TTC38

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.21377480
2L-phenylalanine catabolic process (GO:0006559)7.21377480
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.89733138
4L-phenylalanine metabolic process (GO:0006558)6.89733138
5epoxygenase P450 pathway (GO:0019373)6.55704392
6aromatic amino acid family catabolic process (GO:0009074)6.54675092
7exogenous drug catabolic process (GO:0042738)6.20575658
8indole-containing compound catabolic process (GO:0042436)5.96874327
9indolalkylamine catabolic process (GO:0046218)5.96874327
10tryptophan catabolic process (GO:0006569)5.96874327
11triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.95408254
12kynurenine metabolic process (GO:0070189)5.72134865
13tryptophan metabolic process (GO:0006568)5.63327084
14bile acid biosynthetic process (GO:0006699)5.56519316
15glyoxylate metabolic process (GO:0046487)5.50879857
16sulfur amino acid catabolic process (GO:0000098)5.44766013
17omega-hydroxylase P450 pathway (GO:0097267)5.40014580
18alpha-linolenic acid metabolic process (GO:0036109)5.34886192
19urea cycle (GO:0000050)5.34591043
20urea metabolic process (GO:0019627)5.34591043
21high-density lipoprotein particle remodeling (GO:0034375)5.28940215
22cysteine metabolic process (GO:0006534)5.20062949
23negative regulation of fibrinolysis (GO:0051918)5.04415918
24protein carboxylation (GO:0018214)4.95818711
25peptidyl-glutamic acid carboxylation (GO:0017187)4.95818711
26regulation of fibrinolysis (GO:0051917)4.94881465
27fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.92100434
28nitrogen cycle metabolic process (GO:0071941)4.91934840
29complement activation, alternative pathway (GO:0006957)4.90948228
30bile acid metabolic process (GO:0008206)4.87832119
31serine family amino acid catabolic process (GO:0009071)4.86437251
32regulation of protein activation cascade (GO:2000257)4.80493960
33aromatic amino acid family metabolic process (GO:0009072)4.74571592
34homocysteine metabolic process (GO:0050667)4.72253461
35regulation of cholesterol esterification (GO:0010872)4.71684619
36regulation of triglyceride catabolic process (GO:0010896)4.66239866
37reverse cholesterol transport (GO:0043691)4.65557179
38amino-acid betaine metabolic process (GO:0006577)4.62864832
39lysine metabolic process (GO:0006553)4.62048027
40lysine catabolic process (GO:0006554)4.62048027
41protein-lipid complex remodeling (GO:0034368)4.56130519
42macromolecular complex remodeling (GO:0034367)4.56130519
43plasma lipoprotein particle remodeling (GO:0034369)4.56130519
44tyrosine metabolic process (GO:0006570)4.54189776
45alpha-amino acid catabolic process (GO:1901606)4.49471831
46regulation of complement activation (GO:0030449)4.48200610
47cellular ketone body metabolic process (GO:0046950)4.48119387
48drug metabolic process (GO:0017144)4.46842723
49acylglycerol homeostasis (GO:0055090)4.41750875
50triglyceride homeostasis (GO:0070328)4.41750875
51phospholipid efflux (GO:0033700)4.38608827
52heme transport (GO:0015886)4.32252328
53bile acid and bile salt transport (GO:0015721)4.30468601
54negative regulation of sterol transport (GO:0032372)4.29329960
55negative regulation of cholesterol transport (GO:0032375)4.29329960
56indolalkylamine metabolic process (GO:0006586)4.23307696
57cellular glucuronidation (GO:0052695)4.22930292
58cellular amino acid catabolic process (GO:0009063)4.19317565
59cellular biogenic amine catabolic process (GO:0042402)4.18828509
60amine catabolic process (GO:0009310)4.18828509
61purine ribonucleotide transport (GO:0015868)4.15612741
62benzene-containing compound metabolic process (GO:0042537)4.14149762
63coenzyme catabolic process (GO:0009109)4.13992481
64plasma lipoprotein particle clearance (GO:0034381)4.09313266
65ethanol oxidation (GO:0006069)4.09083225
66cholesterol efflux (GO:0033344)4.01928506
67imidazole-containing compound metabolic process (GO:0052803)3.98158371
68glycine metabolic process (GO:0006544)3.96273238
69cellular modified amino acid catabolic process (GO:0042219)3.95751089
70low-density lipoprotein particle remodeling (GO:0034374)3.91720419
71short-chain fatty acid metabolic process (GO:0046459)3.91192482
72acute-phase response (GO:0006953)3.89954512
73glutamate metabolic process (GO:0006536)3.87869824
74protein activation cascade (GO:0072376)3.87824983
75phospholipid homeostasis (GO:0055091)3.86864124
76serine family amino acid metabolic process (GO:0009069)3.86520106
77complement activation, classical pathway (GO:0006958)3.86496090
78ketone body metabolic process (GO:1902224)3.86206228
79regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.85983137
80response to nitrosative stress (GO:0051409)3.82393870
81drug catabolic process (GO:0042737)3.81939500
82complement activation (GO:0006956)3.80641063
83organic acid catabolic process (GO:0016054)3.80431972
84carboxylic acid catabolic process (GO:0046395)3.80431972
85plasma lipoprotein particle assembly (GO:0034377)3.80291155
86uronic acid metabolic process (GO:0006063)3.77891320
