Rank | Gene Set | Z-score |
---|---|---|
1 | motile cilium assembly (GO:0044458) | 5.87374128 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 4.82215813 |
3 | Golgi transport vesicle coating (GO:0048200) | 4.82215813 |
4 | protein localization to kinetochore (GO:0034501) | 4.72467157 |
5 | cilium movement (GO:0003341) | 4.49478840 |
6 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.48920471 |
7 | protein localization to chromosome, centromeric region (GO:0071459) | 4.46685399 |
8 | DNA unwinding involved in DNA replication (GO:0006268) | 4.42640093 |
9 | DNA replication initiation (GO:0006270) | 4.38961342 |
10 | mitotic metaphase plate congression (GO:0007080) | 4.30241426 |
11 | mitotic sister chromatid segregation (GO:0000070) | 4.28332701 |
12 | DNA strand elongation (GO:0022616) | 4.21020689 |
13 | mitotic nuclear envelope disassembly (GO:0007077) | 4.09104671 |
14 | mitotic chromosome condensation (GO:0007076) | 4.07517286 |
15 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.04406423 |
16 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.03135822 |
17 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.03135822 |
18 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.01580312 |
19 | proline biosynthetic process (GO:0006561) | 3.91314773 |
20 | nuclear envelope disassembly (GO:0051081) | 3.88571491 |
21 | membrane disassembly (GO:0030397) | 3.88571491 |
22 | formation of translation preinitiation complex (GO:0001731) | 3.83430301 |
23 | piRNA metabolic process (GO:0034587) | 3.82733198 |
24 | sister chromatid segregation (GO:0000819) | 3.80280402 |
25 | metaphase plate congression (GO:0051310) | 3.78422971 |
26 | left/right pattern formation (GO:0060972) | 3.78215626 |
27 | regulation of spindle organization (GO:0090224) | 3.75061004 |
28 | protein maturation by protein folding (GO:0022417) | 3.71586355 |
29 | chromatin remodeling at centromere (GO:0031055) | 3.70600609 |
30 | microtubule depolymerization (GO:0007019) | 3.69578022 |
31 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.67100388 |
32 | DNA replication checkpoint (GO:0000076) | 3.64857468 |
33 | establishment of apical/basal cell polarity (GO:0035089) | 3.61344242 |
34 | nucleobase biosynthetic process (GO:0046112) | 3.59858773 |
35 | DNA deamination (GO:0045006) | 3.58261823 |
36 | CENP-A containing nucleosome assembly (GO:0034080) | 3.57784188 |
37 | establishment of chromosome localization (GO:0051303) | 3.48480225 |
38 | epithelial cilium movement (GO:0003351) | 3.48157879 |
39 | histone exchange (GO:0043486) | 3.47892496 |
40 | establishment of integrated proviral latency (GO:0075713) | 3.47578219 |
41 | nuclear pore organization (GO:0006999) | 3.47347594 |
42 | telomere maintenance via recombination (GO:0000722) | 3.45958488 |
43 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.44996706 |
44 | maturation of SSU-rRNA (GO:0030490) | 3.43764167 |
45 | mitotic nuclear envelope reassembly (GO:0007084) | 3.43572670 |
46 | nuclear envelope reassembly (GO:0031468) | 3.43572670 |
47 | protein complex localization (GO:0031503) | 3.42398252 |
48 | mitotic recombination (GO:0006312) | 3.41828849 |
49 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.41791914 |
50 | regulation of translational termination (GO:0006449) | 3.41118406 |
51 | regulation of chromosome segregation (GO:0051983) | 3.40388925 |
52 | synaptonemal complex assembly (GO:0007130) | 3.36930109 |
53 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.36878406 |
54 | DNA replication-independent nucleosome organization (GO:0034724) | 3.36878406 |
55 | chromosome condensation (GO:0030261) | 3.36226895 |
56 | binding of sperm to zona pellucida (GO:0007339) | 3.35554124 |
57 | axonemal dynein complex assembly (GO:0070286) | 3.34352929 |
58 | positive regulation of chromosome segregation (GO:0051984) | 3.32473819 |
59 | purine nucleobase biosynthetic process (GO:0009113) | 3.31588574 |
60 | synaptonemal complex organization (GO:0070193) | 3.31116181 |
61 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.31110533 |
62 | protein retention in ER lumen (GO:0006621) | 3.30177534 |
63 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.29331976 |
64 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.25847050 |
65 | nuclear pore complex assembly (GO:0051292) | 3.24181052 |
66 | primary alcohol catabolic process (GO:0034310) | 3.22122826 |
67 | negative regulation of chromosome segregation (GO:0051985) | 3.20994866 |
68 | protein localization to chromosome (GO:0034502) | 3.20297190 |
69 | IMP biosynthetic process (GO:0006188) | 3.19169003 |
70 | ribosome assembly (GO:0042255) | 3.17867950 |
71 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.17602108 |
72 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.15355242 |
73 | negative regulation of sister chromatid segregation (GO:0033046) | 3.15355242 |
74 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.15355242 |
75 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.15355242 |
76 | ribosome biogenesis (GO:0042254) | 3.14665896 |
77 | telomere maintenance via telomere lengthening (GO:0010833) | 3.13415367 |
78 | chaperone-mediated protein complex assembly (GO:0051131) | 3.12309611 |
79 | desmosome organization (GO:0002934) | 3.12248790 |
80 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.10994135 |
81 | regulation of centrosome cycle (GO:0046605) | 3.09963127 |
82 | kinetochore organization (GO:0051383) | 3.08919678 |
83 | nuclear envelope organization (GO:0006998) | 3.08481794 |
84 | spindle checkpoint (GO:0031577) | 3.08129583 |
85 | mitotic spindle assembly checkpoint (GO:0007094) | 3.06306250 |
86 | spindle assembly checkpoint (GO:0071173) | 3.06143212 |
87 | regulation of histone H3-K9 methylation (GO:0051570) | 3.05222832 |
88 | translesion synthesis (GO:0019985) | 3.04864230 |
89 | translational elongation (GO:0006414) | 3.04708804 |
90 | viral transcription (GO:0019083) | 3.04426255 |
91 | regulation of mitotic spindle organization (GO:0060236) | 3.03295395 |
92 | translational termination (GO:0006415) | 3.02953427 |
93 | DNA packaging (GO:0006323) | 3.02858014 |
94 | male meiosis (GO:0007140) | 3.02290170 |
95 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.01230952 |
96 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.00437312 |
