TTLL4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.01291539
2nuclear pore organization (GO:0006999)5.81520376
3pre-miRNA processing (GO:0031054)5.33867577
4mitotic sister chromatid cohesion (GO:0007064)4.77844885
5DNA unwinding involved in DNA replication (GO:0006268)4.76806687
6protein localization to kinetochore (GO:0034501)4.61900576
7pore complex assembly (GO:0046931)4.40397562
8mitotic chromosome condensation (GO:0007076)4.28801690
9mitotic nuclear envelope disassembly (GO:0007077)4.16670768
10regulation of histone H3-K9 methylation (GO:0051570)4.08666022
11protein localization to chromosome, centromeric region (GO:0071459)4.08323727
12paraxial mesoderm development (GO:0048339)4.05744342
13regulation of RNA export from nucleus (GO:0046831)3.99631460
14sister chromatid segregation (GO:0000819)3.98811714
15DNA replication-dependent nucleosome assembly (GO:0006335)3.98225897
16DNA replication-dependent nucleosome organization (GO:0034723)3.98225897
17negative regulation of histone methylation (GO:0031061)3.91892386
18heterochromatin organization (GO:0070828)3.90371094
19nuclear envelope disassembly (GO:0051081)3.89075463
20membrane disassembly (GO:0030397)3.89075463
21DNA duplex unwinding (GO:0032508)3.83609751
22DNA geometric change (GO:0032392)3.83299877
23mitotic sister chromatid segregation (GO:0000070)3.76028218
24regulation of sister chromatid cohesion (GO:0007063)3.75037720
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.74311520
26chromatin assembly (GO:0031497)3.73272517
27positive regulation of hormone biosynthetic process (GO:0046886)3.72802291
28regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.68332912
29folic acid-containing compound biosynthetic process (GO:0009396)3.62983045
30regulation of gene silencing by RNA (GO:0060966)3.60955049
31regulation of posttranscriptional gene silencing (GO:0060147)3.60955049
32regulation of gene silencing by miRNA (GO:0060964)3.60955049
33telomere maintenance via semi-conservative replication (GO:0032201)3.56417382
34RNA stabilization (GO:0043489)3.49855264
35mRNA stabilization (GO:0048255)3.49855264
36mitotic metaphase plate congression (GO:0007080)3.47905282
37regulation of centriole replication (GO:0046599)3.43843585
38regulation of spindle organization (GO:0090224)3.40002728
39chromosome condensation (GO:0030261)3.38311242
40kinetochore organization (GO:0051383)3.37788518
41histone H2A monoubiquitination (GO:0035518)3.37746991
42negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.37453118
43metaphase plate congression (GO:0051310)3.37065747
44peptidyl-lysine dimethylation (GO:0018027)3.35369037
45DNA replication initiation (GO:0006270)3.35106430
46positive regulation of chromosome segregation (GO:0051984)3.33796643
47positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.33388776
48positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.33388776
49positive regulation of mitotic sister chromatid separation (GO:1901970)3.33388776
50DNA conformation change (GO:0071103)3.32335559
51regulation of translational fidelity (GO:0006450)3.31435867
52protein complex localization (GO:0031503)3.30978437
53IMP biosynthetic process (GO:0006188)3.28771222
54chromatin assembly or disassembly (GO:0006333)3.26256504
55L-serine metabolic process (GO:0006563)3.25867747
56gene silencing by RNA (GO:0031047)3.23271018
57regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.20647681
58monoubiquitinated protein deubiquitination (GO:0035520)3.19994647
59DNA packaging (GO:0006323)3.15587901
60protein localization to chromosome (GO:0034502)3.15064715
61negative regulation of DNA repair (GO:0045738)3.14766911
62telomere maintenance via recombination (GO:0000722)3.14588173
63regulation of DNA methylation (GO:0044030)3.13826753
64regulation of centrosome cycle (GO:0046605)3.12157913
65regulation of mitotic spindle organization (GO:0060236)3.11890816
66mRNA cleavage (GO:0006379)3.09660749
67dosage compensation (GO:0007549)3.09463705
68translesion synthesis (GO:0019985)3.05936303
69regulation of chromosome segregation (GO:0051983)3.05887265
70regulation of nucleobase-containing compound transport (GO:0032239)3.04948051
71nuclear envelope organization (GO:0006998)3.03868629
72negative regulation of mRNA processing (GO:0050686)3.02626095
73glucocorticoid receptor signaling pathway (GO:0042921)3.00579194
74cellular protein complex localization (GO:0034629)3.00376609
75negative regulation of RNA splicing (GO:0033119)2.98894155
76regulation of DNA damage checkpoint (GO:2000001)2.98526233
77histone H3-K36 demethylation (GO:0070544)2.98216057
78regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.97152452
79mitotic recombination (GO:0006312)2.96771894
80gene silencing (GO:0016458)2.96488639
81NLS-bearing protein import into nucleus (GO:0006607)2.96291931
82spliceosomal tri-snRNP complex assembly (GO:0000244)2.96159782
83mRNA transport (GO:0051028)2.94653949
