Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.27612700 |
2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.23771685 |
3 | negative regulation of cell killing (GO:0031342) | 5.23771685 |
4 | definitive hemopoiesis (GO:0060216) | 4.85335195 |
5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.45704110 |
6 | positive regulation of B cell differentiation (GO:0045579) | 4.39067640 |
7 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.14010674 |
8 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.14010674 |
9 | immunoglobulin mediated immune response (GO:0016064) | 4.05138308 |
10 | neutrophil activation involved in immune response (GO:0002283) | 3.86493597 |
11 | megakaryocyte development (GO:0035855) | 3.83777299 |
12 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.75852059 |
13 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.73168743 |
14 | mast cell activation (GO:0045576) | 3.70151435 |
15 | activated T cell proliferation (GO:0050798) | 3.65636526 |
16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.61539777 |
17 | negative regulation of interleukin-12 production (GO:0032695) | 3.59657893 |
18 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.50304556 |
19 | detection of other organism (GO:0098543) | 3.47151054 |
20 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.44418692 |
21 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.44301705 |
22 | regulation of B cell differentiation (GO:0045577) | 3.43426925 |
23 | B cell receptor signaling pathway (GO:0050853) | 3.39558608 |
24 | amyloid precursor protein catabolic process (GO:0042987) | 3.39412588 |
25 | ribosomal small subunit assembly (GO:0000028) | 3.37640703 |
26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.36393710 |
27 | negative regulation of granulocyte differentiation (GO:0030853) | 3.35480552 |
28 | regulation of T cell tolerance induction (GO:0002664) | 3.34558735 |
29 | response to peptidoglycan (GO:0032494) | 3.33931701 |
30 | angiogenesis involved in wound healing (GO:0060055) | 3.32607892 |
31 | negative regulation of T cell mediated immunity (GO:0002710) | 3.32468216 |
32 | negative thymic T cell selection (GO:0045060) | 3.32406509 |
33 | detection of bacterium (GO:0016045) | 3.31014459 |
34 | response to muramyl dipeptide (GO:0032495) | 3.29122024 |
35 | germinal center formation (GO:0002467) | 3.28681237 |
36 | pinocytosis (GO:0006907) | 3.26053956 |
37 | negative T cell selection (GO:0043383) | 3.25619469 |
38 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.19853929 |
39 | negative regulation of phagocytosis (GO:0050765) | 3.19088730 |
40 | phagocytosis, engulfment (GO:0006911) | 3.18027314 |
41 | regulation of regulatory T cell differentiation (GO:0045589) | 3.16957513 |
42 | B cell mediated immunity (GO:0019724) | 3.16633284 |
43 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.16351452 |
44 | response to interferon-beta (GO:0035456) | 3.15381299 |
45 | regulation of gamma-delta T cell activation (GO:0046643) | 3.12234047 |
46 | platelet dense granule organization (GO:0060155) | 3.10751850 |
47 | interferon-gamma secretion (GO:0072643) | 3.10424107 |
48 | hepatocyte apoptotic process (GO:0097284) | 3.09637394 |
49 | regulation of tolerance induction (GO:0002643) | 3.02587806 |
50 | positive regulation of tolerance induction (GO:0002645) | 2.99797728 |
51 | cellular extravasation (GO:0045123) | 2.96684958 |
52 | T cell selection (GO:0045058) | 2.96577102 |
53 | response to interleukin-15 (GO:0070672) | 2.95821236 |
54 | macrophage differentiation (GO:0030225) | 2.92571455 |
55 | myeloid dendritic cell activation (GO:0001773) | 2.91814824 |
56 | mast cell degranulation (GO:0043303) | 2.89891302 |
57 | mast cell activation involved in immune response (GO:0002279) | 2.89891302 |
58 | thymic T cell selection (GO:0045061) | 2.89664647 |
59 | myeloid cell activation involved in immune response (GO:0002275) | 2.88666887 |
60 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.87490229 |
61 | detection of external biotic stimulus (GO:0098581) | 2.84613695 |
62 | positive regulation of antigen processing and presentation (GO:0002579) | 2.81871272 |
63 | response to protozoan (GO:0001562) | 2.81807341 |
64 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.81163541 |
65 | negative regulation of interleukin-6 production (GO:0032715) | 2.79896935 |
66 | respiratory burst (GO:0045730) | 2.79896209 |
67 | neutrophil activation (GO:0042119) | 2.79187400 |
68 | positive regulation by symbiont of host defense response (GO:0052509) | 2.79076619 |
69 | modulation by symbiont of host defense response (GO:0052031) | 2.79076619 |
70 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.79076619 |
71 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.79076619 |
72 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.79076619 |
73 | modulation by symbiont of host immune response (GO:0052553) | 2.79076619 |
74 | lymphoid progenitor cell differentiation (GO:0002320) | 2.77464726 |
75 | positive thymic T cell selection (GO:0045059) | 2.74396259 |
76 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.74044090 |
77 | negative regulation of innate immune response (GO:0045824) | 2.71102091 |
78 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.70538309 |
79 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.70538309 |
80 | amyloid precursor protein metabolic process (GO:0042982) | 2.69989704 |
81 | macrophage activation involved in immune response (GO:0002281) | 2.68984236 |
82 | response to type I interferon (GO:0034340) | 2.66461031 |
83 | germ cell migration (GO:0008354) | 2.65578384 |
84 | detection of molecule of bacterial origin (GO:0032490) | 2.64415528 |
85 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.63919662 |
86 | viral transcription (GO:0019083) | 2.63456136 |
87 | defense response to protozoan (GO:0042832) | 2.63117249 |
88 | response to laminar fluid shear stress (GO:0034616) | 2.62625392 |