87glucuronate metabolic process (GO:0019585)3.77891320
88arginine metabolic process (GO:0006525)3.75663279
89fatty acid beta-oxidation (GO:0006635)3.73933561
90regulation of bile acid biosynthetic process (GO:0070857)3.72430572
91aldehyde catabolic process (GO:0046185)3.69616484
92fatty acid oxidation (GO:0019395)3.69562538
93negative regulation of lipase activity (GO:0060192)3.67078257
94monocarboxylic acid catabolic process (GO:0072329)3.66028368
95fibrinolysis (GO:0042730)3.65740820
96ethanol metabolic process (GO:0006067)3.65171164
97cholesterol homeostasis (GO:0042632)3.64636549
98positive regulation of triglyceride lipase activity (GO:0061365)3.64493897
99positive regulation of lipoprotein lipase activity (GO:0051006)3.64493897
100NAD biosynthetic process (GO:0009435)3.63326854
101oxidative demethylation (GO:0070989)3.62973446
102lipid oxidation (GO:0034440)3.62401307
103acetyl-CoA metabolic process (GO:0006084)3.60457054
104blood coagulation, intrinsic pathway (GO:0007597)3.59751711
105dicarboxylic acid biosynthetic process (GO:0043650)3.59681598
106positive regulation of lipid catabolic process (GO:0050996)3.59233489
107fatty acid catabolic process (GO:0009062)3.58947620
108fat-soluble vitamin biosynthetic process (GO:0042362)3.58754357
109sterol homeostasis (GO:0055092)3.58072650
110serine family amino acid biosynthetic process (GO:0009070)3.57792758
111valine metabolic process (GO:0006573)3.57789840
1122-oxoglutarate metabolic process (GO:0006103)3.57219028
113regulation of humoral immune response (GO:0002920)3.57077772
114very-low-density lipoprotein particle assembly (GO:0034379)3.55964167
115cofactor catabolic process (GO:0051187)3.55529524
116intestinal absorption (GO:0050892)3.53235579
117hormone catabolic process (GO:0042447)3.47757023
118alkaloid metabolic process (GO:0009820)3.45479667
119negative regulation of blood coagulation (GO:0030195)3.41629666
120negative regulation of hemostasis (GO:1900047)3.41629666
121regulation of plasminogen activation (GO:0010755)3.41614932
122regulation of lipoprotein particle clearance (GO:0010984)3.37973053
123protein-lipid complex assembly (GO:0065005)3.37946238
124cytolysis (GO:0019835)3.37581574
125angiotensin maturation (GO:0002003)3.31602199
126plasma lipoprotein particle organization (GO:0071827)3.31539220
127positive regulation of fatty acid biosynthetic process (GO:0045723)3.29908895
128killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.24407923
129disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.24407923
130drug transport (GO:0015893)3.23983949
131intestinal cholesterol absorption (GO:0030299)3.19133232
132purine nucleotide transport (GO:0015865)3.17585764
133antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.15277631
134negative regulation of protein activation cascade (GO:2000258)3.13267285
135diacylglycerol metabolic process (GO:0046339)3.12793483
136nucleotide transmembrane transport (GO:1901679)3.12661177
137opsonization (GO:0008228)3.12562781
138protein-lipid complex subunit organization (GO:0071825)3.12298469
139negative regulation of type 2 immune response (GO:0002829)3.11429616
140negative regulation of coagulation (GO:0050819)3.11093052
141flavonoid metabolic process (GO:0009812)3.08959579
142lipoprotein metabolic process (GO:0042157)3.05965268
143NADH metabolic process (GO:0006734)3.04020437
144phenylpropanoid metabolic process (GO:0009698)3.03836255
145nucleoside transmembrane transport (GO:1901642)3.02823765
146killing of cells of other organism (GO:0031640)3.00804033
147disruption of cells of other organism (GO:0044364)3.00804033
148antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.97810331

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.98572246
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.86657904
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.68048656
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.25695447
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.10744061
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.07391342
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.91199469
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.87603028
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.77801918
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.63918059
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.18798947
12VDR_21846776_ChIP-Seq_THP-1_Human2.04329094
13TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.00468302
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.2437127
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96338048
16ZNF263_19887448_ChIP-Seq_K562_Human1.68885458
17GATA1_22025678_ChIP-Seq_K562_Human1.68219349
18TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63905787
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.63410450
20FOXA2_19822575_ChIP-Seq_HepG2_Human1.58515718
21BCL6_27268052_Chip-Seq_Bcells_Human1.56983875
22IRF8_22096565_ChIP-ChIP_GC-B_Human1.52933522
23IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.51013834
