TUBA1A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)9.15561034
2nucleobase catabolic process (GO:0046113)7.15334380
3negative regulation of microtubule polymerization (GO:0031115)6.12266982
4cell migration in hindbrain (GO:0021535)5.91552512
5neuron cell-cell adhesion (GO:0007158)5.73023709
6neuron recognition (GO:0008038)5.26001300
7axonal fasciculation (GO:0007413)5.21005458
8layer formation in cerebral cortex (GO:0021819)5.14501967
9central nervous system projection neuron axonogenesis (GO:0021952)4.98554882
10dendritic spine morphogenesis (GO:0060997)4.94022361
11response to pheromone (GO:0019236)4.58088506
12dendrite morphogenesis (GO:0048813)4.55120532
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.50956262
14vocalization behavior (GO:0071625)4.50890006
15protein localization to synapse (GO:0035418)4.46571087
16axon extension (GO:0048675)4.04704045
17central nervous system neuron axonogenesis (GO:0021955)3.92136845
18regulation of synapse structural plasticity (GO:0051823)3.84541743
19postsynaptic membrane organization (GO:0001941)3.83128027
20positive regulation of synapse assembly (GO:0051965)3.78846308
21hippocampus development (GO:0021766)3.76827805
22establishment of mitochondrion localization (GO:0051654)3.76292409
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.73515420
24regulation of glutamate receptor signaling pathway (GO:1900449)3.70457365
25synaptic vesicle exocytosis (GO:0016079)3.69774360
26transmission of nerve impulse (GO:0019226)3.67670467
27sequestering of actin monomers (GO:0042989)3.67420634
28regulation of short-term neuronal synaptic plasticity (GO:0048172)3.65437653
29positive regulation of mitochondrial fission (GO:0090141)3.56327962
30regulation of microtubule polymerization (GO:0031113)3.55616196
31regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.51445104
32gamma-aminobutyric acid transport (GO:0015812)3.51109014
33exploration behavior (GO:0035640)3.50747637
34neuron projection extension (GO:1990138)3.50658162
35cerebral cortex radially oriented cell migration (GO:0021799)3.48790346
36negative regulation of axon extension (GO:0030517)3.46700956
37substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.46450316
38substrate-independent telencephalic tangential migration (GO:0021826)3.46450316
39positive regulation of synapse maturation (GO:0090129)3.45945935
40mitochondrion transport along microtubule (GO:0047497)3.45703002
41establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.45703002
42negative regulation of axon guidance (GO:1902668)3.44250750
43regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.41324576
44regulation of synaptic vesicle exocytosis (GO:2000300)3.39093731
45nonmotile primary cilium assembly (GO:0035058)3.37728816
46neuron migration (GO:0001764)3.33741603
47limb bud formation (GO:0060174)3.30984971
48positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.30666059
49retinal ganglion cell axon guidance (GO:0031290)3.30633697
50negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.28735450
51negative regulation of axonogenesis (GO:0050771)3.28298272
52locomotory exploration behavior (GO:0035641)3.26685415
53mechanosensory behavior (GO:0007638)3.25617888
54negative regulation of axon extension involved in axon guidance (GO:0048843)3.25612404
55glycosphingolipid biosynthetic process (GO:0006688)3.23610974
56cerebellum development (GO:0021549)3.22162336
57neuronal ion channel clustering (GO:0045161)3.22033551
58presynaptic membrane assembly (GO:0097105)3.21774294
59olfactory bulb development (GO:0021772)3.21091082
60regulation of axon extension (GO:0030516)3.21082215
61presynaptic membrane organization (GO:0097090)3.20611361
62regulation of synapse assembly (GO:0051963)3.20044671
63auditory behavior (GO:0031223)3.18775112
64synaptic vesicle maturation (GO:0016188)3.16445299
65positive regulation of filopodium assembly (GO:0051491)3.15923628
66dendrite development (GO:0016358)3.14964628
67regulation of extent of cell growth (GO:0061387)3.13049020
68synapse assembly (GO:0007416)3.10795253
69regulation of respiratory system process (GO:0044065)3.09129293
70neuronal action potential propagation (GO:0019227)3.07220484
71behavioral response to nicotine (GO:0035095)3.04588744
72adult walking behavior (GO:0007628)3.03650659
73axonogenesis (GO:0007409)3.03017762
74ionotropic glutamate receptor signaling pathway (GO:0035235)3.02577357
75negative regulation of synaptic transmission, GABAergic (GO:0032229)3.01294628
76regulation of synapse organization (GO:0050807)3.00546729
77sympathetic nervous system development (GO:0048485)2.98470611
78innervation (GO:0060384)2.97982597
79protein localization to cilium (GO:0061512)2.97636700
