Rank | Gene Set | Z-score |
---|---|---|
1 | Golgi transport vesicle coating (GO:0048200) | 9.06191775 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 9.06191775 |
3 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 6.77711683 |
4 | protein retention in ER lumen (GO:0006621) | 6.10273689 |
5 | signal peptide processing (GO:0006465) | 5.89782559 |
6 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 5.71630806 |
7 | endocrine pancreas development (GO:0031018) | 5.56578499 |
8 | COPII vesicle coating (GO:0048208) | 5.47071122 |
9 | exocrine pancreas development (GO:0031017) | 5.03252540 |
10 | peptide hormone processing (GO:0016486) | 4.90963261 |
11 | nitric oxide biosynthetic process (GO:0006809) | 4.78631349 |
12 | ER overload response (GO:0006983) | 4.73813463 |
13 | melanin biosynthetic process (GO:0042438) | 4.73764228 |
14 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 4.71393398 |
15 | glandular epithelial cell differentiation (GO:0002067) | 4.65495427 |
16 | desmosome organization (GO:0002934) | 4.57696152 |
17 | sperm motility (GO:0030317) | 4.49673453 |
18 | positive regulation of nuclease activity (GO:0032075) | 4.42507698 |
19 | intra-Golgi vesicle-mediated transport (GO:0006891) | 4.42228949 |
20 | ketone body metabolic process (GO:1902224) | 4.40827228 |
21 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.38148665 |
22 | nucleotide-sugar biosynthetic process (GO:0009226) | 4.36806011 |
23 | intestinal epithelial cell development (GO:0060576) | 4.36012922 |
24 | fusion of sperm to egg plasma membrane (GO:0007342) | 4.32122820 |
25 | cell wall macromolecule metabolic process (GO:0044036) | 4.31894927 |
26 | cell wall macromolecule catabolic process (GO:0016998) | 4.31894927 |
27 | GDP-mannose metabolic process (GO:0019673) | 4.31328720 |
28 | protein maturation by protein folding (GO:0022417) | 4.31101661 |
29 | melanin metabolic process (GO:0006582) | 4.19410882 |
30 | sequestering of metal ion (GO:0051238) | 4.14931769 |
31 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 4.11541593 |
32 | cellular response to unfolded protein (GO:0034620) | 4.08671184 |
33 | acrosome assembly (GO:0001675) | 4.06438346 |
34 | protein N-linked glycosylation via asparagine (GO:0018279) | 4.05518705 |
35 | endoplasmic reticulum unfolded protein response (GO:0030968) | 4.04228120 |
36 | regulation of nuclease activity (GO:0032069) | 4.03326349 |
37 | peptidyl-asparagine modification (GO:0018196) | 4.02815570 |
38 | vesicle coating (GO:0006901) | 4.01039420 |
39 | acrosome reaction (GO:0007340) | 4.00046797 |
40 | negative regulation of glycogen biosynthetic process (GO:0045719) | 3.99670105 |
41 | keratinocyte development (GO:0003334) | 3.96822108 |
42 | regulation of water loss via skin (GO:0033561) | 3.90829757 |
43 | multicellular organism reproduction (GO:0032504) | 3.90426810 |
44 | cellular response to topologically incorrect protein (GO:0035967) | 3.88582097 |
45 | intestinal cholesterol absorption (GO:0030299) | 3.86387018 |
46 | secondary metabolite biosynthetic process (GO:0044550) | 3.85016021 |
47 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 3.81026498 |
48 | ER-nucleus signaling pathway (GO:0006984) | 3.78305317 |
49 | cellular ketone body metabolic process (GO:0046950) | 3.75274998 |
50 | axonemal dynein complex assembly (GO:0070286) | 3.72788748 |
51 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.67398606 |
52 | protein N-linked glycosylation (GO:0006487) | 3.67014928 |
53 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 3.65611617 |
54 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 3.65611617 |
55 | epithelial cilium movement (GO:0003351) | 3.63538047 |
56 | insulin secretion (GO:0030073) | 3.62889238 |
57 | response to endoplasmic reticulum stress (GO:0034976) | 3.62374138 |
58 | amyloid precursor protein catabolic process (GO:0042987) | 3.59487540 |
59 | spermatid development (GO:0007286) | 3.59197790 |
60 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.53151475 |
61 | nucleotide-sugar metabolic process (GO:0009225) | 3.52056784 |
62 | regulation of hexokinase activity (GO:1903299) | 3.50636630 |
63 | regulation of glucokinase activity (GO:0033131) | 3.50636630 |
64 | pharyngeal system development (GO:0060037) | 3.49803148 |
65 | reproduction (GO:0000003) | 3.47874171 |
66 | sperm-egg recognition (GO:0035036) | 3.47406929 |
67 | epithelial cell maturation (GO:0002070) | 3.47045349 |
68 | columnar/cuboidal epithelial cell development (GO:0002066) | 3.43917049 |
69 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.42610508 |
70 | response to unfolded protein (GO:0006986) | 3.38021265 |
71 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.37417186 |
72 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.37104835 |
73 | cilium movement (GO:0003341) | 3.36520601 |
74 | macroautophagy (GO:0016236) | 3.36189556 |
75 | left/right pattern formation (GO:0060972) | 3.34374742 |
76 | intraciliary transport (GO:0042073) | 3.32824370 |
77 | intestinal absorption (GO:0050892) | 3.32336015 |
78 | negative regulation of glycogen metabolic process (GO:0070874) | 3.31075117 |
79 | interleukin-1-mediated signaling pathway (GO:0070498) | 3.30461974 |
80 | short-chain fatty acid metabolic process (GO:0046459) | 3.30385590 |
81 | multicellular organismal water homeostasis (GO:0050891) | 3.30317192 |
82 | norepinephrine metabolic process (GO:0042415) | 3.28175571 |
83 | positive regulation of insulin secretion (GO:0032024) | 3.27838655 |
84 | type B pancreatic cell development (GO:0003323) | 3.25769537 |
85 | digestion (GO:0007586) | 3.23649255 |
86 | plasma membrane fusion (GO:0045026) | 3.22536767 |
87 | response to topologically incorrect protein (GO:0035966) | 3.22534477 |
88 | nucleoside diphosphate catabolic process (GO:0009134) | 3.22086040 |
89 | xenobiotic catabolic process (GO:0042178) | 3.21873361 |
90 | cellular zinc ion homeostasis (GO:0006882) | 3.17563278 |
91 | protein targeting to Golgi (GO:0000042) | 3.17499181 |
92 | ER to Golgi vesicle-mediated transport (GO:0006888) | 3.16146428 |
93 | cell-cell recognition (GO:0009988) | 3.15594019 |
94 | sphingomyelin metabolic process (GO:0006684) | 3.14511255 |
95 | protein localization to Golgi apparatus (GO:0034067) | 3.13893023 |
96 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.13782652 |
97 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.13026530 |
98 | establishment of skin barrier (GO:0061436) | 3.12368401 |
99 | detection of calcium ion (GO:0005513) | 3.11451458 |
100 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.09025481 |
