

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 7.01033971 |
| 2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 6.94891385 |
| 3 | synaptic vesicle exocytosis (GO:0016079) | 5.93691970 |
| 4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.78478980 |
| 5 | glutamate secretion (GO:0014047) | 5.55062603 |
| 6 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.51537871 |
| 7 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.50519981 |
| 8 | locomotory exploration behavior (GO:0035641) | 4.87018152 |
| 9 | regulation of ARF protein signal transduction (GO:0032012) | 4.84414689 |
| 10 | regulation of synaptic vesicle transport (GO:1902803) | 4.62145563 |
| 11 | neurotransmitter secretion (GO:0007269) | 4.58700568 |
| 12 | L-amino acid import (GO:0043092) | 4.47969648 |
| 13 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.41004103 |
| 14 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.40996781 |
| 15 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.32405568 |
| 16 | vocalization behavior (GO:0071625) | 4.31538333 |
| 17 | exploration behavior (GO:0035640) | 4.26289247 |
| 18 | cellular potassium ion homeostasis (GO:0030007) | 4.20760580 |
| 19 | cerebellar granule cell differentiation (GO:0021707) | 4.19131415 |
| 20 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.06707869 |
| 21 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.03407270 |
| 22 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.01541312 |
| 23 | sodium ion export (GO:0071436) | 3.99058385 |
| 24 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.93762506 |
| 25 | positive regulation of synapse maturation (GO:0090129) | 3.87311417 |
| 26 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.86845111 |
| 27 | dendritic spine morphogenesis (GO:0060997) | 3.82197670 |
| 28 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.77196917 |
| 29 | amino acid import (GO:0043090) | 3.63009788 |
| 30 | positive regulation of membrane potential (GO:0045838) | 3.60761880 |
| 31 | synaptic transmission, glutamatergic (GO:0035249) | 3.60597988 |
| 32 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.56886771 |
| 33 | neuronal ion channel clustering (GO:0045161) | 3.56371696 |
| 34 | neurotransmitter transport (GO:0006836) | 3.53006423 |
| 35 | protein localization to synapse (GO:0035418) | 3.48227690 |
| 36 | regulation of synaptic plasticity (GO:0048167) | 3.44414652 |
| 37 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.40887981 |
| 38 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.40365122 |
| 39 | regulation of neurotransmitter levels (GO:0001505) | 3.40295260 |
| 40 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.38186432 |
| 41 | neuromuscular process controlling balance (GO:0050885) | 3.36883173 |
| 42 | synaptic vesicle endocytosis (GO:0048488) | 3.34705297 |
| 43 | postsynaptic membrane organization (GO:0001941) | 3.33621339 |
| 44 | neuronal action potential propagation (GO:0019227) | 3.32708684 |
| 45 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.32558371 |
| 46 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.30410069 |
| 47 | regulation of neurotransmitter secretion (GO:0046928) | 3.30145140 |
| 48 | regulation of synapse maturation (GO:0090128) | 3.27800359 |
| 49 | positive regulation of Rap GTPase activity (GO:0032854) | 3.25975227 |
| 50 | glutamate receptor signaling pathway (GO:0007215) | 3.23507891 |
| 51 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.19883690 |
| 52 | positive regulation of dendritic spine development (GO:0060999) | 3.18707878 |
| 53 | regulation of vesicle fusion (GO:0031338) | 3.17968008 |
| 54 | regulation of synapse structural plasticity (GO:0051823) | 3.16433365 |
| 55 | neuron-neuron synaptic transmission (GO:0007270) | 3.11077038 |
| 56 | potassium ion import (GO:0010107) | 3.10797384 |
| 57 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.06090843 |
| 58 | regulation of postsynaptic membrane potential (GO:0060078) | 3.05827544 |
| 59 | potassium ion homeostasis (GO:0055075) | 3.03998530 |
| 60 | long-term memory (GO:0007616) | 3.03929925 |
| 61 | axon ensheathment in central nervous system (GO:0032291) | 3.03131864 |
| 62 | central nervous system myelination (GO:0022010) | 3.03131864 |
| 63 | gamma-aminobutyric acid transport (GO:0015812) | 3.02055558 |