84negative regulation of mRNA metabolic process (GO:1903312)2.93561442
85meiotic chromosome segregation (GO:0045132)2.93324631
86DNA strand elongation involved in DNA replication (GO:0006271)2.92374426
87negative regulation of chromosome segregation (GO:0051985)2.91130844
88protein export from nucleus (GO:0006611)2.90842679
89IMP metabolic process (GO:0046040)2.89803997
90establishment of integrated proviral latency (GO:0075713)2.88870755
91ATP-dependent chromatin remodeling (GO:0043044)2.87741438
92protein K6-linked ubiquitination (GO:0085020)2.86905623
93establishment of chromosome localization (GO:0051303)2.86516963
94attachment of spindle microtubules to kinetochore (GO:0008608)2.85538234
95histone H3-K9 methylation (GO:0051567)2.85505810
96regulation of mRNA stability (GO:0043488)2.85463596
97non-recombinational repair (GO:0000726)2.84740126
98double-strand break repair via nonhomologous end joining (GO:0006303)2.84740126
99L-alpha-amino acid transmembrane transport (GO:1902475)2.83712094
100histone exchange (GO:0043486)2.83393054
101DNA replication-independent nucleosome organization (GO:0034724)2.83278160
102DNA replication-independent nucleosome assembly (GO:0006336)2.83278160
103regulation of telomere maintenance via telomerase (GO:0032210)2.81909884
104formation of translation preinitiation complex (GO:0001731)2.81518725
105regulation of DNA endoreduplication (GO:0032875)2.81488897
106sister chromatid cohesion (GO:0007062)2.80102837
107regulation of centrosome duplication (GO:0010824)2.77628396
108cytoplasmic mRNA processing body assembly (GO:0033962)2.77154371
109alternative mRNA splicing, via spliceosome (GO:0000380)2.76639752
110DNA strand elongation (GO:0022616)2.75236066
111chromosome segregation (GO:0007059)2.74967650
112plasma lipoprotein particle assembly (GO:0034377)2.74819757
113regulation of mitotic metaphase/anaphase transition (GO:0030071)2.74815917
114DNA replication checkpoint (GO:0000076)2.74457366
115DNA topological change (GO:0006265)2.74228896
116regulation of gene silencing (GO:0060968)2.74169137
117regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.73754239
118chromatin remodeling at centromere (GO:0031055)2.73033406
119binding of sperm to zona pellucida (GO:0007339)2.72372974
120nucleobase biosynthetic process (GO:0046112)2.72201697
121nucleic acid transport (GO:0050657)2.72199360
122establishment of RNA localization (GO:0051236)2.72199360
123positive regulation of hormone metabolic process (GO:0032352)2.72028408
124RNA transport (GO:0050658)2.71781618
125DNA synthesis involved in DNA repair (GO:0000731)2.71684808
126spindle checkpoint (GO:0031577)2.71396910
127negative regulation of mitotic sister chromatid separation (GO:2000816)2.67927739
128negative regulation of sister chromatid segregation (GO:0033046)2.67927739
129negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.67927739
130negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.67927739
131negative regulation of mitotic sister chromatid segregation (GO:0033048)2.67927739
132mitotic spindle checkpoint (GO:0071174)2.67346161
133protein-DNA complex disassembly (GO:0032986)2.64871132
134nucleosome disassembly (GO:0006337)2.64871132
135regulation of mitotic sister chromatid segregation (GO:0033047)2.64331931

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.33744277
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.42016626
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.63784568
4* MYC_18555785_ChIP-Seq_MESCs_Mouse3.32794583
5MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.16842776
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.15069273
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.00308859
8AR_21909140_ChIP-Seq_LNCAP_Human2.82238332
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.66265474
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.54576143
11* E2F1_21310950_ChIP-Seq_MCF-7_Human2.47110066
12MYC_22102868_ChIP-Seq_BL_Human2.37541381
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.23600352
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.19223258
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.09701907
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.00924191
17E2F7_22180533_ChIP-Seq_HELA_Human10.5635400
18NELFA_20434984_ChIP-Seq_ESCs_Mouse1.97721268
19SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.94598654
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94532773
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.88047579
22MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85636832
23CIITA_25753668_ChIP-Seq_RAJI_Human1.80336493
24KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.78841195
25THAP11_20581084_ChIP-Seq_MESCs_Mouse1.76392768
26RBPJ_22232070_ChIP-Seq_NCS_Mouse1.73021084
27XRN2_22483619_ChIP-Seq_HELA_Human1.70435616
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.60253792
29KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.57940609
30KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.57940609
31KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.57940609
32SOX2_18555785_ChIP-Seq_MESCs_Mouse1.55301696
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.54734573
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54671895
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.52694214
36HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.50106112
37KDM5A_27292631_Chip-Seq_BREAST_Human1.49477537
38ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.49331160
39CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.43761578
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43496133
41CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.40053623
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37545520
43ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35073789
44CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32774196
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32522056
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31937685
47POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.31238873
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.30662295
49SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.30330930
50NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.29513983
51NANOG_21062744_ChIP-ChIP_HESCs_Human1.29050103
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26383277
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25341120
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.24071135
55TCF3_18692474_ChIP-Seq_MESCs_Mouse1.24026555
56STAT6_21828071_ChIP-Seq_BEAS2B_Human1.23656699
57KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22348075
58TTF2_22483619_ChIP-Seq_HELA_Human1.21498986
59* DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20740487
60TCF7_22412390_ChIP-Seq_EML_Mouse1.20357718
61TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19372349
62STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19314694
63TCF3_18692474_ChIP-Seq_MEFs_Mouse1.18315088
64TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.18175880
65DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.16635835
66PKCTHETA_26484144_Chip-Seq_BREAST_Human1.16480394
67CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16165662
68NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.14403762
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.14308313
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.13665729
71* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13638826
72* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11234160
73CHD1_26751641_Chip-Seq_LNCaP_Human1.10072255
74E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09362787
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07817188
76PADI4_21655091_ChIP-ChIP_MCF-7_Human1.07422528
77TFEB_21752829_ChIP-Seq_HELA_Human1.07375559
78FOXP3_21729870_ChIP-Seq_TREG_Human1.06452160
79SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05444763
80SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.02627059
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.02315811
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02163303
83ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.01896424
84CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.01835304
85ZFP281_27345836_Chip-Seq_ESCs_Mouse1.01101187
86EST1_17652178_ChIP-ChIP_JURKAT_Human1.00586758
87ZNF263_19887448_ChIP-Seq_K562_Human1.00566044
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00535100
89FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00399799
90VDR_21846776_ChIP-Seq_THP-1_Human0.99880313
91ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99861214
92HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97955282
93NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.97580305
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.97389664
95GABP_19822575_ChIP-Seq_HepG2_Human0.97084629
96* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96705419
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96170691
98* VDR_23849224_ChIP-Seq_CD4+_Human0.96113097
99NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.95957492
100KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95810856
101CREB1_15753290_ChIP-ChIP_HEK293T_Human0.95542932
102FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93601986
103NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.92993576
104E2F1_18555785_ChIP-Seq_MESCs_Mouse0.92571713
105KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.92498346
106ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.92130824
107DCP1A_22483619_ChIP-Seq_HELA_Human0.90997940
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.90259145
109POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90170642
110* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90136584
111TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.90079536
112SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.89018798
113* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88319055
114HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.87848541
115TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87480765
116ETS1_20019798_ChIP-Seq_JURKAT_Human0.86888950
117CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.86299567
118ELK1_19687146_ChIP-ChIP_HELA_Human0.85087324
119HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84853828
120NCOR1_26117541_ChIP-Seq_K562_Human0.84584902
121SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.83253546
122SOX17_20123909_ChIP-Seq_XEN_Mouse0.82650375
123SOX2_18692474_ChIP-Seq_MESCs_Mouse0.82442558
124KAP1_27257070_Chip-Seq_ESCs_Mouse0.81560995
125ELF1_17652178_ChIP-ChIP_JURKAT_Human0.80939679
126GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80345698
127SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.80257058
128KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.79425721

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.54755764
2MP0008057_abnormal_DNA_replication3.38597916
3MP0003111_abnormal_nucleus_morphology3.37794933
4MP0003693_abnormal_embryo_hatching3.12692205
5MP0003077_abnormal_cell_cycle3.03065377
6MP0004957_abnormal_blastocyst_morpholog2.94024564
7MP0010352_gastrointestinal_tract_polyps2.62146714
8MP0003718_maternal_effect2.61413209
9MP0000566_synostosis2.45491480
10MP0003705_abnormal_hypodermis_morpholog2.40344246
11MP0003123_paternal_imprinting2.34901148
12MP0001730_embryonic_growth_arrest2.33293482
13MP0010030_abnormal_orbit_morphology2.24575425
14MP0008877_abnormal_DNA_methylation2.23836157
15MP0008007_abnormal_cellular_replicative2.23381670
16MP0008260_abnormal_autophagy2.22550069
17MP0003890_abnormal_embryonic-extraembry2.20351035
18MP0005076_abnormal_cell_differentiation2.19841308
19MP0000350_abnormal_cell_proliferation2.09258139
20MP0000537_abnormal_urethra_morphology2.07867082
21MP0005380_embryogenesis_phenotype2.05516907
22MP0001672_abnormal_embryogenesis/_devel2.05516907
23MP0004197_abnormal_fetal_growth/weight/2.03566162
24MP0003121_genomic_imprinting2.03194128
25MP0002084_abnormal_developmental_patter1.99978112
26MP0008058_abnormal_DNA_repair1.95160010
27MP0010307_abnormal_tumor_latency1.95116334
28MP0003984_embryonic_growth_retardation1.88304321
29MP0009053_abnormal_anal_canal1.87493649
30MP0002088_abnormal_embryonic_growth/wei1.87237742
31MP0002085_abnormal_embryonic_tissue1.86209218
32MP0001697_abnormal_embryo_size1.79707859
33MP0006292_abnormal_olfactory_placode1.79339156
34MP0003567_abnormal_fetal_cardiomyocyte1.74041469
35MP0002086_abnormal_extraembryonic_tissu1.71922415
36MP0001293_anophthalmia1.70499585
37MP0002653_abnormal_ependyma_morphology1.69438204
38MP0008932_abnormal_embryonic_tissue1.64785205
39MP0004264_abnormal_extraembryonic_tissu1.63583673
40MP0005408_hypopigmentation1.60403032
41MP0005451_abnormal_body_composition1.58028290
42MP0003937_abnormal_limbs/digits/tail_de1.57372985
43MP0002089_abnormal_postnatal_growth/wei1.53077872
44MP0000569_abnormal_digit_pigmentation1.52026883
45MP0005058_abnormal_lysosome_morphology1.51865946
46MP0003172_abnormal_lysosome_physiology1.51193765
47MP0009672_abnormal_birth_weight1.50163373
48MP0002080_prenatal_lethality1.49832989
49MP0002254_reproductive_system_inflammat1.46173722
50MP0003119_abnormal_digestive_system1.41655817
51MP0003115_abnormal_respiratory_system1.39973250
52MP0004808_abnormal_hematopoietic_stem1.39922438
53MP0002396_abnormal_hematopoietic_system1.35130647
54MP0009703_decreased_birth_body1.34706722
55MP0000428_abnormal_craniofacial_morphol1.31945043
56MP0002092_abnormal_eye_morphology1.30796355
57MP0002697_abnormal_eye_size1.28529737
58MP0004381_abnormal_hair_follicle1.26017247
59MP0001849_ear_inflammation1.25460485
60MP0003935_abnormal_craniofacial_develop1.25161533
61MP0002210_abnormal_sex_determination1.24247326
62MP0003453_abnormal_keratinocyte_physiol1.24137760
63MP0001929_abnormal_gametogenesis1.22609587
64MP0000733_abnormal_muscle_development1.21928511
65MP0001915_intracranial_hemorrhage1.16479177
66MP0000432_abnormal_head_morphology1.15586416
67MP0000678_abnormal_parathyroid_gland1.14931723
68MP0003786_premature_aging1.14404338
69MP0003699_abnormal_female_reproductive1.14312234
70MP0005171_absent_coat_pigmentation1.13308788
71MP0002111_abnormal_tail_morphology1.12051353
72MP0001145_abnormal_male_reproductive1.10913622
73MP0005257_abnormal_intraocular_pressure1.05865109
74MP0009278_abnormal_bone_marrow1.05844967
75MP0005395_other_phenotype1.04333227
76MP0002932_abnormal_joint_morphology1.04180510
77MP0001324_abnormal_eye_pigmentation1.03261025
78MP0001286_abnormal_eye_development1.03052766
79MP0003385_abnormal_body_wall1.02306870
80MP0010234_abnormal_vibrissa_follicle1.00215573
81MP0002925_abnormal_cardiovascular_devel0.99881270
82MP0004233_abnormal_muscle_weight0.98376941
83MP0000313_abnormal_cell_death0.98116284
84MP0000653_abnormal_sex_gland0.97263430