89 | leukocyte aggregation (GO:0070486) | 2.62443839 |
90 | mature B cell differentiation involved in immune response (GO:0002313) | 2.61392853 |
91 | mannose metabolic process (GO:0006013) | 2.60841953 |
92 | macrophage activation (GO:0042116) | 2.60447793 |
93 | cellular response to interleukin-15 (GO:0071350) | 2.59802783 |
94 | myeloid leukocyte activation (GO:0002274) | 2.59399310 |
95 | positive T cell selection (GO:0043368) | 2.58019896 |
96 | detection of biotic stimulus (GO:0009595) | 2.57856448 |
97 | endothelium development (GO:0003158) | 2.57629713 |
98 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.57581968 |
99 | cellular response to type I interferon (GO:0071357) | 2.57324062 |
100 | type I interferon signaling pathway (GO:0060337) | 2.57324062 |
101 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.55433973 |
102 | response to host (GO:0075136) | 2.55433973 |
103 | response to host defenses (GO:0052200) | 2.55433973 |
104 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.54775854 |
105 | response to host immune response (GO:0052572) | 2.54775854 |
106 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.54768339 |
107 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.53978317 |
108 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.53529106 |
109 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.52264857 |
110 | interferon-gamma production (GO:0032609) | 2.52131652 |
111 | microglial cell activation (GO:0001774) | 2.52117503 |
112 | embryonic hemopoiesis (GO:0035162) | 2.49627591 |
113 | negative regulation of interleukin-1 production (GO:0032692) | 2.49337719 |
114 | leukocyte degranulation (GO:0043299) | 2.48391724 |
115 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.48219121 |
116 | membrane protein intracellular domain proteolysis (GO:0031293) | 2.48046913 |
117 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.45968312 |
118 | membrane invagination (GO:0010324) | 2.45952271 |
119 | positive regulation of mast cell activation (GO:0033005) | 2.45776092 |
120 | regulation of mast cell degranulation (GO:0043304) | 2.45534169 |
121 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.44264603 |
122 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.43787615 |
123 | Notch receptor processing (GO:0007220) | 2.43611284 |
124 | T cell homeostasis (GO:0043029) | 2.42621034 |
125 | translational termination (GO:0006415) | 2.42563931 |
126 | dendritic cell migration (GO:0036336) | 2.42549365 |
127 | serine transport (GO:0032329) | 2.42293304 |
128 | regulation of leukocyte degranulation (GO:0043300) | 2.42101190 |
129 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.41769354 |
130 | dendritic cell chemotaxis (GO:0002407) | 2.41757000 |
131 | myeloid cell development (GO:0061515) | 2.41639201 |
132 | leukocyte homeostasis (GO:0001776) | 2.41482413 |
133 | myeloid dendritic cell differentiation (GO:0043011) | 2.40791059 |
134 | axon ensheathment in central nervous system (GO:0032291) | 2.39048368 |
135 | central nervous system myelination (GO:0022010) | 2.39048368 |
136 | dendritic cell differentiation (GO:0097028) | 2.37921593 |
137 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.37017359 |
138 | granulocyte activation (GO:0036230) | 2.36019575 |
139 | leukocyte cell-cell adhesion (GO:0007159) | 2.35479750 |
140 | secretory granule organization (GO:0033363) | 2.35256383 |
141 | regulation of mast cell activation (GO:0033003) | 2.34554249 |
142 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.33712587 |
143 | regulation of antigen processing and presentation (GO:0002577) | 2.32976964 |
144 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.32455256 |
145 | signal complex assembly (GO:0007172) | 2.32410920 |
146 | lymphocyte homeostasis (GO:0002260) | 2.32181995 |
147 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.31777482 |
148 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.31215674 |
149 | regulation of granulocyte differentiation (GO:0030852) | 2.30805182 |
150 | negative regulation of B cell proliferation (GO:0030889) | 2.29068711 |
151 | polyketide metabolic process (GO:0030638) | 2.28681022 |
152 | doxorubicin metabolic process (GO:0044598) | 2.28681022 |
153 | daunorubicin metabolic process (GO:0044597) | 2.28681022 |
154 | positive regulation of chemokine secretion (GO:0090197) | 2.27681666 |
155 | establishment of endothelial barrier (GO:0061028) | 2.26681280 |
156 | negative regulation of stress fiber assembly (GO:0051497) | 2.26468504 |
157 | positive regulation of vasculogenesis (GO:2001214) | 2.26249356 |
158 | T cell migration (GO:0072678) | 2.26173205 |
159 | tolerance induction (GO:0002507) | 2.26029909 |
160 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 2.25423681 |
161 | endosome to pigment granule transport (GO:0043485) | 2.24081038 |
162 | endosome to melanosome transport (GO:0035646) | 2.24081038 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SCL_19346495_ChIP-Seq_HPC-7_Human | 4.51845205 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.96623393 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.73520036 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.62026657 |
5 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.51419777 |
6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.25034739 |
7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.05256889 |
8 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.93434100 |
9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.92883199 |
10 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.80432743 |
11 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.75139395 |
12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.73693845 |
13 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.71495208 |
14 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.70670471 |
15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.66424705 |
16 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.63785036 |
