

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein localization to kinetochore (GO:0034501) | 5.53265771 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.45028798 |
| 3 | DNA double-strand break processing (GO:0000729) | 5.10109553 |
| 4 | chromatin remodeling at centromere (GO:0031055) | 4.98407593 |
| 5 | CENP-A containing nucleosome assembly (GO:0034080) | 4.95653587 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.85206554 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.74611187 |
| 8 | mitotic metaphase plate congression (GO:0007080) | 4.50932943 |
| 9 | protein localization to chromosome, centromeric region (GO:0071459) | 4.50075858 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.43125188 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 4.43125188 |
| 12 | metaphase plate congression (GO:0051310) | 4.41380233 |
| 13 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.40431161 |
| 14 | chaperone-mediated protein transport (GO:0072321) | 4.31518969 |
| 15 | protein K6-linked ubiquitination (GO:0085020) | 4.28136143 |
| 16 | mitotic sister chromatid segregation (GO:0000070) | 4.24387000 |
| 17 | cullin deneddylation (GO:0010388) | 4.20784112 |
| 18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.17924647 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.17924647 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.17924647 |
| 21 | microtubule depolymerization (GO:0007019) | 4.13080437 |
| 22 | protein deneddylation (GO:0000338) | 4.08585006 |
| 23 | histone exchange (GO:0043486) | 4.00945777 |
| 24 | sister chromatid segregation (GO:0000819) | 3.90994135 |
| 25 | establishment of chromosome localization (GO:0051303) | 3.83808869 |
| 26 | protein-cofactor linkage (GO:0018065) | 3.76765905 |
| 27 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.75577431 |
| 28 | DNA replication-independent nucleosome organization (GO:0034724) | 3.75577431 |
| 29 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.71744406 |
| 30 | regulation of DNA endoreduplication (GO:0032875) | 3.70837152 |
| 31 | DNA replication checkpoint (GO:0000076) | 3.70562079 |
| 32 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.69161422 |
| 33 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.69016729 |
| 34 | protein complex biogenesis (GO:0070271) | 3.68340368 |
| 35 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.67681329 |
| 36 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.60443578 |
| 37 | protein neddylation (GO:0045116) | 3.60414569 |
| 38 | protein localization to chromosome (GO:0034502) | 3.59461660 |
| 39 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.59338221 |
| 40 | spindle checkpoint (GO:0031577) | 3.58800669 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.53280185 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.51099900 |
| 43 | sequestering of actin monomers (GO:0042989) | 3.50318820 |
| 44 | organelle disassembly (GO:1903008) | 3.50050131 |
| 45 | DNA strand renaturation (GO:0000733) | 3.46364879 |
| 46 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.45394159 |
| 47 | maturation of 5.8S rRNA (GO:0000460) | 3.41905263 |
| 48 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.38878367 |
| 49 | replication fork processing (GO:0031297) | 3.37338541 |
| 50 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.33110059 |
| 51 | DNA ligation (GO:0006266) | 3.31578466 |
| 52 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.27530213 |
| 53 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22463837 |
| 54 | negative regulation of ligase activity (GO:0051352) | 3.22463837 |
| 55 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.21091091 |
| 56 | mitotic spindle checkpoint (GO:0071174) | 3.19512867 |
| 57 | proteasome assembly (GO:0043248) | 3.17864317 |
| 58 | resolution of meiotic recombination intermediates (GO:0000712) | 3.09591145 |
| 59 | DNA deamination (GO:0045006) | 3.08632084 |
| 60 | postreplication repair (GO:0006301) | 3.08261562 |
| 61 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.06908620 |
| 62 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.06908620 |
| 63 | DNA strand elongation (GO:0022616) | 3.02505599 |
| 64 | rRNA modification (GO:0000154) | 3.02490857 |
| 65 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.01213331 |