101 | L-phenylalanine metabolic process (GO:0006558) | 3.09025481 |
102 | zinc ion transmembrane transport (GO:0071577) | 3.08881102 |
103 | regulation of acrosome reaction (GO:0060046) | 3.07318664 |
104 | sperm capacitation (GO:0048240) | 3.06814151 |
105 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.04974942 |
106 | regulation of insulin secretion (GO:0050796) | 3.01362563 |
107 | peptide catabolic process (GO:0043171) | 3.00318440 |
108 | toxin transport (GO:1901998) | 2.99227507 |
109 | cell redox homeostasis (GO:0045454) | 2.99187495 |
110 | water homeostasis (GO:0030104) | 2.98406561 |
111 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.98126900 |
112 | positive regulation of keratinocyte differentiation (GO:0045618) | 2.97930663 |
113 | biotin metabolic process (GO:0006768) | 2.96186887 |
114 | regulation of cilium movement (GO:0003352) | 2.95977328 |
115 | ceramide catabolic process (GO:0046514) | 2.95291155 |
116 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.94689405 |
117 | calcium ion-dependent exocytosis (GO:0017156) | 2.93731585 |
118 | auditory receptor cell differentiation (GO:0042491) | 2.93425236 |
119 | establishment of protein localization to Golgi (GO:0072600) | 2.93226949 |
120 | glutathione derivative biosynthetic process (GO:1901687) | 2.92187884 |
121 | glutathione derivative metabolic process (GO:1901685) | 2.92187884 |
122 | glandular epithelial cell development (GO:0002068) | 2.90489246 |
123 | amino-acid betaine transport (GO:0015838) | 2.88480376 |
124 | carnitine transport (GO:0015879) | 2.88480376 |
125 | oocyte development (GO:0048599) | 2.87302546 |
126 | cellular response to vitamin D (GO:0071305) | 2.87206010 |
127 | binding of sperm to zona pellucida (GO:0007339) | 2.87079445 |
128 | regulation of autophagic vacuole assembly (GO:2000785) | 2.86585327 |
129 | phenylpropanoid metabolic process (GO:0009698) | 2.85110288 |
130 | organic cation transport (GO:0015695) | 2.83233907 |
131 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.83024690 |
132 | regulation of cardioblast proliferation (GO:0003264) | 2.83024690 |
133 | regulation of cell proliferation involved in kidney development (GO:1901722) | 2.82495000 |
134 | lactate metabolic process (GO:0006089) | 2.81574731 |
135 | fucose metabolic process (GO:0006004) | 2.81430286 |
136 | positive regulation of glycolytic process (GO:0045821) | 2.80795705 |
137 | Golgi organization (GO:0007030) | 2.80667137 |
138 | glycolipid catabolic process (GO:0019377) | 2.80205904 |
139 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.79990845 |
140 | myelin maintenance (GO:0043217) | 2.75818412 |
141 | positive regulation of macroautophagy (GO:0016239) | 2.75224121 |
142 | zinc ion homeostasis (GO:0055069) | 2.72645645 |
143 | negative regulation of neurological system process (GO:0031645) | 2.72467705 |
144 | prostate gland growth (GO:0060736) | 2.71168972 |
145 | positive regulation of epidermal cell differentiation (GO:0045606) | 2.68685249 |
146 | diol metabolic process (GO:0034311) | 2.67332447 |
147 | flavonoid metabolic process (GO:0009812) | 2.66976642 |
148 | pigment cell differentiation (GO:0050931) | 2.66760486 |
149 | amyloid precursor protein metabolic process (GO:0042982) | 2.65646824 |
150 | ear development (GO:0043583) | 2.64789643 |
151 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 2.63758333 |
152 | inositol phosphate catabolic process (GO:0071545) | 2.63616284 |
153 | cardiac right ventricle morphogenesis (GO:0003215) | 2.61629706 |
154 | glutathione biosynthetic process (GO:0006750) | 2.61309455 |
155 | zinc ion transport (GO:0006829) | 2.56576130 |
156 | columnar/cuboidal epithelial cell differentiation (GO:0002065) | 2.55805117 |
157 | phenol-containing compound biosynthetic process (GO:0046189) | 2.53629582 |
158 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.51445269 |
159 | inositol phosphate dephosphorylation (GO:0046855) | 2.51445269 |
160 | vitamin transmembrane transport (GO:0035461) | 2.49341587 |
161 | branched-chain amino acid catabolic process (GO:0009083) | 2.48823225 |
162 | polyol catabolic process (GO:0046174) | 2.47340511 |
163 | regulation of vacuole organization (GO:0044088) | 2.46146091 |
164 | motile cilium assembly (GO:0044458) | 2.45585084 |
165 | phosphatidylethanolamine metabolic process (GO:0046337) | 2.43833610 |
166 | phosphate ion homeostasis (GO:0055062) | 2.43394056 |
167 | trivalent inorganic anion homeostasis (GO:0072506) | 2.43394056 |
168 | melanocyte differentiation (GO:0030318) | 2.42636513 |
169 | early endosome to late endosome transport (GO:0045022) | 2.42272327 |
170 | tight junction assembly (GO:0070830) | 2.41852303 |
171 | removal of superoxide radicals (GO:0019430) | 2.41479233 |
172 | cellular response to superoxide (GO:0071451) | 2.41479233 |
173 | cellular response to oxygen radical (GO:0071450) | 2.41479233 |
174 | negative regulation of organelle assembly (GO:1902116) | 2.39637653 |
175 | epithelial cell fate commitment (GO:0072148) | 2.36650978 |
176 | regulation of keratinocyte differentiation (GO:0045616) | 2.35644357 |
177 | axoneme assembly (GO:0035082) | 2.35349501 |
178 | primary alcohol catabolic process (GO:0034310) | 2.35209344 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 6.10830550 |
2 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 4.25896341 |
3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.59192739 |
4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.39042825 |
5 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.27772249 |
6 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.88974391 |
7 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 2.50607864 |
8 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.36736414 |
9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.19464596 |
10 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.18975908 |
11 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.05626955 |
12 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.02908515 |
13 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 2.02773699 |
14 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.94514125 |
15 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.89685186 |
16 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.81946218 |
17 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.78063155 |
18 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.77686798 |
19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.77144483 |
20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.74383494 |