17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.53411893 |
18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.47717165 |
19 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.46619864 |
20 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.42272357 |
21 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.37014394 |
22 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.29886126 |
23 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.26628431 |
24 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.25224757 |
25 | MYC_22102868_ChIP-Seq_BL_Human | 2.12293626 |
26 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.06830508 |
27 | MYB_26560356_Chip-Seq_TH2_Human | 2.04298842 |
28 | * MAF_26560356_Chip-Seq_TH1_Human | 1.98660840 |
29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92804790 |
30 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.92791399 |
31 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.88796801 |
32 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.85056220 |
33 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83711032 |
34 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.83551042 |
35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81929424 |
36 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.81439423 |
37 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.81177308 |
38 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.75701675 |
39 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.75142708 |
40 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.74691573 |
41 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.72854492 |
42 | MYB_26560356_Chip-Seq_TH1_Human | 1.70130406 |
43 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.68681394 |
44 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.68122601 |
45 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.66530350 |
46 | SPI1_23127762_ChIP-Seq_K562_Human | 1.65481145 |
47 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.65474773 |
48 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.63753084 |
49 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.62213372 |
50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.59667726 |
51 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.59651797 |
52 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59469748 |
53 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.59136329 |
54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.58284142 |
55 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.55448464 |
56 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.54784764 |
57 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.54212045 |
58 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48826806 |
59 | GATA1_22025678_ChIP-Seq_K562_Human | 1.48714078 |
60 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.45679553 |
61 | KDM2B_26808549_Chip-Seq_K562_Human | 1.44223129 |
62 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.43742390 |
63 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.42636101 |
64 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.42007689 |
65 | * GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.41113423 |
66 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.39594469 |
67 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.31030569 |
68 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.29003571 |
69 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.28982721 |
70 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.28384103 |
71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27870617 |
72 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.27679370 |
73 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.26494494 |
74 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.23775961 |
75 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.21211797 |
76 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.20951318 |
77 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.19287346 |
78 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.17256050 |
79 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.15227929 |
80 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.14684029 |
81 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14643807 |
82 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.13979796 |
83 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.13037319 |
84 | GATA1_19941826_ChIP-Seq_K562_Human | 1.11230696 |
85 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.09993676 |
86 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.09527145 |
87 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.09156574 |
88 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06118146 |
89 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.05932179 |
90 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.05689687 |
91 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.05514768 |
92 | MAF_26560356_Chip-Seq_TH2_Human | 1.04599086 |
93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03624812 |
94 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.01766936 |
95 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.01081263 |
96 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.00523918 |
97 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.00471104 |
98 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99224363 |
99 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.98278280 |
100 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.98249426 |
101 | * KDM2B_26808549_Chip-Seq_DND41_Human | 0.97944734 |
102 | P68_20966046_ChIP-Seq_HELA_Human | 0.96030447 |
103 | GATA2_19941826_ChIP-Seq_K562_Human | 0.95336802 |
104 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.94947075 |
105 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.94801204 |
106 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.94057275 |
