TTLL9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.95604143
2cell-cell recognition (GO:0009988)9.39555797
3cilium movement (GO:0003341)9.34248509
4binding of sperm to zona pellucida (GO:0007339)9.28705316
5plasma membrane fusion (GO:0045026)9.26716713
6reproduction (GO:0000003)8.84920772
7spermatid development (GO:0007286)8.74384450
8regulation of cilium movement (GO:0003352)7.85126897
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.44807997
10piRNA metabolic process (GO:0034587)7.36212723
11single fertilization (GO:0007338)7.31998979
12male meiosis (GO:0007140)6.60897244
13microtubule depolymerization (GO:0007019)6.49498371
14synaptonemal complex organization (GO:0070193)6.13608906
15ventricular system development (GO:0021591)6.05302388
16sperm capacitation (GO:0048240)6.04668614
17spermatogenesis (GO:0007283)6.02170712
18microtubule bundle formation (GO:0001578)6.01211362
19male gamete generation (GO:0048232)6.00262833
20fertilization (GO:0009566)5.98245188
21synaptonemal complex assembly (GO:0007130)5.75264257
22negative regulation of inclusion body assembly (GO:0090084)5.54069074
23gamete generation (GO:0007276)5.52131187
24organic cation transport (GO:0015695)5.46532039
25primary alcohol catabolic process (GO:0034310)5.11774905
26vitamin transmembrane transport (GO:0035461)5.07000829
27DNA methylation involved in gamete generation (GO:0043046)5.00674935
28axoneme assembly (GO:0035082)4.83635974
29calcium ion-dependent exocytosis (GO:0017156)4.82922525
30germ cell development (GO:0007281)4.81541626
31cellular process involved in reproduction in multicellular organism (GO:0022412)4.75298430
32spermatid nucleus differentiation (GO:0007289)4.70973541
33male meiosis I (GO:0007141)4.63959419
34regulation of inclusion body assembly (GO:0090083)4.60646603
35cell recognition (GO:0008037)4.52568036
36response to xenobiotic stimulus (GO:0009410)4.51566643
37GTP biosynthetic process (GO:0006183)4.51160446
38regulation of microtubule-based movement (GO:0060632)4.42689558
39ethanol metabolic process (GO:0006067)4.42444356
40nucleoside diphosphate phosphorylation (GO:0006165)4.36408112
41chromosome condensation (GO:0030261)4.33539994
42multicellular organismal reproductive process (GO:0048609)4.33395288
43chromosome organization involved in meiosis (GO:0070192)4.33104693
44diterpenoid biosynthetic process (GO:0016102)4.27481188
45DNA packaging (GO:0006323)4.19463599
46cell projection assembly (GO:0030031)4.11427681
47meiotic nuclear division (GO:0007126)4.08157258
48pyrimidine-containing compound transmembrane transport (GO:0072531)4.00782301
49UTP biosynthetic process (GO:0006228)4.00676739
50centriole assembly (GO:0098534)4.00166757
51negative regulation of T cell differentiation in thymus (GO:0033085)3.96611109
52one-carbon compound transport (GO:0019755)3.96447872
53microtubule severing (GO:0051013)3.89830816
54glycerol ether metabolic process (GO:0006662)3.86337754
55left/right pattern formation (GO:0060972)3.86009586
56meiotic cell cycle (GO:0051321)3.72503847
57meiosis I (GO:0007127)3.62897651
58lung epithelium development (GO:0060428)3.60969770
59cilium organization (GO:0044782)3.59899534
60ether metabolic process (GO:0018904)3.57642185
61single strand break repair (GO:0000012)3.57309795
62lateral ventricle development (GO:0021670)3.56068357
63UTP metabolic process (GO:0046051)3.54928731
64seminiferous tubule development (GO:0072520)3.54760137
65sequestering of actin monomers (GO:0042989)3.53853067
66determination of left/right symmetry (GO:0007368)3.52999772
67protein K11-linked deubiquitination (GO:0035871)3.47957457
68left/right axis specification (GO:0070986)3.46281076
69cilium assembly (GO:0042384)3.45080236
70protein polyglutamylation (GO:0018095)3.42861282
71regulation of interleukin-5 production (GO:0032674)3.40163152
72protein localization to cilium (GO:0061512)3.40033090
73exogenous drug catabolic process (GO:0042738)3.39188756
74multicellular organismal development (GO:0007275)3.37286213
75determination of bilateral symmetry (GO:0009855)3.35977184
76microtubule polymerization or depolymerization (GO:0031109)3.34606938
77smoothened signaling pathway (GO:0007224)3.33592061
78intraciliary transport (GO:0042073)3.31339999
79nonmotile primary cilium assembly (GO:0035058)3.30300913
80glomerular epithelial cell development (GO:0072310)3.28751805
81specification of symmetry (GO:0009799)3.26297807
82retinoic acid metabolic process (GO:0042573)3.25513182
83terpenoid biosynthetic process (GO:0016114)3.24897666
84cytoplasmic microtubule organization (GO:0031122)3.21347436
85cellular component assembly involved in morphogenesis (GO:0010927)3.20007697
86guanosine-containing compound biosynthetic process (GO:1901070)3.14821693
87CTP biosynthetic process (GO:0006241)3.14536163
88CTP metabolic process (GO:0046036)3.14536163
89centriole replication (GO:0007099)3.14113746
90ethanol oxidation (GO:0006069)3.12633042
91cilium morphogenesis (GO:0060271)3.11630008
92photoreceptor cell maintenance (GO:0045494)3.08242682
93negative regulation of immunoglobulin mediated immune response (GO:0002890)3.07708215
94negative regulation of B cell mediated immunity (GO:0002713)3.07708215
95tolerance induction (GO:0002507)3.05912602
96microtubule-based movement (GO:0007018)3.03672784
97pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.01994648
98regulation of germinal center formation (GO:0002634)2.99077015
99regulation of interleukin-13 production (GO:0032656)2.98409304
100regulation of spindle checkpoint (GO:0090231)2.96671267
101retinal rod cell development (GO:0046548)2.93948634
102negative regulation of humoral immune response (GO:0002921)2.93673382
103establishment of tissue polarity (GO:0007164)2.93632433
104establishment of planar polarity (GO:0001736)2.93632433
105synapsis (GO:0007129)2.92283893