21 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.72187533 |
22 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.71585684 |
23 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.69459209 |
24 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.68368561 |
25 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.67754565 |
26 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.63610574 |
27 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.62403522 |
28 | GATA1_22025678_ChIP-Seq_K562_Human | 1.60405541 |
29 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.58954482 |
30 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.57742452 |
31 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.57329266 |
32 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.57029769 |
33 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.54861976 |
34 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.53229092 |
35 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.53106414 |
36 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.51546577 |
37 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.48491562 |
38 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.47122370 |
39 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.46284475 |
40 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.46121796 |
41 | * HOXB7_26014856_ChIP-Seq_BT474_Human | 1.46023744 |
42 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.46020801 |
43 | * ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.45954770 |
44 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.45780381 |
45 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.45695960 |
46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.45087442 |
47 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44736174 |
48 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.44595209 |
49 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.44444502 |
50 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.43717595 |
51 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.42936641 |
52 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.40584755 |
53 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.39924215 |
54 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.38240391 |
55 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.37508174 |
56 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35979270 |
57 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.34527489 |
58 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.33793157 |
59 | VDR_22108803_ChIP-Seq_LS180_Human | 1.33581015 |
60 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.33042962 |
61 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.31184401 |
62 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.30749689 |
63 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.30381919 |
64 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.29511014 |
65 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.29047864 |
66 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.28501186 |
67 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.28025029 |
68 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.27687780 |
69 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.27500153 |
70 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.27053112 |
71 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.26227242 |
72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.25349645 |
73 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.25282110 |
74 | * CDX2_22108803_ChIP-Seq_LS180_Human | 1.25146826 |
75 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.24213324 |
76 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.23145874 |
77 | ERA_21632823_ChIP-Seq_H3396_Human | 1.22629086 |
78 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.20660771 |
79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.20497000 |
80 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.20027966 |
81 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.18727101 |
82 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.18155326 |
83 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.17773082 |
84 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.16046349 |
85 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.15057476 |
86 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.14563783 |
87 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.14441393 |
88 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.13859319 |
89 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.12841205 |
90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12151501 |
91 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11905672 |
92 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10650355 |
93 | * ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.08658106 |
94 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.08594974 |
95 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.07888813 |
96 | * KDM2B_26808549_Chip-Seq_REH_Human | 1.07625650 |
97 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07223122 |
98 | * AHR_22903824_ChIP-Seq_MCF-7_Human | 1.06799210 |
99 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.06287905 |
100 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.05866361 |
101 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.05676725 |
102 | STAT3_23295773_ChIP-Seq_U87_Human | 1.05634133 |
103 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.05590445 |
104 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.04572544 |
105 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.03951262 |
106 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.03731605 |
107 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.03723574 |
108 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.02640003 |
109 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.01831868 |
110 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.01740098 |
111 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.01641634 |
112 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.01641634 |
113 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.00365014 |
114 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.99941698 |
115 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.99525253 |
116 | * FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99147671 |
117 | * FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99147671 |
