TTC23L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.61889552
2spermatid development (GO:0007286)9.56736109
3cilium movement (GO:0003341)8.61798791
4regulation of cilium movement (GO:0003352)8.27880268
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.06146842
6single fertilization (GO:0007338)7.81047893
7piRNA metabolic process (GO:0034587)7.38921471
8sperm capacitation (GO:0048240)7.27219090
9male meiosis (GO:0007140)7.19916170
10synaptonemal complex organization (GO:0070193)7.16071975
11synaptonemal complex assembly (GO:0007130)7.03757576
12fertilization (GO:0009566)6.49549335
13spermatogenesis (GO:0007283)6.46467178
14male gamete generation (GO:0048232)6.44037003
15microtubule depolymerization (GO:0007019)6.42987064
16negative regulation of inclusion body assembly (GO:0090084)6.36509907
17organic cation transport (GO:0015695)6.01726150
18gamete generation (GO:0007276)5.92576961
19calcium ion-dependent exocytosis (GO:0017156)5.41335289
20response to pheromone (GO:0019236)5.39328715
21germ cell development (GO:0007281)5.36574103
22regulation of inclusion body assembly (GO:0090083)5.34181265
23cellular process involved in reproduction in multicellular organism (GO:0022412)5.32886542
24ventricular system development (GO:0021591)5.22091351
25spermatid nucleus differentiation (GO:0007289)5.16539406
26cell recognition (GO:0008037)5.05714905
27regulation of microtubule-based movement (GO:0060632)4.86546230
28glycerol ether metabolic process (GO:0006662)4.85215206
29chromosome organization involved in meiosis (GO:0070192)4.81625472
30DNA methylation involved in gamete generation (GO:0043046)4.74061655
31male meiosis I (GO:0007141)4.70800346
32multicellular organismal reproductive process (GO:0048609)4.66381617
33microtubule severing (GO:0051013)4.50178174
34nonmotile primary cilium assembly (GO:0035058)4.49188666
35ether metabolic process (GO:0018904)4.47874023
36left/right pattern formation (GO:0060972)4.26402644
37seminiferous tubule development (GO:0072520)4.25971981
38meiotic nuclear division (GO:0007126)4.21792501
39sexual reproduction (GO:0019953)4.19434557
40chromosome condensation (GO:0030261)4.12535651
41single strand break repair (GO:0000012)4.08032466
42monoubiquitinated protein deubiquitination (GO:0035520)3.99532224
43protein K11-linked deubiquitination (GO:0035871)3.95904701
44retinal rod cell development (GO:0046548)3.94987624
45DNA packaging (GO:0006323)3.92106282
46multicellular organismal development (GO:0007275)3.79673764
47genitalia morphogenesis (GO:0035112)3.73750113
48chaperone-mediated protein complex assembly (GO:0051131)3.72743382
49meiosis I (GO:0007127)3.72260015
50sequestering of actin monomers (GO:0042989)3.47415381
51meiotic cell cycle (GO:0051321)3.40071460
52establishment of protein localization to Golgi (GO:0072600)3.39124146
53protein targeting to Golgi (GO:0000042)3.37603997
54somite development (GO:0061053)3.35401474
55microtubule polymerization or depolymerization (GO:0031109)3.32769569
56photoreceptor cell maintenance (GO:0045494)3.29415784
57nucleoside diphosphate phosphorylation (GO:0006165)3.29404680
58DNA integration (GO:0015074)3.27976317
59alditol metabolic process (GO:0019400)3.26211901
60protein polyglutamylation (GO:0018095)3.23494414
61rRNA methylation (GO:0031167)3.21816822
62GTP biosynthetic process (GO:0006183)3.17227988
63protein localization to cilium (GO:0061512)3.16910606
64polyol catabolic process (GO:0046174)3.15696088
65regulation of glucokinase activity (GO:0033131)3.12814994
66regulation of hexokinase activity (GO:1903299)3.12814994
67smoothened signaling pathway (GO:0007224)3.10296054
68glycolytic process (GO:0006096)3.07740834
69G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06094864
70left/right axis specification (GO:0070986)3.03815827
71microtubule bundle formation (GO:0001578)3.02309620
72regulation of timing of cell differentiation (GO:0048505)3.01782290
73cilium organization (GO:0044782)2.98726634
74cellular ketone body metabolic process (GO:0046950)2.97270408
75regulation of spindle checkpoint (GO:0090231)2.97145618
76nucleus organization (GO:0006997)2.96668151
77protein refolding (GO:0042026)2.95983611
78retrograde transport, vesicle recycling within Golgi (GO:0000301)2.95785114
79regulation of development, heterochronic (GO:0040034)2.95430736
80rRNA modification (GO:0000154)2.94458621
81cilium morphogenesis (GO:0060271)2.91368971
82cilium assembly (GO:0042384)2.89290330
83carnitine transport (GO:0015879)2.86846617
84amino-acid betaine transport (GO:0015838)2.86846617
85centriole assembly (GO:0098534)2.86845564
86microtubule-based movement (GO:0007018)2.86680706
87glycerol metabolic process (GO:0006071)2.84171299
88cellular component assembly involved in morphogenesis (GO:0010927)2.83257256
89intraciliary transport (GO:0042073)2.82345192
90UTP biosynthetic process (GO:0006228)2.80356438
91lactate metabolic process (GO:0006089)2.80138057
92meiotic cell cycle process (GO:1903046)2.78980907
93axoneme assembly (GO:0035082)2.78724439
94phenol-containing compound catabolic process (GO:0019336)2.78429990
95ketone body metabolic process (GO:1902224)2.77507920
96DNA double-strand break processing (GO:0000729)2.75259604
97spinal cord motor neuron differentiation (GO:0021522)2.75100177
98synapsis (GO:0007129)2.74699966
99mitotic sister chromatid cohesion (GO:0007064)2.73207349
100carnitine transmembrane transport (GO:1902603)2.71332748
101negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.70598567
102negative regulation of translation, ncRNA-mediated (GO:0040033)2.70598567
103regulation of translation, ncRNA-mediated (GO:0045974)2.70598567
104protein localization to Golgi apparatus (GO:0034067)2.68832175