106chaperone-mediated protein complex assembly (GO:0051131)2.91948769
107pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.86623064
108aldehyde catabolic process (GO:0046185)2.85702222
109retinal cone cell development (GO:0046549)2.82640787
110meiotic cell cycle process (GO:1903046)2.81553423
111monoubiquitinated protein deubiquitination (GO:0035520)2.75698933
112cornea development in camera-type eye (GO:0061303)2.75236748
113drug catabolic process (GO:0042737)2.74893336
114response to pheromone (GO:0019236)2.74261762
115establishment of apical/basal cell polarity (GO:0035089)2.73589582
116establishment of monopolar cell polarity (GO:0061162)2.73589490
117establishment or maintenance of monopolar cell polarity (GO:0061339)2.73589490
118organelle assembly (GO:0070925)2.70026905
119regulation of centriole replication (GO:0046599)2.69553760
120microtubule-based process (GO:0007017)2.68053678
121polyamine biosynthetic process (GO:0006596)2.67116212
122sexual reproduction (GO:0019953)2.66158247
123nucleotide phosphorylation (GO:0046939)2.66018153
124pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.62994888
125nucleus organization (GO:0006997)2.61942044
126phosphatidylethanolamine biosynthetic process (GO:0006646)2.60935349
127pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.59440412
128phosphatidylcholine biosynthetic process (GO:0006656)2.57642435
129glutathione derivative biosynthetic process (GO:1901687)2.56056453
130glutathione derivative metabolic process (GO:1901685)2.56056453
131interferon-gamma secretion (GO:0072643)2.53750612
132protein localization to chromosome, centromeric region (GO:0071459)2.52126742
133genitalia morphogenesis (GO:0035112)2.50518671
134nucleoside diphosphate metabolic process (GO:0009132)2.49759762
135protein refolding (GO:0042026)2.49507545
136retinol metabolic process (GO:0042572)2.49215893
137spinal cord motor neuron differentiation (GO:0021522)2.47555539
138polyol catabolic process (GO:0046174)2.46284626
139phosphatidylethanolamine metabolic process (GO:0046337)2.44724241
140primary alcohol metabolic process (GO:0034308)2.43294157
141lateral sprouting from an epithelium (GO:0060601)2.41627283
142positive regulation of smoothened signaling pathway (GO:0045880)2.40261170
143RNA destabilization (GO:0050779)2.37554257
144carnitine metabolic process (GO:0009437)2.37412802
145O-glycan processing (GO:0016266)2.35834399
146hydrogen peroxide biosynthetic process (GO:0050665)2.35544790
147heart looping (GO:0001947)2.34308538
148regulation of collateral sprouting (GO:0048670)2.32767106
149intra-S DNA damage checkpoint (GO:0031573)2.27280489
150reactive oxygen species biosynthetic process (GO:1903409)2.23172771
151excretion (GO:0007588)2.20943851
152L-fucose metabolic process (GO:0042354)2.18855734
153L-fucose catabolic process (GO:0042355)2.18855734
154fucose catabolic process (GO:0019317)2.18855734
155epithelial cell differentiation involved in kidney development (GO:0035850)2.18218210
156phenol-containing compound catabolic process (GO:0019336)2.17622637
157fusion of sperm to egg plasma membrane (GO:0007342)12.3201146
158sperm motility (GO:0030317)11.8675633
159cell wall macromolecule catabolic process (GO:0016998)11.6664527
160cell wall macromolecule metabolic process (GO:0044036)11.6664527
161cilium or flagellum-dependent cell motility (GO:0001539)11.0907708
162acrosome reaction (GO:0007340)11.0368963
163axonemal dynein complex assembly (GO:0070286)10.9103869
164multicellular organism reproduction (GO:0032504)10.6171006
165acrosome assembly (GO:0001675)10.5095632
166sperm-egg recognition (GO:0035036)10.4597689
167motile cilium assembly (GO:0044458)10.1594619

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.52082953
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.62775117
3EZH2_22144423_ChIP-Seq_EOC_Human3.51865770
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.16644409
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.16144507
6DROSHA_22980978_ChIP-Seq_HELA_Human2.86643428
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.83260067
8PCGF2_27294783_Chip-Seq_ESCs_Mouse2.59857994
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.39087200
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.31988944
11FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.30254337
12VDR_22108803_ChIP-Seq_LS180_Human2.29167404
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.17571968
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.14858812
15PIAS1_25552417_ChIP-Seq_VCAP_Human2.10292569
16NFE2_27457419_Chip-Seq_LIVER_Mouse2.01579223
17KAP1_22055183_ChIP-Seq_ESCs_Mouse1.98956173
18SUZ12_27294783_Chip-Seq_NPCs_Mouse1.98482942
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.98362022
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.92623151
21PCGF2_27294783_Chip-Seq_NPCs_Mouse1.90290667
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.89088459
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83548014
24GATA1_26923725_Chip-Seq_HPCs_Mouse1.83350518
25STAT1_17558387_ChIP-Seq_HELA_Human1.82220388
26NR3C1_21868756_ChIP-Seq_MCF10A_Human1.77447224
27GBX2_23144817_ChIP-Seq_PC3_Human1.76924117
28KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.67956432
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.62483264
30* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.59206152
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59083197
32AHR_22903824_ChIP-Seq_MCF-7_Human1.57901643
33SMAD4_21799915_ChIP-Seq_A2780_Human1.56853388
34* TAL1_26923725_Chip-Seq_HPCs_Mouse1.56706476
35TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56127382
36KDM2B_26808549_Chip-Seq_REH_Human1.55941145
37TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.55354115
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.53382032
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.52917962