97 | ribosomal large subunit biogenesis (GO:0042273) | 3.00121523 |
98 | ribosomal small subunit assembly (GO:0000028) | 2.99707912 |
99 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.96987093 |
100 | pentose-phosphate shunt (GO:0006098) | 2.96378593 |
101 | translational initiation (GO:0006413) | 2.96299373 |
102 | chromatin assembly or disassembly (GO:0006333) | 2.94432764 |
103 | IMP metabolic process (GO:0046040) | 2.94159237 |
104 | sperm-egg recognition (GO:0035036) | 2.94038614 |
105 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.93975957 |
106 | postreplication repair (GO:0006301) | 2.93965235 |
107 | ventricular cardiac muscle cell development (GO:0055015) | 2.93763991 |
108 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.93657047 |
109 | mitotic spindle checkpoint (GO:0071174) | 2.93400339 |
110 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.92122525 |
111 | vitamin transmembrane transport (GO:0035461) | 2.91916282 |
112 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.91794829 |
113 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.91405040 |
114 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.91091903 |
115 | UTP biosynthetic process (GO:0006228) | 2.90570836 |
116 | meiotic nuclear division (GO:0007126) | 2.90314917 |
117 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.89723325 |
118 | DNA duplex unwinding (GO:0032508) | 2.89151903 |
119 | spliceosomal snRNP assembly (GO:0000387) | 2.88094835 |
120 | chromosome segregation (GO:0007059) | 2.87961801 |
121 | cellular protein complex localization (GO:0034629) | 2.87648523 |
122 | heterochromatin organization (GO:0070828) | 2.86641394 |
123 | DNA geometric change (GO:0032392) | 2.86407592 |
124 | establishment of viral latency (GO:0019043) | 2.85698214 |
125 | diterpenoid biosynthetic process (GO:0016102) | 2.83926598 |
126 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.83059803 |
127 | * mitotic cell cycle (GO:0000278) | 2.82657597 |
128 | protein K6-linked ubiquitination (GO:0085020) | 2.82641920 |
129 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.77257408 |
130 | DNA topological change (GO:0006265) | 2.75841823 |
131 | establishment of monopolar cell polarity (GO:0061162) | 2.72419143 |
132 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.72419143 |
133 | lung epithelium development (GO:0060428) | 2.69244823 |
134 | regulation of translational fidelity (GO:0006450) | 2.66970749 |
135 | glucose catabolic process (GO:0006007) | 2.66890918 |
136 | NADPH regeneration (GO:0006740) | 2.64757342 |
137 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.63399032 |
138 | proline metabolic process (GO:0006560) | 2.60529228 |
139 | mitotic cytokinesis (GO:0000281) | 2.60159071 |
140 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.59729753 |
141 | activation of Rac GTPase activity (GO:0032863) | 2.57241420 |
142 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.56337460 |
143 | DNA ligation (GO:0006266) | 2.55720693 |
144 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.54537001 |
145 | microtubule polymerization or depolymerization (GO:0031109) | 2.51798590 |
146 | regulation of microtubule depolymerization (GO:0031114) | 2.50254478 |
147 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.48868675 |
148 | epithelial cell-cell adhesion (GO:0090136) | 2.48815178 |
149 | negative regulation of microtubule depolymerization (GO:0007026) | 2.47716188 |
150 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.47593142 |
151 | GDP-mannose metabolic process (GO:0019673) | 2.46829064 |
152 | protein depolymerization (GO:0051261) | 2.44742894 |
153 | regulation of sister chromatid cohesion (GO:0007063) | 2.40323633 |
154 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.39180429 |
155 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.39074361 |
156 | glomerular epithelial cell development (GO:0072310) | 2.35052361 |
157 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.34520869 |
158 | spindle assembly involved in mitosis (GO:0090307) | 2.33922942 |
159 | maternal placenta development (GO:0001893) | 2.33302084 |
160 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.31670934 |
161 | adherens junction assembly (GO:0034333) | 2.29959619 |
162 | positive regulation of cytokinesis (GO:0032467) | 2.26813913 |
163 | mitochondrial fusion (GO:0008053) | 2.26353941 |
164 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.25807904 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.60068487 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.95337430 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.05006129 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.95013852 |
5 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.79160152 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.37837303 |
7 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.31489988 |
8 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.10925148 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.85627251 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.73045731 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.72201980 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.56130161 |
13 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.50443979 |
14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45966510 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.42143470 |
16 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.40452905 |
17 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.38128338 |
18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.30989284 |
19 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.30654319 |
20 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.26533435 |
21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.20039730 |
22 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.19641654 |
23 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.19363706 |
24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.92152014 |
25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.92111826 |
26 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.91319346 |
27 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.85111172 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.84570883 |