| 64 | regulation of Rap GTPase activity (GO:0032317) | 2.97533195 |
| 65 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.94914935 |
| 66 | membrane depolarization during action potential (GO:0086010) | 2.94724906 |
| 67 | regulation of neurotransmitter transport (GO:0051588) | 2.93704683 |
| 68 | cell differentiation in hindbrain (GO:0021533) | 2.91723720 |
| 69 | mechanosensory behavior (GO:0007638) | 2.89401291 |
| 70 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.88093344 |
| 71 | regulation of ARF GTPase activity (GO:0032312) | 2.84445890 |
| 72 | neuron cell-cell adhesion (GO:0007158) | 2.84168516 |
| 73 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.82667327 |
| 74 | activation of protein kinase A activity (GO:0034199) | 2.81803007 |
| 75 | regulation of exocytosis (GO:0017157) | 2.80809458 |
| 76 | dendritic spine organization (GO:0097061) | 2.80380635 |
| 77 | layer formation in cerebral cortex (GO:0021819) | 2.80324486 |
| 78 | auditory behavior (GO:0031223) | 2.80301958 |
| 79 | membrane depolarization (GO:0051899) | 2.79994952 |
| 80 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.77967009 |
| 81 | mannose metabolic process (GO:0006013) | 2.76213893 |
| 82 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.75444747 |
| 83 | phosphorelay signal transduction system (GO:0000160) | 2.75327123 |
| 84 | regulation of female receptivity (GO:0045924) | 2.74618608 |
| 85 | long-term synaptic potentiation (GO:0060291) | 2.73994485 |
| 86 | regulation of synaptic transmission (GO:0050804) | 2.73097678 |
| 87 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.70537189 |
| 88 | positive regulation of neurotransmitter transport (GO:0051590) | 2.69429239 |
| 89 | visual learning (GO:0008542) | 2.65088554 |
| 90 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.59550702 |
| 91 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.58777902 |
| 92 | transmission of nerve impulse (GO:0019226) | 2.58677073 |
| 93 | visual behavior (GO:0007632) | 2.57976876 |
| 94 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.57538482 |
| 95 | signal complex assembly (GO:0007172) | 2.56683630 |
| 96 | cell communication by electrical coupling (GO:0010644) | 2.55756615 |
| 97 | positive thymic T cell selection (GO:0045059) | 2.54136350 |
| 98 | regulation of dendritic spine development (GO:0060998) | 2.53652860 |
| 99 | dopamine receptor signaling pathway (GO:0007212) | 2.53086715 |
| 100 | learning (GO:0007612) | 2.52909363 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.30353470 |
| 2 | DROSHA_22980978_ChIP-Seq_HELA_Human | 3.88127605 |
| 3 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 3.24358387 |
| 4 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.87419129 |
| 5 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.74143316 |
| 6 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.72019414 |
| 7 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.56989953 |
| 8 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.56892466 |
| 9 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.45898891 |
| 10 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.44437807 |
| 11 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.27117740 |
| 12 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.19357259 |
| 13 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.17219249 |
| 14 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.14479696 |
| 15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.11590864 |
| 16 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.11138954 |
| 17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.08654130 |
| 18 | KDM2B_26808549_Chip-Seq_K562_Human | 2.01910873 |
| 19 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.01335606 |
| 20 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.99267594 |
| 21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.97830805 |
| 22 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.97772704 |
| 23 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.97551697 |
| 24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.96380729 |
| 25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.93235351 |
| 26 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.86232836 |
