TUBAL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lipoprotein transport (GO:0042953)7.08272112
2intestinal absorption (GO:0050892)7.04898673
3NADH metabolic process (GO:0006734)6.98935454
4epoxygenase P450 pathway (GO:0019373)6.62305960
5fat-soluble vitamin biosynthetic process (GO:0042362)6.25498979
6angiotensin maturation (GO:0002003)6.19806033
7intestinal cholesterol absorption (GO:0030299)6.08270981
8regulation of female gonad development (GO:2000194)5.65864117
9hormone catabolic process (GO:0042447)5.53827710
10regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.41852891
11endocrine process (GO:0050886)5.41852891
12regulation of systemic arterial blood pressure by hormone (GO:0001990)5.41852891
13cellular glucuronidation (GO:0052695)5.39072323
14fructose metabolic process (GO:0006000)5.36948527
15uronic acid metabolic process (GO:0006063)5.24519948
16glucuronate metabolic process (GO:0019585)5.24519948
17piRNA metabolic process (GO:0034587)5.13440733
18regulation of triglyceride catabolic process (GO:0010896)5.08077979
19sulfate transmembrane transport (GO:1902358)5.00872174
20bile acid and bile salt transport (GO:0015721)4.85510538
21regulation of systemic arterial blood pressure (GO:0003073)4.83909560
22drug metabolic process (GO:0017144)4.79978448
23regulation of cGMP biosynthetic process (GO:0030826)4.64116165
24vitamin A metabolic process (GO:0006776)4.63441190
25very-low-density lipoprotein particle assembly (GO:0034379)4.52819893
26adhesion of symbiont to host cell (GO:0044650)4.52680178
27virion attachment to host cell (GO:0019062)4.52680178
28regulation of cellular extravasation (GO:0002691)4.49513271
29urea cycle (GO:0000050)4.41048723
30glycine transport (GO:0015816)4.37160586
31flavonoid metabolic process (GO:0009812)4.34043287
32renal system process involved in regulation of blood volume (GO:0001977)4.32421610
33phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)4.31270509
34sulfate transport (GO:0008272)4.29911138
35regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.29048207
36homocysteine metabolic process (GO:0050667)4.19088925
37regulation of vitamin metabolic process (GO:0030656)4.18027436
38urea metabolic process (GO:0019627)4.16830185
39glycerophospholipid catabolic process (GO:0046475)4.14228684
40diacylglycerol metabolic process (GO:0046339)4.13920413
41vitamin transmembrane transport (GO:0035461)4.13715727
42plasma lipoprotein particle assembly (GO:0034377)4.08003754
43DNA damage induced protein phosphorylation (GO:0006975)4.02243753
44female gamete generation (GO:0007292)4.00658525
45peptide hormone processing (GO:0016486)3.99226601
46regulation of meiosis (GO:0040020)3.96369084
47glycolipid catabolic process (GO:0019377)3.93160387
48glycosphingolipid catabolic process (GO:0046479)3.90459418
49drug transmembrane transport (GO:0006855)3.86490074
50negative regulation of smooth muscle cell differentiation (GO:0051151)3.86352901
51sperm capacitation (GO:0048240)3.85963234
52cellular anion homeostasis (GO:0030002)3.85208556
53antibacterial humoral response (GO:0019731)3.84364506
54parturition (GO:0007567)3.84056793
55peptide catabolic process (GO:0043171)3.81422978
563-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.80749986
57purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.80749986
58regulation of cGMP metabolic process (GO:0030823)3.77343151
59nitrogen cycle metabolic process (GO:0071941)3.76716088
60meiotic chromosome segregation (GO:0045132)3.74820339
61negative regulation of meiosis (GO:0045835)3.74028676
62protein-lipid complex assembly (GO:0065005)3.72546468
63regulation of guanylate cyclase activity (GO:0031282)3.70863798
64adhesion of symbiont to host (GO:0044406)3.67166262
65fat-soluble vitamin metabolic process (GO:0006775)3.66990176
66cellular response to nitric oxide (GO:0071732)3.66765115
67antimicrobial humoral response (GO:0019730)3.66572527
68drug transport (GO:0015893)3.65969728
69nucleoside diphosphate biosynthetic process (GO:0009133)3.64362047
70drug catabolic process (GO:0042737)3.59300364
71bile acid metabolic process (GO:0008206)3.56172602
72vitamin transport (GO:0051180)3.53953319
73negative regulation of hormone biosynthetic process (GO:0032353)3.53249321
74negative regulation of hormone metabolic process (GO:0032351)3.53249321
75DNA methylation involved in gamete generation (GO:0043046)3.52494703
76intestinal epithelial cell development (GO:0060576)3.48862726
77cobalamin metabolic process (GO:0009235)3.48448704
78glutamine family amino acid biosynthetic process (GO:0009084)3.45875818
79glycerol metabolic process (GO:0006071)3.45373178
80arginine metabolic process (GO:0006525)3.45005365
81negative regulation of keratinocyte proliferation (GO:0010839)3.44074259
82labyrinthine layer development (GO:0060711)3.43794067
83digestive system process (GO:0022600)3.42674305
84proline biosynthetic process (GO:0006561)3.38797948
85citrulline metabolic process (GO:0000052)3.36427772
86regulation of cholesterol homeostasis (GO:2000188)3.36367146
87meiotic cell cycle (GO:0051321)3.35521265
88positive regulation of cGMP biosynthetic process (GO:0030828)3.35180490
89heme transport (GO:0015886)3.32858655
90phenol-containing compound catabolic process (GO:0019336)3.32646159
91regulation of meiotic cell cycle (GO:0051445)3.32637817
92sulfation (GO:0051923)3.31739672
93very long-chain fatty acid metabolic process (GO:0000038)3.29538297
94midgut development (GO:0007494)3.29507206
95alkaloid metabolic process (GO:0009820)3.26956533
96lipoprotein metabolic process (GO:0042157)3.26836771
97diol metabolic process (GO:0034311)3.26314654
98positive regulation of pseudopodium assembly (GO:0031274)3.26225729
99urate metabolic process (GO:0046415)3.25934793
100multicellular organism reproduction (GO:0032504)3.22833357
101sulfur compound transport (GO:0072348)3.22155312
102exogenous drug catabolic process (GO:0042738)3.21063006
103glycosylceramide metabolic process (GO:0006677)3.20900102
104fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.20631426
105regulation of RIG-I signaling pathway (GO:0039535)3.19899672
106cGMP biosynthetic process (GO:0006182)3.19565957
107modified amino acid transport (GO:0072337)3.16613208
108phosphate ion homeostasis (GO:0055062)3.15377412
109trivalent inorganic anion homeostasis (GO:0072506)3.15377412
110negative regulation of meiotic cell cycle (GO:0051447)3.14683648
111sphingomyelin metabolic process (GO:0006684)3.14340091
112ceramide catabolic process (GO:0046514)3.13638779
113O-glycan processing (GO:0016266)3.12207184
114thrombin receptor signaling pathway (GO:0070493)3.11159042
115positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.11116788
116negative regulation of leukocyte migration (GO:0002686)3.10621544
117vitamin biosynthetic process (GO:0009110)3.09840891
118sphingosine metabolic process (GO:0006670)3.07599731
119female gonad development (GO:0008585)3.06017166
120negative regulation of gene silencing (GO:0060969)3.04975076
121bicarbonate transport (GO:0015701)3.04377376
122mRNA modification (GO:0016556)3.04273130
123notochord development (GO:0030903)3.03206116
124sphingoid metabolic process (GO:0046519)3.02366200
125positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.99741663
126response to pheromone (GO:0019236)2.99697964
127regulation of germinal center formation (GO:0002634)2.99398598
128negative regulation of steroid metabolic process (GO:0045939)2.97233959
129cellular ketone body metabolic process (GO:0046950)2.96567843
130drinking behavior (GO:0042756)2.96519469
131regulation of penile erection (GO:0060405)2.96340434
132regulation of steroid hormone biosynthetic process (GO:0090030)2.96007999
133oocyte maturation (GO:0001556)2.90936233
134response to hepatocyte growth factor (GO:0035728)2.88481444
135cellular response to hepatocyte growth factor stimulus (GO:0035729)2.88481444
136detection of other organism (GO:0098543)2.87955722
137regulation of respiratory burst (GO:0060263)2.86542795
138positive regulation of lipoprotein lipase activity (GO:0051006)2.86392906
139positive regulation of triglyceride lipase activity (GO:0061365)2.86392906
140digestion (GO:0007586)2.86037444
141negative regulation of reproductive process (GO:2000242)2.85524074
142regulation of bile acid biosynthetic process (GO:0070857)2.84121820
143phosphatidylinositol acyl-chain remodeling (GO:0036149)2.83545673
144male meiosis (GO:0007140)2.82601739
145negative regulation of steroid biosynthetic process (GO:0010894)2.81126852
146positive regulation of guanylate cyclase activity (GO:0031284)2.79193770
147mitochondrial calcium ion homeostasis (GO:0051560)2.78311290
148receptor guanylyl cyclase signaling pathway (GO:0007168)2.78135159
149actin filament depolymerization (GO:0030042)2.77746720
150regulation of exit from mitosis (GO:0007096)2.74973040
151nucleotide transmembrane transport (GO:1901679)2.73485339
152chaperone-mediated protein transport (GO:0072321)2.73180600
153maintenance of gastrointestinal epithelium (GO:0030277)2.70292424
154replicative senescence (GO:0090399)2.69735122
155citrulline biosynthetic process (GO:0019240)2.68805885
156regulation of acrosome reaction (GO:0060046)2.65947819
157detection of bacterium (GO:0016045)2.65831452
158cGMP-mediated signaling (GO:0019934)2.63749982
159centriole assembly (GO:0098534)2.62183162
160bundle of His cell to Purkinje myocyte communication (GO:0086069)2.62084728
161positive regulation of megakaryocyte differentiation (GO:0045654)2.61955919
162regulation of glucocorticoid metabolic process (GO:0031943)2.60891357
163central nervous system myelination (GO:0022010)2.60750777
164axon ensheathment in central nervous system (GO:0032291)2.60750777
165phospholipid efflux (GO:0033700)2.58970673
166adenosine metabolic process (GO:0046085)2.58081080
167response to hydroperoxide (GO:0033194)2.57534660
168regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.56745649
169histamine secretion (GO:0001821)2.54850677
170snRNA transcription (GO:0009301)2.54617549
171regulation of meiosis I (GO:0060631)2.54310139
172myoblast migration (GO:0051451)2.50574455
173negative regulation of circadian rhythm (GO:0042754)2.50485090

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.38203509
2HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.85895375
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.71957481
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.53801710
5SMAD_19615063_ChIP-ChIP_OVARY_Human3.11538574
6GATA6_25053715_ChIP-Seq_YYC3_Human3.07477825
7CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.84278778
8KAP1_22055183_ChIP-Seq_ESCs_Mouse2.77804264
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.67392387
10TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.65674862
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.52390892
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.52138555
13EGR1_23403033_ChIP-Seq_LIVER_Mouse2.47320561
14VDR_22108803_ChIP-Seq_LS180_Human2.44782506
15GATA1_22025678_ChIP-Seq_K562_Human2.41967035
16RXR_22158963_ChIP-Seq_LIVER_Mouse2.38317541
17GBX2_23144817_ChIP-Seq_PC3_Human2.34675213
18PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.33067630
19GATA1_19941826_ChIP-Seq_K562_Human2.25773541
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.23737997
21LXR_22158963_ChIP-Seq_LIVER_Mouse2.21761708
22SUZ12_27294783_Chip-Seq_NPCs_Mouse2.13863726
23NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.12598833
24GATA2_19941826_ChIP-Seq_K562_Human2.12563324
25PPARA_22158963_ChIP-Seq_LIVER_Mouse2.11521839
26CDX2_19796622_ChIP-Seq_MESCs_Mouse2.11150603
27CDX2_20551321_ChIP-Seq_CACO-2_Human2.09539681
28NFE2_27457419_Chip-Seq_LIVER_Mouse2.08840509
29FOXO3_23340844_ChIP-Seq_DLD1_Human2.03444438
30BMI1_23680149_ChIP-Seq_NPCS_Mouse2.01747285
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.97910313
32RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.96526293
33IGF1R_20145208_ChIP-Seq_DFB_Human1.95901006
34GATA1_26923725_Chip-Seq_HPCs_Mouse1.94272556
35AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.91885943
36STAT3_18555785_Chip-Seq_ESCs_Mouse1.89096635
37RNF2_27304074_Chip-Seq_NSC_Mouse1.86276350
38EZH2_27294783_Chip-Seq_NPCs_Mouse1.85570244
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.80946871
40SUZ12_18555785_Chip-Seq_ESCs_Mouse1.79498907
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.76244351
42PCGF2_27294783_Chip-Seq_NPCs_Mouse1.75622899
43TAL1_26923725_Chip-Seq_HPCs_Mouse1.74039744
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.73640077
45NANOG_18555785_Chip-Seq_ESCs_Mouse1.73524700
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.71678701
47SOX2_18555785_Chip-Seq_ESCs_Mouse1.65341601
48FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.63503576
49P53_22387025_ChIP-Seq_ESCs_Mouse1.62362087
50FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.62183023
51STAT1_17558387_ChIP-Seq_HELA_Human1.62151970
52HNF4A_19822575_ChIP-Seq_HepG2_Human1.62038952
53CMYC_18555785_Chip-Seq_ESCs_Mouse1.61787204
54CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61152551
55E2F1_18555785_Chip-Seq_ESCs_Mouse1.60991247
56NMYC_18555785_Chip-Seq_ESCs_Mouse1.60604525
57BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.60568409
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59484603
59ZFX_18555785_Chip-Seq_ESCs_Mouse1.58189906
60CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.57311018
61OCT4_18555785_Chip-Seq_ESCs_Mouse1.56151713
62P300_18555785_Chip-Seq_ESCs_Mouse1.54818009
63ESRRB_18555785_Chip-Seq_ESCs_Mouse1.54080400
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53037566
65LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52834642
66PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.52828255
67BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.52583928
68KLF4_18555785_Chip-Seq_ESCs_Mouse1.51891769
69TP63_17297297_ChIP-ChIP_HaCaT_Human1.49350845
70AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.47268801
71EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.46130739
72CTCF_18555785_Chip-Seq_ESCs_Mouse1.45968320
73EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.43953037
74RUNX1_27457419_Chip-Seq_LIVER_Mouse1.43642089
75TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.41711224
76BCOR_27268052_Chip-Seq_Bcells_Human1.40067108
77FUS_26573619_Chip-Seq_HEK293_Human1.39981721
78FOXA1_25552417_ChIP-Seq_VCAP_Human1.39054737
79CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.38936362
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38532579
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38532579
82KDM2B_26808549_Chip-Seq_REH_Human1.37103242
83TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36782709
84FOXM1_26456572_ChIP-Seq_MCF-7_Human1.34844259
85KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.33705221
86SMAD1_18555785_Chip-Seq_ESCs_Mouse1.33672717
87GATA2_21666600_ChIP-Seq_HMVEC_Human1.33642555
88FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.33424721
89P300_19829295_ChIP-Seq_ESCs_Human1.30698315
90FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.30577361
91SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.29588303
92BCL6_27268052_Chip-Seq_Bcells_Human1.29585449
93SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28372974
94EZH2_22144423_ChIP-Seq_EOC_Human1.27564368
95GATA4_25053715_ChIP-Seq_YYC3_Human1.25763311
96TRIM28_21343339_ChIP-Seq_HEK293_Human1.24443596
97PIAS1_25552417_ChIP-Seq_VCAP_Human1.24320679
98MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.23900834
99CRX_20693478_ChIP-Seq_RETINA_Mouse1.22327787
100PU1_27457419_Chip-Seq_LIVER_Mouse1.22123179
101ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.21179123
102SOX2_27498859_Chip-Seq_STOMACH_Mouse1.20963866
103OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20543847
104CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19748013
105CEBPB_22108803_ChIP-Seq_LS180_Human1.19051128
106CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.19042947
107STAT1_20625510_ChIP-Seq_HELA_Human1.17575827
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.17474173
109LXR_22292898_ChIP-Seq_THP-1_Human1.17402225
110P53_22127205_ChIP-Seq_FIBROBLAST_Human1.17015401
111TP63_19390658_ChIP-ChIP_HaCaT_Human1.15951788
112PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.15921458
113MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15505659
114* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.14689582
115KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.13842416
116KLF5_25053715_ChIP-Seq_YYC3_Human1.13688858
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12264071
118HTT_18923047_ChIP-ChIP_STHdh_Human1.11667077
119* NCOR1_26117541_ChIP-Seq_K562_Human1.11436998
120SOX2_20726797_ChIP-Seq_SW620_Human1.10906482
121IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.10852186
122CLOCK_20551151_ChIP-Seq_293T_Human1.10521278
123EWS_26573619_Chip-Seq_HEK293_Human1.09339477
124CDX2_22108803_ChIP-Seq_LS180_Human1.09092917
125RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.08945993
126CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08775623
127PRDM14_20953172_ChIP-Seq_ESCs_Human1.07589428
128LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07262435
129LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06797385
130TET1_21451524_ChIP-Seq_MESCs_Mouse1.06647857
131STAT3_23295773_ChIP-Seq_U87_Human1.06136659
132RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04447932
133MYC_18940864_ChIP-ChIP_HL60_Human1.04147303
134ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04095967
135KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.03114564
136ESR1_15608294_ChIP-ChIP_MCF-7_Human1.02925840
137SA1_27219007_Chip-Seq_Bcells_Human1.02662161
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.02618751
139* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.02183768
140SMAD4_21799915_ChIP-Seq_A2780_Human1.01979578
141AR_21909140_ChIP-Seq_LNCAP_Human1.01862548
142ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01413772
143VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00170634
144SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.00021975
145TAF2_19829295_ChIP-Seq_ESCs_Human0.99802188
146ESR1_20079471_ChIP-ChIP_T-47D_Human0.98081044
147GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.98075521
148KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97738879
149KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97738879
150KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97738879
151FOXA1_21572438_ChIP-Seq_LNCaP_Human0.96742622
152* NANOG_20526341_ChIP-Seq_ESCs_Human0.95544165
153HNFA_21074721_ChIP-Seq_CACO-2_Human0.94778643
154STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.94756218
155PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94636063
156NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94490239
157AR_20517297_ChIP-Seq_VCAP_Human0.94365688
158TCF4_18268006_ChIP-ChIP_LS174T_Human0.94361828
159* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94214750
160PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.93893091
161TOP2B_26459242_ChIP-Seq_MCF-7_Human0.93122490
162FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.92826295
163KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92677792
164RACK7_27058665_Chip-Seq_MCF-7_Human0.90277382
165SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.89358898
166CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.89135480
167RAD21_21589869_ChIP-Seq_MESCs_Mouse0.88884313
168PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.88676741
169ZNF263_19887448_ChIP-Seq_K562_Human0.88557891
170GATA3_24758297_ChIP-Seq_MCF-7_Human0.88549469
171* PHF8_20622854_ChIP-Seq_HELA_Human0.88443198
172HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87549111
173ETS1_21867929_ChIP-Seq_TH2_Mouse0.86303195
174P300_27268052_Chip-Seq_Bcells_Human0.85985942
175GATA1_19941827_ChIP-Seq_MEL_Mouse0.85493675
176SOX2_22085726_ChIP-Seq_NPCs_Mouse0.84508789
177RXR_22108803_ChIP-Seq_LS180_Human0.84131957

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition5.34818290
2MP0003718_maternal_effect5.04937594
3MP0005360_urolithiasis4.47655431
4MP0003950_abnormal_plasma_membrane3.60673290
5MP0005365_abnormal_bile_salt3.51126586
6MP0009379_abnormal_foot_pigmentation3.49247209
7MP0010234_abnormal_vibrissa_follicle3.42378430
8MP0004264_abnormal_extraembryonic_tissu3.29726375
9MP0001666_abnormal_nutrient_absorption3.13724613
10MP0009697_abnormal_copulation2.91438426
11MP0003183_abnormal_peptide_metabolism2.82801819
12MP0000462_abnormal_digestive_system2.78733120
13MP0003646_muscle_fatigue2.42790498
14MP0002102_abnormal_ear_morphology2.41580409
15MP0005646_abnormal_pituitary_gland2.30400731
16MP0003693_abnormal_embryo_hatching2.22012044
17MP0001986_abnormal_taste_sensitivity2.19637328
18MP0000490_abnormal_crypts_of2.17549419
19MP0003868_abnormal_feces_composition2.01753284
20MP0001188_hyperpigmentation1.99220350
21MP0002132_abnormal_respiratory_system1.98787219
22MP0000566_synostosis1.98637781
23MP0009840_abnormal_foam_cell1.97807721
24MP0008877_abnormal_DNA_methylation1.93727152
25MP0005395_other_phenotype1.88311214
26MP0005409_darkened_coat_color1.87752419
27MP0006292_abnormal_olfactory_placode1.86627108
28MP0004147_increased_porphyrin_level1.86460758
29MP0003941_abnormal_skin_development1.85410581
30MP0010329_abnormal_lipoprotein_level1.84149271
31MP0003315_abnormal_perineum_morphology1.80882384
32MP0004782_abnormal_surfactant_physiolog1.79098476
33MP0005381_digestive/alimentary_phenotyp1.78772194
34MP0001663_abnormal_digestive_system1.78618618
35MP0001119_abnormal_female_reproductive1.76429115
36MP0005332_abnormal_amino_acid1.76108261
37MP0000678_abnormal_parathyroid_gland1.74989504
38MP0001873_stomach_inflammation1.72532809
39MP0008875_abnormal_xenobiotic_pharmacok1.65488451
40MP0009643_abnormal_urine_homeostasis1.64292617
41MP0005310_abnormal_salivary_gland1.63633817
42MP0005636_abnormal_mineral_homeostasis1.61735766
43MP0010352_gastrointestinal_tract_polyps1.58058061
44MP0003787_abnormal_imprinting1.56464481
45MP0005408_hypopigmentation1.56003543
46MP0008004_abnormal_stomach_pH1.55444331
47MP0001905_abnormal_dopamine_level1.51437293
48MP0005377_hearing/vestibular/ear_phenot1.50847522
49MP0003878_abnormal_ear_physiology1.50847522
50MP0001664_abnormal_digestion1.50211889
51MP0003699_abnormal_female_reproductive1.49905595
52MP0002277_abnormal_respiratory_mucosa1.43808471
53MP0001485_abnormal_pinna_reflex1.42032482
54MP0008260_abnormal_autophagy1.41327970
55MP0001529_abnormal_vocalization1.40620929
56MP0001764_abnormal_homeostasis1.37418730
57MP0002249_abnormal_larynx_morphology1.35491083
58MP0003866_abnormal_defecation1.34853436
59MP0003806_abnormal_nucleotide_metabolis1.29638669
60MP0010155_abnormal_intestine_physiology1.24292134
61MP0000015_abnormal_ear_pigmentation1.18685355
62MP0004484_altered_response_of1.16780812
63MP0000653_abnormal_sex_gland1.16277535
64MP0000579_abnormal_nail_morphology1.15575615
65MP0000613_abnormal_salivary_gland1.12944281
66MP0002396_abnormal_hematopoietic_system1.12759255
67MP0004270_analgesia1.12064011
68MP0003937_abnormal_limbs/digits/tail_de1.11624854
69MP0000477_abnormal_intestine_morphology1.11212387
70MP0002136_abnormal_kidney_physiology1.11094334
71MP0002118_abnormal_lipid_homeostasis1.10238294
72MP0002163_abnormal_gland_morphology1.08438759
73MP0002210_abnormal_sex_determination1.08424889
74MP0004043_abnormal_pH_regulation1.06606525
75MP0005670_abnormal_white_adipose1.05942686
76MP0001929_abnormal_gametogenesis1.05337741
77MP0005551_abnormal_eye_electrophysiolog1.04646285
78MP0005084_abnormal_gallbladder_morpholo1.04060605
79MP0002139_abnormal_hepatobiliary_system1.03393985
80MP0003136_yellow_coat_color1.03172362
81MP0010386_abnormal_urinary_bladder1.01581596
82MP0002138_abnormal_hepatobiliary_system0.99601300
83MP0002796_impaired_skin_barrier0.97887918
84MP0000470_abnormal_stomach_morphology0.96983367