105interferon-gamma secretion (GO:0072643)2.67226935
106negative regulation of organelle assembly (GO:1902116)2.66826035
107lung-associated mesenchyme development (GO:0060484)2.65769998
108gene silencing by RNA (GO:0031047)2.63064245
109cell projection assembly (GO:0030031)2.61277051
110neuron fate determination (GO:0048664)2.60948782
111regulation of mesenchymal cell apoptotic process (GO:2001053)2.55956276
112phosphatidylethanolamine biosynthetic process (GO:0006646)2.55905811
113presynaptic membrane assembly (GO:0097105)2.54121111
114negative regulation of transcription regulatory region DNA binding (GO:2000678)2.52177362
115UTP metabolic process (GO:0046051)2.51108790
116retinal cone cell development (GO:0046549)2.50181037
117photoreceptor cell development (GO:0042461)2.48662858
118phosphatidylethanolamine metabolic process (GO:0046337)2.48355473
119regulation of mitochondrial translation (GO:0070129)2.46440429
120regulation of cilium assembly (GO:1902017)2.45841045
121pyrimidine nucleobase catabolic process (GO:0006208)2.45159258
122regulation of transcription involved in cell fate commitment (GO:0060850)2.42715723
123positive regulation of macrophage activation (GO:0043032)2.41241887
124adult feeding behavior (GO:0008343)2.41041221
125limb development (GO:0060173)2.40862507
126appendage development (GO:0048736)2.40862507
127thalamus development (GO:0021794)2.38913599
128centriole replication (GO:0007099)2.38705487
129single-organism membrane fusion (GO:0044801)2.38123301
130nuclear pore complex assembly (GO:0051292)2.37397748
131mitochondrial fission (GO:0000266)2.36286577
132retinal ganglion cell axon guidance (GO:0031290)2.34902248
133limb bud formation (GO:0060174)2.34869911
134determination of left/right symmetry (GO:0007368)2.33616149
135negative regulation of oligodendrocyte differentiation (GO:0048715)2.32887415
136RNA destabilization (GO:0050779)2.32199656
137regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.31798529
138C4-dicarboxylate transport (GO:0015740)2.31284394
139calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.30794298
140fusion of sperm to egg plasma membrane (GO:0007342)14.5577086
141sperm motility (GO:0030317)13.8518457
142cell wall macromolecule metabolic process (GO:0044036)13.3880021
143cell wall macromolecule catabolic process (GO:0016998)13.3880021
144multicellular organism reproduction (GO:0032504)11.7995992
145acrosome assembly (GO:0001675)11.7749675
146sperm-egg recognition (GO:0035036)11.6393875
147acrosome reaction (GO:0007340)11.6116811
148plasma membrane fusion (GO:0045026)11.0941928
149epithelial cilium movement (GO:0003351)10.5952858
150binding of sperm to zona pellucida (GO:0007339)10.5892789
151cilium or flagellum-dependent cell motility (GO:0001539)10.5099068
152cell-cell recognition (GO:0009988)10.4391486
153axonemal dynein complex assembly (GO:0070286)10.2123201
154reproduction (GO:0000003)10.1095428

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.34349461
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.18249322
3EZH2_22144423_ChIP-Seq_EOC_Human3.80010032
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.34076939
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.11637896
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.78812180
7IGF1R_20145208_ChIP-Seq_DFB_Human2.72986828
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.62410557
9STAT6_21828071_ChIP-Seq_BEAS2B_Human2.58808810
10FUS_26573619_Chip-Seq_HEK293_Human2.55352064
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.52090854
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.42753666
13CTBP1_25329375_ChIP-Seq_LNCAP_Human2.40731804
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.36831515
15VDR_22108803_ChIP-Seq_LS180_Human2.30724363
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.29241878
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.25365971
18P300_19829295_ChIP-Seq_ESCs_Human2.21941808
19GBX2_23144817_ChIP-Seq_PC3_Human2.18754596
20PCGF2_27294783_Chip-Seq_ESCs_Mouse2.14400430
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.05557756
22RBPJ_22232070_ChIP-Seq_NCS_Mouse1.96226011
23CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.95233479
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.94574685
25KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.91924340
26ER_23166858_ChIP-Seq_MCF-7_Human1.86156233
27CBX2_27304074_Chip-Seq_ESCs_Mouse1.82589518
28STAT1_17558387_ChIP-Seq_HELA_Human1.82149539
29ZNF274_21170338_ChIP-Seq_K562_Hela1.81693607
30EWS_26573619_Chip-Seq_HEK293_Human1.81219838
31GATA1_26923725_Chip-Seq_HPCs_Mouse1.80968350
32RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.76486130
33KAP1_22055183_ChIP-Seq_ESCs_Mouse1.74991394
34TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.70786180
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.69094434
36SMAD3_21741376_ChIP-Seq_EPCs_Human1.69058110
37MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.69013803
38SMAD4_21799915_ChIP-Seq_A2780_Human1.68440527
39TOP2B_26459242_ChIP-Seq_MCF-7_Human1.67938797
40ELK4_26923725_Chip-Seq_MESODERM_Mouse1.66034794
41KDM2B_26808549_Chip-Seq_REH_Human1.63408501
42AR_25329375_ChIP-Seq_VCAP_Human1.62128248
43PCGF2_27294783_Chip-Seq_NPCs_Mouse1.60929967
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.59314778
45* TAL1_26923725_Chip-Seq_HPCs_Mouse1.58849801
46AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.57483103
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.57290859
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.57242263
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54843822
50GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.53916153
51STAT3_23295773_ChIP-Seq_U87_Human1.53045578
