TUBGCP5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1replication fork processing (GO:0031297)3.92495334
2histone H3-K4 trimethylation (GO:0080182)3.83981224
3response to pheromone (GO:0019236)3.72303529
4regulation of DNA endoreduplication (GO:0032875)3.65154404
5RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.54362836
6somatic diversification of immune receptors via somatic mutation (GO:0002566)3.51121285
7somatic hypermutation of immunoglobulin genes (GO:0016446)3.51121285
8synapsis (GO:0007129)3.48161301
9regulation of mitotic spindle checkpoint (GO:1903504)3.43565884
10regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.43565884
11resolution of meiotic recombination intermediates (GO:0000712)3.41277061
12recombinational repair (GO:0000725)3.39727174
13double-strand break repair via homologous recombination (GO:0000724)3.36066384
14mitochondrial RNA metabolic process (GO:0000959)3.28679078
15microglial cell activation (GO:0001774)3.24071067
16L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.14799436
17respiratory chain complex IV assembly (GO:0008535)3.14401550
18DNA replication-dependent nucleosome assembly (GO:0006335)3.03185738
19DNA replication-dependent nucleosome organization (GO:0034723)3.03185738
20cellular ketone body metabolic process (GO:0046950)3.01619442
21protein K11-linked deubiquitination (GO:0035871)3.01452182
22maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.00113835
23regulation of centriole replication (GO:0046599)2.98333510
24maturation of 5.8S rRNA (GO:0000460)2.95457068
25behavioral response to nicotine (GO:0035095)2.89804227
26peptidyl-lysine trimethylation (GO:0018023)2.86000350
27detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.85498753
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.83867146
29regulation of nuclear cell cycle DNA replication (GO:0033262)2.81998744
30ketone body metabolic process (GO:1902224)2.80215783
31preassembly of GPI anchor in ER membrane (GO:0016254)2.74492401
32positive regulation of histone H3-K4 methylation (GO:0051571)2.72841933
33nuclear pore organization (GO:0006999)2.72635927
34regulation of cilium movement (GO:0003352)2.69602773
35DNA ligation (GO:0006266)2.69429905
36ubiquinone biosynthetic process (GO:0006744)2.68463472
37protein K6-linked ubiquitination (GO:0085020)2.67642322
38protein polyglutamylation (GO:0018095)2.66652847
39peptidyl-histidine modification (GO:0018202)2.65714702
40negative regulation of DNA-dependent DNA replication (GO:2000104)2.65646020
41postreplication repair (GO:0006301)2.65398101
42L-fucose catabolic process (GO:0042355)2.65394474
43fucose catabolic process (GO:0019317)2.65394474
44L-fucose metabolic process (GO:0042354)2.65394474
45amino acid salvage (GO:0043102)2.65061007
46L-methionine salvage (GO:0071267)2.65061007
47L-methionine biosynthetic process (GO:0071265)2.65061007
48somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.63749784
49isotype switching (GO:0045190)2.63749784
50somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.63749784
51protein prenylation (GO:0018342)2.63718926
52prenylation (GO:0097354)2.63718926
53somatic diversification of immunoglobulins (GO:0016445)2.63139410
54cytochrome complex assembly (GO:0017004)2.62840208
55nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.61987391
56non-recombinational repair (GO:0000726)2.60939954
57double-strand break repair via nonhomologous end joining (GO:0006303)2.60939954
58mRNA splice site selection (GO:0006376)2.60630025
59branched-chain amino acid catabolic process (GO:0009083)2.60155462
60dopamine transport (GO:0015872)2.59419423
61nuclear pore complex assembly (GO:0051292)2.59034868
62double-strand break repair (GO:0006302)2.58921094
63histone H2A acetylation (GO:0043968)2.58580514
64mitochondrial respiratory chain complex assembly (GO:0033108)2.56676099
65methionine biosynthetic process (GO:0009086)2.55146628
66microtubule anchoring (GO:0034453)2.54856168
67DNA catabolic process, exonucleolytic (GO:0000738)2.54152307
68mannosylation (GO:0097502)2.54066508
69protein complex biogenesis (GO:0070271)2.53869649
70regulation of meiosis I (GO:0060631)2.53260669
71tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.52747607
72RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.52747607
73attachment of spindle microtubules to kinetochore (GO:0008608)2.51972460
74mitotic sister chromatid cohesion (GO:0007064)2.51545324
75histone exchange (GO:0043486)2.50698911
76water-soluble vitamin biosynthetic process (GO:0042364)2.50062949
77nonmotile primary cilium assembly (GO:0035058)2.50054061
78ubiquinone metabolic process (GO:0006743)2.46485671
79DNA methylation involved in gamete generation (GO:0043046)2.46054072
80monocyte differentiation (GO:0030224)2.45811971
81pseudouridine synthesis (GO:0001522)2.44542351
82regulation of centrosome cycle (GO:0046605)2.44273222
83cilium morphogenesis (GO:0060271)2.44096893
84rRNA modification (GO:0000154)2.43425905
85DNA recombination (GO:0006310)2.43229889
86rRNA methylation (GO:0031167)2.42447540
87C4-dicarboxylate transport (GO:0015740)2.42055440
88intra-S DNA damage checkpoint (GO:0031573)2.42022922
89protein deneddylation (GO:0000338)2.41398186
90DNA-dependent DNA replication (GO:0006261)2.41359075
91mitochondrial respiratory chain complex I assembly (GO:0032981)2.41298644
92NADH dehydrogenase complex assembly (GO:0010257)2.41298644
93mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.41298644
94cullin deneddylation (GO:0010388)2.40972510
95translesion synthesis (GO:0019985)2.40536457
96pyrimidine dimer repair (GO:0006290)2.40124468
97regulation of centrosome duplication (GO:0010824)2.39783551
98signal peptide processing (GO:0006465)2.39714523