107 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.93223404 |
108 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.92933411 |
109 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92627737 |
110 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.91128274 |
111 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.89842602 |
112 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88259067 |
113 | GATA3_26560356_Chip-Seq_TH2_Human | 0.88082510 |
114 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.87654322 |
115 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.87550507 |
116 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.86749756 |
117 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.86602830 |
118 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.86095861 |
119 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.84419210 |
120 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.83955067 |
121 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.83943358 |
122 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.83119048 |
123 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.82970953 |
124 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.82045464 |
125 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.82045464 |
126 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.82045464 |
127 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.81017307 |
128 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.80945962 |
129 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.79913038 |
130 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.78826606 |
131 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.78514257 |
132 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.78191732 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.21486585 |
2 | MP0000685_abnormal_immune_system | 2.95276407 |
3 | MP0002396_abnormal_hematopoietic_system | 2.92494587 |
4 | MP0005058_abnormal_lysosome_morphology | 2.92145912 |
5 | MP0000465_gastrointestinal_hemorrhage | 2.63970570 |
6 | MP0005671_abnormal_response_to | 2.59008492 |
7 | MP0005464_abnormal_platelet_physiology | 2.51258033 |
8 | MP0006054_spinal_hemorrhage | 2.30773441 |
9 | MP0002419_abnormal_innate_immunity | 2.26653795 |
10 | MP0003724_increased_susceptibility_to | 2.22045404 |
11 | MP0001800_abnormal_humoral_immune | 2.21891637 |
12 | MP0002452_abnormal_antigen_presenting | 2.20209313 |
13 | MP0009785_altered_susceptibility_to | 2.18877516 |
14 | MP0005025_abnormal_response_to | 2.16946204 |
15 | MP0006082_CNS_inflammation | 2.15585453 |
16 | MP0004381_abnormal_hair_follicle | 2.12385707 |
17 | MP0005000_abnormal_immune_tolerance | 2.11447261 |
18 | MP0003436_decreased_susceptibility_to | 2.09222289 |
19 | MP0002420_abnormal_adaptive_immunity | 2.05861303 |
20 | MP0001819_abnormal_immune_cell | 2.03225178 |
21 | MP0010368_abnormal_lymphatic_system | 2.03196919 |
22 | MP0002723_abnormal_immune_serum | 2.02597038 |
23 | MP0002148_abnormal_hypersensitivity_rea | 1.99288380 |
24 | MP0005387_immune_system_phenotype | 1.94554974 |
25 | MP0001790_abnormal_immune_system | 1.94554974 |
26 | MP0009278_abnormal_bone_marrow | 1.90583071 |
27 | MP0003191_abnormal_cellular_cholesterol | 1.85611152 |
28 | MP0002398_abnormal_bone_marrow | 1.80096634 |
29 | MP0003763_abnormal_thymus_physiology | 1.77784228 |
30 | MP0010155_abnormal_intestine_physiology | 1.72636732 |
31 | MP0003300_gastrointestinal_ulcer | 1.72422551 |
32 | MP0000716_abnormal_immune_system | 1.72004111 |
33 | MP0001873_stomach_inflammation | 1.71337837 |
34 | MP0000689_abnormal_spleen_morphology | 1.71051700 |
35 | MP0002405_respiratory_system_inflammati | 1.69291896 |
36 | MP0001879_abnormal_lymphatic_vessel | 1.67424799 |
37 | MP0004808_abnormal_hematopoietic_stem | 1.65681686 |
38 | MP0003172_abnormal_lysosome_physiology | 1.61741499 |
39 | MP0002722_abnormal_immune_system | 1.57635170 |
40 | MP0005397_hematopoietic_system_phenotyp | 1.56442532 |
41 | MP0001545_abnormal_hematopoietic_system | 1.56442532 |
42 | MP0002429_abnormal_blood_cell | 1.55723674 |
43 | MP0005174_abnormal_tail_pigmentation | 1.53032464 |
44 | MP0009333_abnormal_splenocyte_physiolog | 1.51486549 |
45 | MP0001853_heart_inflammation | 1.49776875 |
46 | MP0001851_eye_inflammation | 1.47816048 |
47 | MP0005075_abnormal_melanosome_morpholog | 1.47525248 |
48 | MP0004858_abnormal_nervous_system | 1.45496857 |
49 | MP0004883_abnormal_blood_vessel | 1.43218095 |
50 | MP0004947_skin_inflammation | 1.40855160 |
51 | MP0003878_abnormal_ear_physiology | 1.40202734 |
52 | MP0005377_hearing/vestibular/ear_phenot | 1.40202734 |
53 | MP0000383_abnormal_hair_follicle | 1.38555817 |
54 | MP0004130_abnormal_muscle_cell | 1.38415916 |
55 | MP0003303_peritoneal_inflammation | 1.37195854 |
56 | MP0001533_abnormal_skeleton_physiology | 1.36055295 |
57 | MP0000920_abnormal_myelination | 1.35322961 |
58 | MP0002933_joint_inflammation | 1.35078656 |
59 | MP0001845_abnormal_inflammatory_respons | 1.33974313 |
60 | MP0000490_abnormal_crypts_of | 1.32283346 |
61 | MP0008260_abnormal_autophagy | 1.31974103 |
62 | MP0000343_altered_response_to | 1.28983762 |
63 | MP0009764_decreased_sensitivity_to | 1.28354792 |
64 | MP0009840_abnormal_foam_cell | 1.26738959 |
65 | MP0002254_reproductive_system_inflammat | 1.26737363 |
66 | MP0003943_abnormal_hepatobiliary_system | 1.25510907 |
67 | MP0002166_altered_tumor_susceptibility | 1.25049101 |
68 | MP0004147_increased_porphyrin_level | 1.24434773 |
69 | MP0005076_abnormal_cell_differentiation | 1.22949339 |
70 | MP0005164_abnormal_response_to | 1.20518240 |
71 | MP0010678_abnormal_skin_adnexa | 1.19980061 |
72 | MP0005451_abnormal_body_composition | 1.18491544 |
73 | MP0001663_abnormal_digestive_system | 1.18125928 |
74 | MP0003091_abnormal_cell_migration | 1.17467316 |
75 | MP0001915_intracranial_hemorrhage | 1.17383388 |
76 | MP0002138_abnormal_hepatobiliary_system | 1.16171673 |
77 | MP0008007_abnormal_cellular_replicative | 1.12006038 |