118 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98643756 |
119 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.97739417 |
120 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.97300172 |
121 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.97106722 |
122 | AR_25329375_ChIP-Seq_VCAP_Human | 0.96565714 |
123 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.96471089 |
124 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.96429831 |
125 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.96257838 |
126 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94343994 |
127 | * CJUN_26792858_Chip-Seq_BT549_Human | 0.94026159 |
128 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.93520773 |
129 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.93457759 |
130 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.93342098 |
131 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.92390310 |
132 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.92115510 |
133 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.91712932 |
134 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.91241586 |
135 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.90879996 |
136 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.89681336 |
137 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.89579157 |
138 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89440651 |
139 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.89029733 |
140 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.88734203 |
141 | * GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.87855315 |
142 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87768098 |
143 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.87378806 |
144 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.86668322 |
145 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.86549032 |
146 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.86347177 |
147 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.84586424 |
148 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.84109511 |
149 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.82215319 |
150 | * GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.81636286 |
151 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.81424843 |
152 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.80188666 |
153 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.79936264 |
154 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.77311678 |
155 | ATF3_27146783_Chip-Seq_COLON_Human | 0.77256382 |
156 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.76794140 |
157 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.76128605 |
158 | * GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.75289051 |
159 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.73987577 |
160 | * RBPJ_21746931_ChIP-Seq_IB4_Human | 0.72944051 |
161 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.72145372 |
162 | * GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.71470104 |
163 | * HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.69991146 |
164 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.69399651 |
165 | * CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.68640027 |
166 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.67973555 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002877_abnormal_melanocyte_morpholog | 4.58262655 |
2 | MP0010386_abnormal_urinary_bladder | 4.19089388 |
3 | MP0002693_abnormal_pancreas_physiology | 3.71037496 |
4 | MP0003183_abnormal_peptide_metabolism | 3.70726437 |
5 | MP0005410_abnormal_fertilization | 3.65259654 |
6 | MP0004264_abnormal_extraembryonic_tissu | 3.35236564 |
7 | MP0005220_abnormal_exocrine_pancreas | 3.29333544 |
8 | MP0000678_abnormal_parathyroid_gland | 3.20004654 |
9 | MP0001944_abnormal_pancreas_morphology | 3.13295387 |
10 | MP0004043_abnormal_pH_regulation | 3.06733409 |
11 | MP0005379_endocrine/exocrine_gland_phen | 3.02965775 |
12 | MP0009780_abnormal_chondrocyte_physiolo | 3.00657187 |
13 | MP0000013_abnormal_adipose_tissue | 2.99502381 |
14 | MP0005075_abnormal_melanosome_morpholog | 2.91841210 |
15 | MP0002909_abnormal_adrenal_gland | 2.88239475 |
16 | MP0003195_calcinosis | 2.52191083 |
17 | MP0002138_abnormal_hepatobiliary_system | 2.48583560 |
18 | MP0001666_abnormal_nutrient_absorption | 2.47602654 |
19 | MP0010234_abnormal_vibrissa_follicle | 2.42867386 |
20 | MP0004381_abnormal_hair_follicle | 2.29233169 |
21 | MP0003283_abnormal_digestive_organ | 2.26608556 |
22 | MP0003806_abnormal_nucleotide_metabolis | 2.16955077 |
23 | MP0002876_abnormal_thyroid_physiology | 2.16627169 |
24 | MP0000427_abnormal_hair_cycle | 2.12800047 |
25 | MP0001765_abnormal_ion_homeostasis | 2.12475626 |
26 | MP0002796_impaired_skin_barrier | 2.07221743 |
27 | MP0002837_dystrophic_cardiac_calcinosis | 2.07070825 |
28 | MP0005310_abnormal_salivary_gland | 2.07042530 |
29 | MP0005083_abnormal_biliary_tract | 2.06310668 |
30 | MP0003868_abnormal_feces_composition | 2.05908587 |
31 | MP0005248_abnormal_Harderian_gland | 2.03591083 |
32 | MP0000383_abnormal_hair_follicle | 2.03251668 |
33 | MP0000371_diluted_coat_color | 1.97949819 |
34 | MP0000015_abnormal_ear_pigmentation | 1.96899484 |
35 | MP0005365_abnormal_bile_salt | 1.93410555 |
36 | MP0005645_abnormal_hypothalamus_physiol | 1.77459217 |
37 | MP0005171_absent_coat_pigmentation | 1.77007571 |
38 | MP0000003_abnormal_adipose_tissue | 1.76183673 |
39 | MP0002078_abnormal_glucose_homeostasis | 1.75317799 |
40 | MP0002254_reproductive_system_inflammat | 1.73257345 |
41 | MP0000613_abnormal_salivary_gland | 1.72830628 |
42 | MP0002163_abnormal_gland_morphology | 1.71102653 |
43 | MP0003300_gastrointestinal_ulcer | 1.69416332 |
44 | MP0001986_abnormal_taste_sensitivity | 1.69117387 |
45 | MP0002928_abnormal_bile_duct | 1.66748140 |
46 | MP0003878_abnormal_ear_physiology | 1.60924654 |
47 | MP0005377_hearing/vestibular/ear_phenot | 1.60924654 |
48 | MP0006072_abnormal_retinal_apoptosis | 1.58219638 |
49 | MP0001664_abnormal_digestion | 1.56543776 |
50 | MP0003136_yellow_coat_color | 1.49920125 |
51 | MP0002896_abnormal_bone_mineralization | 1.48753410 |
52 | MP0008875_abnormal_xenobiotic_pharmacok | 1.48131810 |
53 | MP0008004_abnormal_stomach_pH | 1.47990052 |
54 | MP0005084_abnormal_gallbladder_morpholo | 1.47681871 |
55 | MP0002009_preneoplasia | 1.47076954 |
56 | MP0002277_abnormal_respiratory_mucosa | 1.44878001 |
57 | MP0003123_paternal_imprinting | 1.43020720 |
58 | MP0000538_abnormal_urinary_bladder | 1.41140134 |
