TUBB2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleobase catabolic process (GO:0046113)8.08208165
2layer formation in cerebral cortex (GO:0021819)7.06421072
3cell migration in hindbrain (GO:0021535)6.74697602
4response to pheromone (GO:0019236)5.77101767
5central nervous system projection neuron axonogenesis (GO:0021952)5.67332764
6neuron cell-cell adhesion (GO:0007158)5.40286066
7axonal fasciculation (GO:0007413)5.40064590
8neuron recognition (GO:0008038)5.35247532
9dendrite morphogenesis (GO:0048813)5.32098638
10dendritic spine morphogenesis (GO:0060997)5.00560596
11negative regulation of microtubule polymerization (GO:0031115)4.78966813
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.64106423
13protein localization to synapse (GO:0035418)4.60069677
14axon extension (GO:0048675)4.51916908
15vocalization behavior (GO:0071625)4.39630159
16central nervous system neuron axonogenesis (GO:0021955)4.38789389
17locomotory exploration behavior (GO:0035641)4.38428371
18regulation of synapse structural plasticity (GO:0051823)4.25108059
19postsynaptic membrane organization (GO:0001941)4.22852935
20establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.21539376
21mitochondrion transport along microtubule (GO:0047497)4.21539376
22positive regulation of synapse maturation (GO:0090129)4.16327160
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.13733221
24establishment of mitochondrion localization (GO:0051654)4.06695454
25exploration behavior (GO:0035640)4.04399057
26clathrin coat assembly (GO:0048268)4.00393048
27cerebral cortex radially oriented cell migration (GO:0021799)3.97868126
28synaptic vesicle maturation (GO:0016188)3.97580812
29regulation of glutamate receptor signaling pathway (GO:1900449)3.95407274
30hippocampus development (GO:0021766)3.94300855
31neuron projection extension (GO:1990138)3.94217221
32positive regulation of axon extension (GO:0045773)3.90167338
33regulation of short-term neuronal synaptic plasticity (GO:0048172)3.83391683
34cerebellum development (GO:0021549)3.82897444
35behavioral response to nicotine (GO:0035095)3.81689900
36positive regulation of filopodium assembly (GO:0051491)3.79941473
37gamma-aminobutyric acid transport (GO:0015812)3.78862459
38regulation of axon extension (GO:0030516)3.76635291
39cerebellar Purkinje cell layer development (GO:0021680)3.72090398
40positive regulation of dendritic spine morphogenesis (GO:0061003)3.64443467
41negative regulation of catenin import into nucleus (GO:0035414)3.63679901
42establishment of nucleus localization (GO:0040023)3.62103738
43calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.59761731
44positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.59257420
45cerebral cortex neuron differentiation (GO:0021895)3.58261721
46* neuron migration (GO:0001764)3.53394954
47retinal ganglion cell axon guidance (GO:0031290)3.52862262
48negative regulation of axon extension (GO:0030517)3.51343310
49positive regulation of synapse assembly (GO:0051965)3.50127435
50generation of neurons (GO:0048699)3.48910168
51glial cell proliferation (GO:0014009)3.47611890
52response to auditory stimulus (GO:0010996)3.47462984
53regulation of extent of cell growth (GO:0061387)3.42172133
54transmission of nerve impulse (GO:0019226)3.39549748
55auditory behavior (GO:0031223)3.38388534
56neurofilament cytoskeleton organization (GO:0060052)3.37865201
57regulation of synaptic vesicle exocytosis (GO:2000300)3.37530915
58regulation of microtubule polymerization (GO:0031113)3.32950656
59synaptic vesicle exocytosis (GO:0016079)3.31731233
60negative regulation of axonogenesis (GO:0050771)3.31124584
61mechanosensory behavior (GO:0007638)3.28775140
62negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.22056060
63forebrain neuron differentiation (GO:0021879)3.22006359
64positive regulation of dendritic spine development (GO:0060999)3.21195876
65ionotropic glutamate receptor signaling pathway (GO:0035235)3.18637901
66regulation of dendritic spine morphogenesis (GO:0061001)3.17856433
67neuronal ion channel clustering (GO:0045161)3.16952335
68proline transport (GO:0015824)3.15415760
69semaphorin-plexin signaling pathway (GO:0071526)3.15114725
70neuron projection morphogenesis (GO:0048812)3.14452660
71nonmotile primary cilium assembly (GO:0035058)3.13147001
72regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11857040
73regulation of synapse maturation (GO:0090128)3.10784211
74axonogenesis (GO:0007409)3.08238785
75negative regulation of axon guidance (GO:1902668)3.07993122
76glutamate receptor signaling pathway (GO:0007215)3.07456987
77regulation of synapse organization (GO:0050807)3.07142423
78dopamine receptor signaling pathway (GO:0007212)3.06129386
79positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.05750800
80regulation of axon guidance (GO:1902667)3.03772874
81regulation of neuron migration (GO:2001222)3.02642510
82regulation of axonogenesis (GO:0050770)3.02319388
83positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.01450891
84negative regulation of oligodendrocyte differentiation (GO:0048715)2.99449790
85spinal cord development (GO:0021510)2.99063898
86positive regulation of mitochondrial fission (GO:0090141)2.98933696
87regulation of synapse assembly (GO:0051963)2.98892186
88dendrite development (GO:0016358)2.98140478
89positive regulation of axonogenesis (GO:0050772)2.97828083
90regulation of NFAT protein import into nucleus (GO:0051532)2.97192856
91cerebellar granule cell differentiation (GO:0021707)2.95956136
92synapse assembly (GO:0007416)2.95551908
93regulation of axon extension involved in axon guidance (GO:0048841)2.94949974
94negative regulation of axon extension involved in axon guidance (GO:0048843)2.94226122
95olfactory bulb development (GO:0021772)2.93830958
96neuromuscular synaptic transmission (GO:0007274)2.93740499
97neurotransmitter-gated ion channel clustering (GO:0072578)2.92126493
98regulation of filopodium assembly (GO:0051489)2.92087609
99regulation of cAMP-dependent protein kinase activity (GO:2000479)2.90645109
100neurotransmitter secretion (GO:0007269)2.90371926
101negative regulation of synaptic transmission, GABAergic (GO:0032229)2.89270352
102homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.89069423
103regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.88842713
104developmental cell growth (GO:0048588)2.87194561
105regulation of neuronal synaptic plasticity (GO:0048168)2.86950379
106adult walking behavior (GO:0007628)2.86698280
107neuron-neuron synaptic transmission (GO:0007270)2.85665472
108organelle transport along microtubule (GO:0072384)2.84730558
109peptidyl-arginine methylation (GO:0018216)2.84636202
110peptidyl-arginine N-methylation (GO:0035246)2.84636202
111glutamate secretion (GO:0014047)2.84484356
112presynaptic membrane organization (GO:0097090)2.84293131
113adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.83248135
114dendritic spine organization (GO:0097061)2.81653623
115synapse organization (GO:0050808)2.80724797
116presynaptic membrane assembly (GO:0097105)2.80368928
117regulation of synaptic vesicle transport (GO:1902803)2.79782067
118sequestering of actin monomers (GO:0042989)2.79328508
119startle response (GO:0001964)2.78916909
120neuronal action potential propagation (GO:0019227)2.78493515
121heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.77325636
122axon cargo transport (GO:0008088)2.77107933
123substrate-independent telencephalic tangential migration (GO:0021826)2.76726978
124substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.76726978
125synaptic transmission, glutamatergic (GO:0035249)2.76687874
126regulation of dendritic spine development (GO:0060998)2.73080788
127limb bud formation (GO:0060174)2.72826354
128synaptic vesicle endocytosis (GO:0048488)2.64899034
129cytoskeleton-dependent intracellular transport (GO:0030705)2.64500782
130regulation of respiratory system process (GO:0044065)2.64463420
131epithelial cell differentiation involved in kidney development (GO:0035850)2.63983935
132regulation of synaptic transmission, glutamatergic (GO:0051966)2.61399742
133regulation of development, heterochronic (GO:0040034)2.59976906
134axon extension involved in axon guidance (GO:0048846)2.59442861
135neuron projection extension involved in neuron projection guidance (GO:1902284)2.59442861
136ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.58933428
137nervous system development (GO:0007399)2.58280955
138regulation of feeding behavior (GO:0060259)2.56323632
139spinal cord association neuron differentiation (GO:0021527)2.56099279
140pyrimidine nucleobase catabolic process (GO:0006208)10.2995195

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.71903713
2* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.10950973
3EZH2_27304074_Chip-Seq_ESCs_Mouse3.10770123
4CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.98670016
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.95697191
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.69106791
7EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.60877618
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.60611474
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.60611474
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.58672750
11REST_21632747_ChIP-Seq_MESCs_Mouse2.56578833
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.54890027
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.54713604
14GBX2_23144817_ChIP-Seq_PC3_Human2.50642517
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.41420417
16SUZ12_27294783_Chip-Seq_ESCs_Mouse2.39891726
17RNF2_27304074_Chip-Seq_ESCs_Mouse2.36799902
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.36059972
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35980147
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23163218
21* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.21265534