| 66 | respiratory electron transport chain (GO:0022904) | 2.99186028 |
| 67 | telomere maintenance via recombination (GO:0000722) | 2.98678343 |
| 68 | negative regulation of chromosome segregation (GO:0051985) | 2.98436048 |
| 69 | telomere maintenance via telomere lengthening (GO:0010833) | 2.98144697 |
| 70 | ribosome assembly (GO:0042255) | 2.97637288 |
| 71 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.96821995 |
| 72 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.96821995 |
| 73 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.96821995 |
| 74 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.96821995 |
| 75 | negative regulation of sister chromatid segregation (GO:0033046) | 2.96821995 |
| 76 | termination of RNA polymerase I transcription (GO:0006363) | 2.96816564 |
| 77 | microtubule polymerization or depolymerization (GO:0031109) | 2.96315351 |
| 78 | mitotic recombination (GO:0006312) | 2.95600618 |
| 79 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.93244173 |
| 80 | ribonucleoprotein complex disassembly (GO:0032988) | 2.93165025 |
| 81 | meiotic chromosome segregation (GO:0045132) | 2.91669463 |
| 82 | electron transport chain (GO:0022900) | 2.91365403 |
| 83 | regulation of sister chromatid cohesion (GO:0007063) | 2.89837572 |
| 84 | recombinational repair (GO:0000725) | 2.89720598 |
| 85 | spindle assembly checkpoint (GO:0071173) | 2.88438993 |
| 86 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.88415494 |
| 87 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.88415494 |
| 88 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.88415494 |
| 89 | chromosome segregation (GO:0007059) | 2.88085142 |
| 90 | negative regulation of DNA recombination (GO:0045910) | 2.87402595 |
| 91 | regulation of chromosome segregation (GO:0051983) | 2.86489951 |
| 92 | inner mitochondrial membrane organization (GO:0007007) | 2.85856790 |
| 93 | mitotic spindle assembly checkpoint (GO:0007094) | 2.85283006 |
| 94 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.85177013 |
| 95 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.85177013 |
| 96 | double-strand break repair via homologous recombination (GO:0000724) | 2.83938989 |
| 97 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.83284257 |
| 98 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.83284257 |
| 99 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.82984336 |
| 100 | spliceosomal snRNP assembly (GO:0000387) | 2.82583098 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.99520047 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.13081380 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.52131269 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.15783526 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.06680192 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.03180177 |
| 7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.60337138 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.35777183 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.14396874 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.09373168 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79300793 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.60840561 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.60341917 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.51588917 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.47679691 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.46698604 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.45406768 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38644925 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.29401257 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.18843843 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.14450484 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.14330523 |
| 23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.00956744 |
| 24 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.97041713 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.94985362 |
| 26 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.86345046 |
| 27 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.85984886 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84237765 |
| 29 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79489543 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.73723630 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.68573415 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68136115 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.63793136 |
| 34 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.61961531 |
| 35 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.61362086 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.59179293 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.57645457 |
| 38 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.55594807 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.53273735 |
| 40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.53168769 |
| 41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.50739137 |
| 42 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.50426368 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.47009518 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.44261264 |
| 45 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.43491758 |
| 46 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.40921151 |
| 47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.39897730 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.39534233 |
| 49 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.37574666 |
| 50 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.36047174 |
| 51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.35735286 |
| 52 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32042116 |
| 53 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.26358247 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.25794737 |
| 55 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24367393 |
| 56 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.24269881 |
| 57 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.23828682 |
| 58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.22435477 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21328591 |
| 60 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.20703028 |
| 61 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.19893519 |
| 62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.18441070 |
| 63 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.16922841 |
| 64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.16246816 |
| 65 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.10767022 |
| 66 | P300_19829295_ChIP-Seq_ESCs_Human | 1.09038316 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.06698097 |
| 68 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.05364120 |
| 69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.04821100 |
| 70 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03458373 |
| 71 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.03385840 |
| 72 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.01888196 |
| 73 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.00868932 |
| 74 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.97927368 |
| 75 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.97655878 |
| 76 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96000872 |
| 77 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.94554991 |
| 78 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.88624921 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.87478531 |
| 80 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.87042569 |
| 81 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.85819076 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.84417525 |
| 83 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.82951197 |
| 84 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.82525859 |
| 85 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.82525859 |
| 86 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.81497368 |
| 87 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.80371596 |
| 88 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.78607423 |
| 89 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.77917509 |
| 90 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.77547669 |
| 91 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.75365431 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 0.75319584 |