| 27 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.85103877 |
| 28 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.84307864 |
| 29 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.81936619 |
| 30 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.81839285 |
| 31 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.80170986 |
| 32 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.78314800 |
| 33 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.76363787 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.71858888 |
| 35 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.67748601 |
| 36 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.67748601 |
| 37 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.65691674 |
| 38 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.64573322 |
| 39 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.61779991 |
| 40 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.61679743 |
| 41 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.59976448 |
| 42 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.58377004 |
| 43 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.56726919 |
| 44 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.56015403 |
| 45 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.53194908 |
| 46 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.52947230 |
| 47 | MYC_22102868_ChIP-Seq_BL_Human | 1.49369507 |
| 48 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.48320247 |
| 49 | P68_20966046_ChIP-Seq_HELA_Human | 1.46557340 |
| 50 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.46219661 |
| 51 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.44822195 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.43679229 |
| 53 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.42774589 |
| 54 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.42406704 |
| 55 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.38486883 |
| 56 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.38387553 |
| 57 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.32067686 |
| 58 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.28981504 |
| 59 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.23120937 |
| 60 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.19123294 |
| 61 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.18508042 |
| 62 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.18168851 |
| 63 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.16274541 |
| 64 | UTX_26944678_Chip-Seq_JUKART_Human | 1.14764368 |
| 65 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.14622783 |
| 66 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.14087649 |
| 67 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.13433073 |
| 68 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11255278 |
| 69 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.10179471 |
| 70 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.09897892 |
| 71 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.09219419 |
| 72 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.09009239 |
| 73 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08728395 |
| 74 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.08518304 |
| 75 | SPI1_23127762_ChIP-Seq_K562_Human | 1.06281160 |
| 76 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.05402447 |
| 77 | KLF4_19829295_ChIP-Seq_ESCs_Human | 1.04997728 |
| 78 | MAF_26560356_Chip-Seq_TH1_Human | 1.03829071 |
| 79 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.02101596 |
| 80 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.00053903 |
| 81 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.99614760 |
| 82 | MAF_26560356_Chip-Seq_TH2_Human | 0.99592135 |
| 83 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.99459597 |
| 84 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.98547576 |
| 85 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.98519835 |
| 86 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.97591961 |
| 87 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.95318404 |
| 88 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.94678152 |
| 89 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.94565202 |