52SOX2_22085726_ChIP-Seq_NPCs_Mouse1.52804188
53WDR5_24793694_ChIP-Seq_LNCAP_Human1.52180956
54SUZ12_27294783_Chip-Seq_NPCs_Mouse1.49967920
55ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.49261240
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46574601
57TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.46399999
58GATA3_21867929_ChIP-Seq_CD8_Mouse1.46026629
59* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42828572
60TP63_19390658_ChIP-ChIP_HaCaT_Human1.41540852
61* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40074450
62* RUNX2_22187159_ChIP-Seq_PCA_Human1.39005526
63CBP_20019798_ChIP-Seq_JUKART_Human1.38947772
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38947772
65PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37073125
66ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36694249
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.33242033
68GATA3_21867929_ChIP-Seq_TH1_Mouse1.32178282
69SOX2_19829295_ChIP-Seq_ESCs_Human1.31411892
70NANOG_19829295_ChIP-Seq_ESCs_Human1.31411892
71* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.31292368
72TCF4_23295773_ChIP-Seq_U87_Human1.29475468
73NR3C1_21868756_ChIP-Seq_MCF10A_Human1.29103166
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.28145886
75CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27012275
76CRX_20693478_ChIP-Seq_RETINA_Mouse1.26756229
77SMAD4_21741376_ChIP-Seq_EPCs_Human1.25534791
78FLI1_21867929_ChIP-Seq_TH2_Mouse1.25169557
79LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.24988559
80* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.23875569
81REST_21632747_ChIP-Seq_MESCs_Mouse1.23839448
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23065184
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.23000240
84TAF15_26573619_Chip-Seq_HEK293_Human1.22027535
85CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21767855
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21731547
87P53_21459846_ChIP-Seq_SAOS-2_Human1.19380992
88CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18455704
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18234361
90TBL1_22424771_ChIP-Seq_293T_Human1.18031337
91* TCF4_22108803_ChIP-Seq_LS180_Human1.17961012
92P53_22387025_ChIP-Seq_ESCs_Mouse1.17587698
93AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16258379
94OCT4_18555785_Chip-Seq_ESCs_Mouse1.15214590
95CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14999777
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14653768
97SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.13622866
98EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13257013
99RNF2_27304074_Chip-Seq_NSC_Mouse1.13208008
100* GF1_26923725_Chip-Seq_HPCs_Mouse1.13142691
101CMYC_18555785_Chip-Seq_ESCs_Mouse1.12936081
102TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12597699
103EZH2_27294783_Chip-Seq_NPCs_Mouse1.12472990
104SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12454676
105PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11503619
106* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11184939
107SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11097658
108ETV1_20927104_ChIP-Seq_GIST48_Human1.09569583
109AR_21572438_ChIP-Seq_LNCaP_Human1.09512940
110MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08740589
111ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08512218
112P300_18555785_Chip-Seq_ESCs_Mouse1.08378046
113PHF8_20622853_ChIP-Seq_HELA_Human1.08237455
114TP53_18474530_ChIP-ChIP_U2OS_Human1.08118724
115PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.07440893
116POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07361465
117POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07226218
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07226218
119OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06777323
120* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.06650021
121IRF1_19129219_ChIP-ChIP_H3396_Human1.06100122
122RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05857924
123SMAD3_21741376_ChIP-Seq_ESCs_Human1.04945128
124FOXA1_25329375_ChIP-Seq_VCAP_Human1.04159224
125FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04159224
126OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03956129
127PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.03861793
128NFYA_21822215_ChIP-Seq_K562_Human1.03750783
129CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.03304447
130KLF4_18555785_Chip-Seq_ESCs_Mouse1.03137387
131EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.02367508
132RBPJ_21746931_ChIP-Seq_IB4_Human1.02291594
133TP53_22573176_ChIP-Seq_HFKS_Human1.01791737
134HNFA_21074721_ChIP-Seq_CACO-2_Human1.01707303
135ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01577810
136SPI1_26923725_Chip-Seq_HPCs_Mouse1.01377889
137CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.01216830
138CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01051467
139CBX2_22325352_ChIP-Seq_293T-Rex_Human1.00682860
140BCAT_22108803_ChIP-Seq_LS180_Human1.00647417
141SUZ12_18555785_Chip-Seq_ESCs_Mouse1.00606026
142STAT3_18555785_Chip-Seq_ESCs_Mouse0.99373447
143EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.98451307
144* NCOR_22424771_ChIP-Seq_293T_Human0.97698393
145GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.97665451
146* ESET_19884257_ChIP-Seq_ESCs_Mouse0.97606402
147PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97569316
148* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97214832
149PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97143621
150SOX2_18555785_Chip-Seq_ESCs_Mouse0.96553454
151EZH2_27304074_Chip-Seq_ESCs_Mouse0.96514021
152PU1_27457419_Chip-Seq_LIVER_Mouse0.95401287
153SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95114822
154ERG_20517297_ChIP-Seq_VCAP_Human0.94955089
155NFYB_21822215_ChIP-Seq_K562_Human0.94891183
156* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94002068
157SOX9_26525672_Chip-Seq_HEART_Mouse0.91989563
158MYC_27129775_Chip-Seq_CORNEA_Mouse0.91859867
159KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.91336887
160LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.89946539
161STAT3_18555785_ChIP-Seq_MESCs_Mouse0.89848436
162NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89575477
163* GF1B_26923725_Chip-Seq_HPCs_Mouse0.89549650
164CTCF_18555785_Chip-Seq_ESCs_Mouse0.88589751
165E2F1_18555785_Chip-Seq_ESCs_Mouse0.88297532

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.15677929
2MP0001929_abnormal_gametogenesis5.62845654
3MP0008877_abnormal_DNA_methylation4.19330985
4MP0002210_abnormal_sex_determination3.52101362
5MP0002161_abnormal_fertility/fecundity3.37153756
6MP0000566_synostosis3.17088784
7MP0001145_abnormal_male_reproductive2.94826704
8MP0006292_abnormal_olfactory_placode2.63074259
9MP0005670_abnormal_white_adipose2.62660661
10MP0000653_abnormal_sex_gland2.55804639
11MP0008789_abnormal_olfactory_epithelium2.53142601
12MP0005499_abnormal_olfactory_system2.35316738
13MP0005394_taste/olfaction_phenotype2.35316738
14MP0003880_abnormal_central_pattern2.34216462
15MP0002653_abnormal_ependyma_morphology2.31952627
16MP0002938_white_spotting2.08810359
17MP0005410_abnormal_fertilization16.4948543
18MP0006072_abnormal_retinal_apoptosis1.99782454
19MP0003122_maternal_imprinting1.97257046
20MP0000372_irregular_coat_pigmentation1.93265678
21MP0001485_abnormal_pinna_reflex1.91098369
22MP0006276_abnormal_autonomic_nervous1.84253693
23MP0003136_yellow_coat_color1.79422255
24MP0001529_abnormal_vocalization1.75721171
25MP0002822_catalepsy1.68583603
26MP0001486_abnormal_startle_reflex1.61318273
27MP0002638_abnormal_pupillary_reflex1.55157093
28MP0005623_abnormal_meninges_morphology1.55152616
29MP0005248_abnormal_Harderian_gland1.51169580
30MP0003195_calcinosis1.44792913
31MP0003121_genomic_imprinting1.42980174
32MP0002160_abnormal_reproductive_system1.41095407
33MP0000049_abnormal_middle_ear1.39878274
34MP0008995_early_reproductive_senescence1.39088931
35MP0002282_abnormal_trachea_morphology1.38716877
36MP0003283_abnormal_digestive_organ1.37504311
37MP0002735_abnormal_chemical_nociception1.37086492
38MP0000778_abnormal_nervous_system1.34242319
39MP0000026_abnormal_inner_ear1.31925470
40MP0003718_maternal_effect1.31167507
41MP0000631_abnormal_neuroendocrine_gland1.26762400
42MP0001765_abnormal_ion_homeostasis1.25907440
43MP0002233_abnormal_nose_morphology1.24000336
44MP0008058_abnormal_DNA_repair1.21075302
45MP0002751_abnormal_autonomic_nervous1.20839167
46MP0005645_abnormal_hypothalamus_physiol1.20373279
47MP0002272_abnormal_nervous_system1.20101568
48MP0003937_abnormal_limbs/digits/tail_de1.19797275
49MP0002557_abnormal_social/conspecific_i1.16791969
50MP0001963_abnormal_hearing_physiology1.16535484
51MP0001984_abnormal_olfaction1.14596713
52MP0003646_muscle_fatigue1.12443327
53MP0005408_hypopigmentation1.10997502
54MP0002572_abnormal_emotion/affect_behav1.07081629
55MP0001286_abnormal_eye_development1.06570999
56MP0009745_abnormal_behavioral_response1.06405242
57MP0002734_abnormal_mechanical_nocicepti1.05191225
58MP0004233_abnormal_muscle_weight1.03049052
59MP0005379_endocrine/exocrine_gland_phen1.02832178
60MP0005647_abnormal_sex_gland1.01649035
61MP0005646_abnormal_pituitary_gland0.98616036
62MP0005195_abnormal_posterior_eye0.98229720
63MP0000955_abnormal_spinal_cord0.98051760
64MP0000383_abnormal_hair_follicle0.96267554
65MP0003938_abnormal_ear_development0.95402588
66MP0002752_abnormal_somatic_nervous0.94964951
67MP0002067_abnormal_sensory_capabilities0.92758149
68MP0005171_absent_coat_pigmentation0.92507930
69MP0004270_analgesia0.88197570
70MP0003119_abnormal_digestive_system0.87122353
71MP0003635_abnormal_synaptic_transmissio0.85742019
72MP0002184_abnormal_innervation0.85729578
73MP0003755_abnormal_palate_morphology0.85648991
74MP0008875_abnormal_xenobiotic_pharmacok0.82551376
75MP0001970_abnormal_pain_threshold0.81624680
76MP0001299_abnormal_eye_distance/0.81112627
77MP0002882_abnormal_neuron_morphology0.79098429
78MP0003567_abnormal_fetal_cardiomyocyte0.79040846
79MP0002733_abnormal_thermal_nociception0.76961610
80MP0004085_abnormal_heartbeat0.76659924
81MP0003011_delayed_dark_adaptation0.76231996
82MP0003115_abnormal_respiratory_system0.75940475
83MP0009046_muscle_twitch0.75569454
84MP0002229_neurodegeneration0.75435914
85MP0000647_abnormal_sebaceous_gland0.75352843
86MP0001188_hyperpigmentation0.75015351
87MP0004859_abnormal_synaptic_plasticity0.73942887
88MP0002095_abnormal_skin_pigmentation0.73740920
89MP0005636_abnormal_mineral_homeostasis0.72899913
90MP0005389_reproductive_system_phenotype0.68040091
91MP0002234_abnormal_pharynx_morphology0.64177605
92MP0002928_abnormal_bile_duct0.63165290
93MP0001324_abnormal_eye_pigmentation0.57212920
94MP0000569_abnormal_digit_pigmentation0.55581803
95MP0010094_abnormal_chromosome_stability0.53321145
96MP0003786_premature_aging0.52984737
97MP0003878_abnormal_ear_physiology0.52183544
98MP0005377_hearing/vestibular/ear_phenot0.52183544
99MP0001764_abnormal_homeostasis0.51578610
100MP0003699_abnormal_female_reproductive0.49989960
101MP0005253_abnormal_eye_physiology0.49146776
102MP0000358_abnormal_cell_content/0.46297133
103MP0009115_abnormal_fat_cell0.43847349
104MP0001119_abnormal_female_reproductive0.43210674
105MP0001293_anophthalmia0.42866972
106MP0003045_fibrosis0.42154088
107MP0005551_abnormal_eye_electrophysiolog0.42111320