85MP0002796_impaired_skin_barrier0.95622018
86MP0002098_abnormal_vibrissa_morphology0.95463279
87MP0005621_abnormal_cell_physiology0.94706333
88MP0005384_cellular_phenotype0.94067711
89MP0005499_abnormal_olfactory_system0.92778551
90MP0005394_taste/olfaction_phenotype0.92778551
91MP0003861_abnormal_nervous_system0.91066481
92MP0000490_abnormal_crypts_of0.91018629
93MP0003943_abnormal_hepatobiliary_system0.88941023
94MP0004858_abnormal_nervous_system0.88563297
95MP0000383_abnormal_hair_follicle0.88358959
96MP0010678_abnormal_skin_adnexa0.87863245
97MP0005187_abnormal_penis_morphology0.87688850
98MP0002019_abnormal_tumor_incidence0.86525555
99MP0000358_abnormal_cell_content/0.86445219
100MP0002161_abnormal_fertility/fecundity0.86420335
101MP0005023_abnormal_wound_healing0.86043877
102MP0003755_abnormal_palate_morphology0.85971286
103MP0004185_abnormal_adipocyte_glucose0.85651383
104MP0003136_yellow_coat_color0.85372787
105MP0003942_abnormal_urinary_system0.84978253
106MP0002282_abnormal_trachea_morphology0.84341740
107MP0006035_abnormal_mitochondrial_morpho0.83969997
108MP0002938_white_spotting0.83795167
109MP0003698_abnormal_male_reproductive0.83205455
110MP0008789_abnormal_olfactory_epithelium0.80329406
111MP0005501_abnormal_skin_physiology0.80216936
112MP0002114_abnormal_axial_skeleton0.80108208
113MP0003941_abnormal_skin_development0.78926689
114MP0003122_maternal_imprinting0.78696059
115MP0002249_abnormal_larynx_morphology0.78222746
116MP0002116_abnormal_craniofacial_bone0.77656713
117MP0008770_decreased_survivor_rate0.77284620
118MP0005377_hearing/vestibular/ear_phenot0.76495361
119MP0003878_abnormal_ear_physiology0.76495361
120MP0002877_abnormal_melanocyte_morpholog0.76052996
121MP0000266_abnormal_heart_morphology0.75896506
122MP0003787_abnormal_imprinting0.74890005
123MP0001346_abnormal_lacrimal_gland0.74733782
124MP0003566_abnormal_cell_adhesion0.74546794
125MP0003315_abnormal_perineum_morphology0.74511309
126MP0005248_abnormal_Harderian_gland0.73943625
127MP0005410_abnormal_fertilization0.73756717
128MP0003283_abnormal_digestive_organ0.73458849
129MP0000703_abnormal_thymus_morphology0.73286223
130MP0004133_heterotaxia0.72288177
131MP0009333_abnormal_splenocyte_physiolog0.71799528
132MP0000377_abnormal_hair_follicle0.71691457
133MP0002233_abnormal_nose_morphology0.71146846
134MP0006054_spinal_hemorrhage0.70420821
135MP0005623_abnormal_meninges_morphology0.70280316
136MP0005397_hematopoietic_system_phenotyp0.68650647

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.76272422
2Short 4th metacarpal (HP:0010044)3.76272422
3Medulloblastoma (HP:0002885)3.17317488
4Progressive external ophthalmoplegia (HP:0000590)3.14540554
5Ependymoma (HP:0002888)3.11986693
6Selective tooth agenesis (HP:0001592)3.07695447
7Increased nuchal translucency (HP:0010880)2.99423990
8Cholecystitis (HP:0001082)2.88415307
9Abnormal gallbladder physiology (HP:0012438)2.88415307
10Abnormality of cochlea (HP:0000375)2.87012926
11Chromsome breakage (HP:0040012)2.84878306
12Colon cancer (HP:0003003)2.83194426
13Abnormality of the 4th metacarpal (HP:0010012)2.82912539
14Volvulus (HP:0002580)2.75850308
15Ectopic kidney (HP:0000086)2.71916306
16Renal duplication (HP:0000075)2.71567651
17Rhabdomyosarcoma (HP:0002859)2.68771642
18Neoplasm of the oral cavity (HP:0100649)2.68676808
19Neoplasm of striated muscle (HP:0009728)2.62966561
20Chromosomal breakage induced by crosslinking agents (HP:0003221)2.61025212
21Abnormality of the fingertips (HP:0001211)2.59062295
22Deep venous thrombosis (HP:0002625)2.58318980
23Multiple enchondromatosis (HP:0005701)2.56236982
24Deviation of the thumb (HP:0009603)2.53837785
25Abnormality of the astrocytes (HP:0100707)2.51511153
26Astrocytoma (HP:0009592)2.51511153
27Renovascular hypertension (HP:0100817)2.51435802
28Abnormal number of incisors (HP:0011064)2.50619168
29Vaginal fistula (HP:0004320)2.49602685
30Hyperacusis (HP:0010780)2.48849490
31Proximal placement of thumb (HP:0009623)2.47704022
32Impulsivity (HP:0100710)2.46832315
33Skull defect (HP:0001362)2.42174517
34Microvesicular hepatic steatosis (HP:0001414)2.39730218
35Aplasia involving forearm bones (HP:0009822)2.38784076
36Absent forearm bone (HP:0003953)2.38784076
37Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.38777635
38Absent epiphyses (HP:0010577)2.38777635
39Flat acetabular roof (HP:0003180)2.36654221
40Horseshoe kidney (HP:0000085)2.34118192
41Heterotopia (HP:0002282)2.33502625
42Morphological abnormality of the inner ear (HP:0011390)2.30878566
43Intestinal fistula (HP:0100819)2.28932300
44Long eyelashes (HP:0000527)2.26710502
45Pseudobulbar signs (HP:0002200)2.23257667
46Abnormality of chromosome stability (HP:0003220)2.22873806
47Glioma (HP:0009733)2.21647977
48Abnormality of the salivary glands (HP:0010286)2.19995358
49Leiomyosarcoma (HP:0100243)2.18236460
50Uterine leiomyosarcoma (HP:0002891)2.18236460
51Supernumerary ribs (HP:0005815)2.17976877
