TUBGCP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)7.16507043
2homocysteine metabolic process (GO:0050667)6.09012612
3DNA unwinding involved in DNA replication (GO:0006268)5.53043087
4regulation of plasminogen activation (GO:0010755)4.95015850
5purine nucleotide salvage (GO:0032261)4.75255470
6mitotic chromosome condensation (GO:0007076)4.67103542
7mitotic sister chromatid cohesion (GO:0007064)4.62026418
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.54999157
9protein localization to kinetochore (GO:0034501)4.50025617
10negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.46038962
11nuclear pore complex assembly (GO:0051292)4.21858840
12nuclear pore organization (GO:0006999)4.14442614
13sulfur amino acid catabolic process (GO:0000098)4.14273931
14DNA ligation (GO:0006266)4.12065505
15tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.06868894
16RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.06868894
17negative regulation of RNA splicing (GO:0033119)4.04042675
18DNA strand elongation involved in DNA replication (GO:0006271)4.02057379
19sister chromatid segregation (GO:0000819)4.01097293
20epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)4.00894587
21mitochondrial RNA metabolic process (GO:0000959)3.99353931
22pteridine-containing compound biosynthetic process (GO:0042559)3.96852516
23DNA geometric change (GO:0032392)3.95550523
24DNA duplex unwinding (GO:0032508)3.95432747
25folic acid metabolic process (GO:0046655)3.94941980
26L-serine metabolic process (GO:0006563)3.92098280
27DNA replication initiation (GO:0006270)3.86641376
28DNA strand elongation (GO:0022616)3.86400189
29regulation of histone H3-K9 methylation (GO:0051570)3.85479325
30mitotic nuclear envelope disassembly (GO:0007077)3.83266732
31folic acid-containing compound metabolic process (GO:0006760)3.83042165
32tetrahydrofolate metabolic process (GO:0046653)3.81972652
33translesion synthesis (GO:0019985)3.81107474
34negative regulation of histone methylation (GO:0031061)3.78935942
35telomere maintenance via semi-conservative replication (GO:0032201)3.73034624
36negative regulation of mRNA processing (GO:0050686)3.66597540
37kinetochore organization (GO:0051383)3.63575634
38mitotic sister chromatid segregation (GO:0000070)3.62752098
39IMP biosynthetic process (GO:0006188)3.62606233
40mitotic recombination (GO:0006312)3.62123475
41protein localization to chromosome, centromeric region (GO:0071459)3.60787507
42membrane disassembly (GO:0030397)3.59204707
43nuclear envelope disassembly (GO:0051081)3.59204707
44histone-serine phosphorylation (GO:0035404)3.58910223
45cysteine metabolic process (GO:0006534)3.52109025
46regulation of DNA endoreduplication (GO:0032875)3.51796729
47dosage compensation (GO:0007549)3.51110462
48white fat cell differentiation (GO:0050872)3.49051954
49pore complex assembly (GO:0046931)3.47209874
50telomere maintenance via recombination (GO:0000722)3.45143845
51DNA topological change (GO:0006265)3.41747790
52cellular protein complex localization (GO:0034629)3.40190977
53negative regulation of mRNA metabolic process (GO:1903312)3.39228210
54histone exchange (GO:0043486)3.38837959
55DNA conformation change (GO:0071103)3.37309606
56glucocorticoid receptor signaling pathway (GO:0042921)3.37285558
57adenosine metabolic process (GO:0046085)3.36120707
58histone H4-K12 acetylation (GO:0043983)3.36108080
59mitotic metaphase plate congression (GO:0007080)3.34754157
60regulation of DNA damage checkpoint (GO:2000001)3.33879598
61metaphase plate congression (GO:0051310)3.31912822
62ATP-dependent chromatin remodeling (GO:0043044)3.28927360
63regulation of spindle organization (GO:0090224)3.28722084
64DNA replication checkpoint (GO:0000076)3.27263348
65positive regulation of B cell differentiation (GO:0045579)3.23516312
66regulation of mitotic spindle organization (GO:0060236)3.19133378
67positive regulation of endothelial cell differentiation (GO:0045603)3.16437795
68regulation of vitamin D biosynthetic process (GO:0060556)3.14979427
69protein localization to chromosome (GO:0034502)3.14339528
70COPII vesicle coating (GO:0048208)3.12301476
71chromosome condensation (GO:0030261)3.10249575
72ribosome biogenesis (GO:0042254)3.10170494
73neutrophil activation involved in immune response (GO:0002283)3.10064224
74regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.08932416
75desmosome organization (GO:0002934)3.08756084
76postreplication repair (GO:0006301)3.08368801
77regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.08211729
78negative regulation of DNA biosynthetic process (GO:2000279)3.07641992
79V(D)J recombination (GO:0033151)3.06428805
80serine family amino acid biosynthetic process (GO:0009070)3.06323988
81pre-miRNA processing (GO:0031054)3.04674769
82hepatocyte apoptotic process (GO:0097284)3.04203674
83meiotic chromosome segregation (GO:0045132)3.04150920
84phosphatidylglycerol biosynthetic process (GO:0006655)3.03820746
85regulation of translational fidelity (GO:0006450)3.02230506
86nucleotide salvage (GO:0043173)3.02155787
87alternative mRNA splicing, via spliceosome (GO:0000380)3.01949542
88attachment of spindle microtubules to kinetochore (GO:0008608)3.00185631