40* ELK4_26923725_Chip-Seq_MESODERM_Mouse1.50208175
41FUS_26573619_Chip-Seq_HEK293_Human1.49790667
42ARNT_22903824_ChIP-Seq_MCF-7_Human1.49721923
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.49373338
44MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.48110657
45GATA3_21867929_ChIP-Seq_CD8_Mouse1.47833825
46CRX_20693478_ChIP-Seq_RETINA_Mouse1.47041131
47SOX2_22085726_ChIP-Seq_NPCs_Mouse1.45588820
48NANOG_18555785_Chip-Seq_ESCs_Mouse1.45120667
49* STAT3_23295773_ChIP-Seq_U87_Human1.43678472
50BCAT_22108803_ChIP-Seq_LS180_Human1.42609365
51P53_22387025_ChIP-Seq_ESCs_Mouse1.41856849
52CBX2_27304074_Chip-Seq_ESCs_Mouse1.41401475
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40312185
54CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.40189936
55EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.39199525
56AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.39024813
57FOXM1_26456572_ChIP-Seq_MCF-7_Human1.38638531
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36855023
59* OCT4_18555785_Chip-Seq_ESCs_Mouse1.36561699
60RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.36207362
61WDR5_24793694_ChIP-Seq_LNCAP_Human1.36098720
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.35765674
63OCT4_21477851_ChIP-Seq_ESCs_Mouse1.35414448
64AR_21572438_ChIP-Seq_LNCaP_Human1.35263659
65FOXA1_25329375_ChIP-Seq_VCAP_Human1.34375333
66FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34375333
67P300_19829295_ChIP-Seq_ESCs_Human1.33212741
68P300_18555785_Chip-Seq_ESCs_Mouse1.32679537
69PHF8_20622853_ChIP-Seq_HELA_Human1.32033092
70GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.31197011
71ZNF274_21170338_ChIP-Seq_K562_Hela1.30531945
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.30033691
73EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.29613447
74ESR1_20079471_ChIP-ChIP_T-47D_Human1.29608157
75GATA3_21867929_ChIP-Seq_TH1_Mouse1.29343865
76STAT3_18555785_Chip-Seq_ESCs_Mouse1.28414181
77CMYC_18555785_Chip-Seq_ESCs_Mouse1.28401773
78TCF4_22108803_ChIP-Seq_LS180_Human1.28200663
79SMRT_27268052_Chip-Seq_Bcells_Human1.27434139
80SUZ12_18555785_Chip-Seq_ESCs_Mouse1.26605145
81EWS_26573619_Chip-Seq_HEK293_Human1.26212387
82TP53_18474530_ChIP-ChIP_U2OS_Human1.25669166
83KLF4_18555785_Chip-Seq_ESCs_Mouse1.25205070
84CBP_20019798_ChIP-Seq_JUKART_Human1.25173827
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25173827
86HNFA_21074721_ChIP-Seq_CACO-2_Human1.24145104
87CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23697780
88PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.22084301
89* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21548683
90CTBP2_25329375_ChIP-Seq_LNCAP_Human1.20707158
91AR_25329375_ChIP-Seq_VCAP_Human1.20654698
92* TCF4_23295773_ChIP-Seq_U87_Human1.20446604
93AR_20517297_ChIP-Seq_VCAP_Human1.19953942
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19839239
95SMAD4_21741376_ChIP-Seq_EPCs_Human1.19705697
96* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.19697082
97CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.19617991
98* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19512873
99SOX2_18555785_Chip-Seq_ESCs_Mouse1.18117485
100* PU1_27457419_Chip-Seq_LIVER_Mouse1.17953721
101RUNX2_22187159_ChIP-Seq_PCA_Human1.17682068
102* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.17489542
103AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.17155159
104PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16827110
105TP63_23658742_ChIP-Seq_EP156T_Human1.16696371
106RBPJ_21746931_ChIP-Seq_IB4_Human1.16550823
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16543772
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16543772
109FLI1_21867929_ChIP-Seq_TH2_Mouse1.15806679
110NANOG_19829295_ChIP-Seq_ESCs_Human1.15739766
111SOX2_19829295_ChIP-Seq_ESCs_Human1.15739766
112ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.15311760
113RNF2_27304074_Chip-Seq_NSC_Mouse1.14616717
114CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14440516
115STAT1_20625510_ChIP-Seq_HELA_Human1.14226705
116* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13388095
117FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.13338488
118CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13219212
119ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.13182124
120TDRD3_21172665_ChIP-Seq_MCF-7_Human1.13118687
121NMYC_18555785_Chip-Seq_ESCs_Mouse1.12894701
122NCOR_22424771_ChIP-Seq_293T_Human1.12648409
123* GF1_26923725_Chip-Seq_HPCs_Mouse1.12579961
124E2F1_18555785_Chip-Seq_ESCs_Mouse1.12408275
125SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.12302168
126EZH2_27294783_Chip-Seq_ESCs_Mouse1.12263533
127MYC_19829295_ChIP-Seq_ESCs_Human1.12112629
128LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.11975878
129BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11253306
130SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11191357
131CTCF_18555785_Chip-Seq_ESCs_Mouse1.11058024
132PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.11001894
133EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10993747
134CBX2_22325352_ChIP-Seq_293T-Rex_Human1.08197286
135REST_21632747_ChIP-Seq_MESCs_Mouse1.08196767
136NFYA_21822215_ChIP-Seq_K562_Human1.08031902
137SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.07371394
138P53_21459846_ChIP-Seq_SAOS-2_Human1.06935015
139FOXA1_25552417_ChIP-Seq_VCAP_Human1.06876444
140GATA6_21074721_ChIP-Seq_CACO-2_Human1.06511791
141* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.06387047
142IRF8_27001747_Chip-Seq_BMDM_Mouse1.05935570
143EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.05921416
144NFYB_21822215_ChIP-Seq_K562_Human1.05729959
145TAF15_26573619_Chip-Seq_HEK293_Human1.05641740
146LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05634356