29 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.83073281 |
30 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.82016050 |
31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.80980394 |
32 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.78881039 |
33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.76761773 |
34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.76078293 |
35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.69528186 |
36 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.68856805 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.67976473 |
38 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.66465523 |
39 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.65764527 |
40 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.65556543 |
41 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.62510015 |
42 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.61813014 |
43 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.61809993 |
44 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.60192793 |
45 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.58294774 |
46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.57793694 |
47 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.57769486 |
48 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.54842578 |
49 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.51529975 |
50 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.50406966 |
51 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.49843988 |
52 | MYC_22102868_ChIP-Seq_BL_Human | 1.47181192 |
53 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.47166756 |
54 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.45708549 |
55 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.45146035 |
56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.44001996 |
57 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.43802932 |
58 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.42880766 |
59 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.42672360 |
60 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.42381907 |
61 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.40622154 |
62 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.39205049 |
63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38412914 |
64 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.34793702 |
65 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.34600920 |
66 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.33122417 |
67 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.32343787 |
68 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.31924845 |
69 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27441910 |
70 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.26270017 |
71 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.25953050 |
72 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.24469044 |
73 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22951473 |
74 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.22153243 |
75 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.21244648 |
76 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.18474887 |
77 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.18378586 |
78 | P68_20966046_ChIP-Seq_HELA_Human | 1.17368563 |
79 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.14395476 |
80 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.13280361 |
81 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.13279257 |
82 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.12315382 |
83 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.11721925 |
84 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.11329167 |
85 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.11304913 |
86 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.10590441 |
87 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.09557513 |
88 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.09526610 |
89 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.09220726 |
90 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09162955 |
91 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08510958 |
92 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.06004362 |
93 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.05530907 |
94 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.04425152 |
95 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.03709347 |
96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.03497422 |
97 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.03179126 |
98 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.02841421 |
99 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.02217753 |
100 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.01623636 |
101 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.01533235 |
102 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00828728 |
103 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.00381982 |
104 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.99072764 |
105 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.99044694 |
106 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.98711348 |
107 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.97907268 |
108 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.97230279 |
109 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.96678767 |
110 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.94701982 |
111 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.94594421 |
112 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.94386822 |
113 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.94321662 |
114 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.94249469 |
115 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.91930857 |
116 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.91702003 |
117 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.91681363 |
118 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.91622296 |
119 | ATF3_27146783_Chip-Seq_COLON_Human | 0.91590243 |
120 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.91128148 |
121 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.89773842 |