85MP0001346_abnormal_lacrimal_gland0.96005428
86MP0000609_abnormal_liver_physiology0.89680623
87MP0002638_abnormal_pupillary_reflex0.89476161
88MP0005501_abnormal_skin_physiology0.89272014
89MP0000538_abnormal_urinary_bladder0.88796045
90MP0001963_abnormal_hearing_physiology0.87401920
91MP0005535_abnormal_body_temperature0.86305562
92MP0004019_abnormal_vitamin_homeostasis0.86273896
93MP0005319_abnormal_enzyme/_coenzyme0.85510307
94MP0001756_abnormal_urination0.83578797
95MP0002822_catalepsy0.80829229
96MP0004742_abnormal_vestibular_system0.80574716
97MP0000026_abnormal_inner_ear0.77463837
98MP0009115_abnormal_fat_cell0.77301330
99MP0003879_abnormal_hair_cell0.76732137
100MP0005584_abnormal_enzyme/coenzyme_acti0.75742958
101MP0001501_abnormal_sleep_pattern0.74095063
102MP0005085_abnormal_gallbladder_physiolo0.74036923
103MP0003252_abnormal_bile_duct0.73246273
104MP0003121_genomic_imprinting0.71851389
105MP0002971_abnormal_brown_adipose0.67395915
106MP0002098_abnormal_vibrissa_morphology0.66533400
107MP0005379_endocrine/exocrine_gland_phen0.65281916
108MP0009642_abnormal_blood_homeostasis0.64990422
109MP0006138_congestive_heart_failure0.64320843
110MP0008872_abnormal_physiological_respon0.62754558
111MP0009333_abnormal_splenocyte_physiolog0.62127838
112MP0002876_abnormal_thyroid_physiology0.61482379
113MP0005171_absent_coat_pigmentation0.61410067
114MP0001881_abnormal_mammary_gland0.61291765
115MP0002653_abnormal_ependyma_morphology0.60296989
116MP0002161_abnormal_fertility/fecundity0.59792860
117MP0008058_abnormal_DNA_repair0.59416157
118MP0001765_abnormal_ion_homeostasis0.59113656
119MP0006072_abnormal_retinal_apoptosis0.58892485
120MP0001502_abnormal_circadian_rhythm0.58300127
121MP0003300_gastrointestinal_ulcer0.57441627
122MP0004957_abnormal_blastocyst_morpholog0.56515451
123MP0003953_abnormal_hormone_level0.56397538
124MP0001145_abnormal_male_reproductive0.56367249
125MP0000230_abnormal_systemic_arterial0.55922942
126MP0000639_abnormal_adrenal_gland0.55254235
127MP0008995_early_reproductive_senescence0.54963146
128MP0001845_abnormal_inflammatory_respons0.54715434
129MP0000465_gastrointestinal_hemorrhage0.53974982
130MP0003191_abnormal_cellular_cholesterol0.52842775
131MP0008469_abnormal_protein_level0.52166115
132MP0005410_abnormal_fertilization0.52007233
133MP0005166_decreased_susceptibility_to0.51771180
134MP0008775_abnormal_heart_ventricle0.51694538
135MP0005448_abnormal_energy_balance0.51529644
136MP0005647_abnormal_sex_gland0.51126258
137MP0000762_abnormal_tongue_morphology0.49889041
138MP0005253_abnormal_eye_physiology0.49754830
139MP0003890_abnormal_embryonic-extraembry0.48878317
140MP0000372_irregular_coat_pigmentation0.48529454
141MP0005334_abnormal_fat_pad0.46598426
142MP0001730_embryonic_growth_arrest0.45355453
143MP0005666_abnormal_adipose_tissue0.44959086
144MP0010678_abnormal_skin_adnexa0.43522559
145MP0002078_abnormal_glucose_homeostasis0.43454391
146MP0010307_abnormal_tumor_latency0.42347504
147MP0000537_abnormal_urethra_morphology0.42301863
148MP0008789_abnormal_olfactory_epithelium0.40603143
149MP0009785_altered_susceptibility_to0.36629280
150MP0000427_abnormal_hair_cycle0.34510470
151MP0005174_abnormal_tail_pigmentation0.34034286
152MP0000377_abnormal_hair_follicle0.33427317
153MP0002069_abnormal_eating/drinking_beha0.31115526
154MP0001216_abnormal_epidermal_layer0.30835583
155MP0004947_skin_inflammation0.29894894
156MP0005376_homeostasis/metabolism_phenot0.29652305

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)4.93479370
2Hyperactive renin-angiotensin system (HP:0000841)4.91108656
3Congenital sensorineural hearing impairment (HP:0008527)4.15804315
4Abnormality of vitamin metabolism (HP:0100508)4.05140564
5Confusion (HP:0001289)3.99587869
6Nausea (HP:0002018)3.95252131
7Male infertility (HP:0003251)3.88792503
8Flat capital femoral epiphysis (HP:0003370)3.64189658
9Congenital stationary night blindness (HP:0007642)3.59322825
10Chromosomal breakage induced by crosslinking agents (HP:0003221)3.56796937
11Chronic diarrhea (HP:0002028)3.47211233
12Abnormality of renin-angiotensin system (HP:0000847)3.43249178
13Chromsome breakage (HP:0040012)3.41192909
14Prostate neoplasm (HP:0100787)3.41069548
15Hyperglycinuria (HP:0003108)3.34824651
16Thin bony cortex (HP:0002753)3.28684426
17Alkalosis (HP:0001948)3.26944318
18Megaloblastic anemia (HP:0001889)3.21795651
19Conjugated hyperbilirubinemia (HP:0002908)3.21590933
20Nephrolithiasis (HP:0000787)3.16165162
21Pigmentary retinal degeneration (HP:0001146)3.15187679
22Acanthocytosis (HP:0001927)3.07718369
23Abnormality of monocarboxylic acid metabolism (HP:0010996)3.06618108
24Posterior subcapsular cataract (HP:0007787)3.05507304
25Abnormality of aspartate family amino acid metabolism (HP:0010899)2.94836442
26Abnormality of glycine metabolism (HP:0010895)2.93036242
27Abnormality of serine family amino acid metabolism (HP:0010894)2.93036242
28Steatorrhea (HP:0002570)2.92434277
29Pustule (HP:0200039)2.89732786
30Increased purine levels (HP:0004368)2.89105627
31Hyperuricemia (HP:0002149)2.89105627
32Hypophosphatemia (HP:0002148)2.88849211
33Cupped ribs (HP:0000887)2.88573891
34Poikilocytosis (HP:0004447)2.84386094
35Abnormal urine phosphate concentration (HP:0012599)2.84239319
36Abdominal distention (HP:0003270)2.82881625
37Xanthomatosis (HP:0000991)2.81030652
38Hyperammonemia (HP:0001987)2.79278693
39Wide cranial sutures (HP:0010537)2.75644197
40Cheilitis (HP:0100825)2.71887033
41Malnutrition (HP:0004395)2.71334425
42Irregular epiphyses (HP:0010582)2.65738757
43Nonprogressive disorder (HP:0003680)2.63566391
44Hypergonadotropic hypogonadism (HP:0000815)2.63248856
45Adrenal hypoplasia (HP:0000835)2.63084973
46Hypophosphatemic rickets (HP:0004912)2.62982994
47Abnormality of sulfur amino acid metabolism (HP:0004339)2.53949109
48Abnormality of purine metabolism (HP:0004352)2.53590480
49Enlarged epiphyses (HP:0010580)2.49734852
50Right ventricular cardiomyopathy (HP:0011663)2.49201968
51Patchy hypopigmentation of hair (HP:0011365)2.46754564
52Cholecystitis (HP:0001082)2.46631043
53Abnormal gallbladder physiology (HP:0012438)2.46631043
54Parakeratosis (HP:0001036)2.46522327
55Autoimmune thrombocytopenia (HP:0001973)2.46361600
56Hypoplasia of the fovea (HP:0007750)2.44395948
57Aplasia/Hypoplasia of the fovea (HP:0008060)2.44395948
58Subcapsular cataract (HP:0000523)2.44254831
59Hypotension (HP:0002615)2.43644442
60White forelock (HP:0002211)2.42349318
61Hyperparathyroidism (HP:0000843)2.42263639
62Impulsivity (HP:0100710)2.39780403
63Hyperphosphaturia (HP:0003109)2.34782823
64Abnormality of nucleobase metabolism (HP:0010932)2.34778441
65Focal segmental glomerulosclerosis (HP:0000097)2.34380518
66Abnormality of glutamine family amino acid metabolism (HP:0010902)2.34319088
67Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.31831607
68Potter facies (HP:0002009)2.31749571
69Facial shape deformation (HP:0011334)2.31749571
70Abnormality of the preputium (HP:0100587)2.31699217
71Abnormality of the fovea (HP:0000493)2.31242454
72Hyperaldosteronism (HP:0000859)2.30283934
73Hemorrhage of the eye (HP:0011885)2.28567196
74Renal cortical cysts (HP:0000803)2.27166343
75Hypolipoproteinemia (HP:0010981)2.25804983
76Intrahepatic cholestasis (HP:0001406)2.24391591
77Stomach cancer (HP:0012126)2.24146114
78Abnormality of urine glucose concentration (HP:0011016)2.23954395
79Glycosuria (HP:0003076)2.23954395
80Dicarboxylic aciduria (HP:0003215)2.23305915
81Abnormality of dicarboxylic acid metabolism (HP:0010995)2.23305915
82Systemic lupus erythematosus (HP:0002725)2.23271121
83Cortical dysplasia (HP:0002539)2.23121620
84Metabolic acidosis (HP:0001942)2.22494607
85Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.21325161
86Severe combined immunodeficiency (HP:0004430)2.20738014
87Absent septum pellucidum (HP:0001331)2.18342410
88Abnormality of magnesium homeostasis (HP:0004921)2.17680370
89Combined immunodeficiency (HP:0005387)2.17677873
90Optic neuritis (HP:0100653)2.17097231
91Retrobulbar optic neuritis (HP:0100654)2.17097231
92Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.16028869
93Dehydration (HP:0001944)2.15949355
94Ectropion (HP:0000656)2.15848139
95Duplicated collecting system (HP:0000081)2.15413602
96Pili torti (HP:0003777)2.15215342
97Abnormality of the femoral head (HP:0003368)2.14222183
98Abnormal tarsal ossification (HP:0008369)2.14170953
99Widely patent fontanelles and sutures (HP:0004492)2.12319568
100Abnormality of the epiphysis of the femoral head (HP:0010574)2.12171066
101Hyponatremia (HP:0002902)2.11587675
102Abnormality of incisor morphology (HP:0011063)2.08979084
103Abnormality of the vitamin B12 metabolism (HP:0004341)2.08467704
104Villous atrophy (HP:0011473)2.07613217
105Abnormality of small intestinal villus morphology (HP:0011472)2.07613217
106Short femoral neck (HP:0100864)2.06828394
107Abnormality of the phalanges of the hallux (HP:0010057)2.06212865
108Generalized aminoaciduria (HP:0002909)2.05742425
109Decreased circulating renin level (HP:0003351)2.05166019
110Gout (HP:0001997)2.03866112
111Fat malabsorption (HP:0002630)2.03720769
112Cerebral palsy (HP:0100021)2.03200847
113Abnormality of the renal collecting system (HP:0004742)2.02198801
114Palpitations (HP:0001962)2.00861667
115Type 2 muscle fiber atrophy (HP:0003554)2.00852577
116Tetany (HP:0001281)2.00184945
117Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.99471900
118Abnormality of femoral epiphyses (HP:0006499)1.99471900
119Renal tubular dysfunction (HP:0000124)1.99178880
120Abnormality of the costochondral junction (HP:0000919)1.97561419
121Alopecia of scalp (HP:0002293)1.97522544
122Pulmonary fibrosis (HP:0002206)1.95745909
123Ventricular fibrillation (HP:0001663)1.95202326
124Degeneration of the lateral corticospinal tracts (HP:0002314)1.94849987
125Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.94849987
126Rickets (HP:0002748)1.94479357
127Abnormality of pyrimidine metabolism (HP:0004353)1.93733991
128Fetal akinesia sequence (HP:0001989)1.92725740
129Abnormality of chloride homeostasis (HP:0011422)1.91970723
130Papillary thyroid carcinoma (HP:0002895)1.91735272
131Premature ovarian failure (HP:0008209)1.91462773
132Abnormal biliary tract morphology (HP:0012440)1.90891158
133Delayed epiphyseal ossification (HP:0002663)1.90729755
134Renal tubular acidosis (HP:0001947)1.90655505
135Abnormality of vitamin B metabolism (HP:0004340)1.89880908
136Epidermoid cyst (HP:0200040)1.89392123
137Thyroiditis (HP:0100646)1.87305239
138Metabolic alkalosis (HP:0200114)1.87281762
139Hypocalcemia (HP:0002901)1.85998693
140Hypoplastic iliac wings (HP:0002866)1.85371716
141Hypobetalipoproteinemia (HP:0003563)1.84903918
142Osteomalacia (HP:0002749)1.84115971
143Gastrointestinal dysmotility (HP:0002579)1.83110158
144Hypokalemia (HP:0002900)1.82996864
145Abnormality of alkaline phosphatase activity (HP:0004379)1.82464381
146Hydroxyprolinuria (HP:0003080)1.81465304
147Abnormality of proline metabolism (HP:0010907)1.81465304
148Clubbing of toes (HP:0100760)1.80298881
149Breast hypoplasia (HP:0003187)1.78627160
150Abnormality of the prostate (HP:0008775)1.76275157
151Abnormality of placental membranes (HP:0011409)1.75400295
152Amniotic constriction ring (HP:0009775)1.75400295
153Aplasia/Hypoplasia involving the musculature (HP:0001460)1.75156392
154Abnormality of B cell number (HP:0010975)1.74915007
155B lymphocytopenia (HP:0010976)1.74915007
156Clitoromegaly (HP:0000057)1.74182132
157Aplasia/hypoplasia of the femur (HP:0005613)1.74177083
158Abnormality of the septum pellucidum (HP:0007375)1.73350892
159Hyperphosphatemia (HP:0002905)1.72306540
160Proximal tubulopathy (HP:0000114)1.72118542
161Abnormality of the clitoris (HP:0000056)1.68631311
162Flat acetabular roof (HP:0003180)1.68507268
163Aplasia cutis congenita (HP:0001057)1.67725349
164Autoimmune hemolytic anemia (HP:0001890)1.67606460
165Barrel-shaped chest (HP:0001552)1.66587756
166Anomalous pulmonary venous return (HP:0010772)1.65404570