89negative regulation of erythrocyte differentiation (GO:0045647)2.99557445
90chromatin assembly or disassembly (GO:0006333)2.98669391
91transcription from mitochondrial promoter (GO:0006390)2.97802772
92histone H4-K8 acetylation (GO:0043982)2.97698117
93histone H4-K5 acetylation (GO:0043981)2.97698117
94negative regulation of necroptotic process (GO:0060546)2.96267950
95nucleotide-excision repair, DNA gap filling (GO:0006297)2.96259486
96positive regulation of chromosome segregation (GO:0051984)2.96223511
97positive regulation of histone H3-K4 methylation (GO:0051571)2.95633497
98DNA packaging (GO:0006323)2.95573166
99nuclear envelope organization (GO:0006998)2.94198288
100mRNA splice site selection (GO:0006376)2.93643917
101cell migration involved in heart development (GO:0060973)2.92373933
102response to vitamin A (GO:0033189)2.92094224
103telomere maintenance via telomere lengthening (GO:0010833)2.92057749
104histone H3-K4 methylation (GO:0051568)2.91140321
105spindle assembly checkpoint (GO:0071173)2.90782076
106protein complex localization (GO:0031503)2.89380025
107DNA replication-independent nucleosome organization (GO:0034724)2.89091216
108DNA replication-independent nucleosome assembly (GO:0006336)2.89091216
109IMP metabolic process (GO:0046040)2.88132755
110establishment of chromosome localization (GO:0051303)2.88008370
1113-UTR-mediated mRNA stabilization (GO:0070935)2.86385686
112positive regulation of gamma-delta T cell activation (GO:0046645)2.83521825
113positive regulation of RNA splicing (GO:0033120)2.83354924
114DNA replication-dependent nucleosome assembly (GO:0006335)2.82923726
115DNA replication-dependent nucleosome organization (GO:0034723)2.82923726
116histone H4-K16 acetylation (GO:0043984)2.82513223
117regulation of chromosome segregation (GO:0051983)2.81991732
118galactose catabolic process (GO:0019388)2.81544366
119mitotic spindle assembly checkpoint (GO:0007094)2.80400514
120regulation of RNA export from nucleus (GO:0046831)2.80134179
121telomere maintenance (GO:0000723)2.79815791
122corticosteroid receptor signaling pathway (GO:0031958)2.79113144
123kinetochore assembly (GO:0051382)2.77905963
124pteridine-containing compound metabolic process (GO:0042558)2.77672992
125negative regulation of chromosome segregation (GO:0051985)2.77437993
126peptidyl-lysine dimethylation (GO:0018027)2.77391891
127histone mRNA catabolic process (GO:0071044)2.77333690
128histone H2A acetylation (GO:0043968)2.76908976
129telomere organization (GO:0032200)2.76783510
130negative regulation of mitotic sister chromatid separation (GO:2000816)2.76722540
131negative regulation of mitotic sister chromatid segregation (GO:0033048)2.76722540
132negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.76722540
133negative regulation of sister chromatid segregation (GO:0033046)2.76722540
134regulation of mitotic metaphase/anaphase transition (GO:0030071)2.76057821
135regulation of sister chromatid cohesion (GO:0007063)2.75722409
136nucleobase biosynthetic process (GO:0046112)2.75027143
137CENP-A containing nucleosome assembly (GO:0034080)2.74484279
138regulation of histone H3-K4 methylation (GO:0051569)2.72341807
139maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.71871327
140chromatin remodeling at centromere (GO:0031055)2.70872864
141positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.68585406
142chromosome segregation (GO:0007059)2.67231388
143protoporphyrinogen IX metabolic process (GO:0046501)2.66847002
144regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.66068025
145protein export from nucleus (GO:0006611)2.65634970
146regulation of superoxide anion generation (GO:0032928)2.65161337
147negative regulation of Ras GTPase activity (GO:0034261)2.65138701
148histone phosphorylation (GO:0016572)2.64978333
149positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.64555895
150positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.64555895
151positive regulation of mitotic sister chromatid separation (GO:1901970)2.64555895
152protoporphyrinogen IX biosynthetic process (GO:0006782)2.64262550
153negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.63775018
154DNA synthesis involved in DNA repair (GO:0000731)2.63106622
155cellular response to heat (GO:0034605)2.62405935
156folic acid transport (GO:0015884)2.57566310
157rRNA methylation (GO:0031167)2.53974061
158polyamine biosynthetic process (GO:0006596)2.53039850

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.66937847
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.16380098
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.15010573
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.88177687
5MYC_22102868_ChIP-Seq_BL_Human3.16422976
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.99238090
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.88040654
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.52900685
9E2F1_21310950_ChIP-Seq_MCF-7_Human2.48960647
10CIITA_25753668_ChIP-Seq_RAJI_Human2.43386635
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.33914202
12AR_21909140_ChIP-Seq_LNCAP_Human2.16203968
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.14495168
14VDR_21846776_ChIP-Seq_THP-1_Human2.13556757