78 | MP0001849_ear_inflammation | 1.10153094 |
79 | MP0008469_abnormal_protein_level | 1.09784246 |
80 | MP0000703_abnormal_thymus_morphology | 1.08835408 |
81 | MP0003866_abnormal_defecation | 1.06156234 |
82 | MP0000604_amyloidosis | 1.02273165 |
83 | MP0003828_pulmonary_edema | 1.02182080 |
84 | MP0003566_abnormal_cell_adhesion | 1.01752874 |
85 | MP0002653_abnormal_ependyma_morphology | 1.01024867 |
86 | MP0005023_abnormal_wound_healing | 0.97213393 |
87 | MP0002277_abnormal_respiratory_mucosa | 0.96000125 |
88 | MP0000767_abnormal_smooth_muscle | 0.95595289 |
89 | MP0003453_abnormal_keratinocyte_physiol | 0.95408527 |
90 | MP0003950_abnormal_plasma_membrane | 0.92967436 |
91 | MP0005083_abnormal_biliary_tract | 0.92328442 |
92 | MP0000858_altered_metastatic_potential | 0.91459944 |
93 | MP0003075_altered_response_to | 0.86425731 |
94 | MP0000249_abnormal_blood_vessel | 0.86338254 |
95 | MP0004185_abnormal_adipocyte_glucose | 0.85956768 |
96 | MP0004272_abnormal_basement_membrane | 0.85557642 |
97 | MP0003448_altered_tumor_morphology | 0.85370909 |
98 | MP0003690_abnormal_glial_cell | 0.85047526 |
99 | MP0000015_abnormal_ear_pigmentation | 0.84357560 |
100 | MP0002998_abnormal_bone_remodeling | 0.84194807 |
101 | MP0003329_amyloid_beta_deposits | 0.83459541 |
102 | MP0005310_abnormal_salivary_gland | 0.82423864 |
103 | MP0004510_myositis | 0.80215688 |
104 | MP0003183_abnormal_peptide_metabolism | 0.79783919 |
105 | MP0002095_abnormal_skin_pigmentation | 0.79597155 |
106 | MP0003656_abnormal_erythrocyte_physiolo | 0.77794814 |
107 | MP0002019_abnormal_tumor_incidence | 0.77587626 |
108 | MP0005390_skeleton_phenotype | 0.75465180 |
109 | MP0008004_abnormal_stomach_pH | 0.74993852 |
110 | MP0005409_darkened_coat_color | 0.74778520 |
111 | MP0004264_abnormal_extraembryonic_tissu | 0.74709437 |
112 | MP0005666_abnormal_adipose_tissue | 0.73984935 |
113 | MP0002006_tumorigenesis | 0.73711911 |
114 | MP0005381_digestive/alimentary_phenotyp | 0.73690596 |
115 | MP0003279_aneurysm | 0.73178118 |
116 | MP0002132_abnormal_respiratory_system | 0.72477555 |
117 | MP0005670_abnormal_white_adipose | 0.72203097 |
118 | MP0000477_abnormal_intestine_morphology | 0.71985492 |
119 | MP0003638_abnormal_response/metabolism_ | 0.71896131 |
120 | MP0001958_emphysema | 0.68688276 |
121 | MP0004782_abnormal_surfactant_physiolog | 0.68396458 |
122 | MP0003077_abnormal_cell_cycle | 0.68394290 |
123 | MP0005167_abnormal_blood-brain_barrier | 0.67945990 |
124 | MP0009763_increased_sensitivity_to | 0.67651054 |
125 | MP0001614_abnormal_blood_vessel | 0.66992628 |
126 | MP0001216_abnormal_epidermal_layer | 0.66675428 |
127 | MP0009115_abnormal_fat_cell | 0.64119074 |
128 | MP0003795_abnormal_bone_structure | 0.62905303 |
129 | MP0008961_abnormal_basal_metabolism | 0.61343174 |
130 | MP0005166_decreased_susceptibility_to | 0.60370168 |
131 | MP0000371_diluted_coat_color | 0.59750168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 4.73983702 |
2 | Recurrent bacterial skin infections (HP:0005406) | 4.43850330 |
3 | Thrombocytosis (HP:0001894) | 4.18576812 |
4 | IgM deficiency (HP:0002850) | 4.12618787 |
5 | Systemic lupus erythematosus (HP:0002725) | 4.11888156 |
6 | Vacuolated lymphocytes (HP:0001922) | 4.06398861 |
7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.92957332 |
8 | Optic neuritis (HP:0100653) | 3.89951407 |
9 | Retrobulbar optic neuritis (HP:0100654) | 3.89951407 |
10 | Stomatitis (HP:0010280) | 3.88448480 |
11 | Spontaneous hematomas (HP:0007420) | 3.77354667 |
12 | Hematochezia (HP:0002573) | 3.67552938 |
13 | Abnormality of macrophages (HP:0004311) | 3.66177641 |
14 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.63595620 |
15 | Increased cerebral lipofuscin (HP:0011813) | 3.59133113 |
16 | Myositis (HP:0100614) | 3.53046002 |
17 | Chronic otitis media (HP:0000389) | 3.46932931 |
18 | Petechiae (HP:0000967) | 3.45951010 |
19 | Glomerulonephritis (HP:0000099) | 3.42387827 |
20 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.30264960 |
21 | Cellulitis (HP:0100658) | 3.22504023 |
22 | Mediastinal lymphadenopathy (HP:0100721) | 3.17529595 |
23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.16827024 |
24 | Eczematoid dermatitis (HP:0000976) | 3.15386893 |
25 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.14432697 |
26 | Interstitial pulmonary disease (HP:0006530) | 3.07788935 |
27 | Recurrent skin infections (HP:0001581) | 3.01903534 |
28 | Increased IgE level (HP:0003212) | 3.00333151 |
29 | T lymphocytopenia (HP:0005403) | 2.96709801 |
30 | Colitis (HP:0002583) | 2.90449451 |
31 | Abnormality of T cell number (HP:0011839) | 2.82389170 |
32 | Prolonged bleeding time (HP:0003010) | 2.81434054 |
33 | Inflammation of the large intestine (HP:0002037) | 2.78797051 |
34 | Keratoconjunctivitis sicca (HP:0001097) | 2.77575265 |
35 | Spondylolisthesis (HP:0003302) | 2.77365322 |
36 | Pustule (HP:0200039) | 2.70673176 |
37 | Hepatosplenomegaly (HP:0001433) | 2.67088967 |
38 | Gastrointestinal inflammation (HP:0004386) | 2.65194837 |
39 | Agammaglobulinemia (HP:0004432) | 2.60215566 |
40 | Dysostosis multiplex (HP:0000943) | 2.59987227 |
41 | Keratoconjunctivitis (HP:0001096) | 2.59207579 |
42 | Pulmonary infiltrates (HP:0002113) | 2.51966123 |
43 | Axonal loss (HP:0003447) | 2.51179706 |
44 | Recurrent viral infections (HP:0004429) | 2.50983926 |
45 | Loss of speech (HP:0002371) | 2.50631389 |
46 | Aplastic anemia (HP:0001915) | 2.50463002 |
47 | Encephalitis (HP:0002383) | 2.50284814 |
48 | Gastrointestinal stroma tumor (HP:0100723) | 2.48940950 |
49 | Panhypogammaglobulinemia (HP:0003139) | 2.47926082 |
50 | Abnormality of B cell number (HP:0010975) | 2.47545150 |
51 | B lymphocytopenia (HP:0010976) | 2.47545150 |
52 | Recurrent bronchitis (HP:0002837) | 2.47296193 |
53 | Epistaxis (HP:0000421) | 2.46305397 |
54 | Osteomyelitis (HP:0002754) | 2.45201334 |
55 | Gingivitis (HP:0000230) | 2.44823658 |
56 | Amyloidosis (HP:0011034) | 2.41503247 |