147PRDM14_20953172_ChIP-Seq_ESCs_Human1.05441389
148* ZFX_18555785_Chip-Seq_ESCs_Mouse1.05392681
149CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04309022
150RAD21_21589869_ChIP-Seq_MESCs_Mouse1.03408680
151GATA3_21878914_ChIP-Seq_MCF-7_Human1.02981357
152MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02888198
153IRF8_21731497_ChIP-ChIP_J774_Mouse1.02751702
154TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02363437
155FOXA1_21572438_ChIP-Seq_LNCaP_Human1.02218138
156* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01767372
157IGF1R_20145208_ChIP-Seq_DFB_Human1.01642167
158OCT4_20526341_ChIP-Seq_ESCs_Human1.01406473
159KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01353055
160SMAD3_21741376_ChIP-Seq_HESCs_Human1.01192503
161* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01006947
162* SMAD1_18555785_Chip-Seq_ESCs_Mouse1.00310290
163GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.00249242
164BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.00026934
165SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99919918
166RUNX1_26923725_Chip-Seq_HPCs_Mouse0.99846348
167ER_23166858_ChIP-Seq_MCF-7_Human0.97836725
168PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97394159
169CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96494543
170ETV1_20927104_ChIP-Seq_GIST48_Human0.96084922
171LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.95323823
172SPI1_26923725_Chip-Seq_HPCs_Mouse0.93394059
173* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93062171
174TBL1_22424771_ChIP-Seq_293T_Human0.93016014

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.35382200
2MP0008875_abnormal_xenobiotic_pharmacok5.23630510
3MP0001929_abnormal_gametogenesis4.92586798
4MP0008877_abnormal_DNA_methylation4.16477017
5MP0002210_abnormal_sex_determination3.23536717
6MP0004133_heterotaxia3.18430492
7MP0004043_abnormal_pH_regulation3.18275606
8MP0002161_abnormal_fertility/fecundity2.86720733
9MP0002277_abnormal_respiratory_mucosa2.67940562
10MP0008057_abnormal_DNA_replication2.66078859
11MP0001145_abnormal_male_reproductive2.61996748
12MP0002653_abnormal_ependyma_morphology2.32327687
13MP0000653_abnormal_sex_gland2.27488998
14MP0005670_abnormal_white_adipose2.24835886
15MP0001485_abnormal_pinna_reflex2.19426302
16MP0008789_abnormal_olfactory_epithelium2.19257355
17MP0000383_abnormal_hair_follicle2.18697811
18MP0009780_abnormal_chondrocyte_physiolo2.18602388
19MP0002160_abnormal_reproductive_system2.00830610
20MP0005410_abnormal_fertilization14.1046436
21MP0001835_abnormal_antigen_presentation1.92196748
22MP0005083_abnormal_biliary_tract1.91698276
23MP0008058_abnormal_DNA_repair1.87221246
24MP0005551_abnormal_eye_electrophysiolog1.84379903
25MP0003195_calcinosis1.79809379
26MP0002102_abnormal_ear_morphology1.75030743
27MP0002638_abnormal_pupillary_reflex1.74782883
28MP0003880_abnormal_central_pattern1.74083436
29MP0001986_abnormal_taste_sensitivity1.66835144
30MP0002909_abnormal_adrenal_gland1.60144355
31MP0000566_synostosis1.58769042
32MP0010678_abnormal_skin_adnexa1.57781430
33MP0005623_abnormal_meninges_morphology1.48162160
34MP0004885_abnormal_endolymph1.44857819
35MP0010094_abnormal_chromosome_stability1.44475376
36MP0004019_abnormal_vitamin_homeostasis1.44086151
37MP0005394_taste/olfaction_phenotype1.36672114
38MP0005499_abnormal_olfactory_system1.36672114
39MP0001486_abnormal_startle_reflex1.36198201
40MP0002254_reproductive_system_inflammat1.34640285
41MP0005647_abnormal_sex_gland1.26276435
42MP0009745_abnormal_behavioral_response1.25911201
43MP0009785_altered_susceptibility_to1.25268732
44MP0001984_abnormal_olfaction1.24202292
45MP0008995_early_reproductive_senescence1.23159729
46MP0001502_abnormal_circadian_rhythm1.20344007
47MP0002734_abnormal_mechanical_nocicepti1.19847935
48MP0008872_abnormal_physiological_respon1.17505206
49MP0002168_other_aberrant_phenotype1.16475805
50MP0002148_abnormal_hypersensitivity_rea1.15839540
51MP0003646_muscle_fatigue1.15276440
52MP0003111_abnormal_nucleus_morphology1.15169754
53MP0005636_abnormal_mineral_homeostasis1.14941563
54MP0005365_abnormal_bile_salt1.14163177
55MP0000631_abnormal_neuroendocrine_gland1.08528181
56MP0009046_muscle_twitch1.05481894
57MP0002282_abnormal_trachea_morphology1.02917471
58MP0000685_abnormal_immune_system1.01974949
59MP0002572_abnormal_emotion/affect_behav1.01282741
60MP0002405_respiratory_system_inflammati1.00457298
61MP0003878_abnormal_ear_physiology1.00220709
62MP0005377_hearing/vestibular/ear_phenot1.00220709
63MP0003136_yellow_coat_color0.99864727
64MP0001324_abnormal_eye_pigmentation0.96836422
65MP0006072_abnormal_retinal_apoptosis0.96673665
66MP0002229_neurodegeneration0.96512458
67MP0005395_other_phenotype0.95596759
68MP0005389_reproductive_system_phenotype0.95287127
69MP0005085_abnormal_gallbladder_physiolo0.95115684
70MP0001970_abnormal_pain_threshold0.94330239
71MP0002419_abnormal_innate_immunity0.94177435
72MP0002876_abnormal_thyroid_physiology0.94093621
73MP0009697_abnormal_copulation0.93954207
74MP0006082_CNS_inflammation0.93932934
75MP0005645_abnormal_hypothalamus_physiol0.93482721
76MP0005025_abnormal_response_to0.92272628
77MP0002272_abnormal_nervous_system0.92172092
78MP0005220_abnormal_exocrine_pancreas0.90500898
79MP0002557_abnormal_social/conspecific_i0.90481317
80MP0003656_abnormal_erythrocyte_physiolo0.88674538
81MP0004215_abnormal_myocardial_fiber0.87509956
82MP0003787_abnormal_imprinting0.86634920
83MP0001944_abnormal_pancreas_morphology0.85486403
84MP0008007_abnormal_cellular_replicative0.85142487
85MP0005195_abnormal_posterior_eye0.85068352
86MP0002735_abnormal_chemical_nociception0.84958289
87MP0004142_abnormal_muscle_tone0.84675320
88MP0002736_abnormal_nociception_after0.83216659
89MP0000427_abnormal_hair_cycle0.81112517
90MP0001293_anophthalmia0.80863710
91MP0010307_abnormal_tumor_latency0.80792231