| 90 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.94547301 |
| 91 | AR_19668381_ChIP-Seq_PC3_Human | 0.93017932 |
| 92 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.92887388 |
| 93 | GATA1_19941826_ChIP-Seq_K562_Human | 0.92847250 |
| 94 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.91487485 |
| 95 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.90955865 |
| 96 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.90022407 |
| 97 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.86452246 |
| 98 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.85209014 |
| 99 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.85133189 |
| 100 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.84018656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 6.31492700 |
| 2 | MP0003880_abnormal_central_pattern | 4.45516587 |
| 3 | MP0003635_abnormal_synaptic_transmissio | 3.79762538 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.69147900 |
| 5 | MP0002064_seizures | 3.31039763 |
| 6 | MP0004270_analgesia | 3.19841991 |
| 7 | MP0002063_abnormal_learning/memory/cond | 3.05377166 |
| 8 | MP0009745_abnormal_behavioral_response | 2.98061499 |
| 9 | MP0001486_abnormal_startle_reflex | 2.81478427 |
| 10 | MP0002572_abnormal_emotion/affect_behav | 2.50568324 |
| 11 | MP0003172_abnormal_lysosome_physiology | 2.43328466 |
| 12 | MP0002272_abnormal_nervous_system | 2.42628937 |
| 13 | MP0009046_muscle_twitch | 2.41108516 |
| 14 | MP0008569_lethality_at_weaning | 2.38902116 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.38677452 |
| 16 | MP0001501_abnormal_sleep_pattern | 2.32056678 |
| 17 | MP0002734_abnormal_mechanical_nocicepti | 2.24985170 |
| 18 | MP0003787_abnormal_imprinting | 2.24796877 |
| 19 | MP0002735_abnormal_chemical_nociception | 2.22370461 |
| 20 | MP0003690_abnormal_glial_cell | 2.18145839 |
| 21 | MP0003329_amyloid_beta_deposits | 1.91774126 |
| 22 | MP0001970_abnormal_pain_threshold | 1.87740009 |
| 23 | MP0002822_catalepsy | 1.83469164 |
| 24 | MP0009278_abnormal_bone_marrow | 1.76525342 |
| 25 | MP0003879_abnormal_hair_cell | 1.71309555 |
| 26 | MP0002733_abnormal_thermal_nociception | 1.71174842 |
| 27 | MP0001986_abnormal_taste_sensitivity | 1.65029412 |
| 28 | MP0004742_abnormal_vestibular_system | 1.55082936 |
| 29 | MP0003183_abnormal_peptide_metabolism | 1.51418147 |
| 30 | MP0001502_abnormal_circadian_rhythm | 1.50493188 |
| 31 | MP0004811_abnormal_neuron_physiology | 1.47563823 |
| 32 | MP0002067_abnormal_sensory_capabilities | 1.44118871 |
| 33 | MP0004885_abnormal_endolymph | 1.37828644 |
| 34 | MP0003303_peritoneal_inflammation | 1.35121078 |
| 35 | MP0000920_abnormal_myelination | 1.35109086 |
| 36 | MP0003633_abnormal_nervous_system | 1.34230264 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.34005405 |
| 38 | MP0002557_abnormal_social/conspecific_i | 1.33417962 |
| 39 | MP0002066_abnormal_motor_capabilities/c | 1.30328963 |
| 40 | MP0001440_abnormal_grooming_behavior | 1.25504321 |
| 41 | MP0009780_abnormal_chondrocyte_physiolo | 1.25385253 |
| 42 | MP0005646_abnormal_pituitary_gland | 1.23584339 |
| 43 | MP0002736_abnormal_nociception_after | 1.22351779 |
| 44 | MP0004130_abnormal_muscle_cell | 1.21320578 |
| 45 | MP0002882_abnormal_neuron_morphology | 1.18952228 |
| 46 | MP0003631_nervous_system_phenotype | 1.16989050 |
| 47 | MP0000778_abnormal_nervous_system | 1.16553294 |
| 48 | MP0004924_abnormal_behavior | 1.15631844 |
| 49 | MP0005386_behavior/neurological_phenoty | 1.15631844 |
| 50 | MP0002653_abnormal_ependyma_morphology | 1.14151707 |
| 51 | MP0001485_abnormal_pinna_reflex | 1.07845954 |
| 52 | MP0000604_amyloidosis | 1.07444192 |
| 53 | MP0000569_abnormal_digit_pigmentation | 1.06571349 |
| 54 | MP0003436_decreased_susceptibility_to | 1.05938471 |
| 55 | MP0003075_altered_response_to | 1.02863351 |
| 56 | MP0001177_atelectasis | 1.02133159 |
| 57 | MP0001984_abnormal_olfaction | 1.01335742 |
| 58 | MP0000955_abnormal_spinal_cord | 1.00705187 |
| 59 | MP0003763_abnormal_thymus_physiology | 1.00549579 |
| 60 | MP0006276_abnormal_autonomic_nervous | 0.98855969 |
| 61 | MP0001963_abnormal_hearing_physiology | 0.98285366 |
| 62 | MP0002229_neurodegeneration | 0.97601164 |
| 63 | MP0003634_abnormal_glial_cell | 0.97360037 |
| 64 | MP0008874_decreased_physiological_sensi | 0.96966859 |
| 65 | MP0005535_abnormal_body_temperature | 0.96482898 |
| 66 | MP0005409_darkened_coat_color | 0.96082641 |
| 67 | MP0002152_abnormal_brain_morphology | 0.92061652 |
| 68 | MP0005397_hematopoietic_system_phenotyp | 0.88381042 |
| 69 | MP0001545_abnormal_hematopoietic_system | 0.88381042 |
| 70 | MP0003632_abnormal_nervous_system | 0.82629522 |
| 71 | MP0005645_abnormal_hypothalamus_physiol | 0.80848049 |
| 72 | MP0001835_abnormal_antigen_presentation | 0.79497148 |
| 73 | MP0004043_abnormal_pH_regulation | 0.75515234 |
| 74 | MP0001905_abnormal_dopamine_level | 0.75237517 |
| 75 | MP0002419_abnormal_innate_immunity | 0.75104527 |
| 76 | MP0001800_abnormal_humoral_immune | 0.73231077 |
| 77 | MP0008877_abnormal_DNA_methylation | 0.71627051 |
| 78 | MP0002420_abnormal_adaptive_immunity | 0.71064041 |
| 79 | MP0001765_abnormal_ion_homeostasis | 0.69516015 |
| 80 | MP0003122_maternal_imprinting | 0.69285752 |
| 81 | MP0005025_abnormal_response_to | 0.68955754 |
| 82 | MP0002184_abnormal_innervation | 0.68413552 |
| 83 | MP0001819_abnormal_immune_cell | 0.68375232 |
| 84 | MP0000015_abnormal_ear_pigmentation | 0.65906206 |
| 85 | MP0000566_synostosis | 0.64764553 |
| 86 | MP0005166_decreased_susceptibility_to | 0.63897772 |
| 87 | MP0000681_abnormal_thyroid_gland | 0.63829728 |
| 88 | MP0003045_fibrosis | 0.63663494 |
| 89 | MP0005000_abnormal_immune_tolerance | 0.62926257 |
| 90 | MP0002398_abnormal_bone_marrow | 0.61480284 |
| 91 | MP0002083_premature_death | 0.59386354 |
| 92 | MP0002069_abnormal_eating/drinking_beha | 0.59281261 |
| 93 | MP0004381_abnormal_hair_follicle | 0.58648032 |
| 94 | MP0002873_normal_phenotype | 0.57271660 |
| 95 | MP0003283_abnormal_digestive_organ | 0.56850216 |
| 96 | MP0000703_abnormal_thymus_morphology | 0.56308216 |
| 97 | MP0002169_no_abnormal_phenotype | 0.55847491 |
| 98 | MP0000716_abnormal_immune_system | 0.54828936 |
| 99 | MP0010769_abnormal_survival | 0.54079093 |
| 100 | MP0002638_abnormal_pupillary_reflex | 0.53219713 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 6.07110104 |
| 2 | Focal motor seizures (HP:0011153) | 5.48252540 |
| 3 | Papilledema (HP:0001085) | 4.83805318 |
| 4 | Obstructive sleep apnea (HP:0002870) | 4.72831148 |
| 5 | Focal seizures (HP:0007359) | 4.68210332 |
| 6 | Febrile seizures (HP:0002373) | 4.59984628 |
| 7 | Diplopia (HP:0000651) | 4.45794803 |
| 8 | Abnormality of binocular vision (HP:0011514) | 4.45794803 |
| 9 | Supranuclear gaze palsy (HP:0000605) | 4.36203130 |
| 10 | Epileptic encephalopathy (HP:0200134) | 4.32365912 |
| 11 | Ankle clonus (HP:0011448) | 4.23831815 |
| 12 | Hemiplegia (HP:0002301) | 4.01981910 |
| 13 | Visual hallucinations (HP:0002367) | 3.74230057 |
| 14 | Annular pancreas (HP:0001734) | 3.59036036 |
| 15 | Action tremor (HP:0002345) | 3.58179832 |
| 16 | Progressive cerebellar ataxia (HP:0002073) | 3.50877539 |
| 17 | Atonic seizures (HP:0010819) | 3.27409090 |
| 18 | Postural instability (HP:0002172) | 3.26684213 |
| 19 | Spastic gait (HP:0002064) | 3.24416151 |
| 20 | Neurofibrillary tangles (HP:0002185) | 3.09563197 |
| 21 | Panhypogammaglobulinemia (HP:0003139) | 2.98508337 |
| 22 | Hyperventilation (HP:0002883) | 2.96754452 |
| 23 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.96126689 |
| 24 | Abnormal eating behavior (HP:0100738) | 2.82762912 |
| 25 | Neuronal loss in central nervous system (HP:0002529) | 2.81148182 |
| 26 | Truncal ataxia (HP:0002078) | 2.78410813 |
| 27 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.71925091 |
| 28 | Absent/shortened dynein arms (HP:0200106) | 2.71925091 |
| 29 | Impaired smooth pursuit (HP:0007772) | 2.68904995 |
| 30 | Sleep apnea (HP:0010535) | 2.66157459 |
| 31 | Acute lymphatic leukemia (HP:0006721) | 2.64716526 |
| 32 | Tetraplegia (HP:0002445) | 2.64376147 |
| 33 | Torticollis (HP:0000473) | 2.60737099 |
| 34 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.58060874 |
| 35 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.58060874 |
| 36 | Generalized tonic-clonic seizures (HP:0002069) | 2.57660750 |
| 37 | Genetic anticipation (HP:0003743) | 2.56273476 |
| 38 | Absence seizures (HP:0002121) | 2.53950625 |
| 39 | Depression (HP:0000716) | 2.51295685 |
| 40 | Dysmetria (HP:0001310) | 2.49189364 |
| 41 | Agammaglobulinemia (HP:0004432) | 2.46769357 |
| 42 | Stereotypic behavior (HP:0000733) | 2.45876273 |
| 43 | Abnormal ciliary motility (HP:0012262) | 2.38800606 |
| 44 | Cerebral inclusion bodies (HP:0100314) | 2.36108118 |
| 45 | Peripheral hypomyelination (HP:0007182) | 2.35777011 |
| 46 | Dysdiadochokinesis (HP:0002075) | 2.34234532 |
| 47 | Dialeptic seizures (HP:0011146) | 2.30571450 |
| 48 | Mutism (HP:0002300) | 2.29852423 |
| 49 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.29587794 |
| 50 | Lower limb muscle weakness (HP:0007340) | 2.25644275 |
| 51 | Abnormality of the fingertips (HP:0001211) | 2.24208717 |
| 52 | Clonus (HP:0002169) | 2.22943291 |
| 53 | Intention tremor (HP:0002080) | 2.22158571 |
| 54 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.21743615 |
| 55 | Status epilepticus (HP:0002133) | 2.20878340 |
| 56 | Lower limb asymmetry (HP:0100559) | 2.20255134 |
| 57 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.16291023 |
| 58 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.16113050 |
| 59 | Urinary urgency (HP:0000012) | 2.15091766 |
| 60 | Poor eye contact (HP:0000817) | 2.14840549 |
| 61 | Dysmetric saccades (HP:0000641) | 2.14652046 |
| 62 | Slow saccadic eye movements (HP:0000514) | 2.11964995 |
| 63 | Spinal canal stenosis (HP:0003416) | 2.11172523 |
| 64 | Pointed chin (HP:0000307) | 2.11079987 |
| 65 | Bradykinesia (HP:0002067) | 2.09569443 |
| 66 | Ocular albinism (HP:0001107) | 2.08176732 |
| 67 | Nasal polyposis (HP:0100582) | 2.03204998 |
| 68 | Limb dystonia (HP:0002451) | 2.03143571 |
| 69 | Impaired vibratory sensation (HP:0002495) | 2.01752007 |
| 70 | Focal dystonia (HP:0004373) | 1.99234184 |
| 71 | Absent speech (HP:0001344) | 1.99224647 |
| 72 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.98366993 |
| 73 | Scanning speech (HP:0002168) | 1.96913313 |
| 74 | Hypoplasia of the thymus (HP:0000778) | 1.93617808 |
| 75 | Gaze-evoked nystagmus (HP:0000640) | 1.93166115 |
| 76 | Abnormality of saccadic eye movements (HP:0000570) | 1.92069583 |
| 77 | Apathy (HP:0000741) | 1.90443535 |
| 78 | Megalencephaly (HP:0001355) | 1.89935799 |
| 79 | Delusions (HP:0000746) | 1.87047915 |
| 80 | Abnormal social behavior (HP:0012433) | 1.84478064 |
| 81 | Impaired social interactions (HP:0000735) | 1.84478064 |
| 82 | Epileptiform EEG discharges (HP:0011182) | 1.84239756 |
| 83 | Hemiparesis (HP:0001269) | 1.83963911 |
| 84 | Rhinitis (HP:0012384) | 1.83742520 |
| 85 | Iris hypopigmentation (HP:0007730) | 1.83090640 |
| 86 | Chronic otitis media (HP:0000389) | 1.81889509 |
| 87 | Craniofacial dystonia (HP:0012179) | 1.79291353 |
| 88 | Meningitis (HP:0001287) | 1.76960834 |
| 89 | Bowel incontinence (HP:0002607) | 1.76639657 |
| 90 | Bronchomalacia (HP:0002780) | 1.76399279 |
| 91 | Rigidity (HP:0002063) | 1.75823877 |
| 92 | Broad face (HP:0000283) | 1.75279944 |
| 93 | B lymphocytopenia (HP:0010976) | 1.75059338 |
| 94 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.74255171 |
| 95 | Intellectual disability, severe (HP:0010864) | 1.74123558 |
| 96 | Recurrent fungal infections (HP:0002841) | 1.73001508 |
| 97 | Polygenic inheritance (HP:0010982) | 1.72461872 |
| 98 | Abnormality of the lower motor neuron (HP:0002366) | 1.72120577 |
| 99 | Rapidly progressive (HP:0003678) | 1.69093780 |
| 100 | Diminished motivation (HP:0000745) | 1.68501935 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 3.81466691 |
| 2 | DAPK2 | 3.28299639 |
| 3 | RIPK4 | 3.20553597 |
| 4 | NTRK3 | 3.18918281 |
| 5 | PAK6 | 2.99101460 |
| 6 | PRPF4B | 2.84754307 |
| 7 | TNK2 | 2.50684344 |
| 8 | CAMKK1 | 2.50201021 |
| 9 | MARK1 | 2.38655093 |
| 10 | UHMK1 | 2.30997269 |
| 11 | NTRK2 | 2.11934870 |
| 12 | SIK2 | 2.06277924 |
| 13 | PRKD3 | 2.04091018 |
| 14 | FES | 2.01373858 |
| 15 | MARK2 | 1.99611697 |
| 16 | MAPK15 | 1.74074227 |
| 17 | TRIB3 | 1.52018268 |
| 18 | MAP3K13 | 1.48822917 |
| 19 | MINK1 | 1.44775804 |
| 20 | MAPK12 | 1.42612434 |
| 21 | KIT | 1.41743149 |
| 22 | MAP4K1 | 1.41549241 |
| 23 | CDK19 | 1.33652449 |
| 24 | PRKCH | 1.26685251 |
| 25 | RIPK1 | 1.26348051 |
| 26 | SGK223 | 1.23913344 |
| 27 | SGK494 | 1.23913344 |
| 28 | CAMK1 | 1.23260947 |
| 29 | CDK5 | 1.18635457 |
| 30 | MAPK13 | 1.17074572 |
| 31 | STK11 | 1.14328531 |
| 32 | GRK5 | 1.12741902 |
| 33 | CDK12 | 1.11409265 |