122 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.89158364 |
123 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.88563516 |
124 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.87986700 |
125 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.86741039 |
126 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.86529382 |
127 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86466882 |
128 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.85757761 |
129 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.85707425 |
130 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85377455 |
131 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.85192493 |
132 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.84753106 |
133 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.84050274 |
134 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.82472489 |
135 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.81706389 |
136 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.81428820 |
137 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.80940989 |
138 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.79742602 |
139 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.79475136 |
140 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.77537778 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.82909652 |
2 | MP0003111_abnormal_nucleus_morphology | 4.56268462 |
3 | MP0004957_abnormal_blastocyst_morpholog | 4.49108870 |
4 | MP0010094_abnormal_chromosome_stability | 4.38819802 |
5 | MP0003077_abnormal_cell_cycle | 3.85143623 |
6 | MP0008877_abnormal_DNA_methylation | 3.34141842 |
7 | MP0005623_abnormal_meninges_morphology | 3.01666074 |
8 | MP0008058_abnormal_DNA_repair | 2.91021011 |
9 | MP0008057_abnormal_DNA_replication | 2.83945503 |
10 | MP0005410_abnormal_fertilization | 2.75365289 |
11 | MP0008932_abnormal_embryonic_tissue | 2.68408713 |
12 | MP0001730_embryonic_growth_arrest | 2.65762543 |
13 | MP0002877_abnormal_melanocyte_morpholog | 2.60897281 |
14 | MP0008007_abnormal_cellular_replicative | 2.54876825 |
15 | MP0003123_paternal_imprinting | 2.37296702 |
16 | MP0010352_gastrointestinal_tract_polyps | 2.32678281 |
17 | MP0000566_synostosis | 2.29799974 |
18 | MP0000350_abnormal_cell_proliferation | 2.26881855 |
19 | MP0001929_abnormal_gametogenesis | 2.20929496 |
20 | MP0002210_abnormal_sex_determination | 2.11982671 |
21 | MP0003786_premature_aging | 2.06462148 |
22 | MP0002653_abnormal_ependyma_morphology | 2.06061109 |
23 | MP0003806_abnormal_nucleotide_metabolis | 1.89639272 |
24 | MP0010307_abnormal_tumor_latency | 1.85874891 |
25 | MP0001145_abnormal_male_reproductive | 1.82891008 |
26 | MP0010234_abnormal_vibrissa_follicle | 1.81678800 |
27 | MP0000678_abnormal_parathyroid_gland | 1.80760630 |
28 | MP0001346_abnormal_lacrimal_gland | 1.77284289 |
29 | MP0001697_abnormal_embryo_size | 1.73287724 |
30 | MP0003698_abnormal_male_reproductive | 1.73005076 |
31 | MP0000490_abnormal_crypts_of | 1.72071260 |
32 | MP0002080_prenatal_lethality | 1.71213586 |
33 | MP0003453_abnormal_keratinocyte_physiol | 1.68496396 |
34 | MP0008875_abnormal_xenobiotic_pharmacok | 1.66850215 |
35 | MP0005451_abnormal_body_composition | 1.66061450 |
36 | MP0004147_increased_porphyrin_level | 1.65265368 |
37 | MP0005380_embryogenesis_phenotype | 1.65075925 |
38 | MP0001672_abnormal_embryogenesis/_devel | 1.65075925 |
39 | MP0002160_abnormal_reproductive_system | 1.64136289 |
40 | MP0005377_hearing/vestibular/ear_phenot | 1.64038949 |
41 | MP0003878_abnormal_ear_physiology | 1.64038949 |
42 | MP0009780_abnormal_chondrocyte_physiolo | 1.60656457 |
43 | MP0000537_abnormal_urethra_morphology | 1.60541627 |
44 | MP0003718_maternal_effect | 1.60464053 |
45 | MP0000653_abnormal_sex_gland | 1.60381603 |
46 | MP0005257_abnormal_intraocular_pressure | 1.59168539 |
47 | MP0002085_abnormal_embryonic_tissue | 1.56044446 |
48 | MP0002084_abnormal_developmental_patter | 1.52375180 |
49 | MP0000579_abnormal_nail_morphology | 1.49101938 |
50 | MP0004272_abnormal_basement_membrane | 1.47252415 |
51 | MP0009379_abnormal_foot_pigmentation | 1.46763519 |
52 | MP0002060_abnormal_skin_morphology | 1.44675248 |
53 | MP0001545_abnormal_hematopoietic_system | 1.44206920 |
54 | MP0005397_hematopoietic_system_phenotyp | 1.44206920 |
55 | MP0003984_embryonic_growth_retardation | 1.42484930 |
56 | MP0003656_abnormal_erythrocyte_physiolo | 1.42174676 |
57 | MP0003950_abnormal_plasma_membrane | 1.41158869 |
58 | MP0000313_abnormal_cell_death | 1.37946419 |
59 | MP0002088_abnormal_embryonic_growth/wei | 1.37398622 |
60 | MP0000762_abnormal_tongue_morphology | 1.37143953 |
61 | MP0002019_abnormal_tumor_incidence | 1.36398947 |
62 | MP0004858_abnormal_nervous_system | 1.33709492 |
63 | MP0003941_abnormal_skin_development | 1.31620411 |
64 | MP0002086_abnormal_extraembryonic_tissu | 1.31211333 |
65 | MP0000467_abnormal_esophagus_morphology | 1.30956607 |
66 | MP0008260_abnormal_autophagy | 1.30765160 |
67 | MP0008438_abnormal_cutaneous_collagen | 1.27065331 |
68 | MP0004808_abnormal_hematopoietic_stem | 1.24338915 |
69 | MP0002396_abnormal_hematopoietic_system | 1.24104103 |
70 | MP0000358_abnormal_cell_content/ | 1.24028647 |
71 | MP0002098_abnormal_vibrissa_morphology | 1.23133154 |
72 | MP0002161_abnormal_fertility/fecundity | 1.22373126 |
73 | MP0002249_abnormal_larynx_morphology | 1.21351137 |
74 | MP0004185_abnormal_adipocyte_glucose | 1.21133757 |
75 | MP0001216_abnormal_epidermal_layer | 1.18714355 |
76 | MP0004197_abnormal_fetal_growth/weight/ | 1.17818670 |
77 | MP0006054_spinal_hemorrhage | 1.17623945 |
78 | MP0010030_abnormal_orbit_morphology | 1.16854197 |
79 | MP0005058_abnormal_lysosome_morphology | 1.16771293 |
80 | MP0005501_abnormal_skin_physiology | 1.14425696 |
81 | MP0001849_ear_inflammation | 1.14213566 |
82 | MP0006036_abnormal_mitochondrial_physio | 1.12002913 |
83 | MP0003315_abnormal_perineum_morphology | 1.11687676 |
84 | MP0000858_altered_metastatic_potential | 1.08584253 |
85 | MP0005409_darkened_coat_color | 1.08463416 |
86 | MP0003705_abnormal_hypodermis_morpholog | 1.05598961 |
87 | MP0005083_abnormal_biliary_tract | 1.04233364 |
88 | MP0004133_heterotaxia | 1.04097797 |
89 | MP0005389_reproductive_system_phenotype | 1.03958021 |