| 93 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.73763356 |
| 94 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.73613977 |
| 95 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.73201532 |
| 96 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.72929921 |
| 97 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.70365302 |
| 98 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.70048118 |
| 99 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.69991454 |
| 100 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.69716910 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 4.27015944 |
| 2 | MP0003693_abnormal_embryo_hatching | 4.26518036 |
| 3 | MP0010094_abnormal_chromosome_stability | 3.90067169 |
| 4 | MP0008058_abnormal_DNA_repair | 3.30986884 |
| 5 | MP0004957_abnormal_blastocyst_morpholog | 3.16953892 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.92476630 |
| 7 | MP0002653_abnormal_ependyma_morphology | 2.88034491 |
| 8 | MP0001529_abnormal_vocalization | 2.60971408 |
| 9 | MP0003077_abnormal_cell_cycle | 2.51201523 |
| 10 | MP0003718_maternal_effect | 2.50899492 |
| 11 | MP0001346_abnormal_lacrimal_gland | 2.42676101 |
| 12 | MP0008995_early_reproductive_senescence | 2.35635229 |
| 13 | MP0001188_hyperpigmentation | 2.30719245 |
| 14 | MP0008057_abnormal_DNA_replication | 2.29544111 |
| 15 | MP0008932_abnormal_embryonic_tissue | 2.29222015 |
| 16 | MP0004133_heterotaxia | 2.28678259 |
| 17 | MP0005084_abnormal_gallbladder_morpholo | 2.27101205 |
| 18 | MP0003111_abnormal_nucleus_morphology | 2.17022757 |
| 19 | MP0008877_abnormal_DNA_methylation | 2.16072483 |
| 20 | MP0006292_abnormal_olfactory_placode | 2.15460767 |
| 21 | MP0005253_abnormal_eye_physiology | 2.03711123 |
| 22 | MP0003011_delayed_dark_adaptation | 2.02192928 |
| 23 | MP0006035_abnormal_mitochondrial_morpho | 1.82295778 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.81320929 |
| 25 | MP0003786_premature_aging | 1.76678213 |
| 26 | MP0005248_abnormal_Harderian_gland | 1.52691371 |
| 27 | MP0002138_abnormal_hepatobiliary_system | 1.48152599 |
| 28 | MP0004147_increased_porphyrin_level | 1.47370097 |
| 29 | MP0005394_taste/olfaction_phenotype | 1.44913198 |
| 30 | MP0005499_abnormal_olfactory_system | 1.44913198 |
| 31 | MP0006036_abnormal_mitochondrial_physio | 1.44735212 |
| 32 | MP0001984_abnormal_olfaction | 1.44490034 |
| 33 | MP0000631_abnormal_neuroendocrine_gland | 1.43569708 |
| 34 | MP0003121_genomic_imprinting | 1.42332298 |
| 35 | MP0008007_abnormal_cellular_replicative | 1.34518865 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.33067893 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.27810685 |
| 38 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25388658 |
| 39 | MP0000372_irregular_coat_pigmentation | 1.24365365 |
| 40 | MP0009697_abnormal_copulation | 1.23187276 |
| 41 | MP0002277_abnormal_respiratory_mucosa | 1.20863438 |
| 42 | MP0002210_abnormal_sex_determination | 1.19037044 |
| 43 | MP0003122_maternal_imprinting | 1.15582800 |
| 44 | MP0001929_abnormal_gametogenesis | 1.15060654 |
| 45 | MP0005167_abnormal_blood-brain_barrier | 1.15033420 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 1.14214009 |
| 47 | MP0002938_white_spotting | 1.09886960 |
| 48 | MP0003880_abnormal_central_pattern | 1.08973949 |
| 49 | MP0004145_abnormal_muscle_electrophysio | 1.08413479 |
| 50 | MP0003195_calcinosis | 1.08158744 |
| 51 | MP0002234_abnormal_pharynx_morphology | 1.07927863 |
| 52 | MP0002233_abnormal_nose_morphology | 1.06537269 |
| 53 | MP0002928_abnormal_bile_duct | 1.06524349 |
| 54 | MP0000049_abnormal_middle_ear | 1.06333856 |
| 55 | MP0001486_abnormal_startle_reflex | 1.06192915 |
| 56 | MP0001286_abnormal_eye_development | 1.04776055 |
| 57 | MP0001697_abnormal_embryo_size | 0.98691607 |
| 58 | MP0000026_abnormal_inner_ear | 0.98346300 |
| 59 | MP0002736_abnormal_nociception_after | 0.98109639 |
| 60 | MP0003937_abnormal_limbs/digits/tail_de | 0.98077487 |
| 61 | MP0004215_abnormal_myocardial_fiber | 0.97408330 |
| 62 | MP0000653_abnormal_sex_gland | 0.96077692 |
| 63 | MP0003186_abnormal_redox_activity | 0.95863831 |
| 64 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95548585 |
| 65 | MP0001919_abnormal_reproductive_system | 0.94242447 |
| 66 | MP0002751_abnormal_autonomic_nervous | 0.93604874 |
| 67 | MP0005391_vision/eye_phenotype | 0.92660171 |
| 68 | MP0001293_anophthalmia | 0.92503464 |
| 69 | MP0003646_muscle_fatigue | 0.92025061 |
| 70 | MP0000566_synostosis | 0.90998729 |
| 71 | MP0001145_abnormal_male_reproductive | 0.90245067 |
| 72 | MP0000647_abnormal_sebaceous_gland | 0.89894028 |
| 73 | MP0003938_abnormal_ear_development | 0.89770265 |
| 74 | MP0001119_abnormal_female_reproductive | 0.89711604 |
| 75 | MP0004084_abnormal_cardiac_muscle | 0.87922819 |
| 76 | MP0009745_abnormal_behavioral_response | 0.87391789 |
| 77 | MP0001764_abnormal_homeostasis | 0.86583937 |
| 78 | MP0002272_abnormal_nervous_system | 0.83925098 |
| 79 | MP0006054_spinal_hemorrhage | 0.83246200 |
| 80 | MP0000778_abnormal_nervous_system | 0.80196081 |
| 81 | MP0003119_abnormal_digestive_system | 0.77914242 |
| 82 | MP0003787_abnormal_imprinting | 0.77316383 |
| 83 | MP0001324_abnormal_eye_pigmentation | 0.76876766 |
| 84 | MP0010030_abnormal_orbit_morphology | 0.75068923 |
| 85 | MP0005195_abnormal_posterior_eye | 0.74606925 |
| 86 | MP0005389_reproductive_system_phenotype | 0.74016294 |
| 87 | MP0002752_abnormal_somatic_nervous | 0.73200629 |
| 88 | MP0003698_abnormal_male_reproductive | 0.72489891 |
| 89 | MP0004885_abnormal_endolymph | 0.71390786 |
| 90 | MP0001879_abnormal_lymphatic_vessel | 0.71014090 |
| 91 | MP0002085_abnormal_embryonic_tissue | 0.70597959 |
| 92 | MP0005380_embryogenesis_phenotype | 0.68148939 |
| 93 | MP0001672_abnormal_embryogenesis/_devel | 0.68148939 |
| 94 | MP0001727_abnormal_embryo_implantation | 0.67727012 |
| 95 | MP0001963_abnormal_hearing_physiology | 0.67478363 |
| 96 | MP0005408_hypopigmentation | 0.67343764 |
| 97 | MP0004142_abnormal_muscle_tone | 0.64546834 |
| 98 | MP0002638_abnormal_pupillary_reflex | 0.64010391 |
| 99 | MP0002697_abnormal_eye_size | 0.63590316 |
| 100 | MP0004043_abnormal_pH_regulation | 0.63215926 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.76469036 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.98446889 |
| 3 | Progressive macrocephaly (HP:0004481) | 3.87776360 |
| 4 | Acute encephalopathy (HP:0006846) | 3.86478426 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.69109797 |
| 6 | Supernumerary spleens (HP:0009799) | 3.46592793 |
| 7 | Increased CSF lactate (HP:0002490) | 3.45911682 |
| 8 | Abnormality of the labia minora (HP:0012880) | 3.30966165 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.30813050 |
| 10 | Cerebral edema (HP:0002181) | 3.15164233 |
| 11 | Abnormal lung lobation (HP:0002101) | 3.14406356 |
| 12 | Hepatic necrosis (HP:0002605) | 2.92097017 |
| 13 | Cortical dysplasia (HP:0002539) | 2.83835608 |
| 14 | Colon cancer (HP:0003003) | 2.77744357 |
| 15 | True hermaphroditism (HP:0010459) | 2.76043545 |
| 16 | Increased serum pyruvate (HP:0003542) | 2.73693732 |
| 17 | Adrenal hypoplasia (HP:0000835) | 2.64325413 |
| 18 | Oligodactyly (hands) (HP:0001180) | 2.62756801 |
| 19 | Meckel diverticulum (HP:0002245) | 2.57917447 |
| 20 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.57909590 |
| 21 | Small intestinal stenosis (HP:0012848) | 2.51461588 |
| 22 | Duodenal stenosis (HP:0100867) | 2.51461588 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.47134088 |
| 24 | Abnormality of the ileum (HP:0001549) | 2.46554170 |
| 25 | Abnormality of chromosome stability (HP:0003220) | 2.39133074 |
| 26 | Hypoplasia of the pons (HP:0012110) | 2.37746211 |
| 27 | Abnormality of the preputium (HP:0100587) | 2.36681660 |
| 28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.36153975 |
| 29 | Optic disc pallor (HP:0000543) | 2.32708500 |
| 30 | Increased serum lactate (HP:0002151) | 2.31689204 |
| 31 | Absent/shortened dynein arms (HP:0200106) | 2.31508448 |
| 32 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.31508448 |
| 33 | Abnormality of the duodenum (HP:0002246) | 2.30163673 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.30108800 |
| 35 | Molar tooth sign on MRI (HP:0002419) | 2.30108800 |
| 36 | Abnormality of glycolysis (HP:0004366) | 2.28279664 |
| 37 | Respiratory failure (HP:0002878) | 2.28270242 |
| 38 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.28118241 |
| 39 | Carpal bone hypoplasia (HP:0001498) | 2.26547133 |
| 40 | Medial flaring of the eyebrow (HP:0010747) | 2.23909786 |
| 41 | Nephronophthisis (HP:0000090) | 2.23290365 |
| 42 | Short tibia (HP:0005736) | 2.22428637 |
| 43 | Abnormality of the pons (HP:0007361) | 2.20984237 |
| 44 | Cerebellar dysplasia (HP:0007033) | 2.20356730 |
| 45 | Clubbing of toes (HP:0100760) | 2.18833756 |
| 46 | Lactic acidosis (HP:0003128) | 2.15390284 |
| 47 | Leukodystrophy (HP:0002415) | 2.14358953 |
| 48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.12550628 |
| 49 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.12550628 |
| 50 | Adactyly (HP:0009776) | 2.09664064 |
| 51 | Reduced antithrombin III activity (HP:0001976) | 2.07134845 |
| 52 | Combined immunodeficiency (HP:0005387) | 2.06120643 |
| 53 | Hemivertebrae (HP:0002937) | 2.05345838 |
| 54 | Type I transferrin isoform profile (HP:0003642) | 2.01840066 |
| 55 | Sloping forehead (HP:0000340) | 2.01145487 |
| 56 | Oligodactyly (HP:0012165) | 1.99526699 |
| 57 | Duplicated collecting system (HP:0000081) | 1.97889857 |
| 58 | Pancreatic cysts (HP:0001737) | 1.97416270 |
| 59 | Parakeratosis (HP:0001036) | 1.97415202 |
| 60 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.97164357 |
| 61 | Pendular nystagmus (HP:0012043) | 1.96265009 |
| 62 | 3-Methylglutaconic aciduria (HP:0003535) | 1.96011102 |
| 63 | Chromsome breakage (HP:0040012) | 1.95574698 |
| 64 | Methylmalonic acidemia (HP:0002912) | 1.94344857 |
| 65 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.94214782 |
| 66 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.94214782 |
| 67 | Abnormal protein glycosylation (HP:0012346) | 1.94214782 |
| 68 | Abnormal glycosylation (HP:0012345) | 1.94214782 |
| 69 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.93288042 |
| 70 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.93288042 |
| 71 | Oral leukoplakia (HP:0002745) | 1.91540992 |
| 72 | Abnormality of the renal medulla (HP:0100957) | 1.89569236 |
| 73 | Pancreatic fibrosis (HP:0100732) | 1.88760507 |
| 74 | Abnormality of the renal collecting system (HP:0004742) | 1.88745666 |
| 75 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.88445702 |
| 76 | Exercise intolerance (HP:0003546) | 1.88119110 |
| 77 | Sclerocornea (HP:0000647) | 1.87838499 |
| 78 | IgG deficiency (HP:0004315) | 1.86417442 |
| 79 | Methylmalonic aciduria (HP:0012120) | 1.83610389 |
| 80 | X-linked dominant inheritance (HP:0001423) | 1.82176904 |
| 81 | Retinal dysplasia (HP:0007973) | 1.81894534 |
| 82 | Congenital, generalized hypertrichosis (HP:0004540) | 1.81109479 |
| 83 | Congenital stationary night blindness (HP:0007642) | 1.80869606 |
| 84 | Horseshoe kidney (HP:0000085) | 1.80833417 |
| 85 | Severe combined immunodeficiency (HP:0004430) | 1.80220932 |
| 86 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.78616553 |
| 87 | Myelodysplasia (HP:0002863) | 1.78088348 |
| 88 | Triphalangeal thumb (HP:0001199) | 1.77922993 |
| 89 | Intestinal atresia (HP:0011100) | 1.77382348 |
| 90 | Ependymoma (HP:0002888) | 1.77168239 |
| 91 | Overlapping toe (HP:0001845) | 1.76220734 |
| 92 | Absent septum pellucidum (HP:0001331) | 1.75354166 |
| 93 | Pancytopenia (HP:0001876) | 1.70517140 |
| 94 | Congenital primary aphakia (HP:0007707) | 1.69115226 |
| 95 | Panhypogammaglobulinemia (HP:0003139) | 1.67405072 |
| 96 | Aplasia involving forearm bones (HP:0009822) | 1.67288132 |
| 97 | Absent forearm bone (HP:0003953) | 1.67288132 |
| 98 | Abnormality of abdominal situs (HP:0011620) | 1.66800825 |
| 99 | Abdominal situs inversus (HP:0003363) | 1.66800825 |
| 100 | Irregular epiphyses (HP:0010582) | 1.66301814 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 3.91021977 |
| 2 | NEK1 | 3.89714163 |
| 3 | EIF2AK1 | 3.57591723 |
| 4 | EIF2AK3 | 3.46601703 |
| 5 | VRK2 | 3.41642434 |
| 6 | PBK | 3.38870464 |
| 7 | TAOK1 | 3.19809378 |
| 8 | TAF1 | 3.03941890 |
| 9 | SRPK1 | 2.70518538 |
| 10 | TSSK6 | 2.53443811 |
| 11 | MST4 | 2.49325471 |
| 12 | PLK4 | 2.41265531 |
| 13 | WNK3 | 2.31857438 |
| 14 | NME1 | 2.26141059 |
| 15 | WEE1 | 2.13897791 |
| 16 | TTK | 1.87430544 |
| 17 | PLK3 | 1.80681774 |
| 18 | MKNK2 | 1.79163988 |
| 19 | CCNB1 | 1.71587632 |
| 20 | DYRK2 | 1.71530886 |
| 21 | NEK2 | 1.71038336 |
| 22 | NUAK1 | 1.64908988 |
| 23 | TRIM28 | 1.63942131 |
| 24 | VRK1 | 1.63799218 |
| 25 | BRSK2 | 1.61819831 |
| 26 | CDC7 | 1.58992423 |