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.20426496
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.16068788
24SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.15565960
25EED_16625203_ChIP-ChIP_MESCs_Mouse2.14676784
26REST_18959480_ChIP-ChIP_MESCs_Mouse2.12575534
27ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08709967
28MTF2_20144788_ChIP-Seq_MESCs_Mouse2.04690288
29RBPJ_22232070_ChIP-Seq_NCS_Mouse2.04082710
30RARB_27405468_Chip-Seq_BRAIN_Mouse1.89354562
31DROSHA_22980978_ChIP-Seq_HELA_Human1.87567818
32RING1B_27294783_Chip-Seq_NPCs_Mouse1.86320519
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.85319449
34ZNF274_21170338_ChIP-Seq_K562_Hela1.82016808
35RING1B_27294783_Chip-Seq_ESCs_Mouse1.80165801
36TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.79462224
37AR_21572438_ChIP-Seq_LNCaP_Human1.78176214
38STAT6_21828071_ChIP-Seq_BEAS2B_Human1.77622326
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.77116228
40* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.74439370
41* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.71492184
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.71138436
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.71069396
44* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.67306571
45KDM2B_26808549_Chip-Seq_K562_Human1.64374038
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.63613783
47ZFP281_27345836_Chip-Seq_ESCs_Mouse1.59997469
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.58966595
49ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.54796179
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54629899
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.54297705
52SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.50764193
53TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.49362439
54IGF1R_20145208_ChIP-Seq_DFB_Human1.44817551
55RNF2_27304074_Chip-Seq_NSC_Mouse1.44105177
56P300_19829295_ChIP-Seq_ESCs_Human1.43268116
57FUS_26573619_Chip-Seq_HEK293_Human1.42396148
58PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.41819284
59GATA1_26923725_Chip-Seq_HPCs_Mouse1.39790909
60* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35789226
61TP53_20018659_ChIP-ChIP_R1E_Mouse1.33834644
62RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.33139847
63DNAJC2_21179169_ChIP-ChIP_NT2_Human1.30534721
64IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27459679
65BMI1_23680149_ChIP-Seq_NPCS_Mouse1.25084705
66* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.24416589
67SOX2_16153702_ChIP-ChIP_HESCs_Human1.24229094
68SMAD4_21799915_ChIP-Seq_A2780_Human1.23667697
69* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23212991
70KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.23194346
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.22052586
72FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.19938834
73RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.18066908
74MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15364745
75EWS_26573619_Chip-Seq_HEK293_Human1.15026970
76KDM2B_26808549_Chip-Seq_SUP-B15_Human1.13655397
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.13001823
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11958973
79VDR_22108803_ChIP-Seq_LS180_Human1.11697841
80WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09996325
81IRF1_19129219_ChIP-ChIP_H3396_Human1.08769627
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08580740
83DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.08547327
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08029047
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08029047
86AR_19668381_ChIP-Seq_PC3_Human1.07298970
87* KDM2B_26808549_Chip-Seq_JURKAT_Human1.07252352
88STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.06604295
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03688161
90PIAS1_25552417_ChIP-Seq_VCAP_Human1.03682847
91CTCF_27219007_Chip-Seq_Bcells_Human1.02707522
92* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.02363258
93MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01004574
94AR_25329375_ChIP-Seq_VCAP_Human1.00813307
95ISL1_27105846_Chip-Seq_CPCs_Mouse0.99005853
96CBP_20019798_ChIP-Seq_JUKART_Human0.98821819
97IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.98821819
98SOX9_26525672_Chip-Seq_HEART_Mouse0.98606198
99GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98587900
100P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97723343
101SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96026626
102SMAD3_21741376_ChIP-Seq_EPCs_Human0.95964425
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.95928139
104LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95741615
105KDM2B_26808549_Chip-Seq_DND41_Human0.95529450
106ELK4_26923725_Chip-Seq_MESODERM_Mouse0.95418578
107TOP2B_26459242_ChIP-Seq_MCF-7_Human0.95096016
108ZNF263_19887448_ChIP-Seq_K562_Human0.94998490
109SMAD4_21741376_ChIP-Seq_HESCs_Human0.94663038
110CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94644052
111ARNT_22903824_ChIP-Seq_MCF-7_Human0.94542414
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94246955
113MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94233081
114STAT3_23295773_ChIP-Seq_U87_Human0.94161748
115AHR_22903824_ChIP-Seq_MCF-7_Human0.93222304
116SMAD3_21741376_ChIP-Seq_ESCs_Human0.92524533
117* SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92071356
118* RUNX2_22187159_ChIP-Seq_PCA_Human0.91882742
119SOX3_22085726_ChIP-Seq_NPCs_Mouse0.90842121
120SALL1_21062744_ChIP-ChIP_HESCs_Human0.90412512
121GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.89229997
122POU5F1_16153702_ChIP-ChIP_HESCs_Human0.89147954
123POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.88926891
124CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.88563412
125NR3C1_23031785_ChIP-Seq_PC12_Mouse0.87898595
126* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87381117
127TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.85269491
128HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.84633535
129TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.82945742
130* TET1_21490601_ChIP-Seq_MESCs_Mouse0.82616842
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82068641
132TAF15_26573619_Chip-Seq_HEK293_Human0.81388314

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.84691554
2MP0000778_abnormal_nervous_system4.21106571
3MP0005423_abnormal_somatic_nervous3.64129112
4MP0004270_analgesia3.55690758
5MP0003880_abnormal_central_pattern3.42889167
6MP0002822_catalepsy3.06235706
7MP0003635_abnormal_synaptic_transmissio2.98630314
8MP0000569_abnormal_digit_pigmentation2.92150028
9MP0002063_abnormal_learning/memory/cond2.77441868
10MP0006276_abnormal_autonomic_nervous2.73171127
11MP0002184_abnormal_innervation2.50702552
12MP0000537_abnormal_urethra_morphology2.47118639
13MP0002734_abnormal_mechanical_nocicepti2.34444622
14MP0004858_abnormal_nervous_system2.25053564
15MP0002733_abnormal_thermal_nociception2.23977375
16MP0004811_abnormal_neuron_physiology2.16574093
17MP0000955_abnormal_spinal_cord2.12074732
18MP0001188_hyperpigmentation2.08488855
19MP0009780_abnormal_chondrocyte_physiolo2.00372566
20MP0001968_abnormal_touch/_nociception1.92208409
21MP0002557_abnormal_social/conspecific_i1.90811010
22MP0002572_abnormal_emotion/affect_behav1.89606156
23MP0009745_abnormal_behavioral_response1.89602563
24MP0002653_abnormal_ependyma_morphology1.85905248
25MP0002735_abnormal_chemical_nociception1.84743044
26MP0003861_abnormal_nervous_system1.82067480
27MP0004885_abnormal_endolymph1.78379658
28MP0001440_abnormal_grooming_behavior1.75077788
29MP0002152_abnormal_brain_morphology1.71380843
30MP0003122_maternal_imprinting1.71006844
31MP0002882_abnormal_neuron_morphology1.70087564
32MP0008789_abnormal_olfactory_epithelium1.69355945
33MP0005187_abnormal_penis_morphology1.64892407
34MP0001486_abnormal_startle_reflex1.64874605
35MP0002064_seizures1.63600746
36MP0001970_abnormal_pain_threshold1.63313472
37MP0005499_abnormal_olfactory_system1.63079490
38MP0005394_taste/olfaction_phenotype1.63079490
39MP0002102_abnormal_ear_morphology1.60836835
40MP0000631_abnormal_neuroendocrine_gland1.57505776
41MP0003329_amyloid_beta_deposits1.57359447
42MP0003119_abnormal_digestive_system1.53302683
43MP0004142_abnormal_muscle_tone1.50362305
44MP0005645_abnormal_hypothalamus_physiol1.50183065
45MP0001984_abnormal_olfaction1.46767521
46MP0003136_yellow_coat_color1.46186046
47MP0001348_abnormal_lacrimal_gland1.41271491
48MP0002067_abnormal_sensory_capabilities1.40321172
49MP0006292_abnormal_olfactory_placode1.36069992
50MP0002751_abnormal_autonomic_nervous1.35936876
51MP0005386_behavior/neurological_phenoty1.32957891
52MP0004924_abnormal_behavior1.32957891
53MP0002736_abnormal_nociception_after1.27497635
54MP0003890_abnormal_embryonic-extraembry1.25687809
55MP0003121_genomic_imprinting1.21939307
56MP0002909_abnormal_adrenal_gland1.21884707
57MP0000566_synostosis1.21723394
58MP0002066_abnormal_motor_capabilities/c1.20709659
59MP0009046_muscle_twitch1.20604847
60MP0003787_abnormal_imprinting1.16758896
61MP0005248_abnormal_Harderian_gland1.15946975
62MP0003938_abnormal_ear_development1.13302164
63MP0004742_abnormal_vestibular_system1.12753829
64MP0002752_abnormal_somatic_nervous1.12497613
65MP0000534_abnormal_ureter_morphology1.11370442
66MP0002234_abnormal_pharynx_morphology1.11291377
67MP0002081_perinatal_lethality1.10740566
68MP0003315_abnormal_perineum_morphology1.04423937
69MP0001905_abnormal_dopamine_level1.03794461
70MP0003942_abnormal_urinary_system1.02488407
71MP0005253_abnormal_eye_physiology1.01939329
72MP0003385_abnormal_body_wall1.01164396
73MP0005551_abnormal_eye_electrophysiolog0.99348587
74MP0008877_abnormal_DNA_methylation0.98280846
75MP0002272_abnormal_nervous_system0.97617057
76MP0003634_abnormal_glial_cell0.96293236
77MP0001293_anophthalmia0.95064886
78MP0002282_abnormal_trachea_morphology0.94744551