99DNA topological change (GO:0006265)2.36711525
100pore complex assembly (GO:0046931)2.36392466
101kinetochore organization (GO:0051383)2.35463851
102negative regulation of translation, ncRNA-mediated (GO:0040033)2.35408525
103regulation of translation, ncRNA-mediated (GO:0045974)2.35408525
104negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.35408525
105positive regulation of cardiac muscle cell differentiation (GO:2000727)2.34691914
106viral mRNA export from host cell nucleus (GO:0046784)2.30622478
107centriole replication (GO:0007099)2.29519339
108positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.29251827
109G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.27978142
110chromatin remodeling at centromere (GO:0031055)2.24352959
111histone H3-K4 methylation (GO:0051568)2.20508767
112CENP-A containing nucleosome assembly (GO:0034080)2.19831657
113reciprocal meiotic recombination (GO:0007131)2.19741818
114reciprocal DNA recombination (GO:0035825)2.19741818
115membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.18691562
116positive regulation of meiosis (GO:0045836)2.18569013
117regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.18018689
118DNA unwinding involved in DNA replication (GO:0006268)2.17643339
119DNA replication initiation (GO:0006270)2.16858209
120DNA replication checkpoint (GO:0000076)2.16142798
121rRNA catabolic process (GO:0016075)2.13747224
122microtubule depolymerization (GO:0007019)2.13598907
123mast cell activation involved in immune response (GO:0002279)2.13512617
124mast cell degranulation (GO:0043303)2.13512617
125kinetochore assembly (GO:0051382)2.13510325
126regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.13403614
127monoubiquitinated protein deubiquitination (GO:0035520)2.12733928
128positive regulation of histone methylation (GO:0031062)2.11225524
129sister chromatid cohesion (GO:0007062)2.10497081
130DNA damage response, detection of DNA damage (GO:0042769)2.09848039
131regulation of helicase activity (GO:0051095)2.08920656
132histone H3-K36 demethylation (GO:0070544)2.07921665
133negative regulation of neurotransmitter secretion (GO:0046929)2.06752092
134regulation of mRNA splicing, via spliceosome (GO:0048024)2.05765293
135transcription elongation from RNA polymerase I promoter (GO:0006362)2.04864325
136positive regulation of chemokine secretion (GO:0090197)2.04767751
137negative regulation of mast cell activation (GO:0033004)2.04022638
138neurotransmitter uptake (GO:0001504)2.03739148
139regulation of histone H3-K27 methylation (GO:0061085)2.03640091
140gamma-aminobutyric acid signaling pathway (GO:0007214)2.03295945
141positive regulation of granulocyte differentiation (GO:0030854)2.03230822
142Golgi to endosome transport (GO:0006895)2.02869027
143negative regulation of neurotransmitter transport (GO:0051589)2.02592482
144mitotic chromosome condensation (GO:0007076)2.02466754
145presynaptic membrane assembly (GO:0097105)2.02181172
146regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.01914585
147negative regulation of synaptic transmission, GABAergic (GO:0032229)2.01060350
148DNA replication-independent nucleosome organization (GO:0034724)1.99679038
149DNA replication-independent nucleosome assembly (GO:0006336)1.99679038
150negative regulation of DNA recombination (GO:0045910)1.99628344
151mitotic recombination (GO:0006312)1.99210608
152positive regulation of meiotic cell cycle (GO:0051446)1.99029136
153phagocytosis, engulfment (GO:0006911)1.98590507
154oogenesis (GO:0048477)1.98533334
155regulation of synapse maturation (GO:0090128)1.98297130
156piRNA metabolic process (GO:0034587)1.96832352
157meiotic chromosome segregation (GO:0045132)1.96514900
158mesenchymal cell differentiation involved in renal system development (GO:2001012)1.96381952
159mesenchymal cell differentiation involved in kidney development (GO:0072161)1.96381952
160V(D)J recombination (GO:0033151)1.95947378
161termination of RNA polymerase I transcription (GO:0006363)1.95740634
162G-protein coupled glutamate receptor signaling pathway (GO:0007216)1.94856947
163DNA double-strand break processing (GO:0000729)1.94579273
164transcription from RNA polymerase III promoter (GO:0006383)1.94567024
165histone H3-K9 methylation (GO:0051567)1.94562244
166regulation of spindle checkpoint (GO:0090231)1.93846694
167response to X-ray (GO:0010165)1.92311386
168ncRNA catabolic process (GO:0034661)1.91662346
169snRNA transcription (GO:0009301)1.91515041
170developmental pigmentation (GO:0048066)1.91052687
171mesenchymal cell differentiation (GO:0048762)1.90950041
172alternative mRNA splicing, via spliceosome (GO:0000380)1.90763998
173centrosome duplication (GO:0051298)1.90514884
174peptidyl-threonine dephosphorylation (GO:0035970)1.90384003
175neuron cell-cell adhesion (GO:0007158)1.89022743
176regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)1.88758582
177dentate gyrus development (GO:0021542)1.88162265
178somatic recombination of immunoglobulin gene segments (GO:0016447)1.87181546
179interleukin-6-mediated signaling pathway (GO:0070102)1.86317717
180exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 1.86072229

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.31138422
2* ZNF274_21170338_ChIP-Seq_K562_Hela3.34772809
3GBX2_23144817_ChIP-Seq_PC3_Human3.01748165
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.88518835
5E2F4_17652178_ChIP-ChIP_JURKAT_Human2.55294564
6FUS_26573619_Chip-Seq_HEK293_Human2.50313278
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.42322401
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.39276881
9TAF15_26573619_Chip-Seq_HEK293_Human2.38398790
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.36892852