80regulation of axon guidance (GO:1902667)2.95847825
81positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.93318784
82neuron-neuron synaptic transmission (GO:0007270)2.91652649
83neural tube formation (GO:0001841)2.91466183
84glutamate secretion (GO:0014047)2.91222614
85adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.90289400
86negative regulation of dendrite development (GO:2000171)2.90140413
87spinal cord development (GO:0021510)2.90085552
88dopamine receptor signaling pathway (GO:0007212)2.90057119
89neurofilament cytoskeleton organization (GO:0060052)2.89777065
90positive regulation of dendritic spine morphogenesis (GO:0061003)2.89730753
91regulation of collateral sprouting (GO:0048670)2.88815226
92neuron projection morphogenesis (GO:0048812)2.88459675
93cerebral cortex neuron differentiation (GO:0021895)2.87345369
94protein polyglutamylation (GO:0018095)2.87014161
95regulation of synapse maturation (GO:0090128)2.86768707
96proline transport (GO:0015824)2.86650991
97regulation of respiratory gaseous exchange (GO:0043576)2.85304702
98startle response (GO:0001964)2.84629223
99neuromuscular synaptic transmission (GO:0007274)2.84517835
100regulation of synaptic vesicle transport (GO:1902803)2.84042875
101positive regulation of axon extension (GO:0045773)2.83901042
102dendritic spine organization (GO:0097061)2.82695572
103regulation of cAMP-dependent protein kinase activity (GO:2000479)2.82067053
104positive regulation of protein depolymerization (GO:1901881)2.80899583
105glutamate receptor signaling pathway (GO:0007215)2.80746413
106neurotransmitter-gated ion channel clustering (GO:0072578)2.80703061
107clathrin coat assembly (GO:0048268)2.79005640
108regulation of axonogenesis (GO:0050770)2.78261411
109regulation of axon extension involved in axon guidance (GO:0048841)2.78211094
110regulation of filopodium assembly (GO:0051489)2.78048130
111regulation of NFAT protein import into nucleus (GO:0051532)2.78029599
112synapse organization (GO:0050808)2.76989556
113synaptic transmission, cholinergic (GO:0007271)2.76651525
114establishment of nucleus localization (GO:0040023)2.76408612
115chaperone-mediated protein transport (GO:0072321)2.76054287
116homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.76042314
117ganglion development (GO:0061548)2.75511846
118organelle transport along microtubule (GO:0072384)2.74477999
119synaptic transmission, glutamatergic (GO:0035249)2.74141844
120calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.73604077
121negative regulation of oligodendrocyte differentiation (GO:0048715)2.73407749
122neurotransmitter secretion (GO:0007269)2.73273391
123positive regulation of synaptic transmission, GABAergic (GO:0032230)2.73261164
124forebrain neuron differentiation (GO:0021879)2.73165972
125peptidyl-arginine omega-N-methylation (GO:0035247)2.72645209
126response to auditory stimulus (GO:0010996)2.72612474
127regulation of microtubule-based movement (GO:0060632)2.72612130
128regulation of feeding behavior (GO:0060259)2.71648436
129positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.68490256
130epithelial cell differentiation involved in kidney development (GO:0035850)2.67979274
131regulation of cilium movement (GO:0003352)2.66976964
132cerebral cortex cell migration (GO:0021795)2.64691580
133regulation of synaptic transmission, glutamatergic (GO:0051966)2.62317822
134intraciliary transport (GO:0042073)2.59871327
135head development (GO:0060322)2.59519662
136nervous system development (GO:0007399)2.59214501
137epithelial cilium movement (GO:0003351)2.58781978
138* cytoskeleton-dependent intracellular transport (GO:0030705)2.58085669

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.39789512
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.47355179
3GBX2_23144817_ChIP-Seq_PC3_Human3.24922218
4EZH2_27304074_Chip-Seq_ESCs_Mouse3.22253530
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.09089141
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91880570
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.73955588
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.71213664
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.71213664
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.69440233
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59824721
12REST_21632747_ChIP-Seq_MESCs_Mouse2.53854724
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53071855
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.50758444
15CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.48990343
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.48050704
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.42905114
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42286260