167Symphalangism affecting the phalanges of the hand (HP:0009773)1.65379248
168Aplasia of the musculature (HP:0100854)1.64829583
169Insulin-resistant diabetes mellitus (HP:0000831)1.64240654
170Metaphyseal irregularity (HP:0003025)1.64045999

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.60988974
2LATS14.02921188
3TAOK33.69741643
4MUSK3.43964193
5FRK3.23449164
6ERN13.13099490
7MAP3K63.10709753
8PLK42.77374234
9RIPK12.74671546
10MAP3K102.70377567
11MET2.67788291
12ERBB42.59040458
13MOS2.58139822
14TTK2.54747537
15BMPR22.52219080
16STK38L2.41840114
17NUAK12.34212016
18CDK82.08374560
19TESK22.07374861
20BRAF2.06938799
21PRKG22.04913212
22MAP3K91.94460591
23MAPKAPK51.85476819
24CASK1.78733931
25RIPK41.76798909
26MAP3K21.72769472
27MST41.69911882
28AKT31.67336906
29OXSR11.63617749
30STK101.62924720
31MAP2K21.48839018
32CHEK21.46086426
33PBK1.45875350
34CDK31.44909855
35STK31.40096138
36STK241.36719138
37STK391.35511538
38PDK21.35362723
39PTK61.29893072
40BMPR1B1.24849970
41PIM11.24810902
42MAP3K11.18766924
43DYRK21.15397289
44LATS21.13392536
45INSRR1.12993642
46ADRBK21.11824768
47EIF2AK21.10185952
48PIK3CA1.08313384
49SGK4941.04247909
50SGK2231.04247909
51KSR11.04040862
52GRK11.02248071
53EPHB10.98128086
54KSR20.97991422
55MAP3K120.96081148
56LMTK20.94567550
57RAF10.91036559
58GRK60.90702277
59MST1R0.90415713
60CDK190.88145894
61MAP3K80.87737397
62MAP2K60.87717125
63NLK0.86090082
64EPHA40.83836697
65MYLK0.83497623
66TNIK0.83129394
67MAPK130.83129209
68PIK3CG0.82522728
69ERBB20.80306084
70VRK10.78356602
71CDK90.77216691
72TRPM70.76990047
73GRK70.76124124
74NEK60.75310790
75TYK20.74029476
76MAP3K130.73921902
77EPHA30.72956773
78YES10.72836360
79PRKAA20.69893507
80PRPF4B0.68813352
81PDPK10.68454306
82CCNB10.67791522
83PRKACG0.67559049
84MELK0.64552539
85NEK20.64001056
86BCR0.63990172
87OBSCN0.63614826
88NME10.62786786
89FGFR40.61172961
90MAP2K70.60894216
91MAPKAPK30.59354186
92ZAK0.58299091
93PTK20.57812841
94RET0.57681117
95PINK10.57121816
96CAMK2A0.57012219
97AURKB0.56988445
98PRKCA0.55746081
99MAP3K140.53205111
100PRKCZ0.52023390
101PDK10.49590061
102EEF2K0.49044787
103BMX0.47626620
104TXK0.45976616
105MATK0.45666203
106MAPK110.45474187
107JAK30.42285159
108DMPK0.41387094
109PLK10.41081466
110SGK20.40773432
111EIF2AK30.40551844
112TAOK10.40119045
113CAMK2D0.39006783
114TEC0.38985975
115PRKD30.38537565
116ABL10.38387389
117MKNK10.38002337
118NEK10.37975976
119CSNK1G10.37286758
120PAK10.36015720
121CAMK2G0.35949346
122PRKG10.35280550
123CDK70.34189253
124PRKAA10.33993479
125PRKCI0.33742995
126SIK30.33348010
127ARAF0.33224544
128CLK10.33082834
129EPHA20.33076297
130IKBKE0.33041481
131MAPK70.33033586
132EPHB20.32425185
133WNK40.32010655
134PKN10.31269178
135CDC42BPA0.31141787
136FGFR30.30510147
137DDR20.30051748
138PRKCE0.30012372
139CSNK1A1L0.29995285
140ZAP700.29284962
141CSNK1G30.29194815
142CSNK1A10.27915531
143PRKACA0.27290989
144JAK20.27174522
145SRC0.27096518
146MAP2K10.26131693
147MKNK20.25714792
148AURKA0.23889055
149LRRK20.23014161
150BRSK20.20321806
151PRKCD0.18003714
152CDK120.17934768
153ILK0.16916058
154FYN0.16574555
155MAPKAPK20.16541887
156MAP4K10.15394391
157SYK0.14444300

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004605.11262785
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.72365035
3Mineral absorption_Homo sapiens_hsa049783.65797150
4Fat digestion and absorption_Homo sapiens_hsa049753.57950170
5Renin-angiotensin system_Homo sapiens_hsa046143.16914211
6Vitamin digestion and absorption_Homo sapiens_hsa049773.13134216
7Sulfur metabolism_Homo sapiens_hsa009202.91907079
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.73576704
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.60981491
10Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.60684259
11Folate biosynthesis_Homo sapiens_hsa007902.58653659
12Linoleic acid metabolism_Homo sapiens_hsa005912.47996550
13Ovarian steroidogenesis_Homo sapiens_hsa049132.40915238
14Arginine biosynthesis_Homo sapiens_hsa002202.37285292
15Ether lipid metabolism_Homo sapiens_hsa005652.35796982
16Sphingolipid metabolism_Homo sapiens_hsa006002.33487005
17Drug metabolism - other enzymes_Homo sapiens_hsa009832.14765401
18Basal transcription factors_Homo sapiens_hsa030221.95280642
19Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.92250884
20Histidine metabolism_Homo sapiens_hsa003401.82912301
21PPAR signaling pathway_Homo sapiens_hsa033201.76712030
22Starch and sucrose metabolism_Homo sapiens_hsa005001.69336988
23Protein digestion and absorption_Homo sapiens_hsa049741.67165010
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.65991491
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.58084078
26Arachidonic acid metabolism_Homo sapiens_hsa005901.56497883
27Carbohydrate digestion and absorption_Homo sapiens_hsa049731.47138177
28Galactose metabolism_Homo sapiens_hsa000521.47005894
29RNA degradation_Homo sapiens_hsa030181.43651227
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.42209925
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41575456
32Phototransduction_Homo sapiens_hsa047441.40254842
33Vitamin B6 metabolism_Homo sapiens_hsa007501.34528266
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.27524937
35Steroid biosynthesis_Homo sapiens_hsa001001.26514049
36Fanconi anemia pathway_Homo sapiens_hsa034601.24631502
37Circadian rhythm_Homo sapiens_hsa047101.19342416
38Intestinal immune network for IgA production_Homo sapiens_hsa046721.16765409
39Cell cycle_Homo sapiens_hsa041101.16729620
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.16086258
41Steroid hormone biosynthesis_Homo sapiens_hsa001401.14021732
42Glutathione metabolism_Homo sapiens_hsa004801.12067010
43Retinol metabolism_Homo sapiens_hsa008301.11025962
442-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.10860498
45Fatty acid degradation_Homo sapiens_hsa000711.10503090
46Caffeine metabolism_Homo sapiens_hsa002321.09795702
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.09251189
48Glycerophospholipid metabolism_Homo sapiens_hsa005641.05024868
