| 1 | Birth length less than 3rd percentile (HP:0003561) | 5.19496126 |
| 2 | Ependymoma (HP:0002888) | 4.31662539 |
| 3 | Colon cancer (HP:0003003) | 4.00837181 |
| 4 | Agnosia (HP:0010524) | 3.83921590 |
| 5 | Breast hypoplasia (HP:0003187) | 3.70434222 |
| 6 | Medulloblastoma (HP:0002885) | 3.69936046 |
| 7 | Oral leukoplakia (HP:0002745) | 3.63065210 |
| 8 | Microvesicular hepatic steatosis (HP:0001414) | 3.54751741 |
| 9 | Reticulocytopenia (HP:0001896) | 3.50639024 |
| 10 | Selective tooth agenesis (HP:0001592) | 3.46813486 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.42671681 |
| 12 | Increased serum pyruvate (HP:0003542) | 3.40680455 |
| 13 | Degeneration of anterior horn cells (HP:0002398) | 3.38952635 |
| 14 | Abnormality of the anterior horn cell (HP:0006802) | 3.38952635 |
| 15 | Rhabdomyosarcoma (HP:0002859) | 3.37030080 |
| 16 | Aplastic anemia (HP:0001915) | 3.31703050 |
| 17 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.31415873 |
| 18 | Cerebral hypomyelination (HP:0006808) | 3.25264498 |
| 19 | Chromsome breakage (HP:0040012) | 3.21394710 |
| 20 | Abnormality of the labia minora (HP:0012880) | 3.20449391 |
| 21 | Abnormal number of erythroid precursors (HP:0012131) | 3.18698204 |
| 22 | Increased mean platelet volume (HP:0011877) | 3.15650157 |
| 23 | Impulsivity (HP:0100710) | 3.14377376 |
| 24 | Abnormality of glycolysis (HP:0004366) | 3.12718561 |
| 25 | Embryonal renal neoplasm (HP:0011794) | 3.09928041 |
| 26 | Abnormality of chromosome stability (HP:0003220) | 3.01239690 |
| 27 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.99505372 |
| 28 | Basal cell carcinoma (HP:0002671) | 2.97119757 |
| 29 | Abnormality of the astrocytes (HP:0100707) | 2.88546345 |
| 30 | Astrocytoma (HP:0009592) | 2.88546345 |
| 31 | Patellar aplasia (HP:0006443) | 2.86574274 |
| 32 | Abnormality of methionine metabolism (HP:0010901) | 2.80988914 |
| 33 | Abnormal platelet volume (HP:0011876) | 2.79837613 |
| 34 | Abnormality of the preputium (HP:0100587) | 2.79452181 |
| 35 | Carpal bone hypoplasia (HP:0001498) | 2.75651335 |
| 36 | Meckel diverticulum (HP:0002245) | 2.75611227 |
| 37 | Myelodysplasia (HP:0002863) | 2.72742418 |
| 38 | Rough bone trabeculation (HP:0100670) | 2.71966296 |
| 39 | Absent thumb (HP:0009777) | 2.70467153 |
| 40 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.66641327 |
| 41 | Abnormality of the ileum (HP:0001549) | 2.63741281 |
| 42 | Multiple enchondromatosis (HP:0005701) | 2.63308876 |
| 43 | Premature ovarian failure (HP:0008209) | 2.62976512 |
| 44 | Amaurosis fugax (HP:0100576) | 2.61521539 |
| 45 | Macrocytic anemia (HP:0001972) | 2.61132574 |
| 46 | Neoplasm of the pancreas (HP:0002894) | 2.59391552 |
| 47 | Microretrognathia (HP:0000308) | 2.58696092 |
| 48 | Combined immunodeficiency (HP:0005387) | 2.56709648 |
| 49 | Cortical dysplasia (HP:0002539) | 2.56456783 |
| 50 | Glioma (HP:0009733) | 2.55661480 |
| 51 | Short middle phalanx of the 5th finger (HP:0004220) | 2.52586212 |
| 52 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.51234372 |