24CLOCK_20551151_ChIP-Seq_293T_Human1.48639441
25IRF8_21731497_ChIP-ChIP_J774_Mouse1.45282072
26BCOR_27268052_Chip-Seq_Bcells_Human1.40303549
27ELK3_25401928_ChIP-Seq_HUVEC_Human1.38829752
28HTT_18923047_ChIP-ChIP_STHdh_Human1.34946023
29HNF4A_19822575_ChIP-Seq_HepG2_Human1.34892115
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.34510020
31CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.32737279
32MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.32118100
33CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30477525
34P68_20966046_ChIP-Seq_HELA_Human1.27861685
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.26841016
36SA1_27219007_Chip-Seq_Bcells_Human1.26325356
37IRF8_27001747_Chip-Seq_BMDM_Mouse1.23531228
38VDR_24763502_ChIP-Seq_THP-1_Human1.23015129
39E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.22085294
40RACK7_27058665_Chip-Seq_MCF-7_Human1.18332995
41TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16935419
42TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16530838
43SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.15210442
44SOX2_27498859_Chip-Seq_STOMACH_Mouse1.15135060
45P300_27268052_Chip-Seq_Bcells_Human1.13789214
46LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.13002876
47GATA1_22383799_ChIP-Seq_G1ME_Mouse1.12028943
48SRY_22984422_ChIP-ChIP_TESTIS_Rat1.10312985
49CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07729082
50RXRA_24833708_ChIP-Seq_LIVER_Mouse1.07451180
51STAT4_19710469_ChIP-ChIP_TH1__Mouse1.07301084
52ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.07107475
53RUNX1_22412390_ChIP-Seq_EML_Mouse1.06826515
54SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05812224
55GATA2_22383799_ChIP-Seq_G1ME_Mouse1.05128342
56PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04037469
57E2F1_20622854_ChIP-Seq_HELA_Human1.03779591
58PHF8_20622854_ChIP-Seq_HELA_Human1.03682887
59ELF1_20517297_ChIP-Seq_JURKAT_Human1.03478670
60MAF_26560356_Chip-Seq_TH1_Human1.03281296
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.03005316
62SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.00975711
63TET1_21451524_ChIP-Seq_MESCs_Mouse1.00926203
64PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.99091113
65JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.99009286
66CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97618483
67CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97603058
68GATA4_25053715_ChIP-Seq_YYC3_Human0.96436822
69KDM2B_26808549_Chip-Seq_SUP-B15_Human0.94973543
70SMC4_20622854_ChIP-Seq_HELA_Human0.94782348
71RARG_19884340_ChIP-ChIP_MEFs_Mouse0.94710515
72SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94401674
73SA1_27219007_Chip-Seq_ERYTHROID_Human0.92591344
74Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.92306675
75KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.91531122
76KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.91456599
77P63_26484246_Chip-Seq_KERATINOCYTES_Human0.91064861
78SPI1_20517297_ChIP-Seq_HL60_Human0.90051976
79PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89568981
80CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.89514455
81TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89257962
82TCF7_22412390_ChIP-Seq_EML_Mouse0.87940347
83UTX_26944678_Chip-Seq_JUKART_Human0.87700123
84SOX2_21211035_ChIP-Seq_LN229_Human0.87565366
85SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87438766
86PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83182357
87BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82709677
88ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.82394923
89KAP1_22055183_ChIP-Seq_ESCs_Mouse0.78171666
90CDX2_20551321_ChIP-Seq_CACO-2_Human0.77527953
91AUTS2_25519132_ChIP-Seq_293T-REX_Human0.76112688
92AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.75587329
93RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.73733731
94BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.73688669
95ESR1_20079471_ChIP-ChIP_T-47D_Human0.73315711
96CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.73223411
97ESR2_21235772_ChIP-Seq_MCF-7_Human0.72533467
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.70695817
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.70387325
100NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.69927943
101NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67681836
102NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67681836
103CEBPB_22108803_ChIP-Seq_LS180_Human0.67513494
104FOXA1_25552417_ChIP-Seq_VCAP_Human0.66118928
105FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.65668599
106SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.65609021
107ESR1_21235772_ChIP-Seq_MCF-7_Human0.65002262
108* AR_20517297_ChIP-Seq_VCAP_Human0.64115921
109FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.62902704
110RARA_24833708_ChIP-Seq_LIVER_Mouse0.61548438
111RAD21_21589869_ChIP-Seq_MESCs_Mouse0.61399813
112SALL4_18804426_ChIP-ChIP_XEN_Mouse0.59696984
113FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.59370774
114PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.59204890
115IRF1_19129219_ChIP-ChIP_H3396_Human0.58551975
116PPAR_26484153_Chip-Seq_NCI-H1993_Human0.58251677
117STAT1_17558387_ChIP-Seq_HELA_Human0.56923021
118PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.55258143
119GATA2_21666600_ChIP-Seq_HMVEC_Human0.54930698
120LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.54549369
121GATA1_19941827_ChIP-Seq_MEL_Mouse0.54448960
122TAF15_26573619_Chip-Seq_HEK293_Human0.53924164
123* RARB_24833708_ChIP-Seq_LIVER_Mouse0.53061621
124GATA2_19941826_ChIP-Seq_K562_Human0.52983833
125NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.52135446
126PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.51621795
127GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.51602078
128GATA6_25053715_ChIP-Seq_YYC3_Human0.50308611
129SOX2_20726797_ChIP-Seq_SW620_Human0.49896319
130FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.48959894
131BCAT_22108803_ChIP-Seq_LS180_Human0.48605656
132ESET_19884257_ChIP-Seq_ESCs_Mouse0.48489902
133CBP_21632823_ChIP-Seq_H3396_Human0.48023992
134CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.47770999
135EGR1_19032775_ChIP-ChIP_M12_Human0.47652333
136CDX2_22108803_ChIP-Seq_LS180_Human0.47623583
137SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.45978276
138MYC_19915707_ChIP-ChIP_AK7_Human0.45861874
139SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.45563572
140* LXR_22292898_ChIP-Seq_THP-1_Human0.45328457
141EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.44375719
142FOXO3_23340844_ChIP-Seq_DLD1_Human0.43947254
143PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.43668711
144GATA1_19941826_ChIP-Seq_K562_Human0.43519431
145GATA3_24758297_ChIP-Seq_MCF-7_Human0.43149786
146ESR1_15608294_ChIP-ChIP_MCF-7_Human0.42099514
147NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.41789098
148ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.41337930
149SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41298830
150TBX20_22328084_ChIP-Seq_HEART_Mouse0.41217754
151TBX20_22080862_ChIP-Seq_HEART_Mouse0.41217754
152P53_21459846_ChIP-Seq_SAOS-2_Human0.41090168
153ERG_20517297_ChIP-Seq_VCAP_Human0.40573866
154RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.39554824

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system7.80731040
2MP0005360_urolithiasis7.26028018
3MP0005085_abnormal_gallbladder_physiolo6.13245468
4MP0005365_abnormal_bile_salt6.05929330
5MP0008875_abnormal_xenobiotic_pharmacok5.03757143
6MP0003806_abnormal_nucleotide_metabolis3.79260220
7MP0003252_abnormal_bile_duct3.75983425
8MP0010329_abnormal_lipoprotein_level3.51102998
9MP0009840_abnormal_foam_cell3.07608532
10MP0005083_abnormal_biliary_tract2.85266132
11MP0003195_calcinosis2.75947300
12MP0005332_abnormal_amino_acid2.75011726
13MP0001666_abnormal_nutrient_absorption2.68881454
14MP0003191_abnormal_cellular_cholesterol2.48104741
15MP0004019_abnormal_vitamin_homeostasis2.21497780
16MP0002138_abnormal_hepatobiliary_system2.12289285
17MP0002118_abnormal_lipid_homeostasis2.11468480
18MP0000609_abnormal_liver_physiology2.11163461
19MP0003303_peritoneal_inflammation2.08482658
20MP0003868_abnormal_feces_composition1.97943554
21MP0005319_abnormal_enzyme/_coenzyme1.84232083
22MP0001764_abnormal_homeostasis1.80082957
23MP0003183_abnormal_peptide_metabolism1.73235857
24MP0010155_abnormal_intestine_physiology1.68509127
25MP0005451_abnormal_body_composition1.61115391
26MP0005584_abnormal_enzyme/coenzyme_acti1.57918643
27MP0009697_abnormal_copulation1.57622835
28MP0005025_abnormal_response_to1.49463643
29MP0003186_abnormal_redox_activity1.46227728
30MP0009643_abnormal_urine_homeostasis1.42369379
31MP0005670_abnormal_white_adipose1.40094605
32MP0005671_abnormal_response_to1.28910230
33MP0001835_abnormal_antigen_presentation1.28673846
34MP0002419_abnormal_innate_immunity1.23638898
35MP0000858_altered_metastatic_potential1.23206992
36MP0003011_delayed_dark_adaptation1.20238699
37MP0003656_abnormal_erythrocyte_physiolo1.19369869
38MP0009333_abnormal_splenocyte_physiolog1.19330239
39MP0005647_abnormal_sex_gland1.16766635
40MP0009764_decreased_sensitivity_to1.16564884
41MP0001873_stomach_inflammation1.16190155
42MP0000685_abnormal_immune_system1.15705359
43MP0001800_abnormal_humoral_immune1.15405473
44MP0005000_abnormal_immune_tolerance1.15213211
45MP0000598_abnormal_liver_morphology1.11326072
46MP0002876_abnormal_thyroid_physiology1.07312836
47MP0001533_abnormal_skeleton_physiology1.05145321
48MP0002254_reproductive_system_inflammat1.04116041
49MP0009763_increased_sensitivity_to1.02629054
50MP0005636_abnormal_mineral_homeostasis1.02245671
51MP0002723_abnormal_immune_serum1.01869280
52MP0001790_abnormal_immune_system0.99879422
53MP0005387_immune_system_phenotype0.99879422
54MP0010368_abnormal_lymphatic_system0.98644308
55MP0004130_abnormal_muscle_cell0.98276292
56MP0008469_abnormal_protein_level0.96235955
57MP0001663_abnormal_digestive_system0.92747280
58MP0005084_abnormal_gallbladder_morpholo0.91385972