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.36264587
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.31267061
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.22600669
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.16083016
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12134827
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.11545926
17EWS_26573619_Chip-Seq_HEK293_Human2.02620352
18IGF1R_20145208_ChIP-Seq_DFB_Human1.90571751
19RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89767890
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.89083654
21POU5F1_16153702_ChIP-ChIP_HESCs_Human1.83001599
22SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.82625175
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.80485478
24FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.79323132
25VDR_22108803_ChIP-Seq_LS180_Human1.78585686
26IRF1_19129219_ChIP-ChIP_H3396_Human1.76976981
27VDR_23849224_ChIP-Seq_CD4+_Human1.74122350
28P300_19829295_ChIP-Seq_ESCs_Human1.73238181
29HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.70825700
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.66166724
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65723070
32FOXM1_23109430_ChIP-Seq_U2OS_Human1.64845462
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.62991473
34IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.60848533
35CBP_20019798_ChIP-Seq_JUKART_Human1.60848533
36ETS1_20019798_ChIP-Seq_JURKAT_Human1.58549072
37BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.57453731
38* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.56374784
39NANOG_18555785_Chip-Seq_ESCs_Mouse1.52374940
40YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51619341
41TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.51142206
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49219453
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48198184
44MYC_18940864_ChIP-ChIP_HL60_Human1.45019944
45KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.44886354
46* SRF_21415370_ChIP-Seq_HL-1_Mouse1.44256187
47RNF2_27304074_Chip-Seq_NSC_Mouse1.42929067
48* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42843298
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.42636006
50E2F1_18555785_Chip-Seq_ESCs_Mouse1.41385967
51CREB1_15753290_ChIP-ChIP_HEK293T_Human1.40790372
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40708124
53CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39678445
54SMAD4_21799915_ChIP-Seq_A2780_Human1.39420358
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38657749
56SMAD3_21741376_ChIP-Seq_EPCs_Human1.38088428
57NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.36467701
58EZH2_22144423_ChIP-Seq_EOC_Human1.35527442
59FOXP3_21729870_ChIP-Seq_TREG_Human1.35153601
60SUZ12_27294783_Chip-Seq_NPCs_Mouse1.34229637
61EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33610101
62PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32602808
63SUZ12_18555785_Chip-Seq_ESCs_Mouse1.29856933
64BCAT_22108803_ChIP-Seq_LS180_Human1.29178010
65EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.28042709
66NFE2_27457419_Chip-Seq_LIVER_Mouse1.27659795
67HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.26964694
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26640585
69ER_23166858_ChIP-Seq_MCF-7_Human1.25573940
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.23353363
71ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.23052994
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22864006
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.22357699
74SOX9_26525672_Chip-Seq_HEART_Mouse1.22130733
75CBX2_27304074_Chip-Seq_ESCs_Mouse1.21008966
76STAT3_18555785_Chip-Seq_ESCs_Mouse1.20415539
77ELK1_19687146_ChIP-ChIP_HELA_Human1.20071581
78P53_22387025_ChIP-Seq_ESCs_Mouse1.18648903
79* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18608927
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18105483
81* STAT3_23295773_ChIP-Seq_U87_Human1.17596805
82TP53_22573176_ChIP-Seq_HFKS_Human1.16883170
83GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16640948
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14619720
85TCF4_22108803_ChIP-Seq_LS180_Human1.14518909
86NMYC_18555785_Chip-Seq_ESCs_Mouse1.13545479
87AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13482285
88RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.12906897
89AR_21572438_ChIP-Seq_LNCaP_Human1.12373418
90NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12291764
91P300_18555785_Chip-Seq_ESCs_Mouse1.12146888
92TCF4_23295773_ChIP-Seq_U87_Human1.11230240
93KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10555502
94E2F1_21310950_ChIP-Seq_MCF-7_Human1.09668114
95RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08828911
96TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08776193
97CRX_20693478_ChIP-Seq_RETINA_Mouse1.07963557
98FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07778425
99NANOG_19829295_ChIP-Seq_ESCs_Human1.07472815
100SOX2_19829295_ChIP-Seq_ESCs_Human1.07472815
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06869440
102WT1_19549856_ChIP-ChIP_CCG9911_Human1.06770266
103CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06658815
104* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04285165
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04235849
106SOX2_18555785_Chip-Seq_ESCs_Mouse1.04187056
107OCT4_18555785_Chip-Seq_ESCs_Mouse1.04076773
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01922306
109POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01922306
110SOX2_16153702_ChIP-ChIP_HESCs_Human1.01200695
111PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00957870
112* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00814128
113RUNX2_22187159_ChIP-Seq_PCA_Human1.00663596
114BP1_19119308_ChIP-ChIP_Hs578T_Human0.99190181
115SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98683053
116AR_25329375_ChIP-Seq_VCAP_Human0.98653192
117NOTCH1_21737748_ChIP-Seq_TLL_Human0.98179613
118CIITA_25753668_ChIP-Seq_RAJI_Human0.97905841
119EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97691287
120GABP_19822575_ChIP-Seq_HepG2_Human0.97185377
121* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97123228
122PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97119090
123JARID2_20064375_ChIP-Seq_MESCs_Mouse0.97086763
124FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.95155607
125FOXA1_21572438_ChIP-Seq_LNCaP_Human0.95148794
126RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94932896
127CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.94661930
128FLI1_21867929_ChIP-Seq_TH2_Mouse0.94144372
129RUNX1_27457419_Chip-Seq_LIVER_Mouse0.92919210
130IKZF1_21737484_ChIP-ChIP_HCT116_Human0.92560717
131TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91327317
132EZH2_27294783_Chip-Seq_NPCs_Mouse0.90836854
133KLF4_18555785_Chip-Seq_ESCs_Mouse0.90131969
134FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.89319556
135SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.89298580
136TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88376039
137MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.87952350
138SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87632032

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.53210713
2MP0008057_abnormal_DNA_replication3.17261495
3MP0003787_abnormal_imprinting2.83058024
4MP0001188_hyperpigmentation2.47431320
5MP0010094_abnormal_chromosome_stability2.41610769
6MP0003880_abnormal_central_pattern2.41134531
7MP0000569_abnormal_digit_pigmentation2.33027885
8MP0004147_increased_porphyrin_level2.31290424
9MP0003121_genomic_imprinting2.17408594
10MP0008058_abnormal_DNA_repair2.16592235
11MP0006292_abnormal_olfactory_placode2.10734789
12MP0005409_darkened_coat_color2.08438038
13MP0003890_abnormal_embryonic-extraembry2.04586144
14MP0001986_abnormal_taste_sensitivity1.87308165
15MP0003122_maternal_imprinting1.86980190
16MP0003693_abnormal_embryo_hatching1.85272701
17MP0005171_absent_coat_pigmentation1.84739330
18MP0003646_muscle_fatigue1.83374192
19MP0009046_muscle_twitch1.71333001
20MP0008007_abnormal_cellular_replicative1.69257192
21MP0002837_dystrophic_cardiac_calcinosis1.64769122
22MP0003718_maternal_effect1.63063409
23MP0009697_abnormal_copulation1.62415118
24MP0001968_abnormal_touch/_nociception1.58800096
25MP0003195_calcinosis1.58369931
26MP0000015_abnormal_ear_pigmentation1.56551886
27MP0009745_abnormal_behavioral_response1.55768636
28MP0001486_abnormal_startle_reflex1.48912798
29MP0000383_abnormal_hair_follicle1.47207542
30MP0004215_abnormal_myocardial_fiber1.43532505
31MP0003077_abnormal_cell_cycle1.42302532
32MP0003635_abnormal_synaptic_transmissio1.41196589
33MP0002736_abnormal_nociception_after1.41076735
34MP0000566_synostosis1.40606232
35MP0003136_yellow_coat_color1.37867774
36MP0002064_seizures1.35441603
37MP0001905_abnormal_dopamine_level1.35364443
38MP0004808_abnormal_hematopoietic_stem1.33751222
39MP0003111_abnormal_nucleus_morphology1.31627524
40MP0002572_abnormal_emotion/affect_behav1.30790071
41MP0003123_paternal_imprinting1.28735144
42MP0002557_abnormal_social/conspecific_i1.28238272
43MP0008789_abnormal_olfactory_epithelium1.27783663
44MP0002095_abnormal_skin_pigmentation1.26278062
45MP0002009_preneoplasia1.25932925
46MP0002734_abnormal_mechanical_nocicepti1.25340201
47MP0005671_abnormal_response_to1.24541026
48MP0001529_abnormal_vocalization1.21905008
49MP0002272_abnormal_nervous_system1.18091011
50MP0008872_abnormal_physiological_respon1.18027746
51MP0002063_abnormal_learning/memory/cond1.17360697
52MP0002638_abnormal_pupillary_reflex1.11499490
53MP0004270_analgesia1.10968720
54MP0004043_abnormal_pH_regulation1.09929567
55MP0002067_abnormal_sensory_capabilities1.09695394
56MP0005646_abnormal_pituitary_gland1.08871872
57MP0005389_reproductive_system_phenotype1.08134084
58MP0003943_abnormal_hepatobiliary_system1.07980567
59MP0004859_abnormal_synaptic_plasticity1.06177098
60MP0002876_abnormal_thyroid_physiology1.06173615
61MP0006082_CNS_inflammation1.05981370
62MP0001501_abnormal_sleep_pattern1.05337399
63MP0008875_abnormal_xenobiotic_pharmacok1.03887634
64MP0001346_abnormal_lacrimal_gland1.03599944
65MP0002254_reproductive_system_inflammat1.02887982
66MP0006072_abnormal_retinal_apoptosis1.02308854
67MP0000631_abnormal_neuroendocrine_gland1.01603872
68MP0005645_abnormal_hypothalamus_physiol1.00805680
69MP0005551_abnormal_eye_electrophysiolog1.00093483
70MP0006035_abnormal_mitochondrial_morpho0.99996343
71MP0004133_heterotaxia0.99114943
72MP0008569_lethality_at_weaning0.99101226
73MP0001485_abnormal_pinna_reflex0.97187707
74MP0005174_abnormal_tail_pigmentation0.96377619
75MP0005408_hypopigmentation0.95371642
76MP0001764_abnormal_homeostasis0.93161429
77MP0002396_abnormal_hematopoietic_system0.93158395
78MP0003011_delayed_dark_adaptation0.92479910
79MP0005391_vision/eye_phenotype0.91027198
80MP0002751_abnormal_autonomic_nervous0.90307844
81MP0003252_abnormal_bile_duct0.90165063
82MP0001293_anophthalmia0.89890364
83MP0005423_abnormal_somatic_nervous0.89388853
84MP0002234_abnormal_pharynx_morphology0.89011976
85MP0000778_abnormal_nervous_system0.88721565
86MP0002102_abnormal_ear_morphology0.88636533
87MP0002210_abnormal_sex_determination0.88540426
88MP0002277_abnormal_respiratory_mucosa0.87681258
89MP0000681_abnormal_thyroid_gland0.87679984
90MP0002928_abnormal_bile_duct0.87306583
91MP0003950_abnormal_plasma_membrane0.86425675
92MP0004142_abnormal_muscle_tone0.86405331
93MP0001963_abnormal_hearing_physiology0.86399357
94MP0005195_abnormal_posterior_eye0.86174766
95MP0002163_abnormal_gland_morphology0.84878537
96MP0005266_abnormal_metabolism0.83665167
97MP0006036_abnormal_mitochondrial_physio0.83593326
98MP0004957_abnormal_blastocyst_morpholog0.82838403
99MP0010678_abnormal_skin_adnexa0.82608405
100MP0002184_abnormal_innervation0.82351572
101MP0004924_abnormal_behavior0.82137282
102MP0005386_behavior/neurological_phenoty0.82137282
103MP0003937_abnormal_limbs/digits/tail_de0.81974198
104MP0005187_abnormal_penis_morphology0.81662033
105MP0000358_abnormal_cell_content/0.81661145
106MP0001177_atelectasis0.81320349
107MP0001324_abnormal_eye_pigmentation0.80831483
108MP0001984_abnormal_olfaction0.80375369
109MP0003786_premature_aging0.80167111
110MP0002090_abnormal_vision0.79378026
111MP0000647_abnormal_sebaceous_gland0.79124272
112MP0002160_abnormal_reproductive_system0.78261768
113MP0000049_abnormal_middle_ear0.77441839
114MP0002177_abnormal_outer_ear0.77153253
115MP0003567_abnormal_fetal_cardiomyocyte0.76037496
116MP0001502_abnormal_circadian_rhythm0.75575205
117MP0005379_endocrine/exocrine_gland_phen0.75008051
118MP0008932_abnormal_embryonic_tissue0.74786090
119MP0002735_abnormal_chemical_nociception0.74759125
120MP0005253_abnormal_eye_physiology0.74453398
121MP0004145_abnormal_muscle_electrophysio0.73943166
122MP0005084_abnormal_gallbladder_morpholo0.73708408
123MP0001145_abnormal_male_reproductive0.73093381
124MP0000653_abnormal_sex_gland0.72288250
125MP0000703_abnormal_thymus_morphology0.72188137
126MP0008260_abnormal_autophagy0.71748528
127MP0002398_abnormal_bone_marrow0.71073776
128MP0000427_abnormal_hair_cycle0.68342033
129MP0001879_abnormal_lymphatic_vessel0.67864032
130MP0001929_abnormal_gametogenesis0.67514665
131MP0000372_irregular_coat_pigmentation0.67067349
132MP0002882_abnormal_neuron_morphology0.65577768
133MP0003698_abnormal_male_reproductive0.64836888
134MP0005075_abnormal_melanosome_morpholog0.64277213
135MP0002938_white_spotting0.63679983
136MP0003879_abnormal_hair_cell0.62754050
137MP0006276_abnormal_autonomic_nervous0.61654031
138MP0004134_abnormal_chest_morphology0.60404226
139MP0005499_abnormal_olfactory_system0.60352748
140MP0005394_taste/olfaction_phenotype0.60352748
141MP0003690_abnormal_glial_cell0.60249651

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.71700085
2True hermaphroditism (HP:0010459)3.07840613
3Volvulus (HP:0002580)3.04546554
4Focal motor seizures (HP:0011153)2.97405498
5Chromsome breakage (HP:0040012)2.86926807
6Epileptic encephalopathy (HP:0200134)2.86366540
7Colon cancer (HP:0003003)2.82204133
8Febrile seizures (HP:0002373)2.73728611
9Urethral obstruction (HP:0000796)2.72565110
10Chromosomal breakage induced by crosslinking agents (HP:0003221)2.69401540
11Congenital primary aphakia (HP:0007707)2.66588543
12Gait imbalance (HP:0002141)2.62746072
13Nephronophthisis (HP:0000090)2.59875338
14Protruding tongue (HP:0010808)2.50433522
15Congenital stationary night blindness (HP:0007642)2.48661569
16Birth length less than 3rd percentile (HP:0003561)2.46955128
17Stomach cancer (HP:0012126)2.46749099
18Type II lissencephaly (HP:0007260)2.43969640
19Pendular nystagmus (HP:0012043)2.42193187
20Agnosia (HP:0010524)2.41982344
21Nephrogenic diabetes insipidus (HP:0009806)2.40800578
22Abnormal hair whorl (HP:0010721)2.39523734
23Intestinal fistula (HP:0100819)2.38292846
24Genital tract atresia (HP:0001827)2.37237530
25Abnormality of the labia minora (HP:0012880)2.36475364
26Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.32575794
27Abnormality of alanine metabolism (HP:0010916)2.32575794
28Hyperalaninemia (HP:0003348)2.32575794
29Abnormality of binocular vision (HP:0011514)2.29162869
30Diplopia (HP:0000651)2.29162869
31Rectal fistula (HP:0100590)2.29074012
32Rectovaginal fistula (HP:0000143)2.29074012
33Prostate neoplasm (HP:0100787)2.28130918
34Gaze-evoked nystagmus (HP:0000640)2.28003893
35Abnormality of the renal cortex (HP:0011035)2.27552991
36Intestinal atresia (HP:0011100)2.27181678
37Progressive inability to walk (HP:0002505)2.27035668
38Attenuation of retinal blood vessels (HP:0007843)2.26083900
39Atonic seizures (HP:0010819)2.24472672
40Vaginal atresia (HP:0000148)2.23947468
41Abnormality of the renal medulla (HP:0100957)2.23125944
42Aplasia/Hypoplasia of the tibia (HP:0005772)2.20470527
43Clubbing of toes (HP:0100760)2.20228621
44Short tibia (HP:0005736)2.20050648
45Hypoplasia of the fovea (HP:0007750)2.19339090
46Aplasia/Hypoplasia of the fovea (HP:0008060)2.19339090
47Increased CSF lactate (HP:0002490)2.18692549
48Duplication of thumb phalanx (HP:0009942)2.18386908
49Gastroesophageal reflux (HP:0002020)2.18092009
50Gastrointestinal atresia (HP:0002589)2.17569232
51Aplasia/Hypoplasia of the tongue (HP:0010295)2.14954344
52Lip pit (HP:0100267)2.14651506
53Astigmatism (HP:0000483)2.11337160
54Long nose (HP:0003189)2.11090754
55Progressive cerebellar ataxia (HP:0002073)2.10063920
56Poor coordination (HP:0002370)2.08682957
57Methylmalonic acidemia (HP:0002912)2.06727856
58Abnormality of the pons (HP:0007361)2.05643360
59Abnormality of the fovea (HP:0000493)2.05279715
60Papillary thyroid carcinoma (HP:0002895)2.04638173
61Molar tooth sign on MRI (HP:0002419)2.04546808
62Abnormality of midbrain morphology (HP:0002418)2.04546808
63Glioma (HP:0009733)2.04403230
64Mutism (HP:0002300)2.03514107
65Hypoplasia of the pons (HP:0012110)2.02311715
66Ependymoma (HP:0002888)2.01688184
67Abnormality of the duodenum (HP:0002246)2.01323875
68Cystic liver disease (HP:0006706)1.99456606
