinoma_Homo sapiens_hsa052171.56427437
30Nitrogen metabolism_Homo sapiens_hsa009101.51110362
31Glycerophospholipid metabolism_Homo sapiens_hsa005641.43760112
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.39294031
33Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.37126148
34Purine metabolism_Homo sapiens_hsa002301.32456130
35Olfactory transduction_Homo sapiens_hsa047401.32000398
36Carbon metabolism_Homo sapiens_hsa012001.31346813
37Fructose and mannose metabolism_Homo sapiens_hsa000511.30043691
38Notch signaling pathway_Homo sapiens_hsa043301.29866653
39Glycosaminoglycan degradation_Homo sapiens_hsa005311.29123201
40Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.28475135
41Caffeine metabolism_Homo sapiens_hsa002321.28001636
42Renin secretion_Homo sapiens_hsa049241.24743456
43Mineral absorption_Homo sapiens_hsa049781.18134570
44Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.17794976
45Steroid biosynthesis_Homo sapiens_hsa001001.17153156
46Tight junction_Homo sapiens_hsa045301.16558153
47Axon guidance_Homo sapiens_hsa043601.10915412
48Antigen processing and presentation_Homo sapiens_hsa046121.09140670
49Ether lipid metabolism_Homo sapiens_hsa005651.08804105
50Steroid hormone biosynthesis_Homo sapiens_hsa001401.08601006
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.08544539
52mRNA surveillance pathway_Homo sapiens_hsa030151.08496039
53Cocaine addiction_Homo sapiens_hsa050301.07846432
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.05804516
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.05144567
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.04283448
57Cardiac muscle contraction_Homo sapiens_hsa042601.04198919
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.04047694
59Butanoate metabolism_Homo sapiens_hsa006501.02738323
60Fat digestion and absorption_Homo sapiens_hsa049751.02064967
61RNA transport_Homo sapiens_hsa030131.01490149
62Hippo signaling pathway_Homo sapiens_hsa043900.94660156
63Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90574998
64Biosynthesis of amino acids_Homo sapiens_hsa012300.88820858
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88355681
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.87554489
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83448174
68Peroxisome_Homo sapiens_hsa041460.82496556
69Collecting duct acid secretion_Homo sapiens_hsa049660.82379237
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81803751
71Glutathione metabolism_Homo sapiens_hsa004800.81338796
72Arginine and proline metabolism_Homo sapiens_hsa003300.80182096
73Type II diabetes mellitus_Homo sapiens_hsa049300.78500445
74Estrogen signaling pathway_Homo sapiens_hsa049150.77893351
75Choline metabolism in cancer_Homo sapiens_hsa052310.77242837
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76720963
77Glutamatergic synapse_Homo sapiens_hsa047240.73511773
78Fatty acid metabolism_Homo sapiens_hsa012120.73482796
79Sphingolipid metabolism_Homo sapiens_hsa006000.72896535
80Morphine addiction_Homo sapiens_hsa050320.72088502
81Circadian rhythm_Homo sapiens_hsa047100.70293944
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69512514
83ABC transporters_Homo sapiens_hsa020100.68923522
84Serotonergic synapse_Homo sapiens_hsa047260.68514698
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67559445
86Hedgehog signaling pathway_Homo sapiens_hsa043400.67251942
87Arachidonic acid metabolism_Homo sapiens_hsa005900.66849935
88Insulin secretion_Homo sapiens_hsa049110.65885471
89Long-term potentiation_Homo sapiens_hsa047200.65676933
90Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.64912993
91Calcium signaling pathway_Homo sapiens_hsa040200.64689431
92Fatty acid degradation_Homo sapiens_hsa000710.64187038
93Ovarian steroidogenesis_Homo sapiens_hsa049130.63729421
94Chemical carcinogenesis_Homo sapiens_hsa052040.63616685
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62398770
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62114583
97Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.60410830
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57923713
99Systemic lupus erythematosus_Homo sapiens_hsa053220.56693426
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55598840
101Pyrimidine metabolism_Homo sapiens_hsa002400.54782828
102Melanogenesis_Homo sapiens_hsa049160.52866947
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.49471832
104Taste transduction_Homo sapiens_hsa047420.49440129
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49335789
106Thyroid hormone synthesis_Homo sapiens_hsa049180.47005139
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.46354498
108Phototransduction_Homo sapiens_hsa047440.46274217
109Oxidative phosphorylation_Homo sapiens_hsa001900.45842589
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45730873
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44976944
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43778251
113GABAergic synapse_Homo sapiens_hsa047270.43382498
114Inositol phosphate metabolism_Homo sapiens_hsa005620.43161447
115Renin-angiotensin system_Homo sapiens_hsa046140.42159518
116Sulfur relay system_Homo sapiens_hsa041220.41611328
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.41090647
118Base excision repair_Homo sapiens_hsa034100.40871993
119Primary bile acid biosynthesis_Homo sapiens_hsa001200.40771303
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.40224076
121Circadian entrainment_Homo sapiens_hsa047130.40147492
122Metabolic pathways_Homo sapiens_hsa011000.39051338
123Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37799512
124Synaptic vesicle cycle_Homo sapiens_hsa047210.37374926
125cAMP signaling pathway_Homo sapiens_hsa040240.36524474
126Homologous recombination_Homo sapiens_hsa034400.35902584
127AMPK signaling pathway_Homo sapiens_hsa041520.35596418
128VEGF signaling pathway_Homo sapiens_hsa043700.34956955
129Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34265011
130Starch and sucrose metabolism_Homo sapiens_hsa005000.34106031
131Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34090148
132Cyanoamino acid metabolism_Homo sapiens_hsa004600.33978176
133Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33900460
134RNA degradation_Homo sapiens_hsa030180.33166686
135Tryptophan metabolism_Homo sapiens_hsa003800.33009263
136Legionellosis_Homo sapiens_hsa051340.32799227
137Endocytosis_Homo sapiens_hsa041440.32516471
138Vascular smooth muscle contraction_Homo sapiens_hsa042700.32482471
139Salivary secretion_Homo sapiens_hsa049700.31401980
140Gap junction_Homo sapiens_hsa045400.31123684
141Dopaminergic synapse_Homo sapiens_hsa047280.30284198
142Oxytocin signaling pathway_Homo sapiens_hsa049210.29617057
143B cell receptor signaling pathway_Homo sapiens_hsa046620.29316649
144Bile secretion_Homo sapiens_hsa049760.28229579
145Gastric acid secretion_Homo sapiens_hsa049710.28073865
146Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27189592
147Retinol metabolism_Homo sapiens_hsa008300.26759312
148Cell cycle_Homo sapiens_hsa041100.25296032
149Alcoholism_Homo sapiens_hsa050340.24015060
150Wnt signaling pathway_Homo sapiens_hsa043100.24001254
151Nucleotide excision repair_Homo sapiens_hsa034200.22762443
152Pancreatic secretion_Homo sapiens_hsa049720.22560110
153N-Glycan biosynthesis_Homo sapiens_hsa005100.21675415
154Protein digestion and absorption_Homo sapiens_hsa049740.20507125
155Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.15576950

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