| 34 | SGK2 | 1.09308958 |
| 35 | MAP3K7 | 1.08489480 |
| 36 | KSR2 | 1.06191962 |
| 37 | PDK1 | 1.01408754 |
| 38 | SYK | 0.99943475 |
| 39 | BTK | 0.97119292 |
| 40 | SGK3 | 0.91876210 |
| 41 | NTRK1 | 0.91620693 |
| 42 | DAPK1 | 0.91404939 |
| 43 | TYRO3 | 0.90851920 |
| 44 | MAP3K4 | 0.86713559 |
| 45 | CAMK4 | 0.86082724 |
| 46 | DYRK1A | 0.85562652 |
| 47 | HIPK2 | 0.85509799 |
| 48 | RET | 0.85460878 |
| 49 | MAP2K4 | 0.83901040 |
| 50 | MAP2K6 | 0.83823094 |
| 51 | ITK | 0.83128081 |
| 52 | NEK6 | 0.82030016 |
| 53 | STK38 | 0.80617773 |
| 54 | EEF2K | 0.80363484 |
| 55 | ICK | 0.77951087 |
| 56 | SGK1 | 0.77814527 |
| 57 | ZAP70 | 0.77037976 |
| 58 | BMPR2 | 0.75293599 |
| 59 | PDPK1 | 0.74166911 |
| 60 | MAPK7 | 0.72872607 |
| 61 | JAK1 | 0.71864559 |
| 62 | MAP3K11 | 0.71395689 |
| 63 | MAP2K3 | 0.69900102 |
| 64 | MAP3K6 | 0.69172998 |
| 65 | TEC | 0.68743635 |
| 66 | MAPK10 | 0.67920189 |
| 67 | ERN1 | 0.66097942 |
| 68 | BRD4 | 0.64255538 |
| 69 | JAK2 | 0.62566361 |
| 70 | CDC42BPA | 0.61742234 |
| 71 | TAOK3 | 0.60919065 |
| 72 | FYN | 0.59971985 |
| 73 | HCK | 0.59026820 |
| 74 | GRK6 | 0.58914495 |
| 75 | PKN1 | 0.58897936 |
| 76 | ARAF | 0.58601331 |
| 77 | MAPK8 | 0.54815370 |
| 78 | CAMK2B | 0.54264042 |
| 79 | ALK | 0.52464409 |
| 80 | RPS6KA3 | 0.50558484 |
| 81 | CASK | 0.50126788 |
| 82 | MAP3K1 | 0.49919598 |
| 83 | ERBB2 | 0.49873820 |
| 84 | MAPK4 | 0.49849808 |
| 85 | CAMKK2 | 0.49801244 |
| 86 | FGFR2 | 0.47625917 |
| 87 | PRKCG | 0.47588580 |
| 88 | MAP3K9 | 0.45319942 |
| 89 | CDK15 | 0.43078305 |
| 90 | CAMK2A | 0.43002944 |
| 91 | CDK11A | 0.41365470 |
| 92 | PRKCQ | 0.40395618 |
| 93 | BLK | 0.40060019 |
| 94 | RPS6KA2 | 0.39452135 |
| 95 | PRKD2 | 0.38215957 |
| 96 | PINK1 | 0.37003545 |
| 97 | LCK | 0.36932674 |
| 98 | SMG1 | 0.36887410 |
| 99 | CDK18 | 0.36404861 |
| 100 | PRKCZ | 0.35280986 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.94855614 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.70771462 |
| 3 | Long-term potentiation_Homo sapiens_hsa04720 | 2.49399569 |
| 4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.29930242 |
| 5 | Morphine addiction_Homo sapiens_hsa05032 | 2.20900547 |
| 6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.19537138 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.18465584 |
| 8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.13942786 |
| 9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.04097882 |
| 10 | Insulin secretion_Homo sapiens_hsa04911 | 2.01324676 |
| 11 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.87803743 |
| 12 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.87325943 |
| 13 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.82070310 |
| 14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.72574735 |
| 15 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.71485313 |
| 16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.70023470 |
| 17 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.66854771 |
| 18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.64811492 |
| 19 | Salivary secretion_Homo sapiens_hsa04970 | 1.63343592 |
| 20 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.61910883 |
| 21 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.60322179 |
| 22 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.54586865 |
| 23 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.46502307 |
| 24 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.44330232 |
| 25 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.43218858 |
| 26 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.38177278 |
| 27 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.33358043 |
| 28 | Renin secretion_Homo sapiens_hsa04924 | 1.29408559 |
| 29 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.28290191 |
| 30 | Glioma_Homo sapiens_hsa05214 | 1.27491625 |
| 31 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.25819914 |
| 32 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.25166924 |
| 33 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.22406878 |
| 34 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.21014122 |
| 35 | Taste transduction_Homo sapiens_hsa04742 | 1.18425883 |
| 36 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.18079949 |