57 | Gastrointestinal infarctions (HP:0005244) | 2.40728171 |
58 | Arterial tortuosity (HP:0005116) | 2.35273539 |
59 | Recurrent fungal infections (HP:0002841) | 2.35249316 |
60 | Hemoptysis (HP:0002105) | 2.33677586 |
61 | Patchy hypopigmentation of hair (HP:0011365) | 2.32368221 |
62 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.32216566 |
63 | Recurrent cutaneous fungal infections (HP:0011370) | 2.32216566 |
64 | Progressive neurologic deterioration (HP:0002344) | 2.31601893 |
65 | Agnosia (HP:0010524) | 2.29413790 |
66 | Abnormal platelet function (HP:0011869) | 2.28571411 |
67 | Impaired platelet aggregation (HP:0003540) | 2.28571411 |
68 | White forelock (HP:0002211) | 2.28178645 |
69 | Diplopia (HP:0000651) | 2.27623723 |
70 | Abnormality of binocular vision (HP:0011514) | 2.27623723 |
71 | Abnormality of the nasal mucosa (HP:0000433) | 2.26174249 |
72 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.22447301 |
73 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.22447301 |
74 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.22447301 |
75 | Hemiplegia (HP:0002301) | 2.22063046 |
76 | Meningitis (HP:0001287) | 2.21272555 |
77 | Abnormality of T cell physiology (HP:0011840) | 2.20987365 |
78 | Polygenic inheritance (HP:0010982) | 2.18875762 |
79 | Orchitis (HP:0100796) | 2.18646964 |
80 | Thyroiditis (HP:0100646) | 2.18576394 |
81 | Reticulocytopenia (HP:0001896) | 2.18375681 |
82 | Purpura (HP:0000979) | 2.15084193 |
83 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.13639502 |
84 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.13639502 |
85 | Abnormality of glycolipid metabolism (HP:0010969) | 2.13639502 |
86 | Leukocytosis (HP:0001974) | 2.12125153 |
87 | Disinhibition (HP:0000734) | 2.11463973 |
88 | Autoimmune thrombocytopenia (HP:0001973) | 2.09118503 |
89 | Spinal cord lesions (HP:0100561) | 2.07709974 |
90 | Syringomyelia (HP:0003396) | 2.07709974 |
91 | Lymphopenia (HP:0001888) | 2.06716977 |
92 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.06115364 |
93 | Vascular tortuosity (HP:0004948) | 2.04810079 |
94 | Obstructive lung disease (HP:0006536) | 2.03226666 |
95 | Chronic obstructive pulmonary disease (HP:0006510) | 2.03226666 |
96 | Osteolytic defects of the hand bones (HP:0009699) | 2.02907606 |
97 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.02907606 |
98 | Chronic diarrhea (HP:0002028) | 2.02003034 |
99 | Vasculitis (HP:0002633) | 2.01763971 |
100 | Recurrent pneumonia (HP:0006532) | 2.01615006 |
101 | Abnormality of T cells (HP:0002843) | 1.98344125 |
102 | Hypochromic anemia (HP:0001931) | 1.97928677 |
103 | Thick nail (HP:0001805) | 1.97875429 |
104 | Gingival bleeding (HP:0000225) | 1.97229716 |
105 | Abnormality of eosinophils (HP:0001879) | 1.95024471 |
106 | Nephritis (HP:0000123) | 1.94958721 |
107 | Neurofibrillary tangles (HP:0002185) | 1.94655923 |
108 | Obstructive sleep apnea (HP:0002870) | 1.93832339 |
109 | Broad face (HP:0000283) | 1.93296564 |
110 | Global brain atrophy (HP:0002283) | 1.92641889 |
111 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.92595917 |
112 | Episodic fever (HP:0001954) | 1.92305361 |
113 | Type 2 muscle fiber atrophy (HP:0003554) | 1.91713758 |
114 | Pulmonary embolism (HP:0002204) | 1.91384362 |
115 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.91258831 |
116 | Abnormal platelet volume (HP:0011876) | 1.90981350 |
117 | Hypoproteinemia (HP:0003075) | 1.89336030 |
118 | Hemorrhage of the eye (HP:0011885) | 1.88631889 |
119 | Muscle fiber atrophy (HP:0100295) | 1.86492537 |
120 | Chest pain (HP:0100749) | 1.86049978 |
121 | Skin ulcer (HP:0200042) | 1.85412928 |
122 | Erythema (HP:0010783) | 1.85265362 |
123 | Acute myeloid leukemia (HP:0004808) | 1.83945108 |
124 | Mucopolysacchariduria (HP:0008155) | 1.83551521 |
125 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.83551521 |
126 | Stomach cancer (HP:0012126) | 1.83144200 |
127 | Eosinophilia (HP:0001880) | 1.81591150 |
128 | Increased serum ferritin (HP:0003281) | 1.78345981 |
129 | Milia (HP:0001056) | 1.77251486 |
130 | Acne (HP:0001061) | 1.77174276 |
131 | IgG deficiency (HP:0004315) | 1.76953605 |
132 | Clumsiness (HP:0002312) | 1.76852131 |
133 | Abnormality of the fingertips (HP:0001211) | 1.76292214 |
134 | Polycythemia (HP:0001901) | 1.76157897 |
135 | Parakeratosis (HP:0001036) | 1.76079695 |
136 | Lymphoma (HP:0002665) | 1.75907166 |
137 | Amaurosis fugax (HP:0100576) | 1.75459862 |
138 | Albinism (HP:0001022) | 1.75107656 |
139 | Stridor (HP:0010307) | 1.74537908 |
140 | Complement deficiency (HP:0004431) | 1.74318753 |
141 | Granulocytopenia (HP:0001913) | 1.73719925 |
142 | Restrictive lung disease (HP:0002091) | 1.73185901 |
143 | Recurrent lower respiratory tract infections (HP:0002783) | 1.71967755 |
144 | Urticaria (HP:0001025) | 1.71726204 |
145 | Abnormality of the pleura (HP:0002103) | 1.70865405 |
146 | Sepsis (HP:0100806) | 1.70830218 |
147 | Abnormality of the pericardium (HP:0001697) | 1.69379231 |
148 | Anorexia (HP:0002039) | 1.69030610 |
149 | Cheilitis (HP:0100825) | 1.67005509 |
150 | Acrocyanosis (HP:0001063) | 1.64287723 |
151 | Onion bulb formation (HP:0003383) | 1.64286360 |
152 | Arterial thrombosis (HP:0004420) | 1.63617795 |
153 | Vertigo (HP:0002321) | 1.62721766 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TGFBR2 | 4.11876901 |
2 | MAP4K1 | 3.50131705 |
3 | KIT | 3.01220821 |
4 | RIPK4 | 2.93363978 |
5 | TIE1 | 2.84635223 |
6 | EPHB1 | 2.72696099 |
7 | STK10 | 2.72388247 |
8 | CSF1R | 2.55838133 |
9 | KDR | 2.35207517 |
10 | TGFBR1 | 2.31659804 |
11 | BTK | 2.25539469 |
12 | EEF2K | 2.23501069 |
13 | MATK | 2.17031606 |
14 | PRPF4B | 2.11046835 |
15 | CLK1 | 1.99782208 |
16 | SIK2 | 1.99377548 |
17 | JAK3 | 1.99366542 |
18 | ZAP70 | 1.83334899 |
19 | IRAK4 | 1.82600820 |
20 | MAP2K3 | 1.81762442 |
21 | TYK2 | 1.75939221 |
22 | SIK1 | 1.75647229 |
23 | MAPKAPK5 | 1.68168745 |
24 | TAOK1 | 1.67984431 |
25 | TBK1 | 1.67402391 |