92MP0006276_abnormal_autonomic_nervous0.78628116
93MP0001270_distended_abdomen0.78564340
94MP0003718_maternal_effect0.77517623
95MP0002064_seizures0.76164746
96MP0005174_abnormal_tail_pigmentation0.75654335
97MP0005391_vision/eye_phenotype0.75218663
98MP0003183_abnormal_peptide_metabolism0.74514472
99MP0000955_abnormal_spinal_cord0.74329311
100MP0005423_abnormal_somatic_nervous0.74041947
101MP0002452_abnormal_antigen_presenting0.73558177
102MP0002723_abnormal_immune_serum0.73432652
103MP0003693_abnormal_embryo_hatching0.71681346
104MP0005000_abnormal_immune_tolerance0.70786028
105MP0005646_abnormal_pituitary_gland0.70500036
106MP0002067_abnormal_sensory_capabilities0.69880559
107MP0001790_abnormal_immune_system0.67989168
108MP0005387_immune_system_phenotype0.67989168
109MP0002233_abnormal_nose_morphology0.67798277
110MP0005171_absent_coat_pigmentation0.66734264
111MP0003436_decreased_susceptibility_to0.66083271
112MP0001905_abnormal_dopamine_level0.65965468
113MP0002752_abnormal_somatic_nervous0.65169665
114MP0003077_abnormal_cell_cycle0.64962544
115MP0002822_catalepsy0.64772688
116MP0001873_stomach_inflammation0.64590283
117MP0003937_abnormal_limbs/digits/tail_de0.64029142
118MP0001119_abnormal_female_reproductive0.63795242
119MP0009643_abnormal_urine_homeostasis0.63597030
120MP0003786_premature_aging0.61533398
121MP0001819_abnormal_immune_cell0.60371514
122MP0000372_irregular_coat_pigmentation0.59849776
123MP0002837_dystrophic_cardiac_calcinosis0.59645646
124MP0005084_abnormal_gallbladder_morpholo0.59553962
125MP0002249_abnormal_larynx_morphology0.59113243
126MP0000049_abnormal_middle_ear0.59087303
127MP0003252_abnormal_bile_duct0.58777968
128MP0002136_abnormal_kidney_physiology0.58375429
129MP0002882_abnormal_neuron_morphology0.58296604
130MP0002420_abnormal_adaptive_immunity0.58288693
131MP0001800_abnormal_humoral_immune0.58000838
132MP0001545_abnormal_hematopoietic_system0.57847955
133MP0005397_hematopoietic_system_phenotyp0.57847955
134MP0001765_abnormal_ion_homeostasis0.57683660
135MP0001968_abnormal_touch/_nociception0.56598267
136MP0004742_abnormal_vestibular_system0.54981576
137MP0002928_abnormal_bile_duct0.54917584
138MP0005671_abnormal_response_to0.52373480
139MP0000015_abnormal_ear_pigmentation0.52331132
140MP0003763_abnormal_thymus_physiology0.51308832
141MP0002132_abnormal_respiratory_system0.48836412
142MP0001845_abnormal_inflammatory_respons0.46598107
143MP0000716_abnormal_immune_system0.44882783
144MP0001853_heart_inflammation0.43788286
145MP0009764_decreased_sensitivity_to0.43198275
146MP0004782_abnormal_surfactant_physiolog0.42374118
147MP0000026_abnormal_inner_ear0.41990063
148MP0002398_abnormal_bone_marrow0.41619690
149MP0001348_abnormal_lacrimal_gland0.41230142
150MP0003699_abnormal_female_reproductive0.41027651
151MP0001727_abnormal_embryo_implantation0.40597465
152MP0009115_abnormal_fat_cell0.39589830
153MP0001764_abnormal_homeostasis0.37615633
154MP0000343_altered_response_to0.36902886
155MP0001440_abnormal_grooming_behavior0.35347588
156MP0005310_abnormal_salivary_gland0.34209704
157MP0000490_abnormal_crypts_of0.33692710
158MP0000313_abnormal_cell_death0.33134134
159MP0008469_abnormal_protein_level0.32890827
160MP0004510_myositis0.32887127
161MP0001963_abnormal_hearing_physiology0.32136414
162MP0005253_abnormal_eye_physiology0.31900124
163MP0001346_abnormal_lacrimal_gland0.31679070
164MP0002429_abnormal_blood_cell0.31137186
165MP0005409_darkened_coat_color0.31105765
166MP0000703_abnormal_thymus_morphology0.30211201
167MP0004808_abnormal_hematopoietic_stem0.29663821
168MP0004233_abnormal_muscle_weight0.29554131
169MP0003724_increased_susceptibility_to0.29005179

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.99131252
2Abnormal respiratory epithelium morphology (HP:0012253)9.19482681
3Abnormal respiratory motile cilium morphology (HP:0005938)9.19482681
4Abnormal ciliary motility (HP:0012262)8.43332653
5Rhinitis (HP:0012384)7.89706507
6Chronic bronchitis (HP:0004469)6.81180222
7Nasal polyposis (HP:0100582)5.64242271
8Infertility (HP:0000789)5.24873137
9Bronchiectasis (HP:0002110)4.72819944
10Abnormality of the nasal mucosa (HP:0000433)4.49454829
11Bronchitis (HP:0012387)4.23867767
12Recurrent sinusitis (HP:0011108)4.11210114
13Nephronophthisis (HP:0000090)4.08846869
14Occipital encephalocele (HP:0002085)3.71012352
15Tubulointerstitial nephritis (HP:0001970)3.44198390
16Recurrent otitis media (HP:0000403)3.17712376
17Chronic hepatic failure (HP:0100626)3.15165307
18Abnormality of the renal medulla (HP:0100957)3.09285526
19Male infertility (HP:0003251)3.08926987
20Abnormal spermatogenesis (HP:0008669)2.93960224
21Medial flaring of the eyebrow (HP:0010747)2.70407754
22Tubular atrophy (HP:0000092)2.64973515
23Chronic otitis media (HP:0000389)2.64878737
24Recurrent bronchitis (HP:0002837)2.52326130
25Tubulointerstitial abnormality (HP:0001969)2.34414204
26Abnormality of midbrain morphology (HP:0002418)2.34375681
27Molar tooth sign on MRI (HP:0002419)2.34375681
28Atelectasis (HP:0100750)2.31551899
29Anencephaly (HP:0002323)2.31358377
30Postaxial foot polydactyly (HP:0001830)2.28000970
31Hyperactive renin-angiotensin system (HP:0000841)2.27709125
32Impulsivity (HP:0100710)2.25739687
33Gonadotropin excess (HP:0000837)2.20078490
34Sclerocornea (HP:0000647)2.19404766
35Male pseudohermaphroditism (HP:0000037)2.17526656
36Median cleft lip (HP:0000161)2.09470265
37Chromosomal breakage induced by crosslinking agents (HP:0003221)2.09213512
38Azoospermia (HP:0000027)2.05597633
39Congenital hepatic fibrosis (HP:0002612)2.03144583
40Furrowed tongue (HP:0000221)2.02528906
41Dyschromatopsia (HP:0007641)2.00552134
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.3596196
43Absent/shortened dynein arms (HP:0200106)12.0032624
44Dynein arm defect of respiratory motile cilia (HP:0012255)12.0032624
