TTI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)6.61083674
2nuclear pore complex assembly (GO:0051292)5.94617347
3transcription from mitochondrial promoter (GO:0006390)5.31795128
4replication fork processing (GO:0031297)5.29050858
5DNA deamination (GO:0045006)5.05112406
6telomere maintenance via semi-conservative replication (GO:0032201)4.98606927
7maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)4.87361899
8somatic diversification of immune receptors via somatic mutation (GO:0002566)4.84449283
9somatic hypermutation of immunoglobulin genes (GO:0016446)4.84449283
10embryonic process involved in female pregnancy (GO:0060136)4.84307292
11DNA strand elongation involved in DNA replication (GO:0006271)4.76459662
12proline metabolic process (GO:0006560)4.69094691
13formation of translation preinitiation complex (GO:0001731)4.59797929
14establishment of integrated proviral latency (GO:0075713)4.58912165
15DNA strand elongation (GO:0022616)4.55984573
16pore complex assembly (GO:0046931)4.52792214
17mitochondrial DNA metabolic process (GO:0032042)4.38915798
18protein localization to chromosome, centromeric region (GO:0071459)4.31831169
19nucleotide-excision repair, DNA gap filling (GO:0006297)4.31691250
20positive regulation of protein homooligomerization (GO:0032464)4.30313231
21telomere maintenance via recombination (GO:0000722)4.30253154
22DNA strand renaturation (GO:0000733)4.26127294
23heterochromatin organization (GO:0070828)4.25289477
24mitotic G1 DNA damage checkpoint (GO:0031571)4.25238038
25L-serine metabolic process (GO:0006563)4.13894321
26meiotic chromosome segregation (GO:0045132)4.09662493
27DNA unwinding involved in DNA replication (GO:0006268)4.08929858
28regulation of translational fidelity (GO:0006450)4.08265887
29chromatin remodeling at centromere (GO:0031055)4.00488922
30base-excision repair (GO:0006284)3.98468752
31mitotic recombination (GO:0006312)3.95994323
32mRNA cleavage (GO:0006379)3.88642834
33CENP-A containing nucleosome assembly (GO:0034080)3.87558339
34mitotic nuclear envelope disassembly (GO:0007077)3.86825784
35establishment of apical/basal cell polarity (GO:0035089)3.85353125
36viral mRNA export from host cell nucleus (GO:0046784)3.82471206
37negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.80571516
38mitotic sister chromatid segregation (GO:0000070)3.79754684
39mitotic sister chromatid cohesion (GO:0007064)3.79097619
40regulation of sister chromatid cohesion (GO:0007063)3.76049890
41poly(A)+ mRNA export from nucleus (GO:0016973)3.73042791
42telomere maintenance via telomere lengthening (GO:0010833)3.72584669
43positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.69669224
44positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.69669224
45positive regulation of mitotic sister chromatid separation (GO:1901970)3.69669224
46spliceosomal tri-snRNP complex assembly (GO:0000244)3.69151217
47regulation of RNA export from nucleus (GO:0046831)3.68495871
48positive regulation of chromosome segregation (GO:0051984)3.67243911
49purine nucleobase biosynthetic process (GO:0009113)3.64829392
50metaphase plate congression (GO:0051310)3.64703701
51regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.63401738
52mitotic G1/S transition checkpoint (GO:0044819)3.63110031
53oxidative demethylation (GO:0070989)3.62813431
54regulation of integrin activation (GO:0033623)3.61371169
55DNA replication initiation (GO:0006270)3.58805157
56nuclear envelope disassembly (GO:0051081)3.58516531
57membrane disassembly (GO:0030397)3.58516531
58dosage compensation (GO:0007549)3.54677455
59DNA replication-independent nucleosome organization (GO:0034724)3.54300069
60DNA replication-independent nucleosome assembly (GO:0006336)3.54300069
61G1 DNA damage checkpoint (GO:0044783)3.53957540
62regulation of double-strand break repair via homologous recombination (GO:0010569)3.52219297
63DNA topological change (GO:0006265)3.51376199
64regulation of centriole replication (GO:0046599)3.47941950
65regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.45037666
66sister chromatid segregation (GO:0000819)3.42345931
67establishment of viral latency (GO:0019043)3.41755375
68chromatin assembly or disassembly (GO:0006333)3.40633977
69regulation of protein homooligomerization (GO:0032462)3.38576397
70protein localization to kinetochore (GO:0034501)3.37278820
71chromatin assembly (GO:0031497)3.34819340
72termination of RNA polymerase II transcription (GO:0006369)3.34272002
73regulation of chromosome segregation (GO:0051983)3.33380765
74negative regulation of mRNA processing (GO:0050686)3.33300225
75spindle checkpoint (GO:0031577)3.32353084
76non-recombinational repair (GO:0000726)3.29592007
77double-strand break repair via nonhomologous end joining (GO:0006303)3.29592007
78maturation of SSU-rRNA (GO:0030490)3.29364278
79mitotic spindle checkpoint (GO:0071174)3.29157494
80chromosome segregation (GO:0007059)3.28656058
81IMP metabolic process (GO:0046040)3.27105843
82DNA duplex unwinding (GO:0032508)3.26065992
83DNA geometric change (GO:0032392)3.25064681
84cellular response to zinc ion (GO:0071294)3.23876974
85regulation of mitochondrial translation (GO:0070129)3.23548349
86maturation of 5.8S rRNA (GO:0000460)3.22406553
87negative regulation of mitotic sister chromatid separation (GO:2000816)3.20762274