26 | LRRK2 | 1.63392669 |
27 | TNK2 | 1.61998642 |
28 | RIPK1 | 1.59624884 |
29 | MST4 | 1.59405430 |
30 | ERN1 | 1.56140556 |
31 | FLT3 | 1.54815679 |
32 | BLK | 1.54185907 |
33 | TEC | 1.52499799 |
34 | PAK4 | 1.50393046 |
35 | TYRO3 | 1.45049366 |
36 | MAP3K14 | 1.33551473 |
37 | ITK | 1.31941369 |
38 | PRKD2 | 1.31481359 |
39 | MARK2 | 1.29938459 |
40 | CDC42BPA | 1.27119849 |
41 | IRAK3 | 1.25542218 |
42 | SIK3 | 1.22129544 |
43 | TRPM7 | 1.21038715 |
44 | CDK12 | 1.18430938 |
45 | CSK | 1.17672926 |
46 | LCK | 1.17314112 |
47 | CDK8 | 1.15968664 |
48 | TXK | 1.14683405 |
49 | RPS6KB2 | 1.14192329 |
50 | IKBKE | 1.13489121 |
51 | IKBKB | 1.10707582 |
52 | SYK | 1.08225530 |
53 | EPHA3 | 1.03512111 |
54 | LYN | 1.03497267 |
55 | MAP3K1 | 0.98584444 |
56 | ICK | 0.96774691 |
57 | HCK | 0.96546086 |
58 | EPHA2 | 0.91103979 |
59 | MARK3 | 0.90936654 |
60 | STK39 | 0.90582538 |
61 | MAPK15 | 0.90232186 |
62 | MAP3K8 | 0.88219949 |
63 | PKN2 | 0.88142342 |
64 | FGFR4 | 0.87339435 |
65 | CAMKK1 | 0.86040005 |
66 | PTK6 | 0.85730747 |
67 | EPHB2 | 0.85726998 |
68 | MAP3K7 | 0.85443583 |
69 | MET | 0.84767657 |
70 | MAP3K6 | 0.83596862 |
71 | MAPKAPK3 | 0.82906964 |
72 | MOS | 0.79096821 |
73 | PDGFRB | 0.77949539 |
74 | YES1 | 0.77795599 |
75 | RET | 0.77219007 |
76 | PTK2B | 0.76337865 |
77 | GRK6 | 0.74239038 |
78 | STK38 | 0.73639560 |
79 | MKNK1 | 0.73464985 |
80 | IRAK1 | 0.72350639 |
81 | NLK | 0.70981507 |
82 | HIPK2 | 0.70476000 |
83 | MAP3K13 | 0.70137783 |
84 | PDPK1 | 0.70080880 |
85 | NEK9 | 0.67885476 |
86 | KSR2 | 0.66345257 |
87 | PDK1 | 0.66040691 |
88 | FGR | 0.65156053 |
89 | PRKG2 | 0.64819355 |
90 | TRIB3 | 0.62252584 |
91 | CAMKK2 | 0.61064268 |
92 | MAP2K2 | 0.60513952 |
93 | MAPKAPK2 | 0.60458016 |
94 | JAK1 | 0.60143984 |
95 | MAP3K3 | 0.59584159 |
96 | RPS6KA6 | 0.59497053 |
97 | MAP3K10 | 0.59040779 |
98 | WEE1 | 0.58874598 |
99 | ADRBK2 | 0.58074170 |
100 | RPS6KA4 | 0.57742100 |
101 | TAOK2 | 0.57190281 |
102 | FYN | 0.56063650 |
103 | CDK7 | 0.55374397 |
104 | OXSR1 | 0.54245680 |
105 | RPS6KA2 | 0.53393792 |
106 | CHUK | 0.52810234 |
107 | TAOK3 | 0.52502129 |
108 | BMX | 0.52454040 |
109 | MAPK4 | 0.52332287 |
110 | RPS6KL1 | 0.51111822 |
111 | RPS6KC1 | 0.51111822 |
112 | SGK3 | 0.50413353 |
113 | MAP3K11 | 0.50062963 |
114 | FES | 0.50047515 |
115 | NME2 | 0.49573510 |
116 | BMPR1B | 0.48944668 |
117 | BUB1 | 0.48865915 |
118 | DYRK1B | 0.48771807 |
119 | SMG1 | 0.48453223 |
120 | MAP2K6 | 0.48227548 |
121 | CSNK1G3 | 0.45615636 |
122 | SGK2 | 0.44727990 |
123 | VRK1 | 0.43674342 |
124 | TESK2 | 0.43536560 |
125 | MAPK12 | 0.43440782 |
126 | CSNK1A1L | 0.43186585 |
127 | PIK3CG | 0.42872796 |
128 | PIM1 | 0.42857288 |
129 | PAK2 | 0.42855455 |
130 | BRD4 | 0.42832313 |
131 | CDK9 | 0.41968972 |
132 | IGF1R | 0.40825489 |
133 | PRKCQ | 0.40771170 |
134 | PRKCH | 0.40147004 |
135 | ILK | 0.40056387 |
136 | DAPK2 | 0.39919022 |
137 | MAP3K2 | 0.39231814 |
138 | PIM2 | 0.39129690 |
139 | MELK | 0.38539733 |
140 | TSSK6 | 0.38530382 |
141 | FGFR3 | 0.38527425 |
142 | CAMK1D | 0.37309627 |
143 | MAPK7 | 0.37174785 |
144 | CSNK1G1 | 0.36880279 |
145 | JAK2 | 0.36518589 |
146 | RPS6KA5 | 0.36403780 |
147 | FGFR2 | 0.36355617 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Other glycan degradation_Homo sapiens_hsa00511 | 2.84490828 |
2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.51095883 |
3 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.45222782 |
4 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.22694011 |
5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.10990669 |
6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.08558831 |
7 | Lysosome_Homo sapiens_hsa04142 | 1.92171185 |
8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.80026758 |
9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.79529509 |
10 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.79038419 |
11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.76907016 |
12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.72695983 |
13 | Ribosome_Homo sapiens_hsa03010 | 1.67759509 |
14 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.66221835 |
15 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.63538255 |
16 | DNA replication_Homo sapiens_hsa03030 | 1.61670639 |
17 | Pertussis_Homo sapiens_hsa05133 | 1.59217727 |
18 | Base excision repair_Homo sapiens_hsa03410 | 1.52223571 |
19 | Malaria_Homo sapiens_hsa05144 | 1.44874104 |
20 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.43254131 |
21 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.42258929 |
22 | Shigellosis_Homo sapiens_hsa05131 | 1.41637818 |
23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.41268797 |
24 | Measles_Homo sapiens_hsa05162 | 1.40840554 |
25 | Mismatch repair_Homo sapiens_hsa03430 | 1.40510889 |
26 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.39397006 |
27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.36206975 |
28 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.33194098 |
29 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.32578551 |
30 | Platelet activation_Homo sapiens_hsa04611 | 1.31941463 |
31 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.31898209 |
32 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.29775443 |
33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.29203775 |
34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.28317141 |
35 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.28217818 |
36 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.22175585 |
37 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.18674346 |
38 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.18559262 |
39 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.17496050 |
40 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.14438929 |
41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.14245587 |
42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.11937544 |