52Trigonocephaly (HP:0000243)2.17965035
53Abnormality of the labia minora (HP:0012880)2.17598901
54Hypoplasia of the capital femoral epiphysis (HP:0003090)2.16757825
55Skin tags (HP:0010609)2.15831427
56Facial hemangioma (HP:0000329)2.15343811
57Meckel diverticulum (HP:0002245)2.12399823
58Prominent nose (HP:0000448)2.10975812
59Peripheral hypomyelination (HP:0007182)2.08529773
60Embryonal neoplasm (HP:0002898)2.07108415
61Choanal atresia (HP:0000453)2.04791634
62Broad thumb (HP:0011304)2.03708055
63Hypercholesterolemia (HP:0003124)2.02884513
64Elfin facies (HP:0004428)2.02841310
65Aplasia/Hypoplasia of the sternum (HP:0006714)2.02687065
66Aplasia/Hypoplasia of the uvula (HP:0010293)2.02314728
67Shallow orbits (HP:0000586)2.00545265
68Agnosia (HP:0010524)2.00254924
69Abnormality of the carotid arteries (HP:0005344)1.99710027
70Sandal gap (HP:0001852)1.99498142
71Duodenal stenosis (HP:0100867)1.99455015
72Small intestinal stenosis (HP:0012848)1.99455015
73Hypoplastic labia majora (HP:0000059)1.98929621
74Cortical dysplasia (HP:0002539)1.98862510
75Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.98788615
76Renal cell carcinoma (HP:0005584)1.97949843
77Abnormality of the ileum (HP:0001549)1.97915998
78Basal cell carcinoma (HP:0002671)1.97379025
79High pitched voice (HP:0001620)1.97365761
80Birth length less than 3rd percentile (HP:0003561)1.97337712
81Patellar aplasia (HP:0006443)1.96700729
82Supernumerary bones of the axial skeleton (HP:0009144)1.96085640
83Broad palm (HP:0001169)1.95898359
84Broad alveolar ridges (HP:0000187)1.94062124
85Small epiphyses (HP:0010585)1.94005017
86Rectal prolapse (HP:0002035)1.93793510
87Duplication of thumb phalanx (HP:0009942)1.93303335
88Abnormality of the diencephalon (HP:0010662)1.92704964
89Missing ribs (HP:0000921)1.91545409
90Esophageal atresia (HP:0002032)1.91494781
91Anal stenosis (HP:0002025)1.91436518
92Abnormality of the distal phalanx of the thumb (HP:0009617)1.91233023
93Gastrointestinal carcinoma (HP:0002672)1.90481592
94Malignant gastrointestinal tract tumors (HP:0006749)1.90481592
95Preauricular skin tag (HP:0000384)1.89420389
96Atresia of the external auditory canal (HP:0000413)1.89393192
97Hepatoblastoma (HP:0002884)1.89317444
98Rectal fistula (HP:0100590)1.89101286
99Rectovaginal fistula (HP:0000143)1.89101286
100Rib fusion (HP:0000902)1.88934056
101Truncal obesity (HP:0001956)1.87564370
102Nephroblastoma (Wilms tumor) (HP:0002667)1.87189719
103Irregular epiphyses (HP:0010582)1.87127957
104Overriding aorta (HP:0002623)1.86230648
105Hypophosphatemic rickets (HP:0004912)1.85556804
106Metaphyseal cupping (HP:0003021)1.85362215
107Limited elbow extension (HP:0001377)1.83804155
108Obsessive-compulsive behavior (HP:0000722)1.83295264
109Aplasia/Hypoplasia of the patella (HP:0006498)1.82454315
110Abnormality of the lower motor neuron (HP:0002366)1.81414426
111Short phalanx of the thumb (HP:0009660)1.80576928
112Abnormal lung lobation (HP:0002101)1.80568294
113Abnormality of the duodenum (HP:0002246)1.80284363
114Broad distal phalanx of finger (HP:0009836)1.80115738
115Overlapping toe (HP:0001845)1.79894508
116Abnormal tarsal ossification (HP:0008369)1.79710033
117Myelodysplasia (HP:0002863)1.79550239
118Broad phalanges of the hand (HP:0009768)1.79316810
119Oligodactyly (HP:0012165)1.79226298
120Cafe-au-lait spot (HP:0000957)1.79143604
121Capillary hemangiomas (HP:0005306)1.78251681
122Short humerus (HP:0005792)1.78166474
123Biliary tract neoplasm (HP:0100574)1.77925469
124Disproportionate tall stature (HP:0001519)1.76645766
125High anterior hairline (HP:0009890)1.76421884
126Abnormality of the labia majora (HP:0012881)1.76287170
127Progressive muscle weakness (HP:0003323)1.76170614
128Premature ovarian failure (HP:0008209)1.75112208
129Supernumerary spleens (HP:0009799)1.74446717
130Urethral obstruction (HP:0000796)1.73847710
131Sloping forehead (HP:0000340)1.73843534
132Hypopigmentation of the fundus (HP:0007894)1.72834818
133Embryonal renal neoplasm (HP:0011794)1.72375606
134Segmental peripheral demyelination/remyelination (HP:0003481)1.72322271
135Absent radius (HP:0003974)1.72033758
136Osteomalacia (HP:0002749)1.70772752
137Dysphonia (HP:0001618)1.70017960
138Deep philtrum (HP:0002002)1.69767081
139Facial cleft (HP:0002006)1.69387712
140Low anterior hairline (HP:0000294)1.69128563
141Abdominal situs inversus (HP:0003363)1.67862452
142Abnormality of abdominal situs (HP:0011620)1.67862452
143Bowel diverticulosis (HP:0005222)1.67779236
144Aplasia/hypoplasia of the humerus (HP:0006507)1.67376967
145Bifid scrotum (HP:0000048)1.67011226
146Deep palmar crease (HP:0006191)1.66719685
147Abnormality of glycolysis (HP:0004366)1.66325303
148Short 5th finger (HP:0009237)1.65634749
149Delayed epiphyseal ossification (HP:0002663)1.65456113
150Abnormality of the preputium (HP:0100587)1.65320086
151Subacute progressive viral hepatitis (HP:0006572)1.65297015
152Narrow palate (HP:0000189)1.65002257