79MP0000049_abnormal_middle_ear0.93659580
80MP0003137_abnormal_impulse_conducting0.93579483
81MP0003937_abnormal_limbs/digits/tail_de0.92347083
82MP0001502_abnormal_circadian_rhythm0.89869044
83MP0002638_abnormal_pupillary_reflex0.89272382
84MP0005195_abnormal_posterior_eye0.88921399
85MP0008569_lethality_at_weaning0.88129023
86MP0001299_abnormal_eye_distance/0.87388524
87MP0001529_abnormal_vocalization0.87032466
88MP0005076_abnormal_cell_differentiation0.86752189
89MP0001485_abnormal_pinna_reflex0.85972943
90MP0002116_abnormal_craniofacial_bone0.85597454
91MP0002069_abnormal_eating/drinking_beha0.84976760
92MP0001963_abnormal_hearing_physiology0.83657231
93MP0000026_abnormal_inner_ear0.82613714
94MP0001286_abnormal_eye_development0.82379369
95MP0003283_abnormal_digestive_organ0.81816441
96MP0002233_abnormal_nose_morphology0.81757848
97MP0003755_abnormal_palate_morphology0.81160563
98MP0008961_abnormal_basal_metabolism0.79710460
99MP0005391_vision/eye_phenotype0.79239013
100MP0003011_delayed_dark_adaptation0.78846555
101MP0000751_myopathy0.78753973
102MP0002697_abnormal_eye_size0.78037740
103MP0003123_paternal_imprinting0.76702565
104MP0001849_ear_inflammation0.76392257
105MP0003567_abnormal_fetal_cardiomyocyte0.75391734
106MP0004133_heterotaxia0.74858051
107MP0001177_atelectasis0.74834870
108MP0002938_white_spotting0.73335028
109MP0002229_neurodegeneration0.72649244
110MP0010770_preweaning_lethality0.72490368
111MP0002082_postnatal_lethality0.72490368
112MP0010030_abnormal_orbit_morphology0.71888890
113MP0009053_abnormal_anal_canal0.71761283
114MP0002249_abnormal_larynx_morphology0.71651720
115MP0010769_abnormal_survival0.70802123
116MP0003303_peritoneal_inflammation0.69927450
117MP0006072_abnormal_retinal_apoptosis0.68261646
118MP0001943_abnormal_respiration0.67671863
119MP0004233_abnormal_muscle_weight0.67220920
120MP0003879_abnormal_hair_cell0.66899890
121MP0010768_mortality/aging0.66495333
122MP0000462_abnormal_digestive_system0.66126977
123MP0003115_abnormal_respiratory_system0.66078154
124MP0003935_abnormal_craniofacial_develop0.65920212

Predicted human phenotypes

RankGene SetZ-score
1Amyotrophic lateral sclerosis (HP:0007354)4.45325012
2Myokymia (HP:0002411)3.88710113
3Mutism (HP:0002300)3.87657176
4Supranuclear gaze palsy (HP:0000605)3.78015824
5Limb dystonia (HP:0002451)3.72281830
6Polyphagia (HP:0002591)3.60793499
7Abnormality of the corticospinal tract (HP:0002492)3.35666342
8Gait imbalance (HP:0002141)3.33555635
9Hyperacusis (HP:0010780)3.19021220
10Lissencephaly (HP:0001339)3.15265627
11Aplasia/Hypoplasia of the brainstem (HP:0007362)3.14491064
12Hypoplasia of the brainstem (HP:0002365)3.14491064
13Ankle clonus (HP:0011448)3.14484812
14Akinesia (HP:0002304)2.99831325
15Short 4th metacarpal (HP:0010044)2.99065714
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.99065714
17Apathy (HP:0000741)2.98286432
18Megalencephaly (HP:0001355)2.97722786
19Insomnia (HP:0100785)2.95981579
20Elfin facies (HP:0004428)2.95325405
21Insidious onset (HP:0003587)2.95151270
22Termporal pattern (HP:0011008)2.95151270
23Inappropriate behavior (HP:0000719)2.91099279
24Hepatoblastoma (HP:0002884)2.85403439
25* Pachygyria (HP:0001302)2.78369534
26Focal seizures (HP:0007359)2.76910131
27Agitation (HP:0000713)2.75895519
28Retinal dysplasia (HP:0007973)2.74943535
29Diminished motivation (HP:0000745)2.72605667
30Congenital primary aphakia (HP:0007707)2.67920022
31Overriding aorta (HP:0002623)2.67217575
32Failure to thrive in infancy (HP:0001531)2.62009204
33Disinhibition (HP:0000734)2.61883134
34Visual hallucinations (HP:0002367)2.61829350
35Nephrogenic diabetes insipidus (HP:0009806)2.61059273
36Cerebral inclusion bodies (HP:0100314)2.60508891
37Atrophy/Degeneration involving motor neurons (HP:0007373)2.60462876
38Medial flaring of the eyebrow (HP:0010747)2.60342202
39Broad-based gait (HP:0002136)2.58296226
40Papilledema (HP:0001085)2.55805305
41Hyperventilation (HP:0002883)2.55509345
42Renovascular hypertension (HP:0100817)2.55235530
43Amblyopia (HP:0000646)2.53696972
44Shoulder girdle muscle weakness (HP:0003547)2.53212916
45Neurofibrillary tangles (HP:0002185)2.50210087
46Urinary urgency (HP:0000012)2.49911443
47Astrocytoma (HP:0009592)2.49738459
48Abnormality of the astrocytes (HP:0100707)2.49738459
49Sacral dimple (HP:0000960)2.48569792
50Morphological abnormality of the pyramidal tract (HP:0002062)2.47474463
51Vaginal atresia (HP:0000148)2.46318906
52Abnormality of the lower motor neuron (HP:0002366)2.45974048
53Epileptic encephalopathy (HP:0200134)2.45721197
54Genetic anticipation (HP:0003743)2.44267775
55Renal duplication (HP:0000075)2.44108364
56Genital tract atresia (HP:0001827)2.43692551
57Exotropia (HP:0000577)2.41391527
58Sleep apnea (HP:0010535)2.40058167
59Split foot (HP:0001839)2.39127956
60Obstructive sleep apnea (HP:0002870)2.37758063
61Abnormal eating behavior (HP:0100738)2.35035919
62Heterotopia (HP:0002282)2.34232941
63* Excessive salivation (HP:0003781)2.33992900