88negative regulation of sister chromatid segregation (GO:0033046)3.20762274
89negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.20762274
90negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.20762274
91negative regulation of mitotic sister chromatid segregation (GO:0033048)3.20762274
92negative regulation of RNA splicing (GO:0033119)3.20463919
93kinetochore organization (GO:0051383)3.19723404
94regulation of spindle organization (GO:0090224)3.19388338
95establishment of monopolar cell polarity (GO:0061162)3.19258408
96establishment or maintenance of monopolar cell polarity (GO:0061339)3.19258408
97DNA conformation change (GO:0071103)3.18979625
98chromosome condensation (GO:0030261)3.17338105
99DNA replication checkpoint (GO:0000076)3.16194691
100regulation of double-strand break repair (GO:2000779)3.15698730
101kinetochore assembly (GO:0051382)3.15673226
102regulation of posttranscriptional gene silencing (GO:0060147)3.14787667
103regulation of gene silencing by miRNA (GO:0060964)3.14787667
104regulation of gene silencing by RNA (GO:0060966)3.14787667
105histone exchange (GO:0043486)3.14086723
106nuclear envelope organization (GO:0006998)3.12305235
107ribosome assembly (GO:0042255)3.11540834
108regulation of centrosome cycle (GO:0046605)3.11205402
109positive regulation of cell cycle checkpoint (GO:1901978)3.09971333
110regulation of mitotic metaphase/anaphase transition (GO:0030071)3.08110297
111regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.08110297
112mitochondrial RNA metabolic process (GO:0000959)3.07781558
113regulation of DNA damage checkpoint (GO:2000001)3.07727578
114mitotic spindle assembly checkpoint (GO:0007094)3.07635127
115establishment of protein localization to mitochondrial membrane (GO:0090151)3.06764812
116pre-miRNA processing (GO:0031054)3.05132325
117nuclear pore organization (GO:0006999)3.03224821
118negative regulation of cell cycle arrest (GO:0071157)3.02844122
119ATP-dependent chromatin remodeling (GO:0043044)3.02762743
120IMP biosynthetic process (GO:0006188)3.02090455
121mRNA export from nucleus (GO:0006406)3.01930445
122spindle assembly checkpoint (GO:0071173)3.01579938
123mitotic chromosome condensation (GO:0007076)3.01415647
124DNA double-strand break processing (GO:0000729)3.01316420
125DNA replication-dependent nucleosome organization (GO:0034723)2.99105788
126DNA replication-dependent nucleosome assembly (GO:0006335)2.99105788
127ribosomal small subunit assembly (GO:0000028)2.98859624
128mRNA transport (GO:0051028)2.98406381
129regulation of mitotic sister chromatid separation (GO:0010965)2.98303728
130regulation of mitotic sister chromatid segregation (GO:0033047)2.98303728
131regulation of sister chromatid segregation (GO:0033045)2.98303728
132resolution of meiotic recombination intermediates (GO:0000712)2.97648127
133establishment of chromosome localization (GO:0051303)2.96296611
134folic acid-containing compound biosynthetic process (GO:0009396)2.94552550
135base-excision repair, AP site formation (GO:0006285)2.94539481
136mitochondrial DNA replication (GO:0006264)2.92958009
137mitotic metaphase plate congression (GO:0007080)2.90615074
138telomere organization (GO:0032200)2.90604574
139RNA export from nucleus (GO:0006405)2.90533591
140DNA packaging (GO:0006323)2.90315292
141protein localization to chromosome (GO:0034502)2.89659882
142mismatch repair (GO:0006298)2.88372662
143embryonic placenta development (GO:0001892)2.87683761
144negative regulation of chromosome segregation (GO:0051985)2.86117890
145trophectodermal cell differentiation (GO:0001829)2.85221467
146negative regulation of mRNA metabolic process (GO:1903312)2.85156759
147DNA ligation (GO:0006266)2.84724988
148regulation of spindle checkpoint (GO:0090231)2.84720209
149pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.84486908
150nucleobase biosynthetic process (GO:0046112)2.83936065
151regulation of nucleobase-containing compound transport (GO:0032239)2.83136986

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.19479675
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.72355085
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.52717032
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.19812836
5E2F4_17652178_ChIP-ChIP_JURKAT_Human2.85306566
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.66127816
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.55415629
8MYC_18358816_ChIP-ChIP_MESCs_Mouse2.39304993
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.35692216
10MYC_22102868_ChIP-Seq_BL_Human2.17846498
11SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.15347540
12VDR_21846776_ChIP-Seq_THP-1_Human2.08305338
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.99265141
14ETS1_20019798_ChIP-Seq_JURKAT_Human1.89141198
15NELFA_20434984_ChIP-Seq_ESCs_Mouse1.87755074
16EST1_17652178_ChIP-ChIP_JURKAT_Human1.85174967
17DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.82179207
18E2F1_21310950_ChIP-Seq_MCF-7_Human1.79375478
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.78112287
20ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.77813493
21MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76868240
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.73023533
23E2F1_18555785_ChIP-Seq_MESCs_Mouse1.71819151
24XRN2_22483619_ChIP-Seq_HELA_Human1.71260999