| 27 | MKNK1 | 1.55773590 |
| 28 | ZAK | 1.33470731 |
| 29 | EIF2AK2 | 1.33438354 |
| 30 | PINK1 | 1.32028877 |
| 31 | TXK | 1.22943727 |
| 32 | PLK1 | 1.22911399 |
| 33 | STK16 | 1.16806170 |
| 34 | BCKDK | 1.15309461 |
| 35 | PASK | 1.06588309 |
| 36 | CDK3 | 1.04274135 |
| 37 | RPS6KA4 | 1.03401869 |
| 38 | CDK8 | 1.01896847 |
| 39 | AKT3 | 0.99326405 |
| 40 | MELK | 0.99290351 |
| 41 | CSNK1G3 | 0.97398158 |
| 42 | ADRBK2 | 0.95355482 |
| 43 | AURKB | 0.94616830 |
| 44 | CSNK1G2 | 0.92732859 |
| 45 | DYRK3 | 0.92230802 |
| 46 | MINK1 | 0.88704608 |
| 47 | TNIK | 0.88047541 |
| 48 | BCR | 0.87006815 |
| 49 | CSNK1A1L | 0.85091497 |
| 50 | PDK2 | 0.82007008 |
| 51 | CSNK1G1 | 0.77696670 |
| 52 | BRSK1 | 0.77405397 |
| 53 | ATR | 0.77197316 |
| 54 | CHEK2 | 0.75891981 |
| 55 | MAP4K2 | 0.72218411 |
| 56 | UHMK1 | 0.70391092 |
| 57 | STK11 | 0.66296399 |
| 58 | PLK2 | 0.61426763 |
| 59 | GRK1 | 0.60299465 |
| 60 | MAP3K4 | 0.56647590 |
| 61 | TIE1 | 0.53253339 |
| 62 | NEK9 | 0.50219057 |
| 63 | MAPK13 | 0.44603154 |
| 64 | GRK6 | 0.40311999 |
| 65 | ATM | 0.38813497 |
| 66 | CDK7 | 0.38129796 |
| 67 | CSNK2A1 | 0.36154070 |
| 68 | CHEK1 | 0.35991697 |
| 69 | STK38L | 0.35100581 |
| 70 | TGFBR1 | 0.34144762 |
| 71 | SGK2 | 0.32144567 |
| 72 | PIK3CG | 0.31817578 |
| 73 | KSR1 | 0.30648551 |
| 74 | DAPK1 | 0.29917973 |
| 75 | AURKA | 0.29877808 |
| 76 | CSNK2A2 | 0.29014147 |
| 77 | MARK1 | 0.28975001 |
| 78 | PHKG1 | 0.28885646 |
| 79 | PHKG2 | 0.28885646 |
| 80 | CAMKK2 | 0.27997375 |
| 81 | CDK4 | 0.27919786 |
| 82 | NLK | 0.27696015 |
| 83 | ERBB3 | 0.27180486 |
| 84 | CAMK2A | 0.27088070 |
| 85 | PRKCG | 0.25924929 |
| 86 | BMPR1B | 0.25516346 |
| 87 | CSNK1A1 | 0.25383873 |
| 88 | SGK223 | 0.25302391 |
| 89 | SGK494 | 0.25302391 |
| 90 | TEC | 0.25189793 |
| 91 | STK3 | 0.24355932 |
| 92 | BRAF | 0.23894503 |
| 93 | STK4 | 0.23569194 |
| 94 | CSNK1E | 0.21680763 |
| 95 | CDK14 | 0.19710243 |
| 96 | SIK3 | 0.19181753 |
| 97 | SGK1 | 0.18662616 |
| 98 | ALK | 0.18571500 |
| 99 | TLK1 | 0.17291487 |
| 100 | STK39 | 0.16807530 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.94695603 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.41450273 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.27854657 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.17180097 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.11754622 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.07905793 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.76653599 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.76016965 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.71730108 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.52418874 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.41398663 |
| 12 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.25629868 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.20576874 |
| 14 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.20366507 |
| 15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.16172852 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 2.16076141 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 2.15587694 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 2.07705830 |
| 19 | Ribosome_Homo sapiens_hsa03010 | 1.94434963 |
| 20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.94038916 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.92585559 |
| 22 | Cell cycle_Homo sapiens_hsa04110 | 1.92547646 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.89945136 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.81404175 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.64095327 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.62767565 |
| 27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.62584778 |
| 28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.57232238 |
| 29 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.40673704 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35791705 |
| 31 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.35171605 |
| 32 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.27925364 |
| 33 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.25961626 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.22438581 |
| 35 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.21262383 |