153Premature skin wrinkling (HP:0100678)1.64210620

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.57657557
2CDC74.40154391
3LATS13.26207788
4SMG13.15320193
5NEK22.94112311
6EEF2K2.81121202
7TTK2.47296414
8FGFR42.43982470
9MAP3K102.35078947
10BRD42.33997492
11PBK2.19580455
12WEE12.17628402
13PKN21.94560185
14MKNK11.91613941
15PASK1.88910828
16SRPK11.86990138
17BRSK11.85740985
18RPS6KB21.73074871
19TRIB31.73068052
20CDK41.68452858
21ATR1.66554203
22STK31.61847959
23MAP3K131.60126437
24MKNK21.60067185
25CHEK11.56603081
26CDK71.56448660
27STK101.53118930
28CHEK21.51378778
29BUB11.47706542
30CDK61.46810949
31ICK1.46461690
32MTOR1.45481806
33PLK11.43450657
34EPHA21.37531936
35AURKB1.34964841
36TSSK61.34573313
37IRAK31.32197096
38MAP3K91.25576236
39ATM1.24771502
40MAP3K81.24222746
41PTK61.22287297
42TTN1.21667854
43KSR21.21125432
44CAMK1D1.19226482
45NEK11.15773941
46FGFR11.14365032
47ALK1.14262439
48NME11.13129050
49PAK41.13031372
50FGR1.12567195
51LATS21.11702314
52TGFBR11.11418133
53PNCK1.11117149
54PLK31.08760214
55MELK1.07474710
56CAMK1G1.06964459
57TAOK21.04990771
58CDK21.04162307
59TAOK11.00862334
60STK38L0.99984443
61RPS6KA40.99955173
62PLK40.95910067
63MATK0.94884530
64DYRK30.94115203
65PAK20.92937897
66STK40.92709896
67NME20.92289150
68PDGFRA0.90492434
69CDK90.88007329
70CDK10.83113444
71BRSK20.82286917
72RIPK10.82260445
73PRKD30.81129341
74PDK30.79875704
75PDK40.79875704
76SIK10.79340152
77SCYL20.76612919
78MAP3K60.73295381
79TYRO30.71379635
80ACVR1B0.68860505
81RAF10.66748735
82BRAF0.65718525
83PRKDC0.65099732
84FGFR20.65091784
85VRK20.64270212
86CSNK1E0.63465156
87FLT30.62608972
88AKT20.62504448
89CSNK1D0.61570288
90PDGFRB0.58647589
91TLK10.58156766
92BMX0.58060707
93MET0.56777451
94ERBB20.55619887
95MAP2K30.55313904
96MAPK140.54612780
97WNK10.54200764
98AURKA0.53016093
99PIM10.52569898
100ZAK0.52449836
101MARK30.51013003
102MAP3K10.49170041
103ERN10.46871939
104GSK3B0.45608468
105STK240.45549891
106MAP3K140.45244176
107CSNK2A20.43905484
108EIF2AK10.43843567
109CSNK1A1L0.43826135
110ARAF0.43124559
111MAPK10.42942209
112AKT10.41359962
113RPS6KA10.40099353
114PDK20.39542042
115NLK0.39080005
116CDK80.38622098
117PTK20.38311937
118LRRK20.37582894
119NEK60.37434726
120CDC42BPA0.36114419
121NTRK10.35654351
122FGFR30.35229828
123MARK20.35141841
124CHUK0.34610269
125CSNK1G10.32723249
126DYRK1B0.32174658
127MAPK100.32048220
128SIK30.31723917
129SIK20.30860945
130VRK10.30586266
131GRK60.28694202
132ERBB40.28418677
133MAP4K10.28396967
134DDR20.28141115

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.63397463
2Mismatch repair_Homo sapiens_hsa034303.27815191
3One carbon pool by folate_Homo sapiens_hsa006703.16717216
4RNA transport_Homo sapiens_hsa030133.14758473
5Spliceosome_Homo sapiens_hsa030402.91129466
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.88055890
7Cell cycle_Homo sapiens_hsa041102.85424376
8mRNA surveillance pathway_Homo sapiens_hsa030152.59561228
9Lysine degradation_Homo sapiens_hsa003102.28978797
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.26470752
11Base excision repair_Homo sapiens_hsa034102.16786805
12Fanconi anemia pathway_Homo sapiens_hsa034602.13682995
13Homologous recombination_Homo sapiens_hsa034402.08123995
14Steroid biosynthesis_Homo sapiens_hsa001002.01434694
15Nucleotide excision repair_Homo sapiens_hsa034201.96797090
16RNA degradation_Homo sapiens_hsa030181.91523231
17Basal cell carcinoma_Homo sapiens_hsa052171.83985862
18Non-homologous end-joining_Homo sapiens_hsa034501.79305652
19Systemic lupus erythematosus_Homo sapiens_hsa053221.76085412
20Selenocompound metabolism_Homo sapiens_hsa004501.62575676
21MicroRNAs in cancer_Homo sapiens_hsa052061.58095401
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.56255700
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.45532476
24Other glycan degradation_Homo sapiens_hsa005111.42114435
25Small cell lung cancer_Homo sapiens_hsa052221.40404202
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.38161823
27Hippo signaling pathway_Homo sapiens_hsa043901.35676353
28Adherens junction_Homo sapiens_hsa045201.32109641
29p53 signaling pathway_Homo sapiens_hsa041151.31970364
30Viral carcinogenesis_Homo sapiens_hsa052031.30536440
31Basal transcription factors_Homo sapiens_hsa030221.30328280
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.28233432
33Hedgehog signaling pathway_Homo sapiens_hsa043401.26570625
34TGF-beta signaling pathway_Homo sapiens_hsa043501.19547071
35HTLV-I infection_Homo sapiens_hsa051661.17987970
36Notch signaling pathway_Homo sapiens_hsa043301.15830160
37Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.11229618
38Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09552340
39Biosynthesis of amino acids_Homo sapiens_hsa012301.07900849
40Chronic myeloid leukemia_Homo sapiens_hsa052201.06974893
41mTOR signaling pathway_Homo sapiens_hsa041501.05144766
42Oocyte meiosis_Homo sapiens_hsa041141.04936886