25ELK1_19687146_ChIP-ChIP_HELA_Human1.69482216
26NANOG_18555785_ChIP-Seq_MESCs_Mouse1.65911115
27THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63536507
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63488367
29STAT3_1855785_ChIP-Seq_MESCs_Mouse1.60986350
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.60889525
31GABP_19822575_ChIP-Seq_HepG2_Human1.60204336
32CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.56503361
33EGR1_19374776_ChIP-ChIP_THP-1_Human1.56461984
34PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.55786189
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.54775246
36MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53419620
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52188006
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51898259
39DCP1A_22483619_ChIP-Seq_HELA_Human1.51050316
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.49990568
41KDM5A_27292631_Chip-Seq_BREAST_Human1.49775239
42VDR_23849224_ChIP-Seq_CD4+_Human1.49407815
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.49328093
44KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.48859156
45KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.48859156
46KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.48859156
47NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.47151681
48KLF4_18555785_ChIP-Seq_MESCs_Mouse1.46806560
49KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.46186168
50ELF1_17652178_ChIP-ChIP_JURKAT_Human1.46027710
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45336569
52KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.45214535
53AR_21909140_ChIP-Seq_LNCAP_Human1.43769389
54NANOG_21062744_ChIP-ChIP_HESCs_Human1.43053554
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.42714115
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.42428242
57MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.42256432
58TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41632951
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41584901
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.41362298
61CREB1_15753290_ChIP-ChIP_HEK293T_Human1.37588068
62E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.36494555
63TTF2_22483619_ChIP-Seq_HELA_Human1.34580199
64ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33610261
65RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.30326131
66FOXP3_21729870_ChIP-Seq_TREG_Human1.30103521
67NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.28429128
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28128708
69TFEB_21752829_ChIP-Seq_HELA_Human1.26317973
70SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.23598403
71NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.21519919
72CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.21486363
73BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.21123141
74STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19938178
75CIITA_25753668_ChIP-Seq_RAJI_Human1.18023417
76TCF3_18692474_ChIP-Seq_MEFs_Mouse1.17511720
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.17229221
78PU.1_20513432_ChIP-Seq_Bcells_Mouse1.16393960
79PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15419373
80TCF3_18692474_ChIP-Seq_MESCs_Mouse1.15383229
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15014081
82POU5F1_16518401_ChIP-PET_MESCs_Mouse1.14533077
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14137970
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13462962
85E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.12503414
86ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11856561
87YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.11314866
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11034344
89SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.07713403
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07477701
91SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06687087
92CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.06620701
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06438167
94MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05500577
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05293300
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01996214
97GATA1_22383799_ChIP-Seq_G1ME_Mouse1.01983022
98ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01748701
99SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00673135
100MYC_18940864_ChIP-ChIP_HL60_Human1.00519875
101SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00072737
102CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99592719
103TP63_19390658_ChIP-ChIP_HaCaT_Human0.99516897
104ZNF263_19887448_ChIP-Seq_K562_Human0.99121294
105SOX2_16153702_ChIP-ChIP_HESCs_Human0.98866928
106NANOG_16153702_ChIP-ChIP_HESCs_Human0.97940516
107HOXB4_20404135_ChIP-ChIP_EML_Mouse0.96455654
108ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95845615
109SRF_21415370_ChIP-Seq_HL-1_Mouse0.95578226
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95568315
111TCF7_22412390_ChIP-Seq_EML_Mouse0.94148781
112POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.93790074
113FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93616710
114KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93355809
115KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.93204546
116MAF_26560356_Chip-Seq_TH1_Human0.93129909
117ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92386899
118IRF1_19129219_ChIP-ChIP_H3396_Human0.92287828
119SOX17_20123909_ChIP-Seq_XEN_Mouse0.92208538
120UTX_26944678_Chip-Seq_JUKART_Human0.92063764
121CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90298633
122GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.84935606
123HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.83518225
124CHD1_26751641_Chip-Seq_LNCaP_Human0.79372121
125SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.77385319
126TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.77363479
127TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75509340
128SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.71418774
129CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.71357933
130TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.70291644

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.47181214
2MP0010094_abnormal_chromosome_stability4.18153682
3MP0009278_abnormal_bone_marrow3.77663281
4MP0004957_abnormal_blastocyst_morpholog3.45065443
5MP0003693_abnormal_embryo_hatching3.42782696
6MP0003111_abnormal_nucleus_morphology3.19810075
7MP0003077_abnormal_cell_cycle3.02353390
8MP0006292_abnormal_olfactory_placode2.77180556
9MP0008877_abnormal_DNA_methylation2.65292853
10MP0008058_abnormal_DNA_repair2.62271198
11MP0001545_abnormal_hematopoietic_system2.44433361
12MP0005397_hematopoietic_system_phenotyp2.44433361
13MP0004233_abnormal_muscle_weight2.40164584
14MP0010352_gastrointestinal_tract_polyps2.31256806
15MP0008932_abnormal_embryonic_tissue2.01741292
16MP0010030_abnormal_orbit_morphology2.00006771
17MP0001730_embryonic_growth_arrest1.96845302
18MP0000350_abnormal_cell_proliferation1.94266507
19MP0002009_preneoplasia1.91801040
20MP0009697_abnormal_copulation1.88352154
21MP0001697_abnormal_embryo_size1.88107145
22MP0003890_abnormal_embryonic-extraembry1.83870705
23MP0003786_premature_aging1.80104004
24MP0003567_abnormal_fetal_cardiomyocyte1.79925623
25MP0004264_abnormal_extraembryonic_tissu1.79314237
26MP0003136_yellow_coat_color1.77474346
27MP0001672_abnormal_embryogenesis/_devel1.75726589
28MP0005380_embryogenesis_phenotype1.75726589
29MP0002086_abnormal_extraembryonic_tissu1.75552218
30MP0003123_paternal_imprinting1.74811647
31MP0002396_abnormal_hematopoietic_system1.73493137
32MP0002084_abnormal_developmental_patter1.73028931
33MP0003941_abnormal_skin_development1.70416095
34MP0000490_abnormal_crypts_of1.68733854
35MP0010307_abnormal_tumor_latency1.68186595
36MP0005076_abnormal_cell_differentiation1.67684529
37MP0002085_abnormal_embryonic_tissue1.62060773
38MP0009672_abnormal_birth_weight1.61885344
39MP0003984_embryonic_growth_retardation1.56976614
40MP0002088_abnormal_embryonic_growth/wei1.51978294
41MP0003121_genomic_imprinting1.50689981
42MP0005171_absent_coat_pigmentation1.49981340
43MP0008007_abnormal_cellular_replicative1.49535177
44MP0002080_prenatal_lethality1.48950774
45MP0002019_abnormal_tumor_incidence1.47333054
46MP0004197_abnormal_fetal_growth/weight/1.45935393
47MP0002163_abnormal_gland_morphology1.45479583
48MP0002697_abnormal_eye_size1.43748691
49MP0005174_abnormal_tail_pigmentation1.42387499
50MP0001286_abnormal_eye_development1.39811051
51MP0002653_abnormal_ependyma_morphology1.37174874
52MP0003122_maternal_imprinting1.35345236
53MP0003119_abnormal_digestive_system1.34243064
54MP0003937_abnormal_limbs/digits/tail_de1.33068548
55MP0001293_anophthalmia1.31781758
56MP0008995_early_reproductive_senescence1.31703486
57MP0000313_abnormal_cell_death1.31161146
58MP0003221_abnormal_cardiomyocyte_apopto1.29825547
59MP0002269_muscular_atrophy1.27839399
60MP0002938_white_spotting1.25823926
61MP0004185_abnormal_adipocyte_glucose1.24418991
62MP0004133_heterotaxia1.23138541
63MP0003283_abnormal_digestive_organ1.21321693
64MP0006035_abnormal_mitochondrial_morpho1.19613848
65MP0002092_abnormal_eye_morphology1.18355820
66MP0006072_abnormal_retinal_apoptosis1.17255429
67MP0002233_abnormal_nose_morphology1.14900309
68MP0000371_diluted_coat_color1.13161053
69MP0004808_abnormal_hematopoietic_stem1.07963796
70MP0003172_abnormal_lysosome_physiology1.07226481
71MP0000689_abnormal_spleen_morphology1.06217070
72MP0000372_irregular_coat_pigmentation1.04617538
73MP0001661_extended_life_span1.03099897
74MP0003763_abnormal_thymus_physiology1.02839271
75MP0001145_abnormal_male_reproductive1.02183515
76MP0000566_synostosis1.00422179
77MP0008789_abnormal_olfactory_epithelium1.00280745
78MP0000685_abnormal_immune_system0.99296703
79MP0002398_abnormal_bone_marrow0.98859871
80MP0003942_abnormal_urinary_system0.98760845
81MP0000537_abnormal_urethra_morphology0.98270852
82MP0009333_abnormal_splenocyte_physiolog0.96692231
83MP0000703_abnormal_thymus_morphology0.96679387
84MP0002210_abnormal_sex_determination0.95377068
85MP0003718_maternal_effect0.94503426
86MP0003806_abnormal_nucleotide_metabolis0.94044665
87MP0005075_abnormal_melanosome_morpholog0.93652993
88MP0003861_abnormal_nervous_system0.93596714
89MP0005408_hypopigmentation0.91850388
90MP0002722_abnormal_immune_system0.90472898
91MP0000579_abnormal_nail_morphology0.89515138
92MP0005058_abnormal_lysosome_morphology0.89444159
93MP0003453_abnormal_keratinocyte_physiol0.88975799