59 | MP0002234_abnormal_pharynx_morphology | 1.39804296 |
60 | MP0004019_abnormal_vitamin_homeostasis | 1.39151662 |
61 | MP0005174_abnormal_tail_pigmentation | 1.36336390 |
62 | MP0003866_abnormal_defecation | 1.31964699 |
63 | MP0001346_abnormal_lacrimal_gland | 1.30936221 |
64 | MP0000462_abnormal_digestive_system | 1.30574448 |
65 | MP0005646_abnormal_pituitary_gland | 1.29683138 |
66 | MP0005636_abnormal_mineral_homeostasis | 1.29347021 |
67 | MP0003698_abnormal_male_reproductive | 1.28761534 |
68 | MP0002098_abnormal_vibrissa_morphology | 1.25388767 |
69 | MP0004782_abnormal_surfactant_physiolog | 1.24989707 |
70 | MP0000377_abnormal_hair_follicle | 1.23857511 |
71 | MP0009643_abnormal_urine_homeostasis | 1.23357502 |
72 | MP0003953_abnormal_hormone_level | 1.22808403 |
73 | MP0001881_abnormal_mammary_gland | 1.21226943 |
74 | MP0001929_abnormal_gametogenesis | 1.20226764 |
75 | MP0005332_abnormal_amino_acid | 1.17665197 |
76 | MP0001756_abnormal_urination | 1.17173494 |
77 | MP0005670_abnormal_white_adipose | 1.17030443 |
78 | MP0000627_abnormal_mammary_gland | 1.16068858 |
79 | MP0002938_white_spotting | 1.14942275 |
80 | MP0002090_abnormal_vision | 1.12743132 |
81 | MP0010329_abnormal_lipoprotein_level | 1.11339339 |
82 | MP0004233_abnormal_muscle_weight | 1.08045270 |
83 | MP0003959_abnormal_lean_body | 1.06438067 |
84 | MP0001270_distended_abdomen | 1.05181717 |
85 | MP0000681_abnormal_thyroid_gland | 1.04232434 |
86 | MP0003045_fibrosis | 1.03893211 |
87 | MP0001873_stomach_inflammation | 1.03336089 |
88 | MP0008961_abnormal_basal_metabolism | 1.03270875 |
89 | MP0001324_abnormal_eye_pigmentation | 1.02940072 |
90 | MP0001502_abnormal_circadian_rhythm | 1.02813954 |
91 | MP0000470_abnormal_stomach_morphology | 1.00661790 |
92 | MP0002075_abnormal_coat/hair_pigmentati | 0.99874394 |
93 | MP0001186_pigmentation_phenotype | 0.97669858 |
94 | MP0002160_abnormal_reproductive_system | 0.96755196 |
95 | MP0005501_abnormal_skin_physiology | 0.96676340 |
96 | MP0002095_abnormal_skin_pigmentation | 0.95852844 |
97 | MP0010352_gastrointestinal_tract_polyps | 0.95651253 |
98 | MP0008877_abnormal_DNA_methylation | 0.95344112 |
99 | MP0005408_hypopigmentation | 0.94542236 |
100 | MP0009840_abnormal_foam_cell | 0.92469008 |
101 | MP0002638_abnormal_pupillary_reflex | 0.91845264 |
102 | MP0003252_abnormal_bile_duct | 0.89986999 |
103 | MP0004147_increased_porphyrin_level | 0.88823955 |
104 | MP0003936_abnormal_reproductive_system | 0.84981590 |
105 | MP0005058_abnormal_lysosome_morphology | 0.84555114 |
106 | MP0001299_abnormal_eye_distance/ | 0.83633047 |
107 | MP0005448_abnormal_energy_balance | 0.83132238 |
108 | MP0003718_maternal_effect | 0.83088501 |
109 | MP0005389_reproductive_system_phenotype | 0.82219878 |
110 | MP0008872_abnormal_physiological_respon | 0.80217440 |
111 | MP0005085_abnormal_gallbladder_physiolo | 0.79473631 |
112 | MP0001727_abnormal_embryo_implantation | 0.79157433 |
113 | MP0005257_abnormal_intraocular_pressure | 0.78707536 |
114 | MP0000367_abnormal_coat/_hair | 0.77539373 |
115 | MP0002060_abnormal_skin_morphology | 0.77018315 |
116 | MP0003941_abnormal_skin_development | 0.76126560 |
117 | MP0003122_maternal_imprinting | 0.74688347 |
118 | MP0001764_abnormal_homeostasis | 0.73889125 |
119 | MP0002822_catalepsy | 0.73444553 |
120 | MP0003943_abnormal_hepatobiliary_system | 0.72892940 |
121 | MP0000647_abnormal_sebaceous_gland | 0.72026782 |
122 | MP0002139_abnormal_hepatobiliary_system | 0.71082838 |
123 | MP0000579_abnormal_nail_morphology | 0.71072499 |
124 | MP0005375_adipose_tissue_phenotype | 0.71063379 |
125 | MP0003787_abnormal_imprinting | 0.69857277 |
126 | MP0003172_abnormal_lysosome_physiology | 0.69353836 |
127 | MP0003890_abnormal_embryonic-extraembry | 0.65484449 |
128 | MP0006054_spinal_hemorrhage | 0.65338697 |
129 | MP0010678_abnormal_skin_adnexa | 0.60729027 |
130 | MP0003795_abnormal_bone_structure | 0.60632726 |
131 | MP0001919_abnormal_reproductive_system | 0.59628937 |
132 | MP0002118_abnormal_lipid_homeostasis | 0.59517373 |
133 | MP0000631_abnormal_neuroendocrine_gland | 0.59152671 |
134 | MP0005253_abnormal_eye_physiology | 0.55535916 |
135 | MP0005535_abnormal_body_temperature | 0.55117998 |
136 | MP0005367_renal/urinary_system_phenotyp | 0.54919246 |
137 | MP0000516_abnormal_urinary_system | 0.54919246 |
138 | MP0005381_digestive/alimentary_phenotyp | 0.54440437 |
139 | MP0000372_irregular_coat_pigmentation | 0.53952460 |
140 | MP0003879_abnormal_hair_cell | 0.52069775 |
141 | MP0005187_abnormal_penis_morphology | 0.51892412 |
142 | MP0005334_abnormal_fat_pad | 0.51325132 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperinsulinemic hypoglycemia (HP:0000825) | 5.31246106 |
2 | Symptomatic seizures (HP:0011145) | 5.29163928 |
3 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 5.21716986 |
4 | Hypoglycemic seizures (HP:0002173) | 4.93855322 |
5 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.42857493 |
6 | Chronic bronchitis (HP:0004469) | 4.42232675 |
7 | Insulin-resistant diabetes mellitus (HP:0000831) | 4.29026279 |
8 | Hyperglycemia (HP:0003074) | 4.13419994 |
9 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.07073863 |
10 | Absent/shortened dynein arms (HP:0200106) | 4.07073863 |
11 | Abnormality of the intrinsic pathway (HP:0010989) | 3.88912967 |
12 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 3.76265594 |
13 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.61312695 |
14 | Hypoglycemic coma (HP:0001325) | 3.61108425 |
15 | Decreased circulating renin level (HP:0003351) | 3.47640874 |
16 | Abnormal pancreas size (HP:0012094) | 3.46506909 |
17 | Septate vagina (HP:0001153) | 3.40402866 |
18 | Large for gestational age (HP:0001520) | 3.26682696 |
19 | Hypokinesia (HP:0002375) | 3.26297459 |
20 | Hypoplasia of the fovea (HP:0007750) | 3.24543155 |
21 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.24543155 |
22 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.14232763 |
23 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.14232763 |
24 | Abnormal ciliary motility (HP:0012262) | 3.07688508 |
25 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.04499038 |
26 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.04499038 |
27 | Abnormal protein glycosylation (HP:0012346) | 3.04499038 |
28 | Abnormal glycosylation (HP:0012345) | 3.04499038 |
29 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.01976666 |
30 | Hypothermia (HP:0002045) | 2.99489467 |
31 | Hyperphosphatemia (HP:0002905) | 2.94183266 |
32 | Concave nail (HP:0001598) | 2.92820945 |