19CBX2_27304074_Chip-Seq_ESCs_Mouse2.40011226
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37798552
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.31804675
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.18474504
23BMI1_23680149_ChIP-Seq_NPCS_Mouse2.16209613
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.15227050
25MTF2_20144788_ChIP-Seq_MESCs_Mouse2.11244402
26PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.11190195
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.06857020
28CTBP2_25329375_ChIP-Seq_LNCAP_Human2.01870882
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.98753869
30RNF2_27304074_Chip-Seq_NSC_Mouse1.91409348
31AR_21572438_ChIP-Seq_LNCaP_Human1.87216449
32RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.81789635
33IGF1R_20145208_ChIP-Seq_DFB_Human1.80886928
34ZNF274_21170338_ChIP-Seq_K562_Hela1.78344612
35TAF15_26573619_Chip-Seq_HEK293_Human1.77177423
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.72295788
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71493358
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69983453
39DROSHA_22980978_ChIP-Seq_HELA_Human1.65543619
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.65448210
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.63840289
42RING1B_27294783_Chip-Seq_ESCs_Mouse1.60073644
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.59107132
44RING1B_27294783_Chip-Seq_NPCs_Mouse1.57418002
45OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.55199710
46* RARB_27405468_Chip-Seq_BRAIN_Mouse1.48819820
47EWS_26573619_Chip-Seq_HEK293_Human1.44560412
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.40549423
49ZFP281_18757296_ChIP-ChIP_E14_Mouse1.37203462
50P300_19829295_ChIP-Seq_ESCs_Human1.36892338
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33472299
52* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31361308
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31178696
54* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29052236
55MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.27976591
56POU5F1_16153702_ChIP-ChIP_HESCs_Human1.27871872
57TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26157131
58POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26157131
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25341797
60* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.24873743
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21706244
62TP53_20018659_ChIP-ChIP_R1E_Mouse1.21370645
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20702322
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.20637893
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20418322
66IRF1_19129219_ChIP-ChIP_H3396_Human1.18845537
67CBP_20019798_ChIP-Seq_JUKART_Human1.18072776
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18072776
69SMAD4_21799915_ChIP-Seq_A2780_Human1.17149914
70IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17050760
71SOX2_21211035_ChIP-Seq_LN229_Gbm1.16337503
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15895384
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15384534
74STAT3_23295773_ChIP-Seq_U87_Human1.14949047
75SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12825554
76P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12220926
77HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11940855
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09297512
79TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09296086
80POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08035601
81* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.06208902
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04637892
83YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03815234
84VDR_22108803_ChIP-Seq_LS180_Human1.03584330
85GATA1_26923725_Chip-Seq_HPCs_Mouse1.03581478
86TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03143646
87WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02959151
88CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.02868241
89TCF4_23295773_ChIP-Seq_U87_Human1.02452705
90KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01818696
91TAL1_26923725_Chip-Seq_HPCs_Mouse1.00938969
92* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00059792
93NANOG_18555785_Chip-Seq_ESCs_Mouse0.99914116
94* AR_25329375_ChIP-Seq_VCAP_Human0.98200593
95AHR_22903824_ChIP-Seq_MCF-7_Human0.97376841
96SOX9_26525672_Chip-Seq_HEART_Mouse0.97096831
97RUNX2_22187159_ChIP-Seq_PCA_Human0.96637531
98* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.96551020
99AR_19668381_ChIP-Seq_PC3_Human0.95824599
100LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95810149
101ARNT_22903824_ChIP-Seq_MCF-7_Human0.95039605
102PIAS1_25552417_ChIP-Seq_VCAP_Human0.94868741
103EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94617589
104TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.94614253
105FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94356486
106BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.93893372
107TP53_22573176_ChIP-Seq_HFKS_Human0.93495743
108JUN_21703547_ChIP-Seq_K562_Human0.92100541
109* POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.91995244
110MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91958714
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91127774
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90464604
113SMAD3_21741376_ChIP-Seq_ESCs_Human0.89258515
114ER_23166858_ChIP-Seq_MCF-7_Human0.88145399
115NR3C1_21868756_ChIP-Seq_MCF10A_Human0.87791701
116SALL1_21062744_ChIP-ChIP_HESCs_Human0.87384887
117KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87038045
118KDM2B_26808549_Chip-Seq_K562_Human0.86968026
119DNAJC2_21179169_ChIP-ChIP_NT2_Human0.86793547
120WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85587098
121SOX2_16153702_ChIP-ChIP_HESCs_Human0.85329923
122FUS_26573619_Chip-Seq_HEK293_Human0.85266780
123GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84176462

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.08228609
2MP0004859_abnormal_synaptic_plasticity3.81727802
3MP0000778_abnormal_nervous_system3.69216206
4MP0005423_abnormal_somatic_nervous3.59253884
5MP0006276_abnormal_autonomic_nervous3.57533348
6MP0004270_analgesia3.42463490
7MP0003635_abnormal_synaptic_transmissio2.84143965
8MP0002184_abnormal_innervation2.68086948
9MP0002734_abnormal_mechanical_nocicepti2.67961038
10MP0001968_abnormal_touch/_nociception2.63433309
11MP0002735_abnormal_chemical_nociception2.60989853
12* MP0002063_abnormal_learning/memory/cond2.55534035
13MP0002733_abnormal_thermal_nociception2.30746208
14MP0001529_abnormal_vocalization2.25085359
15MP0000569_abnormal_digit_pigmentation2.07428892
16MP0002736_abnormal_nociception_after2.04827014
17MP0009745_abnormal_behavioral_response2.03772642
18* MP0002572_abnormal_emotion/affect_behav2.00330723
19MP0002102_abnormal_ear_morphology1.98278569
20MP0003122_maternal_imprinting1.98076745
21MP0004858_abnormal_nervous_system1.91483765
22MP0001970_abnormal_pain_threshold1.91082458
23MP0001984_abnormal_olfaction1.90412943
24MP0000955_abnormal_spinal_cord1.87194283
25MP0001440_abnormal_grooming_behavior1.85426549
26MP0001486_abnormal_startle_reflex1.84913404
27MP0002064_seizures1.84542720
28* MP0004811_abnormal_neuron_physiology1.81143214
29MP0002751_abnormal_autonomic_nervous1.76872746
30* MP0002557_abnormal_social/conspecific_i1.74141767
31MP0005645_abnormal_hypothalamus_physiol1.72885902
32MP0008789_abnormal_olfactory_epithelium1.70511703
33MP0000537_abnormal_urethra_morphology1.67528000
34MP0002067_abnormal_sensory_capabilities1.66993069
35* MP0002882_abnormal_neuron_morphology1.64593696
36MP0005394_taste/olfaction_phenotype1.58314514
37MP0005499_abnormal_olfactory_system1.58314514
38MP0002638_abnormal_pupillary_reflex1.58272062
39MP0002272_abnormal_nervous_system1.56656366
40MP0004924_abnormal_behavior1.55864536
41MP0005386_behavior/neurological_phenoty1.55864536
42MP0003861_abnormal_nervous_system1.48016689
43MP0008877_abnormal_DNA_methylation1.46132552
44* MP0002152_abnormal_brain_morphology1.46065824
45MP0001905_abnormal_dopamine_level1.45861297
46MP0004742_abnormal_vestibular_system1.44100847
47MP0000631_abnormal_neuroendocrine_gland1.43967014
48MP0009046_muscle_twitch1.42972395
49MP0005551_abnormal_eye_electrophysiolog1.37214461
50MP0002653_abnormal_ependyma_morphology1.35493381
51MP0009379_abnormal_foot_pigmentation1.30885975
52MP0002752_abnormal_somatic_nervous1.29864429
53MP0001188_hyperpigmentation1.22945512
54MP0005253_abnormal_eye_physiology1.21265241
55* MP0002066_abnormal_motor_capabilities/c1.20109882
56MP0009780_abnormal_chondrocyte_physiolo1.17997446
57MP0004885_abnormal_endolymph1.17974599
58MP0010386_abnormal_urinary_bladder1.15343822
59MP0000751_myopathy1.11796338
60MP0003938_abnormal_ear_development1.10627339
61MP0003890_abnormal_embryonic-extraembry1.10100290
62MP0003329_amyloid_beta_deposits1.09282919
63MP0003121_genomic_imprinting1.08610260
64MP0010030_abnormal_orbit_morphology1.08018055
65MP0005187_abnormal_penis_morphology1.06358085
66MP0003787_abnormal_imprinting1.06296445
67MP0001502_abnormal_circadian_rhythm1.01355584
68MP0000049_abnormal_middle_ear1.01078540
69MP0000538_abnormal_urinary_bladder1.00708642
70MP0003011_delayed_dark_adaptation1.00168266
71MP0006292_abnormal_olfactory_placode0.99710153
72MP0005646_abnormal_pituitary_gland0.99191645
73MP0000026_abnormal_inner_ear0.98862344
74MP0003119_abnormal_digestive_system0.98668519