94MP0000428_abnormal_craniofacial_morphol0.88377384
95MP0001529_abnormal_vocalization0.86451435
96MP0005083_abnormal_biliary_tract0.86275230
97MP0005394_taste/olfaction_phenotype0.86230975
98MP0005499_abnormal_olfactory_system0.86230975
99MP0010630_abnormal_cardiac_muscle0.86079374
100MP0001929_abnormal_gametogenesis0.85396406
101MP0005266_abnormal_metabolism0.84655639
102MP0003315_abnormal_perineum_morphology0.84399357
103MP0000613_abnormal_salivary_gland0.83421588
104MP0003755_abnormal_palate_morphology0.83281282
105MP0005023_abnormal_wound_healing0.82997273
106MP0002075_abnormal_coat/hair_pigmentati0.82908826
107MP0000647_abnormal_sebaceous_gland0.82437802
108MP0000653_abnormal_sex_gland0.81868582
109MP0002111_abnormal_tail_morphology0.81659744
110MP0005384_cellular_phenotype0.80620941
111MP0002282_abnormal_trachea_morphology0.80412190
112MP0002166_altered_tumor_susceptibility0.80356433
113MP0003385_abnormal_body_wall0.79018952
114MP0002405_respiratory_system_inflammati0.78207184
115MP0001346_abnormal_lacrimal_gland0.76823119
116MP0003656_abnormal_erythrocyte_physiolo0.76437905
117MP0003566_abnormal_cell_adhesion0.76359613
118MP0002132_abnormal_respiratory_system0.76141391
119MP0000015_abnormal_ear_pigmentation0.75078197
120MP0002877_abnormal_melanocyte_morpholog0.75002282
121MP0004147_increased_porphyrin_level0.73279029
122MP0000470_abnormal_stomach_morphology0.73262302
123MP0002429_abnormal_blood_cell0.72051319
124MP0003699_abnormal_female_reproductive0.71503993
125MP0003787_abnormal_imprinting0.70670914
126MP0002006_tumorigenesis0.70106870
127MP0002234_abnormal_pharynx_morphology0.68420262
128MP0001915_intracranial_hemorrhage0.68282358
129MP0002249_abnormal_larynx_morphology0.67871594
130MP0002089_abnormal_postnatal_growth/wei0.67032729
131MP0003950_abnormal_plasma_membrane0.66687782
132MP0000477_abnormal_intestine_morphology0.66236628
133MP0000049_abnormal_middle_ear0.66173546
134MP0001873_stomach_inflammation0.65605944
135MP0003935_abnormal_craniofacial_develop0.64991295
136MP0003186_abnormal_redox_activity0.64630395
137MP0005330_cardiomyopathy0.64102354
138MP0003705_abnormal_hypodermis_morpholog0.63853391
139MP0005621_abnormal_cell_physiology0.63535835
140MP0003828_pulmonary_edema0.63449012
141MP0000432_abnormal_head_morphology0.63287455
142MP0003943_abnormal_hepatobiliary_system0.62441189
143MP0001186_pigmentation_phenotype0.62121231
144MP0009703_decreased_birth_body0.61967234
145MP0000358_abnormal_cell_content/0.61070366
146MP0000266_abnormal_heart_morphology0.61051611
147MP0000716_abnormal_immune_system0.60902903
148MP0001119_abnormal_female_reproductive0.60359876
149MP0002925_abnormal_cardiovascular_devel0.60034933

Predicted human phenotypes

RankGene SetZ-score
1Rib fusion (HP:0000902)4.46666262
2Facial hemangioma (HP:0000329)4.35363154
3Poikiloderma (HP:0001029)4.08384815
4Pustule (HP:0200039)3.85695561
5Meckel diverticulum (HP:0002245)3.66855801
6Rectovaginal fistula (HP:0000143)3.53643476
7Rectal fistula (HP:0100590)3.53643476
8Basal cell carcinoma (HP:0002671)3.53083416
9Abnormality of the preputium (HP:0100587)3.46830667
10Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.42845969
11Intestinal fistula (HP:0100819)3.39702111
12Selective tooth agenesis (HP:0001592)3.39539917
13Tongue fasciculations (HP:0001308)3.38238015
14Absent thumb (HP:0009777)3.36873074
15Annular pancreas (HP:0001734)3.30992219
16Short humerus (HP:0005792)3.30913439
17Aplasia/hypoplasia of the humerus (HP:0006507)3.27311732
18Nephroblastoma (Wilms tumor) (HP:0002667)3.25938715
19Volvulus (HP:0002580)3.24434423
20Hypochromic microcytic anemia (HP:0004840)3.19465461
21Ulnar bowing (HP:0003031)3.18842254
22Patellar aplasia (HP:0006443)3.17466889
23Vaginal fistula (HP:0004320)3.16144555
24Male infertility (HP:0003251)3.15900758
25Muscle fibrillation (HP:0010546)3.14354463
26Squamous cell carcinoma (HP:0002860)3.11172833
27Absent radius (HP:0003974)3.10191828
28Intestinal atresia (HP:0011100)3.07839312
29Small intestinal stenosis (HP:0012848)3.07701447
30Duodenal stenosis (HP:0100867)3.07701447
31Embryonal renal neoplasm (HP:0011794)3.05140836
32Orthostatic hypotension (HP:0001278)3.04190654
33Concave nail (HP:0001598)3.01996506
34Ependymoma (HP:0002888)2.98553641
35Broad alveolar ridges (HP:0000187)2.91062409
36Microvesicular hepatic steatosis (HP:0001414)2.87287692
37Aplasia/Hypoplasia of the patella (HP:0006498)2.87060090
38Aplasia involving forearm bones (HP:0009822)2.86216595
39Absent forearm bone (HP:0003953)2.86216595
40Abnormal lung lobation (HP:0002101)2.83222225
41Premature graying of hair (HP:0002216)2.78716950
42Vertebral hypoplasia (HP:0008417)2.72292406
43Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.72292406
44Increased nuchal translucency (HP:0010880)2.70096375
4511 pairs of ribs (HP:0000878)2.70006305
46Birth length less than 3rd percentile (HP:0003561)2.67894801
47Ectopic kidney (HP:0000086)2.65143919
48Degeneration of anterior horn cells (HP:0002398)2.61749081
49Abnormality of the anterior horn cell (HP:0006802)2.61749081
50Large for gestational age (HP:0001520)2.61202801
51Abnormality of the astrocytes (HP:0100707)2.60824439
52Astrocytoma (HP:0009592)2.60824439
53Pancreatic islet-cell hyperplasia (HP:0004510)2.60058243
54Spinal muscular atrophy (HP:0007269)2.59004229
55High anterior hairline (HP:0009890)2.56335435