33 | Conjugated hyperbilirubinemia (HP:0002908) | 2.92731062 |
34 | Amelogenesis imperfecta (HP:0000705) | 2.88371194 |
35 | Rhinitis (HP:0012384) | 2.81826421 |
36 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.78430796 |
37 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.78430796 |
38 | Enlarged penis (HP:0000040) | 2.78308238 |
39 | Tubulointerstitial nephritis (HP:0001970) | 2.76483381 |
40 | Abnormality of the fovea (HP:0000493) | 2.76174493 |
41 | Ketosis (HP:0001946) | 2.76117036 |
42 | Retinal atrophy (HP:0001105) | 2.73093635 |
43 | Hyperactive renin-angiotensin system (HP:0000841) | 2.68147909 |
44 | Hypoplasia of dental enamel (HP:0006297) | 2.65230884 |
45 | Ocular albinism (HP:0001107) | 2.64303432 |
46 | Infertility (HP:0000789) | 2.63759137 |
47 | Breast carcinoma (HP:0003002) | 2.62978852 |
48 | Hyperkalemia (HP:0002153) | 2.61419369 |
49 | Lip pit (HP:0100267) | 2.60136488 |
50 | Congenital malformation of the right heart (HP:0011723) | 2.59592572 |
51 | Double outlet right ventricle (HP:0001719) | 2.59592572 |
52 | Hypokalemia (HP:0002900) | 2.58973052 |
53 | Tongue fasciculations (HP:0001308) | 2.57328158 |
54 | Type I transferrin isoform profile (HP:0003642) | 2.57080422 |
55 | Hyperparathyroidism (HP:0000843) | 2.56132947 |
56 | Testicular neoplasm (HP:0010788) | 2.54458510 |
57 | Late onset (HP:0003584) | 2.53942214 |
58 | J-shaped sella turcica (HP:0002680) | 2.53470710 |
59 | Abnormality of chloride homeostasis (HP:0011422) | 2.52295005 |
60 | Ketoacidosis (HP:0001993) | 2.50297413 |
61 | Cortical visual impairment (HP:0100704) | 2.47526216 |
62 | Vascular calcification (HP:0004934) | 2.46904032 |
63 | Abdominal distention (HP:0003270) | 2.46529220 |
64 | Unilateral renal agenesis (HP:0000122) | 2.43300211 |
65 | Flat capital femoral epiphysis (HP:0003370) | 2.43067440 |
66 | Exocrine pancreatic insufficiency (HP:0001738) | 2.42018306 |
67 | Diminished movement (HP:0002374) | 2.39015802 |
68 | Abnormality of potassium homeostasis (HP:0011042) | 2.37006576 |
69 | Dysostosis multiplex (HP:0000943) | 2.36653127 |
70 | Cystic liver disease (HP:0006706) | 2.36523230 |
71 | Patchy hypopigmentation of hair (HP:0011365) | 2.34685499 |
72 | Vacuolated lymphocytes (HP:0001922) | 2.32776667 |
73 | Male infertility (HP:0003251) | 2.28996478 |
74 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.28443970 |
75 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.27873670 |
76 | Abnormality of renin-angiotensin system (HP:0000847) | 2.27666988 |
77 | White forelock (HP:0002211) | 2.27635219 |
78 | Insulin resistance (HP:0000855) | 2.26884405 |
79 | Gout (HP:0001997) | 2.26634780 |
80 | Germ cell neoplasia (HP:0100728) | 2.25162916 |
81 | Generalized aminoaciduria (HP:0002909) | 2.25070345 |
82 | Iris hypopigmentation (HP:0007730) | 2.24906164 |
83 | Chronic hepatic failure (HP:0100626) | 2.24833993 |
84 | Generalized hypopigmentation (HP:0007513) | 2.24324383 |
85 | Right ventricular cardiomyopathy (HP:0011663) | 2.23363390 |
86 | Abnormality of cochlea (HP:0000375) | 2.20889182 |
87 | Bronchiectasis (HP:0002110) | 2.20738467 |
88 | Osteomalacia (HP:0002749) | 2.19973314 |
89 | Mucopolysacchariduria (HP:0008155) | 2.18989643 |
90 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.18989643 |
91 | Macroorchidism (HP:0000053) | 2.12560468 |
92 | Protuberant abdomen (HP:0001538) | 2.11485085 |
93 | Albinism (HP:0001022) | 2.11191851 |
94 | Abnormality of the renal cortex (HP:0011035) | 2.10393581 |
95 | Absent eyebrow (HP:0002223) | 2.10290909 |
96 | Hamartoma of the eye (HP:0010568) | 2.09674812 |
97 | Agitation (HP:0000713) | 2.09026978 |
98 | Abnormality of the renal medulla (HP:0100957) | 2.08701329 |
99 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.06421631 |
100 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.06421631 |
101 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.06421631 |
102 | Congenital sensorineural hearing impairment (HP:0008527) | 2.06171174 |
103 | Curly hair (HP:0002212) | 2.04233054 |
104 | Testicular atrophy (HP:0000029) | 2.01645992 |
105 | Blue irides (HP:0000635) | 1.98768923 |
106 | Medial flaring of the eyebrow (HP:0010747) | 1.98584788 |
107 | Nephronophthisis (HP:0000090) | 1.97397545 |
108 | Conjunctival hamartoma (HP:0100780) | 1.96955027 |
109 | Abnormality of nail color (HP:0100643) | 1.96303429 |
110 | Muscle fibrillation (HP:0010546) | 1.95929620 |
111 | Onycholysis (HP:0001806) | 1.94801196 |
112 | Abnormality of midbrain morphology (HP:0002418) | 1.94215056 |
113 | Molar tooth sign on MRI (HP:0002419) | 1.94215056 |
114 | Occipital encephalocele (HP:0002085) | 1.94046947 |
115 | Papillary thyroid carcinoma (HP:0002895) | 1.93992881 |
116 | Disproportionate short-trunk short stature (HP:0003521) | 1.93488652 |
117 | Hypomagnesemia (HP:0002917) | 1.93308093 |
118 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.91984341 |
119 | Villous atrophy (HP:0011473) | 1.91984341 |
120 | Sparse lateral eyebrow (HP:0005338) | 1.90097205 |
121 | Proximal tubulopathy (HP:0000114) | 1.89288621 |
122 | Glycosuria (HP:0003076) | 1.89229211 |
123 | Abnormality of urine glucose concentration (HP:0011016) | 1.89229211 |
124 | Bronchitis (HP:0012387) | 1.89210355 |
125 | Tubular atrophy (HP:0000092) | 1.89131828 |
126 | Progressive sensorineural hearing impairment (HP:0000408) | 1.88977535 |
127 | Cardiovascular calcification (HP:0011915) | 1.88802814 |
128 | Cutaneous melanoma (HP:0012056) | 1.87248706 |
129 | Glucose intolerance (HP:0000833) | 1.85951893 |
130 | Hypopigmentation of the fundus (HP:0007894) | 1.85674098 |
131 | Hypotension (HP:0002615) | 1.85255792 |
132 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.84272970 |
133 | Dysautonomia (HP:0002459) | 1.84170622 |
134 | Hyperthyroidism (HP:0000836) | 1.83553119 |
135 | Goiter (HP:0000853) | 1.83205006 |
136 | Nephropathy (HP:0000112) | 1.82508583 |
137 | Abnormality of magnesium homeostasis (HP:0004921) | 1.81969651 |
138 | Fat malabsorption (HP:0002630) | 1.81851339 |
139 | Tubulointerstitial abnormality (HP:0001969) | 1.81293420 |
140 | Abnormality of vitamin metabolism (HP:0100508) | 1.80434183 |
141 | Pancreatic fibrosis (HP:0100732) | 1.80116137 |
142 | Hyponatremia (HP:0002902) | 1.79856205 |
143 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.79767763 |
144 | Flattened epiphyses (HP:0003071) | 1.79311438 |
145 | Abnormality of the pons (HP:0007361) | 1.79260269 |
146 | Abnormality of vitamin B metabolism (HP:0004340) | 1.77981500 |
147 | Cone-rod dystrophy (HP:0000548) | 1.76100646 |