75MP0004142_abnormal_muscle_tone0.97590515
76MP0002822_catalepsy0.96792146
77MP0003385_abnormal_body_wall0.93678860
78MP0003315_abnormal_perineum_morphology0.93160954
79MP0008569_lethality_at_weaning0.92865162
80MP0002909_abnormal_adrenal_gland0.92208255
81MP0002938_white_spotting0.91084136
82MP0004133_heterotaxia0.90684033
83MP0003942_abnormal_urinary_system0.89915894
84MP0001299_abnormal_eye_distance/0.89360325
85MP0003634_abnormal_glial_cell0.88847295
86MP0002069_abnormal_eating/drinking_beha0.88700523
87MP0002081_perinatal_lethality0.87733942
88MP0000534_abnormal_ureter_morphology0.86985934
89MP0003137_abnormal_impulse_conducting0.84499131
90MP0004145_abnormal_muscle_electrophysio0.82822555
91MP0001986_abnormal_taste_sensitivity0.82803097
92MP0001485_abnormal_pinna_reflex0.82720986
93MP0001963_abnormal_hearing_physiology0.82552568
94MP0002229_neurodegeneration0.82449995
95MP0008995_early_reproductive_senescence0.82041643
96MP0006072_abnormal_retinal_apoptosis0.81076505
97MP0002928_abnormal_bile_duct0.80763346
98MP0002282_abnormal_trachea_morphology0.77376974
99MP0005084_abnormal_gallbladder_morpholo0.77004107
100MP0003136_yellow_coat_color0.75061332
101MP0001943_abnormal_respiration0.75054613
102MP0005391_vision/eye_phenotype0.74179155
103MP0000566_synostosis0.73087777
104MP0002234_abnormal_pharynx_morphology0.73022409
105MP0002116_abnormal_craniofacial_bone0.72695445
106MP0000647_abnormal_sebaceous_gland0.72678536
107MP0001293_anophthalmia0.71998709
108MP0003937_abnormal_limbs/digits/tail_de0.71248359
109MP0002233_abnormal_nose_morphology0.70462046
110MP0005248_abnormal_Harderian_gland0.69666042
111MP0003633_abnormal_nervous_system0.67791983
112MP0003755_abnormal_palate_morphology0.67749094
113MP0010770_preweaning_lethality0.66958138
114MP0002082_postnatal_lethality0.66958138
115MP0001501_abnormal_sleep_pattern0.66895142
116MP0003123_paternal_imprinting0.66665219
117MP0001348_abnormal_lacrimal_gland0.65906673
118MP0004085_abnormal_heartbeat0.65058377
119MP0005195_abnormal_posterior_eye0.65016398

Predicted human phenotypes

RankGene SetZ-score
1Limb dystonia (HP:0002451)4.65230764
2Myokymia (HP:0002411)4.59353501
3Polyphagia (HP:0002591)3.75656117
4Amyotrophic lateral sclerosis (HP:0007354)3.50401148
5Amblyopia (HP:0000646)3.40728837
6Ankle clonus (HP:0011448)3.38910964
7Failure to thrive in infancy (HP:0001531)3.36124955
8Focal seizures (HP:0007359)3.33056662
9Abnormality of the corticospinal tract (HP:0002492)3.32316774
10Medial flaring of the eyebrow (HP:0010747)3.32304659
11Retinal dysplasia (HP:0007973)3.27180040
12Mutism (HP:0002300)3.16889907
13Insidious onset (HP:0003587)3.16447285
14Termporal pattern (HP:0011008)3.16447285
15Congenital primary aphakia (HP:0007707)3.16116850
16Nephrogenic diabetes insipidus (HP:0009806)3.08833198
17Progressive cerebellar ataxia (HP:0002073)3.04471670
18Excessive salivation (HP:0003781)3.03615222
19Drooling (HP:0002307)3.03615222
20True hermaphroditism (HP:0010459)3.02174055
21Abnormality of midbrain morphology (HP:0002418)2.98727627
22Molar tooth sign on MRI (HP:0002419)2.98727627
23Supranuclear gaze palsy (HP:0000605)2.96828973
24Focal motor seizures (HP:0011153)2.91470494
25Shoulder girdle muscle weakness (HP:0003547)2.88994410
26Exotropia (HP:0000577)2.88467927
27Pancreatic fibrosis (HP:0100732)2.88394390
28Cortical dysplasia (HP:0002539)2.81727223
29* Aplasia/Hypoplasia of the brainstem (HP:0007362)2.81378442
30* Hypoplasia of the brainstem (HP:0002365)2.81378442
31Pancreatic cysts (HP:0001737)2.80532079
32Genital tract atresia (HP:0001827)2.72290712
33Vaginal atresia (HP:0000148)2.71968514
34Nephronophthisis (HP:0000090)2.71462238
35Broad-based gait (HP:0002136)2.68513406
36Urinary urgency (HP:0000012)2.61731745
37Epileptic encephalopathy (HP:0200134)2.61406561
38Agitation (HP:0000713)2.55108323
39Specific learning disability (HP:0001328)2.54042052
40Gait imbalance (HP:0002141)2.51570161
41Akinesia (HP:0002304)2.47426690
42Abnormal eating behavior (HP:0100738)2.47100787
43Visual hallucinations (HP:0002367)2.47056186
44* Lissencephaly (HP:0001339)2.44430877
45Wrist flexion contracture (HP:0001239)2.43819027
46Morphological abnormality of the pyramidal tract (HP:0002062)2.41701665
47Spastic gait (HP:0002064)2.41135173
48Esotropia (HP:0000565)2.39702440
49Megalencephaly (HP:0001355)2.38823447
50Pheochromocytoma (HP:0002666)2.35603744
51Abnormality of the labia minora (HP:0012880)2.34105975
52Chronic hepatic failure (HP:0100626)2.30468365
53Sleep apnea (HP:0010535)2.27778619
54EEG with generalized epileptiform discharges (HP:0011198)2.25487261
55Narrow forehead (HP:0000341)2.24580960
56Hypsarrhythmia (HP:0002521)2.23222012
57Progressive inability to walk (HP:0002505)2.22810636