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.08152809
16E2F7_22180533_ChIP-Seq_HELA_Human11.2182485
17ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.95406141
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.92941753
19SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89278177
20GATA1_22025678_ChIP-Seq_K562_Human1.85000964
21YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.83221829
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.82999315
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.78395416
24MYC_19079543_ChIP-ChIP_MESCs_Mouse1.76892539
25MYC_19030024_ChIP-ChIP_MESCs_Mouse1.76287685
26SCL_19346495_ChIP-Seq_HPC-7_Human1.68792333
27XRN2_22483619_ChIP-Seq_HELA_Human1.68095555
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.66703989
29NELFA_20434984_ChIP-Seq_ESCs_Mouse1.66048156
30FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.60308172
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59787518
32TCF7_22412390_ChIP-Seq_EML_Mouse1.56959484
33SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.54263034
34FOXP3_21729870_ChIP-Seq_TREG_Human1.52137213
35HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51685459
36KDM5A_27292631_Chip-Seq_BREAST_Human1.51451200
37SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.49894048
38* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.47101733
39* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.45893821
40MAF_26560356_Chip-Seq_TH1_Human1.41982095
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.41975987
42UTX_26944678_Chip-Seq_JUKART_Human1.40224036
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.39815693
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.39151070
45VDR_23849224_ChIP-Seq_CD4+_Human1.39060581
46MYB_26560356_Chip-Seq_TH1_Human1.36364543
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.36255492
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34411395
49NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33596142
50HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.33436115
51* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.32364976
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32080025
53TP63_19390658_ChIP-ChIP_HaCaT_Human1.31279444
54MAF_26560356_Chip-Seq_TH2_Human1.31241779
55TFEB_21752829_ChIP-Seq_HELA_Human1.30862746
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30392063
57MYB_26560356_Chip-Seq_TH2_Human1.29818101
58ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29438855
59CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.27730844
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25806325
61CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.25619224
62* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25391838
63KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25182000
64KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24352682
65THAP11_20581084_ChIP-Seq_MESCs_Mouse1.22534492
66GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.21784858
67SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.20732068
68TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.18608607
69ETS1_20019798_ChIP-Seq_JURKAT_Human1.18536923
70CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.18518844
71GABP_19822575_ChIP-Seq_HepG2_Human1.17936866
72ELK1_19687146_ChIP-ChIP_HELA_Human1.17199203
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15430404
74IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.15070895
75MYB_21317192_ChIP-Seq_ERMYB_Mouse1.15064775
76JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.15008597
77TTF2_22483619_ChIP-Seq_HELA_Human1.14706703
78VDR_24763502_ChIP-Seq_THP-1_Human1.14661314
79NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.14210737
80DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12111973
81FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.10875236
82* SPI1_23547873_ChIP-Seq_NB4_Human1.10815219
83STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.10463815
84CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.10118363
85RUNX1_22412390_ChIP-Seq_EML_Mouse1.09955587
86MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.09631456
87KDM2B_26808549_Chip-Seq_DND41_Human1.09303081
88ELF1_17652178_ChIP-ChIP_JURKAT_Human1.09280644
89GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08514296
90E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08097678
91IRF8_22096565_ChIP-ChIP_GC-B_Human1.07800880
92CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07319543
93BRD4_27068464_Chip-Seq_AML-cells_Mouse1.06970563
94FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.06943526
95DCP1A_22483619_ChIP-Seq_HELA_Human1.06379927
96PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.06345846
97ZNF263_19887448_ChIP-Seq_K562_Human1.05911155
98* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03234703
99NOTCH1_21737748_ChIP-Seq_TLL_Human1.01802575
100HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01604697
101TBX5_21415370_ChIP-Seq_HL-1_Mouse0.99514725
102KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.99223222
103PKCTHETA_26484144_Chip-Seq_BREAST_Human0.98772589
104MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.98642341
105DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.98496048