108MP0002102_abnormal_ear_morphology0.41900185
109MP0005397_hematopoietic_system_phenotyp0.40540307
110MP0001545_abnormal_hematopoietic_system0.40540307
111MP0005666_abnormal_adipose_tissue0.39179285
112MP0002736_abnormal_nociception_after0.38027842
113MP0002269_muscular_atrophy0.37319823
114MP0004019_abnormal_vitamin_homeostasis0.36867520
115MP0004036_abnormal_muscle_relaxation0.35032526
116MP0003111_abnormal_nucleus_morphology0.34832879
117MP0003950_abnormal_plasma_membrane0.34667534
118MP0001270_distended_abdomen0.34255342
119MP0009278_abnormal_bone_marrow0.33823542
120MP0005391_vision/eye_phenotype0.33062834
121MP0002971_abnormal_brown_adipose0.31824051
122MP0008057_abnormal_DNA_replication0.30664970
123MP0008007_abnormal_cellular_replicative0.29565444
124MP0003329_amyloid_beta_deposits0.28835026
125MP0003879_abnormal_hair_cell0.27151593
126MP0004133_heterotaxia0.26949050
127MP0003942_abnormal_urinary_system0.26667048
128MP0003252_abnormal_bile_duct0.25635008
129MP0003787_abnormal_imprinting0.24205917
130MP0002405_respiratory_system_inflammati0.23133288
131MP0002139_abnormal_hepatobiliary_system0.22696298
132MP0004742_abnormal_vestibular_system0.22070261
133MP0001986_abnormal_taste_sensitivity0.21924394
134MP0002132_abnormal_respiratory_system0.21885735
135MP0004145_abnormal_muscle_electrophysio0.20745314
136MP0002169_no_abnormal_phenotype0.20563223
137MP0003948_abnormal_gas_homeostasis0.20504257
138MP0002873_normal_phenotype0.20321817
139MP0000534_abnormal_ureter_morphology0.19992927
140MP0001542_abnormal_bone_strength0.19723232
141MP0002693_abnormal_pancreas_physiology0.19502666
142MP0004134_abnormal_chest_morphology0.18508006
143MP0003861_abnormal_nervous_system0.18470008
144MP0005388_respiratory_system_phenotype0.18341688
145MP0002133_abnormal_respiratory_system0.18341688
146MP0003279_aneurysm0.18264961
147MP0003633_abnormal_nervous_system0.18037431
148MP0010307_abnormal_tumor_latency0.17322283
149MP0001849_ear_inflammation0.16988503
150MP0009250_abnormal_appendicular_skeleto0.16596232
151MP0002295_abnormal_pulmonary_circulatio0.16357005
152MP0003959_abnormal_lean_body0.15638584
153MP0004811_abnormal_neuron_physiology0.15557520
154MP0001502_abnormal_circadian_rhythm0.15229398
155MP0000313_abnormal_cell_death0.15086124
156MP0006036_abnormal_mitochondrial_physio0.14962722
157MP0003631_nervous_system_phenotype0.14480890
158MP0002152_abnormal_brain_morphology0.14046348
159MP0000604_amyloidosis0.13788806
160MP0001968_abnormal_touch/_nociception0.13298536
161MP0005423_abnormal_somatic_nervous0.13228418
162MP0000432_abnormal_head_morphology0.12522488
163MP0002092_abnormal_eye_morphology0.12176016
164MP0000001_mammalian_phenotype0.10727953
165MP0008961_abnormal_basal_metabolism0.10448607

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.40789268
2Abnormal respiratory motile cilium morphology (HP:0005938)9.39367456
3Abnormal respiratory epithelium morphology (HP:0012253)9.39367456
4Abnormal ciliary motility (HP:0012262)7.68148086
5Chronic bronchitis (HP:0004469)7.63067221
6Rhinitis (HP:0012384)7.43311386
7Infertility (HP:0000789)6.53553845
8Nasal polyposis (HP:0100582)6.08230814
9Abnormality of the nasal mucosa (HP:0000433)4.97080087
10Bronchitis (HP:0012387)4.54985363
11Bronchiectasis (HP:0002110)4.39184386
12Male infertility (HP:0003251)4.35044608
13Nephronophthisis (HP:0000090)4.10037098
14Recurrent sinusitis (HP:0011108)3.62098449
15Abnormal spermatogenesis (HP:0008669)3.33136741
16Occipital encephalocele (HP:0002085)3.24003922
17Abnormality of the renal medulla (HP:0100957)3.22877462
18Tubulointerstitial nephritis (HP:0001970)3.22204456
19Recurrent otitis media (HP:0000403)3.20018878
20Poor coordination (HP:0002370)2.89843701
21Molar tooth sign on MRI (HP:0002419)2.67202596
22Abnormality of midbrain morphology (HP:0002418)2.67202596
23Anencephaly (HP:0002323)2.59941666
24Tubular atrophy (HP:0000092)2.58131113
25Concave nail (HP:0001598)2.51386639
26Recurrent bronchitis (HP:0002837)2.49597457
27Medial flaring of the eyebrow (HP:0010747)2.47205816
28Bony spicule pigmentary retinopathy (HP:0007737)2.46662132
29Abnormality of macular pigmentation (HP:0008002)2.46610258
30Severe visual impairment (HP:0001141)2.43193513
31Tubulointerstitial abnormality (HP:0001969)2.41951700
32Attenuation of retinal blood vessels (HP:0007843)2.40297870
33Impulsivity (HP:0100710)2.35929371
34Gonadotropin excess (HP:0000837)2.32134563
35Intestinal atresia (HP:0011100)2.30240224
36Preaxial hand polydactyly (HP:0001177)2.18419748
37Azoospermia (HP:0000027)2.17956597
38Sclerocornea (HP:0000647)2.17175652
39Abnormality of the labia minora (HP:0012880)2.16071037
40Abnormality of the renal cortex (HP:0011035)2.11014335
41Optic nerve hypoplasia (HP:0000609)2.08207988
42Congenital stationary night blindness (HP:0007642)2.07422745
43Oligodactyly (hands) (HP:0001180)2.06851315
44Male pseudohermaphroditism (HP:0000037)2.03200641
45Dynein arm defect of respiratory motile cilia (HP:0012255)13.8121947
46Absent/shortened dynein arms (HP:0200106)13.8121947
47Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2019221
48Specific learning disability (HP:0001328)1.98330571
49Stage 5 chronic kidney disease (HP:0003774)1.97807811
50Broad foot (HP:0001769)1.93037520
51Postaxial foot polydactyly (HP:0001830)1.90627127
52Tubulointerstitial fibrosis (HP:0005576)1.88288898
53Abnormal rod and cone electroretinograms (HP:0008323)1.87476938
54Abnormality of the parathyroid morphology (HP:0011766)1.87067819
55Abnormal gallbladder physiology (HP:0012438)1.86456045
56Cholecystitis (HP:0001082)1.86456045
57Dyschromatopsia (HP:0007641)1.85283330
58Anophthalmia (HP:0000528)1.84742793
59Prominent nasal bridge (HP:0000426)1.83567203