| 53 | Reduced antithrombin III activity (HP:0001976) | 2.51150005 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.50888397 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 2.50888397 |
| 56 | Hyperalaninemia (HP:0003348) | 2.50888397 |
| 57 | Biliary tract neoplasm (HP:0100574) | 2.50106745 |
| 58 | Type I transferrin isoform profile (HP:0003642) | 2.48882060 |
| 59 | Squamous cell carcinoma (HP:0002860) | 2.48824825 |
| 60 | Proximal placement of thumb (HP:0009623) | 2.45863635 |
| 61 | Increased hepatocellular lipid droplets (HP:0006565) | 2.44569205 |
| 62 | Neoplasm of striated muscle (HP:0009728) | 2.43744992 |
| 63 | Premature graying of hair (HP:0002216) | 2.40514759 |
| 64 | Deviation of the thumb (HP:0009603) | 2.40441556 |
| 65 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.39434797 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.39434797 |
| 67 | Abnormal protein glycosylation (HP:0012346) | 2.39434797 |
| 68 | Abnormal glycosylation (HP:0012345) | 2.39434797 |
| 69 | Prolonged bleeding time (HP:0003010) | 2.38097031 |
| 70 | Increased serum lactate (HP:0002151) | 2.37748538 |
| 71 | Thrombocytosis (HP:0001894) | 2.37556994 |
| 72 | Duodenal stenosis (HP:0100867) | 2.37161329 |
| 73 | Small intestinal stenosis (HP:0012848) | 2.37161329 |
| 74 | Supernumerary spleens (HP:0009799) | 2.33084995 |
| 75 | Absent radius (HP:0003974) | 2.30325242 |
| 76 | B lymphocytopenia (HP:0010976) | 2.27469829 |
| 77 | Megaloblastic anemia (HP:0001889) | 2.26587315 |
| 78 | 11 pairs of ribs (HP:0000878) | 2.26054819 |
| 79 | Pallor (HP:0000980) | 2.25964992 |
| 80 | Sloping forehead (HP:0000340) | 2.25928615 |
| 81 | Cafe-au-lait spot (HP:0000957) | 2.24669097 |
| 82 | Secondary amenorrhea (HP:0000869) | 2.24250163 |
| 83 | Trismus (HP:0000211) | 2.24005639 |
| 84 | Severe combined immunodeficiency (HP:0004430) | 2.21063045 |
| 85 | Bone marrow hypocellularity (HP:0005528) | 2.19622273 |
| 86 | Acute myeloid leukemia (HP:0004808) | 2.19134559 |
| 87 | Acute encephalopathy (HP:0006846) | 2.19079069 |
| 88 | Lipid accumulation in hepatocytes (HP:0006561) | 2.17761669 |
| 89 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.17366654 |
| 90 | Adenoma sebaceum (HP:0009720) | 2.16949434 |
| 91 | Angiofibromas (HP:0010615) | 2.16949434 |
| 92 | Progressive external ophthalmoplegia (HP:0000590) | 2.16665503 |
| 93 | Neoplasm of the colon (HP:0100273) | 2.16518354 |
| 94 | Facial hemangioma (HP:0000329) | 2.16365941 |
| 95 | Neoplasm of the oral cavity (HP:0100649) | 2.16311064 |
| 96 | Atresia of the external auditory canal (HP:0000413) | 2.15953859 |
| 97 | Prominent nose (HP:0000448) | 2.15670504 |
| 98 | Abnormality of serum amino acid levels (HP:0003112) | 2.14696522 |
| 99 | Horseshoe kidney (HP:0000085) | 2.14643973 |
| 100 | Cutaneous melanoma (HP:0012056) | 2.14560338 |
| 101 | Panhypogammaglobulinemia (HP:0003139) | 2.11887531 |
| 102 | Missing ribs (HP:0000921) | 2.10689473 |
| 103 | Cellular immunodeficiency (HP:0005374) | 2.10373069 |
| 104 | IgM deficiency (HP:0002850) | 2.10028634 |
| 105 | Entropion (HP:0000621) | 2.08479680 |
| 106 | Aplasia involving forearm bones (HP:0009822) | 2.07388100 |