| 36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.20096477 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.17435131 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.11551817 |
| 39 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.11492041 |
| 40 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.08229463 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04987268 |
| 42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.99572069 |
| 43 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98058238 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.97109342 |
| 45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.92479569 |
| 46 | Nicotine addiction_Homo sapiens_hsa05033 | 0.89631133 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.86771747 |
| 48 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.81971010 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80220735 |
| 50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.74333273 |
| 51 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.74321193 |
| 52 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.70051203 |
| 53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.68838786 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65564960 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62291491 |
| 56 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.60501401 |
| 57 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.60238487 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60061753 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.58887792 |
| 60 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56696669 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56397633 |
| 62 | Carbon metabolism_Homo sapiens_hsa01200 | 0.55986288 |
| 63 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.53627297 |
| 64 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.50734024 |
| 65 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49175817 |
| 66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.48690424 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.47013926 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.45271426 |
| 69 | Peroxisome_Homo sapiens_hsa04146 | 0.45078479 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41437276 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.41238576 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39807741 |
| 73 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.38563780 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37869936 |
| 75 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.37114814 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35747820 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.35687080 |
| 78 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.35604440 |
| 79 | GABAergic synapse_Homo sapiens_hsa04727 | 0.32571731 |
| 80 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.31909407 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.31890705 |
| 82 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.29903254 |
| 83 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28425869 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26071753 |
| 85 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.25566958 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25128307 |
| 87 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.23153315 |
| 88 | Olfactory transduction_Homo sapiens_hsa04740 | 0.23017285 |
| 89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.18365954 |
| 90 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.14654530 |
| 91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.13182926 |
| 92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.12724773 |
| 93 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.11095554 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.09181270 |
| 95 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.09042655 |
| 96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.08909893 |
| 97 | Morphine addiction_Homo sapiens_hsa05032 | 0.07516262 |
| 98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.07466575 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.07370059 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.04636705 |