45Chromsome breakage (HP:0040012)1.96605257
46Aplasia/Hypoplasia of the spleen (HP:0010451)1.96362361
47Decreased circulating renin level (HP:0003351)1.95514961
48Pancreatic fibrosis (HP:0100732)1.94330981
49Asplenia (HP:0001746)1.92912274
50Stage 5 chronic kidney disease (HP:0003774)1.92849637
51Chronic sinusitis (HP:0011109)1.89361628
52Gait imbalance (HP:0002141)1.86297129
53Facial cleft (HP:0002006)1.86192991
54Congenital primary aphakia (HP:0007707)1.84764880
55Abnormal biliary tract physiology (HP:0012439)1.83726161
56Bile duct proliferation (HP:0001408)1.83726161
57Bell-shaped thorax (HP:0001591)1.79847301
58Aplasia/Hypoplasia of the lens (HP:0008063)1.79493427
59Renal salt wasting (HP:0000127)1.77778272
60Retrobulbar optic neuritis (HP:0100654)1.76802052
61Optic neuritis (HP:0100653)1.76802052
62True hermaphroditism (HP:0010459)1.72622982
63Fibular hypoplasia (HP:0003038)1.71177139
64Abnormal drinking behavior (HP:0030082)1.71019553
65Polydipsia (HP:0001959)1.71019553
66Abnormal rod and cone electroretinograms (HP:0008323)1.70082674
67Absent rod-and cone-mediated responses on ERG (HP:0007688)1.68798273
68Recurrent abscess formation (HP:0002722)1.67602594
69Decreased central vision (HP:0007663)1.63143697
70Preaxial hand polydactyly (HP:0001177)1.62506488
71Nephrogenic diabetes insipidus (HP:0009806)1.60488051
72Abnormality of permanent molar morphology (HP:0011071)1.60308626
73Abnormality of the dental root (HP:0006486)1.60308626
74Taurodontia (HP:0000679)1.60308626
75Abnormality of the renal cortex (HP:0011035)1.59063352
76Postaxial hand polydactyly (HP:0001162)1.57658597
77Hyperkalemia (HP:0002153)1.57438396
78Hypoplasia of the capital femoral epiphysis (HP:0003090)1.55142068
79Prostate neoplasm (HP:0100787)1.54957224
80Polyuria (HP:0000103)1.53479536
81Abnormality of molar morphology (HP:0011070)1.53057826
82Abnormality of molar (HP:0011077)1.53057826
83Hyperaldosteronism (HP:0000859)1.51201678
84Abnormality of renin-angiotensin system (HP:0000847)1.49996486
85Abnormality of the dental pulp (HP:0006479)1.48794741
86Tubulointerstitial fibrosis (HP:0005576)1.48008006
87Aplasia/Hypoplasia of the tongue (HP:0010295)1.47549953
88Abnormality of dentin (HP:0010299)1.47130627
89Abnormality of macular pigmentation (HP:0008002)1.46979571
90Recurrent gram-negative bacterial infections (HP:0005420)1.46814524
91Recurrent bacterial skin infections (HP:0005406)1.46576401
92Abnormality of renal excretion (HP:0011036)1.45891436
93Abnormality of abdominal situs (HP:0011620)1.44810452
94Abdominal situs inversus (HP:0003363)1.44810452
95Aplasia/Hypoplasia of the uvula (HP:0010293)1.42507368
96Choroideremia (HP:0001139)1.42446410
97Renal dysplasia (HP:0000110)1.42253302
98Eczematoid dermatitis (HP:0000976)1.41805524
99Congenital stationary night blindness (HP:0007642)1.41795607
100Supernumerary spleens (HP:0009799)1.41616098
101Orchitis (HP:0100796)1.40541791
102Upper limb muscle weakness (HP:0003484)1.38538326
103Myositis (HP:0100614)1.38496562
104Genital tract atresia (HP:0001827)1.38182611
105Short ribs (HP:0000773)1.36611920
106Transposition of the great arteries (HP:0001669)1.35549071
107Abnormal connection of the cardiac segments (HP:0011545)1.35549071
108Abnormal ventriculo-arterial connection (HP:0011563)1.35549071
109Hypokalemic alkalosis (HP:0001949)1.35480185
110Meckel diverticulum (HP:0002245)1.34180293
111Poor coordination (HP:0002370)1.32862645
112Nephropathy (HP:0000112)1.32533761
113Keratoconjunctivitis (HP:0001096)1.31974382
114Abnormality of chromosome stability (HP:0003220)1.31705248
115Impaired proprioception (HP:0010831)1.29986239
116Chronic obstructive pulmonary disease (HP:0006510)1.29597807
117Obstructive lung disease (HP:0006536)1.29597807
118Absent speech (HP:0001344)1.29576863
119Microglossia (HP:0000171)1.29462819
120Pancreatic cysts (HP:0001737)1.29176175
121Abnormality of chloride homeostasis (HP:0011422)1.29153526
122Vaginal atresia (HP:0000148)1.29039664
123Type 2 muscle fiber atrophy (HP:0003554)1.28509384
124Oculomotor apraxia (HP:0000657)1.28506998
125Cystic liver disease (HP:0006706)1.27700974
126Short thorax (HP:0010306)1.27493281
127Abnormality of the ileum (HP:0001549)1.27077124
128Retinitis pigmentosa (HP:0000510)1.25526642
129Narrow forehead (HP:0000341)1.24432393
130Absent frontal sinuses (HP:0002688)1.24080599
131Abnormal urine output (HP:0012590)1.24001969
132Bony spicule pigmentary retinopathy (HP:0007737)1.23873247
133Cone-rod dystrophy (HP:0000548)1.21270746
134Fetal akinesia sequence (HP:0001989)1.16365744
135Aganglionic megacolon (HP:0002251)1.15538017
136Multicystic kidney dysplasia (HP:0000003)1.14719138
137Prominent nasal bridge (HP:0000426)1.13793329
138Highly arched eyebrow (HP:0002553)1.07719792
139Hyponatremia (HP:0002902)1.07489549
140Anophthalmia (HP:0000528)1.07352213
141Attenuation of retinal blood vessels (HP:0007843)1.02213401
142Hip dysplasia (HP:0001385)1.02027284

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.52770094
2PDK47.52770094
3TESK15.89429011
4PDK24.79823126
5MST44.64624850
6PRKD34.62223528
7ICK3.26934508
8EPHA22.29711719
9PNCK2.28787089
10MAPKAPK32.21106840
11MAP4K21.96601823
12MAPK151.86827440
13DYRK31.86472464
14PTK2B1.76659891
15NEK21.67660007
16TLK11.60624592
17MAP3K141.54784348
18WNK31.54255676
19MAP3K41.52698449
20WNK41.47857895
21RIPK41.47276953
22INSRR1.44089449
23BCR1.37812843
24CASK1.35850129
25STK381.32282291
26NME11.31193493
27CDC71.30451980
28OXSR11.28009677
29IRAK41.26817586
30MAPK131.23666788
31MKNK21.20804680
32STK391.20747640
33DYRK1B1.08014388
34EPHA31.04758383
35TEC1.03447528
36IRAK11.01180737
37ACVR1B0.98676214
38CAMKK20.97054258
39PDK10.95232829
40BRSK20.90309683
41PRKCI0.88920340
42PIM20.85749151
43EIF2AK20.81371302
44STK240.78611347
45MAP3K70.78081566
46STK160.78055544
47SRPK10.76660459
48MAP3K20.76488051
49SIK20.75032951
50ADRBK10.74658305
51NTRK20.73680706
52PLK40.73239972
53NLK0.72714731
54MUSK0.70026761
55PRKCE0.69653432
56TRPM70.69187701
57CSNK1G20.68654175
58BMPR1B0.68405999
59TXK0.66456945
60ATR0.64700795
61EPHA40.64556146
62FER0.64463441
63TSSK60.64359770
64SIK30.62676926
65WEE10.61325777
66IRAK30.60532768
67CAMKK10.59957109
68PAK30.59925512
69MKNK10.58488565
70CHEK20.57237885
71CCNB10.56220126
72MARK30.56081928
73DYRK20.56053220
74TNIK0.55840455
75PLK10.55534833
76ADRBK20.55528986
77STK100.53975704
78BTK0.53669082
79GRK10.52882923
80CHEK10.51944523
81PRKCG0.51258809
82PHKG10.51183940
83PHKG20.51183940
84ERBB20.51008358
85PINK10.50554028
86MAP2K70.48606068
87IRAK20.48453429
88YES10.47170298
89CSNK1A1L0.46978070
90EPHB10.46801718
91PASK0.46185500
92CSNK1G30.45356982
93PRKAA20.44798163
94ERBB30.44508548
95BLK0.44237815
96PKN10.43615674
97PRKACA0.43399406
98ZAK0.43154400
99CAMK2A0.41800652
100TBK10.40940482
101ATM0.40817251
102CSNK1G10.40716439
103VRK10.40222870
104PDPK10.39821506
105CSK0.37736810
106STK110.37052205
107GRK70.36513928
108STK38L0.36370458
109FRK0.35584295
110IKBKB0.35176319
111RPS6KB10.34884357
112TYK20.34815543
113PRKCA0.34593335
114LRRK20.34401916
115BMPR20.33953428
116BMX0.33715519
117WNK10.33061939
118PIM10.32958979
119MAP2K60.32928432
120MAP4K10.31637577
121STK30.31396738
122NEK60.30812460
123NEK90.30296753
124FGFR20.29626815
125DYRK1A0.29454896
126ABL10.29273359
127EEF2K0.28771103
128CHUK0.28596797
129ROCK10.28397602
130PRKAA10.28205396
131NTRK30.26982947
132SGK10.26755870
133CAMK2G0.25681890
134RPS6KA40.25537911
135CAMK1G0.25339603
136RPS6KA50.24674023
137NUAK10.24496318
138TTK0.24024477
139CSNK2A10.23664896
140PAK10.23565068
141TIE10.22100136
142AURKA0.21752674
143PRKCQ0.20873114
144TESK20.20409001
145SYK0.18392583
146PRKCD0.18052509
147TNK20.16647666
148IKBKE0.15178666
149BRAF0.13780173
150AURKB0.13602108
151CSF1R0.13214517
152LMTK20.13002350
153PRKG10.10791525
154LYN0.10585708
155PRKCZ0.10223087
156CSNK2A20.10148547
157GSK3B0.09920349
158MAPKAPK50.09641332
159RPS6KA10.09632874
160CDK30.09551343

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.44362919
2Linoleic acid metabolism_Homo sapiens_hsa005913.37917107
3Vitamin B6 metabolism_Homo sapiens_hsa007503.34831879
4Fatty acid biosynthesis_Homo sapiens_hsa000613.10919493
5Phenylalanine metabolism_Homo sapiens_hsa003602.96711603
6Caffeine metabolism_Homo sapiens_hsa002322.85489152
7Fanconi anemia pathway_Homo sapiens_hsa034602.85026853
8Basal transcription factors_Homo sapiens_hsa030222.71497413
9Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.66416329
10beta-Alanine metabolism_Homo sapiens_hsa004102.52353223
11Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.43837350
12Tyrosine metabolism_Homo sapiens_hsa003502.43229279
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.10915826
14Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.10373985
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.06674563
16Phototransduction_Homo sapiens_hsa047442.00941260
17Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.97451584
18Retinol metabolism_Homo sapiens_hsa008301.93706272
19Ether lipid metabolism_Homo sapiens_hsa005651.92159735
20Glycosaminoglycan degradation_Homo sapiens_hsa005311.80380815
21Homologous recombination_Homo sapiens_hsa034401.76571424
22Arachidonic acid metabolism_Homo sapiens_hsa005901.74873083
23Glucagon signaling pathway_Homo sapiens_hsa049221.71692473
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.70046646
25Butanoate metabolism_Homo sapiens_hsa006501.67527221
26Antigen processing and presentation_Homo sapiens_hsa046121.66890767
27Legionellosis_Homo sapiens_hsa051341.63871093
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.62866469
29DNA replication_Homo sapiens_hsa030301.60768684
30Nicotine addiction_Homo sapiens_hsa050331.53677376
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.52433813
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48684525
33Peroxisome_Homo sapiens_hsa041461.48679418
34Carbohydrate digestion and absorption_Homo sapiens_hsa049731.47580572
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.46859155
36Pyruvate metabolism_Homo sapiens_hsa006201.46305484
37Base excision repair_Homo sapiens_hsa034101.42982269
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.37666345
39Purine metabolism_Homo sapiens_hsa002301.37293352
40Olfactory transduction_Homo sapiens_hsa047401.30582600
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30155967
42Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.28729885
43Nitrogen metabolism_Homo sapiens_hsa009101.25458062
44Non-homologous end-joining_Homo sapiens_hsa034501.25260442
45Tryptophan metabolism_Homo sapiens_hsa003801.25007957
46Huntingtons disease_Homo sapiens_hsa050161.24266997
47Dorso-ventral axis formation_Homo sapiens_hsa043201.22546744
48Salivary secretion_Homo sapiens_hsa049701.17446651
49Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.15364815
50Measles_Homo sapiens_hsa051621.15231134
51Pyrimidine metabolism_Homo sapiens_hsa002401.14566827
52Vitamin digestion and absorption_Homo sapiens_hsa049771.12739910
53Propanoate metabolism_Homo sapiens_hsa006401.10635007
54Amphetamine addiction_Homo sapiens_hsa050311.10611592
55Fatty acid degradation_Homo sapiens_hsa000711.10092448
56Intestinal immune network for IgA production_Homo sapiens_hsa046721.09869348
57Mineral absorption_Homo sapiens_hsa049781.08766402
58Oocyte meiosis_Homo sapiens_hsa041141.08407999
59Glycerolipid metabolism_Homo sapiens_hsa005611.07957550
60PPAR signaling pathway_Homo sapiens_hsa033201.07126346
61Circadian rhythm_Homo sapiens_hsa047101.07031410
62NF-kappa B signaling pathway_Homo sapiens_hsa040641.05825563
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.05094048
64RNA transport_Homo sapiens_hsa030131.02036126
65Primary bile acid biosynthesis_Homo sapiens_hsa001201.00507234