69Partial duplication of thumb phalanx (HP:0009944)1.99183961
70Renal cortical cysts (HP:0000803)1.98689104
71Abnormality of DNA repair (HP:0003254)1.97253413
72Type I transferrin isoform profile (HP:0003642)1.96152411
73Supernumerary spleens (HP:0009799)1.95834951
74Cerebellar dysplasia (HP:0007033)1.95792306
75Astrocytoma (HP:0009592)1.93446792
76Abnormality of the astrocytes (HP:0100707)1.93446792
77Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.93401769
78Abnormal protein N-linked glycosylation (HP:0012347)1.93401769
79Abnormal protein glycosylation (HP:0012346)1.93401769
80Abnormal glycosylation (HP:0012345)1.93401769
81Hepatocellular necrosis (HP:0001404)1.93291854
82Sclerocornea (HP:0000647)1.92846754
83Aqueductal stenosis (HP:0002410)1.91425322
84Abnormality of chromosome stability (HP:0003220)1.91187781
85Focal seizures (HP:0007359)1.90507871
86Dyskinesia (HP:0100660)1.90144814
87Acute encephalopathy (HP:0006846)1.89342108
88Inability to walk (HP:0002540)1.87651465
89Abolished electroretinogram (ERG) (HP:0000550)1.87446979
90Nephroblastoma (Wilms tumor) (HP:0002667)1.87149636
91Inappropriate behavior (HP:0000719)1.86203886
92Mitochondrial inheritance (HP:0001427)1.86004311
93Increased serum lactate (HP:0002151)1.85969895
94Tubulointerstitial nephritis (HP:0001970)1.85578652
95Chronic diarrhea (HP:0002028)1.84086559
96Abnormality of the carotid arteries (HP:0005344)1.84045622
97Large for gestational age (HP:0001520)1.83263955
98Dandy-Walker malformation (HP:0001305)1.82239980
99Anteriorly placed anus (HP:0001545)1.81641703
100Embryonal renal neoplasm (HP:0011794)1.81451130
101Split foot (HP:0001839)1.81411967
102Pancreatic islet-cell hyperplasia (HP:0004510)1.81155683
103Absent speech (HP:0001344)1.80487903
104Hepatic necrosis (HP:0002605)1.80228563
105Postaxial foot polydactyly (HP:0001830)1.79367221
106CNS demyelination (HP:0007305)1.78813414
107Bifid tongue (HP:0010297)1.77073520
108Oligodactyly (hands) (HP:0001180)1.76705860
109Short middle phalanx of the 5th finger (HP:0004220)1.76166782
110Medulloblastoma (HP:0002885)1.76102842
111Acute necrotizing encephalopathy (HP:0006965)1.75721610
112Abnormality of incisor morphology (HP:0011063)1.74975081
113Retinal dysplasia (HP:0007973)1.74896316
114Preaxial hand polydactyly (HP:0001177)1.74613449
115Abnormal biliary tract physiology (HP:0012439)1.74310146
116Bile duct proliferation (HP:0001408)1.74310146
117Increased corneal curvature (HP:0100692)1.73474973
118Keratoconus (HP:0000563)1.73474973
119IgM deficiency (HP:0002850)1.72528707
120Aganglionic megacolon (HP:0002251)1.72419641
121Broad-based gait (HP:0002136)1.72126178
122Arterial tortuosity (HP:0005116)1.71603334
123Abnormality of the pulmonary veins (HP:0011718)1.71419915
124Meckel diverticulum (HP:0002245)1.71182322
125Furrowed tongue (HP:0000221)1.70660069
126Partial duplication of the phalanx of hand (HP:0009999)1.69942542
127Anencephaly (HP:0002323)1.69703357
128Tubular atrophy (HP:0000092)1.69499145
129Methylmalonic aciduria (HP:0012120)1.68102174
130Aplasia/Hypoplasia of the uvula (HP:0010293)1.64345345
131Abnormality of the fingertips (HP:0001211)1.63367505
132Pancreatic fibrosis (HP:0100732)1.62805954
133Abnormality of the septum pellucidum (HP:0007375)1.62601303
134Hyperventilation (HP:0002883)1.62287314
135Optic nerve hypoplasia (HP:0000609)1.62279710
136Anal stenosis (HP:0002025)1.62032468
137Trigonocephaly (HP:0000243)1.60501702
138Small hand (HP:0200055)1.60055018
139Xerostomia (HP:0000217)1.59897079
140Abnormality of the columella (HP:0009929)1.59514719
141Anomalous pulmonary venous return (HP:0010772)1.57871358
142Generalized tonic-clonic seizures (HP:0002069)1.56774282
143Small intestinal stenosis (HP:0012848)1.56749022
144Duodenal stenosis (HP:0100867)1.56749022
145Abnormality of the right ventricle (HP:0001707)1.56608787
146Neoplasm of the adrenal cortex (HP:0100641)1.56289905
147Abnormal lung lobation (HP:0002101)1.55612399
148Widely spaced teeth (HP:0000687)1.55422167
149Abnormality of the ileum (HP:0001549)1.54434779
150Absent septum pellucidum (HP:0001331)1.54120242
151Absence seizures (HP:0002121)1.53473885
152Ectopic kidney (HP:0000086)1.52373796
153Abnormality of the preputium (HP:0100587)1.52279291
154Medial flaring of the eyebrow (HP:0010747)1.52107775
155Upper motor neuron abnormality (HP:0002127)1.52104910
156Abnormality of the renal collecting system (HP:0004742)1.50583822
157Metaphyseal dysplasia (HP:0100255)1.48968676
158Septo-optic dysplasia (HP:0100842)1.47851407
159Nasolacrimal duct obstruction (HP:0000579)1.47477065
160Sloping forehead (HP:0000340)1.47113424
161Fair hair (HP:0002286)1.46794929
162Aplasia involving forearm bones (HP:0009822)1.46712630
163Absent forearm bone (HP:0003953)1.46712630
164Impulsivity (HP:0100710)1.45898087
165Abnormality of ocular smooth pursuit (HP:0000617)1.45377784
166Orthostatic hypotension (HP:0001278)1.44601216
167Duplicated collecting system (HP:0000081)1.44519965
168Myelodysplasia (HP:0002863)1.43819276
169Increased IgM level (HP:0003496)1.42745820
170Chronic hepatic failure (HP:0100626)1.42600612

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK23.43857583
2CASK3.19518211
3TNIK3.10526486
4VRK12.87630593
5MKNK12.86970400
6MAP4K22.61058049
7TGFBR22.55959190
8CDC72.46630494
9NUAK12.26701696
10EIF2AK32.11121214
11TRIM281.99085758
12MAPK151.93080739
13NEK11.89610099
14BRD41.89576472
15BMPR1B1.88445708
16TSSK61.87644750
17BUB11.83283697
18CCNB11.74792779
19ZAK1.69906345
20NEK61.68901989
21MAP2K71.68283813
22YES11.65728865
23CLK11.64392753
24MAPK131.60781611
25PNCK1.53030701
26RIPK41.52170728
27SRPK11.49127935
28ACVR1B1.45892309
29PLK31.43837798
30GRK71.43511058
31ERBB31.41604949
32CDK31.33446311
33NTRK31.31493527
34DMPK1.26352900
35PLK21.25957820
36EIF2AK11.25367226
37FGFR21.23792332
38EPHA41.23250067
39AKT31.22190714
40ADRBK21.17302741
41TAF11.15881218
42SIK31.14547100
43PBK1.13338531
44WNK41.11249759
45STK391.10537267
46BLK1.10002249
47PAK31.07682434
48TEC1.06082470
49BCR1.05772599
50OXSR11.05418957
51CDK81.04952316
52CSNK1G11.04002637
53WEE11.02677419
54STK38L1.02656509
55ATR1.02113063
56CDK121.01849008
57FES1.01442942
58MST41.00859582
59FRK1.00659430
60PINK10.99425169
61SCYL20.99307659
62BCKDK0.97911826
63BMPR20.97380629
64CSF1R0.96968500
65CSNK1A1L0.95895261
66CSNK1G30.94387573
67CSNK1G20.93167435
68STK160.90789445
69CAMK1G0.88978360
70TXK0.87288538
71MAP3K120.85796188
72INSRR0.85348230
73CDK190.84694354
74SIK20.81393890
75ATM0.76958673
76VRK20.74010296
77PDK20.73393467
78MUSK0.73372323
79PRKCE0.70182460
80TAOK30.69254435
81OBSCN0.66324207
82FLT30.66276967
83MAPK70.66153309
84BRSK20.65241608
85MAPKAPK50.63132889
86CAMKK20.62238853
87ADRBK10.61162151
88PIK3CA0.60972433
89CHEK20.58329576
90PTK2B0.58322932
91WNK10.57675294
92TNK20.56587071
93BRSK10.56041229
94PLK40.54538465
95PHKG10.54235249
96PHKG20.54235249
97TLK10.54095745
98LYN0.52424741
99EIF2AK20.51016054
100STK30.50718391
101MARK30.50372080
102WNK30.50289358
103PLK10.50213585
104MAP3K40.50044221
105DYRK1A0.49695391
106PRKDC0.48758056
107TTK0.48537695
108PRKAA10.48330149
109CHEK10.48094139
110RAF10.47644525
111CAMK1D0.47343055
112NLK0.46558224
113CDK10.46071515
114NTRK20.44786474
115ITK0.43214718
116MAPK140.41725039
117CSNK1D0.40981925
118CSNK1A10.40875136
119ERBB40.40694324
120MAP3K130.40488256
121MELK0.39121852
122TGFBR10.38476915
123CDK20.38387427
124AURKB0.36484990
125GRK10.35622243
126BTK0.35047256
127PRKCQ0.34841909
128MAPK100.34358715
129GSK3B0.33899179
130PRKG10.33516398
131RPS6KA50.32688914
132CAMK2A0.32655171
133LCK0.32508467
134STK110.32094942
135NEK20.32060871
136DYRK20.32021222
137CSNK2A10.31047623
138RPS6KB10.29623414
139DAPK10.29466098
140PRKCG0.29429880
141PRKAA20.29036081

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.55459646
2Selenocompound metabolism_Homo sapiens_hsa004502.40221119
3Homologous recombination_Homo sapiens_hsa034402.36019856
4Nicotine addiction_Homo sapiens_hsa050332.25149280
5Butanoate metabolism_Homo sapiens_hsa006502.23619659
6Non-homologous end-joining_Homo sapiens_hsa034502.20471105
7Propanoate metabolism_Homo sapiens_hsa006402.15981673
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.09563037
9Mismatch repair_Homo sapiens_hsa034301.98771021
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.93224260
11One carbon pool by folate_Homo sapiens_hsa006701.92777206
12DNA replication_Homo sapiens_hsa030301.91363758
13Proteasome_Homo sapiens_hsa030501.73710027
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.73374065
15Nitrogen metabolism_Homo sapiens_hsa009101.67127100
16Fanconi anemia pathway_Homo sapiens_hsa034601.64705107
17Basal transcription factors_Homo sapiens_hsa030221.64039741
18Spliceosome_Homo sapiens_hsa030401.63849507
19RNA degradation_Homo sapiens_hsa030181.56137118
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.54009646
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.49251972
22Morphine addiction_Homo sapiens_hsa050321.47045640
23Cell cycle_Homo sapiens_hsa041101.43219358
24RNA polymerase_Homo sapiens_hsa030201.42506313
25Nucleotide excision repair_Homo sapiens_hsa034201.38293774
26Fatty acid elongation_Homo sapiens_hsa000621.31467020
27Glutamatergic synapse_Homo sapiens_hsa047241.28512228
28Oxidative phosphorylation_Homo sapiens_hsa001901.26615949
29Circadian entrainment_Homo sapiens_hsa047131.26174960
30Primary bile acid biosynthesis_Homo sapiens_hsa001201.26029567
31Taste transduction_Homo sapiens_hsa047421.25443306
32Peroxisome_Homo sapiens_hsa041461.24254010
33GABAergic synapse_Homo sapiens_hsa047271.22931737
34Serotonergic synapse_Homo sapiens_hsa047261.22295878
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.22120860
36Tryptophan metabolism_Homo sapiens_hsa003801.15216927
37Parkinsons disease_Homo sapiens_hsa050121.14631893
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.14309036
39Phototransduction_Homo sapiens_hsa047441.13109998
40Base excision repair_Homo sapiens_hsa034101.12307619
41RNA transport_Homo sapiens_hsa030131.11693937
42Amphetamine addiction_Homo sapiens_hsa050311.10978815
43Cysteine and methionine metabolism_Homo sapiens_hsa002701.10617011
44Long-term potentiation_Homo sapiens_hsa047201.10408561
45Linoleic acid metabolism_Homo sapiens_hsa005911.09237080
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.07354044
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06436773
48African trypanosomiasis_Homo sapiens_hsa051431.03870646
49Caffeine metabolism_Homo sapiens_hsa002321.02098390
50Oocyte meiosis_Homo sapiens_hsa041140.98691054
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97821056
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.97108587
53Olfactory transduction_Homo sapiens_hsa047400.95785179
54Dopaminergic synapse_Homo sapiens_hsa047280.93564485
55Colorectal cancer_Homo sapiens_hsa052100.93439527
56Calcium signaling pathway_Homo sapiens_hsa040200.92892040
57Regulation of autophagy_Homo sapiens_hsa041400.92040059
58Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.91104068
59Fatty acid metabolism_Homo sapiens_hsa012120.91069776
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90541829
61Circadian rhythm_Homo sapiens_hsa047100.90370976
62Steroid biosynthesis_Homo sapiens_hsa001000.90083991
63Herpes simplex infection_Homo sapiens_hsa051680.89530776
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.89422172
65Long-term depression_Homo sapiens_hsa047300.88533327
66Synaptic vesicle cycle_Homo sapiens_hsa047210.88327593