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.03954528
44Fructose and mannose metabolism_Homo sapiens_hsa000511.01312558
45Central carbon metabolism in cancer_Homo sapiens_hsa052301.00914872
46Herpes simplex infection_Homo sapiens_hsa051681.00449753
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.98402939
48Cysteine and methionine metabolism_Homo sapiens_hsa002700.96778043
49Pyrimidine metabolism_Homo sapiens_hsa002400.96735622
50Colorectal cancer_Homo sapiens_hsa052100.92399578
51RNA polymerase_Homo sapiens_hsa030200.90108188
52Thyroid cancer_Homo sapiens_hsa052160.87890302
53Thyroid hormone signaling pathway_Homo sapiens_hsa049190.87588202
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.86686837
55Proteoglycans in cancer_Homo sapiens_hsa052050.85812378
56N-Glycan biosynthesis_Homo sapiens_hsa005100.83208346
57Prostate cancer_Homo sapiens_hsa052150.79503724
58Antigen processing and presentation_Homo sapiens_hsa046120.77250540
59Wnt signaling pathway_Homo sapiens_hsa043100.76713455
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75716555
61Epstein-Barr virus infection_Homo sapiens_hsa051690.75119225
62Bladder cancer_Homo sapiens_hsa052190.72254731
63Non-small cell lung cancer_Homo sapiens_hsa052230.71390277
64Endometrial cancer_Homo sapiens_hsa052130.70182498
65Cyanoamino acid metabolism_Homo sapiens_hsa004600.70050345
66Proteasome_Homo sapiens_hsa030500.69729443
67Pathways in cancer_Homo sapiens_hsa052000.69462280
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68741692
69Vitamin B6 metabolism_Homo sapiens_hsa007500.68285319
70Vitamin digestion and absorption_Homo sapiens_hsa049770.67626572
71Galactose metabolism_Homo sapiens_hsa000520.67227998
72Complement and coagulation cascades_Homo sapiens_hsa046100.66863894
73Tight junction_Homo sapiens_hsa045300.63685712
74Pyruvate metabolism_Homo sapiens_hsa006200.63114821
75Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61700251
76Viral myocarditis_Homo sapiens_hsa054160.61615055
77Pancreatic cancer_Homo sapiens_hsa052120.60622353
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60411886
79Renal cell carcinoma_Homo sapiens_hsa052110.58510469
80Alcoholism_Homo sapiens_hsa050340.57285137
81Lysosome_Homo sapiens_hsa041420.57039444
82Glucagon signaling pathway_Homo sapiens_hsa049220.56276313
83AMPK signaling pathway_Homo sapiens_hsa041520.53768231
84Fatty acid biosynthesis_Homo sapiens_hsa000610.53196699
85Dorso-ventral axis formation_Homo sapiens_hsa043200.50905504
86Focal adhesion_Homo sapiens_hsa045100.50122819
87Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50010074
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48545649
89FoxO signaling pathway_Homo sapiens_hsa040680.48207885
90ECM-receptor interaction_Homo sapiens_hsa045120.45563843
91Hepatitis B_Homo sapiens_hsa051610.45345334
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.44676316
93Insulin resistance_Homo sapiens_hsa049310.43835852
94Carbon metabolism_Homo sapiens_hsa012000.42845966
95HIF-1 signaling pathway_Homo sapiens_hsa040660.41323517
96Acute myeloid leukemia_Homo sapiens_hsa052210.41011055
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.40431032
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40044445
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38672183
100Pentose phosphate pathway_Homo sapiens_hsa000300.36996999
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.36502011
102Ribosome_Homo sapiens_hsa030100.35516633
103Purine metabolism_Homo sapiens_hsa002300.35245366
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.35080462
105Legionellosis_Homo sapiens_hsa051340.34217935
106Melanoma_Homo sapiens_hsa052180.33824351
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33798136
108Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33306631
109Sulfur relay system_Homo sapiens_hsa041220.31380923
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.31024207
111Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.30690875
112ErbB signaling pathway_Homo sapiens_hsa040120.30611895
113Prion diseases_Homo sapiens_hsa050200.30531621
114Nitrogen metabolism_Homo sapiens_hsa009100.29907976
115PI3K-Akt signaling pathway_Homo sapiens_hsa041510.29143575
116Insulin signaling pathway_Homo sapiens_hsa049100.28051909
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.26314465
118Glioma_Homo sapiens_hsa052140.25049753
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.24236171
120Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.24155423
121Apoptosis_Homo sapiens_hsa042100.23968370
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.22881925
123Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.22876250
124Influenza A_Homo sapiens_hsa051640.22309213
125Inositol phosphate metabolism_Homo sapiens_hsa005620.21806644
126Toxoplasmosis_Homo sapiens_hsa051450.21568732
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.21555244

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