64* Drooling (HP:0002307)2.33992900
65Abnormality of the labia minora (HP:0012880)2.33012676
66Poor eye contact (HP:0000817)2.31366664
67Septo-optic dysplasia (HP:0100842)2.28902997
68Spastic tetraplegia (HP:0002510)2.27825931
69Progressive cerebellar ataxia (HP:0002073)2.26415861
70Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.25559912
71True hermaphroditism (HP:0010459)2.24679239
72Lymphangioma (HP:0100764)2.24248271
73Abnormality of the 4th metacarpal (HP:0010012)2.24027957
74* Specific learning disability (HP:0001328)2.23110612
75Atonic seizures (HP:0010819)2.18788926
76Hypsarrhythmia (HP:0002521)2.18638296
77Germ cell neoplasia (HP:0100728)2.18384269
78Megalocornea (HP:0000485)2.17234984
79Focal motor seizures (HP:0011153)2.16404353
80EEG with generalized epileptiform discharges (HP:0011198)2.15502277
81Optic nerve hypoplasia (HP:0000609)2.13911467
82Pointed chin (HP:0000307)2.13867579
83Febrile seizures (HP:0002373)2.13369759
84Absent speech (HP:0001344)2.11235938
85Morphological abnormality of the middle ear (HP:0008609)2.09903277
86Poor suck (HP:0002033)2.09291460
87Aqueductal stenosis (HP:0002410)2.09118253
88Spastic gait (HP:0002064)2.08814571
89Impaired social interactions (HP:0000735)2.08293870
90Abnormal social behavior (HP:0012433)2.08293870
91Urinary bladder sphincter dysfunction (HP:0002839)2.08022951
92Sporadic (HP:0003745)2.07228061
93Large eyes (HP:0001090)2.06389355
94Flat cornea (HP:0007720)2.06122883
95Epileptiform EEG discharges (HP:0011182)2.05750453
96Abnormality of the diencephalon (HP:0010662)2.05728886
97High anterior hairline (HP:0009890)2.05140386
98Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.05071263
99Degeneration of the lateral corticospinal tracts (HP:0002314)2.05071263
100* Hypoplasia of the corpus callosum (HP:0002079)2.03635040
101Peripheral hypomyelination (HP:0007182)2.02527881
102Impaired vibration sensation in the lower limbs (HP:0002166)2.02064783
103Pancreatic fibrosis (HP:0100732)2.01515138
104Generalized tonic-clonic seizures (HP:0002069)2.00265728
105Poor coordination (HP:0002370)1.99814533
106Progressive inability to walk (HP:0002505)1.99512156
107Ulnar claw (HP:0001178)1.98730899
108Esotropia (HP:0000565)1.98585657
109Nephronophthisis (HP:0000090)1.97695789
110Broad foot (HP:0001769)1.96651124
111Torticollis (HP:0000473)1.95470098
112Hyperthyroidism (HP:0000836)1.95255328
113Shallow orbits (HP:0000586)1.94468581
114Renal hypoplasia (HP:0000089)1.91254456
115Subacute progressive viral hepatitis (HP:0006572)1.89440197
116Lower limb muscle weakness (HP:0007340)1.87252115
117Pancreatic cysts (HP:0001737)1.86538057
118Open mouth (HP:0000194)1.86298943
119Anencephaly (HP:0002323)1.85255249
120Anophthalmia (HP:0000528)1.85091095
121Micropenis (HP:0000054)1.84932280
122Oligodactyly (hands) (HP:0001180)1.84890216
123Neoplasm of the heart (HP:0100544)1.84615488
124Ependymoma (HP:0002888)1.84414041
125Macroorchidism (HP:0000053)1.84204140
126Intestinal atresia (HP:0011100)1.83182685
127Inability to walk (HP:0002540)1.82612831
128Stereotypic behavior (HP:0000733)1.82450462
129Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.82355751
130Autism (HP:0000717)1.81024640
131Pelvic girdle muscle weakness (HP:0003749)1.80881869
132Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.80417216
133Abnormality of midbrain morphology (HP:0002418)1.79614283
134Molar tooth sign on MRI (HP:0002419)1.79614283
135Precocious puberty (HP:0000826)1.79368535
136Narrow forehead (HP:0000341)1.79288704
137Action tremor (HP:0002345)1.78411787
138Postaxial hand polydactyly (HP:0001162)1.78051724
139* Cortical dysplasia (HP:0002539)1.77779029
140Dialeptic seizures (HP:0011146)1.77672402
141Cutaneous finger syndactyly (HP:0010554)1.77640473
142Obsessive-compulsive behavior (HP:0000722)1.76595157
143Fetal akinesia sequence (HP:0001989)1.76540260
144Wrist flexion contracture (HP:0001239)1.76019760
145Depression (HP:0000716)1.75748269
146Restlessness (HP:0000711)1.74802376
147Intellectual disability, moderate (HP:0002342)1.73544952
148Abnormal hair whorl (HP:0010721)1.72695368
149Labial hypoplasia (HP:0000066)1.71801113
150Cutaneous syndactyly (HP:0012725)1.71738997
151Generalized hypotonia (HP:0001290)1.71271359
152Oligodactyly (HP:0012165)1.69293329
153Hyperglycinemia (HP:0002154)1.69274577
154Abnormality of the musculature of the pelvis (HP:0001469)1.67823492

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK18.50716761
2DYRK23.32187159
3MAP3K92.80719020
4EPHB22.73478322
5MAPK132.40028132
6NTRK22.38688950
7ERBB32.38319566
8SIK22.36331695
9PHKG12.35624992
10PHKG22.35624992
11MINK12.27417504
12KSR12.25398304
13EPHA32.12708830
14MAP3K42.07001675
15WNK31.87566580
16LATS21.82008178
17TRIM281.81820817
18LIMK11.73412748
19MAP4K21.70573089
20PAK61.67035813
21ICK1.61279384
22MAP2K71.53396057
23TYRO31.51884853
24CSNK1G21.49481052
25NTRK31.44252368
26SRPK11.41462269
27DAPK21.36410360
28UHMK11.35700792
29CSNK1G31.33299864