43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.10852513 |
44 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.10430328 |
45 | Legionellosis_Homo sapiens_hsa05134 | 1.09827707 |
46 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.09283073 |
47 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.08709438 |
48 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.08073304 |
49 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.07703281 |
50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.07591668 |
51 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.05996093 |
52 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.05092844 |
53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.04241884 |
54 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.03134895 |
55 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.02059843 |
56 | Apoptosis_Homo sapiens_hsa04210 | 0.99632877 |
57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.96569635 |
58 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.95941955 |
59 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.95820882 |
60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95125260 |
61 | Tuberculosis_Homo sapiens_hsa05152 | 0.94142220 |
62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.93929988 |
63 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.90768267 |
64 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.90653099 |
65 | Salmonella infection_Homo sapiens_hsa05132 | 0.89531890 |
66 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89383503 |
67 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.88867524 |
68 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.87325866 |
69 | Hepatitis B_Homo sapiens_hsa05161 | 0.86138341 |
70 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.85860502 |
71 | Endometrial cancer_Homo sapiens_hsa05213 | 0.85387666 |
72 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.82035971 |
73 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.80850870 |
74 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.80757100 |
75 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.80696280 |
76 | Amoebiasis_Homo sapiens_hsa05146 | 0.79849664 |
77 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.79525137 |
78 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79031750 |
79 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77606596 |
80 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.77594495 |
81 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.76865415 |
82 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.76605184 |
83 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.75793880 |
84 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.75480525 |
85 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.73727459 |
86 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.73188175 |
87 | Influenza A_Homo sapiens_hsa05164 | 0.72359749 |
88 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70527626 |
89 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.69845443 |
90 | Hepatitis C_Homo sapiens_hsa05160 | 0.68651702 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.67873308 |
92 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67173269 |
93 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.66625197 |
94 | Insulin resistance_Homo sapiens_hsa04931 | 0.64336905 |
95 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.63999411 |
96 | Histidine metabolism_Homo sapiens_hsa00340 | 0.63691999 |
97 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.62914568 |
98 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.61712414 |
99 | Pathways in cancer_Homo sapiens_hsa05200 | 0.61534603 |
100 | Bladder cancer_Homo sapiens_hsa05219 | 0.61100388 |
101 | Axon guidance_Homo sapiens_hsa04360 | 0.60829485 |
102 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60627581 |
103 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60559560 |
104 | HTLV-I infection_Homo sapiens_hsa05166 | 0.60360244 |
105 | Cell cycle_Homo sapiens_hsa04110 | 0.60212349 |
106 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.60031653 |
107 | Homologous recombination_Homo sapiens_hsa03440 | 0.59986309 |
108 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.59501525 |
109 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.59483852 |
110 | Endocytosis_Homo sapiens_hsa04144 | 0.59346076 |
111 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.56868979 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.56590525 |
113 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.56403783 |
114 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.56175286 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.55813014 |
116 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55464684 |
117 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.55387303 |
118 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.54685102 |
119 | Prostate cancer_Homo sapiens_hsa05215 | 0.54612278 |
120 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.53626222 |
121 | Phagosome_Homo sapiens_hsa04145 | 0.53500751 |
122 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53221906 |
123 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.52449876 |
124 | Protein export_Homo sapiens_hsa03060 | 0.51276849 |
125 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.50402607 |
126 | Thyroid cancer_Homo sapiens_hsa05216 | 0.50337496 |
127 | Focal adhesion_Homo sapiens_hsa04510 | 0.48933401 |
128 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.48791738 |
129 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.48360780 |
130 | Spliceosome_Homo sapiens_hsa03040 | 0.44834722 |
131 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.43552182 |
132 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.43358983 |
133 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.42512931 |
134 | Allograft rejection_Homo sapiens_hsa05330 | 0.41838862 |