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86350948
68mRNA surveillance pathway_Homo sapiens_hsa030150.85402594
69Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.84618354
70Pyruvate metabolism_Homo sapiens_hsa006200.84017813
71Lysine degradation_Homo sapiens_hsa003100.83209709
72Salivary secretion_Homo sapiens_hsa049700.82404236
73Huntingtons disease_Homo sapiens_hsa050160.82076249
74Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82019620
75Alcoholism_Homo sapiens_hsa050340.81898571
76Graft-versus-host disease_Homo sapiens_hsa053320.81770166
77Ether lipid metabolism_Homo sapiens_hsa005650.81727810
78Cholinergic synapse_Homo sapiens_hsa047250.81221941
79Oxytocin signaling pathway_Homo sapiens_hsa049210.80971273
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.80647443
81Sulfur metabolism_Homo sapiens_hsa009200.79737285
82Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79379856
83Protein export_Homo sapiens_hsa030600.78490516
84Renin secretion_Homo sapiens_hsa049240.77865697
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77114702
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76962976
87ABC transporters_Homo sapiens_hsa020100.75231712
88Measles_Homo sapiens_hsa051620.74963067
89B cell receptor signaling pathway_Homo sapiens_hsa046620.74358712
90Vitamin B6 metabolism_Homo sapiens_hsa007500.74169864
91Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73488024
92beta-Alanine metabolism_Homo sapiens_hsa004100.72409589
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71874969
94Wnt signaling pathway_Homo sapiens_hsa043100.71788995
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70206672
96Fatty acid degradation_Homo sapiens_hsa000710.70036072
97Insulin secretion_Homo sapiens_hsa049110.69424469
98Metabolic pathways_Homo sapiens_hsa011000.69395281
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69097592
100Hematopoietic cell lineage_Homo sapiens_hsa046400.68535609
101cAMP signaling pathway_Homo sapiens_hsa040240.67654228
102Type I diabetes mellitus_Homo sapiens_hsa049400.66725954
103Rheumatoid arthritis_Homo sapiens_hsa053230.66625860
104Epstein-Barr virus infection_Homo sapiens_hsa051690.66378572
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66315043
106NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66160090
107MAPK signaling pathway_Homo sapiens_hsa040100.66082442
108Systemic lupus erythematosus_Homo sapiens_hsa053220.65515473
109Allograft rejection_Homo sapiens_hsa053300.64735943
110Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63797684
111Autoimmune thyroid disease_Homo sapiens_hsa053200.63165757
112Purine metabolism_Homo sapiens_hsa002300.63023749
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.62840361
114Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.62491315
115Glutathione metabolism_Homo sapiens_hsa004800.62406973
116Other glycan degradation_Homo sapiens_hsa005110.62351130
117Sulfur relay system_Homo sapiens_hsa041220.62107111
118Adherens junction_Homo sapiens_hsa045200.61303939
119Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61251559
120cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61169692
121Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.61011337
122p53 signaling pathway_Homo sapiens_hsa041150.60681121
123Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59993926
124Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59870914
125Osteoclast differentiation_Homo sapiens_hsa043800.59600813
126Choline metabolism in cancer_Homo sapiens_hsa052310.58362328
127Inositol phosphate metabolism_Homo sapiens_hsa005620.57980656
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57921266
129Alzheimers disease_Homo sapiens_hsa050100.57731431
130Glycosaminoglycan degradation_Homo sapiens_hsa005310.57247984
131HTLV-I infection_Homo sapiens_hsa051660.56775521
132Chemical carcinogenesis_Homo sapiens_hsa052040.54345878
133Axon guidance_Homo sapiens_hsa043600.54285007
134Toll-like receptor signaling pathway_Homo sapiens_hsa046200.53769882
135Sphingolipid metabolism_Homo sapiens_hsa006000.53228649
136Pancreatic secretion_Homo sapiens_hsa049720.53199237
137GnRH signaling pathway_Homo sapiens_hsa049120.52605287
138Chemokine signaling pathway_Homo sapiens_hsa040620.51831232
139Hepatitis B_Homo sapiens_hsa051610.50990883
140Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50458900
141Pathways in cancer_Homo sapiens_hsa052000.50084021
142Primary immunodeficiency_Homo sapiens_hsa053400.50044736
143T cell receptor signaling pathway_Homo sapiens_hsa046600.49090658
144Retinol metabolism_Homo sapiens_hsa008300.49006816
145Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48175491
146Pyrimidine metabolism_Homo sapiens_hsa002400.48156635
147Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47881353
148Ras signaling pathway_Homo sapiens_hsa040140.47153456
149Influenza A_Homo sapiens_hsa051640.46322747
150N-Glycan biosynthesis_Homo sapiens_hsa005100.46148400
151Hedgehog signaling pathway_Homo sapiens_hsa043400.41744200
152Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41495178
153Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40163780
154Cardiac muscle contraction_Homo sapiens_hsa042600.39192209
155Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.38568526
156Glycerolipid metabolism_Homo sapiens_hsa005610.32482584
157Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.31898882
158Basal cell carcinoma_Homo sapiens_hsa052170.31835877
159Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30768804
160Hippo signaling pathway_Homo sapiens_hsa043900.29686852
161TGF-beta signaling pathway_Homo sapiens_hsa043500.29108740

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