56Abnormality of the duodenum (HP:0002246)2.53668661
57Increased IgM level (HP:0003496)2.52494792
58Abnormality of the carotid arteries (HP:0005344)2.52133914
59Multiple enchondromatosis (HP:0005701)2.49000260
60Acute lymphatic leukemia (HP:0006721)2.47734056
61Medulloblastoma (HP:0002885)2.46649082
62Turricephaly (HP:0000262)2.45924996
63Chromsome breakage (HP:0040012)2.45295296
64Abnormality of the ileum (HP:0001549)2.44208011
65Abnormality of DNA repair (HP:0003254)2.43503462
66Albinism (HP:0001022)2.43077481
67Colon cancer (HP:0003003)2.43014255
68Diastasis recti (HP:0001540)2.40478112
69Myelodysplasia (HP:0002863)2.40308180
70Alopecia of scalp (HP:0002293)2.39601935
71Neoplasm of the oral cavity (HP:0100649)2.38113084
72Congenital hip dislocation (HP:0001374)2.37888740
73Rhabdomyosarcoma (HP:0002859)2.37594862
74Sloping forehead (HP:0000340)2.35919176
75Anteriorly placed anus (HP:0001545)2.35421421
76Horseshoe kidney (HP:0000085)2.35098477
77Missing ribs (HP:0000921)2.34065134
78Cortical dysplasia (HP:0002539)2.33310207
79Abnormality of male internal genitalia (HP:0000022)2.33096972
80Breast hypoplasia (HP:0003187)2.32724985
81Hypoplasia of the capital femoral epiphysis (HP:0003090)2.31858841
82Abnormality of glycolysis (HP:0004366)2.31758377
83Abnormality of the labia minora (HP:0012880)2.29700380
84IgA deficiency (HP:0002720)2.29184005
85Short chin (HP:0000331)2.27215125
86Abnormality of cells of the erythroid lineage (HP:0012130)2.27101432
87Hyperglycinemia (HP:0002154)2.25367280
88Aplasia/Hypoplasia of the sternum (HP:0006714)2.25218480
89Duplication of thumb phalanx (HP:0009942)2.24852530
90Abnormal hemoglobin (HP:0011902)2.24702221
91Abnormal number of incisors (HP:0011064)2.21367328
92Dysautonomia (HP:0002459)2.20154216
93Chromosomal breakage induced by crosslinking agents (HP:0003221)2.19605435
94Microglossia (HP:0000171)2.19464640
95Premature skin wrinkling (HP:0100678)2.19345547
96Abnormality of cochlea (HP:0000375)2.19056461
97Glioma (HP:0009733)2.18981311
98Hypochromic anemia (HP:0001931)2.18191077
99Type I transferrin isoform profile (HP:0003642)2.13102303
100Triphalangeal thumb (HP:0001199)2.11809846
101Abnormality of reticulocytes (HP:0004312)2.11469127
102Facial cleft (HP:0002006)2.11168539
103Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.10807996
104Absent epiphyses (HP:0010577)2.10807996
105Hepatoblastoma (HP:0002884)2.09999126
106Overlapping toe (HP:0001845)2.07621237
107Abnormal number of erythroid precursors (HP:0012131)2.06440405
108Agnosia (HP:0010524)2.03454896
109Abnormality of chromosome stability (HP:0003220)2.03411699
110Short thumb (HP:0009778)2.02061645
111Clubbing of toes (HP:0100760)2.01877609
112Cerebral aneurysm (HP:0004944)2.00036395
113Shawl scrotum (HP:0000049)1.99406864
114Abnormality of lateral ventricle (HP:0030047)1.99362298
115Choanal atresia (HP:0000453)1.99349871
116Cafe-au-lait spot (HP:0000957)1.99126463
117Mucopolysacchariduria (HP:0008155)1.98315857
118Urinary glycosaminoglycan excretion (HP:0003541)1.98315857
119Polycythemia (HP:0001901)1.98176368
120Increased serum pyruvate (HP:0003542)1.97343706
121Lymphoma (HP:0002665)1.93629477
122Short 5th finger (HP:0009237)1.93615516
123Asymmetric septal hypertrophy (HP:0001670)1.93099447
124Prominent nose (HP:0000448)1.92485172
125Duplicated collecting system (HP:0000081)1.90063300
126Neoplasm of the adrenal cortex (HP:0100641)1.89399113
127Abnormality of endocrine pancreas physiology (HP:0012093)1.89009002
128Abnormality of the pancreatic islet cells (HP:0006476)1.89009002
129Capillary hemangiomas (HP:0005306)1.88759684
130Abnormality of the fingertips (HP:0001211)1.87987871
131Vertebral fusion (HP:0002948)1.87721168
132Atresia of the external auditory canal (HP:0000413)1.87408923
133Reticulocytopenia (HP:0001896)1.87233113
134Hypotelorism (HP:0000601)1.86814012
135Macrocytic anemia (HP:0001972)1.86698374
136Hypoplasia of the radius (HP:0002984)1.85646436
137Abnormality of T cell physiology (HP:0011840)1.85442440
138Neoplasm of striated muscle (HP:0009728)1.84977970
139Gastrointestinal atresia (HP:0002589)1.84390959
140Spastic diplegia (HP:0001264)1.83497869
141Bifid tongue (HP:0010297)1.83335479
142Aplasia/Hypoplasia of the uvula (HP:0010293)1.82942801
143Joint stiffness (HP:0001387)1.81568598
144Embryonal neoplasm (HP:0002898)1.80467876
145Hyperglycinuria (HP:0003108)1.80223502
146Abnormality of the aortic arch (HP:0012303)1.80169785
147Dysostosis multiplex (HP:0000943)1.78547636
148Progressive external ophthalmoplegia (HP:0000590)1.78501130
149Oral leukoplakia (HP:0002745)1.78028406
150Cholecystitis (HP:0001082)1.78005748
151Abnormal gallbladder physiology (HP:0012438)1.78005748
152Abnormality of the calcaneus (HP:0008364)1.73721109
153Abnormal protein glycosylation (HP:0012346)1.73194948
154Abnormal glycosylation (HP:0012345)1.73194948
155Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.73194948
156Abnormal protein N-linked glycosylation (HP:0012347)1.73194948
157Reduced antithrombin III activity (HP:0001976)1.72365610
158Cleft eyelid (HP:0000625)1.71850624
159Hypoplastic pelvis (HP:0008839)1.71703655
160Proximal placement of thumb (HP:0009623)1.68200123
161Aplasia/Hypoplasia of the sacrum (HP:0008517)1.64917375
162Premature ovarian failure (HP:0008209)1.64455555