58* Pachygyria (HP:0001302)2.21999212
59Degeneration of the lateral corticospinal tracts (HP:0002314)2.20759926
60Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.20759926
61Poor coordination (HP:0002370)2.20294117
62Epileptiform EEG discharges (HP:0011182)2.19213599
63Atonic seizures (HP:0010819)2.18782998
64Abnormality of the renal medulla (HP:0100957)2.17173295
65Febrile seizures (HP:0002373)2.16952364
66Hyperventilation (HP:0002883)2.16444298
67Postaxial hand polydactyly (HP:0001162)2.15362929
68Hemiparesis (HP:0001269)2.13814218
69Anencephaly (HP:0002323)2.12175294
70Abnormal hair whorl (HP:0010721)2.10640366
71Type II lissencephaly (HP:0007260)2.09439745
72Hypoventilation (HP:0002791)2.07580719
73Impaired vibration sensation in the lower limbs (HP:0002166)2.07143283
74Abnormality of salivation (HP:0100755)2.06159523
75Morphological abnormality of the middle ear (HP:0008609)2.05937178
76Lower limb muscle weakness (HP:0007340)2.05551570
77Oligodactyly (hands) (HP:0001180)2.05022009
78Neuroendocrine neoplasm (HP:0100634)2.04698949
79Atrophy/Degeneration involving motor neurons (HP:0007373)2.02390391
80Occipital encephalocele (HP:0002085)2.01934241
81Action tremor (HP:0002345)2.01865945
82Hyperthyroidism (HP:0000836)2.01150557
83Dialeptic seizures (HP:0011146)2.00879814
84Optic nerve hypoplasia (HP:0000609)1.99767398
85Poor suck (HP:0002033)1.99327403
86Ulnar claw (HP:0001178)1.99065252
87Sclerocornea (HP:0000647)1.98608997
88Insomnia (HP:0100785)1.98551745
89Sacral dimple (HP:0000960)1.98146358
90Sporadic (HP:0003745)1.97269997
91Hip dysplasia (HP:0001385)1.97083828
92Truncal ataxia (HP:0002078)1.96796469
93Hyperacusis (HP:0010780)1.95684078
94Torticollis (HP:0000473)1.94550378
95Urinary bladder sphincter dysfunction (HP:0002839)1.94546856
96Inappropriate behavior (HP:0000719)1.93837947
97Hepatoblastoma (HP:0002884)1.93567836
98Cerebral inclusion bodies (HP:0100314)1.92699343
99Neurofibrillary tangles (HP:0002185)1.91891941
100Pendular nystagmus (HP:0012043)1.91756652
101Fetal akinesia sequence (HP:0001989)1.89530957
102Intestinal atresia (HP:0011100)1.89362901
103Apathy (HP:0000741)1.89088515
104Micropenis (HP:0000054)1.88692193
105Elfin facies (HP:0004428)1.87673794
106Intellectual disability, moderate (HP:0002342)1.87435127
107Renal hypoplasia (HP:0000089)1.86446407
108Absence seizures (HP:0002121)1.86172761
109Hypothermia (HP:0002045)1.85509859
110Heterochromia iridis (HP:0001100)1.85309827
111Labial hypoplasia (HP:0000066)1.84529745
112Abnormality of the lower motor neuron (HP:0002366)1.84392397
113Cystic liver disease (HP:0006706)1.84385532
114Broad foot (HP:0001769)1.84266209
115* Hypoplasia of the corpus callosum (HP:0002079)1.84160078
116Narrow nasal bridge (HP:0000446)1.83927990
117Rimmed vacuoles (HP:0003805)1.83415230
118Poor eye contact (HP:0000817)1.83361845
119Postaxial foot polydactyly (HP:0001830)1.83206819
120* Polymicrogyria (HP:0002126)1.81191575
121High anterior hairline (HP:0009890)1.81111184
122Autism (HP:0000717)1.81102047
123* Spastic tetraplegia (HP:0002510)1.80765995
124Focal dystonia (HP:0004373)1.80664896
125Generalized hypotonia (HP:0001290)1.80170431
126Growth hormone deficiency (HP:0000824)1.79794765
127Genetic anticipation (HP:0003743)1.78307197
128Abnormality of the musculature of the pelvis (HP:0001469)1.78106189
129Abnormality of the hip-girdle musculature (HP:0001445)1.78106189
130Pelvic girdle muscle weakness (HP:0003749)1.76819694
131Aplasia/Hypoplasia of the lens (HP:0008063)1.76671525
132Generalized tonic-clonic seizures (HP:0002069)1.76375231
133Inability to walk (HP:0002540)1.75479871
134Protruding tongue (HP:0010808)1.75023226
135Overriding aorta (HP:0002623)1.74843239
136Absent speech (HP:0001344)1.74458616
137Paraplegia (HP:0010550)1.71775500
138Decreased testicular size (HP:0008734)1.71494697
139Impaired pain sensation (HP:0007328)1.71267180
140Abnormal respiratory epithelium morphology (HP:0012253)1.69741960
141Abnormal respiratory motile cilium morphology (HP:0005938)1.69741960
142Aplasia/Hypoplasia of the tongue (HP:0010295)1.69433672
143Optic nerve coloboma (HP:0000588)1.69099581
144Decreased muscle mass (HP:0003199)1.67453282
145Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.67107031

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK17.30410367
2DYRK23.60680824
3MAPK133.06553583
4NTRK22.71579707
5MINK12.46468186
6CASK2.39319223
7UHMK12.32891502
8ERBB32.29974473
9MAP3K42.24352108
10LIMK12.22732959
11MAP3K92.19193642
12KSR12.17513883
13MAP4K22.10464404
14TRIM282.04421272
15EPHB22.03881936
16MAP2K71.99390356
17NTRK31.96923647
18BCR1.95058280
19SIK21.91831293
20PHKG21.82712347
21PHKG11.82712347
22SIK31.79098674
23PINK11.73603656
24PAK61.61586013
25WNK31.49452952
26PNCK1.47657011