49Arginine and proline metabolism_Homo sapiens_hsa003301.04441166
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00282667
51Fatty acid elongation_Homo sapiens_hsa000621.00202926
52Fructose and mannose metabolism_Homo sapiens_hsa000510.99984313
53Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98075060
54Tryptophan metabolism_Homo sapiens_hsa003800.96087049
55Homologous recombination_Homo sapiens_hsa034400.94252641
56Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.93738032
57Oxidative phosphorylation_Homo sapiens_hsa001900.87126717
58Glycerolipid metabolism_Homo sapiens_hsa005610.86140754
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83409784
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80328350
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77456324
62Phenylalanine metabolism_Homo sapiens_hsa003600.72689735
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.72570179
64Non-homologous end-joining_Homo sapiens_hsa034500.72231470
65Tight junction_Homo sapiens_hsa045300.69239504
66Bile secretion_Homo sapiens_hsa049760.68986140
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68675837
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67916745
69Chemical carcinogenesis_Homo sapiens_hsa052040.62844609
70Huntingtons disease_Homo sapiens_hsa050160.59482267
71Purine metabolism_Homo sapiens_hsa002300.58125017
72Fatty acid metabolism_Homo sapiens_hsa012120.58093808
73Nitrogen metabolism_Homo sapiens_hsa009100.58089671
74TGF-beta signaling pathway_Homo sapiens_hsa043500.54785163
75Hematopoietic cell lineage_Homo sapiens_hsa046400.53789949
76NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53568029
77Pyruvate metabolism_Homo sapiens_hsa006200.50781859
78Metabolic pathways_Homo sapiens_hsa011000.48913136
79GnRH signaling pathway_Homo sapiens_hsa049120.47450948
80Rheumatoid arthritis_Homo sapiens_hsa053230.45820150
81Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45529717
82Peroxisome_Homo sapiens_hsa041460.44254034
83beta-Alanine metabolism_Homo sapiens_hsa004100.43928719
84Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43735905
85Sulfur relay system_Homo sapiens_hsa041220.39621460
86Alzheimers disease_Homo sapiens_hsa050100.39295049
87Serotonergic synapse_Homo sapiens_hsa047260.39023632
88Long-term depression_Homo sapiens_hsa047300.38438905
89Tyrosine metabolism_Homo sapiens_hsa003500.37952969
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37557458
91Parkinsons disease_Homo sapiens_hsa050120.37143351
92Asthma_Homo sapiens_hsa053100.36291894
93Pentose phosphate pathway_Homo sapiens_hsa000300.36162161
94Other glycan degradation_Homo sapiens_hsa005110.34138077
95Propanoate metabolism_Homo sapiens_hsa006400.33378286
96Choline metabolism in cancer_Homo sapiens_hsa052310.33066403
97Carbon metabolism_Homo sapiens_hsa012000.32791547
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.32073464
99Biosynthesis of amino acids_Homo sapiens_hsa012300.30734214
100Butanoate metabolism_Homo sapiens_hsa006500.29452921
101Primary immunodeficiency_Homo sapiens_hsa053400.29194993
102Fatty acid biosynthesis_Homo sapiens_hsa000610.28947549
103Prolactin signaling pathway_Homo sapiens_hsa049170.28317955
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28041605
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27968772
106Inositol phosphate metabolism_Homo sapiens_hsa005620.26738213
107Salmonella infection_Homo sapiens_hsa051320.26627089
108Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26386288
109ABC transporters_Homo sapiens_hsa020100.25394404
110Dorso-ventral axis formation_Homo sapiens_hsa043200.25257674
111African trypanosomiasis_Homo sapiens_hsa051430.25163059
112Insulin resistance_Homo sapiens_hsa049310.24434382
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.23408221
114Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.23044398
115Pancreatic cancer_Homo sapiens_hsa052120.22807556
116Base excision repair_Homo sapiens_hsa034100.22178443
117Autoimmune thyroid disease_Homo sapiens_hsa053200.21919216
118Nucleotide excision repair_Homo sapiens_hsa034200.19810470
119Vascular smooth muscle contraction_Homo sapiens_hsa042700.19662015
120SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19240307
121Regulation of autophagy_Homo sapiens_hsa041400.18692629
122Thyroid hormone synthesis_Homo sapiens_hsa049180.17756555
123p53 signaling pathway_Homo sapiens_hsa041150.17366935
124Pancreatic secretion_Homo sapiens_hsa049720.16579195
125Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.15986879
126Renin secretion_Homo sapiens_hsa049240.15561817
127NF-kappa B signaling pathway_Homo sapiens_hsa040640.13951060
128Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.13774548
129Mismatch repair_Homo sapiens_hsa034300.13327629
130Thyroid cancer_Homo sapiens_hsa052160.12200429
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.11899941
132Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.10554239
133Cysteine and methionine metabolism_Homo sapiens_hsa002700.03660045
134Cocaine addiction_Homo sapiens_hsa050300.02076897
135Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.01868202
136Allograft rejection_Homo sapiens_hsa053300.01104391
137* Gap junction_Homo sapiens_hsa04540-0.0961209
138AMPK signaling pathway_Homo sapiens_hsa04152-0.0915922
139N-Glycan biosynthesis_Homo sapiens_hsa00510-0.0902517
140Phosphatidylinositol signaling system_Homo sapiens_hsa04070-0.0831680
141Graft-versus-host disease_Homo sapiens_hsa05332-0.0765059
142Amphetamine addiction_Homo sapiens_hsa05031-0.0477130
143Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142-0.0379337
144Glucagon signaling pathway_Homo sapiens_hsa04922-0.0227499
145Hepatitis C_Homo sapiens_hsa05160-0.0202197
146Insulin secretion_Homo sapiens_hsa04911-0.0123573
147Primary bile acid biosynthesis_Homo sapiens_hsa00120-0.0113795

Most similar genes based on co-expression Upload to Enrichr

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