66Selenocompound metabolism_Homo sapiens_hsa004500.96286151
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94558418
68Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.93099349
69Rheumatoid arthritis_Homo sapiens_hsa053230.91075822
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89645353
71Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.88672146
72Primary immunodeficiency_Homo sapiens_hsa053400.87655148
73Herpes simplex infection_Homo sapiens_hsa051680.86873673
74Asthma_Homo sapiens_hsa053100.85671711
75Tight junction_Homo sapiens_hsa045300.82543062
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.82527348
77Allograft rejection_Homo sapiens_hsa053300.82427548
78mRNA surveillance pathway_Homo sapiens_hsa030150.81571529
79Fructose and mannose metabolism_Homo sapiens_hsa000510.81191038
80Systemic lupus erythematosus_Homo sapiens_hsa053220.81085016
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80981363
82Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79665147
83Pentose phosphate pathway_Homo sapiens_hsa000300.79341777
84Insulin secretion_Homo sapiens_hsa049110.76184726
85Influenza A_Homo sapiens_hsa051640.76028576
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75213478
87Phagosome_Homo sapiens_hsa041450.75128454
88Oxidative phosphorylation_Homo sapiens_hsa001900.74927643
89Graft-versus-host disease_Homo sapiens_hsa053320.74824736
90Collecting duct acid secretion_Homo sapiens_hsa049660.72559529
91Cardiac muscle contraction_Homo sapiens_hsa042600.72104618
92Glutathione metabolism_Homo sapiens_hsa004800.72045791
93Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70692016
94Regulation of autophagy_Homo sapiens_hsa041400.69885129
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69567105
96Cocaine addiction_Homo sapiens_hsa050300.69355759
97Basal cell carcinoma_Homo sapiens_hsa052170.69027191
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68175067
99Serotonergic synapse_Homo sapiens_hsa047260.67315725
100Leishmaniasis_Homo sapiens_hsa051400.66067061
101Osteoclast differentiation_Homo sapiens_hsa043800.64804499
102Calcium signaling pathway_Homo sapiens_hsa040200.63913101
103Starch and sucrose metabolism_Homo sapiens_hsa005000.63525346
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62408367
105B cell receptor signaling pathway_Homo sapiens_hsa046620.62073042
106Nucleotide excision repair_Homo sapiens_hsa034200.61145031
107Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59997440
108Malaria_Homo sapiens_hsa051440.59578377
109Ovarian steroidogenesis_Homo sapiens_hsa049130.58830494
110Histidine metabolism_Homo sapiens_hsa003400.57961167
111Metabolic pathways_Homo sapiens_hsa011000.56955241
112Taste transduction_Homo sapiens_hsa047420.56719593
113Renin-angiotensin system_Homo sapiens_hsa046140.55558519
114Autoimmune thyroid disease_Homo sapiens_hsa053200.54907734
115Cell cycle_Homo sapiens_hsa041100.54785220
116Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.54401492
117Drug metabolism - other enzymes_Homo sapiens_hsa009830.54160786
118Salmonella infection_Homo sapiens_hsa051320.53393620
119Hedgehog signaling pathway_Homo sapiens_hsa043400.53280554
120cAMP signaling pathway_Homo sapiens_hsa040240.51772359
121RNA degradation_Homo sapiens_hsa030180.51258045
122Glutamatergic synapse_Homo sapiens_hsa047240.50984320
123Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.50236127
124Protein export_Homo sapiens_hsa030600.49701004
125Sphingolipid metabolism_Homo sapiens_hsa006000.49516289
126Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49355015
127Tuberculosis_Homo sapiens_hsa051520.49294270
128Toxoplasmosis_Homo sapiens_hsa051450.49016055
129Jak-STAT signaling pathway_Homo sapiens_hsa046300.48938640
130Toll-like receptor signaling pathway_Homo sapiens_hsa046200.48724916
131Epstein-Barr virus infection_Homo sapiens_hsa051690.47305514
132NOD-like receptor signaling pathway_Homo sapiens_hsa046210.46992343
133ABC transporters_Homo sapiens_hsa020100.45920221
134Proteasome_Homo sapiens_hsa030500.44701947
135Type I diabetes mellitus_Homo sapiens_hsa049400.44598414
136Estrogen signaling pathway_Homo sapiens_hsa049150.44463183
137Circadian entrainment_Homo sapiens_hsa047130.43680220
138African trypanosomiasis_Homo sapiens_hsa051430.43348033
139Renin secretion_Homo sapiens_hsa049240.43139194
140Mismatch repair_Homo sapiens_hsa034300.42611816
141Viral carcinogenesis_Homo sapiens_hsa052030.40917865
142RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.40356899
143Chemical carcinogenesis_Homo sapiens_hsa052040.40136149
144Other glycan degradation_Homo sapiens_hsa005110.39597296
145Inositol phosphate metabolism_Homo sapiens_hsa005620.38702298
146Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.37667519
147Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35296861
148GABAergic synapse_Homo sapiens_hsa047270.35125353
149Morphine addiction_Homo sapiens_hsa050320.34886459
150TNF signaling pathway_Homo sapiens_hsa046680.34137174
151Arginine and proline metabolism_Homo sapiens_hsa003300.34100080
152SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33579327
153Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33158145
154Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.32108598
155Synaptic vesicle cycle_Homo sapiens_hsa047210.30373869
156Parkinsons disease_Homo sapiens_hsa050120.27960261
157Hippo signaling pathway_Homo sapiens_hsa043900.25850761
158Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24271923
159Bile secretion_Homo sapiens_hsa049760.23153223
160Gastric acid secretion_Homo sapiens_hsa049710.22675556
161Pancreatic secretion_Homo sapiens_hsa049720.21913200
162Axon guidance_Homo sapiens_hsa043600.21302910
163Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.20430011

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