60Aganglionic megacolon (HP:0002251)1.79446333
61Decreased central vision (HP:0007663)1.77181934
62Growth hormone deficiency (HP:0000824)1.77087691
63Astigmatism (HP:0000483)1.76882258
64Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76684715
65Cystic liver disease (HP:0006706)1.76236156
66Congenital hepatic fibrosis (HP:0002612)1.76189583
67Retinitis pigmentosa (HP:0000510)1.72737740
68Multicystic kidney dysplasia (HP:0000003)1.72407340
69Absent speech (HP:0001344)1.71653990
70Pendular nystagmus (HP:0012043)1.70701960
71Median cleft lip (HP:0000161)1.70195379
72Choroideremia (HP:0001139)1.70177837
73Spastic tetraparesis (HP:0001285)1.69988439
74Abnormality of abdominal situs (HP:0011620)1.69720892
75Abdominal situs inversus (HP:0003363)1.69720892
76Progressive cerebellar ataxia (HP:0002073)1.69701439
77Polyphagia (HP:0002591)1.69255157
78Bile duct proliferation (HP:0001408)1.68139840
79Abnormal biliary tract physiology (HP:0012439)1.68139840
80Abnormality of the fovea (HP:0000493)1.67823731
81Narrow forehead (HP:0000341)1.67189068
82Polyuria (HP:0000103)1.66638011
83Abnormality of permanent molar morphology (HP:0011071)1.66475193
84Abnormality of the dental root (HP:0006486)1.66475193
85Taurodontia (HP:0000679)1.66475193
86Abnormality of renal excretion (HP:0011036)1.65392158
87Gastrointestinal atresia (HP:0002589)1.65037012
88Hyperglycinemia (HP:0002154)1.64122282
89Acute encephalopathy (HP:0006846)1.62817839
90Heterotopia (HP:0002282)1.61893805
91Retrobulbar optic neuritis (HP:0100654)1.61544754
92Optic neuritis (HP:0100653)1.61544754
93Intellectual disability, moderate (HP:0002342)1.59402689
94Asthma (HP:0002099)1.58852098
95Asymmetric septal hypertrophy (HP:0001670)1.57970699
96Aplasia/Hypoplasia of the fovea (HP:0008060)1.57349757
97Hypoplasia of the fovea (HP:0007750)1.57349757
98Oligodactyly (HP:0012165)1.57314970
99Aplasia/Hypoplasia of the earlobes (HP:0009906)1.57035028
100Abnormality of molar (HP:0011077)1.56411415
101Abnormality of molar morphology (HP:0011070)1.56411415
102Type II lissencephaly (HP:0007260)1.56222377
103Facial cleft (HP:0002006)1.55981608
104Fibular hypoplasia (HP:0003038)1.55149717
105Decreased testicular size (HP:0008734)1.54425582
106Oculomotor apraxia (HP:0000657)1.54318993
107Acute necrotizing encephalopathy (HP:0006965)1.54041516
108Abnormality of the dental pulp (HP:0006479)1.53202696
109Aplasia/Hypoplasia of the lens (HP:0008063)1.53076282
110Bell-shaped thorax (HP:0001591)1.51149683
111Abnormal drinking behavior (HP:0030082)1.49682562
112Polydipsia (HP:0001959)1.49682562
113Pancreatic fibrosis (HP:0100732)1.49334581
114Congenital primary aphakia (HP:0007707)1.47904137
115Gait imbalance (HP:0002141)1.46466930
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.46096870
117Short ribs (HP:0000773)1.45927517
118Postaxial hand polydactyly (HP:0001162)1.44375553
119True hermaphroditism (HP:0010459)1.42269090
120Aplasia/Hypoplasia of the tongue (HP:0010295)1.38860700
121Hemorrhage of the eye (HP:0011885)1.37357955
122Abnormality of the lower motor neuron (HP:0002366)1.34463021
123Abnormality of dentin (HP:0010299)1.34245945
124Orchitis (HP:0100796)1.32613334
125Chronic sinusitis (HP:0011109)1.32077377
126Renal dysplasia (HP:0000110)1.31856341
127Constricted visual fields (HP:0001133)1.30327383
128Absent frontal sinuses (HP:0002688)1.27234283
129Nephrogenic diabetes insipidus (HP:0009806)1.26902014
130Short thorax (HP:0010306)1.26428433
131Microglossia (HP:0000171)1.26027033
132Nephropathy (HP:0000112)1.25864160
133Bundle branch block (HP:0011710)1.25179417
134Vascular calcification (HP:0004934)1.24476866
135Congenital malformation of the right heart (HP:0011723)1.24288834
136Double outlet right ventricle (HP:0001719)1.24288834
137Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.21452849
138Amyotrophic lateral sclerosis (HP:0007354)1.20609817
139Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.19001856
140Absent epiphyses (HP:0010577)1.19001856
141Supernumerary spleens (HP:0009799)1.18945201
142Vaginal atresia (HP:0000148)1.17918086
143Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.16186897
144Abnormal urine output (HP:0012590)1.16074452
145Chronic hepatic failure (HP:0100626)1.15883257
146Pancreatic cysts (HP:0001737)1.15768574
147Genital tract atresia (HP:0001827)1.15594455
148Deformed sella turcica (HP:0002681)1.14148868
149Decreased electroretinogram (ERG) amplitude (HP:0000654)1.13848343
150Cardiovascular calcification (HP:0011915)1.10466793

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK39.10500388
2PDK49.10500388
3PDK26.05955514
4TESK15.11160184
5PRKD34.24335103
6ICK3.65564978
7MAP4K23.62343806
8CASK3.29344233
9MAP3K42.40207240
10TRIM282.16806160
11INSRR2.15257288
12FRK2.01122778
13WNK41.96774806
14EPHA41.95609692
15PTK2B1.90457744
16ERBB41.83271083
17BRD41.77859438
18PNCK1.72963779
19STK391.69408995
20TNIK1.66933085
21AKT31.66071995
22MAP2K71.60291732
23SRPK11.59081587
24DYRK21.50820127
25PLK21.50401681
26ERBB31.47488252
27DYRK1B1.38035981
28BCR1.37110443
29NUAK11.35979054
30NEK21.35544382
31STK381.34884296
32TSSK61.34707985
33BCKDK1.31792718
34MARK11.30662823
35STK161.30175939
36LATS11.23066154
37NTRK31.19711686
38ADRBK21.17376202
39PDK11.09405287
40VRK11.04896443
41GRK11.03881631
42RPS6KA41.02456822
43DDR21.00576061
44MAPK130.99612327
45CSNK1G10.96194861
46MKNK10.95913692
47CSNK1G20.93167698
48CSNK1A1L0.91562531
49IRAK10.86682498
50TTK0.85385749
51PASK0.82295441
52MKNK20.81907508
53WNK10.80161436
54MAPK150.79918189
55PLK30.78340671
56CSNK1G30.76662610
57SGK2230.76562838
58SGK4940.76562838
59DYRK30.73198266
60PRKCE0.72426058
61DYRK1A0.72067155
62RIPK40.69934117
63ACVR1B0.68091043
64PAK30.67426464
65STK30.66270590
66SGK20.65271167
67CHEK20.62088355
68MAP2K40.61161193
69MAP2K60.60730138
70LMTK20.59304393
71TYRO30.59258336
72ERBB20.56098836
73TIE10.55447018
74NME10.53426720
75FER0.53206254
76STK38L0.52093857
77PDPK10.51988086
78FGFR20.51495869
79MST40.49637775
80PBK0.49452316
81PINK10.48390078
82TESK20.47834549
83KSR10.47076561
84MINK10.46702880
85EPHA30.44790905
86UHMK10.44246957
87CCNB10.44084809
88PIK3CA0.42210538
89CAMK1G0.42178268
90CDK70.41611600
91CSNK1A10.39852580
92OXSR10.39740823
93ZAK0.39602491
94PLK40.37549274
95IRAK20.36972906
96CHEK10.36570999
97ADRBK10.35606972
98TGFBR10.35161569
99CDK50.33989918
100PAK10.33491013
101FLT30.32986613
102TAF10.31862039
103ATR0.31675342
104NEK60.29308008
105ATM0.28560871
106MUSK0.27934843
107EEF2K0.24583862
108CAMKK10.23746403
109PAK20.23417752
110TAOK10.22881095
111PLK10.21007292
112MTOR0.20400834
113PRKCG0.18900050
114STK100.16615872
115NTRK20.16308159
116MAP3K30.16249011
117YES10.16087753
118PRKAA10.15032134
119PIM10.12318848
120WEE10.10932601
121MAP3K50.10776598
122WNK30.10337865
123BMPR1B0.09857043
124MARK20.09614036
125BRAF0.09586727
126MARK30.09516549
127PRKCZ0.09501852
128CDC70.08989284
129MAPKAPK50.08945323
130PKN10.08837989
131PRKG10.08788371
132PRKCQ0.08428571
133PRKACG0.07546852
134PRKG20.06959156
135MAP3K100.06939083
136RPS6KB10.06001194
137PRKCD0.05795986
138GSK3B0.05324576
139CSNK2A10.04314976
140CDK120.04159718
141PIK3CG0.04127089
142ZAP700.03726296
143PAK40.03689544
144CSNK1D0.03565755
145EGFR0.03545985
146BRSK20.02979332
147RPS6KA10.02084280
148PRKCA0.01908363
149CSK0.01883196
150CDK10.00752026
151CDK20.00212976
152TGFBR20.00142677
153PDGFRB-0.0246649
154PRKCB-0.0244998
155PRKCH-0.0204568
156CDK18-0.0188518
157CDK3-0.0107302
158CAMK2A-0.0097890
159PRKACA-0.0087218
160BRSK1-0.0064739
161CSNK2A2-0.0063924
162PRKACB-0.0061068
163CDK6-0.0038049
164CDK15-0.0013799
165MAPK8-0.0010324

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.02955456
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.37879902
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.13592126
4Fatty acid biosynthesis_Homo sapiens_hsa000614.01197449
5Pyruvate metabolism_Homo sapiens_hsa006203.54847843
6Propanoate metabolism_Homo sapiens_hsa006402.89685063
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.79688192
8Butanoate metabolism_Homo sapiens_hsa006502.74416079
9Linoleic acid metabolism_Homo sapiens_hsa005912.73953723
10Glucagon signaling pathway_Homo sapiens_hsa049222.59482426
11Basal transcription factors_Homo sapiens_hsa030222.53770749
12Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.37932659
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.27340557
14Nicotine addiction_Homo sapiens_hsa050332.25091011
15Carbohydrate digestion and absorption_Homo sapiens_hsa049732.22001529
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.21797364
17Maturity onset diabetes of the young_Homo sapiens_hsa049502.16739360
18Glycosaminoglycan degradation_Homo sapiens_hsa005312.16035753
19Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.12248995
20Selenocompound metabolism_Homo sapiens_hsa004502.01603851
21Protein export_Homo sapiens_hsa030602.00281142
22Phototransduction_Homo sapiens_hsa047441.91719210
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.91584213
24Oxidative phosphorylation_Homo sapiens_hsa001901.91270582
25Glycerolipid metabolism_Homo sapiens_hsa005611.87106944
26Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.86850674
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.81083190
28Oocyte meiosis_Homo sapiens_hsa041141.73559999
29PPAR signaling pathway_Homo sapiens_hsa033201.71503527
30Pentose phosphate pathway_Homo sapiens_hsa000301.69385032
31Dorso-ventral axis formation_Homo sapiens_hsa043201.69034391
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64398566
33Fanconi anemia pathway_Homo sapiens_hsa034601.63132556
34Steroid biosynthesis_Homo sapiens_hsa001001.58332170
35Parkinsons disease_Homo sapiens_hsa050121.55500670
36RNA polymerase_Homo sapiens_hsa030201.55390409
37Olfactory transduction_Homo sapiens_hsa047401.55311830
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.54548366
39Primary bile acid biosynthesis_Homo sapiens_hsa001201.53870538
40Mineral absorption_Homo sapiens_hsa049781.49081577
41Homologous recombination_Homo sapiens_hsa034401.46233319
42Non-homologous end-joining_Homo sapiens_hsa034501.45922029
43Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.40595298
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.39779184
45Peroxisome_Homo sapiens_hsa041461.35602429
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.35120945
47Ether lipid metabolism_Homo sapiens_hsa005651.34478874
48Fructose and mannose metabolism_Homo sapiens_hsa000511.32605699
49Amphetamine addiction_Homo sapiens_hsa050311.31955432
50Caffeine metabolism_Homo sapiens_hsa002321.31085168
51Carbon metabolism_Homo sapiens_hsa012001.20908441
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20589950
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18760925
54Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.18208808
55Tryptophan metabolism_Homo sapiens_hsa003801.14543675
56Purine metabolism_Homo sapiens_hsa002301.11901259
57Cardiac muscle contraction_Homo sapiens_hsa042601.11217492
58Huntingtons disease_Homo sapiens_hsa050161.11196467
59beta-Alanine metabolism_Homo sapiens_hsa004101.09566056
60Nitrogen metabolism_Homo sapiens_hsa009101.08576122
61Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.07898365
62Fatty acid degradation_Homo sapiens_hsa000711.07450663
63Fatty acid metabolism_Homo sapiens_hsa012121.07381361
64Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05494045
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04737316