59MP0006036_abnormal_mitochondrial_physio0.90392561
60MP0003705_abnormal_hypodermis_morpholog0.89998615
61MP0009642_abnormal_blood_homeostasis0.89978183
62MP0002971_abnormal_brown_adipose0.88708626
63MP0001851_eye_inflammation0.87911726
64MP0005408_hypopigmentation0.86172909
65MP0003724_increased_susceptibility_to0.85497579
66MP0000490_abnormal_crypts_of0.85293744
67MP0002332_abnormal_exercise_endurance0.84850640
68MP0002078_abnormal_glucose_homeostasis0.83399646
69MP0005334_abnormal_fat_pad0.82609014
70MP0004782_abnormal_surfactant_physiolog0.82431476
71MP0002452_abnormal_antigen_presenting0.82024484
72MP0002148_abnormal_hypersensitivity_rea0.81421159
73MP0005220_abnormal_exocrine_pancreas0.80960997
74MP0009765_abnormal_xenobiotic_induced0.80754867
75MP0003866_abnormal_defecation0.79828700
76MP0001819_abnormal_immune_cell0.78642520
77MP0002420_abnormal_adaptive_immunity0.78013128
78MP0000604_amyloidosis0.77601388
79MP0005376_homeostasis/metabolism_phenot0.77426545
80MP0005381_digestive/alimentary_phenotyp0.77391853
81MP0005535_abnormal_body_temperature0.76886537
82MP0003879_abnormal_hair_cell0.76776998
83MP0002837_dystrophic_cardiac_calcinosis0.75016583
84MP0002166_altered_tumor_susceptibility0.69332615
85MP0005666_abnormal_adipose_tissue0.68324370
86MP0001756_abnormal_urination0.68188418
87MP0003763_abnormal_thymus_physiology0.67605093
88MP0003690_abnormal_glial_cell0.63931241
89MP0000477_abnormal_intestine_morphology0.63651115
90MP0005266_abnormal_metabolism0.63646571
91MP0001545_abnormal_hematopoietic_system0.63582757
92MP0005397_hematopoietic_system_phenotyp0.63582757
93MP0005464_abnormal_platelet_physiology0.63541483
94MP0004947_skin_inflammation0.61962297
95MP0002998_abnormal_bone_remodeling0.60508480
96MP0009278_abnormal_bone_marrow0.59980312
97MP0005448_abnormal_energy_balance0.59812642
98MP0002136_abnormal_kidney_physiology0.59733251
99MP0002405_respiratory_system_inflammati0.57984837
100MP0000716_abnormal_immune_system0.57961138
101MP0001661_extended_life_span0.57944815
102MP0004381_abnormal_hair_follicle0.56066927
103MP0002132_abnormal_respiratory_system0.52632982
104MP0004043_abnormal_pH_regulation0.51718696
105MP0003436_decreased_susceptibility_to0.50411811
106MP0003638_abnormal_response/metabolism_0.48682423
107MP0001853_heart_inflammation0.48086570
108MP0005058_abnormal_lysosome_morphology0.47584658
109MP0003953_abnormal_hormone_level0.47535111
110MP0009115_abnormal_fat_cell0.47232748
111MP0000639_abnormal_adrenal_gland0.46372604
112MP0002928_abnormal_bile_duct0.45230773
113MP0000230_abnormal_systemic_arterial0.44811341
114MP0001845_abnormal_inflammatory_respons0.43787266
115MP0004264_abnormal_extraembryonic_tissu0.42108178
116MP0005395_other_phenotype0.40902609
117MP0008873_increased_physiological_sensi0.39997360
118MP0006035_abnormal_mitochondrial_morpho0.39984000
119MP0000566_synostosis0.39241230
120MP0006082_CNS_inflammation0.38797578
121MP0009053_abnormal_anal_canal0.37608198
122MP0000249_abnormal_blood_vessel0.37339508
123MP0002970_abnormal_white_adipose0.36812485
124MP0005166_decreased_susceptibility_to0.36708997
125MP0008874_decreased_physiological_sensi0.35281594
126MP0004147_increased_porphyrin_level0.35138890
127MP0000579_abnormal_nail_morphology0.34956748
128MP0008872_abnormal_physiological_respon0.34329701
129MP0003075_altered_response_to0.33879991
130MP0001765_abnormal_ion_homeostasis0.33169823
131MP0009785_altered_susceptibility_to0.32276253
132MP0005075_abnormal_melanosome_morpholog0.32232367
133MP0005248_abnormal_Harderian_gland0.32129975
134MP0002822_catalepsy0.32021281
135MP0002168_other_aberrant_phenotype0.31224364
136MP0001881_abnormal_mammary_gland0.30945749
137MP0003718_maternal_effect0.29962668
138MP0003300_gastrointestinal_ulcer0.29701502

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.05615836
2Intrahepatic cholestasis (HP:0001406)6.71601309
3Deep venous thrombosis (HP:0002625)6.69233812
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.19475574
5Prolonged partial thromboplastin time (HP:0003645)6.18006564
6Xanthomatosis (HP:0000991)5.87600768
7Hypobetalipoproteinemia (HP:0003563)5.72157030
8Hyperlipoproteinemia (HP:0010980)5.30876477
9Complement deficiency (HP:0004431)4.83709913
10Joint hemorrhage (HP:0005261)4.75135436
11Hyperammonemia (HP:0001987)4.57537989
12Ketosis (HP:0001946)4.44246995
13Hypolipoproteinemia (HP:0010981)4.42606208
14Hyperglycinemia (HP:0002154)4.35986841
15Hyperglycinuria (HP:0003108)4.30646750
16Hypoglycemic coma (HP:0001325)4.22334988
17Epidermoid cyst (HP:0200040)4.19302390
18Abnormality of glutamine family amino acid metabolism (HP:0010902)4.17427628
19Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.14693712
20Abnormality of serine family amino acid metabolism (HP:0010894)4.08728682
21Abnormality of glycine metabolism (HP:0010895)4.08728682
22Abnormality of the common coagulation pathway (HP:0010990)4.06179903
23Abnormality of sulfur amino acid metabolism (HP:0004339)4.03501154
24Abnormality of methionine metabolism (HP:0010901)4.02351697