90 | MP0005076_abnormal_cell_differentiation | 1.01953788 |
91 | MP0010678_abnormal_skin_adnexa | 0.98343135 |
92 | MP0003566_abnormal_cell_adhesion | 0.98164267 |
93 | MP0000003_abnormal_adipose_tissue | 0.96797929 |
94 | MP0000733_abnormal_muscle_development | 0.93127874 |
95 | MP0002089_abnormal_postnatal_growth/wei | 0.92404805 |
96 | MP0010771_integument_phenotype | 0.92263304 |
97 | MP0006035_abnormal_mitochondrial_morpho | 0.90456738 |
98 | MP0002796_impaired_skin_barrier | 0.90037240 |
99 | MP0008995_early_reproductive_senescence | 0.89887923 |
100 | MP0000751_myopathy | 0.89660826 |
101 | MP0003942_abnormal_urinary_system | 0.89649184 |
102 | MP0004233_abnormal_muscle_weight | 0.87446468 |
103 | MP0003191_abnormal_cellular_cholesterol | 0.86652894 |
104 | MP0003091_abnormal_cell_migration | 0.85291272 |
105 | MP0003567_abnormal_fetal_cardiomyocyte | 0.84841023 |
106 | MP0004264_abnormal_extraembryonic_tissu | 0.84801576 |
107 | MP0003221_abnormal_cardiomyocyte_apopto | 0.84024769 |
108 | MP0001243_abnormal_dermal_layer | 0.83539352 |
109 | MP0005165_increased_susceptibility_to | 0.82936583 |
110 | MP0002092_abnormal_eye_morphology | 0.81644076 |
111 | MP0005499_abnormal_olfactory_system | 0.78778012 |
112 | MP0005394_taste/olfaction_phenotype | 0.78778012 |
113 | MP0000534_abnormal_ureter_morphology | 0.78233770 |
114 | MP0000477_abnormal_intestine_morphology | 0.78137269 |
115 | MP0005384_cellular_phenotype | 0.77598940 |
116 | MP0000627_abnormal_mammary_gland | 0.77514077 |
117 | MP0002697_abnormal_eye_size | 0.76947947 |
118 | MP0001293_anophthalmia | 0.76866769 |
119 | MP0003186_abnormal_redox_activity | 0.76243726 |
120 | MP0003646_muscle_fatigue | 0.76069460 |
121 | MP0004782_abnormal_surfactant_physiolog | 0.75138807 |
122 | MP0005266_abnormal_metabolism | 0.73249775 |
123 | MP0005023_abnormal_wound_healing | 0.72201753 |
124 | MP0005621_abnormal_cell_physiology | 0.72098663 |
125 | MP0005330_cardiomyopathy | 0.71609412 |
126 | MP0002269_muscular_atrophy | 0.70935268 |
127 | MP0001881_abnormal_mammary_gland | 0.69940517 |
128 | MP0001119_abnormal_female_reproductive | 0.69162942 |
129 | MP0003115_abnormal_respiratory_system | 0.69113797 |
130 | MP0009053_abnormal_anal_canal | 0.67818656 |
131 | MP0003121_genomic_imprinting | 0.67503577 |
132 | MP0002132_abnormal_respiratory_system | 0.67083284 |
133 | MP0001984_abnormal_olfaction | 0.66938381 |
134 | MP0003699_abnormal_female_reproductive | 0.65695574 |
135 | MP0004084_abnormal_cardiac_muscle | 0.64893667 |
136 | MP0000750_abnormal_muscle_regeneration | 0.63545800 |
137 | MP0009333_abnormal_splenocyte_physiolog | 0.63203379 |
138 | MP0003283_abnormal_digestive_organ | 0.61587068 |
139 | MP0001727_abnormal_embryo_implantation | 0.61158949 |
140 | MP0003119_abnormal_digestive_system | 0.59960365 |
141 | MP0008770_decreased_survivor_rate | 0.59681402 |
142 | MP0009278_abnormal_bone_marrow | 0.59359869 |
143 | MP0009672_abnormal_birth_weight | 0.57483404 |
144 | MP0008789_abnormal_olfactory_epithelium | 0.54834637 |
145 | MP0003866_abnormal_defecation | 0.54254737 |
146 | MP0002111_abnormal_tail_morphology | 0.53825818 |
147 | MP0001919_abnormal_reproductive_system | 0.53408687 |
148 | MP0009703_decreased_birth_body | 0.51302701 |
149 | MP0000703_abnormal_thymus_morphology | 0.50748354 |
150 | MP0002234_abnormal_pharynx_morphology | 0.50657710 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.04828157 |
2 | Chronic bronchitis (HP:0004469) | 4.82106024 |
3 | Rhinitis (HP:0012384) | 4.33909104 |
4 | Abnormal respiratory motile cilium physiology (HP:0012261) | 4.21601791 |
5 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.07131586 |
6 | Abnormal number of erythroid precursors (HP:0012131) | 3.85830394 |
7 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.71138160 |
8 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.71138160 |
9 | Selective tooth agenesis (HP:0001592) | 3.67607849 |
10 | Short nail (HP:0001799) | 3.59477873 |
11 | Breast hypoplasia (HP:0003187) | 3.52788272 |
12 | Birth length less than 3rd percentile (HP:0003561) | 3.44308390 |
13 | Abnormality of the distal phalanges of the toes (HP:0010182) | 3.31783458 |
14 | Oral leukoplakia (HP:0002745) | 3.24153779 |
15 | 11 pairs of ribs (HP:0000878) | 3.22876570 |
16 | Degeneration of anterior horn cells (HP:0002398) | 3.20897127 |
17 | Abnormality of the anterior horn cell (HP:0006802) | 3.20897127 |
18 | Absent/shortened dynein arms (HP:0200106) | 3.13461320 |
19 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.13461320 |
20 | Carpal bone hypoplasia (HP:0001498) | 3.12798688 |
21 | Ependymoma (HP:0002888) | 3.02769479 |
22 | Reticulocytopenia (HP:0001896) | 3.02071865 |
23 | Impulsivity (HP:0100710) | 2.92422884 |
24 | Abnormal ciliary motility (HP:0012262) | 2.92219899 |
25 | Atelectasis (HP:0100750) | 2.90788845 |
26 | Premature rupture of membranes (HP:0001788) | 2.87012205 |
27 | Nasal polyposis (HP:0100582) | 2.86800474 |
28 | Colon cancer (HP:0003003) | 2.85253210 |
29 | Distal lower limb muscle weakness (HP:0009053) | 2.71791745 |
30 | Distal upper limb amyotrophy (HP:0007149) | 2.69245739 |
31 | Upper limb amyotrophy (HP:0009129) | 2.69245739 |
32 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.68292066 |
33 | Supernumerary spleens (HP:0009799) | 2.67518330 |
34 | Recurrent otitis media (HP:0000403) | 2.59756169 |
35 | Trismus (HP:0000211) | 2.57647380 |
36 | Patellar aplasia (HP:0006443) | 2.54684040 |
37 | Broad distal phalanx of finger (HP:0009836) | 2.51648115 |
38 | Bronchiectasis (HP:0002110) | 2.51419776 |
39 | Cerebral hypomyelination (HP:0006808) | 2.51015041 |
40 | Hyperacusis (HP:0010780) | 2.48026824 |
41 | Microretrognathia (HP:0000308) | 2.47591604 |
42 | Missing ribs (HP:0000921) | 2.47115373 |
43 | Premature ovarian failure (HP:0008209) | 2.45864833 |
44 | Abnormality of the nasal mucosa (HP:0000433) | 2.45556296 |
45 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.43092822 |
46 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.42341982 |
47 | Hand muscle atrophy (HP:0009130) | 2.41595583 |
48 | Achilles tendon contracture (HP:0001771) | 2.40596638 |
49 | Medulloblastoma (HP:0002885) | 2.39775154 |
50 | Abnormal spermatogenesis (HP:0008669) | 2.39230919 |
51 | Ulnar bowing (HP:0003031) | 2.38958882 |