106SALL1_21062744_ChIP-ChIP_HESCs_Human0.98052466
107GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97778684
108NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.97118220
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96977036
110* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96193996
111PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96144951
112ELK3_25401928_ChIP-Seq_HUVEC_Human0.95406638
113POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.94593753
114KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94192188
115CREB1_15753290_ChIP-ChIP_HEK293T_Human0.93701502
116RBPJ_22232070_ChIP-Seq_NCS_Mouse0.93507745
117E2F1_18555785_ChIP-Seq_MESCs_Mouse0.91207550
118RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.91142983
119ESR1_15608294_ChIP-ChIP_MCF-7_Human0.90705696
120ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.89896266
121NCOR1_26117541_ChIP-Seq_K562_Human0.89115152
122SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.84174997

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.03343162
2MP0010094_abnormal_chromosome_stability3.89289141
3MP0003111_abnormal_nucleus_morphology3.71246937
4MP0000569_abnormal_digit_pigmentation3.66319035
5MP0003077_abnormal_cell_cycle3.19593205
6MP0002396_abnormal_hematopoietic_system3.17837653
7MP0003693_abnormal_embryo_hatching3.12404147
8MP0004185_abnormal_adipocyte_glucose3.11357118
9MP0004808_abnormal_hematopoietic_stem2.89197904
10MP0003123_paternal_imprinting2.67624531
11MP0005670_abnormal_white_adipose2.59902664
12MP0005360_urolithiasis2.44120869
13MP0006054_spinal_hemorrhage2.37236522
14MP0010307_abnormal_tumor_latency2.34770454
15MP0004957_abnormal_blastocyst_morpholog2.33724203
16MP0008058_abnormal_DNA_repair2.31703185
17MP0010352_gastrointestinal_tract_polyps2.28649270
18MP0009278_abnormal_bone_marrow2.24946086
19MP0005076_abnormal_cell_differentiation2.17917039
20MP0003121_genomic_imprinting2.16540417
21MP0003724_increased_susceptibility_to2.16132435
22MP0002009_preneoplasia2.13282597
23MP0001545_abnormal_hematopoietic_system2.11528642
24MP0005397_hematopoietic_system_phenotyp2.11528642
25MP0001661_extended_life_span2.06820932
26MP0008007_abnormal_cellular_replicative2.02046618
27MP0000350_abnormal_cell_proliferation1.95236600
28MP0008877_abnormal_DNA_methylation1.84385358
29MP0000013_abnormal_adipose_tissue1.82228566
30MP0001730_embryonic_growth_arrest1.78126574
31MP0000490_abnormal_crypts_of1.76294376
32MP0003763_abnormal_thymus_physiology1.74065932
33MP0000703_abnormal_thymus_morphology1.72961528
34MP0002398_abnormal_bone_marrow1.68556142
35MP0002877_abnormal_melanocyte_morpholog1.66509589
36MP0002132_abnormal_respiratory_system1.66325470
37MP0002166_altered_tumor_susceptibility1.45991369
38MP0001697_abnormal_embryo_size1.45743371
39MP0003436_decreased_susceptibility_to1.45380333
40MP0004197_abnormal_fetal_growth/weight/1.42423260
41MP0003122_maternal_imprinting1.41907097
42MP0001851_eye_inflammation1.41591876
43MP0003984_embryonic_growth_retardation1.39278615
44MP0002722_abnormal_immune_system1.38851987
45MP0003786_premature_aging1.38705652
46MP0008932_abnormal_embryonic_tissue1.38208623
47MP0000003_abnormal_adipose_tissue1.38176390
48MP0002088_abnormal_embryonic_growth/wei1.36552537
49MP0001672_abnormal_embryogenesis/_devel1.35995831
50MP0005380_embryogenesis_phenotype1.35995831
51MP0003300_gastrointestinal_ulcer1.33485892
52MP0002080_prenatal_lethality1.33420759
53MP0003787_abnormal_imprinting1.32475149
54MP0000313_abnormal_cell_death1.31440055
55MP0005075_abnormal_melanosome_morpholog1.29596106
56MP0005646_abnormal_pituitary_gland1.28583654
57MP0000689_abnormal_spleen_morphology1.28444289
58MP0002084_abnormal_developmental_patter1.27684837
59MP0002086_abnormal_extraembryonic_tissu1.27072214
60MP0009697_abnormal_copulation1.23990893
61MP0000685_abnormal_immune_system1.23877254
62MP0002006_tumorigenesis1.22927547
63MP0001873_stomach_inflammation1.22186834
64MP0005451_abnormal_body_composition1.19266716
65MP0002085_abnormal_embryonic_tissue1.19103667
66MP0002019_abnormal_tumor_incidence1.18953820
67MP0003943_abnormal_hepatobiliary_system1.18711404
68MP0001800_abnormal_humoral_immune1.18663573
69MP0008995_early_reproductive_senescence1.17972555
70MP0005671_abnormal_response_to1.17266347
71MP0005666_abnormal_adipose_tissue1.13129100
72MP0002429_abnormal_blood_cell1.13099069
73MP0003705_abnormal_hypodermis_morpholog1.12521761
74MP0002419_abnormal_innate_immunity1.11118041
75MP0005000_abnormal_immune_tolerance1.10191817
76MP0000716_abnormal_immune_system1.09721969
77MP0004147_increased_porphyrin_level1.09308114
78MP0000537_abnormal_urethra_morphology1.09279300
79MP0003566_abnormal_cell_adhesion1.07803666
80MP0005174_abnormal_tail_pigmentation1.07242519
81MP0009333_abnormal_splenocyte_physiolog1.07040920
82MP0001293_anophthalmia1.05834135
83MP0010030_abnormal_orbit_morphology1.05398315
84MP0001835_abnormal_antigen_presentation0.99983931
85MP0003221_abnormal_cardiomyocyte_apopto0.99492637
86MP0002420_abnormal_adaptive_immunity0.98752204
87MP0005621_abnormal_cell_physiology0.98688593
88MP0002452_abnormal_antigen_presenting0.97452451
89MP0001819_abnormal_immune_cell0.96907365