27DAPK21.41707028
28CSNK1G21.40206735
29CSNK1G31.35287400
30TYRO31.34203381
31MAP3K121.32283038
32BMPR1B1.29675256
33CDK51.27340774
34EPHA41.27093523
35TNIK1.17085324
36CDK181.12927891
37LATS21.08376206
38CDK141.07481819
39DYRK1A1.07286746
40CSNK1A1L1.04855653
41CDK151.03056254
42MAP2K41.01595493
43FGFR21.01562366
44PAK30.97924876
45ICK0.94084135
46NTRK10.93783588
47CDK11A0.91544502
48PLK20.90075141
49ADRBK20.89922701
50PKN10.87465159
51MARK20.84978078
52CSNK1G10.84721841
53GRK50.83048394
54SGK2230.81560476
55SGK4940.81560476
56PRKCZ0.81522411
57RPS6KA20.79678209
58PRKCG0.78342864
59WNK40.76239219
60RPS6KA40.73158135
61PRPF4B0.72427255
62FRK0.71739224
63DAPK10.71526914
64DYRK30.71052977
65CAMKK20.68401553
66MAPK150.67878296
67ERBB20.67448583
68CDK190.67316955
69ADRBK10.66810240
70IRAK20.63593763
71BCKDK0.62847899
72TESK10.62393878
73NME10.60977599
74GRK10.59713176
75RET0.59183489
76CAMK2B0.58698955
77CAMK2A0.57920616
78ROCK10.57004212
79MAPK90.56113460
80INSRR0.55203360
81ROCK20.54404201
82MAPK40.51557444
83KSR20.49353125
84CAMK1G0.48078803
85PRKCE0.46791739
86PRKACA0.45100970
87SRPK10.44468005
88CSNK1D0.43465065
89PRKD30.43294434
90FGR0.40856465
91STK110.40767563
92YES10.39925285
93MKNK20.39215800
94ILK0.39091878
95PRKAA10.37960160
96CAMKK10.37380098
97FYN0.37132964
98DYRK1B0.36296499
99CCNB10.35693989
100EPHB10.35069116
101PRKACB0.34883629
102CSNK1A10.34736115
103PRKG10.34700142
104TESK20.34145571
105EPHA30.33847675
106STK390.32342574
107AURKA0.32183492
108MAP3K60.32138497
109CAMK40.32091385
110MAPK80.31914972
111STK160.31242454
112OXSR10.30553409
113CAMK10.30362959
114MAP2K10.29583978
115CSNK1E0.28667697
116PRKCI0.27282657
117PRKCB0.25975747
118CDC42BPA0.25472123
119TGFBR10.25430368
120SGK20.25219558
121MAPK120.25021271
122TSSK60.24981854
123CAMK2D0.24894854
124FGFR10.24118235
125RPS6KA30.23797810
126CAMK2G0.23230766
127BRD40.23021935
128PRKACG0.23001042
129GRK70.22770881
130GSK3B0.22573642

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.23128806
2Nicotine addiction_Homo sapiens_hsa050333.07804607
3Axon guidance_Homo sapiens_hsa043603.01034069
4Synaptic vesicle cycle_Homo sapiens_hsa047212.74718494
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.41257092
6Dopaminergic synapse_Homo sapiens_hsa047282.21747693
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.09242759
8Glutamatergic synapse_Homo sapiens_hsa047242.05486369
9GABAergic synapse_Homo sapiens_hsa047272.01214452
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.00601763
11Circadian entrainment_Homo sapiens_hsa047131.92335375
12Cholinergic synapse_Homo sapiens_hsa047251.91548531
13Olfactory transduction_Homo sapiens_hsa047401.86598573
14Serotonergic synapse_Homo sapiens_hsa047261.83259103
15Morphine addiction_Homo sapiens_hsa050321.75804806
16Cocaine addiction_Homo sapiens_hsa050301.70509197
17Protein export_Homo sapiens_hsa030601.65807719
18Taste transduction_Homo sapiens_hsa047421.63064365
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.61399357
20Colorectal cancer_Homo sapiens_hsa052101.54417290
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.54219294
22* Gap junction_Homo sapiens_hsa045401.51928764
23Amphetamine addiction_Homo sapiens_hsa050311.51431503
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.49843609
25Long-term potentiation_Homo sapiens_hsa047201.46917812
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.45941660
27Parkinsons disease_Homo sapiens_hsa050121.43408860
28Long-term depression_Homo sapiens_hsa047301.38967791
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.37956564
30Endometrial cancer_Homo sapiens_hsa052131.37064579
31Oxidative phosphorylation_Homo sapiens_hsa001901.36610990
32ErbB signaling pathway_Homo sapiens_hsa040121.34298289
33Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.30774898
34Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.29433846
35Cardiac muscle contraction_Homo sapiens_hsa042601.27542610
36Insulin secretion_Homo sapiens_hsa049111.26860223
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.25929460
38Alzheimers disease_Homo sapiens_hsa050101.23758314
39Oxytocin signaling pathway_Homo sapiens_hsa049211.17017827
40Collecting duct acid secretion_Homo sapiens_hsa049661.16790257
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15670921
42* Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.14919134
43Hedgehog signaling pathway_Homo sapiens_hsa043401.14881085
44Renin secretion_Homo sapiens_hsa049241.13557787
45Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.12123296
46Renal cell carcinoma_Homo sapiens_hsa052111.10205068
47Basal cell carcinoma_Homo sapiens_hsa052171.09939507
48Melanogenesis_Homo sapiens_hsa049161.09565348
49Alcoholism_Homo sapiens_hsa050341.08682286