25Abnormality of aspartate family amino acid metabolism (HP:0010899)4.00754177
26Hypoalphalipoproteinemia (HP:0003233)3.99986425
27Fat malabsorption (HP:0002630)3.93649826
28Abnormality of fatty-acid metabolism (HP:0004359)3.87065816
29Conjugated hyperbilirubinemia (HP:0002908)3.83219444
30Abnormality of the intrinsic pathway (HP:0010989)3.69843896
31Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.62913096
32Abnormality of pyrimidine metabolism (HP:0004353)3.55095707
33Abnormality of complement system (HP:0005339)3.50891373
34Hypercholesterolemia (HP:0003124)3.48161779
35Ketoacidosis (HP:0001993)3.37569319
36Eczematoid dermatitis (HP:0000976)3.26648333
37Hyperbilirubinemia (HP:0002904)3.26302226
38Abnormality of nucleobase metabolism (HP:0010932)3.11844749
39Nephritis (HP:0000123)3.09799294
40Delayed CNS myelination (HP:0002188)3.08758749
41Abnormality of dicarboxylic acid metabolism (HP:0010995)3.05582783
42Dicarboxylic aciduria (HP:0003215)3.05582783
43Metabolic acidosis (HP:0001942)3.00088599
44Abnormality of serum amino acid levels (HP:0003112)2.99784466
45Steatorrhea (HP:0002570)2.96988718
46Generalized aminoaciduria (HP:0002909)2.92413601
47Purpura (HP:0000979)2.91319815
48Abnormality of purine metabolism (HP:0004352)2.90219270
49Myocardial infarction (HP:0001658)2.88455170
50Vascular calcification (HP:0004934)2.88403991
51Lethargy (HP:0001254)2.77235081
52Gastrointestinal infarctions (HP:0005244)2.77178497
53Renal cortical cysts (HP:0000803)2.68294554
54Hepatocellular carcinoma (HP:0001402)2.67675217
55Cerebral edema (HP:0002181)2.64858598
56Spontaneous abortion (HP:0005268)2.61743864
57Megaloblastic anemia (HP:0001889)2.60259459
58Systemic lupus erythematosus (HP:0002725)2.58690589
59Hypoglycemic seizures (HP:0002173)2.56256212
60Gout (HP:0001997)2.55732164
61Increased serum ferritin (HP:0003281)2.53090846
62Cardiovascular calcification (HP:0011915)2.52443290
63Joint swelling (HP:0001386)2.47250143
64Skin nodule (HP:0200036)2.44743488
65Pancreatitis (HP:0001733)2.41062499
66Hypochromic microcytic anemia (HP:0004840)2.39743640
67Abnormality of macrophages (HP:0004311)2.36741269
68Recurrent abscess formation (HP:0002722)2.36059003
69Orchitis (HP:0100796)2.33266891
70Abnormality of iron homeostasis (HP:0011031)2.33227316
71Menorrhagia (HP:0000132)2.30126923
72Myositis (HP:0100614)2.28475488
73Gingival bleeding (HP:0000225)2.26673179
74Acanthocytosis (HP:0001927)2.26419948
75Glomerulonephritis (HP:0000099)2.26377636
76Hypochromic anemia (HP:0001931)2.26311113
77Vomiting (HP:0002013)2.26247264
78Amyloidosis (HP:0011034)2.25565762
79Recurrent gram-negative bacterial infections (HP:0005420)2.25040969
80Abnormal gallbladder morphology (HP:0012437)2.24884053
81Increased IgM level (HP:0003496)2.24443855
82Mitral stenosis (HP:0001718)2.24292711
83Anorexia (HP:0002039)2.24078306
84Enlarged kidneys (HP:0000105)2.21603543
85Proximal tubulopathy (HP:0000114)2.21167733
86Pulmonary embolism (HP:0002204)2.20277084
87Irritability (HP:0000737)2.15872219
88Esophageal varix (HP:0002040)2.15265168
89Cholelithiasis (HP:0001081)2.15249832
90Abnormality of transition element cation homeostasis (HP:0011030)2.11331108
91Neonatal onset (HP:0003623)2.11190907
92Late onset (HP:0003584)2.10050049
93Cheilitis (HP:0100825)2.09753456
94Hydroxyprolinuria (HP:0003080)2.09511003
95Abnormality of proline metabolism (HP:0010907)2.09511003
96Brushfield spots (HP:0001088)2.09279677
97Spastic diplegia (HP:0001264)2.07694755
98Sensorimotor neuropathy (HP:0007141)2.07219315
99Opisthotonus (HP:0002179)2.06940406
100Hyperinsulinemic hypoglycemia (HP:0000825)2.06919786
101Retrobulbar optic neuritis (HP:0100654)2.04146328
102Optic neuritis (HP:0100653)2.04146328
103Malnutrition (HP:0004395)2.02900310
104Abnormality of urine glucose concentration (HP:0011016)2.01569394
105Glycosuria (HP:0003076)2.01569394
106Alkalosis (HP:0001948)2.00296946
107Elevated hepatic transaminases (HP:0002910)1.97624119
108Chronic diarrhea (HP:0002028)1.96124445
109Thrombophlebitis (HP:0004418)1.96122528
110Encephalitis (HP:0002383)1.92262401
111Widely patent fontanelles and sutures (HP:0004492)1.91925517
112Elevated erythrocyte sedimentation rate (HP:0003565)1.88888444
113Hemorrhage of the eye (HP:0011885)1.88876452
114Nausea (HP:0002018)1.88598785
115Rickets (HP:0002748)1.88181653
116Increased purine levels (HP:0004368)1.86420207
117Hyperuricemia (HP:0002149)1.86420207
118Abnormality of glycolipid metabolism (HP:0010969)1.85393538
119Abnormality of liposaccharide metabolism (HP:0010968)1.85393538
120Abnormality of glycosphingolipid metabolism (HP:0004343)1.85393538
121Hyperglycemia (HP:0003074)1.85333139
122Epistaxis (HP:0000421)1.84525311
123Abnormality of the gallbladder (HP:0005264)1.84332850
124Poikilocytosis (HP:0004447)1.83607960
125Cerebral palsy (HP:0100021)1.82814768
126Abnormality of vitamin metabolism (HP:0100508)1.81250803
127Symptomatic seizures (HP:0011145)1.80530943
128Abnormal enzyme/coenzyme activity (HP:0012379)1.80377766