163Progressive muscle weakness (HP:0003323)1.64287744
164Secondary amenorrhea (HP:0000869)1.63834231
165Bone marrow hypocellularity (HP:0005528)1.63001170
166Abnormality of glycine metabolism (HP:0010895)1.62189079
167Abnormality of serine family amino acid metabolism (HP:0010894)1.62189079
168Impulsivity (HP:0100710)1.59931269
169Tracheoesophageal fistula (HP:0002575)1.59164341
170Arteriovenous malformation (HP:0100026)1.58724396
171Deep philtrum (HP:0002002)1.58415188
172Anophthalmia (HP:0000528)1.57370104

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K64.87091276
2ICK4.47129255
3CDC73.18501007
4MAPK153.10109885
5DDR22.77677558
6VRK22.71670204
7PBK2.50415715
8WEE12.47756374
9TAF12.47048021
10MAP3K112.46368765
11CDK72.15600703
12MATK2.07286747
13ZAK2.05839989
14PLK32.05648824
15SMG11.97041402
16TYRO31.89960254
17PINK11.86754709
18NEK21.83356985
19DAPK11.80729755
20CDK121.80191381
21BUB11.78162650
22MAP3K101.78060881
23MKNK11.76773969
24FGR1.76101602
25PRKD21.65049033
26NME21.62252940
27CSK1.61402896
28NEK11.59434336
29PLK11.57794400
30DYRK31.55976327
31NUAK11.52500436
32UHMK11.51921476
33DYRK1B1.51909036
34CDK61.51184233
35EEF2K1.50235959
36RPS6KB21.49515654
37PDK21.49133443
38PIM11.47757248
39ATR1.45090925
40CHEK21.44435320
41BRSK21.42614021
42PDGFRA1.41195375
43YES11.34718042
44MAP4K11.31296870
45TTK1.30900060
46PIM21.26540247
47BMX1.23435032
48MAP2K31.22576319
49STK101.14700314
50STK161.10196561
51TRPM71.09936579
52EIF2AK31.08372530
53AKT31.06916535
54AURKB1.04159806
55FLT31.00044814
56RPS6KC10.99559178
57RPS6KL10.99559178
58PASK0.98057183
59MAPK110.97833273
60CDK40.97396951
61EIF2AK20.96491328
62ACVR1B0.95912250
63CHEK10.95887955
64NME10.94514710
65TRIB30.92475036
66BRSK10.86572314
67RPS6KA60.86447731
68MTOR0.85432523
69MKNK20.84669410
70MAP3K80.84166885
71CDK20.81810217
72RPS6KA40.77581979
73PKN20.77052497
74MST1R0.76455721
75BRD40.74051057
76STK30.73597060
77CLK10.71969215
78ATM0.70992510
79AURKA0.70906721
80PLK40.70447779
81STK40.69083067
82MAPKAPK30.68107122
83PAK40.67818951
84ZAP700.67235892
85SCYL20.66607040
86PRKDC0.66448554
87EIF2AK10.66316836
88CDC42BPA0.65476723
89BRAF0.65431311
90LATS20.65360475
91MELK0.64332946
92CAMK1D0.60577848
93HIPK20.60301714
94TSSK60.60127996
95RPS6KA10.59779359
96VRK10.58775268
97STK38L0.58429537
98GSK3A0.56435957
99FGFR10.55423705
100RAF10.54146448
101PRKAA10.53698681
102IRAK30.52406633
103CSNK2A10.52006600
104BCR0.51670649
105LATS10.51622868
106CSNK1E0.51556921
107ERBB40.50272081
108CDK80.49831381
109CDK10.48366401
110EPHA20.47160179
111CSNK2A20.46923460
112RPS6KB10.46598298
113MET0.45964832
114BCKDK0.45961987
115TRIM280.44275522
116SRPK10.43049159
117MAPKAPK50.42144769
118MST40.41649697
119ALK0.40878610
120LYN0.40440431
121TGFBR10.39515264
122DYRK20.38603548
123RIPK10.37351398
124CCNB10.35791365
125CDK180.34579068
126MAPK10.34416666
127CDK150.34383623
128BTK0.34083960
129MAPK140.33808120
130STK240.33611061
131TESK20.32640698
132GSK3B0.32192704
133CAMK1G0.32065583
134CDK140.31785971
135MAP3K40.31492146
136WNK40.31154352
137LRRK20.30348573
138AKT10.30343587
139CDK11A0.29680537
140KSR10.29455401
141MAPK30.29312669
142CSNK1G30.28614215
143CDK30.28286128
144TLK10.28160213
145PHKG20.27803204
146PHKG10.27803204
147CSNK1G10.27582575
148PRKCI0.27573471
149AKT20.26520925

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.31112411
2Mismatch repair_Homo sapiens_hsa034305.30926422
3Base excision repair_Homo sapiens_hsa034104.42813001
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.06063189
5Homologous recombination_Homo sapiens_hsa034402.91232084
6RNA transport_Homo sapiens_hsa030132.87033872
7Spliceosome_Homo sapiens_hsa030402.81608474
8Nucleotide excision repair_Homo sapiens_hsa034202.78411244
9Cell cycle_Homo sapiens_hsa041102.57895494
10Fatty acid biosynthesis_Homo sapiens_hsa000612.26738486
11Fanconi anemia pathway_Homo sapiens_hsa034602.13286976
12mRNA surveillance pathway_Homo sapiens_hsa030152.02246383
13One carbon pool by folate_Homo sapiens_hsa006701.80430162
14p53 signaling pathway_Homo sapiens_hsa041151.72992268
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.60469822
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.59762098
17Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.59180216
18Biosynthesis of amino acids_Homo sapiens_hsa012301.57483634
19Ribosome_Homo sapiens_hsa030101.55330685
20RNA degradation_Homo sapiens_hsa030181.48113087
21mTOR signaling pathway_Homo sapiens_hsa041501.41580118
22Pyruvate metabolism_Homo sapiens_hsa006201.41315056
23RNA polymerase_Homo sapiens_hsa030201.39235589
24Non-homologous end-joining_Homo sapiens_hsa034501.37493719
25Pyrimidine metabolism_Homo sapiens_hsa002401.35738501
26Steroid biosynthesis_Homo sapiens_hsa001001.34048589
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.32481453
28Propanoate metabolism_Homo sapiens_hsa006401.32479077
29Proteasome_Homo sapiens_hsa030501.27684527
30Notch signaling pathway_Homo sapiens_hsa043301.25439755
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.22684668
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12402247
33Basal transcription factors_Homo sapiens_hsa030221.09375484
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08182110
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.07666289
36Lysine degradation_Homo sapiens_hsa003101.06687367
37Oocyte meiosis_Homo sapiens_hsa041141.04551532
38Sulfur relay system_Homo sapiens_hsa041221.03503256
39Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02252092
40Folate biosynthesis_Homo sapiens_hsa007900.99729768
41Primary immunodeficiency_Homo sapiens_hsa053400.97848523
42Epstein-Barr virus infection_Homo sapiens_hsa051690.92234945
43Hippo signaling pathway_Homo sapiens_hsa043900.91939400
44Viral carcinogenesis_Homo sapiens_hsa052030.91820610
45Fatty acid elongation_Homo sapiens_hsa000620.89420399
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89272649
47Shigellosis_Homo sapiens_hsa051310.88247472
48Fructose and mannose metabolism_Homo sapiens_hsa000510.84621351
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.84602693
50Circadian rhythm_Homo sapiens_hsa047100.81080568
51Legionellosis_Homo sapiens_hsa051340.81009882
52Adherens junction_Homo sapiens_hsa045200.80868341
53Herpes simplex infection_Homo sapiens_hsa051680.80827515
54Bladder cancer_Homo sapiens_hsa052190.78810108
55Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78519888
56MicroRNAs in cancer_Homo sapiens_hsa052060.77976756
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77248479
58Colorectal cancer_Homo sapiens_hsa052100.74548217
59Thyroid cancer_Homo sapiens_hsa052160.73391519
60Chronic myeloid leukemia_Homo sapiens_hsa052200.73296605
61Cysteine and methionine metabolism_Homo sapiens_hsa002700.72618305
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71866359
63Hedgehog signaling pathway_Homo sapiens_hsa043400.70330618
64Arginine and proline metabolism_Homo sapiens_hsa003300.69324902
65TGF-beta signaling pathway_Homo sapiens_hsa043500.68150636
66Small cell lung cancer_Homo sapiens_hsa052220.67457318
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.67264680
68Pentose phosphate pathway_Homo sapiens_hsa000300.66315689
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.65946619
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65849658
71Viral myocarditis_Homo sapiens_hsa054160.64996200
72HTLV-I infection_Homo sapiens_hsa051660.63354322
73Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.63073881
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.62709581
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62655517
76Selenocompound metabolism_Homo sapiens_hsa004500.59038251
77Fatty acid metabolism_Homo sapiens_hsa012120.58350883
78Carbon metabolism_Homo sapiens_hsa012000.56001742
79Antigen processing and presentation_Homo sapiens_hsa046120.55191560
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54539894
81VEGF signaling pathway_Homo sapiens_hsa043700.53989558
82Galactose metabolism_Homo sapiens_hsa000520.52133162
83Central carbon metabolism in cancer_Homo sapiens_hsa052300.51544009
84Acute myeloid leukemia_Homo sapiens_hsa052210.51505821
85Systemic lupus erythematosus_Homo sapiens_hsa053220.51313285
86N-Glycan biosynthesis_Homo sapiens_hsa005100.50381557
87Protein export_Homo sapiens_hsa030600.50180364
88Alcoholism_Homo sapiens_hsa050340.50158782
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49143833
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48545346
91Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48274409
92Purine metabolism_Homo sapiens_hsa002300.47066748
93Metabolic pathways_Homo sapiens_hsa011000.46776761
94AMPK signaling pathway_Homo sapiens_hsa041520.43719882
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.42175972
96B cell receptor signaling pathway_Homo sapiens_hsa046620.40659312
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.40354367
98Hepatitis B_Homo sapiens_hsa051610.40238892
99Huntingtons disease_Homo sapiens_hsa050160.40035564
100Basal cell carcinoma_Homo sapiens_hsa052170.38758530
101Apoptosis_Homo sapiens_hsa042100.36371396
102Insulin signaling pathway_Homo sapiens_hsa049100.34922627
103Wnt signaling pathway_Homo sapiens_hsa043100.34485463
104Measles_Homo sapiens_hsa051620.33360995
105Pancreatic cancer_Homo sapiens_hsa052120.31829678
106Fatty acid degradation_Homo sapiens_hsa000710.30949100
107Parkinsons disease_Homo sapiens_hsa050120.30093369
108Vitamin B6 metabolism_Homo sapiens_hsa007500.29924404
109HIF-1 signaling pathway_Homo sapiens_hsa040660.28081373
110Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.27505957
111Non-small cell lung cancer_Homo sapiens_hsa052230.26818650
112Drug metabolism - other enzymes_Homo sapiens_hsa009830.25951342
113Cyanoamino acid metabolism_Homo sapiens_hsa004600.24992619
114Prostate cancer_Homo sapiens_hsa052150.24260456
115Butanoate metabolism_Homo sapiens_hsa006500.24205008
116Glutathione metabolism_Homo sapiens_hsa004800.22561802
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.22542124
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.22351597
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21675046
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.21188412
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.20474442
122Endometrial cancer_Homo sapiens_hsa052130.20199955
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.20028402
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.18321878
125Peroxisome_Homo sapiens_hsa041460.16569141
126Arginine biosynthesis_Homo sapiens_hsa002200.14208414
127Pathways in cancer_Homo sapiens_hsa052000.07915382

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