50GnRH signaling pathway_Homo sapiens_hsa049121.08029318
51Phototransduction_Homo sapiens_hsa047441.06472721
52Huntingtons disease_Homo sapiens_hsa050161.05127909
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04191089
54Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03182817
55Glioma_Homo sapiens_hsa052141.02896874
56Steroid biosynthesis_Homo sapiens_hsa001001.02839658
57Vibrio cholerae infection_Homo sapiens_hsa051101.02312519
58Wnt signaling pathway_Homo sapiens_hsa043100.98483450
59Viral myocarditis_Homo sapiens_hsa054160.97714827
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.95929150
61Regulation of autophagy_Homo sapiens_hsa041400.95776156
62Hippo signaling pathway_Homo sapiens_hsa043900.94388298
63Oocyte meiosis_Homo sapiens_hsa041140.93922323
64Estrogen signaling pathway_Homo sapiens_hsa049150.93279208
65Salivary secretion_Homo sapiens_hsa049700.92361308
66Gastric acid secretion_Homo sapiens_hsa049710.91714041
67Ether lipid metabolism_Homo sapiens_hsa005650.86061199
68Type II diabetes mellitus_Homo sapiens_hsa049300.85764318
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82670074
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78469557
71Basal transcription factors_Homo sapiens_hsa030220.77885922
72Propanoate metabolism_Homo sapiens_hsa006400.76437396
73Butanoate metabolism_Homo sapiens_hsa006500.75971007
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75253153
75VEGF signaling pathway_Homo sapiens_hsa043700.73766787
76Calcium signaling pathway_Homo sapiens_hsa040200.73572288
77Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.73171355
78Ras signaling pathway_Homo sapiens_hsa040140.70834154
79Choline metabolism in cancer_Homo sapiens_hsa052310.70763241
80MAPK signaling pathway_Homo sapiens_hsa040100.69666580
81Linoleic acid metabolism_Homo sapiens_hsa005910.69089380
82Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68682104
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.67366694
84Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.67231349
85Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67018944
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63711016
87cAMP signaling pathway_Homo sapiens_hsa040240.61492497
88* Phagosome_Homo sapiens_hsa041450.59985620
89Prion diseases_Homo sapiens_hsa050200.59755238
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.58794281
91mRNA surveillance pathway_Homo sapiens_hsa030150.58028981
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57064698
93Rap1 signaling pathway_Homo sapiens_hsa040150.57018122
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56866063
95Insulin signaling pathway_Homo sapiens_hsa049100.56652194
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55665208
97Endocytosis_Homo sapiens_hsa041440.54708889
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54093201
99Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53615586
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53271717
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.53229848
102Notch signaling pathway_Homo sapiens_hsa043300.53022070
103Tight junction_Homo sapiens_hsa045300.52423403
104Peroxisome_Homo sapiens_hsa041460.52030163
105Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51332898
106Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50360949
107Circadian rhythm_Homo sapiens_hsa047100.49920037
108Fatty acid elongation_Homo sapiens_hsa000620.47730875
109Dilated cardiomyopathy_Homo sapiens_hsa054140.47369903
110Non-small cell lung cancer_Homo sapiens_hsa052230.46517822
111Melanoma_Homo sapiens_hsa052180.45650604
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45639735
113Dorso-ventral axis formation_Homo sapiens_hsa043200.45522875
114mTOR signaling pathway_Homo sapiens_hsa041500.45053163
115Tryptophan metabolism_Homo sapiens_hsa003800.43333765
116Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42548388
117beta-Alanine metabolism_Homo sapiens_hsa004100.41623096
118Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41332684
119Fatty acid metabolism_Homo sapiens_hsa012120.41236480
120Pancreatic cancer_Homo sapiens_hsa052120.40779516
121AMPK signaling pathway_Homo sapiens_hsa041520.39940212
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35713592
123Ovarian steroidogenesis_Homo sapiens_hsa049130.35212679
124Fanconi anemia pathway_Homo sapiens_hsa034600.34993497
125RNA degradation_Homo sapiens_hsa030180.34357000
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25946372
127Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.25648180
128Carbohydrate digestion and absorption_Homo sapiens_hsa049730.25451065
129Metabolic pathways_Homo sapiens_hsa011000.23627692

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