148 | Renal salt wasting (HP:0000127) | 1.75624214 |
149 | Microretrognathia (HP:0000308) | 1.74337203 |
150 | Congenital glaucoma (HP:0001087) | 1.72951157 |
151 | Steatorrhea (HP:0002570) | 1.72481811 |
Rank | Gene Set | Z-score |
---|---|---|
1 | INSRR | 6.81886756 |
2 | FRK | 3.74205125 |
3 | PRKD3 | 3.16386679 |
4 | MAPK15 | 3.15265239 |
5 | IRAK3 | 3.10604196 |
6 | STK38L | 2.87212372 |
7 | PASK | 2.82102809 |
8 | TAOK3 | 2.74319803 |
9 | AKT3 | 2.70443136 |
10 | MUSK | 2.43507796 |
11 | PKN2 | 2.41931705 |
12 | TESK1 | 2.34217745 |
13 | WNK4 | 2.23833014 |
14 | PDK4 | 2.20043119 |
15 | PDK3 | 2.20043119 |
16 | MAP3K2 | 2.19941420 |
17 | IRAK1 | 2.12141783 |
18 | RPS6KB2 | 1.97324890 |
19 | PDK2 | 1.84620301 |
20 | ERN1 | 1.80967276 |
21 | ACVR1B | 1.80600673 |
22 | FGFR2 | 1.75150384 |
23 | PTK6 | 1.70629997 |
24 | FLT3 | 1.69794833 |
25 | HIPK2 | 1.68583649 |
26 | MAP3K12 | 1.59185141 |
27 | STK24 | 1.56992505 |
28 | EPHA2 | 1.54494805 |
29 | EIF2AK1 | 1.51908052 |
30 | WEE1 | 1.50457174 |
31 | MAP2K2 | 1.46896008 |
32 | FER | 1.42354899 |
33 | EIF2AK3 | 1.26136051 |
34 | EPHA3 | 1.23833191 |
35 | IRAK4 | 1.18373839 |
36 | GRK1 | 1.16262794 |
37 | SIK1 | 1.15578179 |
38 | MAP3K4 | 1.11252805 |
39 | IRAK2 | 1.07107659 |
40 | ZAK | 1.02863859 |
41 | GRK6 | 1.02314838 |
42 | MST1R | 0.98019755 |
43 | TRIM28 | 0.97761116 |
44 | CDC42BPA | 0.96998471 |
45 | MST4 | 0.96485312 |
46 | MAP3K3 | 0.95148995 |
47 | PIK3CG | 0.93430904 |
48 | NUAK1 | 0.90676373 |
49 | MAP3K1 | 0.90235809 |
50 | PAK3 | 0.89101146 |
51 | MAP3K14 | 0.88821732 |
52 | WNK1 | 0.88544670 |
53 | FGFR3 | 0.86884691 |
54 | WNK3 | 0.86447670 |
55 | CDK12 | 0.86271557 |
56 | PHKG2 | 0.83648003 |
57 | PHKG1 | 0.83648003 |
58 | MET | 0.80661374 |
59 | RPS6KA2 | 0.80286034 |
60 | SGK2 | 0.79125807 |
61 | FGFR4 | 0.79092579 |
62 | PINK1 | 0.78645176 |
63 | DYRK1B | 0.78538188 |
64 | NTRK1 | 0.78429464 |
65 | LMTK2 | 0.78201950 |
66 | CDK7 | 0.77628896 |
67 | BCKDK | 0.76916779 |
68 | EEF2K | 0.75551704 |
69 | BMPR1B | 0.75547186 |
70 | PNCK | 0.73328842 |
71 | LATS1 | 0.73087788 |
72 | OXSR1 | 0.72670827 |
73 | SCYL2 | 0.72542332 |
74 | PTK2 | 0.72325967 |
75 | NME2 | 0.72060533 |
76 | CAMKK2 | 0.71332388 |
77 | MYLK | 0.69422106 |
78 | CHUK | 0.68374775 |
79 | STK3 | 0.68315897 |
80 | MAP2K7 | 0.67981902 |
81 | TRIB3 | 0.66160186 |
82 | ADRBK2 | 0.65607872 |
83 | NEK6 | 0.64513374 |
84 | PRKCE | 0.64458962 |
85 | RIPK1 | 0.63136534 |
86 | PRKAA1 | 0.62990038 |
87 | MAPKAPK3 | 0.60432905 |
88 | SIK3 | 0.59037159 |
89 | BMPR2 | 0.57985622 |
90 | PIK3CA | 0.57531801 |
91 | NLK | 0.56885617 |
92 | TAOK1 | 0.56627689 |
93 | RPS6KB1 | 0.56615182 |
94 | BRAF | 0.55813143 |
95 | PRKCI | 0.55330499 |
96 | SGK223 | 0.53941704 |
97 | SGK494 | 0.53941704 |
98 | MAP4K2 | 0.53196851 |
99 | ILK | 0.52371412 |
100 | NME1 | 0.50656654 |
101 | MATK | 0.49436626 |
102 | CSNK1G1 | 0.49257434 |
103 | JAK3 | 0.47390407 |
104 | PTK2B | 0.46895643 |
105 | STK38 | 0.46478515 |
106 | JAK1 | 0.46373743 |
107 | AKT2 | 0.46316933 |
108 | PAK4 | 0.46270312 |
109 | STK16 | 0.45943002 |
110 | DYRK3 | 0.45853753 |
111 | MAP2K1 | 0.44943394 |
112 | RET | 0.42786188 |
113 | PRKG2 | 0.42773321 |
114 | CAMK2D | 0.41989686 |
115 | CSNK1G3 | 0.41157475 |
116 | TNK2 | 0.40882460 |
117 | JAK2 | 0.40687127 |
118 | ERBB2 | 0.39626524 |
119 | BRSK2 | 0.38523923 |
120 | BRSK1 | 0.37464968 |
121 | SGK3 | 0.35967952 |
122 | ZAP70 | 0.35306063 |
123 | NTRK3 | 0.35142270 |
124 | PRKAA2 | 0.34764132 |
125 | PDGFRA | 0.34024801 |
126 | TRPM7 | 0.34023932 |
127 | MTOR | 0.33832766 |
128 | CSNK1A1 | 0.33526418 |
129 | CASK | 0.33513596 |
130 | ERBB3 | 0.32958944 |
131 | EPHB1 | 0.32785504 |
132 | MARK3 | 0.32098782 |
133 | MAP3K9 | 0.32090910 |
134 | CAMKK1 | 0.30400876 |
135 | STK39 | 0.29637990 |
136 | PDK1 | 0.29348858 |
137 | PRKCH | 0.29131648 |
138 | PDPK1 | 0.27392095 |
139 | GSK3A | 0.26077960 |
140 | CAMK1D | 0.24816092 |
141 | MAP2K6 | 0.24534153 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 7.40186894 |
2 | Protein export_Homo sapiens_hsa03060 | 5.49021457 |
3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.85838289 |
4 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 3.66564355 |
5 | Insulin secretion_Homo sapiens_hsa04911 | 2.63614664 |
6 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.44502954 |
7 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 2.28669689 |
8 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.13528508 |
9 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.12037252 |
10 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.11607075 |
11 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.07276318 |
12 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.02637523 |
13 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.93637965 |
14 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.92334538 |
15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.84870726 |
16 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.76160979 |
17 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.76052976 |
18 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.75766142 |
19 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.74927514 |
20 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.71665588 |
21 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.63973580 |
22 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.63191256 |
23 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.58659054 |
24 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.57187559 |
25 | Other glycan degradation_Homo sapiens_hsa00511 | 1.55427869 |
26 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.49998123 |
27 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.48385849 |
28 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.45581497 |
29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.38863660 |
30 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.38763958 |
31 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.37494476 |
32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.37254581 |
33 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.34131228 |
34 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.32882221 |
35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.31801015 |
36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.30301159 |
37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.29671294 |
38 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.27424749 |
39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.27285382 |
40 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.26799516 |
41 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.22953479 |
42 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.20285200 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.19338270 |
44 | Lysosome_Homo sapiens_hsa04142 | 1.16786016 |
45 | Peroxisome_Homo sapiens_hsa04146 | 1.15368485 |
46 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.11215094 |
47 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.07949465 |
48 | Tight junction_Homo sapiens_hsa04530 | 1.06579722 |
49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.05790270 |
50 | Mineral absorption_Homo sapiens_hsa04978 | 1.05677145 |
51 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.04835556 |
52 | Cocaine addiction_Homo sapiens_hsa05030 | 1.04503673 |
53 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.00314850 |
54 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.99378919 |
55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.95671895 |
56 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.95647997 |
57 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.95143779 |
58 | Taste transduction_Homo sapiens_hsa04742 | 0.94907387 |
59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.93266603 |
60 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.91960357 |
61 | Circadian rhythm_Homo sapiens_hsa04710 | 0.91706668 |
62 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.89490030 |
63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.88726336 |
64 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.86857267 |
65 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.85285640 |
66 | Galactose metabolism_Homo sapiens_hsa00052 | 0.84163690 |
67 | ABC transporters_Homo sapiens_hsa02010 | 0.83553082 |
68 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.81262081 |
69 | Bile secretion_Homo sapiens_hsa04976 | 0.80159919 |
70 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.79207631 |
71 | Insulin resistance_Homo sapiens_hsa04931 | 0.79093247 |
72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77028737 |
73 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.75292735 |
74 | Sulfur relay system_Homo sapiens_hsa04122 | 0.73516852 |
75 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.71374680 |
76 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.68612333 |
77 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.67680678 |
78 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.66977376 |
79 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.65154105 |
80 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.64694658 |
81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.62832208 |
82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.62156729 |
83 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.61094512 |
84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60488944 |
85 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.58858314 |
86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.57698512 |
87 | Histidine metabolism_Homo sapiens_hsa00340 | 0.56926493 |
88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54648931 |
89 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.54648830 |
90 | Legionellosis_Homo sapiens_hsa05134 | 0.54140319 |
91 | Proteasome_Homo sapiens_hsa03050 | 0.53198780 |
92 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.52632319 |
93 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.52221003 |
94 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.51223659 |
95 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48399851 |
96 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.47665273 |
97 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.46811720 |
98 | Prostate cancer_Homo sapiens_hsa05215 | 0.46688777 |
99 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.45800987 |
100 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.44924692 |
101 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.43892730 |
102 | Renin secretion_Homo sapiens_hsa04924 | 0.42591027 |
103 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.41882175 |
104 | Huntingtons disease_Homo sapiens_hsa05016 | 0.41118785 |
105 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.40800350 |
106 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.40477873 |
107 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.39884314 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.39687934 |
109 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.39378350 |
110 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.38398351 |
111 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.36711173 |
112 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.33458868 |
113 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.30051876 |
114 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.29932219 |
115 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.29568596 |
116 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.27303397 |
117 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.26118850 |
118 | Phagosome_Homo sapiens_hsa04145 | 0.26001526 |
119 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.24859962 |
120 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.24678037 |
121 | Hepatitis C_Homo sapiens_hsa05160 | 0.24467088 |
122 | Metabolic pathways_Homo sapiens_hsa01100 | 0.23196081 |
123 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.23087724 |
124 | Circadian entrainment_Homo sapiens_hsa04713 | 0.22915069 |
125 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.22194288 |
126 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.21828685 |
127 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.21696868 |
128 | Endometrial cancer_Homo sapiens_hsa05213 | 0.21474982 |
129 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.21220820 |
130 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.21191569 |
131 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.21159551 |
132 | Thyroid cancer_Homo sapiens_hsa05216 | 0.19546946 |
133 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.18877098 |
134 | Bladder cancer_Homo sapiens_hsa05219 | 0.16564499 |
135 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.15368090 |
136 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.14325779 |
137 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.13839737 |
138 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.13478135 |
139 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.13448066 |