90MP0003806_abnormal_nucleotide_metabolis0.96745690
91MP0009703_decreased_birth_body0.96653857
92MP0008260_abnormal_autophagy0.96450994
93MP0005384_cellular_phenotype0.95561130
94MP0000858_altered_metastatic_potential0.94920509
95MP0001915_intracranial_hemorrhage0.94565402
96MP0000733_abnormal_muscle_development0.94523048
97MP0001849_ear_inflammation0.94343453
98MP0005464_abnormal_platelet_physiology0.92770147
99MP0003567_abnormal_fetal_cardiomyocyte0.91016845
100MP0002925_abnormal_cardiovascular_devel0.89788412
101MP0003183_abnormal_peptide_metabolism0.86960612
102MP0003656_abnormal_erythrocyte_physiolo0.85046782
103MP0009672_abnormal_birth_weight0.83393410
104MP0002723_abnormal_immune_serum0.83126285
105MP0009115_abnormal_fat_cell0.82809645
106MP0003890_abnormal_embryonic-extraembry0.81846813
107MP0003045_fibrosis0.81309299
108MP0001764_abnormal_homeostasis0.80168440
109MP0003115_abnormal_respiratory_system0.79849873
110MP0000428_abnormal_craniofacial_morphol0.79045174
111MP0005025_abnormal_response_to0.78343668
112MP0003303_peritoneal_inflammation0.78128211
113MP0002970_abnormal_white_adipose0.77696626
114MP0004130_abnormal_muscle_cell0.77289844
115MP0000747_muscle_weakness0.76002435
116MP0002089_abnormal_postnatal_growth/wei0.75677298
117MP0004233_abnormal_muscle_weight0.75096607
118MP0002210_abnormal_sex_determination0.75025592
119MP0010155_abnormal_intestine_physiology0.74925911
120MP0002095_abnormal_skin_pigmentation0.74611150
121MP0008770_decreased_survivor_rate0.74512138
122MP0004947_skin_inflammation0.73289279
123MP0005375_adipose_tissue_phenotype0.72960284
124MP0001270_distended_abdomen0.72863139
125MP0001145_abnormal_male_reproductive0.72359137
126MP0003091_abnormal_cell_migration0.71094271
127MP0002092_abnormal_eye_morphology0.70180133
128MP0002405_respiratory_system_inflammati0.70107035
129MP0002075_abnormal_coat/hair_pigmentati0.68945923
130MP0008961_abnormal_basal_metabolism0.68912137
131MP0000015_abnormal_ear_pigmentation0.68892929
132MP0000266_abnormal_heart_morphology0.67006916
133MP0005023_abnormal_wound_healing0.66821171
134MP0000371_diluted_coat_color0.64416539
135MP0003935_abnormal_craniofacial_develop0.64298189
136MP0000465_gastrointestinal_hemorrhage0.62969400

Predicted human phenotypes

RankGene SetZ-score
1Spontaneous hematomas (HP:0007420)5.66342716
2Abnormality of pyruvate family amino acid metabolism (HP:0010915)5.39746949
3Abnormality of alanine metabolism (HP:0010916)5.39746949
4Hyperalaninemia (HP:0003348)5.39746949
5Esophageal varix (HP:0002040)4.45541058
6Abnormality of the fingertips (HP:0001211)4.20712948
7Constricted visual fields (HP:0001133)4.11830688
8Birth length less than 3rd percentile (HP:0003561)3.94716408
9Abnormality of the fetal cardiovascular system (HP:0010948)3.92933991
10Abnormal umbilical cord blood vessels (HP:0011403)3.92933991
11Single umbilical artery (HP:0001195)3.92933991
12Fatigue (HP:0012378)3.69207106
13Conjunctival telangiectasia (HP:0000524)3.65883585
14Volvulus (HP:0002580)3.47984649
15Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.46587015
16Short 4th metacarpal (HP:0010044)3.46587015
17White forelock (HP:0002211)3.39307134
18Myocardial infarction (HP:0001658)3.35659204
19Hyperacusis (HP:0010780)3.08394020
20Abnormality of the vasculature of the conjunctiva (HP:0008054)3.07874231
21Increased nuchal translucency (HP:0010880)3.06284113
22Hypopigmentation of the fundus (HP:0007894)3.04440793
23Anorexia (HP:0002039)2.92680287
24Abnormality of homocysteine metabolism (HP:0010919)2.87026232
25Homocystinuria (HP:0002156)2.87026232
26Recurrent abscess formation (HP:0002722)2.86968275
27Patchy hypopigmentation of hair (HP:0011365)2.79812536
28Congenital sensorineural hearing impairment (HP:0008527)2.73466508
29Broad palm (HP:0001169)2.73146124
30Chromsome breakage (HP:0040012)2.70701225
31Prominent nose (HP:0000448)2.68427631
32Abnormality of the umbilical cord (HP:0010881)2.66272810
33Abnormality of chromosome stability (HP:0003220)2.64639394
34IgM deficiency (HP:0002850)2.62284518
35High pitched voice (HP:0001620)2.58706639
36Ependymoma (HP:0002888)2.57875666
37Abnormality of pyrimidine metabolism (HP:0004353)2.53561800
38Arteriovenous malformation (HP:0100026)2.50693778
39Pulmonary embolism (HP:0002204)2.50510049
40Myelodysplasia (HP:0002863)2.49471580
41Bone marrow hypocellularity (HP:0005528)2.43540867
42Long eyelashes (HP:0000527)2.42431907
43Poor speech (HP:0002465)2.41548604
44Thrombophlebitis (HP:0004418)2.41100039
45Recurrent bacterial skin infections (HP:0005406)2.40135555
46Recurrent viral infections (HP:0004429)2.38838280
47Truncal obesity (HP:0001956)2.37570020
48Selective tooth agenesis (HP:0001592)2.37466129
49Thrombocytosis (HP:0001894)2.37355524
50Visceral angiomatosis (HP:0100761)2.37217985
51Duplicated collecting system (HP:0000081)2.36843147
52Granulocytopenia (HP:0001913)2.36271573
53Chromosomal breakage induced by crosslinking agents (HP:0003221)2.36038241
54Ectopic kidney (HP:0000086)2.33946760
55Proximal placement of thumb (HP:0009623)2.33905811
56Trigonocephaly (HP:0000243)2.33064149
57Colon cancer (HP:0003003)2.32910692
58Renovascular hypertension (HP:0100817)2.32767050
59Hemangiomatosis (HP:0007461)2.31938698
60Increased density of long bones (HP:0006392)2.30038208
61Obsessive-compulsive behavior (HP:0000722)2.29173986
62Renal duplication (HP:0000075)2.28451711
63Deviation of the thumb (HP:0009603)2.28412724
64Heterotopia (HP:0002282)2.25711323
65Medulloblastoma (HP:0002885)2.25479170
66Basal cell carcinoma (HP:0002671)2.25234981
67Abnormality of the phalanges of the hallux (HP:0010057)2.23365809
68Cerebral aneurysm (HP:0004944)2.23344574
69Macroorchidism (HP:0000053)2.23026922
70Progressive external ophthalmoplegia (HP:0000590)2.21963824
71Biconcave vertebral bodies (HP:0004586)2.21021947
72Elfin facies (HP:0004428)2.19795430
73Toxemia of pregnancy (HP:0100603)2.18971705
74Heterochromia iridis (HP:0001100)2.18189997
75Long clavicles (HP:0000890)2.17529069
76Cafe-au-lait spot (HP:0000957)2.16912022
77Arterial thrombosis (HP:0004420)2.15215651
78Reduced subcutaneous adipose tissue (HP:0003758)2.15145637
79Abnormality of the carotid arteries (HP:0005344)2.14360891
80Abnormal number of incisors (HP:0011064)2.13174037
81Decreased electroretinogram (ERG) amplitude (HP:0000654)2.13147497
82Aplasia/Hypoplasia of the uvula (HP:0010293)2.11517197
83Hypertensive crisis (HP:0100735)2.10241654
84Abnormality of the 4th metacarpal (HP:0010012)2.09529674
85Gingival bleeding (HP:0000225)2.09510416
86Abnormality of the astrocytes (HP:0100707)2.06083957
87Astrocytoma (HP:0009592)2.06083957
88Abnormality of the renal collecting system (HP:0004742)2.05972522
89Deep philtrum (HP:0002002)2.04255469
90Insomnia (HP:0100785)2.02997048
91Overriding aorta (HP:0002623)2.02491586
92T lymphocytopenia (HP:0005403)2.01583591
93Meckel diverticulum (HP:0002245)2.01370700
94Reticulocytopenia (HP:0001896)2.01289792
95Skin tags (HP:0010609)1.99592195
96Thoracic kyphosis (HP:0002942)1.97670785
97Bowel diverticulosis (HP:0005222)1.97459871
98Disproportionate tall stature (HP:0001519)1.96095317
99Epistaxis (HP:0000421)1.95865808
100Abnormality of the ileum (HP:0001549)1.94369580
101Abnormality of cochlea (HP:0000375)1.94189762
102Metaphyseal cupping (HP:0003021)1.94022402
103Abnormality of the preputium (HP:0100587)1.91839823
104Abnormality of B cell number (HP:0010975)1.91352330
105B lymphocytopenia (HP:0010976)1.91352330
106Duodenal stenosis (HP:0100867)1.91038100
107Small intestinal stenosis (HP:0012848)1.91038100
108Bowel incontinence (HP:0002607)1.90511547
109Abnormality of the thoracic spine (HP:0100711)1.89695607
110Rectal prolapse (HP:0002035)1.89566872
111Complete atrioventricular canal defect (HP:0001674)1.89435318
112Lymphoma (HP:0002665)1.88826885
113Amaurosis fugax (HP:0100576)1.88611957
114Duplication of thumb phalanx (HP:0009942)1.88508508
115Spinal cord lesions (HP:0100561)1.87754402
116Syringomyelia (HP:0003396)1.87754402
117Chronic otitis media (HP:0000389)1.87362325
118Glioma (HP:0009733)1.87322517
119Pointed chin (HP:0000307)1.86138210
120Abnormality of DNA repair (HP:0003254)1.84533403
121Abnormality of the heme biosynthetic pathway (HP:0010472)1.83929871
122Aortic aneurysm (HP:0004942)1.83911023
123Anal stenosis (HP:0002025)1.83509585
124Abnormal large intestine physiology (HP:0012700)1.83109694
125Cutis marmorata (HP:0000965)1.82798749
126Recurrent fungal infections (HP:0002841)1.82091171
127Neoplasm of the oral cavity (HP:0100649)1.81266661
128Petechiae (HP:0000967)1.80953967
129Vertebral arch anomaly (HP:0008438)1.80574299
130Abnormality of T cell number (HP:0011839)1.80084253
131Progressive muscle weakness (HP:0003323)1.79974037
132Absent frontal sinuses (HP:0002688)1.79930836
133Narrow palate (HP:0000189)1.79615331
134Flat acetabular roof (HP:0003180)1.79433849
135Subacute progressive viral hepatitis (HP:0006572)1.79069694
136Premature ovarian failure (HP:0008209)1.78993214
137Agnosia (HP:0010524)1.78444298
138Preauricular skin tag (HP:0000384)1.77316450
139Hypoalphalipoproteinemia (HP:0003233)1.76940618
140Abnormality of serum amino acid levels (HP:0003112)1.76812464
141Malignant gastrointestinal tract tumors (HP:0006749)1.76614458
142Gastrointestinal carcinoma (HP:0002672)1.76614458
143IgA deficiency (HP:0002720)1.75919313
144Acute myeloid leukemia (HP:0004808)1.75513926
145Urticaria (HP:0001025)1.75392302
146Spinal muscular atrophy (HP:0007269)1.74011171
147Colitis (HP:0002583)1.73679885
148Sacral dimple (HP:0000960)1.73671315
149Shallow orbits (HP:0000586)1.73269011
150Enlarged penis (HP:0000040)1.70814658
151Skull defect (HP:0001362)1.70579322
152Conjugated hyperbilirubinemia (HP:0002908)1.70475447
153Cortical visual impairment (HP:0100704)1.69849286
154Carpal bone hypoplasia (HP:0001498)1.69226146
155Polygenic inheritance (HP:0010982)1.68605756
156Ileus (HP:0002595)1.68423672
157Smooth philtrum (HP:0000319)1.67317346
158Cavernous hemangioma (HP:0001048)1.66595744
159Hypergonadotropic hypogonadism (HP:0000815)1.66144981
160Thick eyebrow (HP:0000574)1.65896503
161Bicuspid aortic valve (HP:0001647)1.65373536
162Microcytic anemia (HP:0001935)1.65308976
163Visual hallucinations (HP:0002367)1.64849206
164Elevated alkaline phosphatase (HP:0003155)1.64453511
165Acute lymphatic leukemia (HP:0006721)1.64089704
166Decreased subcutaneous fat (HP:0001002)1.63700267
167Long palpebral fissure (HP:0000637)1.63401858
168Flat cornea (HP:0007720)1.63187636
169Myopathic facies (HP:0002058)1.61797190
170Cone-rod dystrophy (HP:0000548)1.61299944
171Abnormality of cells of the lymphoid lineage (HP:0012140)1.59062386
172Lymphopenia (HP:0001888)1.58145128
173Low anterior hairline (HP:0000294)1.56013782
174Intestinal malrotation (HP:0002566)1.55726760
175Abnormality of the duodenum (HP:0002246)1.55698273
176Poikiloderma (HP:0001029)1.55051351
177Ankle contracture (HP:0006466)1.54422129
178Leukopenia (HP:0001882)1.54198376
179Cutaneous melanoma (HP:0012056)1.54196798

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.97672260
2NEK23.55688711
3MAP3K33.40850376
4CDK123.24097582
5EEF2K3.10525914
6PKN22.77542752
7FGR2.72090149
8PRPF4B2.64775039
9CDK92.51031585
10MAP4K12.30073874
11WEE12.28182115
12SMG11.93670383
13ATR1.93663951
14BRSK21.93245819
15MAP3K101.87444380
16BRD41.80348254
17STK101.77228521
18ICK1.66426731
19CDK41.61782998
20SRPK11.58441915
21NEK11.57266851
22STK31.47790519
23PASK1.46239565
24BUB11.45952708
25CAMK1D1.45830799
26TSSK61.45705750
27SIK21.44634264
28ACVR1B1.40926241
29RIPK41.40305940
30ERN11.39339197
31TRIB31.38026277
32RPS6KA41.36737773
33SGK4941.35922292
34SGK2231.35922292
35SGK21.34791187
36PLK11.32625577
37BRSK11.31277223
38SCYL21.30530490
39TTN1.29932454
40DYRK31.28885016
41IRAK21.27606522
42CCNB11.24898029
43IRAK41.22745624
44MAP3K141.19837136
45STK41.19678365
46PIM11.19304358
47TTK1.19046956
48AURKB1.17549810
49CHEK11.11179399
50JAK31.10501606
51CDK61.09623940
52MARK31.08530780
53KIT1.07051171
54CHEK21.06758731
55TGFBR11.06458950
56EIF2AK11.06265971
57PLK41.05862361
58CLK11.03838210
59LRRK21.03473024
60RPS6KB21.01006311
61PLK31.00835860
62MAP3K81.00591761
63PTK60.97976824
64FGFR10.96818396
65BLK0.95428070
66VRK10.94496429
67ATM0.94215429
68CDK70.93853365
69MTOR0.93782744
70MAPK110.93509737
71FLT30.91950544
72MELK0.91837300
73KSR20.90234238
74ALK0.89623812
75MKNK10.89502284
76CDK20.89460218
77TLK10.86951534
78TYK20.86787765
79YES10.86659714
80CAMK1G0.85842621
81MAP3K130.79232293
82BTK0.78181744
83SIK10.76196148
84NEK60.76050330
85PAK40.75053788
86IRAK30.74594988
87RPS6KA60.73874721
88MAP3K60.73278711
89SIK30.72199599
90CSF1R0.71794191
91MAP2K30.71323586
92CHUK0.69538288
93CDK10.68967927
94TAOK30.68460391
95NTRK20.66400386
96PDGFRA0.65722103
97ZAP700.64520710
98JAK10.63679816
99TXK0.62264840
100RPS6KA50.59584534
101LMTK20.59086776
102FES0.58973556
103TESK20.57450867
104GRK60.57360622
105EIF2AK30.56668692
106RPS6KL10.55636580
107RPS6KC10.55636580
108SYK0.55353582
109TAOK20.54374528
110ZAK0.53690314
111RPS6KA10.52894387
112FGFR30.52862673
113SGK30.51512136
114CAMKK20.51295986
115CDK80.50366017
116AKT20.49896252
117MAP3K110.49734100
118MAP2K10.49567227
119KSR10.48870691
120PRKDC0.48518127
121RAF10.48506107
122UHMK10.45693093
123TBK10.45354030
124ERBB20.44645472
125MAPK140.44212788
126STK240.44016931
127DAPK10.43251378
128MAP3K10.41442240
129RPS6KB10.40989658
130RPS6KA20.40360741
131MATK0.40020533
132JAK20.39757093
133HCK0.39109957
134AURKA0.38299166
135NEK90.38148229
136CSK0.37959796
137MAPKAPK20.31338599
138DYRK1B0.31337579
139IRAK10.30485293
140EGFR0.30260688
141AKT10.30075755
142BRAF0.29141945
143LCK0.28931475
144CDK30.28333929

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.97753295
2Mismatch repair_Homo sapiens_hsa034303.09873784
3Cell cycle_Homo sapiens_hsa041102.71378276
4Base excision repair_Homo sapiens_hsa034102.40630632
5Spliceosome_Homo sapiens_hsa030402.24784075
6Homologous recombination_Homo sapiens_hsa034402.23845127
7RNA transport_Homo sapiens_hsa030132.08572122
82-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.00275832
9One carbon pool by folate_Homo sapiens_hsa006701.91603167
10mRNA surveillance pathway_Homo sapiens_hsa030151.91065952
11Arginine biosynthesis_Homo sapiens_hsa002201.86185787
12Nucleotide excision repair_Homo sapiens_hsa034201.86112449
13Biosynthesis of amino acids_Homo sapiens_hsa012301.79047497
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.77466311
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76538396
16Fanconi anemia pathway_Homo sapiens_hsa034601.76249145
17Non-homologous end-joining_Homo sapiens_hsa034501.69532571
18Chronic myeloid leukemia_Homo sapiens_hsa052201.52839047
19Sulfur relay system_Homo sapiens_hsa041221.49434719
20Herpes simplex infection_Homo sapiens_hsa051681.46777680
21Primary immunodeficiency_Homo sapiens_hsa053401.46762841
22Systemic lupus erythematosus_Homo sapiens_hsa053221.44434861
23Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.42353386
24Viral carcinogenesis_Homo sapiens_hsa052031.40528485
25Other glycan degradation_Homo sapiens_hsa005111.38259759
26p53 signaling pathway_Homo sapiens_hsa041151.35743718
27Small cell lung cancer_Homo sapiens_hsa052221.30385785
28Antigen processing and presentation_Homo sapiens_hsa046121.29101283
29Galactose metabolism_Homo sapiens_hsa000521.27212436
30HTLV-I infection_Homo sapiens_hsa051661.22067137
31Colorectal cancer_Homo sapiens_hsa052101.21782401
32MicroRNAs in cancer_Homo sapiens_hsa052061.18709594
33Non-small cell lung cancer_Homo sapiens_hsa052231.16352175
34B cell receptor signaling pathway_Homo sapiens_hsa046621.16074433
35Oocyte meiosis_Homo sapiens_hsa041141.15649930
36Hepatitis B_Homo sapiens_hsa051611.14319744
37RNA degradation_Homo sapiens_hsa030181.12912042
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.11454661
39Epstein-Barr virus infection_Homo sapiens_hsa051691.10244325
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.08963018
41Measles_Homo sapiens_hsa051621.06459076
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05483440
43Pancreatic cancer_Homo sapiens_hsa052121.02564853
44Neurotrophin signaling pathway_Homo sapiens_hsa047221.01855466
45Acute myeloid leukemia_Homo sapiens_hsa052210.98617393
46Endometrial cancer_Homo sapiens_hsa052130.98594342
47Lysine degradation_Homo sapiens_hsa003100.95791894
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92737628
49Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.92046407
50Alcoholism_Homo sapiens_hsa050340.91868476
51Pentose phosphate pathway_Homo sapiens_hsa000300.90351183
52NF-kappa B signaling pathway_Homo sapiens_hsa040640.90346826
53mTOR signaling pathway_Homo sapiens_hsa041500.89641022
54Apoptosis_Homo sapiens_hsa042100.89237566
55Leishmaniasis_Homo sapiens_hsa051400.85878008
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.84364513
57Influenza A_Homo sapiens_hsa051640.82854812
58Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.82676921
59Bladder cancer_Homo sapiens_hsa052190.81356968
60T cell receptor signaling pathway_Homo sapiens_hsa046600.80820330
61Pyrimidine metabolism_Homo sapiens_hsa002400.80525816
62NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79247092
63Notch signaling pathway_Homo sapiens_hsa043300.79083754
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77753406
65Thyroid cancer_Homo sapiens_hsa052160.77290434
66Osteoclast differentiation_Homo sapiens_hsa043800.76556575
67Legionellosis_Homo sapiens_hsa051340.76043417
68Toxoplasmosis_Homo sapiens_hsa051450.75746926
69Prostate cancer_Homo sapiens_hsa052150.75625592
70Hematopoietic cell lineage_Homo sapiens_hsa046400.75434348
71N-Glycan biosynthesis_Homo sapiens_hsa005100.74628870
72Platelet activation_Homo sapiens_hsa046110.74166197
73Glioma_Homo sapiens_hsa052140.72890744
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72424646
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.71984092
76Vibrio cholerae infection_Homo sapiens_hsa051100.71461933
77Viral myocarditis_Homo sapiens_hsa054160.71452904
78Renal cell carcinoma_Homo sapiens_hsa052110.71051747
79Proteoglycans in cancer_Homo sapiens_hsa052050.70781364
80Central carbon metabolism in cancer_Homo sapiens_hsa052300.70209873
81TNF signaling pathway_Homo sapiens_hsa046680.69027943
82Collecting duct acid secretion_Homo sapiens_hsa049660.68634575
83FoxO signaling pathway_Homo sapiens_hsa040680.66953606
84Shigellosis_Homo sapiens_hsa051310.66597524
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.65513722
86Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65480113
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.63859714
88RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.63602901
89Selenocompound metabolism_Homo sapiens_hsa004500.62464269
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.61733654
91Pathways in cancer_Homo sapiens_hsa052000.60274227
92Carbon metabolism_Homo sapiens_hsa012000.60237453
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.57899052
94Adherens junction_Homo sapiens_hsa045200.57360320
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.57090957
96HIF-1 signaling pathway_Homo sapiens_hsa040660.55803414
97Chemokine signaling pathway_Homo sapiens_hsa040620.54632541
98Focal adhesion_Homo sapiens_hsa045100.53404873
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.51925087
100AMPK signaling pathway_Homo sapiens_hsa041520.51240689
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51205903
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50979379
103Toll-like receptor signaling pathway_Homo sapiens_hsa046200.50795104
104RNA polymerase_Homo sapiens_hsa030200.49917687
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.48597466
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48083300
107ErbB signaling pathway_Homo sapiens_hsa040120.47865024
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46859437
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.46077346
110Prolactin signaling pathway_Homo sapiens_hsa049170.45625020
111GnRH signaling pathway_Homo sapiens_hsa049120.45267466
112Tuberculosis_Homo sapiens_hsa051520.44550998
113Hippo signaling pathway_Homo sapiens_hsa043900.43868321
114Choline metabolism in cancer_Homo sapiens_hsa052310.43811083
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43408037
116Basal transcription factors_Homo sapiens_hsa030220.43400967
117Inositol phosphate metabolism_Homo sapiens_hsa005620.42829444
118VEGF signaling pathway_Homo sapiens_hsa043700.41794593
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41575746
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41209209
121Hepatitis C_Homo sapiens_hsa051600.40068000
122Type II diabetes mellitus_Homo sapiens_hsa049300.39896370
123Insulin resistance_Homo sapiens_hsa049310.39711809
124Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.39625085
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.39345629

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