52 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.37758375 |
53 | Bronchitis (HP:0012387) | 2.37267779 |
54 | Absent thumb (HP:0009777) | 2.35525461 |
55 | Neoplasm of the pancreas (HP:0002894) | 2.29838089 |
56 | Rhabdomyosarcoma (HP:0002859) | 2.29828641 |
57 | Flat acetabular roof (HP:0003180) | 2.27051995 |
58 | Spinal cord compression (HP:0002176) | 2.26062605 |
59 | Rough bone trabeculation (HP:0100670) | 2.23272300 |
60 | Abnormality of the umbilical cord (HP:0010881) | 2.22976156 |
61 | Infertility (HP:0000789) | 2.20786085 |
62 | Abdominal situs inversus (HP:0003363) | 2.18032119 |
63 | Abnormality of abdominal situs (HP:0011620) | 2.18032119 |
64 | Macrocytic anemia (HP:0001972) | 2.17858353 |
65 | Abnormality of the Achilles tendon (HP:0005109) | 2.17811072 |
66 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.16788026 |
67 | Aplastic anemia (HP:0001915) | 2.14090182 |
68 | Abnormality of the preputium (HP:0100587) | 2.14052204 |
69 | Duodenal stenosis (HP:0100867) | 2.12469938 |
70 | Small intestinal stenosis (HP:0012848) | 2.12469938 |
71 | Biliary tract neoplasm (HP:0100574) | 2.12193297 |
72 | Multiple enchondromatosis (HP:0005701) | 2.11521149 |
73 | Sloping forehead (HP:0000340) | 2.09880805 |
74 | Limb-girdle muscle atrophy (HP:0003797) | 2.09033563 |
75 | Bell-shaped thorax (HP:0001591) | 2.08506754 |
76 | Angiofibromas (HP:0010615) | 2.07814202 |
77 | Adenoma sebaceum (HP:0009720) | 2.07814202 |
78 | Facial cleft (HP:0002006) | 2.07126488 |
79 | Cholecystitis (HP:0001082) | 2.06888640 |
80 | Abnormal gallbladder physiology (HP:0012438) | 2.06888640 |
81 | Distal lower limb amyotrophy (HP:0008944) | 2.06582222 |
82 | Progressive muscle weakness (HP:0003323) | 2.03914730 |
83 | Abnormality of reticulocytes (HP:0004312) | 2.03157894 |
84 | Chromsome breakage (HP:0040012) | 2.02988999 |
85 | Abnormality of the labia minora (HP:0012880) | 2.01070859 |
86 | Vertebral compression fractures (HP:0002953) | 2.01015944 |
87 | Occipital encephalocele (HP:0002085) | 2.00007225 |
88 | Abnormality of the lower motor neuron (HP:0002366) | 1.99165131 |
89 | Pallor (HP:0000980) | 1.98765161 |
90 | Meckel diverticulum (HP:0002245) | 1.98175156 |
91 | Basal cell carcinoma (HP:0002671) | 1.97958434 |
92 | Pelvic girdle muscle weakness (HP:0003749) | 1.97633826 |
93 | Abnormality of carpal bone ossification (HP:0006257) | 1.96724957 |
94 | Glossoptosis (HP:0000162) | 1.96309266 |
95 | Abnormality of dentin (HP:0010299) | 1.94128067 |
96 | Abnormality of chromosome stability (HP:0003220) | 1.93516171 |
97 | Male infertility (HP:0003251) | 1.93203032 |
98 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.92700294 |
99 | Protrusio acetabuli (HP:0003179) | 1.90925504 |
100 | Increased nuchal translucency (HP:0010880) | 1.90698339 |
101 | Secondary amenorrhea (HP:0000869) | 1.90379416 |
102 | Neoplasm of the colon (HP:0100273) | 1.88883252 |
103 | Flattened epiphyses (HP:0003071) | 1.88266389 |
104 | Deviation of the thumb (HP:0009603) | 1.87851352 |
105 | Glucose intolerance (HP:0000833) | 1.87205143 |
106 | Overlapping toe (HP:0001845) | 1.86042905 |
107 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.85536337 |
108 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.85536337 |
109 | Single umbilical artery (HP:0001195) | 1.85536337 |
110 | Ovarian neoplasm (HP:0100615) | 1.85470494 |
111 | Abnormality of the ileum (HP:0001549) | 1.84249827 |
112 | Hyperactive renin-angiotensin system (HP:0000841) | 1.82697144 |
113 | Proximal placement of thumb (HP:0009623) | 1.82092104 |
114 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.81934478 |
115 | Shoulder girdle muscle weakness (HP:0003547) | 1.81368860 |
116 | Astrocytoma (HP:0009592) | 1.81215880 |
117 | Abnormality of the astrocytes (HP:0100707) | 1.81215880 |
118 | Self-mutilation (HP:0000742) | 1.80871342 |
119 | Broad face (HP:0000283) | 1.80203031 |
120 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.80184043 |
121 | Osteolytic defects of the hand bones (HP:0009699) | 1.80184043 |
122 | Stridor (HP:0010307) | 1.79140906 |
123 | Intestinal polyp (HP:0005266) | 1.79058345 |
124 | Pili torti (HP:0003777) | 1.78440495 |
125 | Neoplasm of the rectum (HP:0100743) | 1.78398118 |
126 | Elbow flexion contracture (HP:0002987) | 1.78378140 |
127 | Difficulty climbing stairs (HP:0003551) | 1.78018894 |
128 | Insomnia (HP:0100785) | 1.77961898 |
129 | Abnormal ossification of hand bones (HP:0005921) | 1.77615660 |
130 | Absent epiphyses (HP:0010577) | 1.77437471 |
131 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.77437471 |
132 | Recurrent sinusitis (HP:0011108) | 1.76228278 |
133 | Intestinal polyposis (HP:0200008) | 1.75934598 |
134 | High pitched voice (HP:0001620) | 1.74647216 |
135 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.74324382 |
136 | Increased connective tissue (HP:0009025) | 1.73877321 |
137 | Myelodysplasia (HP:0002863) | 1.73723098 |
138 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.73055784 |
139 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.72478016 |
140 | Back pain (HP:0003418) | 1.71712111 |
141 | Diaphragmatic weakness (HP:0009113) | 1.71675388 |
142 | Absent radius (HP:0003974) | 1.71535349 |
143 | Abnormal lung lobation (HP:0002101) | 1.71213761 |
144 | Prominent nose (HP:0000448) | 1.70677727 |
145 | Cafe-au-lait spot (HP:0000957) | 1.70148963 |
146 | Irregular epiphyses (HP:0010582) | 1.70136240 |
147 | Emotional lability (HP:0000712) | 1.70131275 |
148 | Ragged-red muscle fibers (HP:0003200) | 1.69220744 |
149 | Progressive hearing impairment (HP:0001730) | 1.68409859 |
150 | Natal tooth (HP:0000695) | 1.65173390 |
151 | Down-sloping shoulders (HP:0200021) | 1.65088382 |
152 | Spinal rigidity (HP:0003306) | 1.64230735 |
153 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.57822816 |
154 | Absent frontal sinuses (HP:0002688) | 1.55328518 |
155 | Abnormal trabecular bone morphology (HP:0100671) | 1.54161736 |
156 | Fragile skin (HP:0001030) | 1.53564189 |
157 | Chronic sinusitis (HP:0011109) | 1.52690868 |
158 | Flared metaphyses (HP:0003015) | 1.51437703 |
159 | Entropion (HP:0000621) | 1.50978502 |
160 | Vascular calcification (HP:0004934) | 1.49786681 |
161 | Progressive sensorineural hearing impairment (HP:0000408) | 1.49025307 |
162 | Bifid scrotum (HP:0000048) | 1.46576505 |
163 | Sparse eyelashes (HP:0000653) | 1.44822865 |
164 | Ankyloglossia (HP:0010296) | 1.43769321 |
165 | Long palpebral fissure (HP:0000637) | 1.43328210 |
166 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.41974341 |
167 | Abnormality of glycolysis (HP:0004366) | 1.41881697 |
168 | Abnormality of the acetabulum (HP:0003170) | 1.41035768 |
169 | Generalized amyotrophy (HP:0003700) | 1.40561090 |
170 | Cervical subluxation (HP:0003308) | 1.40256315 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.04139983 |
2 | WEE1 | 4.40162508 |
3 | CDC7 | 3.67993244 |
4 | SMG1 | 3.46528182 |
5 | NEK2 | 3.05404170 |
6 | NEK1 | 2.91837736 |
7 | PDK3 | 2.79685129 |
8 | PDK4 | 2.79685129 |
9 | PBK | 2.64119049 |
10 | MST1R | 2.61271527 |
11 | MAPK15 | 2.59075705 |
12 | TTK | 2.41987628 |
13 | TESK1 | 2.32660138 |
14 | EEF2K | 2.27345728 |
15 | BRSK2 | 2.17366081 |
16 | EIF2AK1 | 2.16718043 |
17 | IRAK3 | 2.02999106 |
18 | MAPKAPK3 | 2.01170507 |
19 | PLK1 | 1.90479035 |
20 | RPS6KB2 | 1.89955552 |
21 | BRSK1 | 1.84519982 |
22 | TESK2 | 1.84337899 |
23 | SCYL2 | 1.80854700 |
24 | VRK2 | 1.79810375 |
25 | AURKA | 1.67324565 |
26 | STK10 | 1.63583986 |
27 | AURKB | 1.62895292 |
28 | DYRK3 | 1.57087665 |
29 | TSSK6 | 1.51334116 |
30 | PDK2 | 1.43551333 |
31 | TRIB3 | 1.42582651 |
32 | NME2 | 1.39093127 |
33 | MAP3K8 | 1.39019279 |
34 | MET | 1.36236440 |
35 | ACVR1B | 1.32883103 |
36 | EPHA2 | 1.32066920 |
37 | RPS6KA4 | 1.30815098 |
38 | CDK7 | 1.27164687 |
39 | PKN2 | 1.26300132 |
40 | PNCK | 1.26249521 |
41 | CCNB1 | 1.25504816 |
42 | PLK4 | 1.23753642 |
43 | SIK1 | 1.21977127 |
44 | VRK1 | 1.21215366 |
45 | PTK2 | 1.19337254 |
46 | PASK | 1.19179506 |
47 | PAK4 | 1.18934554 |
48 | ATR | 1.14591100 |
49 | PLK3 | 1.10100818 |
50 | CHEK2 | 1.09373403 |
51 | TAOK2 | 1.06562488 |
52 | LMTK2 | 1.05124545 |
53 | CDK4 | 1.02463082 |
54 | STK16 | 1.01569769 |
55 | SRPK1 | 1.01154662 |
56 | BRAF | 1.00936087 |
57 | CHEK1 | 0.97340311 |
58 | CDK12 | 0.97054490 |
59 | LRRK2 | 0.93448402 |
60 | MAP3K10 | 0.93034502 |
61 | PAK1 | 0.92236459 |
62 | LATS2 | 0.92027092 |
63 | TLK1 | 0.87359525 |
64 | MAP3K11 | 0.87127159 |
65 | PIM2 | 0.84770213 |
66 | ERN1 | 0.82412489 |
67 | PRPF4B | 0.82137816 |
68 | EIF2AK3 | 0.75256409 |
69 | LIMK1 | 0.73418322 |
70 | PRKCI | 0.72773884 |
71 | ERBB4 | 0.72193729 |
72 | TGFBR1 | 0.71242339 |
73 | MAP2K2 | 0.70065445 |
74 | ICK | 0.68682491 |
75 | PRKD3 | 0.65891222 |
76 | FLT3 | 0.63465626 |
77 | PTK6 | 0.62973040 |
78 | STK4 | 0.62787012 |
79 | MAP3K2 | 0.60524242 |
80 | ATM | 0.58971081 |
81 | PDGFRA | 0.58204522 |
82 | ARAF | 0.57932953 |
83 | CDK2 | 0.57462217 |
84 | MST4 | 0.55890237 |
85 | NTRK1 | 0.55288791 |
86 | ILK | 0.54211869 |
87 | STK3 | 0.52974860 |
88 | MATK | 0.52756906 |
89 | TAOK1 | 0.51992679 |
90 | ABL2 | 0.51890505 |
91 | MAP3K12 | 0.50997933 |
92 | KSR2 | 0.49585422 |
93 | CSNK2A2 | 0.48762775 |
94 | EPHB1 | 0.47829618 |
95 | EPHB2 | 0.45879474 |
96 | BMX | 0.45569262 |
97 | MAP2K3 | 0.43896354 |
98 | CDK8 | 0.43196046 |
99 | CDK18 | 0.42705048 |
100 | MTOR | 0.42291945 |
101 | ALK | 0.42091645 |
102 | CDK9 | 0.41600934 |
103 | CSNK2A1 | 0.41313431 |
104 | AKT2 | 0.39722201 |
105 | CLK1 | 0.39648608 |
106 | CDK1 | 0.39400536 |
107 | MELK | 0.39250742 |
108 | CDK6 | 0.38530045 |
109 | PAK2 | 0.38354039 |
110 | CAMK2G | 0.38113125 |
111 | FGFR4 | 0.37563500 |
112 | MAP3K3 | 0.37459943 |
113 | MAPK11 | 0.36952342 |
114 | STK38L | 0.36740929 |
115 | MAPKAPK2 | 0.36283643 |
116 | KDR | 0.35759358 |
117 | NME1 | 0.35694085 |
118 | TTN | 0.35363699 |
119 | MOS | 0.33553386 |
120 | RIPK1 | 0.33303015 |
121 | MYLK | 0.33199049 |
122 | PIM1 | 0.33030068 |
123 | MINK1 | 0.31822804 |
124 | CDK14 | 0.31521836 |
125 | CSNK1E | 0.31190837 |
126 | MKNK1 | 0.30601799 |
127 | BCKDK | 0.30453936 |
128 | CDK11A | 0.29724841 |
129 | CDK15 | 0.27845557 |
130 | GRK6 | 0.27155261 |
131 | DAPK1 | 0.27001396 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 5.07852301 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.09196804 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.36014259 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.34270846 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.13331858 |
6 | Cell cycle_Homo sapiens_hsa04110 | 3.01555906 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.95506903 |
8 | Spliceosome_Homo sapiens_hsa03040 | 2.87701245 |
9 | Ribosome_Homo sapiens_hsa03010 | 2.86149623 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.84067734 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 2.71867786 |
12 | RNA polymerase_Homo sapiens_hsa03020 | 2.69431824 |
13 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.51077300 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.50053992 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.44958468 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.95827866 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.90982509 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.90612510 |
19 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.81490855 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.67107474 |
21 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.59543849 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.59229503 |
23 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.58615960 |
24 | RNA degradation_Homo sapiens_hsa03018 | 1.51950757 |
25 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.50607962 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.45426601 |
27 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.43101431 |
28 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.36608614 |
29 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.33419862 |
30 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.33185427 |
31 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.31869581 |
32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.30978475 |
33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.27095784 |
34 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.26909469 |
35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.18469135 |
36 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.18456918 |
37 | Sulfur relay system_Homo sapiens_hsa04122 | 1.11558881 |
38 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10576905 |
39 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.10560043 |
40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.10470223 |
41 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.09624373 |
42 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.06877796 |
43 | Adherens junction_Homo sapiens_hsa04520 | 1.04479008 |
44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.01901655 |
45 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.01653903 |
46 | Thyroid cancer_Homo sapiens_hsa05216 | 0.98412090 |
47 | Parkinsons disease_Homo sapiens_hsa05012 | 0.98376364 |
48 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.97850147 |
49 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.91516812 |
50 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.91007515 |
51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.91006459 |
52 | Histidine metabolism_Homo sapiens_hsa00340 | 0.89797220 |
53 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.87320702 |
54 | Prion diseases_Homo sapiens_hsa05020 | 0.81752513 |
55 | Alcoholism_Homo sapiens_hsa05034 | 0.78002893 |
56 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.77812130 |
57 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.77460095 |
58 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.77352487 |
59 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.73810959 |
60 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.72417951 |
61 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.71452812 |
62 | * Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.69031554 |
63 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.67673778 |
64 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.67400900 |
65 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.67389479 |
66 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.66344562 |
67 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.66216330 |
68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.64684664 |
69 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.63827427 |
70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.63259986 |
71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.62324705 |
72 | Bladder cancer_Homo sapiens_hsa05219 | 0.58281563 |
73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58134708 |
74 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.56631701 |
75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.55979372 |
76 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.55157532 |
77 | Other glycan degradation_Homo sapiens_hsa00511 | 0.54507841 |
78 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.52655918 |
79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52113102 |
80 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.51606510 |
81 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.50585732 |
82 | Focal adhesion_Homo sapiens_hsa04510 | 0.49648529 |
83 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.48970899 |
84 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.47504175 |
85 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.46691432 |
86 | Prostate cancer_Homo sapiens_hsa05215 | 0.46081972 |
87 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45353581 |
88 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.45003464 |
89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42680381 |
90 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.41580727 |
91 | Tight junction_Homo sapiens_hsa04530 | 0.40850303 |
92 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.40732843 |
93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.40194670 |
94 | Apoptosis_Homo sapiens_hsa04210 | 0.39772579 |
95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.37884373 |
96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36548211 |
97 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.34941749 |
98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.34659737 |
99 | Lysine degradation_Homo sapiens_hsa00310 | 0.33149301 |
100 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.30418389 |
101 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.29032619 |
102 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.28604005 |
103 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.28474149 |
104 | Galactose metabolism_Homo sapiens_hsa00052 | 0.27553585 |
105 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25677566 |
106 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.25610316 |
107 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.25585214 |
108 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.24573832 |
109 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.24424079 |
110 | Alzheimers disease_Homo sapiens_hsa05010 | 0.23457898 |
111 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.23304560 |
112 | Legionellosis_Homo sapiens_hsa05134 | 0.23082359 |
113 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.23037392 |
114 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.22858478 |
115 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.22636908 |
116 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.22634217 |
117 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.22236046 |
118 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.21318917 |
119 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.18762194 |
120 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.18621056 |
121 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.17412901 |
122 | Shigellosis_Homo sapiens_hsa05131 | 0.16041612 |
123 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.15948965 |
124 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.13599257 |
125 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.13195534 |
126 | Endometrial cancer_Homo sapiens_hsa05213 | 0.12136025 |
127 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.11874762 |
128 | Pathways in cancer_Homo sapiens_hsa05200 | 0.11429392 |
129 | Olfactory transduction_Homo sapiens_hsa04740 | 0.11371814 |
130 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.10293033 |
131 | Hepatitis B_Homo sapiens_hsa05161 | 0.10006639 |
132 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.09161152 |