| 107 | Absent forearm bone (HP:0003953) | 2.07388100 |
| 108 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.06990582 |
| 109 | Abnormal lung lobation (HP:0002101) | 2.06409072 |
| 110 | Spastic diplegia (HP:0001264) | 2.05772734 |
| 111 | Volvulus (HP:0002580) | 2.05036588 |
| 112 | Acanthocytosis (HP:0001927) | 2.04805540 |
| 113 | CNS hypomyelination (HP:0003429) | 2.03111260 |
| 114 | Pelvic girdle muscle weakness (HP:0003749) | 2.02592251 |
| 115 | Progressive muscle weakness (HP:0003323) | 2.02351062 |
| 116 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.01469749 |
| 117 | Abnormality of the duodenum (HP:0002246) | 2.00518774 |
| 118 | Personality changes (HP:0000751) | 1.99528071 |
| 119 | Ectopic kidney (HP:0000086) | 1.98484877 |
| 120 | Petechiae (HP:0000967) | 1.98182187 |
| 121 | Increased CSF lactate (HP:0002490) | 1.97367784 |
| 122 | Neoplasm of the rectum (HP:0100743) | 1.97210675 |
| 123 | Increased nuchal translucency (HP:0010880) | 1.96029933 |
| 124 | Clubbing of toes (HP:0100760) | 1.94263464 |
| 125 | Slender long bone (HP:0003100) | 1.92179895 |
| 126 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.90918438 |
| 127 | Sparse lateral eyebrow (HP:0005338) | 1.90907239 |
| 128 | Erythroderma (HP:0001019) | 1.90833150 |
| 129 | Abnormal trabecular bone morphology (HP:0100671) | 1.89931357 |
| 130 | Abnormal hair whorl (HP:0010721) | 1.89351274 |
| 131 | Tracheoesophageal fistula (HP:0002575) | 1.89338492 |
| 132 | Abnormality of the pons (HP:0007361) | 1.89013988 |
| 133 | Lymphoma (HP:0002665) | 1.88391561 |
| 134 | Poikiloderma (HP:0001029) | 1.87580736 |
| 135 | Shoulder girdle muscle weakness (HP:0003547) | 1.87524134 |
| 136 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.86434244 |
| 137 | Cerebral edema (HP:0002181) | 1.86224894 |
| 138 | Postnatal microcephaly (HP:0005484) | 1.85664335 |
| 139 | Abnormality of the carotid arteries (HP:0005344) | 1.85394901 |
| 140 | Hypoplasia of the pons (HP:0012110) | 1.85075194 |
| 141 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.84579583 |
| 142 | Pancytopenia (HP:0001876) | 1.83898623 |
| 143 | Dyschromatopsia (HP:0007641) | 1.83224897 |
| 144 | Glossoptosis (HP:0000162) | 1.81888588 |
| 145 | Abnormal number of incisors (HP:0011064) | 1.81002312 |
| 146 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.80570042 |
| 147 | Respiratory difficulties (HP:0002880) | 1.80370782 |
| 148 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.80315491 |
| 149 | Freckling (HP:0001480) | 1.79613318 |
| 150 | Lactic acidosis (HP:0003128) | 1.78753209 |
| 151 | Ovarian neoplasm (HP:0100615) | 1.78600273 |
| 152 | Acute necrotizing encephalopathy (HP:0006965) | 1.76743331 |
| 153 | Abnormality of B cell number (HP:0010975) | 1.75701004 |
| 154 | Hypoplastic pelvis (HP:0008839) | 1.74347720 |
| 155 | Autoamputation (HP:0001218) | 1.73176383 |
| 156 | Embryonal neoplasm (HP:0002898) | 1.70861150 |
| 157 | Neoplasm of the small intestine (HP:0100833) | 1.68194683 |
| 158 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.67978852 |
TTC27 