129Pigmentary retinal degeneration (HP:0001146)1.79910050
130Hypertriglyceridemia (HP:0002155)1.79260159
131Dysostosis multiplex (HP:0000943)1.77793015
132Gingivitis (HP:0000230)1.76492264
133Abnormality of alkaline phosphatase activity (HP:0004379)1.75740293
134Vacuolated lymphocytes (HP:0001922)1.73430266
135Hypophosphatemia (HP:0002148)1.72356558
136Meningitis (HP:0001287)1.72169291
137Hyperphosphaturia (HP:0003109)1.69207265
138Nasal polyposis (HP:0100582)1.68598420

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.84971055
2ERN14.03182218
3FGFR44.02841418
4SIK13.62562591
5INSRR3.52522984
6TAOK32.92320439
7RIPK42.42904246
8FRK2.08108537
9FLT31.95774059
10PRPF4B1.82672920
11IRAK31.82074433
12PKN21.81824517
13MST1R1.81474772
14TYK21.75414709
15TLK11.74173173
16ERBB41.71337133
17SMG11.66764130
18ACVR1B1.60906341
19MAPK111.59208429
20MAP3K141.54648511
21MAP3K71.48456545
22TESK21.47960161
23PIK3CG1.46831706
24TRIB31.41961111
25PRKG21.40078621
26TIE11.39901847
27MAP2K41.38951060
28EPHA21.35858967
29NEK91.34729323
30PTK61.33285323
31PRKAA21.27989923
32BLK1.22304671
33PINK11.20205669
34EPHB11.19836454
35MAPK151.16844236
36MAP3K31.16572622
37IKBKE1.16216821
38JAK11.16165756
39MAP2K31.15027974
40TNK21.12116462
41EPHA31.10772910
42JAK21.10479854
43TBK11.09529381
44STK391.09175108
45FGR1.08170621
46FGFR21.06652015
47LCK1.04958787
48TGFBR21.02346536
49PRKD20.99843063
50STK38L0.99713984
51TAOK10.97145610
52MYLK0.95459459
53CAMK1D0.95315127
54CDC42BPA0.95097214
55IRAK10.94196456
56LATS10.92662037
57NME20.91172644
58GRK60.89155823
59SGK20.85904377
60MAP2K60.85483163
61ICK0.85433199
62SYK0.85235164
63MATK0.84041769
64MAP2K20.83157911
65LYN0.82764771
66CSK0.82615582
67MAPK40.81284764
68HCK0.80729638
69ABL20.79216436
70SGK30.78273344
71KDR0.77998462
72GRK10.77592835
73IRAK40.75973903
74NLK0.74706095
75FGFR10.74059078
76MAP4K10.73838987
77DAPK20.73232173
78ERBB20.72752615
79PIM10.72549428
80PRKCQ0.69490731
81PIM20.69001840
82IRAK20.68894285
83ZAP700.66365378
84MAPK70.66232946
85JAK30.66076467
86FGFR30.64748413
87PRKCZ0.63782624
88PIK3CA0.63359172
89PRKAA10.62486076
90MAPK120.62386019
91RPS6KA20.61219814
92GRK70.59165465
93RPS6KC10.58287757
94RPS6KL10.58287757
95PRKACG0.57449616
96SGK4940.56138502
97SGK2230.56138502
98FES0.55831734
99CDK60.55779901
100LRRK20.54628818
101PAK40.54083386
102MAP3K130.53666147
103CSF1R0.53179841
104BTK0.52864206
105TAOK20.52613247
106RPS6KA60.51999000
107STK100.51686467
108RET0.51133617
109CAMK40.50302185
110GSK3A0.50273097
111DDR20.50092647
112WNK40.49131150
113MET0.48432962
114CAMK2G0.48361766
115PDPK10.48198103
116RIPK10.48068783
117KIT0.47101690
118NUAK10.45680575
119BMPR20.45338935
120LMTK20.45309645
121PDK20.45250356
122AKT30.44212559
123CHUK0.43717231
124TXK0.43586000
125ITK0.41787234
126HIPK20.40652209
127SRC0.38436927
128PTK2B0.38398116
129IKBKB0.37489968
130CDK40.37482089
131FYN0.37207906
132TEC0.37029784
133MAP2K10.37000380
134DYRK1B0.36528219
135IGF1R0.36440247
136MAP3K50.36335112
137PDK30.35769345
138PDK40.35769345
139CAMK1G0.34718941
140PDK10.33371862
141MAP3K110.33103965
142PKN10.30645930
143MAP3K10.29630479

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.20029875
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.33346794
3Nitrogen metabolism_Homo sapiens_hsa009103.08064753
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.08025629
5Arginine biosynthesis_Homo sapiens_hsa002202.83272332
6Tryptophan metabolism_Homo sapiens_hsa003802.69823725
7Fatty acid degradation_Homo sapiens_hsa000712.67614477
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.61614039
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.61512024
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.59485104
11Complement and coagulation cascades_Homo sapiens_hsa046102.54005295
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.42328447
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.34306100
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.24330013
15Propanoate metabolism_Homo sapiens_hsa006402.23215808
16Peroxisome_Homo sapiens_hsa041462.18764898
17Butanoate metabolism_Homo sapiens_hsa006502.18154443
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.99686981
19Chemical carcinogenesis_Homo sapiens_hsa052041.98841162
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.96374546
21PPAR signaling pathway_Homo sapiens_hsa033201.95587693
22Fatty acid metabolism_Homo sapiens_hsa012121.93870121
23Histidine metabolism_Homo sapiens_hsa003401.88566171
24beta-Alanine metabolism_Homo sapiens_hsa004101.80786758
25Caffeine metabolism_Homo sapiens_hsa002321.78262820
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.68505875
27Sulfur metabolism_Homo sapiens_hsa009201.68350273
28Retinol metabolism_Homo sapiens_hsa008301.67708436
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.67612772
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.67402762
31Staphylococcus aureus infection_Homo sapiens_hsa051501.66047947
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.60236213
33Selenocompound metabolism_Homo sapiens_hsa004501.55239859
