TSPAN11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1surfactant homeostasis (GO:0043129)8.71790106
2neuron projection extension involved in neuron projection guidance (GO:1902284)7.72750695
3axon extension involved in axon guidance (GO:0048846)7.72750695
4pattern specification involved in kidney development (GO:0061004)6.91154500
5chemical homeostasis within a tissue (GO:0048875)6.89652674
6postsynaptic membrane organization (GO:0001941)5.29728888
7pyrimidine nucleobase catabolic process (GO:0006208)5.19702055
8positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003605.12181915
9endocardial cushion morphogenesis (GO:0003203)4.98193200
10presynaptic membrane assembly (GO:0097105)4.86552830
11protein heterotrimerization (GO:0070208)4.85616404
12epithelial cell differentiation involved in prostate gland development (GO:0060742)4.76030865
13presynaptic membrane organization (GO:0097090)4.70787803
14mesenchyme morphogenesis (GO:0072132)4.53393189
15axonal fasciculation (GO:0007413)4.50774485
16cell migration involved in heart development (GO:0060973)4.40489425
17negative regulation of chondrocyte differentiation (GO:0032331)4.22788698
18chondrocyte proliferation (GO:0035988)4.22474604
19negative regulation of axon guidance (GO:1902668)4.20581760
20negative regulation of axon extension involved in axon guidance (GO:0048843)4.17413802
21neuron recognition (GO:0008038)4.14153502
22mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)4.03336694
23nucleobase catabolic process (GO:0046113)3.99441707
24epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.98852299
25neuron cell-cell adhesion (GO:0007158)3.98323293
26lung epithelium development (GO:0060428)3.91435369
27axonemal dynein complex assembly (GO:0070286)3.80451467
28segment specification (GO:0007379)3.80390344
29skin morphogenesis (GO:0043589)3.75152907
30coronary vasculature morphogenesis (GO:0060977)3.74293568
31mesenchymal cell proliferation (GO:0010463)3.72409426
32central nervous system myelination (GO:0022010)3.70989885
33axon ensheathment in central nervous system (GO:0032291)3.70989885
34regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.67672258
35dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.65667609
36cell migration in hindbrain (GO:0021535)3.64180173
37lens fiber cell development (GO:0070307)3.63603874
38dendritic spine morphogenesis (GO:0060997)3.63242444
39positive regulation of epithelial to mesenchymal transition (GO:0010718)3.63109942
40bone trabecula formation (GO:0060346)3.62820628
41regulation of somitogenesis (GO:0014807)3.61570317
42negative regulation of oligodendrocyte differentiation (GO:0048715)3.60585599
43camera-type eye morphogenesis (GO:0048593)3.53063069
44regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.51230788
45Notch signaling involved in heart development (GO:0061314)3.49782689
46glomerular filtration (GO:0003094)3.48940547
47vocalization behavior (GO:0071625)3.48604333
48epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.47838047
49atrioventricular valve morphogenesis (GO:0003181)3.47265342
50regulation of axon guidance (GO:1902667)3.45643834
51renal filtration (GO:0097205)3.43922020
52cilium movement (GO:0003341)3.43800183
53positive regulation of gastrulation (GO:2000543)3.43657511
54glomerular basement membrane development (GO:0032836)3.43279499
55planar cell polarity pathway involved in neural tube closure (GO:0090179)3.41980366
56auditory behavior (GO:0031223)3.39416051
57heart valve formation (GO:0003188)3.34987501
58positive regulation of BMP signaling pathway (GO:0030513)3.34627583
59regulation of axon extension involved in axon guidance (GO:0048841)3.33751335
60epithelial cell fate commitment (GO:0072148)3.33638517
61collagen fibril organization (GO:0030199)3.32301798
62forebrain neuron differentiation (GO:0021879)3.32128366
63retinal ganglion cell axon guidance (GO:0031290)3.30752163
64collecting duct development (GO:0072044)3.30693856
65apical protein localization (GO:0045176)3.28378256
66locomotory exploration behavior (GO:0035641)3.27581435
67epithelial tube branching involved in lung morphogenesis (GO:0060441)3.27116733
68negative regulation of cartilage development (GO:0061037)3.26020047
69lateral sprouting from an epithelium (GO:0060601)3.25337159
70midgut development (GO:0007494)3.24355009
71limb development (GO:0060173)3.18827446
72appendage development (GO:0048736)3.18827446
73embryonic cranial skeleton morphogenesis (GO:0048701)3.18476218
74epithelial cilium movement (GO:0003351)3.18276339
75lung lobe morphogenesis (GO:0060463)3.17768649
76positive regulation of mesenchymal cell proliferation (GO:0002053)3.16887964
77lung-associated mesenchyme development (GO:0060484)3.16880118
78regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.16578680
79Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.15622919
80spinal cord development (GO:0021510)3.13772477
81G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.13249720
82negative regulation of fatty acid transport (GO:2000192)3.12818036
83venous blood vessel morphogenesis (GO:0048845)3.12608896
84establishment of nucleus localization (GO:0040023)3.11453642
85regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.10973312
86establishment of planar polarity (GO:0001736)3.10269984
87establishment of tissue polarity (GO:0007164)3.10269984
88cell proliferation involved in metanephros development (GO:0072203)3.08894185
89negative chemotaxis (GO:0050919)3.08749846
90respiratory tube development (GO:0030323)3.07316640
91cell surface receptor signaling pathway involved in heart development (GO:0061311)3.07269537
92regulation of epithelial to mesenchymal transition (GO:0010717)3.03419444
93transmission of nerve impulse (GO:0019226)3.03310306
94regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901213.02657020
95axon extension (GO:0048675)3.02499126
96central nervous system projection neuron axonogenesis (GO:0021952)3.00490542
97regulation of establishment of planar polarity (GO:0090175)2.99596016
98nonmotile primary cilium assembly (GO:0035058)2.98040382
99mechanosensory behavior (GO:0007638)2.98012908
100positive regulation of synapse assembly (GO:0051965)2.94913058
101regulation of mesenchymal cell proliferation (GO:0010464)2.93529866
102sequestering of extracellular ligand from receptor (GO:0035581)2.92271240
103endodermal cell differentiation (GO:0035987)2.91682588
104cranial nerve development (GO:0021545)2.91535510
105embryonic foregut morphogenesis (GO:0048617)2.91401243
106ganglion development (GO:0061548)2.90662328
107cranial nerve morphogenesis (GO:0021602)2.89335230
108collagen metabolic process (GO:0032963)2.88135325
109cilium or flagellum-dependent cell motility (GO:0001539)2.87484283
110cochlea morphogenesis (GO:0090103)2.87124984
111convergent extension (GO:0060026)2.86973728
112cell proliferation involved in kidney development (GO:0072111)2.85351488
113branching involved in salivary gland morphogenesis (GO:0060445)2.85263476
114negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.83586452
115radial glial cell differentiation (GO:0060019)2.82487954
116regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.82378136
117cerebral cortex radially oriented cell migration (GO:0021799)2.82105721
118negative regulation of glial cell proliferation (GO:0060253)2.81927216
119calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.80893310
120outer ear morphogenesis (GO:0042473)2.80706158
121regulation of endothelial cell chemotaxis (GO:2001026)2.80295434
122multicellular organismal macromolecule metabolic process (GO:0044259)2.79785455
123craniofacial suture morphogenesis (GO:0097094)2.79559946
124collagen catabolic process (GO:0030574)2.79362800
125neuronal stem cell maintenance (GO:0097150)2.79061362
126positive regulation of astrocyte differentiation (GO:0048711)2.79025881
127exploration behavior (GO:0035640)2.78976852
128regulation of extracellular matrix organization (GO:1903053)2.78633946
129astrocyte differentiation (GO:0048708)2.78616194
130response to auditory stimulus (GO:0010996)2.78486383
131enteric nervous system development (GO:0048484)2.78171277
132mesenchymal-epithelial cell signaling (GO:0060638)2.76594629
133establishment of apical/basal cell polarity (GO:0035089)2.76046622
134dendrite morphogenesis (GO:0048813)2.75854610
135regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.75717451
136cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.75465790
137nephron tubule development (GO:0072080)2.75318658
138dermatan sulfate biosynthetic process (GO:0030208)2.75210051
139negative regulation of catenin import into nucleus (GO:0035414)2.75005696
140positive regulation of stem cell differentiation (GO:2000738)2.72504665
141regulation of synapse structural plasticity (GO:0051823)2.72344629
142regulation of heart morphogenesis (GO:2000826)2.71893630
143hippo signaling (GO:0035329)2.71584447
144left/right pattern formation (GO:0060972)2.71140732
145substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.70217527
146substrate-independent telencephalic tangential migration (GO:0021826)2.70217527
147cardiac left ventricle morphogenesis (GO:0003214)2.69988961
148renal system development (GO:0072001)2.68959963
149protein localization to synapse (GO:0035418)2.68693710
150somite development (GO:0061053)2.68116130
151somatic stem cell division (GO:0048103)2.67704960
152synapse assembly (GO:0007416)2.67299738
153cellular response to nitric oxide (GO:0071732)2.66428738
154limb bud formation (GO:0060174)2.66066024
155establishment of mitochondrion localization (GO:0051654)2.65981373
156positive regulation of smoothened signaling pathway (GO:0045880)2.64804635
157axis elongation (GO:0003401)2.64782870
158dorsal/ventral neural tube patterning (GO:0021904)2.64124858
159multicellular organismal catabolic process (GO:0044243)2.64041861
160paraxial mesoderm development (GO:0048339)2.62901118
161non-canonical Wnt signaling pathway (GO:0035567)2.62359862
162cell differentiation involved in metanephros development (GO:0072202)2.62159246
163negative regulation of axonogenesis (GO:0050771)2.61961296
164negative regulation of axon extension (GO:0030517)2.60078855
165spinal cord association neuron differentiation (GO:0021527)2.58624742
166olfactory bulb development (GO:0021772)2.56720828
167asymmetric protein localization (GO:0008105)2.56417092
168tongue development (GO:0043586)2.56193164
169neuron fate determination (GO:0048664)2.55854707
170ionotropic glutamate receptor signaling pathway (GO:0035235)2.52928227
171negative regulation of glial cell differentiation (GO:0045686)2.52693659
172midbrain development (GO:0030901)2.51067939
173layer formation in cerebral cortex (GO:0021819)2.50709785
174regulation of glutamate receptor signaling pathway (GO:1900449)2.50357151
175metanephric nephron tubule development (GO:0072234)2.50195759

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.67559264
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.60478599
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.21759667
4EED_16625203_ChIP-ChIP_MESCs_Mouse2.87602201
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.85628307
6EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.68983128
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.65956505
8CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.62154295
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.61212525
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.61212525
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.52627404
12PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.38227457
13* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31639133
14CLOCK_20551151_ChIP-Seq_293T_Human2.29704416
15WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.27003411
16JARID2_20075857_ChIP-Seq_MESCs_Mouse2.26512503
17TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.23634373
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.18463784
19PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.10554547
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.08820356
21TP53_20018659_ChIP-ChIP_R1E_Mouse1.99194782
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.98237095
23EZH2_27304074_Chip-Seq_ESCs_Mouse1.96971825
24STAT6_21828071_ChIP-Seq_BEAS2B_Human1.93198783
25* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.92293775
26TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.89764472
27REST_21632747_ChIP-Seq_MESCs_Mouse1.86007747
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.85272279
29JARID2_20064375_ChIP-Seq_MESCs_Mouse1.85161742
30* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.84549233
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.82294889
32MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80733592
33RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.77536656
34CDX2_20551321_ChIP-Seq_CACO-2_Human1.76821833
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.76128353
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.75119054
37TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.68213321
38EGR1_19374776_ChIP-ChIP_THP-1_Human1.67493392
39KDM2B_26808549_Chip-Seq_K562_Human1.65415284
40EP300_21415370_ChIP-Seq_HL-1_Mouse1.65214979
41ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.63940070
42SUZ12_27294783_Chip-Seq_ESCs_Mouse1.62953115
43EZH2_27294783_Chip-Seq_ESCs_Mouse1.59800494
44RNF2_27304074_Chip-Seq_NSC_Mouse1.59296881
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.57749381
46KDM2B_26808549_Chip-Seq_SUP-B15_Human1.52306771
47ISL1_27105846_Chip-Seq_CPCs_Mouse1.51617033
48ESR1_21235772_ChIP-Seq_MCF-7_Human1.50642146
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.50327161
50NFIB_24661679_ChIP-Seq_LUNG_Mouse1.49633520
51* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.49037920
52* TP53_18474530_ChIP-ChIP_U2OS_Human1.48894504
53NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.47912031
54CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.46806829
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.46769697
56* CJUN_26792858_Chip-Seq_BT549_Human1.46232405
57CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.45307304
58* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.44550903
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.44472637
60GBX2_23144817_ChIP-Seq_PC3_Human1.42542636
61DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.42296485
62BRD4_25478319_ChIP-Seq_HGPS_Human1.40733634
63CBX2_27304074_Chip-Seq_ESCs_Mouse1.39806613
64AHR_22903824_ChIP-Seq_MCF-7_Human1.39706114
65RING1B_27294783_Chip-Seq_ESCs_Mouse1.39164929
66BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38427998
67IKZF1_21737484_ChIP-ChIP_HCT116_Human1.37902306
68HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37537240
69AR_21572438_ChIP-Seq_LNCaP_Human1.37501888
70REST_18959480_ChIP-ChIP_MESCs_Mouse1.36328517
71GATA1_26923725_Chip-Seq_HPCs_Mouse1.34689087
72ESR1_20079471_ChIP-ChIP_T-47D_Human1.34293284
73NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.33038014
74ZFP281_27345836_Chip-Seq_ESCs_Mouse1.32818408
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.32818205
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.32193148
77UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.31306877
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30312378
79HIF1A_21447827_ChIP-Seq_MCF-7_Human1.29486672
80LXR_22292898_ChIP-Seq_THP-1_Human1.29061574
81ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.29024257
82TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.27716586
83EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26750950
84WT1_19549856_ChIP-ChIP_CCG9911_Human1.26736699
85P300_27058665_Chip-Seq_ZR-75-30cells_Human1.25189371
86RACK7_27058665_Chip-Seq_MCF-7_Human1.24282007
87* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24002952
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23801413
89RING1B_27294783_Chip-Seq_NPCs_Mouse1.23795666
90PPAR_26484153_Chip-Seq_NCI-H1993_Human1.23192119
91SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.21822269
92SOX9_24532713_ChIP-Seq_HFSC_Mouse1.20915964
93SOX2_20726797_ChIP-Seq_SW620_Human1.19870711
94CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17805867
95POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17091077
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17091077
97CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16721325
98SMC1_22415368_ChIP-Seq_MEFs_Mouse1.15212359
99CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.14715621
100ARNT_22903824_ChIP-Seq_MCF-7_Human1.14635919
101CTCF_27219007_Chip-Seq_Bcells_Human1.14390065
102DROSHA_22980978_ChIP-Seq_HELA_Human1.13911436
103SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.12885269
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12868923
105TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.11648795
106NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11489996
107NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11489996
108ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.10349132
109STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.10186897
110TBX20_22328084_ChIP-Seq_HEART_Mouse1.09045465
111TBX20_22080862_ChIP-Seq_HEART_Mouse1.09045465
112OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07391119
113TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06531784
114CTBP2_25329375_ChIP-Seq_LNCAP_Human1.05401272
115UBF1/2_26484160_Chip-Seq_HMECs_Human1.05393780
116KDM2B_26808549_Chip-Seq_JURKAT_Human1.04525711
117LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04513640
118* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02582360
119RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.01967104
120CTBP1_25329375_ChIP-Seq_LNCAP_Human1.01267799
121IGF1R_20145208_ChIP-Seq_DFB_Human1.00319699
122SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.97922730
123KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.97812815
124ERG_21242973_ChIP-ChIP_JURKAT_Human0.97746576
125P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95994756
126RARB_27405468_Chip-Seq_BRAIN_Mouse0.95816328
127BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95568231
128RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95342271
129AR_19668381_ChIP-Seq_PC3_Human0.94682914
130EZH2_22144423_ChIP-Seq_EOC_Human0.94416938
131KDM2B_26808549_Chip-Seq_DND41_Human0.93975402
132SMAD3_21741376_ChIP-Seq_EPCs_Human0.92097631
133* POU5F1_16518401_ChIP-PET_MESCs_Mouse0.91284899
134TP63_19390658_ChIP-ChIP_HaCaT_Human0.90794457
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.89971236
136ZFP57_27257070_Chip-Seq_ESCs_Mouse0.89368988
137MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87116720
138SMAD3_21741376_ChIP-Seq_ESCs_Human0.86408179
139POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.86267644
140DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85303037
141SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.83759107
142TBX3_20139965_ChIP-Seq_MESCs_Mouse0.82721908
143SOX3_22085726_ChIP-Seq_NPCs_Mouse0.82450389
144TOP2B_26459242_ChIP-Seq_MCF-7_Human0.82007610
145TBX3_20139965_ChIP-Seq_ESCs_Mouse0.81240066
146SMAD4_21741376_ChIP-Seq_HESCs_Human0.81086704
147CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.80347591
148EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.80336093
149SOX2_21211035_ChIP-Seq_LN229_Gbm0.80252078

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001958_emphysema5.55479073
2MP0008438_abnormal_cutaneous_collagen5.21295468
3MP0004782_abnormal_surfactant_physiolog4.98327308
4MP0000566_synostosis4.27595389
5MP0005275_abnormal_skin_tensile3.75447732
6MP0005503_abnormal_tendon_morphology3.72777254
7MP0010030_abnormal_orbit_morphology3.64201898
8MP0002653_abnormal_ependyma_morphology3.21737806
9MP0005257_abnormal_intraocular_pressure3.06400708
10MP0004859_abnormal_synaptic_plasticity2.64717459
11MP0000537_abnormal_urethra_morphology2.56815654
12MP0009379_abnormal_foot_pigmentation2.55806297
13MP0003136_yellow_coat_color2.42586953
14MP0008995_early_reproductive_senescence2.42325185
15MP0004272_abnormal_basement_membrane2.35167904
16MP0010368_abnormal_lymphatic_system2.34972997
17MP0003705_abnormal_hypodermis_morpholog2.31834139
18MP0003279_aneurysm2.24551355
19MP0003880_abnormal_central_pattern2.23482128
20MP0002295_abnormal_pulmonary_circulatio2.16135055
21MP0003115_abnormal_respiratory_system2.12970426
22MP0004885_abnormal_endolymph2.11850455
23MP0008004_abnormal_stomach_pH2.11633921
24MP0001177_atelectasis2.09127425
25MP0006054_spinal_hemorrhage2.08600887
26MP0005423_abnormal_somatic_nervous1.99563406
27MP0009780_abnormal_chondrocyte_physiolo1.88514450
28MP0001984_abnormal_olfaction1.87599361
29MP0000955_abnormal_spinal_cord1.85549196
30MP0005508_abnormal_skeleton_morphology1.85458503
31MP0002282_abnormal_trachea_morphology1.84421494
32MP0002133_abnormal_respiratory_system1.82542550
33MP0005388_respiratory_system_phenotype1.82542550
34MP0000534_abnormal_ureter_morphology1.77910573
35MP0008789_abnormal_olfactory_epithelium1.76239585
36MP0006276_abnormal_autonomic_nervous1.75073242
37MP0005623_abnormal_meninges_morphology1.71757630
38MP0005499_abnormal_olfactory_system1.70286299
39MP0005394_taste/olfaction_phenotype1.70286299
40MP0000026_abnormal_inner_ear1.68380580
41MP0002638_abnormal_pupillary_reflex1.65975477
42MP0001293_anophthalmia1.65776488
43MP0002822_catalepsy1.63942112
44MP0003635_abnormal_synaptic_transmissio1.63496543
45MP0003385_abnormal_body_wall1.59702232
46MP0009250_abnormal_appendicular_skeleto1.58863437
47MP0009384_cardiac_valve_regurgitation1.54407559
48MP0002734_abnormal_mechanical_nocicepti1.53920003
49MP0004270_analgesia1.53845451
50MP0006292_abnormal_olfactory_placode1.51785771
51MP0003861_abnormal_nervous_system1.51757721
52MP0003942_abnormal_urinary_system1.50793752
53MP0002063_abnormal_learning/memory/cond1.49623200
54MP0002697_abnormal_eye_size1.48785371
55MP0002184_abnormal_innervation1.48591488
56MP0001486_abnormal_startle_reflex1.47672397
57MP0002249_abnormal_larynx_morphology1.41953522
58MP0002882_abnormal_neuron_morphology1.40320835
59MP0002557_abnormal_social/conspecific_i1.40262837
60MP0002152_abnormal_brain_morphology1.40248266
61MP0000631_abnormal_neuroendocrine_gland1.39442604
62MP0005083_abnormal_biliary_tract1.39250455
63MP0001299_abnormal_eye_distance/1.39007021
64MP0000428_abnormal_craniofacial_morphol1.38417386
65MP0005023_abnormal_wound_healing1.37344050
66MP0000049_abnormal_middle_ear1.35973943
67MP0002932_abnormal_joint_morphology1.35419179
68MP0003091_abnormal_cell_migration1.34583319
69MP0001529_abnormal_vocalization1.34314267
70MP0002751_abnormal_autonomic_nervous1.31229005
71MP0002896_abnormal_bone_mineralization1.30412137
72MP0001346_abnormal_lacrimal_gland1.29486777
73MP0002234_abnormal_pharynx_morphology1.28606417
74MP0001502_abnormal_circadian_rhythm1.27140288
75MP0002735_abnormal_chemical_nociception1.26817335
76MP0002572_abnormal_emotion/affect_behav1.23238028
77MP0000762_abnormal_tongue_morphology1.22995123
78MP0002092_abnormal_eye_morphology1.20508770
79MP0002752_abnormal_somatic_nervous1.20163565
80MP0001175_abnormal_lung_morphology1.18910256
81MP0009053_abnormal_anal_canal1.18619740
82MP0001286_abnormal_eye_development1.16671530
83MP0001485_abnormal_pinna_reflex1.15390980
84MP0003890_abnormal_embryonic-extraembry1.14935022
85MP0003329_amyloid_beta_deposits1.14492565
86MP0001879_abnormal_lymphatic_vessel1.14006515
87MP0002060_abnormal_skin_morphology1.13838863
88MP0005409_darkened_coat_color1.13412339
89MP0002064_seizures1.13035128
90MP0005377_hearing/vestibular/ear_phenot1.12108410
91MP0003878_abnormal_ear_physiology1.12108410
92MP0002272_abnormal_nervous_system1.10819323
93MP0004883_abnormal_blood_vessel1.10437167
94MP0001970_abnormal_pain_threshold1.10324423
95MP0002108_abnormal_muscle_morphology1.09982863
96MP0002089_abnormal_postnatal_growth/wei1.09659569
97MP0000733_abnormal_muscle_development1.09176900
98MP0003121_genomic_imprinting1.08287544
99MP0003634_abnormal_glial_cell1.07718196
100MP0003787_abnormal_imprinting1.06087531
101MP0000163_abnormal_cartilage_morphology1.05338550
102MP0001542_abnormal_bone_strength1.05169680
103MP0002277_abnormal_respiratory_mucosa1.05123611
104MP0009745_abnormal_behavioral_response1.04223244
105MP0002938_white_spotting1.04200449
106MP0003755_abnormal_palate_morphology1.02969716
107MP0002233_abnormal_nose_morphology1.02820901
108MP0004134_abnormal_chest_morphology1.01848485
109MP0001963_abnormal_hearing_physiology1.01379356
110MP0004811_abnormal_neuron_physiology1.00989854
111MP0005076_abnormal_cell_differentiation1.00401478
112MP0003283_abnormal_digestive_organ0.99934417
113MP0005391_vision/eye_phenotype0.99192639
114MP0002067_abnormal_sensory_capabilities0.98954303
115MP0002116_abnormal_craniofacial_bone0.97274835
116MP0002733_abnormal_thermal_nociception0.97078864
117MP0004142_abnormal_muscle_tone0.96094430
118MP0002081_perinatal_lethality0.95986923
119MP0005195_abnormal_posterior_eye0.95833600
120MP0000462_abnormal_digestive_system0.95439200
121MP0003935_abnormal_craniofacial_develop0.95290135
122MP0002909_abnormal_adrenal_gland0.93068099
123MP0000767_abnormal_smooth_muscle0.92185570
124MP0000569_abnormal_digit_pigmentation0.91682377
125MP0008961_abnormal_basal_metabolism0.91320039
126MP0003566_abnormal_cell_adhesion0.91130104
127MP0003119_abnormal_digestive_system0.90976941
128MP0001849_ear_inflammation0.90259641
129MP0004133_heterotaxia0.87852540
130MP0002115_abnormal_skeleton_extremities0.87077202
131MP0000647_abnormal_sebaceous_gland0.84876005
132MP0004742_abnormal_vestibular_system0.84855667
133MP0001943_abnormal_respiration0.84758549
134MP0002113_abnormal_skeleton_development0.84142880
135MP0003937_abnormal_limbs/digits/tail_de0.83776974
136MP0004858_abnormal_nervous_system0.80718473
137MP0001243_abnormal_dermal_layer0.79066991
138MP0002998_abnormal_bone_remodeling0.78157977
139MP0003122_maternal_imprinting0.77672401
140MP0000432_abnormal_head_morphology0.76762869
141MP0005390_skeleton_phenotype0.76052804
142MP0002925_abnormal_cardiovascular_devel0.72891483
143MP0002109_abnormal_limb_morphology0.72068264
144MP0005220_abnormal_exocrine_pancreas0.69629821
145MP0005595_abnormal_vascular_smooth0.67335835
146MP0001614_abnormal_blood_vessel0.66384705
147MP0004233_abnormal_muscle_weight0.64137894
148MP0005164_abnormal_response_to0.63920916
149MP0000467_abnormal_esophagus_morphology0.63462960
150MP0002168_other_aberrant_phenotype0.63455054
151MP0001340_abnormal_eyelid_morphology0.63355735
152MP0002128_abnormal_blood_circulation0.63199786
153MP0002177_abnormal_outer_ear0.62261729
154MP0000778_abnormal_nervous_system0.60880362
155MP0002111_abnormal_tail_morphology0.60538485
156MP0005248_abnormal_Harderian_gland0.60304579
157MP0002098_abnormal_vibrissa_morphology0.59394744
158MP0002102_abnormal_ear_morphology0.57990322
159MP0003938_abnormal_ear_development0.57129242
160MP0002933_joint_inflammation0.56937197
161MP0010234_abnormal_vibrissa_follicle0.56859003
162MP0000579_abnormal_nail_morphology0.56735444
163MP0000751_myopathy0.55818617

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.97789683
2Interstitial pulmonary disease (HP:0006530)5.95475972
3Premature rupture of membranes (HP:0001788)5.17031258
4Ankle contracture (HP:0006466)4.94921028
5Neonatal short-limb short stature (HP:0008921)4.91562023
6Shallow orbits (HP:0000586)4.53251744
7Broad metatarsal (HP:0001783)4.44556603
8Atrophic scars (HP:0001075)4.07629071
9Coronal craniosynostosis (HP:0004440)3.94322050
10Abnormal respiratory epithelium morphology (HP:0012253)3.53359651
11Abnormal respiratory motile cilium morphology (HP:0005938)3.53359651
12Aortic dissection (HP:0002647)3.51212004
13Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.49386380
14Abnormal ciliary motility (HP:0012262)3.45295288
15Follicular hyperkeratosis (HP:0007502)3.44531543
16Abnormal respiratory motile cilium physiology (HP:0012261)3.30051859
17Hallux valgus (HP:0001822)3.23271777
18Deviation of the hallux (HP:0010051)3.21710910
19Cerebral aneurysm (HP:0004944)3.21302751
20Abnormality of the 4th metacarpal (HP:0010012)3.20043411
21Dynein arm defect of respiratory motile cilia (HP:0012255)3.14134667
22Absent/shortened dynein arms (HP:0200106)3.14134667
23Abnormality of dentin (HP:0010299)3.12631589
24Bladder diverticulum (HP:0000015)3.11748951
25Aplasia involving bones of the upper limbs (HP:0009823)3.11200434
26Aplasia of the phalanges of the hand (HP:0009802)3.11200434
27Aplasia involving bones of the extremities (HP:0009825)3.11200434
28Septo-optic dysplasia (HP:0100842)3.09126268
29Soft skin (HP:0000977)3.06323142
30Type 1 muscle fiber predominance (HP:0003803)3.00425090
31Aortic aneurysm (HP:0004942)2.92516882
32Peritonitis (HP:0002586)2.90307509
33Tubulointerstitial fibrosis (HP:0005576)2.89332603
34Vitreoretinal degeneration (HP:0000655)2.88448942
35Ulnar bowing (HP:0003031)2.85712995
36Rhinitis (HP:0012384)2.83348797
37Mildly elevated creatine phosphokinase (HP:0008180)2.81739821
38Mitral valve prolapse (HP:0001634)2.75790408
39Bronchomalacia (HP:0002780)2.73496511
40Respiratory distress (HP:0002098)2.69904543
41Abnormality of the diencephalon (HP:0010662)2.68328783
42Anophthalmia (HP:0000528)2.67524433
43Partial duplication of the phalanx of hand (HP:0009999)2.62959311
44Wrist flexion contracture (HP:0001239)2.62716316
45Cutaneous finger syndactyly (HP:0010554)2.62390265
46Myokymia (HP:0002411)2.60430450
47Vascular tortuosity (HP:0004948)2.55820760
48Fragile skin (HP:0001030)2.55566306
49Hyperextensible skin (HP:0000974)2.55390001
50Spinal rigidity (HP:0003306)2.54134645
51Slender build (HP:0001533)2.53007764
52Arterial tortuosity (HP:0005116)2.50676628
53Hepatoblastoma (HP:0002884)2.50607793
54Dilatation of the ascending aorta (HP:0005111)2.49055744
55Wormian bones (HP:0002645)2.47789673
56Cutaneous syndactyly (HP:0012725)2.46366761
57Wide anterior fontanel (HP:0000260)2.46217193
58Infantile muscular hypotonia (HP:0008947)2.46157280
59Rib fusion (HP:0000902)2.45612937
60Biconcave vertebral bodies (HP:0004586)2.43847088
61Megalencephaly (HP:0001355)2.43829770
62Turricephaly (HP:0000262)2.43299762
63Tachypnea (HP:0002789)2.41788641
64Hypoventilation (HP:0002791)2.40408354
65Camptodactyly of toe (HP:0001836)2.40298145
66Blue sclerae (HP:0000592)2.36432190
67Renal dysplasia (HP:0000110)2.31231759
68Long toe (HP:0010511)2.27528742
69Vertebral compression fractures (HP:0002953)2.24455639
70Increased variability in muscle fiber diameter (HP:0003557)2.23837427
71Abnormality of the right ventricle (HP:0001707)2.22643639
72Nephronophthisis (HP:0000090)2.22396173
73Renal hypoplasia (HP:0000089)2.18848918
74Intestinal atresia (HP:0011100)2.16919443
75Genu recurvatum (HP:0002816)2.15593410
76Occipital encephalocele (HP:0002085)2.14454406
77Alacrima (HP:0000522)2.14027140
78Esophageal atresia (HP:0002032)2.13723468
79Neonatal respiratory distress (HP:0002643)2.11927825
80Broad toe (HP:0001837)2.11923703
81Midline defect of the nose (HP:0004122)2.11002586
82True hermaphroditism (HP:0010459)2.10603774
83Renovascular hypertension (HP:0100817)2.09551307
84Abnormality of the aortic arch (HP:0012303)2.08839878
85Visceral angiomatosis (HP:0100761)2.08818293
86Buphthalmos (HP:0000557)2.08704409
87Broad hallux (HP:0010055)2.05831496
88Trigonocephaly (HP:0000243)2.04549174
89Striae distensae (HP:0001065)2.03770599
90Bell-shaped thorax (HP:0001591)2.03490097
91Split foot (HP:0001839)2.03247354
92Adactyly (HP:0009776)2.02719235
93Partial duplication of thumb phalanx (HP:0009944)2.02653447
94Bowel diverticulosis (HP:0005222)2.01013431
95Fibular hypoplasia (HP:0003038)2.00556640
96Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.99917401
97Osteoarthritis (HP:0002758)1.99766722
98Oligodactyly (HP:0012165)1.98937453
99Abnormality of the middle phalanges of the toes (HP:0010183)1.98375692
100Oligodactyly (hands) (HP:0001180)1.98250347
101Narrow nasal bridge (HP:0000446)1.98016963
102Increased connective tissue (HP:0009025)1.96995526
103Mitral regurgitation (HP:0001653)1.96550997
104Maternal diabetes (HP:0009800)1.95920886
105Cortical dysplasia (HP:0002539)1.95759574
106Hyperactive renin-angiotensin system (HP:0000841)1.94813526
107Aneurysm (HP:0002617)1.92879376
108Tarsal synostosis (HP:0008368)1.92523725
109Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.91801232
110Short 4th metacarpal (HP:0010044)1.91801232
111Renal duplication (HP:0000075)1.91460621
112Overriding aorta (HP:0002623)1.91079903
113Renal salt wasting (HP:0000127)1.90880830
114Hemangiomatosis (HP:0007461)1.90856344
115Bowed forearm bones (HP:0003956)1.90534509
116Bowing of the arm (HP:0006488)1.90534509
117Arnold-Chiari malformation (HP:0002308)1.90483314
118Cervical subluxation (HP:0003308)1.90332014
119Thickened helices (HP:0000391)1.88609993
120Abnormality of the ischium (HP:0003174)1.88546824
121Femoral bowing (HP:0002980)1.87171063
122Vaginal atresia (HP:0000148)1.86780449
123Abnormality of the parietal bone (HP:0002696)1.86258892
124Abnormality of skeletal muscle fiber size (HP:0012084)1.86042358
125Abnormality of midbrain morphology (HP:0002418)1.85986630
126Molar tooth sign on MRI (HP:0002419)1.85986630
127Osteolytic defects of the phalanges of the hand (HP:0009771)1.85885961
128Osteolytic defects of the hand bones (HP:0009699)1.85885961
129Aplasia cutis congenita (HP:0001057)1.85759870
130Overgrowth (HP:0001548)1.85219080
131Joint laxity (HP:0001388)1.84984677
132High anterior hairline (HP:0009890)1.84958852
133Down-sloping shoulders (HP:0200021)1.84166368
134Protruding ear (HP:0000411)1.83745868
135Chronic hepatic failure (HP:0100626)1.82537637
136Spondylolisthesis (HP:0003302)1.80591730
137Vertebral arch anomaly (HP:0008438)1.80291869
138Abnormality of the phalanges of the 2nd finger (HP:0009541)1.80229601
139Joint contractures involving the joints of the feet (HP:0100492)1.79784164
140Flexion contracture of toe (HP:0005830)1.79784164
141Germ cell neoplasia (HP:0100728)1.79409528
142Abnormality of the 2nd finger (HP:0004100)1.78958488
143Broad ribs (HP:0000885)1.77559120
144Gait imbalance (HP:0002141)1.77005737
145Tibial bowing (HP:0002982)1.76367572
146Broad long bones (HP:0005622)1.76226058
147Elfin facies (HP:0004428)1.75950448
148Genital tract atresia (HP:0001827)1.75885915
149Abnormality of the renal medulla (HP:0100957)1.74134741
150Shawl scrotum (HP:0000049)1.73996094
151Broad finger (HP:0001500)1.73595841
152Morphological abnormality of the middle ear (HP:0008609)1.73163159
153Flat cornea (HP:0007720)1.72604052
154Sleep apnea (HP:0010535)1.71843324
155Gastrointestinal atresia (HP:0002589)1.71824135
156Broad phalanx (HP:0006009)1.71580843
157Optic nerve hypoplasia (HP:0000609)1.70189473
158Synostosis of carpal bones (HP:0005048)1.69559676
159Broad phalanges of the hand (HP:0009768)1.69532611
160Broad thumb (HP:0011304)1.69343238
161Missing ribs (HP:0000921)1.69063705
162Anencephaly (HP:0002323)1.68816035
163Postaxial hand polydactyly (HP:0001162)1.68411817
164Hyperacusis (HP:0010780)1.68185709
165Hypoplasia of the ulna (HP:0003022)1.66934547
166Omphalocele (HP:0001539)1.66257978
167Polyphagia (HP:0002591)1.66220677
168Pancreatic fibrosis (HP:0100732)1.66075438
169Abnormality of the intervertebral disk (HP:0005108)1.62275715
170Hemivertebrae (HP:0002937)1.61132360
171Abnormal number of incisors (HP:0011064)1.61094772
172Tracheomalacia (HP:0002779)1.60100602
173Atelectasis (HP:0100750)1.59873715
174Postaxial foot polydactyly (HP:0001830)1.59684421
175Increased corneal curvature (HP:0100692)1.58269302
176Keratoconus (HP:0000563)1.58269302
177Sacral dimple (HP:0000960)1.57716681

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FGFR25.36596099
2MARK14.50643447
3TRIB33.83646379
4EPHB23.81526750
5PDGFRA3.74876280
6DDR23.61306370
7NTRK32.67069124
8FGFR32.60898380
9ERN12.58953877
10TYRO32.58006152
11LATS22.53681583
12FGFR42.33842783
13FGFR12.26447319
14PNCK2.22949436
15DYRK22.22662642
16PAK42.15501188
17ILK2.06051910
18EPHA32.05350783
19PDGFRB1.95148157
20RIPK11.95070901
21LRRK21.94781349
22EPHA41.81446371
23MAP3K41.79462574
24TGFBR21.67719422
25SIK11.67533831
26LATS11.62621003
27MAP3K101.57750830
28FER1.56307553
29TNIK1.56059361
30TLK11.53694318
31MAP2K71.52990340
32PRKD31.52317820
33BUB11.51999379
34DAPK21.51662360
35PTK61.51251715
36KSR11.44713332
37CDK81.40759367
38TIE11.39979745
39MELK1.37675708
40STK241.37440817
41EPHB11.36721123
42DMPK1.32562951
43TTN1.27655145
44ROCK21.27113634
45BMX1.25058283
46SGK2231.18106434
47SGK4941.18106434
48PKN21.15914340
49CDC42BPA1.06846218
50CSNK1G21.05105658
51PTK21.03505795
52ROCK11.02023971
53DYRK1A1.00661980
54MINK10.98737184
55MKNK20.97811494
56SIK30.95627623
57MAPK130.94261855
58ICK0.91895415
59PRKCG0.91640186
60RPS6KA40.89109014
61CDK50.88363966
62PAK20.87490480
63SIK20.86690118
64PAK60.86638785
65SGK20.85940178
66CASK0.85867157
67MKNK10.85811772
68MOS0.84933759
69MAP3K70.83578063
70WNK10.83144630
71ERBB20.81086145
72PKN10.78782546
73ZAP700.78290999
74RPS6KA20.77657670
75PRKD10.77336613
76RET0.76699938
77LIMK10.76215414
78BCR0.75569591
79LMTK20.75042179
80CAMK1D0.73384087
81NTRK20.73137943
82PRKCH0.71469679
83PTK2B0.71352401
84UHMK10.69996704
85CAMKK10.69926723
86CDK11A0.69731701
87CDK150.68990983
88STK110.68828337
89MAP2K40.68311700
90MET0.66715742
91CDK180.64881137
92DAPK30.62147901
93CDK140.61901766
94EPHA20.59473625
95MTOR0.59446127
96CAMK1G0.59125493
97CDK30.58183137
98MST1R0.54358389
99DYRK30.54130660
100TESK10.51570228
101PIK3CA0.50421644
102EEF2K0.48653413
103CDK190.48394724
104GSK3A0.47959872
105PRKCZ0.47090078
106WNK40.46987885
107STK390.46568413
108NEK90.44661459
109CSNK1G10.44181555
110CSNK1G30.43550412
111TGFBR10.43345271
112CDK60.42370309
113ADRBK20.40528373
114CAMK2A0.39818813
115CSNK1E0.38936904
116TAOK20.38857252
117INSRR0.38658576
118KSR20.37983698
119SGK10.37091456
120MAPK100.37055227
121SGK30.36398937
122SRC0.35984618
123BRD40.35878371
124NTRK10.35856946
125CAMK2B0.35671349
126PRKDC0.35551437
127MAP2K20.35027255
128PLK20.34914500
129CHUK0.34899459
130CAMK10.34622006
131STK38L0.34529837
132AKT20.34084993
133MAP3K20.33849060
134WNK30.33518131
135MAP2K10.33156981
136MAPK90.32393065
137CSNK1A1L0.31124145
138MARK20.31067128
139BRSK10.30223015
140PAK30.29335576
141CSK0.29128774
142INSR0.28781847
143ADRBK10.26855026
144AURKA0.26520295
145EGFR0.26168704
146MAPK150.23943962
147PAK10.23812829
148DYRK1B0.22163283
149STK30.21674024
150PRKD20.20962863
151STK100.20705593
152CAMK40.18306012
153HIPK20.17689382
154PRKCE0.17222100

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.62136171
2Basal cell carcinoma_Homo sapiens_hsa052172.90236087
3Notch signaling pathway_Homo sapiens_hsa043302.83383650
4Bladder cancer_Homo sapiens_hsa052192.42601880
5Focal adhesion_Homo sapiens_hsa045102.40209238
6Nicotine addiction_Homo sapiens_hsa050332.38917456
7Hedgehog signaling pathway_Homo sapiens_hsa043402.31970632
8Hippo signaling pathway_Homo sapiens_hsa043902.30888726
9Axon guidance_Homo sapiens_hsa043602.22977976
10Adherens junction_Homo sapiens_hsa045202.18637771
11AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.17435487
12Proteoglycans in cancer_Homo sapiens_hsa052052.09787789
13Glutamatergic synapse_Homo sapiens_hsa047241.96397007
14Protein digestion and absorption_Homo sapiens_hsa049741.82551250
15MicroRNAs in cancer_Homo sapiens_hsa052061.75905858
16GABAergic synapse_Homo sapiens_hsa047271.75468520
17TGF-beta signaling pathway_Homo sapiens_hsa043501.73464795
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.66059561
19Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.64562661
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.64052446
21Amoebiasis_Homo sapiens_hsa051461.62541157
22Cholinergic synapse_Homo sapiens_hsa047251.62036301
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.59683222
24Morphine addiction_Homo sapiens_hsa050321.57914278
25Dorso-ventral axis formation_Homo sapiens_hsa043201.51265726
26Dopaminergic synapse_Homo sapiens_hsa047281.49419480
27Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.45394243
28Mineral absorption_Homo sapiens_hsa049781.43755423
29Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.40391945
30Wnt signaling pathway_Homo sapiens_hsa043101.40329713
31Insulin secretion_Homo sapiens_hsa049111.39305302
32Tight junction_Homo sapiens_hsa045301.38982940
33Prion diseases_Homo sapiens_hsa050201.38677888
34Small cell lung cancer_Homo sapiens_hsa052221.34889573
35Cardiac muscle contraction_Homo sapiens_hsa042601.34462727
36Melanogenesis_Homo sapiens_hsa049161.31478561
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.31201179
38Chronic myeloid leukemia_Homo sapiens_hsa052201.29166695
39Amphetamine addiction_Homo sapiens_hsa050311.28209647
40Rap1 signaling pathway_Homo sapiens_hsa040151.27136545
41PI3K-Akt signaling pathway_Homo sapiens_hsa041511.26363538
42Malaria_Homo sapiens_hsa051441.22998587
43cAMP signaling pathway_Homo sapiens_hsa040241.21643030
44Pathways in cancer_Homo sapiens_hsa052001.20500135
45Renal cell carcinoma_Homo sapiens_hsa052111.19959623
46Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.19496364
47Melanoma_Homo sapiens_hsa052181.19306958
48Leukocyte transendothelial migration_Homo sapiens_hsa046701.16507938
49Phagosome_Homo sapiens_hsa041451.16433390
50Glioma_Homo sapiens_hsa052141.15528502
51Dilated cardiomyopathy_Homo sapiens_hsa054141.15439558
52Regulation of actin cytoskeleton_Homo sapiens_hsa048101.12932851
53VEGF signaling pathway_Homo sapiens_hsa043701.07469663
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07434917
55Estrogen signaling pathway_Homo sapiens_hsa049151.07118858
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.06928577
57Gap junction_Homo sapiens_hsa045401.05043839
58Central carbon metabolism in cancer_Homo sapiens_hsa052301.04258604
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02474113
60Endometrial cancer_Homo sapiens_hsa052131.01972420
61Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.01676392
62Pancreatic cancer_Homo sapiens_hsa052121.01287282
63Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00824813
64Colorectal cancer_Homo sapiens_hsa052101.00532842
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.96686866
66Lysosome_Homo sapiens_hsa041420.96315267
67Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95197597
68Vibrio cholerae infection_Homo sapiens_hsa051100.92043258
69Serotonergic synapse_Homo sapiens_hsa047260.90983820
70Synaptic vesicle cycle_Homo sapiens_hsa047210.90508714
71Platelet activation_Homo sapiens_hsa046110.89620068
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.86642756
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86545735
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86290290
75Aldosterone synthesis and secretion_Homo sapiens_hsa049250.85322198
76Bile secretion_Homo sapiens_hsa049760.84148937
77Endocytosis_Homo sapiens_hsa041440.83175275
78GnRH signaling pathway_Homo sapiens_hsa049120.81242126
79Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80297665
80Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79701015
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79281834
82Long-term potentiation_Homo sapiens_hsa047200.79014390
83HTLV-I infection_Homo sapiens_hsa051660.78891794
84ErbB signaling pathway_Homo sapiens_hsa040120.78785007
85Prostate cancer_Homo sapiens_hsa052150.78761068
86Phototransduction_Homo sapiens_hsa047440.75427745
87Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.74606216
88Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.74560112
89Non-small cell lung cancer_Homo sapiens_hsa052230.73265415
90Viral myocarditis_Homo sapiens_hsa054160.72832091
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71470349
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.69466216
93Renin-angiotensin system_Homo sapiens_hsa046140.68922081
94Toxoplasmosis_Homo sapiens_hsa051450.66628919
95Gastric acid secretion_Homo sapiens_hsa049710.66413778
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.64033791
97Choline metabolism in cancer_Homo sapiens_hsa052310.62896708
98Alcoholism_Homo sapiens_hsa050340.62782300
99Histidine metabolism_Homo sapiens_hsa003400.61744310
100Linoleic acid metabolism_Homo sapiens_hsa005910.61344508
101Ras signaling pathway_Homo sapiens_hsa040140.61278593
102mTOR signaling pathway_Homo sapiens_hsa041500.60448096
103Renin secretion_Homo sapiens_hsa049240.60417464
104Pancreatic secretion_Homo sapiens_hsa049720.60092876
105Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.57854090
106TNF signaling pathway_Homo sapiens_hsa046680.57443817
107Calcium signaling pathway_Homo sapiens_hsa040200.56452299
108Pertussis_Homo sapiens_hsa051330.56207381
109Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.56204939
110Thyroid hormone synthesis_Homo sapiens_hsa049180.56168106
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56155838
112Long-term depression_Homo sapiens_hsa047300.55209858
113MAPK signaling pathway_Homo sapiens_hsa040100.55174974
114Salivary secretion_Homo sapiens_hsa049700.54083627
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.53631733
116Fatty acid biosynthesis_Homo sapiens_hsa000610.53512189
117Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53442091
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.52664606
119Cyanoamino acid metabolism_Homo sapiens_hsa004600.49411528
120Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48712649
121Fat digestion and absorption_Homo sapiens_hsa049750.48220178
122Thyroid cancer_Homo sapiens_hsa052160.47549847
123Shigellosis_Homo sapiens_hsa051310.47467213
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45482115
125Oxytocin signaling pathway_Homo sapiens_hsa049210.45063710
126Apoptosis_Homo sapiens_hsa042100.44985404
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44562336
128beta-Alanine metabolism_Homo sapiens_hsa004100.43682638
129Taste transduction_Homo sapiens_hsa047420.43346842
130Circadian entrainment_Homo sapiens_hsa047130.43101831
131Cocaine addiction_Homo sapiens_hsa050300.42654126
132Nitrogen metabolism_Homo sapiens_hsa009100.41305827
133Type II diabetes mellitus_Homo sapiens_hsa049300.40684328
134Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.39551783
135Caffeine metabolism_Homo sapiens_hsa002320.38249287
136Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37634820
137Ribosome_Homo sapiens_hsa030100.36988578

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