| 37 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.17898005 |
| 38 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.16181253 |
| 39 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.16057800 |
| 40 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.15427371 |
| 41 | Long-term depression_Homo sapiens_hsa04730 | 1.07306157 |
| 42 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.06547557 |
| 43 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.05667109 |
| 44 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.02494093 |
| 45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.99923510 |
| 46 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.99823112 |
| 47 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.97708464 |
| 48 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.96564375 |
| 49 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.94627240 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.93685451 |
| 51 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.91182949 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.91002944 |
| 53 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.89227587 |
| 54 | Melanogenesis_Homo sapiens_hsa04916 | 0.88510461 |
| 55 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.87536068 |
| 56 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.87437968 |
| 57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.85042880 |
| 58 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.82107106 |
| 59 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.81088549 |
| 60 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.80239570 |
| 61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79887413 |
| 62 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.75339865 |
| 63 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.73851445 |
| 64 | Gap junction_Homo sapiens_hsa04540 | 0.71707232 |
| 65 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.71572719 |
| 66 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.71154485 |
| 67 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.69908906 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.67882922 |
| 69 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.66778314 |
| 70 | Alcoholism_Homo sapiens_hsa05034 | 0.65834407 |
| 71 | Other glycan degradation_Homo sapiens_hsa00511 | 0.65354977 |
| 72 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.65183480 |
| 73 | Platelet activation_Homo sapiens_hsa04611 | 0.64697437 |
| 74 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.62872447 |
| 75 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.62614758 |
| 76 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.60326256 |
| 77 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.59808906 |
| 78 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.59756214 |
| 79 | Endocytosis_Homo sapiens_hsa04144 | 0.58737503 |
| 80 | Tuberculosis_Homo sapiens_hsa05152 | 0.56234375 |
| 81 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.55217743 |
| 82 | Endometrial cancer_Homo sapiens_hsa05213 | 0.54537348 |
| 83 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53355520 |
| 84 | Leishmaniasis_Homo sapiens_hsa05140 | 0.49037584 |
| 85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.48730854 |
| 86 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.47568885 |
| 87 | Axon guidance_Homo sapiens_hsa04360 | 0.47556447 |
| 88 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.46941393 |
| 89 | Phototransduction_Homo sapiens_hsa04744 | 0.46464102 |
| 90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.45829674 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45619501 |
| 92 | Bile secretion_Homo sapiens_hsa04976 | 0.45592638 |
| 93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.45288098 |
| 94 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44077603 |
| 95 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.43476566 |
| 96 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.38725420 |
| 97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.38297030 |
| 98 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37652108 |
| 99 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.37537471 |
| 100 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.35654848 |