66Fat digestion and absorption_Homo sapiens_hsa049751.04450447
67Cysteine and methionine metabolism_Homo sapiens_hsa002701.03841314
68Collecting duct acid secretion_Homo sapiens_hsa049661.02360880
69Renin secretion_Homo sapiens_hsa049241.01399315
70Antigen processing and presentation_Homo sapiens_hsa046121.00798225
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.00318258
72Nucleotide excision repair_Homo sapiens_hsa034200.96571109
73Phenylalanine metabolism_Homo sapiens_hsa003600.94216036
74GABAergic synapse_Homo sapiens_hsa047270.94039430
75Arginine and proline metabolism_Homo sapiens_hsa003300.91633212
76Mismatch repair_Homo sapiens_hsa034300.90761782
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.90514596
78Glutamatergic synapse_Homo sapiens_hsa047240.90127086
79Hedgehog signaling pathway_Homo sapiens_hsa043400.89312045
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.87358849
81Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.86826810
82Cocaine addiction_Homo sapiens_hsa050300.86508171
83Histidine metabolism_Homo sapiens_hsa003400.84030112
84Tyrosine metabolism_Homo sapiens_hsa003500.83617591
85Circadian rhythm_Homo sapiens_hsa047100.83107623
86Glutathione metabolism_Homo sapiens_hsa004800.81245185
87Arachidonic acid metabolism_Homo sapiens_hsa005900.80779700
88Alzheimers disease_Homo sapiens_hsa050100.79815223
89mRNA surveillance pathway_Homo sapiens_hsa030150.79276000
90Morphine addiction_Homo sapiens_hsa050320.78329034
91RNA degradation_Homo sapiens_hsa030180.77420956
92Base excision repair_Homo sapiens_hsa034100.77108467
93RNA transport_Homo sapiens_hsa030130.76101469
94ABC transporters_Homo sapiens_hsa020100.75318335
95Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73549668
96Insulin secretion_Homo sapiens_hsa049110.72530435
97Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72105845
98Chemical carcinogenesis_Homo sapiens_hsa052040.71514401
99Serotonergic synapse_Homo sapiens_hsa047260.70236487
100Protein digestion and absorption_Homo sapiens_hsa049740.66672704
101Lysine degradation_Homo sapiens_hsa003100.66325605
102Bile secretion_Homo sapiens_hsa049760.65729194
103Biosynthesis of amino acids_Homo sapiens_hsa012300.65511735
104Thyroid hormone synthesis_Homo sapiens_hsa049180.64521830
105Legionellosis_Homo sapiens_hsa051340.64258957
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63769990
107Inositol phosphate metabolism_Homo sapiens_hsa005620.63569364
108Folate biosynthesis_Homo sapiens_hsa007900.62725363
109Dopaminergic synapse_Homo sapiens_hsa047280.62241126
110Estrogen signaling pathway_Homo sapiens_hsa049150.61744132
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57810648
112Calcium signaling pathway_Homo sapiens_hsa040200.57778365
113Tight junction_Homo sapiens_hsa045300.57215678
114Regulation of autophagy_Homo sapiens_hsa041400.57147184
115cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55562935
116Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.55217749
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54544961
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.52290444
119Long-term potentiation_Homo sapiens_hsa047200.51703227
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51443396
121Proteasome_Homo sapiens_hsa030500.51362494
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51347027
123Hippo signaling pathway_Homo sapiens_hsa043900.51020558
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50084323
125Spliceosome_Homo sapiens_hsa030400.49275241
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.48886948
127Fatty acid elongation_Homo sapiens_hsa000620.48303036
128Axon guidance_Homo sapiens_hsa043600.48233334
129Sulfur metabolism_Homo sapiens_hsa009200.48191387
130Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47595120
131Central carbon metabolism in cancer_Homo sapiens_hsa052300.46196373
132Pancreatic secretion_Homo sapiens_hsa049720.45806180
133Renin-angiotensin system_Homo sapiens_hsa046140.44689134
134Taste transduction_Homo sapiens_hsa047420.44106997
135Systemic lupus erythematosus_Homo sapiens_hsa053220.43686975
136Metabolic pathways_Homo sapiens_hsa011000.42071350
137Salivary secretion_Homo sapiens_hsa049700.41110682
138Endocytosis_Homo sapiens_hsa041440.39061548
139VEGF signaling pathway_Homo sapiens_hsa043700.35825301
140Synaptic vesicle cycle_Homo sapiens_hsa047210.34988613
141Pentose and glucuronate interconversions_Homo sapiens_hsa000400.32140719
142Basal cell carcinoma_Homo sapiens_hsa052170.32060626
143Pyrimidine metabolism_Homo sapiens_hsa002400.30734170
144cAMP signaling pathway_Homo sapiens_hsa040240.28170468
145Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.27110038
146Gastric acid secretion_Homo sapiens_hsa049710.26812038
147Vascular smooth muscle contraction_Homo sapiens_hsa042700.24932876
148Wnt signaling pathway_Homo sapiens_hsa043100.23670074
149AMPK signaling pathway_Homo sapiens_hsa041520.22172118
150Retinol metabolism_Homo sapiens_hsa008300.19446657
151Circadian entrainment_Homo sapiens_hsa047130.18486678
152Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.16790921
153Vitamin digestion and absorption_Homo sapiens_hsa049770.15699027
154Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.13233377
155Toxoplasmosis_Homo sapiens_hsa051450.12761077
156B cell receptor signaling pathway_Homo sapiens_hsa046620.12651022
157Steroid hormone biosynthesis_Homo sapiens_hsa001400.12501466
158Cell cycle_Homo sapiens_hsa041100.10905175
159Alcoholism_Homo sapiens_hsa050340.10609034
160Sphingolipid metabolism_Homo sapiens_hsa006000.10210726
161Salmonella infection_Homo sapiens_hsa051320.09507020

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