34Phenylalanine metabolism_Homo sapiens_hsa003601.50663467
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50607123
36Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.50500382
37Fatty acid elongation_Homo sapiens_hsa000621.46027257
38Pyruvate metabolism_Homo sapiens_hsa006201.41461801
39Bile secretion_Homo sapiens_hsa049761.38457964
40Starch and sucrose metabolism_Homo sapiens_hsa005001.36999979
41Tyrosine metabolism_Homo sapiens_hsa003501.35588301
42ABC transporters_Homo sapiens_hsa020101.30643104
43Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.30609824
44Folate biosynthesis_Homo sapiens_hsa007901.25884476
45Fat digestion and absorption_Homo sapiens_hsa049751.20211626
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.19290047
47Carbon metabolism_Homo sapiens_hsa012001.14006839
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.13650295
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.09271480
50Steroid biosynthesis_Homo sapiens_hsa001001.06615986
51Biosynthesis of amino acids_Homo sapiens_hsa012301.04827297
52Sulfur relay system_Homo sapiens_hsa041221.04372071
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01318251
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.00388679
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.97546708
56Arginine and proline metabolism_Homo sapiens_hsa003300.93593249
57Vitamin digestion and absorption_Homo sapiens_hsa049770.93479282
58Mineral absorption_Homo sapiens_hsa049780.93095976
59Lysine degradation_Homo sapiens_hsa003100.85040264
60Graft-versus-host disease_Homo sapiens_hsa053320.82286850
61Glycerolipid metabolism_Homo sapiens_hsa005610.81163827
62Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76022765
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74342623
64Glutathione metabolism_Homo sapiens_hsa004800.73445351
65Vitamin B6 metabolism_Homo sapiens_hsa007500.68644295
66Allograft rejection_Homo sapiens_hsa053300.65245867
67Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.64956109
68Fatty acid biosynthesis_Homo sapiens_hsa000610.60837989
69One carbon pool by folate_Homo sapiens_hsa006700.57013174
70Autoimmune thyroid disease_Homo sapiens_hsa053200.56787714
71Pentose phosphate pathway_Homo sapiens_hsa000300.53344368
72Metabolic pathways_Homo sapiens_hsa011000.50768859
73Leishmaniasis_Homo sapiens_hsa051400.41472881
74Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40506068
75NF-kappa B signaling pathway_Homo sapiens_hsa040640.38002585
76Type I diabetes mellitus_Homo sapiens_hsa049400.36321686
77Galactose metabolism_Homo sapiens_hsa000520.35729652
78Primary immunodeficiency_Homo sapiens_hsa053400.35235891
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35031846
80Systemic lupus erythematosus_Homo sapiens_hsa053220.33129837
81Insulin resistance_Homo sapiens_hsa049310.31445237
82Linoleic acid metabolism_Homo sapiens_hsa005910.29750041
83Fructose and mannose metabolism_Homo sapiens_hsa000510.28996637
84Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.27709513
85Adipocytokine signaling pathway_Homo sapiens_hsa049200.26546291
86Protein digestion and absorption_Homo sapiens_hsa049740.25759856
87Antigen processing and presentation_Homo sapiens_hsa046120.25335713
88Prion diseases_Homo sapiens_hsa050200.23633505
89Asthma_Homo sapiens_hsa053100.18814583
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.18804493
91Osteoclast differentiation_Homo sapiens_hsa043800.17682610
92Toll-like receptor signaling pathway_Homo sapiens_hsa046200.17552421
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.14145601
94Glucagon signaling pathway_Homo sapiens_hsa049220.06271230
95Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.05678247
96AMPK signaling pathway_Homo sapiens_hsa041520.03019890
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.01254843
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.00077455
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.2188663
100Circadian rhythm_Homo sapiens_hsa04710-0.2172583
101Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2143224
102Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2056050
103Ether lipid metabolism_Homo sapiens_hsa00565-0.2044120
104Pertussis_Homo sapiens_hsa05133-0.1991723
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1945337
106Other glycan degradation_Homo sapiens_hsa00511-0.1943856
107African trypanosomiasis_Homo sapiens_hsa05143-0.1790734
108Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1573281
109Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.1525283
110RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.1439227
111Renin-angiotensin system_Homo sapiens_hsa04614-0.1340838
112Insulin signaling pathway_Homo sapiens_hsa04910-0.0858377
113Hepatitis C_Homo sapiens_hsa05160-0.0710154
114Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0666038
115Regulation of autophagy_Homo sapiens_hsa04140-0.0586823
116Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0017366

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