30CDK51.22805892
31CSNK1A1L1.19065673
32PINK11.13062673
33SGK2231.11076432
34SGK4941.11076432
35BCR1.10912893
36MARK21.07117354
37TSSK61.05269534
38EPHA41.03171223
39RPS6KA41.03135882
40ERBB21.01119430
41CDK181.00339539
42CASK0.99189882
43TNIK0.98008126
44CDK140.96054333
45MAPK150.95967972
46CDK150.95842725
47EEF2K0.94606481
48MAP2K40.93304427
49TRIB30.93164026
50PNCK0.92652796
51RPS6KA20.91607455
52CAMKK10.91485135
53PKN10.91471706
54PRKCZ0.91312549
55DYRK1A0.89496292
56CSNK1G10.85915538
57CDK11A0.85694331
58RET0.80800474
59TESK10.80708035
60PAK30.79285355
61TAOK10.77505016
62FGFR20.76647552
63PKN20.75973433
64KSR20.72363444
65STK110.72259073
66MAP3K100.69964088
67PRKD30.69613554
68SIK30.68126811
69ALK0.67416461
70NTRK10.66596877
71ILK0.66133513
72SGK20.64714915
73PRKCE0.64365916
74TESK20.63826815
75CAMK2B0.63455113
76MAP3K60.62146635
77CAMK1G0.60917931
78PDGFRA0.59256378
79PRKCG0.58454301
80DYRK1B0.57944370
81MAPK90.57701154
82PLK20.56363940
83LMTK20.56355073
84FYN0.52041541
85BMPR1B0.51491497
86BCKDK0.50903444
87DAPK10.50852969
88RIPK10.50331512
89DDR20.47420419
90MKNK20.45464536
91WNK40.45151538
92DYRK30.43921018
93MAPK120.43636838
94ROCK10.42859460
95CDK30.41839873
96CSNK1D0.41315749
97CAMKK20.41028988
98PRKCI0.39981330
99PRKAA10.39434298
100CAMK40.39201882
101CDC42BPA0.37619133
102CSNK1A10.36036232
103VRK10.35936420
104EPHB10.35800044
105ADRBK20.35636141
106SCYL20.35127887
107MAPK80.34282927
108MAP3K20.33974667
109GRK50.33153367
110FER0.33143517
111MKNK10.33013989
112CAMK1D0.32764333
113RPS6KA50.32320716
114PRKACA0.31391774
115CDK190.31346932
116CSNK1E0.31322962
117FGR0.31302880
118PRKACB0.30770684
119RPS6KA10.30622463
120NEK10.28128176
121PRKDC0.26779113
122IRAK20.26682516
123MTOR0.26611099
124RPS6KA30.25955357
125CAMK2A0.25777123
126GSK3B0.25454792
127CAMK10.25273257
128STK160.25084361
129CAMK2G0.24726542
130MAP3K120.24377203
131MAPK100.24342041
132OXSR10.23828918
133PRKG10.23729395
134CCNB10.23499551
135PTK60.23350930

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043603.19390861
2Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.66624566
3Nicotine addiction_Homo sapiens_hsa050332.33805835
4Steroid biosynthesis_Homo sapiens_hsa001002.30629933
5Endometrial cancer_Homo sapiens_hsa052132.16393472
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.16056284
7Colorectal cancer_Homo sapiens_hsa052102.08087303
8Synaptic vesicle cycle_Homo sapiens_hsa047212.05172018
9Dopaminergic synapse_Homo sapiens_hsa047282.01166374
10Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.89947095
11Glutamatergic synapse_Homo sapiens_hsa047241.89514890
12Circadian entrainment_Homo sapiens_hsa047131.87285615
13GABAergic synapse_Homo sapiens_hsa047271.85887272
14Cholinergic synapse_Homo sapiens_hsa047251.80086823
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.78487236
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.72750093
17Phototransduction_Homo sapiens_hsa047441.69487430
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.68941217
19Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.63175282
20* Gap junction_Homo sapiens_hsa045401.62619712
21Olfactory transduction_Homo sapiens_hsa047401.56317176
22ErbB signaling pathway_Homo sapiens_hsa040121.55365036
23Basal cell carcinoma_Homo sapiens_hsa052171.53927669
24Morphine addiction_Homo sapiens_hsa050321.53736044
25Long-term potentiation_Homo sapiens_hsa047201.53011000
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.50733126
27Glioma_Homo sapiens_hsa052141.48516825
28Renal cell carcinoma_Homo sapiens_hsa052111.45864340
29Neurotrophin signaling pathway_Homo sapiens_hsa047221.41017598
30Cocaine addiction_Homo sapiens_hsa050301.40294522
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.40034542
32Hippo signaling pathway_Homo sapiens_hsa043901.37632966
33Viral myocarditis_Homo sapiens_hsa054161.37201652
34Estrogen signaling pathway_Homo sapiens_hsa049151.32605545
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.30843076
36Long-term depression_Homo sapiens_hsa047301.30059581
37Parkinsons disease_Homo sapiens_hsa050121.28571159
38Oxytocin signaling pathway_Homo sapiens_hsa049211.27998834
39Melanogenesis_Homo sapiens_hsa049161.24292404
40Amphetamine addiction_Homo sapiens_hsa050311.23459725
41Type II diabetes mellitus_Homo sapiens_hsa049301.23395657
42Serotonergic synapse_Homo sapiens_hsa047261.23355925
43mTOR signaling pathway_Homo sapiens_hsa041501.22751173
44GnRH signaling pathway_Homo sapiens_hsa049121.21060625
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.21001768
46Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.19810557
47Oxidative phosphorylation_Homo sapiens_hsa001901.18620956
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.18211581
49Wnt signaling pathway_Homo sapiens_hsa043101.17820662
50VEGF signaling pathway_Homo sapiens_hsa043701.16016203
51Hedgehog signaling pathway_Homo sapiens_hsa043401.14788467
52Oocyte meiosis_Homo sapiens_hsa041141.11304375
53Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10335477
54Aldosterone synthesis and secretion_Homo sapiens_hsa049251.08486123
55Insulin secretion_Homo sapiens_hsa049111.07958270
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.07125684
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.06281159
58Renin secretion_Homo sapiens_hsa049241.05430285
59Collecting duct acid secretion_Homo sapiens_hsa049661.02691491
60Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.01088308
61Non-small cell lung cancer_Homo sapiens_hsa052230.99847900
62Choline metabolism in cancer_Homo sapiens_hsa052310.97700789
63Alcoholism_Homo sapiens_hsa050340.97691656
64Chronic myeloid leukemia_Homo sapiens_hsa052200.97554488
65Protein export_Homo sapiens_hsa030600.97109325
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.96462183
67Taste transduction_Homo sapiens_hsa047420.93719584
68Notch signaling pathway_Homo sapiens_hsa043300.92900347
69Insulin signaling pathway_Homo sapiens_hsa049100.92595518
70Gastric acid secretion_Homo sapiens_hsa049710.92449030
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91119798
72Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91055073
73Salivary secretion_Homo sapiens_hsa049700.90921937
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.90595262
75Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88694443
76Vibrio cholerae infection_Homo sapiens_hsa051100.88067726
77Dorso-ventral axis formation_Homo sapiens_hsa043200.86890564
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86821916
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86203931
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.86026129
81Huntingtons disease_Homo sapiens_hsa050160.85549510
82Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.85308438
83Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.83131141
84MAPK signaling pathway_Homo sapiens_hsa040100.83033005
85Alzheimers disease_Homo sapiens_hsa050100.82706271
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81920709
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.81404533
88* Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81164098
89Pancreatic cancer_Homo sapiens_hsa052120.80725137
90Ras signaling pathway_Homo sapiens_hsa040140.79117593
91AMPK signaling pathway_Homo sapiens_hsa041520.79025595
92mRNA surveillance pathway_Homo sapiens_hsa030150.78717504
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.78013674
94MicroRNAs in cancer_Homo sapiens_hsa052060.76588760
95Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76553521
96Tight junction_Homo sapiens_hsa045300.76521471
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.75570056
98Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72229749
99Rap1 signaling pathway_Homo sapiens_hsa040150.72182864
100cAMP signaling pathway_Homo sapiens_hsa040240.69287036
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68648834
102Central carbon metabolism in cancer_Homo sapiens_hsa052300.68461691
103Endocytosis_Homo sapiens_hsa041440.67354332
104Basal transcription factors_Homo sapiens_hsa030220.66860736
105Prolactin signaling pathway_Homo sapiens_hsa049170.66684198
106cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64280596
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64178329
108Prion diseases_Homo sapiens_hsa050200.63906184
109Regulation of autophagy_Homo sapiens_hsa041400.62492224
110Ether lipid metabolism_Homo sapiens_hsa005650.62437522
111Dilated cardiomyopathy_Homo sapiens_hsa054140.61056428
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60630877
113Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.55648296
114Melanoma_Homo sapiens_hsa052180.55610978
115Calcium signaling pathway_Homo sapiens_hsa040200.54119719
116Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52213283
117Adherens junction_Homo sapiens_hsa045200.50025912
118Butanoate metabolism_Homo sapiens_hsa006500.49474397
119Proteoglycans in cancer_Homo sapiens_hsa052050.49454548
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48677872
121Pathways in cancer_Homo sapiens_hsa052000.48525035
122Cardiac muscle contraction_Homo sapiens_hsa042600.48362673
123Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47770225
124N-Glycan biosynthesis_Homo sapiens_hsa005100.47464438
125Circadian rhythm_Homo sapiens_hsa047100.45076329
126Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42400038
127RNA degradation_Homo sapiens_hsa030180.38566388
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37285435
129Propanoate metabolism_Homo sapiens_hsa006400.31485993
130Spliceosome_Homo sapiens_hsa030400.28449049
131Fatty acid metabolism_Homo sapiens_hsa012120.26247320
132Salmonella infection_Homo sapiens_hsa051320.25825240
133Biosynthesis of amino acids_Homo sapiens_hsa012300.25243468
134Peroxisome_Homo sapiens_hsa041460.24196210
135beta-Alanine metabolism_Homo sapiens_hsa004100.23018872

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »