TUBB6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1wound healing, spreading of epidermal cells (GO:0035313)4.60809176
2chondrocyte proliferation (GO:0035988)4.00616646
3wound healing, spreading of cells (GO:0044319)3.96341320
4negative regulation of nitric-oxide synthase activity (GO:0051001)3.95430710
5protein localization to endosome (GO:0036010)3.90823286
6cell adhesion mediated by integrin (GO:0033627)3.84607748
7barbed-end actin filament capping (GO:0051016)3.81797517
8endodermal cell differentiation (GO:0035987)3.74750264
9collagen fibril organization (GO:0030199)3.53124149
10substrate-dependent cell migration (GO:0006929)3.46497772
11negative regulation of chondrocyte differentiation (GO:0032331)3.40224125
12regulation of integrin-mediated signaling pathway (GO:2001044)3.38869102
13extracellular fibril organization (GO:0043206)3.36259370
14protein maturation by protein folding (GO:0022417)3.34988911
15cell migration involved in heart development (GO:0060973)3.33119594
16dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.26250421
17protein heterotrimerization (GO:0070208)3.18508351
18adherens junction assembly (GO:0034333)3.16042352
19skin morphogenesis (GO:0043589)3.16036003
20focal adhesion assembly (GO:0048041)3.13578874
21cell-substrate adherens junction assembly (GO:0007045)3.13578874
22protein localization to kinetochore (GO:0034501)3.12390789
23positive regulation of endothelial cell apoptotic process (GO:2000353)3.11953308
24basement membrane organization (GO:0071711)3.08969493
25heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.06139923
26kidney mesenchyme development (GO:0072074)3.03009298
27regulation of mitotic spindle organization (GO:0060236)3.01212986
28type B pancreatic cell proliferation (GO:0044342)3.00477166
29regulation of SMAD protein import into nucleus (GO:0060390)2.99977088
30positive regulation of epithelial to mesenchymal transition (GO:0010718)2.96162866
31regulation of tight junction assembly (GO:2000810)2.95672206
32negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.93369375
33regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.92859630
34cellular response to vitamin (GO:0071295)2.91774707
35mitotic nuclear envelope disassembly (GO:0007077)2.90970974
36pinocytosis (GO:0006907)2.90879971
37planar cell polarity pathway involved in neural tube closure (GO:0090179)2.90462147
38regulation of spindle organization (GO:0090224)2.87902547
39hyaluronan catabolic process (GO:0030214)2.87744557
40atrioventricular valve morphogenesis (GO:0003181)2.87679478
41paraxial mesoderm development (GO:0048339)2.86822468
42adhesion of symbiont to host cell (GO:0044650)2.84044068
43virion attachment to host cell (GO:0019062)2.84044068
44negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.83790012
45negative regulation of smooth muscle cell migration (GO:0014912)2.82127096
46positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.81306053
47regulation of early endosome to late endosome transport (GO:2000641)2.80935245
48vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.80779575
49ventricular cardiac muscle cell development (GO:0055015)2.80402824
50mitotic nuclear envelope reassembly (GO:0007084)2.79691571
51nuclear envelope reassembly (GO:0031468)2.79691571
52nuclear envelope disassembly (GO:0051081)2.74947379
53membrane disassembly (GO:0030397)2.74947379
54desmosome organization (GO:0002934)2.74235591
55sprouting angiogenesis (GO:0002040)2.74204647
56regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.73404411
57regulation of integrin activation (GO:0033623)2.72762027
58cell migration involved in sprouting angiogenesis (GO:0002042)2.72592602
59lymphangiogenesis (GO:0001946)2.71080963
60sequestering of extracellular ligand from receptor (GO:0035581)2.70785749
61notochord development (GO:0030903)2.70309169
62apoptotic cell clearance (GO:0043277)2.68689359
63multicellular organismal metabolic process (GO:0044236)2.68681040
64extracellular matrix assembly (GO:0085029)2.67998722
65regulation of protein heterodimerization activity (GO:0043497)2.67427377
66regulation of transforming growth factor beta2 production (GO:0032909)2.66724353
67multicellular organismal catabolic process (GO:0044243)2.65332408
68endothelial cell morphogenesis (GO:0001886)2.64689289
69regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.63511195
70positive regulation of actin filament depolymerization (GO:0030836)2.62625947
71mitotic metaphase plate congression (GO:0007080)2.62506826
72positive regulation of SMAD protein import into nucleus (GO:0060391)2.61022540
73negative regulation of monooxygenase activity (GO:0032769)2.60874278
74adhesion of symbiont to host (GO:0044406)2.57019312
75cellular response to interferon-alpha (GO:0035457)2.56792168
76negative regulation of protein localization to cell surface (GO:2000009)2.56653568
77cellular response to vitamin D (GO:0071305)2.56310643
78epithelial cell-cell adhesion (GO:0090136)2.55804002
79negative regulation of stem cell proliferation (GO:2000647)2.54217365
80actin filament depolymerization (GO:0030042)2.54210655
81negative regulation of cartilage development (GO:0061037)2.53041678
82heart trabecula formation (GO:0060347)2.51225074
83hypotonic response (GO:0006971)2.51138289
84muscle cell migration (GO:0014812)2.49958080
85glial cell migration (GO:0008347)2.49912889
86blood vessel endothelial cell migration (GO:0043534)2.48487829
87T cell apoptotic process (GO:0070231)2.47944333
88substrate adhesion-dependent cell spreading (GO:0034446)2.46735572
89folic acid-containing compound biosynthetic process (GO:0009396)2.45904964
90histone-serine phosphorylation (GO:0035404)2.44737345
91extracellular matrix organization (GO:0030198)2.43970977
92ribosome assembly (GO:0042255)2.43776097
93formation of translation preinitiation complex (GO:0001731)2.43690882
94extracellular structure organization (GO:0043062)2.43049775
95positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.41604395
96negative regulation of fatty acid transport (GO:2000192)2.41232754
97hippo signaling (GO:0035329)2.40371917
98plasma membrane repair (GO:0001778)2.40099500
99protein localization to chromosome, centromeric region (GO:0071459)2.39331871
100vascular endothelial growth factor signaling pathway (GO:0038084)2.39073490
101venous blood vessel morphogenesis (GO:0048845)2.38695021
102nuclear pore complex assembly (GO:0051292)2.38114703
103negative regulation of anoikis (GO:2000811)2.37990965
104nuclear pore organization (GO:0006999)2.36412160
105maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.35808110
106vagina development (GO:0060068)2.35149512
107platelet aggregation (GO:0070527)2.34800116
108Golgi transport vesicle coating (GO:0048200)2.33692076
109COPI coating of Golgi vesicle (GO:0048205)2.33692076
110collagen metabolic process (GO:0032963)2.32791939
111peptidyl-proline hydroxylation (GO:0019511)2.32373964
112regulation of cell aging (GO:0090342)2.28185963
113myeloid cell homeostasis (GO:0002262)2.28037381
114establishment of chromosome localization (GO:0051303)2.27349294
115regulation of metalloenzyme activity (GO:0048552)2.27144997
116protein hydroxylation (GO:0018126)2.25404930
117mRNA transcription (GO:0009299)2.24849887
118positive regulation of macrophage activation (GO:0043032)2.24840520
119membrane raft organization (GO:0031579)2.24580951
120positive regulation of blood vessel endothelial cell migration (GO:0043536)2.23615869
121lung morphogenesis (GO:0060425)2.23308444
122cell-substrate junction assembly (GO:0007044)2.20412225
123positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.19302183
124nodal signaling pathway (GO:0038092)2.19290276
125mesodermal cell differentiation (GO:0048333)2.18841713
126branching involved in salivary gland morphogenesis (GO:0060445)2.18627367
127retina vasculature morphogenesis in camera-type eye (GO:0061299)2.18598482
128fibril organization (GO:0097435)2.18190246
129bone trabecula formation (GO:0060346)2.16319184
130positive regulation of protein import into nucleus, translocation (GO:0033160)2.15385133
131mitotic cytokinesis (GO:0000281)2.15179885
132protein retention in ER lumen (GO:0006621)2.15015957
133dermatan sulfate biosynthetic process (GO:0030208)2.14816058
134collagen catabolic process (GO:0030574)2.14573751
135extracellular matrix disassembly (GO:0022617)2.14500768
136nucleobase-containing small molecule interconversion (GO:0015949)2.14476384
137nuclear envelope organization (GO:0006998)2.14271851
138metaphase plate congression (GO:0051310)2.13957680
139negative regulation of smooth muscle cell differentiation (GO:0051151)2.12050362
140epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.12033639
141positive regulation of osteoblast proliferation (GO:0033690)2.11845701
142heterochromatin organization (GO:0070828)2.11152784
143morphogenesis of an endothelium (GO:0003159)2.11016617
144endothelial tube morphogenesis (GO:0061154)2.11016617
145stress fiber assembly (GO:0043149)2.10067651
146regulation of gene silencing by RNA (GO:0060966)2.09621538
147regulation of posttranscriptional gene silencing (GO:0060147)2.09621538
148regulation of gene silencing by miRNA (GO:0060964)2.09621538
149hemidesmosome assembly (GO:0031581)2.09295364
150actin-myosin filament sliding (GO:0033275)2.07897168
151muscle filament sliding (GO:0030049)2.07897168
152multicellular organismal macromolecule metabolic process (GO:0044259)2.07678645

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.95927891
2E2F7_22180533_ChIP-Seq_HELA_Human3.80550198
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.80285070
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.79362026
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.52461168
6* RARG_19884340_ChIP-ChIP_MEFs_Mouse3.51417045
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.26474806
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.03342278
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.72109327
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.71037274
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.57760833
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.34081839
13RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.32669036
14HIF1A_21447827_ChIP-Seq_MCF-7_Human2.20537313
15AR_21909140_ChIP-Seq_LNCAP_Human2.16895271
16CLOCK_20551151_ChIP-Seq_293T_Human2.14075884
17NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.12051125
18SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.09235946
19* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.01536034
20ATF3_23680149_ChIP-Seq_GBM1-GSC_Human2.00082086
21RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.98793594
22* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.95849203
23ELK3_25401928_ChIP-Seq_HUVEC_Human1.93671714
24ZNF263_19887448_ChIP-Seq_K562_Human1.91034182
25MYC_19079543_ChIP-ChIP_MESCs_Mouse1.90346134
26PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.85463553
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.75694925
28* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.74903764
29* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.74903764
30SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.73777629
31PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.69300229
32* ATF3_27146783_Chip-Seq_COLON_Human1.69077445
33E2F4_17652178_ChIP-ChIP_JURKAT_Human1.66720472
34HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.61271360
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.60570037
36* BRD4_25478319_ChIP-Seq_HGPS_Human1.60554581
37MYC_19030024_ChIP-ChIP_MESCs_Mouse1.60118350
38IRF8_21731497_ChIP-ChIP_J774_Mouse1.54512705
39STAT3_1855785_ChIP-Seq_MESCs_Mouse1.53161171
40KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.50762298
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.49328081
42ELK1_19687146_ChIP-ChIP_HELA_Human1.47674187
43ELK1_22589737_ChIP-Seq_MCF10A_Human1.44482569
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.44382266
45WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43876085
46MYC_18358816_ChIP-ChIP_MESCs_Mouse1.43855543
47CJUN_26792858_Chip-Seq_BT549_Human1.41637393
48* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.41537914
49XRN2_22483619_ChIP-Seq_HELA_Human1.41491436
50GATA2_21666600_ChIP-Seq_HMVEC_Human1.41179033
51CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.38488098
52STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.37747444
53CREB1_15753290_ChIP-ChIP_HEK293T_Human1.36920398
54TCF3_18692474_ChIP-Seq_MEFs_Mouse1.36580490
55LXR_22292898_ChIP-Seq_THP-1_Human1.34922067
56DCP1A_22483619_ChIP-Seq_HELA_Human1.32948994
57* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.30444047
58UBF1/2_26484160_Chip-Seq_HMECs_Human1.28406322
59EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.28115571
60TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.26908867
61TFEB_21752829_ChIP-Seq_HELA_Human1.26622605
62TP53_22127205_ChIP-Seq_IMR90_Human1.25958545
63SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24507362
64KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.24209086
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.23945618
66SOX9_24532713_ChIP-Seq_HFSC_Mouse1.22549377
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.22509595
68NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.21410247
69ESR2_21235772_ChIP-Seq_MCF-7_Human1.21073112
70ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.20571582
71TBX20_22080862_ChIP-Seq_HEART_Mouse1.18293067
72TBX20_22328084_ChIP-Seq_HEART_Mouse1.18293067
73MYB_21317192_ChIP-Seq_ERMYB_Mouse1.17826564
74* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.17188621
75NANOG_18555785_ChIP-Seq_MESCs_Mouse1.16668803
76MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.16375450
77GABP_17652178_ChIP-ChIP_JURKAT_Human1.16356065
78* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13172076
79MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.13076544
80* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12971847
81SMC3_22415368_ChIP-Seq_MEFs_Mouse1.12567756
82THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11198671
83ESR1_21235772_ChIP-Seq_MCF-7_Human1.09150652
84* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08373908
85SMAD_19615063_ChIP-ChIP_OVARY_Human1.08144720
86RACK7_27058665_Chip-Seq_MCF-7_Human1.08051932
87* E2F1_21310950_ChIP-Seq_MCF-7_Human1.07463549
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07062578
89SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.07015276
90KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06925729
91MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.06583259
92BP1_19119308_ChIP-ChIP_Hs578T_Human1.05466059
93TTF2_22483619_ChIP-Seq_HELA_Human1.03193335
94ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02717474
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02026086
96ETS1_20019798_ChIP-Seq_JURKAT_Human1.00520328
97PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00309444
98WT1_19549856_ChIP-ChIP_CCG9911_Human0.99604844
99UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99534958
100* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.98631309
101EST1_17652178_ChIP-ChIP_JURKAT_Human0.98249708
102KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98135312
103NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97941245
104P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97277716
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97075406
106CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.96561269
107MYCN_18555785_ChIP-Seq_MESCs_Mouse0.96233006
108SA1_22415368_ChIP-Seq_MEFs_Mouse0.96129772
109KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.96070822
110* TP53_23651856_ChIP-Seq_MEFs_Mouse0.95976361
111TET1_21451524_ChIP-Seq_MESCs_Mouse0.95105286
112SOX17_20123909_ChIP-Seq_XEN_Mouse0.93683056
113KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93612381
114EP300_21415370_ChIP-Seq_HL-1_Mouse0.93478891
115TBX5_21415370_ChIP-Seq_HL-1_Mouse0.92724895
116* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.91972386
117SMC1_22415368_ChIP-Seq_MEFs_Mouse0.91931421
118DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91420130
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.90297382
120KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.90047118
121KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.90047118
122KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.90047118
123ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.89769562
124SOX2_18692474_ChIP-Seq_MEFs_Mouse0.89463715
125OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89323114
126CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.89232651
127JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.87983084
128TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.87876336

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.13177578
2MP0003705_abnormal_hypodermis_morpholog3.96616383
3MP0005275_abnormal_skin_tensile3.04416196
4MP0005503_abnormal_tendon_morphology2.95306789
5MP0003279_aneurysm2.90447725
6MP0003566_abnormal_cell_adhesion2.66073254
7MP0010030_abnormal_orbit_morphology2.65003956
8MP0010352_gastrointestinal_tract_polyps2.56827575
9MP0004272_abnormal_basement_membrane2.50083298
10MP0005023_abnormal_wound_healing2.33436861
11MP0005623_abnormal_meninges_morphology2.32765697
12MP0000751_myopathy2.04201031
13MP0003091_abnormal_cell_migration2.00475995
14MP0010368_abnormal_lymphatic_system1.99462077
15MP0000733_abnormal_muscle_development1.96775042
16MP0000750_abnormal_muscle_regeneration1.93831795
17MP0006054_spinal_hemorrhage1.86244148
18MP0005257_abnormal_intraocular_pressure1.72748174
19MP0001958_emphysema1.72512706
20MP0002877_abnormal_melanocyte_morpholog1.62390002
21MP0008007_abnormal_cellular_replicative1.62036841
22MP0009053_abnormal_anal_canal1.61685723
23MP0001542_abnormal_bone_strength1.59911978
24MP0005508_abnormal_skeleton_morphology1.57000023
25MP0000762_abnormal_tongue_morphology1.55792748
26MP0005076_abnormal_cell_differentiation1.50981415
27MP0000767_abnormal_smooth_muscle1.49949030
28MP0004233_abnormal_muscle_weight1.49088169
29MP0003693_abnormal_embryo_hatching1.45270689
30MP0000013_abnormal_adipose_tissue1.44718506
31MP0000858_altered_metastatic_potential1.43892352
32MP0009384_cardiac_valve_regurgitation1.41430878
33MP0001879_abnormal_lymphatic_vessel1.40228976
34MP0002295_abnormal_pulmonary_circulatio1.38842906
35MP0002060_abnormal_skin_morphology1.37853663
36MP0001243_abnormal_dermal_layer1.36141680
37MP0003950_abnormal_plasma_membrane1.35788093
38MP0003385_abnormal_body_wall1.31109590
39MP0003077_abnormal_cell_cycle1.30182356
40MP0004957_abnormal_blastocyst_morpholog1.28728369
41MP0003941_abnormal_skin_development1.28590262
42MP0003191_abnormal_cellular_cholesterol1.28567312
43MP0005595_abnormal_vascular_smooth1.25816130
44MP0010307_abnormal_tumor_latency1.24521893
45MP0004858_abnormal_nervous_system1.23823886
46MP0001915_intracranial_hemorrhage1.23328492
47MP0008932_abnormal_embryonic_tissue1.22313823
48MP0000343_altered_response_to1.21595090
49MP0005390_skeleton_phenotype1.20956582
50MP0003448_altered_tumor_morphology1.19745778
51MP0000579_abnormal_nail_morphology1.14492484
52MP0003111_abnormal_nucleus_morphology1.14384982
53MP0005058_abnormal_lysosome_morphology1.13633117
54MP0002282_abnormal_trachea_morphology1.13276014
55MP0000467_abnormal_esophagus_morphology1.12189337
56MP0009250_abnormal_appendicular_skeleto1.12088123
57MP0001533_abnormal_skeleton_physiology1.10998351
58MP0003436_decreased_susceptibility_to1.10766415
59MP0000516_abnormal_urinary_system1.07667137
60MP0005367_renal/urinary_system_phenotyp1.07667137
61MP0005501_abnormal_skin_physiology1.06911385
62MP0000003_abnormal_adipose_tissue1.06768558
63MP0000749_muscle_degeneration1.04664269
64MP0000350_abnormal_cell_proliferation1.04337093
65MP0001730_embryonic_growth_arrest1.04175910
66MP0009840_abnormal_foam_cell1.03778727
67MP0002796_impaired_skin_barrier0.99306662
68MP0003453_abnormal_keratinocyte_physiol0.99247857
69MP0005197_abnormal_uvea_morphology0.98023100
70MP0005165_increased_susceptibility_to0.97226429
71MP0001614_abnormal_blood_vessel0.97206993
72MP0005330_cardiomyopathy0.96380654
73MP0004197_abnormal_fetal_growth/weight/0.95948425
74MP0000537_abnormal_urethra_morphology0.95859135
75MP0001348_abnormal_lacrimal_gland0.94668827
76MP0004808_abnormal_hematopoietic_stem0.93467207
77MP0002933_joint_inflammation0.93240072
78MP0002932_abnormal_joint_morphology0.92529111
79MP0000163_abnormal_cartilage_morphology0.92434039
80MP0003942_abnormal_urinary_system0.92376265
81MP0002896_abnormal_bone_mineralization0.91920099
82MP0003755_abnormal_palate_morphology0.91665403
83MP0002113_abnormal_skeleton_development0.89792295
84MP0001672_abnormal_embryogenesis/_devel0.88895068
85MP0005380_embryogenesis_phenotype0.88895068
86MP0003984_embryonic_growth_retardation0.88682483
87MP0001697_abnormal_embryo_size0.87826683
88MP0000747_muscle_weakness0.87462416
89MP0001216_abnormal_epidermal_layer0.87357744
90MP0002925_abnormal_cardiovascular_devel0.87099048
91MP0002088_abnormal_embryonic_growth/wei0.86769458
92MP0002128_abnormal_blood_circulation0.85681090
93MP0009333_abnormal_splenocyte_physiolog0.84531857
94MP0001299_abnormal_eye_distance/0.84052087
95MP0000534_abnormal_ureter_morphology0.83921310
96MP0010094_abnormal_chromosome_stability0.83708195
97MP0002086_abnormal_extraembryonic_tissu0.83009804
98MP0005409_darkened_coat_color0.81604926
99MP0002111_abnormal_tail_morphology0.81549702
100MP0009780_abnormal_chondrocyte_physiolo0.81099710
101MP0005193_abnormal_anterior_eye0.80891224
102MP0002269_muscular_atrophy0.78169856
103MP0004087_abnormal_muscle_fiber0.78035145
104MP0003828_pulmonary_edema0.77254949
105MP0002115_abnormal_skeleton_extremities0.76777887
106MP0000428_abnormal_craniofacial_morphol0.76075017
107MP0001175_abnormal_lung_morphology0.75906272
108MP0004084_abnormal_cardiac_muscle0.75879525
109MP0002085_abnormal_embryonic_tissue0.75688715
110MP0005164_abnormal_response_to0.75234007
111MP0001661_extended_life_span0.75148647
112MP0000432_abnormal_head_morphology0.74762367
113MP0003115_abnormal_respiratory_system0.74673158
114MP0010771_integument_phenotype0.74193320
115MP0006138_congestive_heart_failure0.74041604
116MP0005621_abnormal_cell_physiology0.73402782
117MP0008260_abnormal_autophagy0.73045835
118MP0003718_maternal_effect0.71758809
119MP0000759_abnormal_skeletal_muscle0.71286531
120MP0003303_peritoneal_inflammation0.70647808
121MP0003937_abnormal_limbs/digits/tail_de0.70559270
122MP0003300_gastrointestinal_ulcer0.69624544
123MP0000249_abnormal_blood_vessel0.69425722
124MP0010630_abnormal_cardiac_muscle0.68731651
125MP0005395_other_phenotype0.68470099
126MP0000049_abnormal_middle_ear0.68427829
127MP0002108_abnormal_muscle_morphology0.68131346
128MP0001849_ear_inflammation0.68103673
129MP0002084_abnormal_developmental_patter0.67645675
130MP0003123_paternal_imprinting0.67275041
131MP0004510_myositis0.67192243
132MP0002972_abnormal_cardiac_muscle0.65999091
133MP0004036_abnormal_muscle_relaxation0.63869303
134MP0002177_abnormal_outer_ear0.62706038
135MP0005620_abnormal_muscle_contractility0.62449734
136MP0003186_abnormal_redox_activity0.62187000
137MP0010234_abnormal_vibrissa_follicle0.60936026
138MP0000678_abnormal_parathyroid_gland0.58769420

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.37596800
2Premature rupture of membranes (HP:0001788)6.20387692
3Cervical subluxation (HP:0003308)3.80211551
4Vertebral compression fractures (HP:0002953)3.76734841
5Shallow orbits (HP:0000586)3.70469206
6Aortic dissection (HP:0002647)3.61514301
7Peritonitis (HP:0002586)3.55384270
8Increased connective tissue (HP:0009025)3.53464469
9Spinal rigidity (HP:0003306)3.47025940
10Cerebral aneurysm (HP:0004944)3.36468648
11Ankle contracture (HP:0006466)3.34302290
12Soft skin (HP:0000977)3.29010997
13Aortic aneurysm (HP:0004942)3.26003257
14Abnormality of the calcaneus (HP:0008364)3.14299378
15Type 1 muscle fiber predominance (HP:0003803)3.12717181
16Atrophic scars (HP:0001075)3.12692334
17Abnormality of dentin (HP:0010299)3.11089258
18Dilatation of the ascending aorta (HP:0005111)3.08522479
19Wormian bones (HP:0002645)3.04583989
20Short nail (HP:0001799)2.99775725
21Wrist flexion contracture (HP:0001239)2.97643684
22Biconcave vertebral bodies (HP:0004586)2.96294164
23Difficulty climbing stairs (HP:0003551)2.79899840
24Osteolytic defects of the phalanges of the hand (HP:0009771)2.79707531
25Osteolytic defects of the hand bones (HP:0009699)2.79707531
26Increased density of long bones (HP:0006392)2.73070058
27Trismus (HP:0000211)2.70015215
28Blue sclerae (HP:0000592)2.64257293
29Calcaneovalgus deformity (HP:0001848)2.61631144
30Spondylolisthesis (HP:0003302)2.61538741
31Fragile skin (HP:0001030)2.58874132
32Fused cervical vertebrae (HP:0002949)2.58730145
33Genu recurvatum (HP:0002816)2.53863467
34Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.53421997
35Popliteal pterygium (HP:0009756)2.49389410
36Round ear (HP:0100830)2.49218109
37Achilles tendon contracture (HP:0001771)2.48761669
38Distal lower limb muscle weakness (HP:0009053)2.45198987
39Reduced subcutaneous adipose tissue (HP:0003758)2.43642226
40Ulnar deviation of the wrist (HP:0003049)2.43327478
41Bladder diverticulum (HP:0000015)2.39992278
42Abnormality of the acetabulum (HP:0003170)2.39949394
43Distal lower limb amyotrophy (HP:0008944)2.39402441
44Abnormality of placental membranes (HP:0011409)2.37254739
45Amniotic constriction ring (HP:0009775)2.37254739
46Increased variability in muscle fiber diameter (HP:0003557)2.36602013
47Mitral regurgitation (HP:0001653)2.34517075
48Scapular winging (HP:0003691)2.34159177
49Deformed tarsal bones (HP:0008119)2.34141425
50Muscle fiber inclusion bodies (HP:0100299)2.31142800
51Breech presentation (HP:0001623)2.30372125
52Neonatal short-limb short stature (HP:0008921)2.25517307
53Nemaline bodies (HP:0003798)2.22125457
54Selective tooth agenesis (HP:0001592)2.21091066
55Distal arthrogryposis (HP:0005684)2.18627264
56Abnormal delivery (HP:0001787)2.17542163
57Aortic regurgitation (HP:0001659)2.13134460
58Coxa vara (HP:0002812)2.11768654
59Entropion (HP:0000621)2.11450973
60Mesomelia (HP:0003027)2.10948992
61Mildly elevated creatine phosphokinase (HP:0008180)2.10754748
62Elbow flexion contracture (HP:0002987)2.09711856
63Mitral valve prolapse (HP:0001634)2.09684930
64Abnormalities of placenta or umbilical cord (HP:0001194)2.09539050
65Upper limb amyotrophy (HP:0009129)2.08793355
66Distal upper limb amyotrophy (HP:0007149)2.08793355
67Abnormality of the Achilles tendon (HP:0005109)2.08705170
68Camptodactyly of toe (HP:0001836)2.05401207
69Disproportionate tall stature (HP:0001519)2.01971274
70Vascular tortuosity (HP:0004948)2.01414220
71Bowel diverticulosis (HP:0005222)1.97636432
72Syringomyelia (HP:0003396)1.94712764
73Spinal cord lesions (HP:0100561)1.94712764
74Pterygium (HP:0001059)1.92946684
75Cardiovascular calcification (HP:0011915)1.92855633
76Radial bowing (HP:0002986)1.92815246
77Nonimmune hydrops fetalis (HP:0001790)1.92574242
78Abnormality of the distal phalanges of the toes (HP:0010182)1.92569453
79Muscle fiber splitting (HP:0003555)1.92288224
80Aortic valve stenosis (HP:0001650)1.91766967
81Lower limb amyotrophy (HP:0007210)1.90663515
82Follicular hyperkeratosis (HP:0007502)1.89730384
83Beaking of vertebral bodies (HP:0004568)1.87664301
84Thin ribs (HP:0000883)1.86939655
85Mitral stenosis (HP:0001718)1.86855570
86Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.84420085
87Vertebral hypoplasia (HP:0008417)1.84420085
88Abnormality of the peritoneum (HP:0002585)1.84349444
89Aneurysm (HP:0002617)1.83812797
90Abnormality of the umbilical cord (HP:0010881)1.82869934
91Hyperacusis (HP:0010780)1.81838140
92Right ventricular cardiomyopathy (HP:0011663)1.81752873
93Broad metatarsal (HP:0001783)1.80487664
94Myocardial infarction (HP:0001658)1.80131008
95Flexion contracture of toe (HP:0005830)1.79340356
96Joint contractures involving the joints of the feet (HP:0100492)1.79340356
97Arterial tortuosity (HP:0005116)1.78146744
98Fragile nails (HP:0001808)1.77982366
99Slender long bone (HP:0003100)1.77606711
100Joint stiffness (HP:0001387)1.76954788
101Abnormality of skeletal muscle fiber size (HP:0012084)1.76677529
102Tarsal synostosis (HP:0008368)1.76265173
103Platyspondyly (HP:0000926)1.75992718
104Knee flexion contracture (HP:0006380)1.75733415
105Limb-girdle muscle weakness (HP:0003325)1.74919637
106Ectopia lentis (HP:0001083)1.74377717
107Abnormality of the neuromuscular junction (HP:0003398)1.73255131
108Fatigable weakness (HP:0003473)1.73255131
109Generalized amyotrophy (HP:0003700)1.73064257
110Neck muscle weakness (HP:0000467)1.72621331
111Slender build (HP:0001533)1.71893809
112Natal tooth (HP:0000695)1.70271655
113Abnormality of the proximal phalanges of the hand (HP:0009834)1.68548139
114Ulnar bowing (HP:0003031)1.68303290
115Asymmetric septal hypertrophy (HP:0001670)1.67966120
116Hip contracture (HP:0003273)1.67525700
117Absent phalangeal crease (HP:0006109)1.67497508
118Short 4th metacarpal (HP:0010044)1.67490629
119Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.67490629
120Broad face (HP:0000283)1.67483471
121Aplasia of the musculature (HP:0100854)1.66479626
122Overgrowth (HP:0001548)1.66409149
123Protruding ear (HP:0000411)1.66175728
124Hyperextensible skin (HP:0000974)1.65632077
125Delayed gross motor development (HP:0002194)1.64999581
126Delayed cranial suture closure (HP:0000270)1.63369777
127Hand muscle atrophy (HP:0009130)1.62125450
128Joint laxity (HP:0001388)1.61231323
129Spinal cord compression (HP:0002176)1.60664701
130Limb-girdle muscle atrophy (HP:0003797)1.60353782

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK13.41984242
2TTN3.11317091
3LATS22.97927456
4EPHA22.72165254
5PIM22.64564434
6LIMK12.59490159
7IRAK32.43363557
8TRIB32.40065162
9RPS6KA42.38113898
10BUB12.35724652
11TESK22.33596465
12MOS2.22288923
13NTRK12.02660041
14MAP3K31.91098216
15KDR1.90341583
16DDR21.88636313
17NME21.87677215
18STK101.84935229
19MUSK1.75531411
20ERN11.64449284
21LATS11.63787769
22TIE11.63279132
23ARAF1.59680770
24STK38L1.59667571
25BMX1.56480809
26EIF2AK11.56139199
27PAK41.54123443
28PKN21.53719296
29MAP3K121.52834987
30LRRK21.51919148
31TRPM71.47693716
32PAK21.46110475
33TGFBR11.45557742
34SMG11.42007920
35MAP3K81.36026357
36MST1R1.31750076
37PDGFRA1.31453842
38PTK21.30163820
39PIK3CG1.29728447
40NEK91.25691752
41SIK11.24260697
42PTK61.22638861
43WEE11.21063455
44ERBB31.20914508
45EPHB21.19430583
46PLK41.11956888
47ZAK1.11548133
48MAPKAPK31.11272180
49TTK1.10297804
50NEK11.09091657
51RPS6KB21.08924435
52STK31.08310301
53PAK11.01975938
54ILK1.00522662
55MAP3K141.00243508
56MAP3K110.99654942
57TBK10.96890825
58MAP2K30.96237076
59CDC70.93624787
60ROCK20.93108873
61NEK20.92602701
62PAK60.92579287
63PTK2B0.90611282
64MET0.89696859
65ICK0.88242904
66RIPK10.87320764
67CDK120.86873320
68EEF2K0.85992309
69AURKB0.85307451
70ABL20.83950913
71PLK10.81456769
72BRSK20.81293813
73DMPK0.80006585
74ERBB40.78322548
75FER0.78162338
76MAP2K10.77849672
77CDK70.77176825
78VRK20.76474030
79PRKD20.75889968
80CDK60.72754560
81CHUK0.71113540
82MYLK0.70321598
83TAOK20.69646535
84CDC42BPA0.68581389
85PIM10.68458425
86AURKA0.67315089
87ROCK10.65858619
88EIF2AK20.65126997
89MTOR0.64520600
90EIF2AK30.63791351
91JAK30.63787903
92PBK0.63040302
93IKBKB0.62884178
94BRSK10.62239634
95TGFBR20.61973322
96CLK10.61972975
97PLK30.59819349
98PDGFRB0.59114751
99DAPK30.58445916
100FGFR10.58076709
101RPS6KA20.58007619
102MAPKAPK20.57310305
103SCYL20.57067342
104MAP3K60.57031582
105LMTK20.56294372
106GRK70.56247379
107STK380.56029738
108PRPF4B0.53748061
109STK40.52092304
110PRKG20.48948120
111CCNB10.48340481
112KSR20.47969185
113GSK3A0.47553143
114MELK0.47435823
115CAMK2G0.46110117
116PIK3CA0.45439633
117CDK90.45216602
118ACVR1B0.44269702
119MKNK10.43971368
120CDK80.42062457
121MAP3K50.42040686
122BRAF0.41897721
123MAP3K100.41570778
124PAK30.37751229
125FLT30.36890674
126CHEK20.36541307
127CDK140.36264418
128EPHB10.35705472
129CDK150.34702024
130PDK20.34052340
131AKT20.33826238
132CDK40.32995507

Predicted pathways (KEGG)

RankGene SetZ-score
1p53 signaling pathway_Homo sapiens_hsa041152.37920517
2Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005342.30874225
3Proteasome_Homo sapiens_hsa030502.30461854
4ECM-receptor interaction_Homo sapiens_hsa045122.24482507
5Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.09598509
6Shigellosis_Homo sapiens_hsa051311.99041225
7Focal adhesion_Homo sapiens_hsa045101.96331332
8Cell cycle_Homo sapiens_hsa041101.93042754
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.87373303
10* Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.86198353
11Malaria_Homo sapiens_hsa051441.85484732
12Adherens junction_Homo sapiens_hsa045201.81789653
13Proteoglycans in cancer_Homo sapiens_hsa052051.80768047
14Small cell lung cancer_Homo sapiens_hsa052221.78070687
15TGF-beta signaling pathway_Homo sapiens_hsa043501.77518185
16Bladder cancer_Homo sapiens_hsa052191.77048392
17Viral myocarditis_Homo sapiens_hsa054161.76689236
18Legionellosis_Homo sapiens_hsa051341.72132585
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.70758628
20RNA transport_Homo sapiens_hsa030131.67389284
21MicroRNAs in cancer_Homo sapiens_hsa052061.66239311
22DNA replication_Homo sapiens_hsa030301.65560056
23Galactose metabolism_Homo sapiens_hsa000521.58523840
24One carbon pool by folate_Homo sapiens_hsa006701.58253558
25Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.57340460
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.54159529
27Hippo signaling pathway_Homo sapiens_hsa043901.53658917
28Apoptosis_Homo sapiens_hsa042101.51078386
29AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.42733588
30TNF signaling pathway_Homo sapiens_hsa046681.41709045
31Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.40062796
32Leishmaniasis_Homo sapiens_hsa051401.39515361
33Amoebiasis_Homo sapiens_hsa051461.37985358
34Pentose phosphate pathway_Homo sapiens_hsa000301.32033884
35Viral carcinogenesis_Homo sapiens_hsa052031.30058601
36Salmonella infection_Homo sapiens_hsa051321.26595731
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.26427727
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.25523670
39HTLV-I infection_Homo sapiens_hsa051661.23909362
40Dilated cardiomyopathy_Homo sapiens_hsa054141.23532163
41Chronic myeloid leukemia_Homo sapiens_hsa052201.16401021
42Mismatch repair_Homo sapiens_hsa034301.16327645
43Vibrio cholerae infection_Homo sapiens_hsa051101.16112794
44Biosynthesis of amino acids_Homo sapiens_hsa012301.15840960
45Epstein-Barr virus infection_Homo sapiens_hsa051691.15802003
46Regulation of actin cytoskeleton_Homo sapiens_hsa048101.13526841
47Pertussis_Homo sapiens_hsa051331.11971465
48Nucleotide excision repair_Homo sapiens_hsa034201.11386287
492-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.09870209
50Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.09532378
51Toxoplasmosis_Homo sapiens_hsa051451.08644222
52Sulfur metabolism_Homo sapiens_hsa009201.08350696
53Base excision repair_Homo sapiens_hsa034101.08297927
54HIF-1 signaling pathway_Homo sapiens_hsa040661.06202544
55N-Glycan biosynthesis_Homo sapiens_hsa005101.05452367
56Sulfur relay system_Homo sapiens_hsa041221.05069471
57Hepatitis B_Homo sapiens_hsa051611.02246321
58PI3K-Akt signaling pathway_Homo sapiens_hsa041511.01042249
59Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00475574
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.99566323
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.98799041
62Ribosome_Homo sapiens_hsa030100.98624480
63RNA polymerase_Homo sapiens_hsa030200.98261275
64Spliceosome_Homo sapiens_hsa030400.97656389
65Toll-like receptor signaling pathway_Homo sapiens_hsa046200.95487547
66* Phagosome_Homo sapiens_hsa041450.92828468
67Herpes simplex infection_Homo sapiens_hsa051680.89695010
68Tight junction_Homo sapiens_hsa045300.89521845
69Basal cell carcinoma_Homo sapiens_hsa052170.87798344
70Pancreatic cancer_Homo sapiens_hsa052120.87771719
71Glutathione metabolism_Homo sapiens_hsa004800.87281608
72Melanoma_Homo sapiens_hsa052180.86539916
73Folate biosynthesis_Homo sapiens_hsa007900.86081601
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.83373170
75Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.83273007
76Fatty acid elongation_Homo sapiens_hsa000620.82993106
77Antigen processing and presentation_Homo sapiens_hsa046120.82874637
78Pyrimidine metabolism_Homo sapiens_hsa002400.82247547
79Pathways in cancer_Homo sapiens_hsa052000.81020068
80Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.80026990
81Homologous recombination_Homo sapiens_hsa034400.79541888
82Thyroid cancer_Homo sapiens_hsa052160.77538754
83Measles_Homo sapiens_hsa051620.77259484
84Systemic lupus erythematosus_Homo sapiens_hsa053220.76380236
85Influenza A_Homo sapiens_hsa051640.74650459
86Carbon metabolism_Homo sapiens_hsa012000.74002291
87Fructose and mannose metabolism_Homo sapiens_hsa000510.73505241
88Hedgehog signaling pathway_Homo sapiens_hsa043400.72994139
89Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.72151590
90Endocytosis_Homo sapiens_hsa041440.71826056
91Osteoclast differentiation_Homo sapiens_hsa043800.71654300
92Tuberculosis_Homo sapiens_hsa051520.71535159
93Prostate cancer_Homo sapiens_hsa052150.69946406
94RNA degradation_Homo sapiens_hsa030180.69852414
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.68743173
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.66505819
97Renal cell carcinoma_Homo sapiens_hsa052110.66050896
98Rheumatoid arthritis_Homo sapiens_hsa053230.66004153
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64556471
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63809662
101Graft-versus-host disease_Homo sapiens_hsa053320.63114766
102Glioma_Homo sapiens_hsa052140.62792389
103Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62006171
104Pyruvate metabolism_Homo sapiens_hsa006200.60588008
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.58434727
106Colorectal cancer_Homo sapiens_hsa052100.55003900
107Basal transcription factors_Homo sapiens_hsa030220.54184837
108Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54112100
109Protein digestion and absorption_Homo sapiens_hsa049740.53940944
110Rap1 signaling pathway_Homo sapiens_hsa040150.53506298
111Allograft rejection_Homo sapiens_hsa053300.53131761
112Platelet activation_Homo sapiens_hsa046110.53005771
113Sphingolipid metabolism_Homo sapiens_hsa006000.51523895
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.51334796
115Hematopoietic cell lineage_Homo sapiens_hsa046400.51155838
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.49259694
117Notch signaling pathway_Homo sapiens_hsa043300.48944742
118Melanogenesis_Homo sapiens_hsa049160.48487612
119Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.48277273
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.47955880
121Other glycan degradation_Homo sapiens_hsa005110.45892497
122Prion diseases_Homo sapiens_hsa050200.45398249
123VEGF signaling pathway_Homo sapiens_hsa043700.45065591
124Lysosome_Homo sapiens_hsa041420.44781031
125Vitamin B6 metabolism_Homo sapiens_hsa007500.44712471
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.44709773
127Axon guidance_Homo sapiens_hsa043600.43986258
128Wnt signaling pathway_Homo sapiens_hsa043100.41759902
129Acute myeloid leukemia_Homo sapiens_hsa052210.41665460
130* Gap junction_Homo sapiens_hsa045400.41662897
131Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36998923
132Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.35543754
133Endometrial cancer_Homo sapiens_hsa052130.32378023
134Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32255364
135Phospholipase D signaling pathway_Homo sapiens_hsa040720.31107643

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »